<SEC-DOCUMENT>0000318154-21-000045.txt : 20211103
<SEC-HEADER>0000318154-21-000045.hdr.sgml : 20211103
<ACCEPTANCE-DATETIME>20211102200839
ACCESSION NUMBER:		0000318154-21-000045
CONFORMED SUBMISSION TYPE:	10-Q
PUBLIC DOCUMENT COUNT:		82
CONFORMED PERIOD OF REPORT:	20210930
FILED AS OF DATE:		20211103
DATE AS OF CHANGE:		20211102

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AMGEN INC
		CENTRAL INDEX KEY:			0000318154
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				953540776
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		10-Q
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37702
		FILM NUMBER:		211373225

	BUSINESS ADDRESS:	
		STREET 1:		ONE AMGEN CENTER DRIVE
		CITY:			THOUSAND OAKS
		STATE:			CA
		ZIP:			91320
		BUSINESS PHONE:		(805)447-1000

	MAIL ADDRESS:	
		STREET 1:		ONE AMGEN CENTER DRIVE
		CITY:			THOUSAND OAKS
		STATE:			CA
		ZIP:			91320

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AMGEN
		DATE OF NAME CHANGE:	19870305
</SEC-HEADER>
<DOCUMENT>
<TYPE>10-Q
<SEQUENCE>1
<FILENAME>amgn-20210930.htm
<DESCRIPTION>10-Q
<TEXT>
<XBRL>
<?xml version="1.0" ?><!--XBRL Document Created with Wdesk from Workiva--><!--Copyright 2021 Workiva--><!--r:e5235af6-2e2c-44cc-b741-bc0b6d42fa8f,g:5c86b37c-c57f-4c71-acc2-468d6efa37c1,d:0b2dd96150e340208a57faec23ec2da5--><html xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ix="http://www.xbrl.org/2013/inlineXBRL" xmlns:dei="http://xbrl.sec.gov/dei/2021" xmlns:srt="http://fasb.org/srt/2021-01-31" xmlns="http://www.w3.org/1999/xhtml" xmlns:ixt="http://www.xbrl.org/inlineXBRL/transformation/2020-02-12" xmlns:exch="http://xbrl.sec.gov/exch/2021" xmlns:amgn="http://www.amgen.com/20210930" xmlns:country="http://xbrl.sec.gov/country/2021" xmlns:ixt-sec="http://www.sec.gov/inlineXBRL/transformation/2015-08-31" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:currency="http://xbrl.sec.gov/currency/2021" xmlns:iso4217="http://www.xbrl.org/2003/iso4217" xmlns:us-gaap="http://fasb.org/us-gaap/2021-01-31" xml:lang="en-US"><head><meta http-equiv="Content-Type" content="text/html"/>


<title>amgn-20210930</title></head><body><div style="display:none"><ix:header><ix:hidden><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:EntityCentralIndexKey" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80L2ZyYWc6NTgwMmNmMDJkMTM4NDg3ZWJmNDg2NDU2MGNiYjcyNGIvdGFibGU6YWI4YjQzYzVhOGZlNDIzNGIzOTk3Njc2OWY1MmQyYzQvdGFibGVyYW5nZTphYjhiNDNjNWE4ZmU0MjM0YjM5OTc2NzY5ZjUyZDJjNF8yLTEtMS0xLTA_a259e83e-1971-42a8-944f-101c820bef02">0000318154</ix:nonNumeric><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:AmendmentFlag" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80L2ZyYWc6NTgwMmNmMDJkMTM4NDg3ZWJmNDg2NDU2MGNiYjcyNGIvdGFibGU6YWI4YjQzYzVhOGZlNDIzNGIzOTk3Njc2OWY1MmQyYzQvdGFibGVyYW5nZTphYjhiNDNjNWE4ZmU0MjM0YjM5OTc2NzY5ZjUyZDJjNF8zLTEtMS0xLTA_b289863b-5dce-449f-baa8-fb48283e794a">false</ix:nonNumeric><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:DocumentFiscalYearFocus" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80L2ZyYWc6NTgwMmNmMDJkMTM4NDg3ZWJmNDg2NDU2MGNiYjcyNGIvdGFibGU6YWI4YjQzYzVhOGZlNDIzNGIzOTk3Njc2OWY1MmQyYzQvdGFibGVyYW5nZTphYjhiNDNjNWE4ZmU0MjM0YjM5OTc2NzY5ZjUyZDJjNF81LTEtMS0xLTU0MTIy_2838faf5-3e6f-457b-b16c-d9137b17e940">2021</ix:nonNumeric><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:DocumentFiscalPeriodFocus" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80L2ZyYWc6NTgwMmNmMDJkMTM4NDg3ZWJmNDg2NDU2MGNiYjcyNGIvdGFibGU6YWI4YjQzYzVhOGZlNDIzNGIzOTk3Njc2OWY1MmQyYzQvdGFibGVyYW5nZTphYjhiNDNjNWE4ZmU0MjM0YjM5OTc2NzY5ZjUyZDJjNF81LTEtMS0xLTA_7639efbf-99c5-416f-bfb6-5c0f4255e294">Q3</ix:nonNumeric><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" format="ixt:date-month-day" name="dei:CurrentFiscalYearEndDate" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80L2ZyYWc6NTgwMmNmMDJkMTM4NDg3ZWJmNDg2NDU2MGNiYjcyNGIvdGFibGU6YWI4YjQzYzVhOGZlNDIzNGIzOTk3Njc2OWY1MmQyYzQvdGFibGVyYW5nZTphYjhiNDNjNWE4ZmU0MjM0YjM5OTc2NzY5ZjUyZDJjNF82LTEtMS0xLTA_b43fb2e1-fba2-4961-a541-d1237c96ee9e">12/31</ix:nonNumeric></ix:hidden><ix:references xml:lang="en-US"><link:schemaRef xlink:type="simple" xlink:href="amgn-20210930.xsd"></link:schemaRef></ix:references><ix:resources><xbrli:context id="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i0be1039089ac48b9949c7220072783f8_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="dei:EntityListingsExchangeAxis">exch:XNGS</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i7aae778309b84991a0bcd8e16938fcf6_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="dei:EntityListingsExchangeAxis">exch:XNGS</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">amgn:A1.250SeniorNotesDue2022Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="if48b7c2672244974ae505e9c06ea1da9_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="dei:EntityListingsExchangeAxis">exch:XNGS</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">amgn:A2.00SeniorNotesDue2026Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:unit id="shares"><xbrli:measure>xbrli:shares</xbrli:measure></xbrli:unit><xbrli:context id="id260522a4d634e208edb416383a7443e_I20211028"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:instant>2021-10-28</xbrli:instant></xbrli:period></xbrli:context><xbrli:unit id="usd"><xbrli:measure>iso4217:USD</xbrli:measure></xbrli:unit><xbrli:context id="i237db287808149dc88791dd0402e8c8d_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="icc3aae43096e4ee2941dfecfdc9776ad_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i3eb445431b634cc6b3e61727cef7b877_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i556e038dae96477cbe84bc1653ed5883_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i488eb65c564543e1895d64ea848f40c4_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductAndServiceOtherMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="id0ffdac343f944aaa636865f0a68567e_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductAndServiceOtherMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="iddf8eed0ade74615b203cae47895e098_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductAndServiceOtherMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ia3ba4d704ab343159b80e5ecde0bf68b_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductAndServiceOtherMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i5c9f553a648c448983067995570fff40_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:unit id="usdPerShare"><xbrli:divide><xbrli:unitNumerator><xbrli:measure>iso4217:USD</xbrli:measure></xbrli:unitNumerator><xbrli:unitDenominator><xbrli:measure>xbrli:shares</xbrli:measure></xbrli:unitDenominator></xbrli:divide></xbrli:unit><xbrli:context id="if5d69d61a77e45e8a5690b1247306be3_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i091ea451ee5b401e9a692e47a31d079b_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i85eb1be2504f43d5b6b300dc199131eb_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i8fd3f59d080644dfb1308254046fba14_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iaea9ac2193424d918f03fbf56ef30362_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ia7cc3209b62b4e859989adf72041bfb0_D20210101-20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i8ff5ee6ed2904950abde3e69e298a888_D20210101-20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i7969d970f6a54e60804bc95280496c8b_D20210101-20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i2dcd4eff17124be29dcc8becb0415e77_D20210101-20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ib60c8e3ee5494c37bc18cec8bd0c619c_I20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-03-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i79a13e6805f34de1abc4d45f73bf3010_I20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-03-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ifd05c4dcf2974888bb7ea94987a2302e_I20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-03-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i02d7483a082146bca57a490cca649110_I20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-03-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i65ba920729294b6ca0d58b7c3d55da64_I20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:instant>2021-03-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i7a34b44a0b684692a8ce01f962435f05_D20210401-20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-04-01</xbrli:startDate><xbrli:endDate>2021-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="if25ef868ecd240a3b1467e666429713f_D20210401-20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2021-04-01</xbrli:startDate><xbrli:endDate>2021-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ic34d84ceeae14872821180cf4d7c1fc9_D20210401-20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-04-01</xbrli:startDate><xbrli:endDate>2021-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ibcaee6c81e1645c98fc9f7046d1c84b0_D20210401-20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-04-01</xbrli:startDate><xbrli:endDate>2021-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i2ed57ff3dbc9401b9e0afd3df0e57952_D20210401-20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-04-01</xbrli:startDate><xbrli:endDate>2021-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ib91fd46e082e435c8604678dba5c6807_I20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-06-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i3ee32787b0ee44f7835a1897d7ccc133_I20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-06-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ib9c55bd482c8427c869df819585fe64b_I20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-06-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i9d079f6d807e45a8b0ea7b4bf5ca1b1c_I20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-06-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ibb4ad07750104a41ad551ce7e97f7afe_I20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:instant>2021-06-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i6271ffbf65cf467783eea9a8f4a54fb0_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i984e708e2ca94952a077181e38e25d78_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i967296e305e04ee0ba9de8194bd5c859_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ia9f1d012da3a43b89a1c71ec6c7599ff_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i326b605172394be1a3158d27be23c5d3_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id005bde0830f48398b26dea00beb0a27_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i3deeda31d541496fbfdcf359358e2e31_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ic860f31327384ad08f5dbf6d59cdb763_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i9383ea8be6554a1fab020c889f98f560_I20191231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2019-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i9fa8d9073cbb4a5e8bd57d0450a06268_I20191231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2019-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i27c34688721e4c3eab67f6dfab55e1ea_I20191231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2019-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i3b1542b7bb8c42d092dd7b4a59e1c916_I20191231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2019-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id63942c02328404c8dac62b9840ef120_I20191231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:instant>2019-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iac88abda0f2a4f44ab3e6e7248813631_I20191231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:CumulativeEffectPeriodOfAdoptionAxis">srt:CumulativeEffectPeriodOfAdoptionAdjustmentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2019-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i093220b291f2482d91c2fbc2c9ffff00_I20191231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:CumulativeEffectPeriodOfAdoptionAxis">srt:CumulativeEffectPeriodOfAdoptionAdjustmentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2019-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ic041513a75144cdd9d651b4d92760425_D20200101-20200331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i1203a51d54b041baa767dda74da28ae7_D20200101-20200331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i2ce25f9016044114882e77dd2ae1c3db_D20200101-20200331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i8d2a343e4cc5455eb9ba7ef31b5fc432_D20200101-20200331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ibc414a46e88b4e40a79c00cb9bfd0717_I20200331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-03-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i8ff21ac5e59f4e1c9aaf71c8a6427a9b_I20200331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-03-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ieb7177b91ced43c4bb32d3c71fc60664_I20200331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-03-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i9ab337ca3f8b490685a1514d21ef0795_I20200331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-03-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i97aafa8c1ca149ab98952ad235869d3d_I20200331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:instant>2020-03-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iad1c7381eead460f9f20a42237bbc0ab_D20200401-20200630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-04-01</xbrli:startDate><xbrli:endDate>2020-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2020-04-01</xbrli:startDate><xbrli:endDate>2020-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ia9f6aa7d77f443dfb9ccbbf4060d7af0_D20200401-20200630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-04-01</xbrli:startDate><xbrli:endDate>2020-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="if8027892520a4ca5bd94f4c5cfcec8a0_D20200401-20200630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-04-01</xbrli:startDate><xbrli:endDate>2020-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i7896d230ca994182af0336d7fc0f319c_D20200401-20200630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-04-01</xbrli:startDate><xbrli:endDate>2020-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ia393209bc348462397965e66e877a084_I20200630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-06-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i8a3527abf717402c896edf9e49b60c2b_I20200630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-06-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i9c61b9be9ad3458088feb12ba9d330d6_I20200630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-06-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ib5bc8ed5ffb54e45bdec39111af0f8d5_I20200630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-06-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i0d016fa4aa4b4b0b8d61f8f03d2b1ad9_I20200630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:instant>2020-06-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i2fdcbf2c5023490a8467f390d0945384_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ia0027870c8424e858af8516bb7a32d5b_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ia750b0fd2e8d494f82d6c68132072625_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="if9b3a6e30225464792dc4e6abbd3a015_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="id0c6f5eb460b4312bb606fc4ad30a816_I20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i7ca21439af704771b81a4e07e28ca15c_I20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i18ba9dc7e2ca40f5b5ccd5e684f54c7a_I20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i5368a3d307444f2c801d6b1d0963ec11_I20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i1a997bb47af74377a26fb3c2164ec5a6_I20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:instant>2020-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:unit id="segment"><xbrli:measure>amgn:segment</xbrli:measure></xbrli:unit><xbrli:context id="i65976c78d95c49118311d26eb3256876_D20210416-20210416"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:FivePrimeTherapeuticsIncMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-04-16</xbrli:startDate><xbrli:endDate>2021-04-16</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ifd83e7d77b084c5d854ddc58d39a3bcf_I20210416"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:FivePrimeTherapeuticsIncMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-04-16</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ic6cdb58f08f6497e9571e255839b182e_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="idb19909eae6245c0b192e54299cbf115_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="iff8d101adf4b402f8cf46cf5dcd93486_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i8c7cf69cd4834e9c85f4459b2de8d602_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i881925882b374e84accf889451f21493_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i3580e2b0cb29470bad2033dc2b011286_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i928ab90d0db745ea81bb2a93d965f16e_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ia5bb4cc11d6c483d8309a8c954255a3c_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i5ad790cbfd31467bb8daa208b16d7e6e_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="iee4b7620a6e94b15a0ee2efa21046c26_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ic41a377f5b39468994f26d4f4fb0aa51_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i9e2067897ce84b959d0906d105ab21e8_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ica2c1ae056384bd5808311f2c76005bd_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i1e4fbb00243e4f62ba164169062363bd_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="id03562c57df94c4695307d990b6d880d_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ie59bcfe33b8147c0b1c58739ec6f4501_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i7d0db737d136412cabc053873e3c0f55_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i997de67b4d8041fd92aa65650ae56646_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i6be8feef3fae4c3ab81bc1a648281c8c_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ib1e795008cb04855b4f4ada989eec622_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i7fb5d6e70e864ca9a24965da716a59f9_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i8f5c65603d3b495a97c04bb49c2930c7_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="if2f93bdf48274317b1da0bbaad739897_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i6d80e26ad167494498b23e0ca5271458_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i17187759eba94aadb3d31a3510ebf19e_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i641be115cab64df981d42cdd9261ce71_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i368f295d54bd4525bb8eb6714d3d0066_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="icf361ee93a5a459fb961382bfdaab897_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="iae3f58a4ca5c4ee6b7a5efa557d3239e_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i89c0f0d97cef4bd6b1184caf279f571a_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i739f696b931d4702b3df5ae6ca746716_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="if968e6327f794c59a9ba65fc3208a8f6_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ic9d9abb7215c47c2a1aca1be0668980f_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i5b3ef1a8e7f545cfa45814ef6cc1e9ef_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i65474b7854d64aadbcea001bcca67fcc_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="id84e814556764ab79f45c36978bd96e4_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i39b00b7d625e4f6487ec0db17bdc442d_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i817db5726ac748d4bd491dbef24298e8_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="if48659bf944e4492a4dafa719e7083d0_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i7b514b2a404649a58ac1b9f9087c9ed6_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i69c93666703d4eac86caffd587b7db7d_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i0dea61c77564492ab39c0a6ee2a71ffb_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i643c94b54a124674bdf0a819e67e429b_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i21f6d8435c474c6980866635aeee71e9_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i0c97db9ff3494e8c8961a94b3979974b_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i36d299d1d5a642cca156e5411c4b4fc8_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ifadfb5ce284249b49c5b541e46f8fd6d_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ibb9fffae57f44694bf945745287d733a_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i2f0871bad93240bd851a8f0aaa387350_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i10acdfdcf69c40c2a0bdc6d3e81fb337_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i23817bdf825e4ae1ac3362ea0639d136_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i0beb71107b234faea29110b3fa9d8a98_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ic81b8501b6db4aee88091da6a3afdf07_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="if807b6245b86445088eb952987a6b469_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ia3c6be49d4364b1f9f7490f5b324e697_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i2032ce010c324b94be367952c9e7ba79_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i8b0da7f54b9d44ec896bac0ef1d0eb58_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i05cbea6753bb40cc89759fbeb6e01550_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ia48b8184147044458082feb5ea147e49_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i99ffbf75ddf84e1e9245421a8c01d767_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="idab45a332369432d9ebd6f50b96a8f56_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ica6caa6433a24945a279239a702b2abf_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ic1bb05a1b59b4da5902e961b2a5533a0_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i7cbcc55bfaff415a96eaa73c996dbb6a_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="iaf3073b6b8e349c9b88d3cb4f719e628_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ib9e71fbc76704655955f107a3a191a9c_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ide3ecdc601c44f8d89456132330e9af2_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i17357cd18fe541d0a042e9ee59c93b38_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ib3777a2c9f034e97919676bb7754de25_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i6b5f2a9043d945b08ec0167f3cfed9f2_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i95957399b3a14e7383788a66404fcbbb_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i78293d5fa71b41ef9cc01a231545bab2_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i195420e0531242db9f936a0127259be3_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="if0fb79f0bfbc4e51b7cb42fd1d71c840_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i68bf0dc18c0d4ffa9e9a898ff74c54f1_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ibe1bd36ce26a43fe9cb844c7326c4e54_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i7da33cf805a445869662f5abc2106d6d_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ia6106c345460401c9e03019b7c080699_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i443bd36291d548a0aa9856e73206eac6_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="id7ca09709e904974a92ad3adb8b9fd77_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i98005524cd124b8c966a68f6bdcfb8fc_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i5b4401a3903c4c908d2eb7fe95caad21_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i3cd61c0be22f4420b7238ce5a6df9130_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="iae6381714cfe468aa29ce147540ec7e9_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i96040b94405a4bd1a72890459e71ee00_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="iad909099174b42f681a09827cb78f0a7_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i9445f98f484747b89af2e9d73ea09d95_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ib01fa4a797464e63b788127b5705e442_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i4f38a5540cd04d718fff14e7bd440bf3_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ia48c696724e24052ae23b516c63d79e2_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ic91169bf44324e9c8beba26b3f9827e7_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i749f9c098fc64abb9167bd96645abed7_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="id2cb108abc1b4ddc9555fa47ab4e573b_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i576d061a6ae043e0829b0988a7faa3ec_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ic52c02bf054740ada11032b24246ae68_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ic6cc0b13a201477e8bdc3a92299b7b68_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="id29b4587abfe4026b9589b04316507cb_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i99a4a03013b04d41935e841bd095d3a7_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i6a2c38f1abb049d190286ec739f3d8ae_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ieb422a6656b54be5afd83d1c3557841c_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="iee523348acf64084b9744fc397411af6_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ie2fb5db5ef234ceba2e63133b46811d9_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ia1236d7f1db54d0cbbb4bb10634d9cbd_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i700316332e8941abafe598d080cee8ed_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i2237615b64f7401e880801b52e994daf_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i3367f489225f42e490b5ec1bd448da76_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ie4393fb731674dae95e49ebf43c2dc17_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i2d608ed82a0642d2bd3d2585175ab0df_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i7ec4a6f423c548c287970aa87131e9c9_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i277af735bdea4ca1ad4911bd0724214d_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i547f36d7acb3432789479ca670e2143f_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i6ddfacf19b5b4634890a1b86f11498d4_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="iec4ac6803eb24d47ae70292430854aee_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i11c711a9331e402aa04c6f1100a9a662_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="icc040f113aa74ff9aa98ca66ae336cbf_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i03039f45f78c4280b4623c349760790f_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:unit id="number"><xbrli:measure>xbrli:pure</xbrli:measure></xbrli:unit><xbrli:context id="i91b6753ab42449599e1e80924db35109_I20210531"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:instant>2021-05-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="icb5563aa4d0b4e68b3266d16db71f2a1_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">amgn:KyowaKirinCoLtdMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i1dfc25edd9d84950bcbf296614e005a4_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">amgn:KyowaKirinCoLtdMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i0523566bb4bd4ac7a167861d41b07412_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i8db023e72bf0457098764c83dfe06255_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i3022e170e868460588b8873ad8b918de_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ic7d3b5bd8e574e95949520f4cff15af1_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i507488fbf87d4c6296eb13e3e0006fbf_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i8ba30f0c09fc4bfd9fe36a47079d2854_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i54f838959ac943e79d09dcf9e6faada4_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i84edbdc908bc4493a769cf963ac32f28_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i6a8d71c465184aa38c33193a90315560_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:AvailableForSalesInvestmentsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="if5d779b254da4c18b8454e5bf7051777_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:AvailableForSalesInvestmentsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ib2b89ed4eb094c5f966961837399b7ca_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ia0271b62203b4afbbefbea6461a32a14_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i88ba0aea99ef48b08518a135f9c253ef_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:BeiGeneMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ib7d74024b547459c9c043788d26b2171_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:BeiGeneMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i425bed6d2b57481aba5c27ce44f41234_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:BeiGeneMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i14a1d9538f0a492885a9966112c392aa_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:NeumoraTherapeuticsIncMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i3c3ace434f6b40b4a14815a09b06178b_D20210930-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:NeumoraTherapeuticsIncMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-09-30</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ic38268b0440c4532956b86d64e30b988_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:InvestmentTypeAxis">srt:PartnershipInterestMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueMeasuredAtNetAssetValuePerShareMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i84a786cd4d99438e85fec21c4c798f36_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:InvestmentTypeAxis">srt:PartnershipInterestMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueMeasuredAtNetAssetValuePerShareMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i01c954a7c8fa422990f7456e349536ec_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:InvestmentTypeAxis">srt:PartnershipInterestMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueMeasuredAtNetAssetValuePerShareMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i9a95e7ba909f487d97ae171134923478_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:InvestmentTypeAxis">srt:PartnershipInterestMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueMeasuredAtNetAssetValuePerShareMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i2fcb95887a864539b58641131094dfd5_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:InvestmentTypeAxis">srt:PartnershipInterestMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueMeasuredAtNetAssetValuePerShareMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i7d119868ff92459e8484a254322dda06_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:InvestmentTypeAxis">srt:PartnershipInterestMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueMeasuredAtNetAssetValuePerShareMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i9160bae8d5f74cf4a23fbe7ba32fa1b6_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:DevelopedTechnologyRightsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ibb2cb97dcaa2448f8abb52ea2809f752_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:DevelopedTechnologyRightsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iccda3c90f3ea4d7ca11b1e7e5979139f_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:LicensingAgreementsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i7bfe3a17c67f48848b0a262301253745_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:LicensingAgreementsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ie5cd36de21a24c3a974d783bc31683e3_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:MarketingRelatedIntangibleAssetsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ifa42c9c20230405db95ebc7c2717a086_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:MarketingRelatedIntangibleAssetsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i823fc181443240599bbbbaad667a7fd2_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">amgn:AcquiredResearchAndDevelopmentTechnologyRightsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i3c93fbbb176e41ab97226ab5c020020d_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">amgn:AcquiredResearchAndDevelopmentTechnologyRightsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i62a4ce9947344dd28aeec0db74164aef_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:IndefiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:InProcessResearchAndDevelopmentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i858e9c4fb9dc48f1b8c2568fc92c7dfd_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:IndefiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:InProcessResearchAndDevelopmentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i28a3a2e4d2f24ec1ab05429cee726f75_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:unit id="eur"><xbrli:measure>iso4217:EUR</xbrli:measure></xbrli:unit><xbrli:context id="i1d8b35fb400b4d018ac1fc3ac92c4e11_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iba85a821e6d84b96a52fc42ef1b75604_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ia88d5a3b1b5c414db7ff8890b7c96f91_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i1a04775f93b24e3c83787a805db33fd7_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSixFiveNotesDue2022Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i071cb4027c8549148b8bd96aea3e7c5c_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSixFiveNotesDue2022Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ib744f296eafb4f8d88d2a38efb8a48a3_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointSixTwoFivePercentNotesDue2022Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ie50a52f9a64743be865aca69358499b2_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointSixTwoFivePercentNotesDue2022Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id0d88ff8ca444d28a9d31155d2af6123_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:unit id="chf"><xbrli:measure>iso4217:CHF</xbrli:measure></xbrli:unit><xbrli:context id="iaccb7326e7d146e0aafad220d316b604_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id7b48ebaee8d4fddada565c9d549a4af_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id1e3e3f0ae1a4a3fb3b7e07bf050efd6_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i14cb17bbd31f41deb2c7c3feb4b40b34_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointSixTwoFivePercentNotesDue2024Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i3f99f7b28ace4d3b80f5f9385a149eaf_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointSixTwoFivePercentNotesDue2024Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i3e1c0c3571924fcf9795dd47036e02c4_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i1ad59cf770774b36883e5e3f187962e3_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ib8287a44e2c445c2acd186f4936f5772_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i6be009b691aa4576ac79c8915e21298d_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i35556fe1ea36409196d95de0bec85fae_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPercentEuroNotesDueTwoThousandTwentySixMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iee3ca7ca07cc4b1b82dc3946ebca7fda_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPercentEuroNotesDueTwoThousandTwentySixMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i52dee93b650b4cd8868ed20f7cf964bc_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSixZeroNotesDueTwoZeroTwoSixMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i98166ba2f34643ffafa2e088bf573187_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSixZeroNotesDueTwoZeroTwoSixMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ib9a2ddc95a504747aa69a99a4d875fea_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointFiveZeroPercentPoundSterlingNotesDue2026Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:unit id="gbp"><xbrli:measure>iso4217:GBP</xbrli:measure></xbrli:unit><xbrli:context id="ic87056a5fa024aba8b55cbd31c06353a_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointFiveZeroPercentPoundSterlingNotesDue2026Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i5285c4d278d54713b60c0cc0f87aa46a_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i6bb96c6e9f4048dfa94c91a4ab648b6a_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i705890d8cae541638f21f7669dbe4b04_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointTwoZeroNotesDue2027Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ieb62499093c345529236e71f444d0853_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointTwoZeroNotesDue2027Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ibda3099c78a845a98d23ce711d8447f6_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointSixFivePercent2028NotesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ibb2e9e5c4f2a4bbf841a6bc671651b19_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointSixFivePercent2028NotesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i407ab77f9d0440acae9fe2fc19c63542_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPercentPoundSterlingNotesDue2029Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i000f9a5c0b8f4cd99faa556d2ea850e6_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPercentPoundSterlingNotesDue2029Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ia3569d0c6bcd4203a1148cb8dda584fe_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointFourFivePercentNotesDue2030Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id46fc442a7f34ba2afc285c190d4a3c5_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointFourFivePercentNotesDue2030Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i2c54babb8e9f4eb8b43722a88181da66_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointThreeZeroPercentNotesDue2031Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i2f896bd90bd24cfcbf6f31271e9148e9_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointThreeZeroPercentNotesDue2031Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i220407dac7c34df4809bfc677b8b3503_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointZeroPercent2032NotesMemberMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i10faa7c13c3447bbbc7cfae536e3c802_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:SixPointThreeSevenFivePercentNotesDue2037Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ia6787d1b183a4eaf8408dbce1815a07c_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:SixPointThreeSevenFivePercentNotesDue2037Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iac7d798f49894466bc42c0153cdf0595_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:SixPointNineZeroPercentNotesDue2038Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ib5e6389f8cf6478dbebef3136cee8c23_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:SixPointNineZeroPercentNotesDue2038Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i512d102f92cd4cc2833291c7e8cd520d_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:SixPointFourZeroPercentNotesDue2039Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i6af736050aa24649ab1cfff13dee1b92_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:SixPointFourZeroPercentNotesDue2039Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i99981976037d4cef90e95f33441854b2_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointOneFivePercentNotesDue2040Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id540a747481347329775d9396bb889d2_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointOneFivePercentNotesDue2040Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i00fb0934241248439eae35efb4b7888e_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointSevenFivePercentNotesDue2040Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ib61d19755e0742c09a249871a640ecd1_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointSevenFivePercentNotesDue2040Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id14f137f4c5e454687d4fbce9656c938_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointEightZeroPercent2041NotesMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id4a29b7b702446d0b6a2302a87559c9a_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointNineFivePercentNotesDue2041Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i891f05772784463faf20ad97f433010d_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointNineFivePercentNotesDue2041Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i1175ce0d1778434ab2f82d1aeb58bf2e_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointOneFivePercentNotesDue2041Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iad10456565dc49e7bc078124e8cd8fe1_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointOneFivePercentNotesDue2041Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ia5815daee6a4476eba6259b8d47fe654_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointSixFivePercentNotesDue2042Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i5dfbce0b73c242c8baa5ce827dad9a2c_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointSixFivePercentNotesDue2042Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="if7316ee9f235452f8616207596971771_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointThreeSevenFivePercentNotesDue2043Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i1675c34a9e9f402db5c00ceb852bb0b6_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointThreeSevenFivePercentNotesDue2043Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i0fd6f6c0e19b45a0b4db95bced8c11a2_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i93a7eb973f5245969d84a7be7e597722_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ied462f3ca0734341b45ec582dc99c7cf_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i3a969d07d31f43ee8b8793eb8498e57b_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i27a15eba71944c9f9d27a09b187b5445_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointThreeSevenFivePercentNotesDue2050Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="if178d7d786ea47c094645c6a4aac66f9_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointThreeSevenFivePercentNotesDue2050Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iceaad247ba05416ca273ec699ead3eb8_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i36d572d0be7b4f45b4a95c96ad590314_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i2471f208310742da8d39936484269aa5_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:A300NotesDue20523002052NotesMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iabc69f9b3f0d4959883895ba0b604099_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:A300NotesDue20523002052NotesMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iab6eca48d1b2444986c10a3c8b80b044_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="if155164e9eda4b7494a946338f4c79fb_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i33b3f55471c04aefa2d6d4d4486a0ee1_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OtherNotesDue2097Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i98d314d0c5ac49429ee3c71c38d086dc_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OtherNotesDue2097Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i33a19bf9151948efb174bed3a79387f0_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ifc54ee979f3c450d94595dd648269176_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointSixFivePercent2028NotesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="id79db748ed1c48398fe671a31ee535e0_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointZeroPercent2032NotesMemberMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ie5587a9964dd43d2a6782cd812ea6608_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointEightZeroPercent2041NotesMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ic6452876c4b84f979e9f7d07007ec855_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:A300NotesDue20523002052NotesMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ia312c6387bbf40488704796f2339d92c_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:DebtSecuritiesPayableMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:RangeAxis">srt:MinimumMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ic5275f5bc2cf4d60a35166b9ec79a4c2_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:DebtSecuritiesPayableMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:RangeAxis">srt:MaximumMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i434c36284fce4b0fb4ec413faf8330f4_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointFourFivePercentNotesDue2030Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:VariableRateAxis">us-gaap:LondonInterbankOfferedRateLIBORMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i4eb0394fe4684ccdb9a301bd5115028c_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointThreeZeroPercentNotesDue2031Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:VariableRateAxis">us-gaap:LondonInterbankOfferedRateLIBORMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i461e1d1d258d4b4faf9c477a92b85a30_D20210301-20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2021-03-01</xbrli:startDate><xbrli:endDate>2021-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="iccfbc695297d4e6b87ea624adb1a3149_D20210901-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2021-09-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ib619731edd7541fe8568acd19da059d6_D20210601-20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2021-06-01</xbrli:startDate><xbrli:endDate>2021-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i57518655effb4de5bdcffb7396c85dc7_D20210701-20210731"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-07-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="idad3dab92e834ac98e9986b58ed4d7d9_D20201201-20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2020-12-01</xbrli:startDate><xbrli:endDate>2020-12-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i0f1af52b3cdc45b69ad881a053131e62_D20211001-20211031"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:SubsequentEventTypeAxis">us-gaap:SubsequentEventMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-10-01</xbrli:startDate><xbrli:endDate>2021-10-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i9b08bc2a35ad4f1b92f1a9c32d536e07_D20211208-20211208"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:StatementScenarioAxis">srt:ScenarioForecastMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-12-08</xbrli:startDate><xbrli:endDate>2021-12-08</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i770b083713ae40d5abf6f7e80c8202c5_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedTranslationAdjustmentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ic6813714a49c4e1ebb1c7f61614d435a_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i8bf4fb9fc5bc4ef5b53a1d2a4b2dbe24_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="if822d7ae834a4a6cbea8ec7441e99f34_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">amgn:AccumulatedOtherAdjustmentAttributabletoParentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ic640b9e0658f45ddb2d1866ae9c0d679_D20210101-20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedTranslationAdjustmentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i362a946d783d4675a1537219335e1ecf_D20210101-20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i3490a417c3664ea28df867c0b5b64b99_D20210101-20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i4f043f0296ab40adbbd000e3a19b8263_D20210101-20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">amgn:AccumulatedOtherAdjustmentAttributabletoParentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-03-31</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i3cb26c116a8243b290d914005b2701d7_I20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedTranslationAdjustmentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-03-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i1bc84cd5a4d7427f8ea0603f5c4fab36_I20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-03-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i12d709ededf44d88909a52a34d1b6465_I20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-03-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i36d381395cab48a3a0a38dacd23b095d_I20210331"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">amgn:AccumulatedOtherAdjustmentAttributabletoParentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-03-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i77c6d51206434679bcbf62756fdc2646_D20210401-20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedTranslationAdjustmentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-04-01</xbrli:startDate><xbrli:endDate>2021-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ic28cfd96645b4c7caed54e18d250141a_D20210401-20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-04-01</xbrli:startDate><xbrli:endDate>2021-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i132b85ef12554699b07d3501175ff54f_D20210401-20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-04-01</xbrli:startDate><xbrli:endDate>2021-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="if0969aa8ef414908986e6dbb1310e704_D20210401-20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">amgn:AccumulatedOtherAdjustmentAttributabletoParentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-04-01</xbrli:startDate><xbrli:endDate>2021-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ia5b73fcb215b4f1fb5f74cc40aac6a12_I20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedTranslationAdjustmentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-06-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="if425fe5fd2294df9a8d0f639c5037ec9_I20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-06-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id85f7578a3bc49ca89f363dce5fb32aa_I20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-06-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i0fdb28b3619543a79bc3b17b1cc0a2d4_I20210630"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">amgn:AccumulatedOtherAdjustmentAttributabletoParentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-06-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ief03f026e49a44918a54a590451e6db3_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedTranslationAdjustmentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i98ef59b24516466ebfc3d73a98308ecf_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i719883141b814809a34bc70ed81e53a0_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i45a15717cb5141c5864e39d52a2a95fc_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">amgn:AccumulatedOtherAdjustmentAttributabletoParentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ieede5746b0d64fdbbf75791dacc0ef9d_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedTranslationAdjustmentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i672a17c30f404de680e008be9b6464aa_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i9660b813f8e644d8b66ad3118538f278_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i24a9272b1ce44928aa5b6ba2a3c47e9f_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">amgn:AccumulatedOtherAdjustmentAttributabletoParentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i32d3947cf2c945deb867f411799b6962_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i671c24fb8d22406aa2608b0eaf66e7ea_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i605067db02764f2ca67c7def81eb8b61_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i956f0c0215934258b02d8cc62b9f996d_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i774914ff61704f25a808fe591907f07a_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i3bd653c39f1d495b9c484952593554a1_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i66702e11ddcd4d94b4f6a53b4231f09f_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ice9f1dfc8f83445b9b89ebcebe763f1a_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ibd9038c5b623433f87f5b5ece6980092_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i74e3224ed0df4d7b844d1e04f9657708_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="iba01b07f6b98472d83708a5396a4df3b_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i67a805bd27be4c1fb6e4f9f773fd62d8_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i7702c711db32401d9e72b707815b70d5_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="if763cdb48cee4124a55a518d0549ffcd_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ifd7b5626cee240a48eb61b6441030918_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="iee30caa26817491b92bd2d46a5a5214d_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i826a29ed0f7a402ea34f70df227b7521_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i7d76b8e7f94f45cc9e548d9fb2040f2d_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i37882f19b0784eccafabfe836dc51f25_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="if0fb1e0d683243249078c344db9e3287_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ie0b4aff0ec6c41e18c08f8a27f8d35d6_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i9bf07042070142818b2dcc65da76d130_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i1b770f2bad0a458bb80d6080d416e653_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i1b4470fbc2904831b9b368445e211ea4_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i33c195572dca4fbf824c6e47b083ab07_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i63f7d63505ec40e78832bd42bf718996_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i25e32e59bf21440087114ea6114b506b_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iab7f53e834574888ab2bc9ca340df3f0_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i668050cd480a44d59980ffd4209aa796_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i9d7900fb43d041f4bbfa2d693a513c61_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i222681c138f44598b25427e0b8ccae76_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="idb72f426587a4ec5befa804534b12722_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i25541eb9d6c34199be9b71a30ee0401d_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i9e90f12e90a449639d72687889f2e95a_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ied5df9df96c04c2ba41897fd892ef61f_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id8e22719623e4f98b17f615c76dbb3bd_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="icef3bcd64f2c4ba38b4e195178b28e0a_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i06db08463971480086be884f8fb2f0d5_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i891c6c71b8e7435ea6af4ad541a9f170_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i905b99ada59844fe9615f05632d936ba_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id43e4d99182d4a8fa11017c14d8cff33_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i0345015d43454b10b538d7fe7b901fa5_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i7d9048c66277472987f2e5c853ea849f_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="if46f80f8f61a471bbd2f2cd5ffc18024_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ifb485de2ab374debabfd24e341e4d676_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ibbe73c36ec8a41f991d38edd0c64bb47_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ib8fabc2c97464ca0bbc9f7eb0a1fce39_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i9c8094c8dc344979833ee0c0a4184c0f_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ic99616af30c6481c95e52063cc58aab7_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id4322deb32b242dc9dc95226e1f24e7a_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i5720d28c85fd42cf9bf79344cb93f92e_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i2dc6f4e8be7843d6aaca2adf5f4c6884_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id158e2e208fe42f6babb0bf2b8d9c0fd_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i0d6271a8a04b419399a0b38f81c5198f_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ie0f44542e8c740659e299accf3ca4908_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ie342e06932cb4eb09ce0c2794ac21c83_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i54877d697b024c418e4690308061e7d5_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i454c26ac3d9f4433aebd4f00ce56ef66_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i367c35eaeba64e7dacfc5f757575d411_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i5d128d2186654d918c38f7fc1d9b358c_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i17fe29849f934c778d329dd2ac540b0f_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i1f484e76b00143c49d1ffb0c04e1aa31_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i62f678821295404c8ddc6c8b0b67d7e2_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i2cc8acfb8b1c4f2eaf54f3edfd2fca61_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i84e77eb97532442da0b8735429da4ecc_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ifc9c4b5754af40009253488e23ef0207_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i69ee586072574a02b0f1bc1f4029919c_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i1197e68d9d604430b8ce3c78e941f5f2_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i0d2698f3fe114fea898dbd1bedfa2f5c_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForwardContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i393a4aa6df064753bb52276e7ee04a5d_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForwardContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i7734e6b3c1704f4d8a988d1a61348a77_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i399b619e02804ea2ba1db1e14f9ab716_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:EUR</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ib1e612626d9f43b0b769e555166d81e3_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:USD</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ifc7f48af9c2b4b2681e9bd3d3af61b12_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iba8a92586e2b4417a662a578f1511b3c_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:CHF</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i850f90a0299d43458bd33796e0371d13_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:USD</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i1ee3b6969d0e47798c3ab0adfa9e44d6_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPercentEuroNotesDueTwoThousandTwentySixMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i3334c66245af46b9a585510eebce55e0_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPercentEuroNotesDueTwoThousandTwentySixMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:EUR</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="if435a46c948846aca4c19571c1f10bc9_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:USD</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPercentEuroNotesDueTwoThousandTwentySixMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="if10b3957b204438a86f3b2309e56842a_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointFiveZeroPercentPoundSterlingNotesDue2026Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i5e8c12261fc243ddbd412fb565f1b116_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointFiveZeroPercentPoundSterlingNotesDue2026Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:GBP</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i603ad1820fef4e8a8f960404cd15b244_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:USD</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointFiveZeroPercentPoundSterlingNotesDue2026Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id9403f32bf014bd1a180b462efe73171_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPercentPoundSterlingNotesDue2029Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iece903822c1c413ba21f23e1a3a8817b_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPercentPoundSterlingNotesDue2029Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:GBP</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="if9749c18ee4d4475925e12e9fb9d6ec4_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:USD</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPercentPoundSterlingNotesDue2029Member</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ia82e4d4dd7624199b0b9823339e7521e_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="idfede3337ef54161bc5bd47fd541f5ef_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="icc5c639f364e45baa662901e97a7de40_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i01d039e9716e4293aacd1732c82a9104_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i429f2cf41442431d854b0802e1818b63_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="if6773803670d44b2ae4b1519c9996aac_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i5c44b32339c742969f187797f4ae3956_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="icb1c3e075c0447c0a8d96118c3b1ccc0_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i53af41683cb14e598e98d0cdd138caeb_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i9a23429c3e7047b1be61aaf1c0cd68ff_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i4dfa001ded2a48d2a902aa13f44f8684_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i3253252da82e4f4cb4e51fe1f6a14b85_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i5d9649b14f6944e6b32f46773afd94df_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i93734d89c57d45e99c00e58787a09f5e_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ifb6251f8399b4dc69935ab1011467098_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="amgn:DerivativeInstrumentNameAxis">amgn:A2030And2021NoteHedgesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i44869b7e4ad641a5bc2667496e4c4b2c_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByLiabilityClassAxis">amgn:LongTermDebtCurrentMaturitiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ia18546e9b5354e3da7193d7dab9c11f3_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByLiabilityClassAxis">amgn:LongTermDebtCurrentMaturitiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i040b7e3625734005983b800042806116_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByLiabilityClassAxis">us-gaap:LongTermDebtMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="if82a04ddb1484b4d9d685c69534d60ee_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:FairValueByLiabilityClassAxis">us-gaap:LongTermDebtMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i189a6a6830c84033985ac2eb0166844f_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i84ce59b928bc4625b81e9ba243566b0b_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i44310cb41e2e4aaabf0dc581c8c2c4ea_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i2b29edf642674757a33b45fcec1cc8b4_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="icc69b7bd76f6439ea5993cfe7cab843b_D20210701-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-07-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i2368706943c748edb9e18c4bf06ef9ad_D20210101-20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-01-01</xbrli:startDate><xbrli:endDate>2021-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ieccef0ffb45a4fdcbd44c752c16e6068_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i503ef52a14c747cb9fab04a1e85b81d1_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="iaef608c4412a4e94ba0fb53cc211b333_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i1da13ce0b09e46ae9200663802380083_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i7c59c26b885d420cbebeaff7c5823719_D20200701-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-07-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="ife3621a3597c4b819c57657a0cacdc1d_D20200101-20200930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2020-01-01</xbrli:startDate><xbrli:endDate>2020-09-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i6967f808be0e42dd8d431bf91fbf8fda_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForwardContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:NondesignatedMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="icf8902c539da490aa8f154995bfad656_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForwardContractsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:NondesignatedMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i3847de63b915449dacb3fe5ac480d2d4_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:OtherCurrentNoncurrentAssetsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i6dd8345dd5db4bef839be567148829c8_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:AccruedLiabilitiesOtherNonCurrentLiabilitiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i66933df39b94465f8542b2c374051858_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:OtherCurrentNoncurrentAssetsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="iae17d6c368384d6081046e9199b88942_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:AccruedLiabilitiesOtherNonCurrentLiabilitiesMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i6dc0acd554d1417d8ee9828564a05a4d_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:OtherCurrentNoncurrentAssetsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="id9f3f0d26a574ed0a5c0ee09137be2a1_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:AccruedLiabilitiesOtherNonCurrentLiabilitiesMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ic5f888563c394d598153a924bfacbca4_I20210930"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-09-30</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i78df11bae6c9411f901b63b66ef4b7d7_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:OtherCurrentNoncurrentAssetsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i03f545cb57bd498bb5e65da04d641b83_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:AccruedLiabilitiesOtherNonCurrentLiabilitiesMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ie0dc252346c94bbc92e44b537f39ccd3_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:OtherCurrentNoncurrentAssetsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i91c7206f80d44590a0419f271b3f7a9e_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:AccruedLiabilitiesOtherNonCurrentLiabilitiesMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i44a11e7c427b47569c640463a3089cf8_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:OtherCurrentNoncurrentAssetsMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="ide90c3477b63435f97b32f9aba190c02_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:AccruedLiabilitiesOtherNonCurrentLiabilitiesMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i76a5a06206924308b632f5ca3c34bd97_I20201231"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2020-12-31</xbrli:instant></xbrli:period></xbrli:context><xbrli:unit id="patent"><xbrli:measure>amgn:patent</xbrli:measure></xbrli:unit><xbrli:context id="i2cc9eff2f67a40c98702116571cdb627_D20210928-20210928"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:LitigationCaseAxis">amgn:OtezlaANDAPatentLitigationMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-09-28</xbrli:startDate><xbrli:endDate>2021-09-28</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="idaf73178159c45d5ba7f7dde88688204_D20211012-20211012"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:SubsequentEventTypeAxis">us-gaap:SubsequentEventMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="srt:LitigationCaseAxis">amgn:OtezlaANDAPatentLitigationMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-10-12</xbrli:startDate><xbrli:endDate>2021-10-12</xbrli:endDate></xbrli:period></xbrli:context><xbrli:unit id="claim"><xbrli:measure>amgn:claim</xbrli:measure></xbrli:unit><xbrli:context id="i7e4af91b19174262910dae2ac9317e09_I20211026"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="srt:LitigationCaseAxis">amgn:NovartisPharmaAGMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:SubsequentEventTypeAxis">us-gaap:SubsequentEventMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-10-26</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="i7b7289e4de274a45a8d257b031b3ad23_D20211019-20211019"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:SubsequentEventTypeAxis">us-gaap:SubsequentEventMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:TeneobioIncMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:startDate>2021-10-19</xbrli:startDate><xbrli:endDate>2021-10-19</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="i83f84ec51bef4ffe9c7bfc9f4c177613_I20211019"><xbrli:entity><xbrli:identifier scheme="http://www.sec.gov/CIK">0000318154</xbrli:identifier><xbrli:segment><xbrldi:explicitMember dimension="us-gaap:SubsequentEventTypeAxis">us-gaap:SubsequentEventMember</xbrldi:explicitMember><xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:TeneobioIncMember</xbrldi:explicitMember></xbrli:segment></xbrli:entity><xbrli:period><xbrli:instant>2021-10-19</xbrli:instant></xbrli:period></xbrli:context></ix:resources></ix:header></div><div id="i0b2dd96150e340208a57faec23ec2da5_1"></div><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:18pt;font-weight:700;line-height:100%">UNITED STATES</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:18pt;font-weight:700;line-height:100%">SECURITIES AND EXCHANGE COMMISSION</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:18pt;font-weight:700;line-height:100%">Washington, D.C. 20549</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:18pt;font-weight:700;line-height:100%">FORM&#160;<ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:DocumentType" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODcy_5098ae13-da97-40d3-ad90-a48852a8e5d7">10-Q</ix:nonNumeric></span></div><div style="margin-top:9pt;text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">(Mark One)</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.853%"><tr><td style="width:1.0%"></td><td style="width:4.756%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:93.044%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Arial Unicode MS',sans-serif;font-size:12pt;font-weight:400;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" format="ixt-sec:boolballotbox" name="dei:DocumentQuarterlyReport" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6MTE1MDBkOGNhMjk2NDkyM2JiMjhlMDg1MGFhZmViOTAvdGFibGVyYW5nZToxMTUwMGQ4Y2EyOTY0OTIzYmIyOGUwODUwYWFmZWI5MF8wLTAtMS0xLTA_b4f7a63f-4a09-4934-ba7f-71d0f4ba271c">&#9745;</ix:nonNumeric></span></td><td colspan="3" style="padding:2px 25.75pt 2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:100%">QUARTERLY REPORT PURSUANT TO SECTION&#160;13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">For the quarterly period ended <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" format="ixt:date-monthname-day-year-en" name="dei:DocumentPeriodEndDate" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xMzE_2726dbc7-e341-4dfe-b3ae-1c1a2e96c08f">September 30, 2021</ix:nonNumeric></span></div><div style="margin-top:3pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">or</span></div><div style="margin-bottom:1pt;text-align:justify;text-indent:22.5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.853%"><tr><td style="width:1.0%"></td><td style="width:4.756%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:93.044%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Arial Unicode MS',sans-serif;font-size:12pt;font-weight:400;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" format="ixt-sec:boolballotbox" name="dei:DocumentTransitionReport" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NDJiNThhM2FmN2JhNGRmMjliYWQzYmZjOWMzNzFjOGUvdGFibGVyYW5nZTo0MmI1OGEzYWY3YmE0ZGYyOWJhZDNiZmM5YzM3MWM4ZV8wLTAtMS0xLTA_47b6984e-317a-4d0b-9107-ecd5ab90b666">&#9744;</ix:nonNumeric></span></td><td colspan="3" style="padding:2px 25.75pt 2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:100%">TRANSITION REPORT PURSUANT TO SECTION&#160;13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934</span></td></tr></table></div><div style="margin-top:4pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Commission File Number: <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:EntityFileNumber" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODc0_d381cec3-e9eb-40eb-a35e-747b999cc1d3">001-37702</ix:nonNumeric> </span></div><div style="margin-top:9pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:24pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:EntityRegistrantName" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODY3_1644b52f-680a-4ff8-ba46-75eae265b7e2">Amgen Inc.</ix:nonNumeric> </span></div><div style="text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(Exact name of registrant as specified in its charter)</span></div><div style="margin-bottom:1pt;text-align:justify;text-indent:22.5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.853%"><tr><td style="width:1.0%"></td><td style="width:48.533%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:2.581%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:46.486%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" format="ixt-sec:stateprovnameen" name="dei:EntityIncorporationStateCountryCode" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6MWNlNWIyMTRkYWNiNGI5YWJkYjA5NDU3NDVjNzNlNTIvdGFibGVyYW5nZToxY2U1YjIxNGRhY2I0YjlhYmRiMDk0NTc0NWM3M2U1Ml8wLTAtMS0xLTA_f4263497-edba-4c3c-a703-0199a24e461b">Delaware</ix:nonNumeric></span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:EntityTaxIdentificationNumber" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6MWNlNWIyMTRkYWNiNGI5YWJkYjA5NDU3NDVjNzNlNTIvdGFibGVyYW5nZToxY2U1YjIxNGRhY2I0YjlhYmRiMDk0NTc0NWM3M2U1Ml8wLTItMS0xLTA_1ed287b7-31d0-467e-a965-882cce569bc3">95-3540776</ix:nonNumeric></span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">(State or other jurisdiction of<br/>incorporation or organization)</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">(I.R.S. Employer<br/>Identification No.)</span></td></tr><tr style="height:15pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:0 1pt"></td></tr><tr style="height:14pt"><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:EntityAddressAddressLine1" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6MWNlNWIyMTRkYWNiNGI5YWJkYjA5NDU3NDVjNzNlNTIvdGFibGVyYW5nZToxY2U1YjIxNGRhY2I0YjlhYmRiMDk0NTc0NWM3M2U1Ml8zLTAtMS0xLTA_08bd9431-d9b1-43be-b6e6-df1e33fce189">One Amgen Center Drive</ix:nonNumeric></span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:EntityAddressPostalZipCode" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6MWNlNWIyMTRkYWNiNGI5YWJkYjA5NDU3NDVjNzNlNTIvdGFibGVyYW5nZToxY2U1YjIxNGRhY2I0YjlhYmRiMDk0NTc0NWM3M2U1Ml8zLTItMS0xLTA_faddb23d-08c4-4492-acbe-63d97e1ae11a">91320-1799</ix:nonNumeric></span></td></tr><tr style="height:14pt"><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:EntityAddressCityOrTown" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6MWNlNWIyMTRkYWNiNGI5YWJkYjA5NDU3NDVjNzNlNTIvdGFibGVyYW5nZToxY2U1YjIxNGRhY2I0YjlhYmRiMDk0NTc0NWM3M2U1Ml80LTAtMS0xLTA_6a5786cc-25b9-4569-9751-ad6c9ac4308a">Thousand Oaks</ix:nonNumeric></span></td><td colspan="3" style="padding:0 1pt"></td></tr><tr style="height:14pt"><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" format="ixt-sec:stateprovnameen" name="dei:EntityAddressStateOrProvince" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6MWNlNWIyMTRkYWNiNGI5YWJkYjA5NDU3NDVjNzNlNTIvdGFibGVyYW5nZToxY2U1YjIxNGRhY2I0YjlhYmRiMDk0NTc0NWM3M2U1Ml81LTAtMS0xLTA_348e16ae-507f-44da-8eb2-a9b4d3fb96af">California</ix:nonNumeric></span></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">(Address of principal executive offices)</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">(Zip Code)</span></td></tr></table></div><div style="margin-top:4pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">(<ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:CityAreaCode" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODY4_42af7afd-fbcd-40b2-ad8f-ad5076b49529">805</ix:nonNumeric>) <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:LocalPhoneNumber" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODY5_1872a273-8fb7-412f-9c18-dd2564d33d13">447-1000</ix:nonNumeric> </span></div><div style="text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(Registrant&#8217;s telephone number, including area code)</span></div><div style="text-align:center;text-indent:22.5pt"><span><br/></span></div><div style="text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Securities registered pursuant to Section 12(b) of the Act: </span></div><div style="margin-bottom:1pt;text-align:center;text-indent:22.5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:89.035%"><tr><td style="width:1.0%"></td><td style="width:42.742%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:14.499%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:39.459%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">Title of each class</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">Trading Symbol(s)</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">Name of each exchange on which registered</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="i0be1039089ac48b9949c7220072783f8_D20210101-20210930" name="dei:Security12bTitle" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8xLTAtMS0xLTA_c7c82290-2911-4168-b52c-96db3934e996">Common stock, $0.0001 par value</ix:nonNumeric></span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="i0be1039089ac48b9949c7220072783f8_D20210101-20210930" name="dei:TradingSymbol" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8xLTEtMS0xLTA_fd9aaf25-a6c0-40bf-928a-ac64d8c8578c">AMGN</ix:nonNumeric></span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="i0be1039089ac48b9949c7220072783f8_D20210101-20210930" format="ixt-sec:exchnameen" name="dei:SecurityExchangeName" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8xLTItMS0xLTA_3482e6ef-9ea0-4d90-b937-b9114eed53c0">The Nasdaq Stock Market LLC</ix:nonNumeric></span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="i7aae778309b84991a0bcd8e16938fcf6_D20210101-20210930" name="dei:Security12bTitle" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8yLTAtMS0xLTA_f7972174-e3b3-4712-84f6-6b6fede80040">1.250% Senior Notes due 2022</ix:nonNumeric></span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="i7aae778309b84991a0bcd8e16938fcf6_D20210101-20210930" name="dei:TradingSymbol" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8yLTEtMS0xLTA_b2ae11ba-f914-4006-a201-99662cca82c4">AMGN22</ix:nonNumeric></span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="i7aae778309b84991a0bcd8e16938fcf6_D20210101-20210930" format="ixt-sec:exchnameen" name="dei:SecurityExchangeName" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8yLTItMS0xLTA_5985b67f-6cb6-4c4d-b1d6-f54cb6d18689">The Nasdaq Stock Market LLC</ix:nonNumeric></span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="if48b7c2672244974ae505e9c06ea1da9_D20210101-20210930" name="dei:Security12bTitle" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8zLTAtMS0xLTA_8a806c17-1a3f-44b0-ab8b-0626dabf4a49">2.00% Senior Notes due 2026</ix:nonNumeric></span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="if48b7c2672244974ae505e9c06ea1da9_D20210101-20210930" name="dei:TradingSymbol" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8zLTEtMS0xLTA_614973cf-0dc2-438e-98dd-e79245cdb9d1">AMGN26</ix:nonNumeric></span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"><ix:nonNumeric contextRef="if48b7c2672244974ae505e9c06ea1da9_D20210101-20210930" format="ixt-sec:exchnameen" name="dei:SecurityExchangeName" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8zLTItMS0xLTA_fb6d0664-2a1a-4003-8f1e-f95efb14ad86">The Nasdaq Stock Market LLC</ix:nonNumeric></span></td></tr></table></div><div style="text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Indicate by check mark whether the registrant (1)&#160;has filed all reports required to be filed by Section&#160;13 or 15(d)&#160;of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2)&#160;has been subject to such filing requirements for the past 90 days.</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">&#160;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:EntityCurrentReportingStatus" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODc1_b06e80d0-1b3f-4339-8d22-31b2dc23dda6">Yes</ix:nonNumeric>&#160;</span><span style="color:#000000;font-family:'Arial Unicode MS',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#9745;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;No&#160;</span><span style="color:#000000;font-family:'Arial Unicode MS',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#9744;</span></div><div style="margin-top:4pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (&#167; 232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files).</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">&#160;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="dei:EntityInteractiveDataCurrent" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODc2_e38573d7-707d-482a-9c50-5d41f843e500">Yes</ix:nonNumeric>&#160;</span><span style="color:#000000;font-family:'Arial Unicode MS',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#9745;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;No&#160;</span><span style="color:#000000;font-family:'Arial Unicode MS',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#9744;</span></div><div style="margin-top:4pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of &#8220;large accelerated filer,&#8221; &#8220;accelerated filer,&#8221; &#8220;smaller reporting company,&#8221; and &#8220;emerging growth company&#8221; in Rule&#160;12b-2 of the Exchange Act.</span></div><div style="margin-bottom:1pt;margin-top:4pt;text-align:justify"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.853%"><tr><td style="width:1.0%"></td><td style="width:29.500%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:2.728%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:29.207%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:2.728%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:29.207%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:2.730%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" format="ixt-sec:entityfilercategoryen" name="dei:EntityFilerCategory" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6M2Y4Mjk2MzgzMGUwNDc4ZWFkNGE3NjdjNzliN2YzYzgvdGFibGVyYW5nZTozZjgyOTYzODMwZTA0NzhlYWQ0YTc2N2M3OWI3ZjNjOF8wLTAtMS0xLTA_1e4c7208-7897-4684-aa47-bf7b4bdee48a">Large accelerated filer</ix:nonNumeric></span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Arial Unicode MS',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#9745;</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accelerated filer</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Arial Unicode MS',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#9744;</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Non-accelerated filer</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Arial Unicode MS',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#9744;</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Smaller&#160;reporting&#160;company</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Arial Unicode MS',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" format="ixt-sec:boolballotbox" name="dei:EntitySmallBusiness" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6M2Y4Mjk2MzgzMGUwNDc4ZWFkNGE3NjdjNzliN2YzYzgvdGFibGVyYW5nZTozZjgyOTYzODMwZTA0NzhlYWQ0YTc2N2M3OWI3ZjNjOF8xLTEtMS0xLTA_a579792c-b6af-465b-971d-9ac121080a94">&#9744;</ix:nonNumeric></span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Emerging&#160;growth&#160;company</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Arial Unicode MS',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" format="ixt-sec:boolballotbox" name="dei:EntityEmergingGrowthCompany" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6M2Y4Mjk2MzgzMGUwNDc4ZWFkNGE3NjdjNzliN2YzYzgvdGFibGVyYW5nZTozZjgyOTYzODMwZTA0NzhlYWQ0YTc2N2M3OWI3ZjNjOF8xLTMtMS0xLTA_9ba691c7-9a63-45a3-9da9-c45b3f0755f0">&#9744;</ix:nonNumeric></span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr></table></div><div style="text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.  </span><span style="color:#000000;font-family:'Arial Unicode MS',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#9744;</span></div><div style="margin-top:4pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Indicate by check mark whether the registrant is a shell company (as defined in Rule&#160;12b-2 of the Exchange Act).</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">&#160;</span></div><div style="margin-top:4pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Yes </span><span style="color:#000000;font-family:'Arial Unicode MS',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" format="ixt-sec:boolballotbox" name="dei:EntityShellCompany" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODcw_6279dec5-86ed-4e6c-bea2-5b2700e52c53">&#9744;</ix:nonNumeric></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">  No&#160;</span><span style="color:#000000;font-family:'Arial Unicode MS',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#9745;</span></div><div style="margin-top:10pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">As of October 28, 2021, the registrant had <ix:nonFraction unitRef="shares" contextRef="id260522a4d634e208edb416383a7443e_I20211028" decimals="0" format="ixt:num-dot-decimal" name="dei:EntityCommonStockSharesOutstanding" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODEw_2c134a1d-cc84-4174-b22a-689e66b99df2">563,265,902</ix:nonFraction></span><span style="color:#ff0000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">shares of common stock, $0.0001 par value, outstanding.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_7"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">AMGEN INC.</span></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">INDEX</span></div><div style="margin-bottom:1pt;text-align:justify;text-indent:22.5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:95.175%"><tr><td style="width:1.0%"></td><td style="width:8.116%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:78.623%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.961%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Page&#160;No.</span></td></tr><tr><td colspan="6" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_10">PART I - FINANCIAL INFORMATION</a></span></div></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_10">1</a></span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Item&#160;1.</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_13">FINANCIAL STATEMENTS</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_13">1</a></span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_16">CONDENSED CONSOLIDATED STATEMENTS OF INCOME</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_16">1</a></span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_19">CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_19">2</a></span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_22">CONDENSED CONSOLIDATED BALANCE SHEETS</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_22">3</a></span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_25">CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS&#8217; EQUITY</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_25">4</a></span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_28">CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_28">6</a></span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_31">NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_31">7</a></span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Item&#160;2.</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_76">MANAGEMENT&#8217;S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_76">30</a></span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Item&#160;3.</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_106">QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_106">42</a></span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Item&#160;4.</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_109">CONTROLS AND PROCEDURES</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_109">42</a></span></div></td></tr><tr><td colspan="6" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_112">PART II - OTHER INFORMATION</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_112">43</a></span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Item&#160;1.</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_115">LEGAL PROCEEDINGS</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_115">43</a></span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Item&#160;1A.</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_118">RISK FACTORS</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_118">43</a></span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Item&#160;2.</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_121">UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_121">50</a></span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Item&#160;6.</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_124">EXHIBITS</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_124">51</a></span></div></td></tr><tr><td colspan="6" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_127">INDEX TO EXHIBITS</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_127">52</a></span></div></td></tr><tr><td colspan="6" style="padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_130">SIGNATURES</a></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="#i0b2dd96150e340208a57faec23ec2da5_130">58</a></span></div></td></tr></table></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">i</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_10"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:120%">PART I &#8212; FINANCIAL INFORMATION</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">&#160;</span></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_13"></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.853%"><tr><td style="width:1.0%"></td><td style="width:9.880%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:87.920%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Item&#160;1.</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">FINANCIAL STATEMENTS</span></td></tr></table></div><div id="i0b2dd96150e340208a57faec23ec2da5_16"></div><div style="margin-top:18pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">AMGEN INC.</span></div><div style="text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">CONDENSED CONSOLIDATED STATEMENTS OF INCOME</span></div><div style="text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">(In millions, except per-share data)</span></div><div style="text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">(Unaudited)</span></div><div style="text-align:center;text-indent:22.5pt"><span><br/></span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:45.829%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.619%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.619%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.619%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.624%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Revenues:</span></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Product sales</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i237db287808149dc88791dd0402e8c8d_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMy0xLTEtMS0w_ff29ea1e-ea60-4f6a-8628-3606bbd07914">6,320</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="icc3aae43096e4ee2941dfecfdc9776ad_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMy0zLTEtMS0w_5c20c93e-45a0-43e1-aad8-369b7e18c3c6">6,104</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3eb445431b634cc6b3e61727cef7b877_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMy01LTEtMS0w_16c8f25e-7b9e-4696-8116-e3fe10888409">18,026</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i556e038dae96477cbe84bc1653ed5883_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMy03LTEtMS0w_533cab51-3c88-4291-849e-212c66973fdb">17,906</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other revenues</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i488eb65c564543e1895d64ea848f40c4_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNC0xLTEtMS0w_29185add-a4c6-49ea-ae8c-145a10a45d76">386</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id0ffdac343f944aaa636865f0a68567e_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNC0zLTEtMS0w_36dab01a-0276-46b5-af94-aad9417b485c">319</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iddf8eed0ade74615b203cae47895e098_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNC01LTEtMS0w_c64cd7a6-5ec6-46b1-9574-3ac1388b7074">1,107</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia3ba4d704ab343159b80e5ecde0bf68b_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNC03LTEtMS0w_82599f48-6b55-4fa9-b5a7-a463434ea4b0">884</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 19pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total revenues</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNS0xLTEtMS0w_b31f25e4-2219-4fb8-aeaa-a67074be9667">6,706</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNS0zLTEtMS0w_76d26fb3-3a06-4d8a-b7f7-8536d4465afe">6,423</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNS01LTEtMS0w_d0faca0a-01ab-416c-ac76-59666dfc7b98">19,133</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNS03LTEtMS0w_e59f4cda-bb20-46b9-b3b3-87095ce5930d">18,790</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Operating expenses:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cost of sales</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CostOfGoodsAndServicesSold" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOC0xLTEtMS0w_7512a45b-dfe7-4df3-8f78-bc4f4307cb8c">1,609</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CostOfGoodsAndServicesSold" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOC0zLTEtMS0w_30704ad1-73a3-4140-9e35-f55e80205e6e">1,561</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CostOfGoodsAndServicesSold" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOC01LTEtMS0w_a2870e92-906b-4aac-ad35-94e773e3cada">4,736</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CostOfGoodsAndServicesSold" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOC03LTEtMS0w_d162c859-e3e3-4335-90f2-9f72acb32d9b">4,562</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Research and development</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOS0xLTEtMS0w_5b1aa03f-7cba-42c6-af35-0b203e732e3c">1,422</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOS0zLTEtMS0w_95f42a84-073c-4742-9ec5-aa82f0817deb">1,062</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOS01LTEtMS0w_29436589-8c4b-4748-b7bd-db1121f2c67a">3,471</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOS03LTEtMS0w_444901cc-a9ed-4af0-b63e-4d1263d99455">2,978</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Acquired in-process research and development</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTAtMS0xLTEtMA_619dbd92-9f7d-450e-850b-847e6f6d0fe3">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTAtMy0xLTEtMA_f1033f78-c365-42c1-8e13-3627c300a547">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTAtNS0xLTEtMA_39afd2c4-419f-4dd1-851d-0b178deb69ae">1,505</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTAtNy0xLTEtMA_ec4b80ce-3138-4d55-882d-936a60e7dfd9">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Selling, general and administrative</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:SellingGeneralAndAdministrativeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTEtMS0xLTEtMA_5c590541-afe8-4403-87e6-5d3b424e415b">1,305</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:SellingGeneralAndAdministrativeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTEtMy0xLTEtMA_0ca0f98b-6730-4907-9027-c999fd5c6e31">1,346</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:SellingGeneralAndAdministrativeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTEtNS0xLTEtMA_edb1b611-75a5-42d9-8965-dc0a7a49f6e4">3,943</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:SellingGeneralAndAdministrativeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTEtNy0xLTEtMA_05fbfad3-902b-4138-8311-55d6e1ad3f6e">3,957</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:OtherGeneralExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTItMS0xLTEtMA_6da49cd1-95ec-4b1e-bbf2-e014d087f8d5">8</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:OtherGeneralExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTItMy0xLTEtMA_3a45fffe-879b-49fb-acbc-4f204991a519">1</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:OtherGeneralExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTItNS0xLTEtMA_abd6f9db-acdb-4c37-883b-75554f6485c1">143</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:OtherGeneralExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTItNy0xLTEtMA_4cf71ccc-8d70-4cd4-b9af-a61c2738725b">162</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 19pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total operating expenses</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CostsAndExpenses" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTMtMS0xLTEtMA_08d16305-1ab2-437e-8653-1ee80bab1469">4,328</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CostsAndExpenses" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTMtMy0xLTEtMA_ae247b7b-84de-408e-8259-3128764beb35">3,970</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CostsAndExpenses" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTMtNS0xLTEtMA_1a5b8aff-f418-40c5-8ac7-724c4d507754">13,798</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CostsAndExpenses" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTMtNy0xLTEtMA_f8db8374-e08a-4102-868e-8cbc135436d2">11,659</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Operating income</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:OperatingIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTUtMS0xLTEtMA_cef5b2e8-7bed-4f11-ae48-4525779c7ecb">2,378</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:OperatingIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTUtMy0xLTEtMA_6d69ae4c-1238-4905-b279-e76f9d64da23">2,453</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:OperatingIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTUtNS0xLTEtMA_17c9b1e3-7874-4f79-958e-187496ccddd6">5,335</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:OperatingIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTUtNy0xLTEtMA_225a927c-a681-47a1-86bc-4ff84ceb57ba">7,131</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income (expense):</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest expense, net</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:InterestExpenseDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTgtMS0xLTEtMA_e905e146-0842-4819-9fd2-1b1f94b8ca02">296</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:InterestExpenseDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTgtMy0xLTEtMA_5f2f6be6-a138-4301-85c6-cad8fd6e850e">302</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:InterestExpenseDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTgtNS0xLTEtMA_63b5be27-febf-4544-867a-d58acb0a4c6c">862</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:InterestExpenseDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTgtNy0xLTEtMA_ef77d121-0960-4a4b-904a-ec3db8c8325e">944</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income, net</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTktMS0xLTEtMA_50f25787-f8b7-4286-9223-104aac7a2f6a">73</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTktMy0xLTEtMA_fc7c6426-e226-4770-a569-b617c3f6a612">55</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTktNS0xLTEtMA_a6b453ed-7e85-4974-b7c2-ea074d62dfe9">97</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTktNy0xLTEtMA_aaa5c8a8-3684-4790-8977-73e23e7a0b08">69</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income before income taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjEtMS0xLTEtMA_032f8411-1800-42b6-9873-3a8b3ab88382">2,155</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjEtMy0xLTEtMA_e3972ed9-e23c-450c-af31-acf2891edad3">2,206</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjEtNS0xLTEtMA_802ee86c-47d4-4c0d-8ba0-0c65caaec3ca">4,570</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjEtNy0xLTEtMA_31941506-162a-43cf-aaaf-b9ec30ee0531">6,256</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Provision for income taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:IncomeTaxExpenseBenefit" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjMtMS0xLTEtMA_10b83845-ca5c-4148-9a2a-a45ff9491c02">271</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:IncomeTaxExpenseBenefit" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjMtMy0xLTEtMA_5ef2bb2e-949f-4937-b927-fc6b4c4a5fd1">185</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:IncomeTaxExpenseBenefit" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjMtNS0xLTEtMA_8c158659-09b5-4ffd-b97b-f22cc921cbe8">576</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:IncomeTaxExpenseBenefit" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjMtNy0xLTEtMA_aafef26c-f993-4715-82b8-d2b82f8e857d">607</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjUtMS0xLTEtMA_016e3109-c6c5-43a8-aef9-d6fc35e593a4">1,884</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjUtMy0xLTEtMA_788e49e3-ba25-4e7f-b871-f0d7c44a78c5">2,021</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjUtNS0xLTEtMA_b2da8217-15ee-4eeb-8789-b03afc4c415c">3,994</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjUtNy0xLTEtMA_fcf5024a-0d1e-41d0-9096-a35d9410c2c6">5,649</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Earnings per share:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Basic</span></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="2" name="us-gaap:EarningsPerShareBasic" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjgtMS0xLTEtMA_af6ca99f-3921-4a2c-906f-b3c95cd914b6">3.32</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="2" name="us-gaap:EarningsPerShareBasic" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjgtMy0xLTEtMA_14a04564-cb13-4b12-b911-f72482494c0d">3.45</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="2" name="us-gaap:EarningsPerShareBasic" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjgtNS0xLTEtMA_38a9a622-df3c-4831-b037-608c9ead27f4">6.98</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="2" name="us-gaap:EarningsPerShareBasic" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjgtNy0xLTEtMA_5e4e15e5-c325-4bb8-a88c-77ef967ca7cd">9.61</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Diluted</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="2" name="us-gaap:EarningsPerShareDiluted" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjktMS0xLTEtMA_10aa7977-4fef-4802-9668-0cba122ea879">3.31</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="2" name="us-gaap:EarningsPerShareDiluted" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjktMy0xLTEtMA_1d96efe5-e572-40cd-9999-f84804a5619a">3.43</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="2" name="us-gaap:EarningsPerShareDiluted" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjktNS0xLTEtMA_52c2d3a3-8e19-4934-9ce8-2c7d1d6090cc">6.93</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="2" name="us-gaap:EarningsPerShareDiluted" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjktNy0xLTEtMA_3b864ea6-7687-475f-89e8-f6a21b6ce569">9.54</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Shares used in calculation of earnings per share:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Basic</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:WeightedAverageNumberOfSharesOutstandingBasic" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzItMS0xLTEtMA_ad16d9f0-7086-44b4-bf05-42784325bfe0">567</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:WeightedAverageNumberOfSharesOutstandingBasic" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzItMy0xLTEtMA_f477fb3f-36cb-4542-9b45-b8bbee5bbc62">585</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:WeightedAverageNumberOfSharesOutstandingBasic" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzItNS0xLTEtMA_1a5d64eb-10c8-4adc-b514-2493ff0ce933">572</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:WeightedAverageNumberOfSharesOutstandingBasic" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzItNy0xLTEtMA_c3d376fa-eb20-4afb-b3dd-986288434de2">588</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Diluted</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzMtMS0xLTEtMA_cbc5ed98-d146-498c-b176-7d5a7ea6f7e4">570</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzMtMy0xLTEtMA_e818a9de-fb1e-4571-a318-31fab4bbb5e6">589</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzMtNS0xLTEtMA_c6a05d1d-ce89-416c-97ab-6af2629ac788">576</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzMtNy0xLTEtMA_a967d968-04d4-4628-9d98-fbd3b0b8e29d">592</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span><br/></span></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">See accompanying notes.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">1</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_19"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">AMGEN INC.</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">(In millions)</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">(Unaudited)</span></div><div style="text-align:center"><span><br/></span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:45.829%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.619%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.619%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.619%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.624%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfMi0xLTEtMS0w_e3da7c8d-ac98-4e86-9fb9-e0024d20494d">1,884</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfMi0zLTEtMS0w_1ff34e75-a045-439a-a1f9-6e33b6cc1d0b">2,021</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfMi01LTEtMS0w_cdf928ff-1c82-44ca-80ef-02671f90d69a">3,994</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfMi03LTEtMS0w_036cba6f-8fd2-4bec-8054-1fd73d635bcc">5,649</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other comprehensive income (loss), net of reclassification adjustments and taxes:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(Losses) gains on foreign currency translation</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNC0xLTEtMS0w_11ea642d-7bcd-478c-8305-45299f16e581">35</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNC0zLTEtMS0w_1785c386-69d5-4ee1-96f8-f52825ea9641">14</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNC01LTEtMS0w_de9b864b-2379-496b-9542-80fb930f2cf2">60</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNC03LTEtMS0w_8c3f0bcb-f4df-488b-8b34-9d648971376d">41</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Gains (losses) on cash flow hedges</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNS0xLTEtMS0w_36c5334f-0f6b-4c3e-ba58-2b136d1250c6">99</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNS0zLTEtMS0w_72bbe74a-8b42-445c-89e7-43014f8f4e4e">128</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNS01LTEtMS0w_15abf3ee-19d0-40bc-bbab-af97e98dc240">241</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNS03LTEtMS0w_c2c4d810-1f8a-4ffa-844f-2df599a035bc">305</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(Losses) gains on available-for-sale securities</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNi0xLTEtMS0w_3bf8de49-872e-42af-9418-b73118a9e9cf">1</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNi0zLTEtMS0w_d817164a-6184-4b29-8d14-f226203076fe">1</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNi01LTEtMS0w_d6d0c4d3-85e5-4298-a8d5-68446e4c06d4">1</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNi03LTEtMS0w_c526f443-3519-4722-a881-16f7d143a654">20</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" sign="-" name="amgn:OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNy0xLTEtMS0w_df02dd81-165c-422f-a6d1-d5dff7ce0fdb">3</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" sign="-" name="amgn:OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNy0zLTEtMS0w_47637a9a-3f05-4b42-8e3b-02e8f87d5157">7</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" sign="-" name="amgn:OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNy01LTEtMS0w_90eef492-3b49-4d08-9e8c-16f03cd463c1">3</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" sign="-" name="amgn:OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNy03LTEtMS0w_3bbae791-9e58-4585-b0db-2bf4146c649d">9</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other comprehensive income (loss), net of taxes</span></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOC0xLTEtMS0w_6840ff1d-7548-4037-aa7c-52e76c31ed31">60</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOC0zLTEtMS0w_6996e3fe-7253-4a16-bab6-e21c6ff043ee">120</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOC01LTEtMS0w_9d1cc307-9877-4f35-97d2-83123cbece41">177</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOC03LTEtMS0w_07e37f4b-4313-45b8-897a-1f8431fb1be2">375</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Comprehensive income</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ComprehensiveIncomeNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOS0xLTEtMS0w_32a78785-5d36-4318-b488-bb1abd79ec31">1,944</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ComprehensiveIncomeNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOS0zLTEtMS0w_88920489-91c2-4f50-9381-8055ccb2827d">1,901</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ComprehensiveIncomeNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOS01LTEtMS0w_c5a14e3c-6b70-468b-9938-967efc95032e">4,171</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ComprehensiveIncomeNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOS03LTEtMS0w_364e87e7-50ae-4a35-aa41-8bf14ebafb3e">5,274</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span><br/></span></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">See accompanying notes.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">2</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_22"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">AMGEN INC.</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">CONDENSED CONSOLIDATED BALANCE SHEETS</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">(In millions, except per-share data)</span></div><div style="text-align:center"><span><br/></span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:68.929%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:13.519%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:13.522%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">(Unaudited)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="12" style="background-color:#cceeff;padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">ASSETS</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Current assets:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash and cash equivalents</span></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CashAndCashEquivalentsAtCarryingValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNC0xLTEtMS0w_38b55c79-39df-4f47-aa29-585e80705ecd">11,969</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CashAndCashEquivalentsAtCarryingValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNC0zLTEtMS0w_38692a39-f473-4577-88d9-7507ec510443">6,266</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Marketable securities</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" name="us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNS0xLTEtMS0w_61add535-189d-4fb5-a60d-bb6c41c50406">952</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNS0zLTEtMS0w_58f8ad69-b851-4976-b87f-a7d3353cd1dd">4,381</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Trade receivables, net</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AccountsReceivableNetCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNi0xLTEtMS0w_2b2a1110-275f-4f1b-b518-9ab4e62c47d3">4,765</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AccountsReceivableNetCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNi0zLTEtMS0w_1cce1e8e-113e-4131-9cf3-6dd57326ef21">4,525</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Inventories</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:InventoryNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNy0xLTEtMS0w_d46b3cf8-e476-4242-900a-297cd92fc47f">4,152</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:InventoryNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNy0zLTEtMS0w_871a5322-7542-4e6f-9fc0-80deae96bde4">3,893</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:OtherAssetsCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfOC0xLTEtMS0w_c8dc15bc-186e-4383-a6b5-e447c97c93eb">2,542</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:OtherAssetsCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfOC0zLTEtMS0w_923cc3f1-d034-46d4-bd3c-15136e0f1548">2,079</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 19pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total current assets</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AssetsCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfOS0xLTEtMS0w_dadc3666-4bd4-4cc6-b5f6-204801bb714a">24,380</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AssetsCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfOS0zLTEtMS0w_611c5216-0dcc-4b59-aef0-bb1907ff66ba">21,144</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Property, plant and equipment, net</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:PropertyPlantAndEquipmentNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTEtMS0xLTEtMA_f96e452d-d9d9-44a5-81e6-c01317eadf34">4,982</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:PropertyPlantAndEquipmentNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTEtMy0xLTEtMA_be08ef93-7ac9-4086-aabd-a49d21a90dcc">4,889</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Intangible assets, net</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:IntangibleAssetsNetExcludingGoodwill" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTItMS0xLTEtMA_ee9e8019-162d-4205-bcb8-0252c385d70a">14,659</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:IntangibleAssetsNetExcludingGoodwill" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTItMy0xLTEtMA_d36f4fce-0b4c-4cea-a773-7e7148d9394a">16,587</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Goodwill</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:Goodwill" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTMtMS0xLTEtMA_16385a6c-ba2c-47e9-b20f-f2505c6c0f53">14,665</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:Goodwill" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTMtMy0xLTEtMA_ff3b5dee-19c9-48c4-9931-1e115180c602">14,689</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other noncurrent assets</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:OtherAssetsNoncurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTQtMS0xLTEtMA_ba580bea-1d79-43a9-bf95-51c67da43524">6,307</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:OtherAssetsNoncurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTQtMy0xLTEtMA_a343e2bb-137c-4b4b-ae3c-d3c71e233f54">5,639</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total assets</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:Assets" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTUtMS0xLTEtMA_18a84c68-a2e0-4130-907a-664a8419e72b">64,993</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:Assets" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTUtMy0xLTEtMA_9f796a69-9fa9-498d-a832-1e4916064ce5">62,948</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td></tr><tr><td colspan="12" style="background-color:#ffffff;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">LIABILITIES AND STOCKHOLDERS&#8217; EQUITY</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Current liabilities:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accounts payable</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AccountsPayableCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTktMS0xLTEtMA_628ba315-7186-4c5c-89c0-7c7790989413">1,171</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AccountsPayableCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTktMy0xLTEtMA_e9b2a729-9fb0-4819-9f0f-f745093e1cf4">1,421</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AccruedLiabilitiesCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjAtMS0xLTEtMA_dec26657-8bc4-4da0-82c4-37da405bde42">9,383</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AccruedLiabilitiesCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjAtMy0xLTEtMA_8a31aac8-8d1d-489a-bf0c-b98c2001bcf2">10,141</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Current portion of long-term debt</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:LongTermDebtCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjEtMS0xLTEtMA_c0a3143e-c4d9-4e16-b5c9-2cbbbec6710f">4,288</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" name="us-gaap:LongTermDebtCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjEtMy0xLTEtMA_8eed8da4-c848-429d-b4b9-4f23c0831c7c">91</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 19pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total current liabilities</span></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:LiabilitiesCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjItMS0xLTEtMA_339a9d28-90e0-41e7-af46-5ba41d5ff315">14,842</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:LiabilitiesCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjItMy0xLTEtMA_8c861cbb-4566-46f2-9de8-8f80640200ec">11,653</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Long-term debt</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:LongTermDebtNoncurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjQtMS0xLTEtMA_f8a656b5-9c8f-4a72-8b0c-1bbbc298964c">33,291</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:LongTermDebtNoncurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjQtMy0xLTEtMA_db958e75-5761-4c96-bff1-38cb3ebe9e04">32,895</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Long-term tax liabilities</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:LiabilityForUncertainTaxPositionsNoncurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjUtMS0xLTEtMA_b7444edb-6aae-454a-a80f-8f47156e818b">6,483</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:LiabilityForUncertainTaxPositionsNoncurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjUtMy0xLTEtMA_4033155d-59bb-4ff3-8f2f-cbd3cabd36df">6,968</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other noncurrent liabilities</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:OtherLiabilitiesNoncurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjYtMS0xLTEtMA_03c505e2-133d-49ea-8f8c-5ae2fa554185">2,160</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:OtherLiabilitiesNoncurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjYtMy0xLTEtMA_c8ff25b3-d10e-4655-9522-c7e0b3e4e9f8">2,023</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Contingencies and commitments</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" xsi:nil="true" name="us-gaap:CommitmentsAndContingencies" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjgtMS0xLTEtMA_8f299b4a-1f6b-4b32-90ba-eb5aad33b413"></ix:nonFraction></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" xsi:nil="true" name="us-gaap:CommitmentsAndContingencies" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjgtMy0xLTEtMA_ee0ffaba-37b0-4a69-9b71-73604e90aeef"></ix:nonFraction></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Stockholders&#8217; equity:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Common stock and additional paid-in capital; $<ix:nonFraction unitRef="usdPerShare" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="INF" name="us-gaap:CommonStockParOrStatedValuePerShare" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMC0xLTEtMC90ZXh0cmVnaW9uOjUzYTE5MGI2NGViMDQxM2Q5MzMxNjZlN2U4NjkzNmEzXzQ5_ddffa4ab-e128-419c-94f3-0196f0dbc161"><ix:nonFraction unitRef="usdPerShare" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="INF" name="us-gaap:CommonStockParOrStatedValuePerShare" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMC0xLTEtMC90ZXh0cmVnaW9uOjUzYTE5MGI2NGViMDQxM2Q5MzMxNjZlN2U4NjkzNmEzXzQ5_dec66248-c364-4409-a559-081228fe4af0">0.0001</ix:nonFraction></ix:nonFraction> par value; <ix:nonFraction unitRef="shares" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-5" format="ixt:num-dot-decimal" name="us-gaap:CommonStockSharesAuthorized" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMC0xLTEtMC90ZXh0cmVnaW9uOjUzYTE5MGI2NGViMDQxM2Q5MzMxNjZlN2U4NjkzNmEzXzYz_700557e7-00d7-49cf-8b2a-62e3a76356fb"><ix:nonFraction unitRef="shares" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-5" format="ixt:num-dot-decimal" name="us-gaap:CommonStockSharesAuthorized" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMC0xLTEtMC90ZXh0cmVnaW9uOjUzYTE5MGI2NGViMDQxM2Q5MzMxNjZlN2U4NjkzNmEzXzYz_8acb803f-00c1-4953-8190-980f2b64a5a8">2,750.0</ix:nonFraction></ix:nonFraction> shares authorized; outstanding&#8212;<ix:nonFraction unitRef="shares" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-5" name="us-gaap:CommonStockSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMC0xLTEtMC90ZXh0cmVnaW9uOjUzYTE5MGI2NGViMDQxM2Q5MzMxNjZlN2U4NjkzNmEzXzk3_3673c112-1438-4863-adb0-d7400e68ec17">565.0</ix:nonFraction> shares in 2021 and <ix:nonFraction unitRef="shares" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-5" name="us-gaap:CommonStockSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMC0xLTEtMC90ZXh0cmVnaW9uOjUzYTE5MGI2NGViMDQxM2Q5MzMxNjZlN2U4NjkzNmEzXzExNw_09c687d0-d45d-4de4-b611-2796f6480bcd">578.3</ix:nonFraction> shares in 2020</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CommonStocksIncludingAdditionalPaidInCapital" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMS0xLTEtMA_07000854-7c12-4e1d-a616-6f53f96f8b4e">31,989</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CommonStocksIncludingAdditionalPaidInCapital" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMy0xLTEtMA_c56f12d6-b22b-45c7-a9b0-0ead682d3b9d">31,802</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accumulated deficit</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:RetainedEarningsAccumulatedDeficit" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzItMS0xLTEtMA_53f25641-def1-458f-aba3-3c3a06d65e41">22,964</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:RetainedEarningsAccumulatedDeficit" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzItMy0xLTEtMA_8d3731e9-6091-4cf2-a554-9a09946cff5c">21,408</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accumulated other comprehensive loss</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" sign="-" name="us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzMtMS0xLTEtMA_16aee6af-9354-4dbf-afcb-7ca9902f4425">808</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" sign="-" name="us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzMtMy0xLTEtMA_de5d90b4-324b-45ee-be23-9f8cb5a2809d">985</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 19pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total stockholders&#8217; equity</span></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzQtMS0xLTEtMA_72c34e55-8b8e-41a1-89eb-671d8173328b">8,217</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzQtMy0xLTEtMA_448f2387-70ec-4242-928c-6bd5d0573175">9,409</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total liabilities and stockholders&#8217; equity</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:LiabilitiesAndStockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzUtMS0xLTEtMA_fcc32715-a9ec-43a3-bc46-9cc0a28852ac">64,993</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:LiabilitiesAndStockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzUtMy0xLTEtMA_42f2ed98-5c5f-4d19-a36f-5ac4f4e28a9a">62,948</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span><br/></span></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">See accompanying notes.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">3</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_25"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">AMGEN INC.</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS&#8217; EQUITY</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">(In millions, except per-share data)</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">(Unaudited)</span></div><div style="text-align:center"><span><br/></span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.561%"><tr><td style="width:1.0%"></td><td style="width:40.162%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.060%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.060%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.060%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.060%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.062%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Number<br/>of&#160;shares<br/>of&#160;common<br/>stock</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Common<br/>stock and<br/>additional<br/>paid-in&#160;capital</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Accumulated<br/>deficit</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Accumulated<br/>other<br/>comprehensive<br/>loss</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of December 31, 2020</span></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i091ea451ee5b401e9a692e47a31d079b_I20201231" decimals="-5" name="us-gaap:CommonStockSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMS0xLTEtMS0w_02d3606d-393f-4ec4-90d6-c30e4d1ce9f6">578.3</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i85eb1be2504f43d5b6b300dc199131eb_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMS0zLTEtMS0w_5c27968c-ea84-4d19-8669-98ea84f08344">31,802</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i8fd3f59d080644dfb1308254046fba14_I20201231" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMS01LTEtMS0w_f6524f96-6e81-4a36-b0e9-86748eae2d9f">21,408</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="iaea9ac2193424d918f03fbf56ef30362_I20201231" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMS03LTEtMS0w_53ac440f-c9d6-4268-82f3-83e28a808365">985</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMS05LTEtMS0w_841908f0-dd19-4bcb-b38e-deb1a3f48085">9,409</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia7cc3209b62b4e859989adf72041bfb0_D20210101-20210331" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMy01LTEtMS0w_2a83d540-1c6b-4245-ad8b-46e81600c1c1">1,646</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMy05LTEtMS0w_48ee226d-b885-4ad4-a6da-9b91851684d0">1,646</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 16.75pt;text-align:left;text-indent:-9pt;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other comprehensive income, net of taxes</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8ff5ee6ed2904950abde3e69e298a888_D20210101-20210331" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNC03LTEtMS0w_cb465528-454e-49a1-a120-d13ff656566c">152</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNC05LTEtMS0w_cabc0571-6237-4e92-b9ec-680d1297c2ec">152</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Dividends declared on common stock ($<ix:nonFraction unitRef="usdPerShare" contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331" decimals="2" name="us-gaap:CommonStockDividendsPerShareDeclared" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNS0wLTEtMS0wL3RleHRyZWdpb246NmI2NjcxOWI2NDEwNGVlNDgxNjg0ODIzNjkxOGU3ZDRfNDE_9109223a-6d0f-4de2-bdcf-4cc4165d1789">1.76</ix:nonFraction> per share)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ia7cc3209b62b4e859989adf72041bfb0_D20210101-20210331" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DividendsCommonStockCash" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNS01LTEtMS0w_d6b13b9e-4205-46db-9588-7d4a7eafdd6c">1,012</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DividendsCommonStockCash" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNS05LTEtMS0w_9b4d8557-c2e8-463d-91d9-6fb8cf931423">1,012</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Issuance of common stock in connection with the Company&#8217;s equity award programs</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i7969d970f6a54e60804bc95280496c8b_D20210101-20210331" decimals="-5" name="us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNi0xLTEtMS0w_112b2527-7d7d-4f84-97f8-b42aab3e3357">0.7</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dcd4eff17124be29dcc8becb0415e77_D20210101-20210331" decimals="-6" name="us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNi0zLTEtMS0w_5894f068-c357-4ff6-b15c-ef294e00bf03">6</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331" decimals="-6" name="us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNi05LTEtMS0w_2448cd8a-a8b4-40c1-8f1b-3170a60b59e7">6</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Stock-based compensation expense</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dcd4eff17124be29dcc8becb0415e77_D20210101-20210331" decimals="-6" name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNy0zLTEtMS0w_bd2a553d-e226-497c-b61e-41d79dea6bda">57</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331" decimals="-6" name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNy05LTEtMS0w_39408182-007a-4096-861f-1cb5817f67ab">57</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Tax impact related to employee stock-based compensation expense</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dcd4eff17124be29dcc8becb0415e77_D20210101-20210331" decimals="-6" sign="-" name="us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfOC0zLTEtMS0w_2e0de5ca-22fc-4d91-8aff-30b3c9e03f96">59</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331" decimals="-6" sign="-" name="us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfOC05LTEtMS0w_9a9dda57-b39a-427f-8949-6595709b50b2">59</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repurchases of common stock</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="shares" contextRef="i7969d970f6a54e60804bc95280496c8b_D20210101-20210331" decimals="-5" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodShares" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfOS0xLTEtMS0w_8aaca0a4-5481-4f36-a186-eadf56f4d458">3.7</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ia7cc3209b62b4e859989adf72041bfb0_D20210101-20210331" decimals="-6" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfOS01LTEtMS0w_3f7ab1a9-aced-4d05-8cc5-305c6cb54e22">865</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331" decimals="-6" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfOS05LTEtMS0w_5466f643-71f7-4a17-b4bf-b250f69f564c">865</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of March 31, 2021</span></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="ib60c8e3ee5494c37bc18cec8bd0c619c_I20210331" decimals="-5" name="us-gaap:CommonStockSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTAtMS0xLTEtMA_55fd3402-fbe0-4a86-8485-d77749adf67b">575.3</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i79a13e6805f34de1abc4d45f73bf3010_I20210331" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTAtMy0xLTEtMA_be263d06-5dc4-4e64-92c1-1252085a9d9d">31,806</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ifd05c4dcf2974888bb7ea94987a2302e_I20210331" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTAtNS0xLTEtMA_45e372f7-607d-4e94-9d81-2add5c83b268">21,639</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i02d7483a082146bca57a490cca649110_I20210331" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTAtNy0xLTEtMA_8957a366-68b8-4ce0-baa9-6021d5b46636">833</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i65ba920729294b6ca0d58b7c3d55da64_I20210331" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTAtOS0xLTEtMA_873c47e9-8c4d-4964-930c-b6efe9927e3d">9,334</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7a34b44a0b684692a8ce01f962435f05_D20210401-20210630" decimals="-6" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTItNS0xLTEtMA_fbf543bf-7003-48ee-a46c-d9cdfeba710a">464</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630" decimals="-6" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTItOS0xLTEtMA_61957c05-a602-4a00-86db-7edb36f99d3f">464</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 16.75pt;text-align:left;text-indent:-9pt;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other comprehensive loss, net of taxes</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ic34d84ceeae14872821180cf4d7c1fc9_D20210401-20210630" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTMtNy0xLTEtMA_42015501-5633-4ddb-8847-047e84db6153">35</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTMtOS0xLTEtMA_efc0a28c-261b-4439-aa9b-794ae78efb15">35</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Issuance of common stock in connection with the Company&#8217;s equity award programs</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="ibcaee6c81e1645c98fc9f7046d1c84b0_D20210401-20210630" decimals="-5" name="us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTUtMS0xLTEtMA_7e5736e8-fa53-477d-93a5-56a8a6f54a59">0.8</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2ed57ff3dbc9401b9e0afd3df0e57952_D20210401-20210630" decimals="-6" name="us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTUtMy0xLTEtMA_b852b89c-ca87-45d3-8f94-ee91ee1f74e4">47</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630" decimals="-6" name="us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTUtOS0xLTEtMA_8801a2b9-fc02-4a59-ad06-8bff0af0c834">47</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Stock-based compensation expense</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2ed57ff3dbc9401b9e0afd3df0e57952_D20210401-20210630" decimals="-6" name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTYtMy0xLTEtMA_9d07ab84-1d18-4a0d-a91d-568ce1327dd5">100</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630" decimals="-6" name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTYtOS0xLTEtMA_aa7fd2c6-957c-4fa1-8240-c2b5d2e6f2a6">100</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Tax impact related to employee stock-based compensation expense</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2ed57ff3dbc9401b9e0afd3df0e57952_D20210401-20210630" decimals="-6" sign="-" name="us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTctMy0xLTEtMA_4c557748-4443-41a1-ba93-d802a3fc2b3e">76</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630" decimals="-6" sign="-" name="us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTctOS0xLTEtMA_c369fa61-b9b4-48a9-bbf9-67012992c94a">76</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repurchases of common stock</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="shares" contextRef="ibcaee6c81e1645c98fc9f7046d1c84b0_D20210401-20210630" decimals="-5" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodShares" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTgtMS0xLTEtMA_0d4278f3-9b0f-4f07-8e92-e1a186f6e676">6.5</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i7a34b44a0b684692a8ce01f962435f05_D20210401-20210630" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTgtNS0xLTEtMA_00dc1319-a58f-4fc8-9f16-0443395c5d13">1,592</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTgtOS0xLTEtMA_dd25a054-471b-41be-814b-aa9835648be4">1,592</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7a34b44a0b684692a8ce01f962435f05_D20210401-20210630" decimals="-6" name="us-gaap:StockholdersEquityOther" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTktNS0xLTEtMA_d7746640-c7f1-4e5d-87cc-b262c923b8f0">5</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630" decimals="-6" name="us-gaap:StockholdersEquityOther" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTktOS0xLTEtMA_61259cd1-95ec-4346-968a-e74ca7a5cd0d">5</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of June 30, 2021</span></div></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="ib91fd46e082e435c8604678dba5c6807_I20210630" decimals="-5" name="us-gaap:CommonStockSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjAtMS0xLTEtMA_59bf37ac-35c2-4504-928f-7dadd3063794">569.6</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3ee32787b0ee44f7835a1897d7ccc133_I20210630" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjAtMy0xLTEtMA_1cc20ef0-3c83-4e3c-8b0f-bdd95728fe45">31,877</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ib9c55bd482c8427c869df819585fe64b_I20210630" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjAtNS0xLTEtMA_27b02754-b190-4268-9721-c6d5cd883602">22,762</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i9d079f6d807e45a8b0ea7b4bf5ca1b1c_I20210630" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjAtNy0xLTEtMA_e2c427f2-e12c-4abd-8027-5c8e0f897853">868</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ibb4ad07750104a41ad551ce7e97f7afe_I20210630" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjAtOS0xLTEtMA_25d678de-bbae-4a1d-acb9-b333c3b08d18">8,247</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i6271ffbf65cf467783eea9a8f4a54fb0_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjItNS0xLTEtMA_841df04b-4906-4c6c-bc4b-1558207f794a">1,884</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjItOS0xLTEtMA_3bcd5da5-95c8-40e0-8387-9856130dbb0b">1,884</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other comprehensive income, net of taxes</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i984e708e2ca94952a077181e38e25d78_D20210701-20210930" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjMtNy0xLTEtMA_69fb9784-08fd-466c-b412-fe2d014432b1">60</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjMtOS0xLTEtMA_619cb7f5-dc49-4e5c-825c-ff9c380ceb01">60</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Dividends declared on common stock ($<ix:nonFraction unitRef="usdPerShare" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="2" name="us-gaap:CommonStockDividendsPerShareDeclared" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjQtMC0xLTEtMC90ZXh0cmVnaW9uOmZhZTNmNmU0YjU5ZjQ5YjBiZTMxZTJlNTMyYTAyZjNlXzQx_cc1e1b10-737f-45a2-a3b6-32d3a51bc32b">1.76</ix:nonFraction> per share)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i6271ffbf65cf467783eea9a8f4a54fb0_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DividendsCommonStockCash" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjQtNS0xLTEtMA_242f7802-922f-4daa-a265-fd6e1f408a3c">1,017</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DividendsCommonStockCash" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjQtOS0xLTEtMA_42e60471-821c-4d03-be8e-9db30194ad6b">1,017</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Issuance of common stock in connection with the Company&#8217;s equity award programs</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i967296e305e04ee0ba9de8194bd5c859_D20210701-20210930" decimals="-5" format="ixt:fixed-zero" name="us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjUtMS0xLTEtMA_f85d447a-ff03-45c9-a47e-df3669fe2e3c">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia9f1d012da3a43b89a1c71ec6c7599ff_D20210701-20210930" decimals="-6" name="us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjUtMy0xLTEtMA_df9cec2e-05cc-4430-89f5-7ae811b29322">9</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjUtOS0xLTEtMA_e9fd6506-4133-49de-a05e-dbb476572308">9</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Stock-based compensation expense</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia9f1d012da3a43b89a1c71ec6c7599ff_D20210701-20210930" decimals="-6" name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjYtMy0xLTEtMA_56a83445-2979-44a5-8df4-f08f796a7945">111</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjYtOS0xLTEtMA_65a7dde2-6b88-4ef4-aefa-af7e8e73974b">111</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Tax impact related to employee stock-based compensation expense</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ia9f1d012da3a43b89a1c71ec6c7599ff_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjctMy0xLTEtMA_aea9b38f-8701-4b3e-87a1-0ec3d3ee0995">8</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjctOS0xLTEtMA_4f7de278-4e80-4f53-91e6-028257e8b030">8</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repurchases of common stock</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="shares" contextRef="i967296e305e04ee0ba9de8194bd5c859_D20210701-20210930" decimals="-5" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodShares" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjgtMS0xLTEtMA_bddb69c6-1f23-4573-9919-8758da4829e2">4.6</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i6271ffbf65cf467783eea9a8f4a54fb0_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjgtNS0xLTEtMA_0ccaa74a-cdec-4100-abbb-23b0492a79fd">1,069</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjgtOS0xLTEtMA_f9c6ed4a-c87b-4393-b449-0f4cfcdc5fc6">1,069</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of September 30, 2021</span></div></td><td colspan="2" style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i326b605172394be1a3158d27be23c5d3_I20210930" decimals="-5" name="us-gaap:CommonStockSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMzAtMS0xLTEtMA_5530e033-7381-4fe8-a56d-37caec0e33bc">565.0</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id005bde0830f48398b26dea00beb0a27_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMzAtMy0xLTEtMA_fa66c90a-bfbd-4d19-87cf-343dcfe422a8">31,989</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i3deeda31d541496fbfdcf359358e2e31_I20210930" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMzAtNS0xLTEtMA_9a02a6d1-84f4-48a9-a8e4-471bdcdc4f1a">22,964</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ic860f31327384ad08f5dbf6d59cdb763_I20210930" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMzAtNy0xLTEtMA_6296c165-604d-4222-92a7-307dc541ee11">808</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMzAtOS0xLTEtMA_04575772-1f0b-4eea-b091-bf2f1f1ed313">8,217</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:8pt;text-indent:22.5pt"><span><br/></span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">4</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="text-align:center"><span><br/></span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">AMGEN INC.</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS&#8217; EQUITY (continued)</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">(In millions, except per-share data)</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">(Unaudited)</span></div><div style="text-align:center"><span><br/></span></div><div style="text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.561%"><tr><td style="width:1.0%"></td><td style="width:40.162%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.060%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.060%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.060%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.060%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.062%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Number<br/>of&#160;shares<br/>of&#160;common<br/>stock</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Common<br/>stock and<br/>additional<br/>paid-in&#160;capital</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Accumulated<br/>deficit</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Accumulated<br/>other<br/>comprehensive<br/>loss</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of December 31, 2019</span></div></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i9383ea8be6554a1fab020c889f98f560_I20191231" decimals="-5" name="us-gaap:CommonStockSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMS0xLTEtMS0w_b0377c35-91ed-439a-a8f8-0efc7863e12e">591.4</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9fa8d9073cbb4a5e8bd57d0450a06268_I20191231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMS0zLTEtMS0w_d0fc4e3f-8ef7-4455-a0b4-18bf233f12b9">31,531</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i27c34688721e4c3eab67f6dfab55e1ea_I20191231" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMS01LTEtMS0w_1de432bd-23e0-4747-9e52-92c3e9b8063c">21,330</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i3b1542b7bb8c42d092dd7b4a59e1c916_I20191231" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMS03LTEtMS0w_b8e8791d-2bf2-4cf3-8d3c-dc183818bbfe">528</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id63942c02328404c8dac62b9840ef120_I20191231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMS05LTEtMS0w_c7acded9-e5b4-4903-aa38-aaed7c266e6a">9,673</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cumulative effect of changes in accounting principles, net of taxes</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="iac88abda0f2a4f44ab3e6e7248813631_I20191231" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMi01LTEtMS0w_822dd258-a0e8-4507-9d72-1741a8a2e9f2">2</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i093220b291f2482d91c2fbc2c9ffff00_I20191231" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMi05LTEtMS0w_0e782a23-b519-49e5-b5ed-0a2592ec897f">2</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic041513a75144cdd9d651b4d92760425_D20200101-20200331" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMy01LTEtMS0w_7c494a36-9c51-440b-b893-eedde139868e">1,825</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMy05LTEtMS0w_0be10005-802b-496c-8858-9c317c052cfc">1,825</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 16.75pt;text-align:left;text-indent:-9pt;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other comprehensive loss, net of taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i1203a51d54b041baa767dda74da28ae7_D20200101-20200331" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNC03LTEtMS0w_e27043e2-8d19-4266-8fc3-298daaec5c02">134</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNC05LTEtMS0w_b4569ea1-bb7c-45d3-ba28-bc7f59c30b57">134</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Dividends declared on common stock ($<ix:nonFraction unitRef="usdPerShare" contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331" decimals="2" name="us-gaap:CommonStockDividendsPerShareDeclared" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNS0wLTEtMS0wL3RleHRyZWdpb246OWM4ZWQ3OGIxNzNmNGJmZmI1MzQ2M2M4Zjk2MGJkMmNfNDE_d3764b02-c491-4a7a-b9a0-5ca8220f5016">1.60</ix:nonFraction> per share)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ic041513a75144cdd9d651b4d92760425_D20200101-20200331" decimals="-6" name="us-gaap:DividendsCommonStockCash" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNS01LTEtMS0w_80441d65-49e0-43bf-bd0a-cbbe69c7251d">938</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331" decimals="-6" name="us-gaap:DividendsCommonStockCash" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNS05LTEtMS0w_237fc524-3e48-4973-9ba5-99e30bc84e34">938</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Issuance of common stock in connection with the Company&#8217;s equity award programs</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i2ce25f9016044114882e77dd2ae1c3db_D20200101-20200331" decimals="-5" name="us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNi0xLTEtMS0w_b15d7e21-2439-4701-9062-d9887da8efe9">0.9</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8d2a343e4cc5455eb9ba7ef31b5fc432_D20200101-20200331" decimals="-6" name="us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNi0zLTEtMS0w_d095a377-d4c9-4129-9154-2de80cdba10c">10</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331" decimals="-6" name="us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNi05LTEtMS0w_0c918ecd-1272-4d56-b0f6-e5708fc601dd">10</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Stock-based compensation expense</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8d2a343e4cc5455eb9ba7ef31b5fc432_D20200101-20200331" decimals="-6" name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNy0zLTEtMS0w_89fc0005-3248-472a-bbc0-856de21115ae">52</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331" decimals="-6" name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNy05LTEtMS0w_c111f44d-e959-415f-9684-e8a7d73b6fae">52</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Tax impact related to employee stock-based compensation expense</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i8d2a343e4cc5455eb9ba7ef31b5fc432_D20200101-20200331" decimals="-6" sign="-" name="us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfOC0zLTEtMS0w_2c71b982-9c64-430a-b855-6d207b8f20ff">68</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331" decimals="-6" sign="-" name="us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfOC05LTEtMS0w_535a63e9-5634-4461-b5cc-b22f4ad0b9cf">68</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repurchases of common stock</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="shares" contextRef="i2ce25f9016044114882e77dd2ae1c3db_D20200101-20200331" decimals="-5" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodShares" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfOS0xLTEtMS0w_c920933d-6842-4b9b-9a69-5161cfadb3f0">4.3</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ic041513a75144cdd9d651b4d92760425_D20200101-20200331" decimals="-6" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfOS01LTEtMS0w_48153983-eaae-4a98-8200-d3064f0beee6">933</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331" decimals="-6" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfOS05LTEtMS0w_e3b4454a-b875-475d-86e5-da5b31cc8e17">933</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of March 31, 2020</span></div></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="ibc414a46e88b4e40a79c00cb9bfd0717_I20200331" decimals="-5" name="us-gaap:CommonStockSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTAtMS0xLTEtMA_629821a8-4c23-413a-a5bc-0eb2a76af587">588.0</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8ff21ac5e59f4e1c9aaf71c8a6427a9b_I20200331" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTAtMy0xLTEtMA_f57dfd3c-ae9b-4fa7-b29f-b91fb8470421">31,525</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ieb7177b91ced43c4bb32d3c71fc60664_I20200331" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTAtNS0xLTEtMA_2fc859c1-85a0-416d-b147-985a7cdabb7a">21,378</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i9ab337ca3f8b490685a1514d21ef0795_I20200331" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTAtNy0xLTEtMA_c5661163-3c68-444d-b8df-25670f9e45e8">662</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i97aafa8c1ca149ab98952ad235869d3d_I20200331" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTAtOS0xLTEtMA_512407ee-7a94-44ae-9af5-029e212217de">9,485</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iad1c7381eead460f9f20a42237bbc0ab_D20200401-20200630" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTItNS0xLTEtMA_0467a147-f5de-4fa7-803b-bf41d9b65385">1,803</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTItOS0xLTEtMA_249bac9c-bd56-4a41-a869-6287f2fe694b">1,803</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 16.75pt;text-align:left;text-indent:-9pt;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other comprehensive loss, net of taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ia9f6aa7d77f443dfb9ccbbf4060d7af0_D20200401-20200630" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTMtNy0xLTEtMA_c9447911-29e1-49ec-8f93-109923bb1799">121</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTMtOS0xLTEtMA_39447008-de74-4d43-8730-edfb4f33da14">121</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Issuance of common stock in connection with the Company&#8217;s equity award programs</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="if8027892520a4ca5bd94f4c5cfcec8a0_D20200401-20200630" decimals="-5" name="us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTUtMS0xLTEtMA_ed32e901-735f-41af-9ed3-3b3f7a259265">1.0</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7896d230ca994182af0336d7fc0f319c_D20200401-20200630" decimals="-6" name="us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTUtMy0xLTEtMA_aaa7407c-68da-49d9-9cc1-4a9c62fc7606">65</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630" decimals="-6" name="us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTUtOS0xLTEtMA_b959a4ac-b113-43d4-b7a4-480cbc3b7780">65</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Stock-based compensation expense</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7896d230ca994182af0336d7fc0f319c_D20200401-20200630" decimals="-6" name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTYtMy0xLTEtMA_c8531d37-e580-4834-9e14-bfc589673e6f">101</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630" decimals="-6" name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTYtOS0xLTEtMA_4b066a1e-1817-4938-9e3b-1647fd6e49d6">101</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Tax impact related to employee stock-based compensation expense</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i7896d230ca994182af0336d7fc0f319c_D20200401-20200630" decimals="-6" sign="-" name="us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTctMy0xLTEtMA_d08b5f4a-3e20-4875-b532-8549b770e12f">81</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630" decimals="-6" sign="-" name="us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTctOS0xLTEtMA_9a1212d6-0914-41f4-9ccf-835b56dadbd9">81</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repurchases of common stock</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="shares" contextRef="if8027892520a4ca5bd94f4c5cfcec8a0_D20200401-20200630" decimals="-5" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodShares" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTgtMS0xLTEtMA_da457d7e-51fc-4d51-ad07-10e9a505d2fa">2.6</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="iad1c7381eead460f9f20a42237bbc0ab_D20200401-20200630" decimals="-6" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTgtNS0xLTEtMA_08d23eee-694d-4394-adec-cb53e20b4bb4">591</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630" decimals="-6" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTgtOS0xLTEtMA_eed53ef5-ceb2-4276-9003-a6920d2d4da9">591</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="iad1c7381eead460f9f20a42237bbc0ab_D20200401-20200630" decimals="-6" sign="-" name="us-gaap:StockholdersEquityOther" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTktNS0xLTEtMA_59480b55-6a89-429f-9e05-fce081b82ab8">2</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630" decimals="-6" sign="-" name="us-gaap:StockholdersEquityOther" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTktOS0xLTEtMA_831f4f28-5942-438f-8b75-a3358b2e3374">2</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of June 30, 2020</span></div></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="ia393209bc348462397965e66e877a084_I20200630" decimals="-5" name="us-gaap:CommonStockSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjAtMS0xLTEtMA_b1036765-4f79-4100-bb0e-d9bf08b0d7e3">586.4</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8a3527abf717402c896edf9e49b60c2b_I20200630" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjAtMy0xLTEtMA_87e6e9f8-fac8-4a29-95cb-616fbbeffe18">31,610</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i9c61b9be9ad3458088feb12ba9d330d6_I20200630" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjAtNS0xLTEtMA_0ac1b8cf-40e7-4503-8090-bdbfca88d0dc">20,168</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ib5bc8ed5ffb54e45bdec39111af0f8d5_I20200630" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjAtNy0xLTEtMA_6841c96b-ccd0-4ef2-9717-6c5de67879cd">783</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i0d016fa4aa4b4b0b8d61f8f03d2b1ad9_I20200630" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjAtOS0xLTEtMA_d2a39fea-3c7b-467f-b03e-5341fc3bfe21">10,659</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2fdcbf2c5023490a8467f390d0945384_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjItNS0xLTEtMA_68adddae-5206-448a-97b5-448461bf2714">2,021</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjItOS0xLTEtMA_22d1face-27a8-4f93-bbb9-3b4f54e9d62a">2,021</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 16.75pt;text-align:left;text-indent:-9pt;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other comprehensive loss, net of taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ia0027870c8424e858af8516bb7a32d5b_D20200701-20200930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjMtNy0xLTEtMA_0538b09e-e3b1-479c-929e-7f2a62399cb1">120</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossNetOfTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjMtOS0xLTEtMA_484659b9-f289-4be3-bf01-1e037e109137">120</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Dividends declared on common stock ($<ix:nonFraction unitRef="usdPerShare" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="2" name="us-gaap:CommonStockDividendsPerShareDeclared" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjQtMC0xLTEtMC90ZXh0cmVnaW9uOjBlMDYzYWVmNzhiNTQ1ZWE4MTIwZmQ5NjA4MjJkNWJlXzQw_68398fa7-acb0-45e8-81e6-73c70a844ded">1.60</ix:nonFraction> per share)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2fdcbf2c5023490a8467f390d0945384_D20200701-20200930" decimals="-6" name="us-gaap:DividendsCommonStockCash" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjQtNS0xLTEtMA_4a672290-c819-41e1-bdf5-cfbf6037d937">952</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:DividendsCommonStockCash" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjQtOS0xLTEtMA_f3654aa1-528b-4cfc-884c-f9541aba52d2">952</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Issuance of common stock in connection with the Company&#8217;s equity award programs</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="ia750b0fd2e8d494f82d6c68132072625_D20200701-20200930" decimals="-5" name="us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjUtMS0xLTEtMA_ea43bf4e-f1ff-4923-814f-9d92a7a98300">0.1</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if9b3a6e30225464792dc4e6abbd3a015_D20200701-20200930" decimals="-6" name="us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjUtMy0xLTEtMA_9150c62e-2ced-48f8-ab85-9b5d081844cf">5</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjUtOS0xLTEtMA_b6a26a1a-ca32-4d23-a49b-01da11b5d5e2">5</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Stock-based compensation expense</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if9b3a6e30225464792dc4e6abbd3a015_D20200701-20200930" decimals="-6" name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjYtMy0xLTEtMA_986b0d4f-600c-4bc0-b79d-09457d0ca10e">109</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjYtOS0xLTEtMA_bf963ad2-8e1f-4080-95ea-f19a52a732c0">109</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Tax impact related to employee stock-based compensation expense</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="if9b3a6e30225464792dc4e6abbd3a015_D20200701-20200930" decimals="-6" sign="-" name="us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjctMy0xLTEtMA_c63f6ecc-676f-4f6e-b30c-2daa76b07e77">11</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" sign="-" name="us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjctOS0xLTEtMA_77f1226c-e88a-49ef-a8e2-98c08c8db405">11</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repurchases of common stock</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="shares" contextRef="ia750b0fd2e8d494f82d6c68132072625_D20200701-20200930" decimals="-5" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodShares" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjgtMS0xLTEtMA_197bf668-0d15-4e57-a0df-66aad163a546">3.0</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2fdcbf2c5023490a8467f390d0945384_D20200701-20200930" decimals="-6" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjgtNS0xLTEtMA_ccc9f54c-bc4f-444a-afc1-33e5a9961261">752</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:StockRepurchasedAndRetiredDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjgtOS0xLTEtMA_431ed549-965d-4b88-a7c2-fb35368bc4bf">752</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of September 30, 2020</span></div></td><td colspan="2" style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="id0c6f5eb460b4312bb606fc4ad30a816_I20200930" decimals="-5" name="us-gaap:CommonStockSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjktMS0xLTEtMA_d2502aac-0952-49e0-947a-0aa57b19c214">583.5</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7ca21439af704771b81a4e07e28ca15c_I20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjktMy0xLTEtMA_8786ccf3-afa9-4c8a-85b0-1ee1845c5edf">31,713</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i18ba9dc7e2ca40f5b5ccd5e684f54c7a_I20200930" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjktNS0xLTEtMA_90ba0c75-39a5-444b-9c37-77a34d5cd1e0">19,851</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5368a3d307444f2c801d6b1d0963ec11_I20200930" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjktNy0xLTEtMA_df91f94c-153b-478b-927f-e548efd7427b">903</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1a997bb47af74377a26fb3c2164ec5a6_I20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjktOS0xLTEtMA_e258371b-8609-4625-a9a8-b4d72a0e07d0">10,959</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span><br/></span></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">See accompanying notes.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">5</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_28"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">AMGEN INC.</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">(In millions)</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">(Unaudited)</span></div><div style="text-align:center"><span><br/></span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:68.929%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:13.519%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:13.522%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash flows from operating activities:</span></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMy0xLTEtMS0w_528eb014-e4f7-44a3-a2b6-47d16664455f">3,994</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMy0zLTEtMS0w_d796a6ee-fff0-480a-b7f2-3f1a701546f0">5,649</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Depreciation, amortization and other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DepreciationDepletionAndAmortization" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNC0xLTEtMS0w_29729e64-6408-40f9-9ae0-97510ef23552">2,546</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DepreciationDepletionAndAmortization" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNC0zLTEtMS0w_057a30c0-cbbd-4a6a-8640-3a1f1a8038b8">2,728</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Deferred income taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:DeferredIncomeTaxesAndTaxCredits" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNS0xLTEtMS0w_08c42bad-737f-40bc-8967-c76be62120c7">264</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" sign="-" name="us-gaap:DeferredIncomeTaxesAndTaxCredits" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNS0zLTEtMS0w_6387e396-242f-4fcb-8969-2e7456a8b8bd">339</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Acquired in-process research and development</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNi0xLTEtMS0w_ed974ff0-7cf3-455f-ae2e-8423b794fe25">1,505</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNi0zLTEtMS0w_be3adaaa-55cf-4277-b5f6-72d5b68cd938">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other items, net</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:OtherNoncashIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNy0xLTEtMS0w_ac4c60e0-be85-4dae-bad5-e8325de7851e">187</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" sign="-" name="us-gaap:OtherNoncashIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNy0zLTEtMS0w_5585512e-317b-41ff-bee7-fedb5665250a">270</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Changes in operating assets and liabilities, net of acquisitions:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 19pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Trade receivables, net</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:IncreaseDecreaseInAccountsReceivable" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfOS0xLTEtMS0w_ca57aa33-10cb-4135-88ed-4eb82bea043c">269</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:IncreaseDecreaseInAccountsReceivable" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfOS0zLTEtMS0w_c6ca3694-b604-4d05-ba53-c9bad6269a55">31</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 19pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Inventories</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:IncreaseDecreaseInInventories" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTAtMS0xLTEtMA_9faec344-05a6-4452-b7f6-78a3ecd42190">215</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:IncreaseDecreaseInInventories" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTAtMy0xLTEtMA_75da856b-dafb-407c-86f7-6ce095150444">316</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 19pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other assets</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:IncreaseDecreaseInOtherOperatingAssets" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTEtMS0xLTEtMA_4b868ffc-6b7d-47ab-9ff7-922b9eb5191c">373</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" sign="-" name="us-gaap:IncreaseDecreaseInOtherOperatingAssets" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTEtMy0xLTEtMA_2f4193e6-bd3b-4bd5-a3bf-c331325c53f6">64</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 19pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accounts payable</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:IncreaseDecreaseInAccountsPayable" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTItMS0xLTEtMA_325aa58d-af87-46c4-9161-bb63a2f6c3c9">260</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" sign="-" name="us-gaap:IncreaseDecreaseInAccountsPayable" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTItMy0xLTEtMA_729c4f8e-c96f-44f5-be2a-314a76c910b0">202</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 19pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued income taxes, net</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:IncreaseDecreaseInAccruedIncomeTaxesPayable" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTMtMS0xLTEtMA_2b9e5d76-8901-45cb-901b-10214146fdf4">719</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" sign="-" name="us-gaap:IncreaseDecreaseInAccruedIncomeTaxesPayable" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTMtMy0xLTEtMA_15f2fe9d-88b1-48d2-84ef-287a340d6a96">301</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 19pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Long-term tax liabilities</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="amgn:IncreaseDecreaseInNoncurrentTaxLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTQtMS0xLTEtMA_4af9b816-b11e-4af1-ad64-a64dd7877722">102</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="amgn:IncreaseDecreaseInNoncurrentTaxLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTQtMy0xLTEtMA_44d5654a-5289-4524-8a08-e90435749aba">110</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 19pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other liabilities</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:IncreaseDecreaseInOtherOperatingLiabilities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTUtMS0xLTEtMA_255d1abf-bb07-4c42-8deb-7adfd32e2351">219</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:IncreaseDecreaseInOtherOperatingLiabilities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTUtMy0xLTEtMA_b329c2a1-4523-4be9-9632-89a82f9c74d9">712</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 30.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net cash provided by operating activities</span></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetCashProvidedByUsedInOperatingActivities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTYtMS0xLTEtMA_153068b0-4ef5-44a3-b8cd-9025d1affdf8">6,453</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetCashProvidedByUsedInOperatingActivities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTYtMy0xLTEtMA_cf918b75-0012-4166-b982-b9d05eede1d6">8,344</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash flows from investing activities:</span></td><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash paid for acquisitions, net of cash acquired</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:PaymentsToAcquireBusinessesNetOfCashAcquired" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTgtMS0xLTEtMA_608a82e2-f5a3-466d-80ef-e88ad334a857">1,639</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:PaymentsToAcquireBusinessesNetOfCashAcquired" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTgtMy0xLTEtMA_8c7ff196-f509-494d-ac0f-f0c2b489300a">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Purchases of marketable securities</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:PaymentsToAcquireMarketableSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTktMS0xLTEtMA_6d2111b3-57fb-44dd-8eb3-322b34cc5dc3">8,901</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:PaymentsToAcquireMarketableSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTktMy0xLTEtMA_79a623c2-cded-4ff4-ad91-a309a3143cc8">5,329</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Proceeds from sales of marketable securities</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ProceedsFromSaleOfAvailableForSaleSecuritiesDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjAtMS0xLTEtMA_95774a50-54f1-4617-bfda-768ec2873c5d">4,403</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ProceedsFromSaleOfAvailableForSaleSecuritiesDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjAtMy0xLTEtMA_7dd9ea5a-6a8e-4788-a1d0-52cb7c75af8d">2,597</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Proceeds from maturities of marketable securities</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjEtMS0xLTEtMA_222e56a2-bcc3-4b62-967e-2214e9679168">7,927</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjEtMy0xLTEtMA_f200c10d-70e1-4d74-a05c-0857b61596a8">2,338</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Purchases of property, plant and equipment</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:PaymentsToAcquirePropertyPlantAndEquipment" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjMtMS0xLTEtMA_49fd8c22-6abb-4b96-902b-8306b7974400">593</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:PaymentsToAcquirePropertyPlantAndEquipment" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjMtMy0xLTEtMA_bc467f87-215d-48b5-a3cb-5c0579807515">435</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Purchases of equity method investments</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:PaymentsToAcquireEquityMethodInvestments" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjQtMS0xLTEtMA_f22be5dd-abaa-4618-a789-e9dce6d4482b">154</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:PaymentsToAcquireEquityMethodInvestments" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjQtMy0xLTEtMA_7c5dc45b-baea-4741-8ae9-6e93ebb04bca">3,154</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:PaymentsForProceedsFromOtherInvestingActivities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjUtMS0xLTEtMA_e696c439-cc1e-480d-b8c4-29b756352bbc">80</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:PaymentsForProceedsFromOtherInvestingActivities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjUtMy0xLTEtMA_f6645411-86a0-43da-adc5-f3431834f416">34</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 30.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net cash provided by (used in) investing activities</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:NetCashProvidedByUsedInInvestingActivities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjYtMS0xLTEtMA_c5d829bd-aa33-459d-a88c-7cdc02d1869e">963</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:NetCashProvidedByUsedInInvestingActivities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjYtMy0xLTEtMA_ca5ef050-c636-4b98-92e9-3220700e93f8">4,017</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash flows from financing activities:</span></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net proceeds from issuance of debt</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ProceedsFromIssuanceOfLongTermDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjgtMS0xLTEtMA_e0abfc46-cca4-4a1a-860a-60451a0c53cf">4,946</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:ProceedsFromIssuanceOfLongTermDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjgtMy0xLTEtMA_f3bfb1ec-5608-4d17-8409-791c56bb27e3">8,914</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repayment of debt</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:RepaymentsOfLongTermDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjktMS0xLTEtMA_6ddd4561-a898-416c-9a88-1a9fe130d8ad">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RepaymentsOfLongTermDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjktMy0xLTEtMA_9736462c-0e13-4571-8b92-28dbe57771ba">5,000</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repurchases of common stock</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:PaymentsForRepurchaseOfCommonStock" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzEtMS0xLTEtMA_12fe3aa9-8f6a-40af-a527-eae28be3f1e6">3,532</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:PaymentsForRepurchaseOfCommonStock" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzEtMy0xLTEtMA_4076ff53-e1cf-49b6-bf06-a163958054cd">2,281</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Dividends paid</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:PaymentsOfDividendsCommonStock" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzItMS0xLTEtMA_ac273f95-d044-49f4-b162-a73465522ac4">3,023</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:PaymentsOfDividendsCommonStock" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzItMy0xLTEtMA_dcb04943-28b1-4278-bd43-d5e44e02e9b9">2,823</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:ProceedsFromPaymentsForOtherFinancingActivities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzQtMS0xLTEtMA_6e9472a9-cff6-4932-821e-a9c6132e8ebf">104</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" sign="-" name="us-gaap:ProceedsFromPaymentsForOtherFinancingActivities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzQtMy0xLTEtMA_c74d8258-1663-4659-a6a3-97b85e98ef38">87</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 30.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net cash used in financing activities</span></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:NetCashProvidedByUsedInFinancingActivities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzUtMS0xLTEtMA_52635159-7af3-4651-9122-7a7dc54b238c">1,713</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:NetCashProvidedByUsedInFinancingActivities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzUtMy0xLTEtMA_b6e5a5b1-b336-40f4-99e8-07551d8fe2c8">1,277</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:middle"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Increase in cash and cash equivalents</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:middle"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzYtMS0xLTEtMA_a18dfc5e-b071-4233-a22d-cd68e4d08ca6">5,703</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:middle"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:middle"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzYtMy0xLTEtMA_0f7937b1-6457-49bb-8a7a-1bffbbdb1560">3,050</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:middle"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash and cash equivalents at beginning of period</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzctMS0xLTEtMA_c3f47fcb-a505-416e-a45e-77e805bebd2e">6,266</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id63942c02328404c8dac62b9840ef120_I20191231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzctMy0xLTEtMA_4295d9f0-4d4f-4ec7-b68e-c4624b60f3e1">6,037</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash and cash equivalents at end of period</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzgtMS0xLTEtMA_e2e130a1-d72f-4f54-840e-2ec9bed9a6ed">11,969</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1a997bb47af74377a26fb3c2164ec5a6_I20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzgtMy0xLTEtMA_336f4261-f078-4b67-a3b3-3ad5d4f246f2">9,087</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span><br/></span></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">See accompanying notes.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">6</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_31"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">AMGEN INC.</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">September 30, 2021 </span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">(Unaudited)</span></div><div id="i0b2dd96150e340208a57faec23ec2da5_34"></div><div style="text-align:justify"><span><br/></span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">1. <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:SignificantAccountingPoliciesTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMzI3Mw_0a4fb2e0-9b55-4b26-abe6-0031dc1cd5e0" continuedAt="i600f38b4738d4941b51c43b106f6e638" escape="true">Summary of significant accounting policies</ix:nonNumeric></span></div><ix:continuation id="i600f38b4738d4941b51c43b106f6e638"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="amgn:NatureOfOperationsPolicyTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMzMwNw_6e1570de-d9e5-48ab-94e6-e25ee2cdc46f" escape="true"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Business</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Amgen Inc. (including its subsidiaries, referred to as &#8220;Amgen,&#8221; &#8220;the Company,&#8221; &#8220;we,&#8221; &#8220;our&#8221; or &#8220;us&#8221;) is a global biotechnology pioneer that discovers, develops, manufactures and delivers innovative human therapeutics.&#160;We operate in <ix:nonFraction unitRef="segment" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="INF" format="ixt-sec:numwordsen" name="us-gaap:NumberOfOperatingSegments" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMjUz_efda5004-ea88-467f-a02d-4c63c386cc0c">one</ix:nonFraction> business segment: human therapeutics.</span></div></ix:nonNumeric><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="amgn:BasisOfPresentationPolicyTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMzI2Ng_c836ee22-052a-459e-980b-a71ccdc2ddea" escape="true"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Basis of presentation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The financial information for the three and nine months ended September 30, 2021 and 2020, is unaudited but includes all adjustments (consisting of only normal, recurring adjustments unless otherwise indicated), which Amgen considers necessary for a fair presentation of its condensed consolidated results of operations for those periods. Interim results are not necessarily indicative of results for the full fiscal year.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The condensed consolidated financial statements should be read in conjunction with our consolidated financial statements and the notes thereto contained in our Annual Report on Form 10-K for the year ended December 31, 2020, and with our condensed consolidated financial statements and the notes thereto contained in our Quarterly Reports on Form 10-Q for the periods ended March 31, 2021 and June 30, 2021.</span></div></ix:nonNumeric><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:ConsolidationPolicyTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMzI0OA_cbe75e0b-38e1-439f-a541-92d4a9935dc8" escape="true"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Principles of consolidation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The condensed consolidated financial statements include the accounts of Amgen as well as its majority-owned subsidiaries. We do not have any significant interests in any</span><span style="color:#ff0000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">variable interest entities. All material intercompany transactions and balances have been eliminated in consolidation.</span></div></ix:nonNumeric><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:UseOfEstimates" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMzI3Ng_5ff1e4ae-3881-4239-b692-0a7fea64f95e" escape="true"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Use of estimates</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The preparation of condensed consolidated financial statements in conformity with U.S. generally accepted accounting principles (GAAP) requires management to make estimates and assumptions that affect the amounts reported in the condensed consolidated financial statements and accompanying notes. Actual results may differ from those estimates.</span></div></ix:nonNumeric><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:PropertyPlantAndEquipmentPolicyTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMzI2NA_c42060f4-29e9-4bb4-b866-af4f35a85326" escape="true"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Property, plant and equipment, net</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Property, plant and equipment is recorded at historical cost, net of accumulated depreciation and amortization of $<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMTg5OA_06877cb9-5d99-41e1-ad40-d2ec966fae98">9.2</ix:nonFraction>&#160;billion and $<ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMTkwNQ_70d663f1-b9f3-478e-8c03-5b1cab971fc2">9.0</ix:nonFraction> billion as of September 30, 2021 and December 31, 2020, respectively.</span></div></ix:nonNumeric><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:NewAccountingPronouncementsPolicyPolicyTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMzI5Nw_806c23a9-af67-4694-8225-09e3e561cb49" escape="true"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Recent accounting pronouncements</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In March 2020, the Financial Accounting Standards Board (FASB) issued a new accounting standard to ease the financial reporting burdens caused by the expected market transition from the London Interbank Offered Rate (LIBOR) and other interbank offered rates to alternative reference rates, commonly referred to as reference rate reform. The new standard provides temporary optional expedients and exceptions to current GAAP guidance on contract modifications and hedge accounting. Specifically, a modification to transition to an alternative reference rate is treated as an event that does not require contract remeasurement or reassessment of a previous accounting treatment. Moreover, for all types of hedging relationships, an entity is permitted to change the reference rate without having to dedesignate the hedging relationship. The standard is generally effective for all contract modifications made and hedging relationships evaluated through December 31, 2022. In January 2021, the FASB issued a new accounting standard to expand on the scope of the original March 2020 standard to include derivative instruments on discounting transactions. We are currently evaluating the impacts that the two standards will have on our condensed consolidated financial statements.</span></div></ix:nonNumeric></ix:continuation><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">7</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_37"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;margin-top:3pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">2. <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:BusinessCombinationDisclosureTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNy9mcmFnOmM1MzFiN2NmODEzZDRlNGNhZmEyMGNhMjA1MDNmNGM0L3RleHRyZWdpb246YzUzMWI3Y2Y4MTNkNGU0Y2FmYTIwY2EyMDUwM2Y0YzRfOTUy_332e78c6-385f-4e66-8731-bfad928bfa55" continuedAt="i1c1e9670128c45e3bf7be1f2dca52f4a" escape="true">Acquisitions</ix:nonNumeric></span></div><ix:continuation id="i1c1e9670128c45e3bf7be1f2dca52f4a"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On April 16, 2021, Amgen completed its acquisition of Five Prime Therapeutics, Inc. (Five Prime) for total consideration of $<ix:nonFraction unitRef="usd" contextRef="i65976c78d95c49118311d26eb3256876_D20210416-20210416" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:PaymentsToAcquireBusinessesNetOfCashAcquired" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNy9mcmFnOmM1MzFiN2NmODEzZDRlNGNhZmEyMGNhMjA1MDNmNGM0L3RleHRyZWdpb246YzUzMWI3Y2Y4MTNkNGU0Y2FmYTIwY2EyMDUwM2Y0YzRfMTM2_93ee1082-b43b-42d4-9198-0db6a3bd7ea9">1.6</ix:nonFraction>&#160;billion, net of cash acquired. The purchase price was funded with cash on hand. This transaction was accounted for as an asset acquisition because substantially all the value of the assets acquired was concentrated in the intellectual property rights of bemarituzumab, a phase 3 trial-ready, first-in-class program for gastric cancer. Five Prime&#8217;s operations have been included in our condensed consolidated financial statements commencing after the acquisition date.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We allocated the consideration to acquire Five Prime to: the bemarituzumab in-process research and development (IPR&amp;D) program of $<ix:nonFraction unitRef="usd" contextRef="i65976c78d95c49118311d26eb3256876_D20210416-20210416" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNy9mcmFnOmM1MzFiN2NmODEzZDRlNGNhZmEyMGNhMjA1MDNmNGM0L3RleHRyZWdpb246YzUzMWI3Y2Y4MTNkNGU0Y2FmYTIwY2EyMDUwM2Y0YzRfNzI5_cc433a15-2bfc-401a-9eb9-7ecc489052b2">1.5</ix:nonFraction>&#160;billion, which was expensed immediately in Acquired IPR&amp;D expense in the Condensed Consolidated Statements of Income; deferred tax assets of $<ix:nonFraction unitRef="usd" contextRef="ifd83e7d77b084c5d854ddc58d39a3bcf_I20210416" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNy9mcmFnOmM1MzFiN2NmODEzZDRlNGNhZmEyMGNhMjA1MDNmNGM0L3RleHRyZWdpb246YzUzMWI3Y2Y4MTNkNGU0Y2FmYTIwY2EyMDUwM2Y0YzRfODY1_b6675964-a014-4f96-9b2c-2939eb6b5018">177</ix:nonFraction>&#160;million; and other net liabilities of $<ix:nonFraction unitRef="usd" contextRef="ifd83e7d77b084c5d854ddc58d39a3bcf_I20210416" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNy9mcmFnOmM1MzFiN2NmODEzZDRlNGNhZmEyMGNhMjA1MDNmNGM0L3RleHRyZWdpb246YzUzMWI3Y2Y4MTNkNGU0Y2FmYTIwY2EyMDUwM2Y0YzRfODk4_c9c0156c-dab0-4f66-8ca2-fb048d07eb0d">47</ix:nonFraction>&#160;million. The acquired IPR&amp;D expense was not tax deductible.</span></div></ix:continuation><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">8</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_40"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;margin-top:3pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">3. <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:RevenueFromContractWithCustomerTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RleHRyZWdpb246NTQyN2ZkOWM3M2FhNDE2MDkzNWUwZjYzYTM2M2QyYTJfNTc0_370eaf6e-b1cb-4907-88cc-ea4a8953d073" continuedAt="iaff41e6a73554a0988e0c675d9e7bf0b" escape="true">Revenues</ix:nonNumeric></span></div><ix:continuation id="iaff41e6a73554a0988e0c675d9e7bf0b" continuedAt="i08c9f75261cb454b8c7f35c7c905b761"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We operate in <ix:nonFraction unitRef="segment" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="INF" format="ixt-sec:numwordsen" name="us-gaap:NumberOfOperatingSegments" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RleHRyZWdpb246NTQyN2ZkOWM3M2FhNDE2MDkzNWUwZjYzYTM2M2QyYTJfMjY_d2f6f122-54b4-4c80-b6bb-3931de2aab68">one</ix:nonFraction> business segment: human therapeutics. Therefore, results of our operations are reported on a consolidated basis for purposes of segment reporting, consistent with internal management reporting. Revenues by product and by geographic area, based on customers&#8217; locations, are presented below. The majority of rest-of-world (ROW) revenues relates to products sold in Europe.</span></div><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:DisaggregationOfRevenueTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RleHRyZWdpb246NTQyN2ZkOWM3M2FhNDE2MDkzNWUwZjYzYTM2M2QyYTJfNTcy_dfd9d37f-0116-43c5-9d0b-9cefe5e1583f" continuedAt="i96ff44d7f7bb416e8228a481b65d7aac" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Revenues were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:32.818%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.133%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.133%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.823%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.133%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.133%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.133%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.144%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="33" style="border-bottom:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended September 30,</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S.</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">ROW</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S.</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">ROW</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Enbrel</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(etanercept)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic6cdb58f08f6497e9571e255839b182e_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMy0yLTEtMS0w_a561ef62-ed96-4bd9-9cc5-f742d187ab32">1,263</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="idb19909eae6245c0b192e54299cbf115_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMy00LTEtMS0w_8b1f182c-93ff-4d5d-ae77-120db0bdf298">26</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iff8d101adf4b402f8cf46cf5dcd93486_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMy02LTEtMS0w_dc78982f-4e0a-45e3-8af4-5ba7d7405767">1,289</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8c7cf69cd4834e9c85f4459b2de8d602_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMy04LTEtMS0w_1f157e3e-41d7-4fe6-940a-a9f279aaa72e">1,289</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i881925882b374e84accf889451f21493_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMy0xMC0xLTEtMA_3520cc13-abfc-4ac4-83a8-7785fcbc6303">36</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3580e2b0cb29470bad2033dc2b011286_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMy0xMi0xLTEtMA_1a962bd1-8391-41ca-8891-9417af9f48f3">1,325</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (denosumab)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i928ab90d0db745ea81bb2a93d965f16e_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNC0yLTEtMS0w_873e8465-16dc-45a0-b5ad-6e2912ad709d">530</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia5bb4cc11d6c483d8309a8c954255a3c_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNC00LTEtMS0w_fc4e2f4f-a19d-46ba-894d-1257fbc617c0">273</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5ad790cbfd31467bb8daa208b16d7e6e_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNC02LTEtMS0w_339ef089-0e1e-4662-9f09-3bc00e7f81e2">803</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iee4b7620a6e94b15a0ee2efa21046c26_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNC04LTEtMS0w_14eaa7fb-e88d-41e9-b799-5bdece1a7536">478</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic41a377f5b39468994f26d4f4fb0aa51_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNC0xMC0xLTEtMA_f87b722c-74ca-49a2-8296-8ec498ad5201">223</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9e2067897ce84b959d0906d105ab21e8_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNC0xMi0xLTEtMA_d1d1ef08-a3d6-4552-96f1-80efbae1241b">701</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(apremilast)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ica2c1ae056384bd5808311f2c76005bd_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNS0yLTEtMS0w_dbb652c1-e420-4c51-8c78-791c40d7b862">495</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1e4fbb00243e4f62ba164169062363bd_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNS00LTEtMS0w_cfb60a81-f2dd-49c3-be3f-9a185a727b67">114</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id03562c57df94c4695307d990b6d880d_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNS02LTEtMS0w_f2903dc8-661f-474a-ac39-b598fdf3c286">609</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie59bcfe33b8147c0b1c58739ec6f4501_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNS04LTEtMS0w_1b45624b-6794-435d-b4d3-d7a4b10ccea3">439</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7d0db737d136412cabc053873e3c0f55_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNS0xMC0xLTEtMA_7c7ec947-1867-4d96-b291-ea163ab10676">99</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i997de67b4d8041fd92aa65650ae56646_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNS0xMi0xLTEtMA_c572afa4-9934-402b-a98c-ce0631ad5f77">538</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (denosumab)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i6be8feef3fae4c3ab81bc1a648281c8c_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi0yLTEtMS00MTE2Nw_77c5aecd-da84-46d0-ab54-70b25516d39d">372</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ib1e795008cb04855b4f4ada989eec622_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi00LTEtMS00MTE2Nw_3133836a-d541-48c6-ba53-a5f02530de85">145</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7fb5d6e70e864ca9a24965da716a59f9_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi02LTEtMS00MTE2Nw_a49dd798-ede4-4bee-865d-561ce8d3c619">517</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8f5c65603d3b495a97c04bb49c2930c7_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi04LTEtMS00MTE2Nw_e99be74a-9872-46b9-af06-6208a31253ed">363</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if2f93bdf48274317b1da0bbaad739897_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi0xMC0xLTEtNDExNjc_f2bb95b3-0ec6-4982-a71f-361eeafc185a">118</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i6d80e26ad167494498b23e0ca5271458_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi0xMi0xLTEtNDExNjc_fe991410-454d-4cd6-a65c-b20ad0f4c368">481</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(pegfilgrastim)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i17187759eba94aadb3d31a3510ebf19e_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi0yLTEtMS0w_5442f293-8b65-4935-8388-e9a2a4a8837a">360</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i641be115cab64df981d42cdd9261ce71_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi00LTEtMS0w_73cf3518-7959-4ea0-917e-d00c3b93db17">55</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i368f295d54bd4525bb8eb6714d3d0066_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi02LTEtMS0w_98eb94ca-231f-4d75-8224-69aadad33060">415</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="icf361ee93a5a459fb961382bfdaab897_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi04LTEtMS0w_9f71d935-e7d0-4df8-8070-e4ba0eddaf59">484</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iae3f58a4ca5c4ee6b7a5efa557d3239e_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi0xMC0xLTEtMA_3dfd6920-b8c7-4236-9504-5aac6f14a3a1">71</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i89c0f0d97cef4bd6b1184caf279f571a_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi0xMi0xLTEtMA_6fb9878b-7e53-4857-81cb-49d978ddbc9c">555</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(darbepoetin alfa)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i739f696b931d4702b3df5ae6ca746716_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOC0yLTEtMS0w_69e5f02e-8ab5-451c-92ef-91ffd61b1e2d">149</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if968e6327f794c59a9ba65fc3208a8f6_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOC00LTEtMS0w_c1f8f87c-ad0f-4b88-9393-715a8322bb17">247</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic9d9abb7215c47c2a1aca1be0668980f_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOC02LTEtMS0w_bc9f5b44-92e2-4768-af0b-26f866c7226a">396</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5b3ef1a8e7f545cfa45814ef6cc1e9ef_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOC04LTEtMS0w_9690b1e8-5649-4ad1-8093-c2507a856143">158</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i65474b7854d64aadbcea001bcca67fcc_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOC0xMC0xLTEtMA_9905eafc-6ed5-4a5b-8fb1-bc80a460269f">226</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id84e814556764ab79f45c36978bd96e4_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOC0xMi0xLTEtMA_953aaef0-0e80-41af-9074-272d9e0ef5f2">384</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(evolocumab)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i39b00b7d625e4f6487ec0db17bdc442d_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOS0yLTEtMS0w_1df4398f-ef0a-49a7-ac99-3062bd8ffedc">139</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i817db5726ac748d4bd491dbef24298e8_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOS00LTEtMS0w_37c2b8a6-bca5-4af5-a74c-74c606323fd6">133</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if48659bf944e4492a4dafa719e7083d0_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOS02LTEtMS0w_7c5b8761-cf6b-4747-929e-a19d503707c0">272</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7b514b2a404649a58ac1b9f9087c9ed6_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOS04LTEtMS0w_ebc7b613-0789-4097-9bd5-9cb99ac411a8">92</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i69c93666703d4eac86caffd587b7db7d_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOS0xMC0xLTEtMA_146205d3-6142-4af6-af71-384613797538">113</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i0dea61c77564492ab39c0a6ee2a71ffb_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOS0xMi0xLTEtMA_dfc12f87-a9d7-42f2-8d85-162ad9ad9720">205</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(carfilzomib)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i643c94b54a124674bdf0a819e67e429b_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTAtMi0xLTEtMA_c8681913-9e91-4175-b5a9-baa6ed28dcc9">198</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i21f6d8435c474c6980866635aeee71e9_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTAtNC0xLTEtMA_bc36699a-cbba-48fa-8dfa-ab6411766938">95</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i0c97db9ff3494e8c8961a94b3979974b_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTAtNi0xLTEtMA_b4c39a63-a743-4a8d-9f28-a1fc8a55c9d4">293</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i36d299d1d5a642cca156e5411c4b4fc8_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTAtOC0xLTEtMA_f08e7698-834b-432e-aee5-03d7331a76fc">173</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ifadfb5ce284249b49c5b541e46f8fd6d_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTAtMTAtMS0xLTA_cfcf768a-dc7b-4272-a936-3a9a0b9fe8d7">87</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ibb9fffae57f44694bf945745287d733a_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTAtMTItMS0xLTA_3d23b444-4040-436b-b4c6-b0a9ae2dea29">260</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other products</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2f0871bad93240bd851a8f0aaa387350_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTEtMi0xLTEtMA_afbbc328-a687-4503-b453-abf59edf2bbb">1,052</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i10acdfdcf69c40c2a0bdc6d3e81fb337_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTEtNC0xLTEtMA_9688a464-b0b7-4cd9-9725-9601688b0bf0">674</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i23817bdf825e4ae1ac3362ea0639d136_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTEtNi0xLTEtMA_b6e5b8ff-7884-4aa4-af05-d10e42d995eb">1,726</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i0beb71107b234faea29110b3fa9d8a98_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTEtOC0xLTEtMA_f8c5d900-ad67-4229-b6ad-10f387e5cce2">1,142</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic81b8501b6db4aee88091da6a3afdf07_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTEtMTAtMS0xLTA_eea2bd1a-6308-431b-a04e-ea2a816ca8d0">513</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if807b6245b86445088eb952987a6b469_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTEtMTItMS0xLTA_e654a972-f8d8-4d3a-865c-b819fdad45fc">1,655</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total product sales</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia3c6be49d4364b1f9f7490f5b324e697_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTItMi0xLTEtMA_9c788d5a-b307-4d9e-82df-09062b90c22e">4,558</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2032ce010c324b94be367952c9e7ba79_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTItNC0xLTEtMA_ff609518-d18b-4c30-9364-c2c58ba7ecf7">1,762</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i237db287808149dc88791dd0402e8c8d_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTItNi0xLTEtMA_07e2dc7d-ccae-4e9b-b244-48e590bbc993">6,320</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8b0da7f54b9d44ec896bac0ef1d0eb58_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTItOC0xLTEtMA_837333e1-b56f-44ad-8364-66b73356d31a">4,618</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i05cbea6753bb40cc89759fbeb6e01550_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTItMTAtMS0xLTA_3108c977-2357-431a-94a2-ee1de3c7a58a">1,486</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="icc3aae43096e4ee2941dfecfdc9776ad_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTItMTItMS0xLTA_68aa43f2-1c2b-45d2-884e-3106ba775070">6,104</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other revenues</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i488eb65c564543e1895d64ea848f40c4_D20210701-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTMtNi0xLTEtMA_29185add-a4c6-49ea-ae8c-145a10a45d76">386</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id0ffdac343f944aaa636865f0a68567e_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTMtMTItMS0xLTA_36dab01a-0276-46b5-af94-aad9417b485c">319</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total revenues</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTQtNi0xLTEtMA_348c9739-fe62-41bb-98e2-ad33dc291ba2">6,706</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTQtMTItMS0xLTA_7ff13a12-b0d0-42c3-836b-7cb434c7cab3">6,423</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="33" style="border-bottom:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended September 30,</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S.</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">ROW</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S.</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">ROW</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">ENBREL</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia48b8184147044458082feb5ea147e49_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTktMi0xLTEtMA_8954affe-fbe3-423f-b816-4124c1a09c16">3,270</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i99ffbf75ddf84e1e9245421a8c01d767_D20210101-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTktNC0xLTEtMA_c4510e0e-1442-496c-b295-36d18ccdbae2">87</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="idab45a332369432d9ebd6f50b96a8f56_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTktNi0xLTEtMA_102d5de0-7bb3-4b3c-8376-b787d68de5bb">3,357</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ica6caa6433a24945a279239a702b2abf_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTktOC0xLTEtMA_b3c838af-8f5f-4521-89c4-f7180cc4efe2">3,619</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic1bb05a1b59b4da5902e961b2a5533a0_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTktMTAtMS0xLTA_9831cf18-3f13-4e05-9245-debff2ad3ea1">105</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7cbcc55bfaff415a96eaa73c996dbb6a_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTktMTItMS0xLTA_3e731624-d05f-41a3-9237-142ec6d216de">3,724</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iaf3073b6b8e349c9b88d3cb4f719e628_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjAtMi0xLTEtMA_0e5d3e25-dfa5-429e-86e7-8c92e73cf90e">1,569</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ib9e71fbc76704655955f107a3a191a9c_D20210101-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjAtNC0xLTEtMA_017390a3-f89d-4294-8c96-a7935281e098">806</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ide3ecdc601c44f8d89456132330e9af2_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjAtNi0xLTEtMA_a8a214da-1acd-46cf-b594-35928f1a7662">2,375</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i17357cd18fe541d0a042e9ee59c93b38_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjAtOC0xLTEtMA_c1fe4ea8-0a9a-40b3-a7e8-c5c80f3c21fd">1,341</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ib3777a2c9f034e97919676bb7754de25_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjAtMTAtMS0xLTA_35d6002e-5f5f-4a09-ab13-449ade21fc82">673</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i6b5f2a9043d945b08ec0167f3cfed9f2_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjAtMTItMS0xLTA_960e28af-0fdf-4f35-a7ae-765877065a15">2,014</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i95957399b3a14e7383788a66404fcbbb_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjEtMi0xLTEtMA_71c15aba-8e9c-4e05-ba7f-45dc025f9b28">1,284</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i78293d5fa71b41ef9cc01a231545bab2_D20210101-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjEtNC0xLTEtMA_c47a4321-c0e9-4bf4-bf1f-53d1520c398b">335</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i195420e0531242db9f936a0127259be3_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjEtNi0xLTEtMA_cb75c058-d9d1-4881-8149-af0fcc8d154a">1,619</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if0fb79f0bfbc4e51b7cb42fd1d71c840_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjEtOC0xLTEtMA_fcf2000b-cc7b-4db5-a7ee-0d32447a1f46">1,280</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i68bf0dc18c0d4ffa9e9a898ff74c54f1_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjEtMTAtMS0xLTA_5ec06311-14c7-4922-ade7-a032dcb5e99f">298</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ibe1bd36ce26a43fe9cb844c7326c4e54_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjEtMTItMS0xLTA_b73ccc46-8b37-4a38-9dbd-912cf3bea94f">1,578</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> </span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7da33cf805a445869662f5abc2106d6d_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItMi0xLTEtNDExNTc_5cafc24c-d0c3-40eb-b409-e6eae599631c">1,061</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia6106c345460401c9e03019b7c080699_D20210101-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItNC0xLTEtNDExNTc_b15a0936-cae3-4f68-83b9-535ad294ee25">412</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i443bd36291d548a0aa9856e73206eac6_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItNi0xLTEtNDExNTc_a58942a0-184b-43d7-8708-9fff02f71ba0">1,473</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id7ca09709e904974a92ad3adb8b9fd77_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItOC0xLTEtNDExNTc_7f9e608b-7653-45c5-9bb6-5ea16cddbfce">1,036</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i98005524cd124b8c966a68f6bdcfb8fc_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItMTAtMS0xLTQxMTU3_6cd8c491-1bf9-4722-8c78-2673b2bffdce">361</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5b4401a3903c4c908d2eb7fe95caad21_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItMTItMS0xLTQxMTU3_52c2c58e-bfd3-4db6-850d-06f33972d3b6">1,397</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3cd61c0be22f4420b7238ce5a6df9130_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItMi0xLTEtMA_a27038ea-44f9-417d-8fcc-adb9adea2083">1,215</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iae6381714cfe468aa29ce147540ec7e9_D20210101-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItNC0xLTEtMA_2a195e2f-2124-485b-8d72-88016c62dee2">168</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i96040b94405a4bd1a72890459e71ee00_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItNi0xLTEtMA_4ea8dbfa-42cb-4f06-ba86-158f2b8188a0">1,383</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iad909099174b42f681a09827cb78f0a7_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItOC0xLTEtMA_81bf638c-49e5-4edd-a09e-bf2c182c65e5">1,538</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9445f98f484747b89af2e9d73ea09d95_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItMTAtMS0xLTA_1257a287-8ecc-4c4b-902d-900be84c0998">219</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ib01fa4a797464e63b788127b5705e442_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItMTItMS0xLTA_5bacfd06-c605-42a9-8f52-556908244ceb">1,757</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i4f38a5540cd04d718fff14e7bd440bf3_D20210101-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjQtMi0xLTEtMA_87d1094a-d347-429c-b2a9-a262c2765f5e">409</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia48c696724e24052ae23b516c63d79e2_D20210101-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjQtNC0xLTEtMA_da7aef08-6ad2-4f4a-a471-3edea995bb5f">709</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic91169bf44324e9c8beba26b3f9827e7_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjQtNi0xLTEtMA_f8d96815-b389-410b-8fe7-6e28538134df">1,118</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i749f9c098fc64abb9167bd96645abed7_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjQtOC0xLTEtMA_78552b2f-db5c-4b5f-afc4-2a436fe06380">489</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id2cb108abc1b4ddc9555fa47ab4e573b_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjQtMTAtMS0xLTA_d3854214-3564-4b2e-b1ab-32e263494abf">704</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i576d061a6ae043e0829b0988a7faa3ec_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjQtMTItMS0xLTA_295bb39a-255f-4c9a-9692-09583235be6c">1,193</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic52c02bf054740ada11032b24246ae68_D20210101-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjUtMi0xLTEtMA_dc114cea-9539-4ea0-96c2-801610b7a8c9">421</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic6cc0b13a201477e8bdc3a92299b7b68_D20210101-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjUtNC0xLTEtMA_0661c60c-4bd0-4bc9-ba71-00b386bf9df5">423</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id29b4587abfe4026b9589b04316507cb_D20210101-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjUtNi0xLTEtMA_f2fd7175-45ab-48d6-9b6d-8cd9eb69ea36">844</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i99a4a03013b04d41935e841bd095d3a7_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjUtOC0xLTEtMA_b9dc6b17-b5b0-4d97-9263-2a8c2060928d">331</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i6a2c38f1abb049d190286ec739f3d8ae_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjUtMTAtMS0xLTA_94618f28-b884-4041-ae04-0c50c2aa3206">303</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ieb422a6656b54be5afd83d1c3557841c_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjUtMTItMS0xLTA_42fb5881-f460-4d1d-83ca-a418ea6962be">634</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iee523348acf64084b9744fc397411af6_D20210101-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjYtMi0xLTEtMA_b8a91d72-8bde-4441-8322-fe0149780a9d">547</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie2fb5db5ef234ceba2e63133b46811d9_D20210101-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjYtNC0xLTEtMA_32281533-01a3-41c9-8b4c-4da438a68976">277</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia1236d7f1db54d0cbbb4bb10634d9cbd_D20210101-20210930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjYtNi0xLTEtMA_5a42eed2-d4bf-4a68-a8be-9827b397df85">824</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i700316332e8941abafe598d080cee8ed_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjYtOC0xLTEtMA_468c318f-d52d-41f7-8258-72d6fd505d3f">527</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2237615b64f7401e880801b52e994daf_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjYtMTAtMS0xLTA_5a0e7adc-68e3-4883-8057-f4a78eb3f640">266</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3367f489225f42e490b5ec1bd448da76_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjYtMTItMS0xLTA_6922681d-e1c3-435b-b2b4-f7cd69b50351">793</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other products</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie4393fb731674dae95e49ebf43c2dc17_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjctMi0xLTEtMA_492bfd42-aa3c-4d00-ba81-0fadee3c2458">3,059</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2d608ed82a0642d2bd3d2585175ab0df_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjctNC0xLTEtMA_a8d80599-153f-40e7-ba5e-c81b8906dd49">1,974</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7ec4a6f423c548c287970aa87131e9c9_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjctNi0xLTEtMA_dc9bc526-5216-41a1-9c28-263aefb22c49">5,033</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i277af735bdea4ca1ad4911bd0724214d_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjctOC0xLTEtMA_300dfc12-33ac-48f0-a22e-4ca6c8d0dd8c">3,164</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i547f36d7acb3432789479ca670e2143f_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjctMTAtMS0xLTA_db5d19a5-5b45-4d4e-89dd-5abe60f4d180">1,652</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i6ddfacf19b5b4634890a1b86f11498d4_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjctMTItMS0xLTA_b6056282-36d2-4fdf-a33b-0db365915907">4,816</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total product sales</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iec4ac6803eb24d47ae70292430854aee_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjgtMi0xLTEtMA_09e2f6f8-ad00-428a-9b4f-011172c1187d">12,835</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i11c711a9331e402aa04c6f1100a9a662_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjgtNC0xLTEtMA_2900f3d9-12bb-49cd-913d-1ddf2e5f37a6">5,191</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3eb445431b634cc6b3e61727cef7b877_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjgtNi0xLTEtMA_4b41e01e-9e92-4267-b6ec-b1eca7e18ee0">18,026</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="icc040f113aa74ff9aa98ca66ae336cbf_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjgtOC0xLTEtMA_51698992-20db-4094-b016-5a557fcee687">13,325</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i03039f45f78c4280b4623c349760790f_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjgtMTAtMS0xLTA_2ae2eec9-f4c2-4130-9d99-fe59e6213598">4,581</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i556e038dae96477cbe84bc1653ed5883_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjgtMTItMS0xLTA_65c0704c-5dd2-4daf-82cd-67e3a72efa68">17,906</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other revenues</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iddf8eed0ade74615b203cae47895e098_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjktNi0xLTEtMA_c64cd7a6-5ec6-46b1-9574-3ac1388b7074">1,107</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia3ba4d704ab343159b80e5ecde0bf68b_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjktMTItMS0xLTA_82599f48-6b55-4fa9-b5a7-a463434ea4b0">884</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total revenues</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMzAtNi0xLTEtMA_f34c55db-1186-4930-b8de-f183d77f5549">19,133</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMzAtMTItMS0xLTA_44e23343-e94c-405e-8195-c7e1d7599d46">18,790</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:3pt double #000000;padding:0 1pt"></td></tr></table></div><div style="margin-top:4pt;padding-left:13.5pt;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">____________</span></div></ix:nonNumeric></ix:continuation><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"><ix:continuation id="i08c9f75261cb454b8c7f35c7c905b761" continuedAt="i6bf163b64e0d4295901ac903fa9850c9"><ix:continuation id="i96ff44d7f7bb416e8228a481b65d7aac" continuedAt="i312959ccd3e6471ea1325627a2f802ec">(1)&#160;&#160;&#160;&#160;</ix:continuation></ix:continuation></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"><ix:continuation id="i6bf163b64e0d4295901ac903fa9850c9"><ix:continuation id="i312959ccd3e6471ea1325627a2f802ec">Hedging gains and losses, which are included in product sales, were not material for the three and nine months ended September 30, 2021 and 2020.</ix:continuation></ix:continuation> </span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span><br/></span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">9</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_43"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">4. <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:IncomeTaxDisclosureTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfNDc4Nw_e66353e8-9815-4a8f-86ac-215e0de6746f" continuedAt="i9276b47ede5749a1aa5be1edd5b21a9c" escape="true">Income taxes</ix:nonNumeric></span></div><ix:continuation id="i9276b47ede5749a1aa5be1edd5b21a9c"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The effective tax rate for the three and nine months ended September 30, 2021, was <ix:nonFraction unitRef="number" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="3" name="us-gaap:EffectiveIncomeTaxRateContinuingOperations" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfNjk_199677fc-029b-424e-80fc-3aa111545926"><ix:nonFraction unitRef="number" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="3" name="us-gaap:EffectiveIncomeTaxRateContinuingOperations" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfNjk_2f9649e1-39a4-41f7-aa1d-6db6e3f6b37b">12.6</ix:nonFraction></ix:nonFraction>% for both periods, compared with rates of <ix:nonFraction unitRef="number" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="3" name="us-gaap:EffectiveIncomeTaxRateContinuingOperations" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfMTA4_1eae16b8-ad7a-410e-823d-8c503b8399c2"><ix:nonFraction unitRef="number" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="3" name="us-gaap:EffectiveIncomeTaxRateContinuingOperations" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfMTA4_ee081196-76b8-4a29-89bc-d8c0400355a1">8.4</ix:nonFraction></ix:nonFraction>% and <ix:nonFraction unitRef="number" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="3" name="us-gaap:EffectiveIncomeTaxRateContinuingOperations" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfMTE1_db289517-e979-46f8-8cad-09916fcd1e41">9.7</ix:nonFraction>%, respectively, for the corresponding periods of the prior year.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The increase in our effective tax rate for the three and nine months ended September 30, 2021, was primarily due to the non-deductible IPR&amp;D expense arising from the acquisition of Five Prime and prior year favorable items partially offset by a change in earnings mix. The effective tax rates differ from the federal statutory rate primarily as a result of foreign earnings from the Company&#8217;s operations conducted in Puerto Rico, a territory of the United States treated as a foreign jurisdiction for U.S. tax purposes, that are subject to a tax incentive grant through 2035. In addition, the Company&#8217;s operations conducted in Singapore are subject to a tax incentive grant through 2034. These foreign earnings are also subject to U.S. tax at a reduced rate of 10.5%.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The U.S. territory of Puerto Rico imposes an excise tax on the gross intercompany purchase price of goods and services from our manufacturer in Puerto Rico. The rate of 4% is effective through December 31, 2027. We account for the excise tax as a manufacturing cost that is capitalized in inventory and expensed in cost of sales when the related products are sold. For U.S. income tax purposes, the excise tax results in foreign tax credits that are generally recognized in our provision for income taxes when the excise tax is incurred.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">One or more of our legal entities file income tax returns in the U.S. federal jurisdiction, various U.S. state jurisdictions and certain foreign jurisdictions. Our income tax returns are routinely examined by tax authorities in those jurisdictions. Significant disputes may arise with tax authorities involving issues regarding the timing and amount of deductions, the use of tax credits and allocations of income and expenses among various tax jurisdictions because of differing interpretations of tax laws, regulations and relevant facts. In 2017, we received a Revenue Agent Report (RAR) and a modified RAR from the Internal Revenue Service (IRS) for the years 2010, 2011 and 2012 proposing significant adjustments that primarily relate to the allocation of profits between certain of our entities in the United States and the U.S. territory of Puerto Rico. We disagreed with the proposed adjustments and calculations and pursued a resolution with the IRS administrative appeals office. As previously reported, we were unable to reach resolution with the IRS appeals office. In July 2021, we filed a petition in the U.S. Tax Court to contest two duplicate Statutory Notices of Deficiency (Notices) for 2010, 2011 and 2012 that we received in May and July 2021. The duplicate Notices seek to increase our U.S. taxable income by an amount that would result in additional federal tax of approximately $<ix:nonFraction unitRef="usd" contextRef="i91b6753ab42449599e1e80924db35109_I20210531" decimals="-8" format="ixt:num-dot-decimal" name="amgn:ProposedAdditionalIncomeTax" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfMjc3OQ_e2c74c64-38af-420a-a6d8-67fff15b2192">3.6</ix:nonFraction>&#160;billion, plus interest. Any additional tax that could be imposed would be reduced by up to approximately $<ix:nonFraction unitRef="usd" contextRef="i91b6753ab42449599e1e80924db35109_I20210531" decimals="-6" format="ixt:num-dot-decimal" name="amgn:RepatriationTaxOnProposedAdditionalTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfMjg3OQ_37ae7f3b-66f3-423b-8e29-bef1149679df">900</ix:nonFraction>&#160;million of repatriation tax previously accrued on our foreign earnings. In any event, we firmly believe that the IRS&#8217;s positions in the Notices are without merit, and we will vigorously contest the Notices through the judicial process.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:112%">In addition, in 2020, we received an RAR and a modified RAR from the IRS for the years 2013, 2014 and 2015 also proposing significant adjustments that primarily relate to the allocation of profits between certain of our entities in the United States and the U.S. territory of Puerto Rico, similar to those proposed for the years 2010, 2011 and 2012. We disagree with the proposed adjustments and calculations and have been pursuing resolution with the IRS administrative appeals office. As a consequence of the Tax Court litigation for the 2010-2012 period, the IRS administrative appeals office recently informed us that it does not plan to engage in discussions at this time regarding the allocation of profits between our entities in the United States and the U.S. territory of Puerto Rico for the 2013-2015 period. We are currently under examination by the IRS for the years 2016, 2017 and 2018. We are also currently under examination by a number of other state and foreign tax jurisdictions.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:112%">Final resolution of these complex matters is not likely within the next 12 months. We believe our accrual for income tax liabilities is appropriate based on past experience, interpretations of tax law, application of the tax law to our facts and judgments about potential actions by tax authorities; however, due to the complexity of the provision for income taxes and uncertain resolution of these matters, the ultimate outcome of any tax matters may result in payments substantially greater than amounts accrued and could have a material adverse impact on our condensed consolidated financial statements. We are no longer subject to U.S. federal income tax examinations for the years ended on or before December 31, 2009.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">During the three and nine months ended September 30, 2021, the gross amounts of our unrecognized tax benefits (UTBs) increased $<ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfNDU5Mg_20a3a5da-143f-488c-bdd0-557530ae5c5b">70</ix:nonFraction> million and $<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfNDU5OQ_8a4e05cf-d572-4a20-b2cb-342d727abb0c">180</ix:nonFraction>&#160;million, respectively, as a result of tax positions taken during the current year. Substantially all of the UTBs as of September 30, 2021, if recognized, would affect our effective tax rate.</span></div></ix:continuation><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">10</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_46"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">5. <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:EarningsPerShareTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RleHRyZWdpb246YTMyZjgyN2MzYTkwNGI3MzliMzBjOGVhODVkZDc3ZTlfNzQ1_e717e76a-d832-4fef-9358-6b59c0a7b49d" continuedAt="i9cfad9e924d747a1abccacaa00e3b214" escape="true">Earnings per share</ix:nonNumeric></span></div><ix:continuation id="i9cfad9e924d747a1abccacaa00e3b214"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The computation of basic earnings per share (EPS) is based on the weighted-average number of our common shares outstanding. The computation of diluted EPS is based on the weighted-average number of our common shares outstanding and dilutive potential common shares, which primarily include shares that may be issued under our stock option, restricted stock and performance unit award programs (collectively, dilutive securities), as determined by using the treasury stock method.</span></div><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RleHRyZWdpb246YTMyZjgyN2MzYTkwNGI3MzliMzBjOGVhODVkZDc3ZTlfNzYz_050c7f0e-f8a5-40ff-af6a-4eb1010ae3f6" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The computations for basic and diluted EPS were as follows (in millions, except per-share data):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:45.829%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.619%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.619%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.619%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.624%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:120%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income (Numerator):</span></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income for basic and diluted EPS</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMy0xLTEtMS0w_e3da7c8d-ac98-4e86-9fb9-e0024d20494d">1,884</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMy0zLTEtMS0w_1ff34e75-a045-439a-a1f9-6e33b6cc1d0b">2,021</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMy01LTEtMS0w_cdf928ff-1c82-44ca-80ef-02671f90d69a">3,994</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMy03LTEtMS0w_036cba6f-8fd2-4bec-8054-1fd73d635bcc">5,649</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Shares (Denominator):</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Weighted-average shares for basic EPS</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:WeightedAverageNumberOfSharesOutstandingBasic" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNi0xLTEtMS0w_ad16d9f0-7086-44b4-bf05-42784325bfe0">567</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:WeightedAverageNumberOfSharesOutstandingBasic" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNi0zLTEtMS0w_f477fb3f-36cb-4542-9b45-b8bbee5bbc62">585</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:WeightedAverageNumberOfSharesOutstandingBasic" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNi01LTEtMS0w_1a5d64eb-10c8-4adc-b514-2493ff0ce933">572</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:WeightedAverageNumberOfSharesOutstandingBasic" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNi03LTEtMS0w_c3d376fa-eb20-4afb-b3dd-986288434de2">588</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Effect of dilutive securities</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:WeightedAverageNumberDilutedSharesOutstandingAdjustment" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNy0xLTEtMS0w_13ed1f45-c602-45cb-9d72-cdeff44bf6df">3</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:WeightedAverageNumberDilutedSharesOutstandingAdjustment" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNy0zLTEtMS0w_cc019954-9477-45a4-b38a-8d660ad3a55c">4</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:WeightedAverageNumberDilutedSharesOutstandingAdjustment" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNy01LTEtMS0w_c30e0c25-29f2-4136-9dfc-370dd4f247f0">4</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:WeightedAverageNumberDilutedSharesOutstandingAdjustment" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNy03LTEtMS0w_fb572659-14f7-450c-9302-4060413a0c31">4</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Weighted-average shares for diluted EPS</span></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfOC0xLTEtMS0w_319e8e6e-2ae5-4a79-b412-21b6a3a8cb8a">570</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfOC0zLTEtMS0w_1b9dfc19-45e1-4782-b270-f7914f5926be">589</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfOC01LTEtMS0w_5bb39a2a-860d-416d-acdc-82976f5575dc">576</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfOC03LTEtMS0w_55b93733-f88f-4b08-9f89-e4b67cdb367c">592</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Basic EPS</span></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="2" name="us-gaap:EarningsPerShareBasic" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTAtMS0xLTEtMA_598d8279-f390-4e5d-bca6-140305d7fdc4">3.32</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="2" name="us-gaap:EarningsPerShareBasic" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTAtMy0xLTEtMA_149ec296-de56-4b75-9749-8258e55dd424">3.45</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="2" name="us-gaap:EarningsPerShareBasic" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTAtNS0xLTEtMA_1d598ab2-152a-42ca-9729-4c62189dfa26">6.98</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="2" name="us-gaap:EarningsPerShareBasic" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTAtNy0xLTEtMA_01454821-0064-444b-a206-a3a6b6de86f0">9.61</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Diluted EPS</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="2" name="us-gaap:EarningsPerShareDiluted" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTEtMS0xLTEtMA_c2c2c858-601b-4d41-b70a-16c22292d755">3.31</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="2" name="us-gaap:EarningsPerShareDiluted" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTEtMy0xLTEtMA_ed715498-c2e5-4194-9c16-d8fc72e42f0d">3.43</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="2" name="us-gaap:EarningsPerShareDiluted" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTEtNS0xLTEtMA_b89629b3-46a6-4e8a-97cd-8b528d37a977">6.93</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usdPerShare" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="2" name="us-gaap:EarningsPerShareDiluted" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTEtNy0xLTEtMA_17aae5b6-c5d8-48a1-bda3-91804f1637e9">9.54</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div></ix:nonNumeric><div style="text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">For the three and nine months ended September 30, 2021 and 2020, the number of antidilutive employee stock-based awards excluded from the computation of diluted EPS was not significant.</span></div></ix:continuation><div style="margin-bottom:8pt;text-align:justify"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_1088"></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">6. <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:CollaborativeArrangementDisclosureTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xMDg4L2ZyYWc6OGY5MDIzYmQyNTAwNDI0YjhlMWZhNzAzOTE2NjBlM2UvdGV4dHJlZ2lvbjo4ZjkwMjNiZDI1MDA0MjRiOGUxZmE3MDM5MTY2MGUzZV83Njk2NTgxNDA3MTUw_80ab5851-3aee-4df1-b20e-1938494e140f" continuedAt="ie45bc20e893146a599b3b7eea50f8b49" escape="true">Collaborations</ix:nonNumeric></span></div><ix:continuation id="ie45bc20e893146a599b3b7eea50f8b49" continuedAt="iec0f1f77c32c4c5abb5520d56b5b4ac1"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On July 30, 2021, we closed our collaboration and licensing agreement with Kyowa Kirin Co., Ltd. (KKC) to jointly develop and commercialize an anti-OX40 fully human monoclonal antibody (AMG 451) worldwide, except in Japan. AMG 451 is for the treatment of atopic dermatitis, with potential in other autoimmune diseases.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Under the terms of the agreement, we will lead the global development, manufacturing and commercialization of AMG 451, except in Japan. KKC will co-promote AMG 451 with Amgen in the United States and have opt-in rights to co-promote AMG 451 in various other markets outside the United States, including in Europe and Asia. </span></div></ix:continuation><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"><ix:continuation id="iec0f1f77c32c4c5abb5520d56b5b4ac1">We made an upfront payment of $<ix:nonFraction unitRef="usd" contextRef="icb5563aa4d0b4e68b3266d16db71f2a1_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:UpFrontPayment" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xMDg4L2ZyYWc6OGY5MDIzYmQyNTAwNDI0YjhlMWZhNzAzOTE2NjBlM2UvdGV4dHJlZ2lvbjo4ZjkwMjNiZDI1MDA0MjRiOGUxZmE3MDM5MTY2MGUzZV83Njk2NTgxNDA3MjA2_8ac5ea96-8c62-46ed-a72a-16ab2a334425">400</ix:nonFraction>&#160;million to KKC that was recognized in Research and development (R&amp;D) expense in the third quarter of 2021. Amgen and KKC will share equally the global development costs, except in Japan, and the U.S. commercialization costs. Outside of the United States and Japan, any commercialization costs incurred by KKC will be reimbursed by Amgen. We may also be required to make milestone payments of up to $<ix:nonFraction unitRef="usd" contextRef="i1dfc25edd9d84950bcbf296614e005a4_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xMDg4L2ZyYWc6OGY5MDIzYmQyNTAwNDI0YjhlMWZhNzAzOTE2NjBlM2UvdGV4dHJlZ2lvbjo4ZjkwMjNiZDI1MDA0MjRiOGUxZmE3MDM5MTY2MGUzZV83Njk2NTgxNDA3MjIw_44061ebc-03a8-480a-9e22-dfb02723135d">850</ix:nonFraction>&#160;million contingent upon the achievement of certain regulatory events and commercial thresholds. We will also pay KKC significant double-digit royalties on global sales, except in Japan.</ix:continuation> </span></div><div style="text-align:justify;text-indent:22.5pt"><span><br/></span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">11</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_49"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">7. <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNDY5NQ_382040d9-5fb7-47c7-9153-03f722213269" continuedAt="i03687a302ad5491ab31837be52b88596" escape="true">Investments</ix:nonNumeric></span></div><ix:continuation id="i03687a302ad5491ab31837be52b88596" continuedAt="i8186437a30594f118dc545fdd3fc6487"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Available-for-sale investments</span></div><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:DebtSecuritiesAvailableForSaleTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNDc0MA_d807850d-f0b6-4038-bb00-ebf94d23945e" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The amortized cost, gross unrealized gains, gross unrealized losses and fair values of interest-bearing securities, which are considered available-for-sale, by type of security were as follows (in millions):</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:42.174%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.350%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.350%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.350%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.356%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Types of securities as of September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Amortized<br/>cost</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>unrealized<br/>gains</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>unrealized<br/>losses</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair<br/>values</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i0523566bb4bd4ac7a167861d41b07412_I20210930" decimals="-6" name="us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMS0yLTEtMS0w_7b0fc87c-cfff-464b-afd9-7bdc622f8de9">51</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i0523566bb4bd4ac7a167861d41b07412_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMS00LTEtMS0w_3b258ead-7562-4417-8b7a-62071e24e378">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i0523566bb4bd4ac7a167861d41b07412_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMS02LTEtMS0w_177ed699-3cc2-4b97-9151-a7a7b2a871f4">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i0523566bb4bd4ac7a167861d41b07412_I20210930" decimals="-6" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMS04LTEtMS0w_17c0bbc2-e3ba-43fc-8ff5-db8cd27ec069">51</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury bills</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8db023e72bf0457098764c83dfe06255_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMi0yLTEtMS0w_cb30ac17-49ef-41c8-bc77-d9a877ab8664">3,900</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8db023e72bf0457098764c83dfe06255_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMi00LTEtMS0w_fd467c46-c02d-48ae-87e1-b1fb3bd7b63b">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8db023e72bf0457098764c83dfe06255_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMi02LTEtMS0w_f8c34fb0-81c7-4045-9d69-df5d6a5949d7">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8db023e72bf0457098764c83dfe06255_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMi04LTEtMS0w_5e740994-1b85-439b-8f1c-ea290c7dfd02">3,900</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Money market mutual funds</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3022e170e868460588b8873ad8b918de_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTItMi0xLTEtMA_c2e011ab-f19f-4bc4-a6d7-4918e68681ec">8,323</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3022e170e868460588b8873ad8b918de_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTItNC0xLTEtMA_f6b7a9b8-9067-4650-a445-165de43c2156">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3022e170e868460588b8873ad8b918de_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTItNi0xLTEtMA_6ad8effe-96ec-4b27-add2-c8b30964d721">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3022e170e868460588b8873ad8b918de_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTItOC0xLTEtMA_6f86a523-42eb-4e81-a66f-d4d978051383">8,323</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other short-term interest-bearing securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic7d3b5bd8e574e95949520f4cff15af1_I20210930" decimals="-6" name="us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTMtMi0xLTEtMA_baf0a0dc-2b07-4046-ada5-c5d2614072a7">1</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic7d3b5bd8e574e95949520f4cff15af1_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTMtNC0xLTEtMA_e6d7686d-4b47-464b-916e-dcdf30675cf5">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic7d3b5bd8e574e95949520f4cff15af1_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTMtNi0xLTEtMA_e84df3c2-f5b8-480c-8723-a5e9d54a3f2b">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic7d3b5bd8e574e95949520f4cff15af1_I20210930" decimals="-6" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTMtOC0xLTEtMA_a2887273-b074-48a4-a0de-d7f88ac583ab">1</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total interest-bearing securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTYtMi0xLTEtMA_c2ac0ba4-d62b-40d7-a486-9d95188417ee">12,275</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTYtNC0xLTEtMA_5cba5501-c49f-4214-b611-c88e190f4e0c">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTYtNi0xLTEtMA_691bfb98-5a11-46e5-99a5-e6dc6f16079f">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTYtOC0xLTEtMA_803a0be5-b278-4d56-bca1-fc3793897cb2">12,275</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div><span><br/></span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:42.174%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.350%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.350%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.350%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.356%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Types of securities as of December 31, 2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Amortized<br/>cost</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>unrealized<br/>gains</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>unrealized<br/>losses</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair<br/>values</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i507488fbf87d4c6296eb13e3e0006fbf_I20201231" decimals="-6" name="us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMS0yLTEtMS0w_b073ae35-8215-4e16-868f-dc0ab8e62044">129</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i507488fbf87d4c6296eb13e3e0006fbf_I20201231" decimals="-6" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMS00LTEtMS0w_2f3a8107-4b10-42bc-93f7-588ef43562c3">1</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i507488fbf87d4c6296eb13e3e0006fbf_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMS02LTEtMS0w_ec1b261e-c11a-43a0-a498-c046ad0fda54">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i507488fbf87d4c6296eb13e3e0006fbf_I20201231" decimals="-6" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMS04LTEtMS0w_821c9976-2b6a-489d-a07c-4b9cfee84192">130</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury bills</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8ba30f0c09fc4bfd9fe36a47079d2854_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMi0yLTEtMS0w_97c901c1-2670-465a-9637-c30c6456e7e7">4,948</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8ba30f0c09fc4bfd9fe36a47079d2854_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMi00LTEtMS0w_47a979ee-0eeb-4bf8-bfbe-cc0bbd08057a">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8ba30f0c09fc4bfd9fe36a47079d2854_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMi02LTEtMS0w_05a49f0d-ebab-402b-92e9-d78d9de0bf02">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8ba30f0c09fc4bfd9fe36a47079d2854_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMi04LTEtMS0w_3ab40ab0-f380-433e-adba-cd1731f50414">4,948</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Money market mutual funds</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i54f838959ac943e79d09dcf9e6faada4_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTItMi0xLTEtMA_a1ea0363-8b4b-4fe8-9b00-734896df6c49">4,765</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i54f838959ac943e79d09dcf9e6faada4_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTItNC0xLTEtMA_ea07f742-3a42-43e8-8076-46991b766b67">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i54f838959ac943e79d09dcf9e6faada4_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTItNi0xLTEtMA_88ceae73-b76c-49d4-8658-bab9efa3fd43">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i54f838959ac943e79d09dcf9e6faada4_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTItOC0xLTEtMA_52e58e2a-858d-44f7-9d72-fcf6545f4169">4,765</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other short-term interest-bearing securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i84edbdc908bc4493a769cf963ac32f28_I20201231" decimals="-6" name="us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTMtMi0xLTEtMA_feb3b98c-84f0-4040-82fa-f2bda0660dda">2</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i84edbdc908bc4493a769cf963ac32f28_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTMtNC0xLTEtMA_dce2acfe-619f-4371-a5dc-f2b7adee31ed">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i84edbdc908bc4493a769cf963ac32f28_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTMtNi0xLTEtMA_3b701d2a-b586-4162-acd6-7eda21a99452">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i84edbdc908bc4493a769cf963ac32f28_I20201231" decimals="-6" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTMtOC0xLTEtMA_b458b5f4-6da7-4186-94c9-4982908fb40f">2</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total interest-bearing securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTQtMi0xLTEtMA_de87e067-e85e-42de-9309-ebac2da99dff">9,844</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTQtNC0xLTEtMA_9d39308f-b619-495c-9c8a-269369c78c17">1</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTQtNi0xLTEtMA_0e29cb00-59d6-44c6-a8e2-e2705894efd4">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTQtOC0xLTEtMA_52474026-260e-4659-987c-6febf6db20c2">9,845</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div></ix:nonNumeric><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="amgn:FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNDc1Nw_1a4c348a-d27a-401e-b876-83d4882296de" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of interest-bearing securities by location in the Condensed Consolidated Balance Sheets were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:64.397%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.420%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.423%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated Balance Sheets locations</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash and cash equivalents</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i6a8d71c465184aa38c33193a90315560_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CashAndCashEquivalentsFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmY5M2FhZWEyNzZmNDRiMGJhMTUzZTE2NTYzYTM5OGEzL3RhYmxlcmFuZ2U6ZjkzYWFlYTI3NmY0NGIwYmExNTNlMTY1NjNhMzk4YTNfMS0yLTEtMS0w_b77aa85a-efac-467b-871a-4b4696e3529b">11,323</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d779b254da4c18b8454e5bf7051777_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:CashAndCashEquivalentsFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmY5M2FhZWEyNzZmNDRiMGJhMTUzZTE2NTYzYTM5OGEzL3RhYmxlcmFuZ2U6ZjkzYWFlYTI3NmY0NGIwYmExNTNlMTY1NjNhMzk4YTNfMS00LTEtMS0w_75ac1cf6-465d-4dde-8d4e-ac1a37b05270">5,464</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Marketable securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i6a8d71c465184aa38c33193a90315560_I20210930" decimals="-6" name="us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmY5M2FhZWEyNzZmNDRiMGJhMTUzZTE2NTYzYTM5OGEzL3RhYmxlcmFuZ2U6ZjkzYWFlYTI3NmY0NGIwYmExNTNlMTY1NjNhMzk4YTNfMi0yLTEtMS0w_249418f4-987a-4ec9-95bb-5885ea7c2ae1">952</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d779b254da4c18b8454e5bf7051777_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmY5M2FhZWEyNzZmNDRiMGJhMTUzZTE2NTYzYTM5OGEzL3RhYmxlcmFuZ2U6ZjkzYWFlYTI3NmY0NGIwYmExNTNlMTY1NjNhMzk4YTNfMi00LTEtMS0w_733acc17-5986-4520-aad0-ee495ff83b67">4,381</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total interest-bearing securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i6a8d71c465184aa38c33193a90315560_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmY5M2FhZWEyNzZmNDRiMGJhMTUzZTE2NTYzYTM5OGEzL3RhYmxlcmFuZ2U6ZjkzYWFlYTI3NmY0NGIwYmExNTNlMTY1NjNhMzk4YTNfMy0yLTEtMS0w_5f453225-9ed7-48c4-843a-67954baa2c04">12,275</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d779b254da4c18b8454e5bf7051777_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmY5M2FhZWEyNzZmNDRiMGJhMTUzZTE2NTYzYTM5OGEzL3RhYmxlcmFuZ2U6ZjkzYWFlYTI3NmY0NGIwYmExNTNlMTY1NjNhMzk4YTNfMy00LTEtMS0w_7c9fbe7f-377b-4e89-9f83-95cbcdc32da5">9,845</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div></ix:nonNumeric><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Cash and cash equivalents in the above table excludes bank account cash of $<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:Cash" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNDcw_f874d811-43b7-432d-bbbf-3903e25680f5">646</ix:nonFraction> million and $<ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:Cash" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNDc3_8dc7b353-8703-4a5d-9c54-8ebaf2585b86">802</ix:nonFraction>&#160;million as of September 30, 2021 and December 31, 2020, respectively.</span></div><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:InvestmentsClassifiedByContractualMaturityDateTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNDcwMw_577848ef-d0a8-4182-ab39-26be4fdd1488" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of available-for-sale investments by contractual maturity were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:64.397%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.420%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.423%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Contractual maturities</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Maturing in one year or less</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmJkN2ExNjFmZGE4OTQ4ZGJiN2FhNjhhYThlMjgwODJlL3RhYmxlcmFuZ2U6YmQ3YTE2MWZkYTg5NDhkYmI3YWE2OGFhOGUyODA4MmVfMS0yLTEtMS0w_e3c79901-7b00-4d89-8ace-b053bcefc92f">12,275</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmJkN2ExNjFmZGE4OTQ4ZGJiN2FhNjhhYThlMjgwODJlL3RhYmxlcmFuZ2U6YmQ3YTE2MWZkYTg5NDhkYmI3YWE2OGFhOGUyODA4MmVfMS00LTEtMS0w_2fe9b5ac-bb85-43b5-b568-2a71cf1339a5">9,795</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Maturing after one year through three years</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:fixed-zero" name="amgn:AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmJkN2ExNjFmZGE4OTQ4ZGJiN2FhNjhhYThlMjgwODJlL3RhYmxlcmFuZ2U6YmQ3YTE2MWZkYTg5NDhkYmI3YWE2OGFhOGUyODA4MmVfMi0yLTEtMS0w_20f860f8-5d70-44fb-8818-0ddab4737473">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" name="amgn:AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmJkN2ExNjFmZGE4OTQ4ZGJiN2FhNjhhYThlMjgwODJlL3RhYmxlcmFuZ2U6YmQ3YTE2MWZkYTg5NDhkYmI3YWE2OGFhOGUyODA4MmVfMi00LTEtMS0w_713bb288-3486-4adc-81db-eeb22b882f47">50</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total available-for-sale investments </span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmJkN2ExNjFmZGE4OTQ4ZGJiN2FhNjhhYThlMjgwODJlL3RhYmxlcmFuZ2U6YmQ3YTE2MWZkYTg5NDhkYmI3YWE2OGFhOGUyODA4MmVfNy0yLTEtMS0w_62539ff8-409c-4fe0-a1b3-5fc8f5b202d4">12,275</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmJkN2ExNjFmZGE4OTQ4ZGJiN2FhNjhhYThlMjgwODJlL3RhYmxlcmFuZ2U6YmQ3YTE2MWZkYTg5NDhkYmI3YWE2OGFhOGUyODA4MmVfNy00LTEtMS0w_bb29db13-fc82-4178-b02b-94fa6437403c">9,845</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div></ix:nonNumeric><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">For the three and nine months ended September 30, 2021 and 2020, realized gains and losses on interest-bearing securities were not material. Realized gains and losses on interest-bearing securities are recorded in Other income, net, in the Condensed Consolidated Statements of Income. The cost of securities sold is based on the specific-identification method.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The primary objective of our investment portfolio is to maintain safety of principal, prudent levels of liquidity and acceptable levels of risk. Our investment policy limits interest-bearing security investments to certain types of debt and money market instruments issued by institutions with investment-grade credit ratings, and it places restrictions on maturities and concentration by asset class and issuer. </span></div></ix:continuation><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">12</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><ix:continuation id="i8186437a30594f118dc545fdd3fc6487"><div style="margin-bottom:8pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Equity securities</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We held investments in equity securities with readily determinable fair values (publicly traded securities) of $<ix:nonFraction unitRef="usd" contextRef="ib2b89ed4eb094c5f966961837399b7ca_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:EquitySecuritiesFvNi" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMTQ4OA_0d7d248b-77f5-4e77-8f6f-a39beaf986c5">608</ix:nonFraction> million and $<ix:nonFraction unitRef="usd" contextRef="ia0271b62203b4afbbefbea6461a32a14_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:EquitySecuritiesFvNi" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMTQ5NQ_103cb2b0-529d-475d-acc6-f7e896d6990b">477</ix:nonFraction> million as of September 30, 2021 and December 31, 2020, respectively, which are included in Other noncurrent assets in the Condensed Consolidated Balance Sheets. For the three months ended September 30, 2021 and 2020, net unrealized gains on publicly traded securities were $<ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMTcwNA_ce850d56-9a36-4635-a150-418df433efa1">135</ix:nonFraction>&#160;million and $<ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMTcxMQ_24842655-9503-4254-85ed-d1d92e53e271">60</ix:nonFraction>&#160;million, respectively. For the nine months ended September 30, 2021 and 2020, net unrealized gains on publicly traded securities were $<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMTgzNA_0a6187bd-98f4-4c10-93ca-740a6e79a68d">104</ix:nonFraction>&#160;million and $<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMTg1Mg_8936974f-4a49-4989-8570-ebdd5f8a09c9">65</ix:nonFraction>&#160;million, respectively. Realized gains and losses on sales of publicly traded securities for the three and nine months ended September 30, 2021 and 2020 were not material.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We held investments of $<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMjAxMg_02b46afa-f8de-40f1-8c4a-9743720264ac">255</ix:nonFraction> million and $<ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMjAxOQ_26c99ce5-bb58-4006-b0f6-c7590986d338">203</ix:nonFraction> million in equity securities without readily determinable fair values as of September 30, 2021 and December 31, 2020, respectively, which are included in Other noncurrent assets in the Condensed Consolidated Balance Sheets. For the three months ended September 30, 2021 and 2020, gains due to upward adjustments on these securities were $<ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQwNDM4OQ_d428d37c-acfb-4cfe-9e83-204549ad6ea4">94</ix:nonFraction>&#160;million and $<ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQwNDQxOQ_90e4e7d4-1a2e-4957-843f-f0f7027cf577">12</ix:nonFraction>&#160;million, respectively. For the nine months ended September 30, 2021 and 2020, gains due to upward adjustments on these securities were $<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfODI0NjMzNzIyODE2OQ_686dea5f-4852-4496-a506-09d9bbe28859">129</ix:nonFraction>&#160;million and $<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQwNDQwNg_de169609-7d2e-4882-a1c4-ea996f5d0703">20</ix:nonFraction>&#160;million, respectively. Downward adjustments on these securities were not material. Adjustments were based on observable price transactions.</span></div><div style="margin-bottom:8pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Equity method investments </span></div><div style="margin-bottom:8pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">BeiGene, Ltd.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">As of September 30, 2021, we had an ownership interest of approximately <ix:nonFraction unitRef="number" contextRef="i88ba0aea99ef48b08518a135f9c253ef_I20210930" decimals="3" name="us-gaap:EquityMethodInvestmentOwnershipPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfOTg5NTYwNDY2MTA1Mw_344b8f0d-c165-4b9f-bb2f-efbf95ed4046">20.3</ix:nonFraction>% in BeiGene, Ltd. (BeiGene), which is included in Other noncurrent assets in the Condensed Consolidated Balance Sheets and accounted for under the equity method of accounting. We amortize the difference between the fair value of equity securities acquired and our proportionate share of the carrying value of the underlying net assets of BeiGene over the useful lives of the assets that gave rise to this basis difference. This amortization and our share of the results of operations of BeiGene are included in </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Other income, net</span><span style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, in the Condensed Consolidated Statements of Income one quarter in arrears, which began in the second quarter of 2020. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">During the three and nine months ended September 30, 2021, the carrying value of our equity investment was adjusted by our share of BeiGene&#8217;s net loss of $<ix:nonFraction unitRef="usd" contextRef="ib7d74024b547459c9c043788d26b2171_D20210701-20210930" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:IncomeLossFromEquityMethodInvestments" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDExOA_e3ef4bb8-8367-4e2e-b7cf-955d293b6eb1">98</ix:nonFraction>&#160;million and $<ix:nonFraction unitRef="usd" contextRef="i425bed6d2b57481aba5c27ce44f41234_D20210101-20210930" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="us-gaap:IncomeLossFromEquityMethodInvestments" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDEzOA_468ff9c0-ae9e-4ef8-9ead-cf046b8ba39b">181</ix:nonFraction>&#160;million, respectively, and amortization of the basis difference of $<ix:nonFraction unitRef="usd" contextRef="ib7d74024b547459c9c043788d26b2171_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDExMA_a51e5bff-aa74-437a-a846-ac35d1922700">44</ix:nonFraction>&#160;million and $<ix:nonFraction unitRef="usd" contextRef="i425bed6d2b57481aba5c27ce44f41234_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDExNA_a851498e-4b19-44fb-b599-124e9b040991">128</ix:nonFraction>&#160;million, respectively. During the three and nine months ended September 30, 2021, the carrying value increased by $<ix:nonFraction unitRef="usd" contextRef="ib7d74024b547459c9c043788d26b2171_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:EquityMethodInvestmentChangeInCarryingValueOther" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDEwNg_e63ffbd2-26c0-4b6e-b47a-7fa0bfcbff62">18</ix:nonFraction>&#160;million and $<ix:nonFraction unitRef="usd" contextRef="i425bed6d2b57481aba5c27ce44f41234_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:EquityMethodInvestmentChangeInCarryingValueOther" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDEwMg_f95213d0-5ac7-4a00-9ab1-844926e90daf">56</ix:nonFraction>&#160;million, respectively, from the impact of BeiGene ownership transactions. In addition, during the three and nine months ended September 30, 2021, we increased the carrying value by $<ix:nonFraction unitRef="usd" contextRef="ib7d74024b547459c9c043788d26b2171_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:EquityMethodInvestmentChangeInCarryingValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDI1Nw_609872ab-128a-4a45-b67e-7b15bb80ed74"><ix:nonFraction unitRef="usd" contextRef="i425bed6d2b57481aba5c27ce44f41234_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:EquityMethodInvestmentChangeInCarryingValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDI1Nw_de51f072-77e9-4fc0-907a-8b267511d28e">50</ix:nonFraction></ix:nonFraction>&#160;million as a result of our purchase of additional shares directly from BeiGene. As of September 30, 2021, the carrying value and fair value of our investment in BeiGene totaled $<ix:nonFraction unitRef="usd" contextRef="i88ba0aea99ef48b08518a135f9c253ef_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:EquityMethodInvestments" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfOTg5NTYwNDY2MjMxNQ_d40d12db-b66c-46d7-b84c-b273509818a1">2.7</ix:nonFraction> billion and $<ix:nonFraction unitRef="usd" contextRef="i88ba0aea99ef48b08518a135f9c253ef_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:EquityMethodInvestmentQuotedMarketValue" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfOTg5NTYwNDY2MjMyNA_4525a57c-7aa8-429a-bb64-5080d087d94d">6.9</ix:nonFraction> billion, respectively. As of September 30, 2021, we believe the carrying value of our equity investment in BeiGene is fully recoverable.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Neumora Therapeutics, Inc.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> On September 30, 2021, we acquired approximately <ix:nonFraction unitRef="number" contextRef="i14a1d9538f0a492885a9966112c392aa_I20210930" decimals="3" name="us-gaap:EquityMethodInvestmentOwnershipPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDE4MQ_c9da4339-ca7f-4ce8-a998-c775ea17e5da">25.9</ix:nonFraction>% ownership interest in Neumora Therapeutics, Inc. (Neumora), a privately held company, for $<ix:nonFraction unitRef="usd" contextRef="i14a1d9538f0a492885a9966112c392aa_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:EquityMethodInvestmentAggregateCost" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDE2Ng_55ed510c-915d-4d16-a7a5-b3ddd24ebb25">257</ix:nonFraction>&#160;million, which is included in Other noncurrent assets in the Condensed Consolidated Balance Sheets, in exchange for a $<ix:nonFraction unitRef="usd" contextRef="i3c3ace434f6b40b4a14815a09b06178b_D20210930-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:PaymentsToAcquireEquityMethodInvestments" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDE4NQ_cf26715a-c00d-406c-a599-2f264fee1a4e">100</ix:nonFraction>&#160;million cash payment and $<ix:nonFraction unitRef="usd" contextRef="i3c3ace434f6b40b4a14815a09b06178b_D20210930-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:NoncashOrPartNoncashAcquisitionInvestmentsAcquired1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDE4OQ_32eaf2b0-92ad-4ec6-b393-a29b891a4bd0">157</ix:nonFraction>&#160;million in noncash consideration primarily related to future services. Although our equity investment provides us with the ability to exercise significant influence over Neumora, we have elected the fair value option to account for our equity investment. Under the fair value option, changes in the fair value of the investment are recognized through earnings each reporting period. We believe the fair value option best reflects the economics of the underlying transaction. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Limited partnerships</span></div><div style="text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We held limited partnership investments of $<ix:nonFraction unitRef="usd" contextRef="ic38268b0440c4532956b86d64e30b988_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AlternativeInvestment" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMjQ1OQ_9f024e6f-c6de-43f7-b194-4b7c3f818b22">556</ix:nonFraction> million and $<ix:nonFraction unitRef="usd" contextRef="i84a786cd4d99438e85fec21c4c798f36_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AlternativeInvestment" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMjQ2Ng_0ece5f1e-1455-4559-b5cc-1c16ae8b9f71">496</ix:nonFraction> million as of September 30, 2021 and December 31, 2020, respectively, which are included in Other noncurrent assets in the Condensed Consolidated Balance Sheets. These investments, primarily investment funds of early-stage biotechnology companies, are accounted for by using the equity method of accounting and are measured by using our proportionate share of the net asset values of the underlying investments held by the limited partnerships as a practical expedient. These investments are typically redeemable only through distributions upon liquidation of the underlying assets. As of September 30, 2021, unfunded additional commitments to be made for these investments during the next several years were not material. For the three months ended September 30, 2021 and 2020, net unrealized gains and losses on our limited partnership investments were a net loss of $<ix:nonFraction unitRef="usd" contextRef="i01c954a7c8fa422990f7456e349536ec_D20210701-20210930" decimals="-6" sign="-" format="ixt:num-dot-decimal" name="amgn:AlternativeInvestmentNetGainLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMzIzMg_98de8dec-27a1-4fef-b29f-27f5c251ed2d">43</ix:nonFraction>&#160;million and a net gain of $<ix:nonFraction unitRef="usd" contextRef="i9a95e7ba909f487d97ae171134923478_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:AlternativeInvestmentNetGainLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMzIzOQ_0202569f-f6fe-405d-9b3b-3aab10a9e405">63</ix:nonFraction>&#160;million, respectively. For the nine months ended September 30, 2021 and 2020, net unrealized gains from our limited partnership investments were $<ix:nonFraction unitRef="usd" contextRef="i2fcb95887a864539b58641131094dfd5_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:AlternativeInvestmentNetGainLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMzM2MA_b9b3e03e-eea4-427b-98bc-d6c0d7db75b6">122</ix:nonFraction>&#160;million and $<ix:nonFraction unitRef="usd" contextRef="i7d119868ff92459e8484a254322dda06_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:AlternativeInvestmentNetGainLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMzM2Nw_508b7074-848f-492c-bc4e-66da38541110">73</ix:nonFraction>&#160;million, respectively.</span></div></ix:continuation><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">13</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_52"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">8. <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:InventoryDisclosureTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RleHRyZWdpb246MTE2MDZkZTNlYzRmNDgxMDkxZGYxODdlNmE0ODNjZTZfNzM_fea078b8-e46f-41a5-946e-303ddf58671b" continuedAt="i8efaa4b615ac4bbc81e0cb0402f222e4" escape="true">Inventories</ix:nonNumeric></span></div><ix:continuation id="i8efaa4b615ac4bbc81e0cb0402f222e4"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:ScheduleOfInventoryCurrentTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RleHRyZWdpb246MTE2MDZkZTNlYzRmNDgxMDkxZGYxODdlNmE0ODNjZTZfNzg_39c79543-bb18-45b3-a21c-4394de6bd61d" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Inventories consisted of the following (in millions):</span></div><div><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:65.128%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.420%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.422%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Raw materials</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" name="us-gaap:InventoryRawMaterialsNetOfReserves" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfMS0xLTEtMS0w_546bcf9c-de4d-4441-bce8-bc0922d5a7b2">667</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" name="us-gaap:InventoryRawMaterialsNetOfReserves" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfMS0zLTEtMS0w_871c82e9-8ce4-480e-be4b-8b9016d716e0">486</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Work in process</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:InventoryWorkInProcessNetOfReserves" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfMi0xLTEtMS0w_1b9b4f84-44a4-4fb3-b9e8-f943e2384229">2,313</ix:nonFraction>&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:InventoryWorkInProcessNetOfReserves" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfMi0zLTEtMS0w_c9279222-0622-4957-89c2-b740dfc34ecb">2,437</ix:nonFraction>&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Finished goods</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:InventoryFinishedGoodsNetOfReserves" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfMy0xLTEtMS0w_344c14c4-95aa-4f24-b454-f49872f4be85">1,172</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" name="us-gaap:InventoryFinishedGoodsNetOfReserves" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfMy0zLTEtMS0w_224e2f0f-fd1b-4ba9-b1ee-a2d130672fd8">970</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 5.5pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total inventories</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:InventoryNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfNC0xLTEtMS0w_9dcdcbe7-6cce-4c13-b4b6-f0108cf6d308">4,152</ix:nonFraction>&#160;</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:InventoryNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfNC0zLTEtMS0w_693fe415-5e8b-4cf5-b344-df2b9e5845c4">3,893</ix:nonFraction>&#160;</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div></ix:nonNumeric></ix:continuation><div id="i0b2dd96150e340208a57faec23ec2da5_55"></div><div style="margin-top:9pt;text-align:justify"><span><br/></span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">9. <ix:nonNumeric contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" name="us-gaap:GoodwillAndIntangibleAssetsDisclosureTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTkxMg_808b001b-8247-446a-8e8e-437babf35dde" continuedAt="ice3c1a691651458fa53db077213e0b40" escape="true">Goodwill and other intangible assets</ix:nonNumeric></span></div><ix:continuation id="ice3c1a691651458fa53db077213e0b40" continuedAt="i58b1ead60eba40a796f224c74dc0af05"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Goodwill</span></div><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:ScheduleOfGoodwillTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTkyMw_d1b92ad7-8296-4f5a-ac87-02e7d405444f" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The change in the carrying amount of goodwill was as follows (in millions):</span></div><div><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.707%"><tr><td style="width:1.0%"></td><td style="width:82.331%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.469%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30, 2021</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Beginning balance</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:Goodwill" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOjg4MTE1ZjlhZGI1YjRhOTc5M2Q5M2MzNDcyMzI0OGNiL3RhYmxlcmFuZ2U6ODgxMTVmOWFkYjViNGE5NzkzZDkzYzM0NzIzMjQ4Y2JfMS0xLTEtMS0w_98dc9c75-5136-4638-a98e-f5d18d4c3156">14,689</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Currency translation adjustment</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:GoodwillForeignCurrencyTranslationGainLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOjg4MTE1ZjlhZGI1YjRhOTc5M2Q5M2MzNDcyMzI0OGNiL3RhYmxlcmFuZ2U6ODgxMTVmOWFkYjViNGE5NzkzZDkzYzM0NzIzMjQ4Y2JfMi0xLTEtMS0w_57dcb140-f536-42a2-93f8-f6e2a6606e02">24</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Ending balance</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:Goodwill" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOjg4MTE1ZjlhZGI1YjRhOTc5M2Q5M2MzNDcyMzI0OGNiL3RhYmxlcmFuZ2U6ODgxMTVmOWFkYjViNGE5NzkzZDkzYzM0NzIzMjQ4Y2JfMy0xLTEtMS0w_1f201e21-631e-49d4-937b-e3fc786fa46f">14,665</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div></ix:nonNumeric><div style="text-align:justify"><span><br/></span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Other intangible assets</span></div><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="amgn:ScheduleOfIntangibleAssetsTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTkxMA_47606a9c-5dfe-44db-b916-61f447167900" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Other intangible assets consisted of the following (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:32.087%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.433%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>carrying<br/>amounts</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Accumulated<br/>amortization</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other intangible<br/>assets, net</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>carrying<br/>amounts</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Accumulated<br/>amortization</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other intangible<br/>assets, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Finite-lived intangible assets:</span></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Developed-product-technology rights</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9160bae8d5f74cf4a23fbe7ba32fa1b6_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsGross" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMy0xLTEtMS0w_5ea507ab-dd61-4245-9be8-a6ea0bd1e125">25,575</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i9160bae8d5f74cf4a23fbe7ba32fa1b6_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMy0zLTEtMS0w_f07ca834-6219-4141-89a3-f112fe7d1812">12,222</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9160bae8d5f74cf4a23fbe7ba32fa1b6_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMy01LTEtMS0w_f2d569c5-75f5-4721-a246-ead4e8f3ca3d">13,353</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ibb2cb97dcaa2448f8abb52ea2809f752_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsGross" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMy03LTEtMS0w_4a35e7d1-fed5-47c2-8e5e-e0095cd43f47">25,591</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ibb2cb97dcaa2448f8abb52ea2809f752_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMy05LTEtMS0w_c56a132b-56b1-4eac-998d-267fb0b8f168">10,564</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ibb2cb97dcaa2448f8abb52ea2809f752_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMy0xMS0xLTEtMA_25335458-49d0-4cbb-9ac8-96be0dba5a96">15,027</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Licensing rights</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iccda3c90f3ea4d7ca11b1e7e5979139f_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsGross" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNC0xLTEtMS0w_fc26d80f-8561-4490-97df-e990b5908c95">3,766</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="iccda3c90f3ea4d7ca11b1e7e5979139f_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNC0zLTEtMS0w_86d5fd00-f9ab-472a-aba8-c7ead75472a0">2,931</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iccda3c90f3ea4d7ca11b1e7e5979139f_I20210930" decimals="-6" name="us-gaap:FiniteLivedIntangibleAssetsNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNC01LTEtMS0w_62d402cb-549e-4849-b065-88f11dadc035">835</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7bfe3a17c67f48848b0a262301253745_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsGross" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNC03LTEtMS0w_e041a71a-869c-44e8-a639-e92dfac4bc69">3,743</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i7bfe3a17c67f48848b0a262301253745_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNC05LTEtMS0w_ad8b16b9-9787-4ec3-9356-70d520576352">2,791</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7bfe3a17c67f48848b0a262301253745_I20201231" decimals="-6" name="us-gaap:FiniteLivedIntangibleAssetsNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNC0xMS0xLTEtMA_6858b425-1181-4ebd-a779-c87541ee385c">952</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Marketing-related rights</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie5cd36de21a24c3a974d783bc31683e3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsGross" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNS0xLTEtMS0w_76f6d887-c7d3-4830-9c87-953e4ec82510">1,362</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ie5cd36de21a24c3a974d783bc31683e3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNS0zLTEtMS0w_bd74c6c5-1015-484a-afd9-0d0a89bdddc2">1,099</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie5cd36de21a24c3a974d783bc31683e3_I20210930" decimals="-6" name="us-gaap:FiniteLivedIntangibleAssetsNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNS01LTEtMS0w_0f1f78ce-c837-441f-bebe-ce42b4af4dec">263</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ifa42c9c20230405db95ebc7c2717a086_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsGross" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNS03LTEtMS0w_dbf0ca28-6112-4a77-af56-04015d403208">1,367</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ifa42c9c20230405db95ebc7c2717a086_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNS05LTEtMS0w_14c33ecf-3256-4ed4-81dc-6f021c8e0014">1,041</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ifa42c9c20230405db95ebc7c2717a086_I20201231" decimals="-6" name="us-gaap:FiniteLivedIntangibleAssetsNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNS0xMS0xLTEtMA_f638f4d9-8aa9-4aa5-aff2-bd8d978cd7c7">326</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Research and development technology rights</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i823fc181443240599bbbbaad667a7fd2_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsGross" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNi0xLTEtMS0w_eebde804-68d6-4a44-9aa3-30a8a062c174">1,298</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i823fc181443240599bbbbaad667a7fd2_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNi0zLTEtMS0w_046fbaa5-0d51-4001-adfc-a356aa964b19">1,120</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i823fc181443240599bbbbaad667a7fd2_I20210930" decimals="-6" name="us-gaap:FiniteLivedIntangibleAssetsNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNi01LTEtMS0w_dda279aa-f29c-4150-882d-4171d685a661">178</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3c93fbbb176e41ab97226ab5c020020d_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsGross" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNi03LTEtMS0w_926d028b-916f-47d0-9bee-8a8ef8778724">1,317</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i3c93fbbb176e41ab97226ab5c020020d_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNi05LTEtMS0w_c42fadc3-407c-4dcc-9950-8cb4363eb72d">1,065</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3c93fbbb176e41ab97226ab5c020020d_I20201231" decimals="-6" name="us-gaap:FiniteLivedIntangibleAssetsNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNi0xMS0xLTEtMA_eafb08ad-ed19-4e97-b1f6-9be52ee985ed">252</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total finite-lived intangible assets</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsGross" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNy0xLTEtMS0w_62f2de0e-536a-4bb9-b2a6-4969afb81554">32,001</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNy0zLTEtMS0w_161717a6-9bf8-431f-85ac-41ccfcb2ece2">17,372</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNy01LTEtMS0w_9dba70a2-3a06-425a-b893-3913695d18a5">14,629</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsGross" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNy03LTEtMS0w_8989105d-7e9d-4d5e-8aa4-cc78847746fe">32,018</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNy05LTEtMS0w_c7225c5a-0950-468f-8335-3d34718e5401">15,461</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNy0xMS0xLTEtMA_d49bcf7d-a83a-4fc8-a8a0-5aecb1f953a6">16,557</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Indefinite-lived intangible assets:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">In-process research and development</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i62a4ce9947344dd28aeec0db74164aef_I20210930" decimals="-6" name="us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfOS0xLTEtMS0w_cc839bf2-6537-4985-8f52-18532c1f9eed">30</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i62a4ce9947344dd28aeec0db74164aef_I20210930" decimals="-6" name="us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfOS01LTEtMS0w_35e3a7ba-5ece-4e49-a081-06f47137a8cb">30</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i858e9c4fb9dc48f1b8c2568fc92c7dfd_I20201231" decimals="-6" name="us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfOS03LTEtMS0w_b95d4f71-6937-480b-bc0f-bb79720315ec">30</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i858e9c4fb9dc48f1b8c2568fc92c7dfd_I20201231" decimals="-6" name="us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfOS0xMS0xLTEtMA_3fe66bff-fa9d-47b1-856c-6bb61698f3d8">30</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total other intangible assets</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:IdentifiableIntangibleAssetsGross" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMTAtMS0xLTEtMA_f111a8ec-9c9a-472d-abe0-d2de0e5d6a42">32,031</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:IdentifiableIntangibleAssetsAccumulatedAmortization" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMTAtMy0xLTEtMA_303f10e1-ceaa-4a99-885a-b0acb7fa3ddc">17,372</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:IntangibleAssetsNetExcludingGoodwill" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMTAtNS0xLTEtMA_5ad73002-69a6-42dd-af33-2f52964b0961">14,659</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="amgn:IdentifiableIntangibleAssetsGross" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMTAtNy0xLTEtMA_09086fd0-eaca-4c15-ac81-9068fbf27d36">32,048</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="amgn:IdentifiableIntangibleAssetsAccumulatedAmortization" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMTAtOS0xLTEtMA_825c73bb-c6d3-4392-828c-7e9587f06747">15,461</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:IntangibleAssetsNetExcludingGoodwill" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMTAtMTEtMS0xLTA_e48c27b7-7990-4794-bfbd-266e64fd46b9">16,587</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div></ix:nonNumeric><div style="text-align:justify;text-indent:22.5pt"><span><br/></span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Developed-product-technology rights consists of rights related to marketed products. Licensing rights primarily consists of contractual rights to receive future milestone, royalty and profit-sharing payments; capitalized payments to third parties for milestones related to regulatory approvals to commercialize products; and upfront payments associated with royalty obligations for marketed products. Marketing-related rights primarily consists of rights related to the sale and distribution of marketed products. R&amp;D technology rights pertains to technologies used in R&amp;D that have alternative future uses.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">IPR&amp;D consists of R&amp;D projects acquired in a business combination that are not complete at the time of acquisition due to remaining technological risks and/or lack of receipt of required regulatory approvals. We review IPR&amp;D projects for impairment annually, whenever events or changes in circumstances indicate that the carrying amounts may not be recoverable and upon the establishment of technological feasibility or regulatory approval.</span></div></ix:continuation><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">14</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"><ix:continuation id="i58b1ead60eba40a796f224c74dc0af05">During the three months ended September 30, 2021 and 2020, we recognized amortization associated with our finite-lived intangible assets of $<ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AmortizationOfIntangibleAssets" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTM5NA_8fdeada9-457a-46fe-ba87-12543bef952b">642</ix:nonFraction> million and $<ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AmortizationOfIntangibleAssets" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTQwMQ_7819d21d-ff0d-42d5-9bcc-0a5ffc419f73">708</ix:nonFraction> million, respectively. During the nine months ended September 30, 2021 and 2020, we recognized amortization associated with our finite-lived intangible assets of $<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:AmortizationOfIntangibleAssets" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTUzOQ_1e8aba80-5476-420c-a102-cf253040d380">1.9</ix:nonFraction> billion and $<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:AmortizationOfIntangibleAssets" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTU0Ng_1743b5e2-28dc-4286-816d-d4678cb2f12e">2.1</ix:nonFraction> billion, respectively. Amortization of intangible assets is primarily included in Cost of sales in the Condensed Consolidated Statements of Income. The total estimated amortization for our finite-lived intangible assets for the remaining three months ending December 31, 2021, and the years ending December 31, 2022, 2023, 2024, 2025 and 2026, are $<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTg2MQ_cdd99e9a-8eb8-40b2-bf42-9cbee61d5a00">0.6</ix:nonFraction> billion, $<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTg2NQ_82f691c2-5080-477f-8758-33673989a9e0">2.5</ix:nonFraction> billion, $<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTg2OQ_8dc92e32-a0de-4c77-a6bb-e4acfcf1e5f1">2.4</ix:nonFraction> billion, $<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTg3Mw_658ad877-a41d-4c55-a7a8-684a832596a4">2.4</ix:nonFraction> billion, $<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTg3Nw_42a2b487-16ae-4694-8ee1-27b47f088b8d">2.2</ix:nonFraction> billion and $<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTg4NA_67ad68ae-7036-46c0-9053-ed819513baa9">1.8</ix:nonFraction> billion, respectively.</ix:continuation></span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:18pt"><span><br/></span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">15</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_58"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">10. Financing arrangements</span></div><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:DebtDisclosureTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNzY2_68b740c1-43e6-486d-96b0-df99b867bee7" continuedAt="ic92f25fd8aaf47168d9300bfd9a753cf" escape="true"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:ScheduleOfDebtInstrumentsTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNzU5_7f3972f8-33f4-45dc-a2d8-d4e92ab8076b" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our borrowings consisted of the following (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:65.128%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.420%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.422%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i28a3a2e4d2f24ec1ab05429cee726f75_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMS0wLTEtMS0wL3RleHRyZWdpb246ZTlmMDViZTgxYjQwNGQ5MjlhNzE1NjQ4MWFmY2E1YmVfNA_f963eee7-74ee-4477-958e-7a5ca5e071f0">1.25</ix:nonFraction>% &#8364;<ix:nonFraction unitRef="eur" contextRef="i28a3a2e4d2f24ec1ab05429cee726f75_I20210930" decimals="INF" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentFaceAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMS0wLTEtMS0wL3RleHRyZWdpb246ZTlmMDViZTgxYjQwNGQ5MjlhNzE1NjQ4MWFmY2E1YmVfNw_1dc731b6-e1a1-4045-8da9-68b986f48726">1,250</ix:nonFraction> million notes due 2022 (1.25% 2022 euro Notes)</span></div></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i28a3a2e4d2f24ec1ab05429cee726f75_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMS0xLTEtMS0w_796a708e-3103-4188-a6df-f71ab366bf92">1,448</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1d8b35fb400b4d018ac1fc3ac92c4e11_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMS0zLTEtMS0w_406b4953-5e29-44e2-baf3-52b5d9cefe28">1,527</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="iba85a821e6d84b96a52fc42ef1b75604_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMi0wLTEtMS0wL3RleHRyZWdpb246MjBkZmZiZGFkYWE5NDJhMzhiYWNkNTYwZTViM2I1MzhfNA_a5bd67ab-1858-4ba4-8bf2-83e86a3fd1fc">2.70</ix:nonFraction>% notes due 2022 (2.70% 2022 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iba85a821e6d84b96a52fc42ef1b75604_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMi0xLTEtMS0w_5283a12e-da3d-448a-a54b-dcca3c519cf1">500</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia88d5a3b1b5c414db7ff8890b7c96f91_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMi0zLTEtMS0w_e3772fef-1987-4703-b07e-c713feedc9eb">500</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i1a04775f93b24e3c83787a805db33fd7_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMy0wLTEtMS0wL3RleHRyZWdpb246MWU3ZmQwMzZiMGM2NGI4Y2EyMmRmZmM5ZDQzZGY3ZDBfNA_aca13ab5-2234-4a19-9cde-827a25c90bc1">2.65</ix:nonFraction>% notes due 2022 (2.65% 2022 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1a04775f93b24e3c83787a805db33fd7_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMy0xLTEtMS0w_0f0857dd-5e77-4d91-81f5-cabd07f5d572">1,500</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i071cb4027c8549148b8bd96aea3e7c5c_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMy0zLTEtMS0w_070779e2-fb4d-4170-bd9c-0b9e504c36d1">1,500</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="ib744f296eafb4f8d88d2a38efb8a48a3_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNC0wLTEtMS0wL3RleHRyZWdpb246NTI2N2Q5NmUwZDEwNGEwZWEwYzgyODc1ZjVmMWNiZGVfNA_bdf1eaf9-2d91-486f-a028-f01c3f191771">3.625</ix:nonFraction>% notes due 2022 (3.625% 2022 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ib744f296eafb4f8d88d2a38efb8a48a3_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNC0xLTEtMS0w_1834e7b9-e9a5-4f80-9ed1-f174d4bf1217">750</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie50a52f9a64743be865aca69358499b2_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNC0zLTEtMS0w_5e1d6f1c-a22b-4e2c-908e-8c94a99bbcfd">750</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="id0d88ff8ca444d28a9d31155d2af6123_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNS0wLTEtMS0wL3RleHRyZWdpb246Nzc5MDUyOTE4NjRhNGNhYmFiZDgyNjM5OTRjN2I4NjVfNA_9759bd28-d6b1-442f-9601-e4c0dac5ac67">0.41</ix:nonFraction>% CHF<ix:nonFraction unitRef="chf" contextRef="id0d88ff8ca444d28a9d31155d2af6123_I20210930" decimals="INF" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentFaceAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNS0wLTEtMS0wL3RleHRyZWdpb246Nzc5MDUyOTE4NjRhNGNhYmFiZDgyNjM5OTRjN2I4NjVfNw_1c72fcf6-91c5-4ccb-bf1b-44bdb9dc8e20">700</ix:nonFraction> million bonds due 2023 (0.41% 2023 Swiss franc Bonds)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id0d88ff8ca444d28a9d31155d2af6123_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNS0xLTEtMS0w_b73fc250-973f-4f2a-97b3-417df60e425d">751</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iaccb7326e7d146e0aafad220d316b604_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNS0zLTEtMS0w_d069955f-193e-42db-a82f-bf1ab8309f21">791</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="id7b48ebaee8d4fddada565c9d549a4af_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNi0wLTEtMS0wL3RleHRyZWdpb246MmNiZTQxOGRjYTIxNGNlNDk1N2NjZGJjZDNkNzE4ZmNfNA_6343e35a-09e9-4cb0-9267-cd15d7075e17">2.25</ix:nonFraction>% notes due 2023 (2.25% 2023 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id7b48ebaee8d4fddada565c9d549a4af_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNi0xLTEtMS0w_edb10973-533d-4a23-893e-6efa8d5ab021">750</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id1e3e3f0ae1a4a3fb3b7e07bf050efd6_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNi0zLTEtMS0w_a2cdd1b3-5b05-4c0e-8bcb-4dd4aba0d90b">750</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i14cb17bbd31f41deb2c7c3feb4b40b34_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNy0wLTEtMS0wL3RleHRyZWdpb246NjE0NzdkNmZkN2M2NGY1YjlhZDhhN2FmODNhYTE1MGFfNA_e690b70a-99a4-4c23-8bfb-a844c444b26b">3.625</ix:nonFraction>% notes due 2024 (3.625% 2024 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i14cb17bbd31f41deb2c7c3feb4b40b34_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNy0xLTEtMS0w_90d72ab5-b3cc-4e39-988b-37b19f9a3b1b">1,400</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3f99f7b28ace4d3b80f5f9385a149eaf_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNy0zLTEtMS0w_1a9d2120-5769-4fee-9f6f-2fea0062f052">1,400</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i3e1c0c3571924fcf9795dd47036e02c4_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfOC0wLTEtMS0wL3RleHRyZWdpb246ZDVmNWI5ZDllOWU4NDQyMDhjZDBkZTBhNGU1ZTY1M2NfNA_df7845b6-b6ba-4339-a10e-c5bf11c05fbc">1.90</ix:nonFraction>% notes due 2025 (1.90% 2025 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3e1c0c3571924fcf9795dd47036e02c4_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfOC0xLTEtMS0w_dca8f5ac-59da-4b16-9799-5af92d282eb5">500</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1ad59cf770774b36883e5e3f187962e3_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfOC0zLTEtMS0w_316a70ff-2aee-4367-a9ed-cfb3a152f30b">500</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="ib8287a44e2c445c2acd186f4936f5772_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfOS0wLTEtMS0wL3RleHRyZWdpb246ZWQ1OGIyMDdjZTgzNGY1OGIwNTcwMzg2NzBkMzJmY2VfNA_283d3e6c-0d5c-4f8b-8b26-ba7e896555dc">3.125</ix:nonFraction>% notes due 2025 (3.125% 2025 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ib8287a44e2c445c2acd186f4936f5772_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfOS0xLTEtMS0w_959da130-c4e2-42a0-8669-3b37943c165e">1,000</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i6be009b691aa4576ac79c8915e21298d_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfOS0zLTEtMS0w_2450afa1-9f7e-465b-8eee-8f7af87b23d1">1,000</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i35556fe1ea36409196d95de0bec85fae_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTAtMC0xLTEtMC90ZXh0cmVnaW9uOjZmZWM0ODA3OWI0YjRiNzBhNjIzNjVlZGM0ZDU4YjU4XzQ_4e7fa11c-cacd-4639-86bf-9f25e11c96fc">2.00</ix:nonFraction>% &#8364;<ix:nonFraction unitRef="eur" contextRef="i35556fe1ea36409196d95de0bec85fae_I20210930" decimals="INF" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentFaceAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTAtMC0xLTEtMC90ZXh0cmVnaW9uOjZmZWM0ODA3OWI0YjRiNzBhNjIzNjVlZGM0ZDU4YjU4Xzc_51e6df80-2eb4-4235-850b-93fbf60c1374">750</ix:nonFraction> million notes due 2026 (2.00% 2026 euro Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i35556fe1ea36409196d95de0bec85fae_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTAtMS0xLTEtMA_92539352-146d-4f3d-8366-9da993612d69">869</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iee3ca7ca07cc4b1b82dc3946ebca7fda_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTAtMy0xLTEtMA_eb310170-0ae0-4fe6-8e47-c6b9b8a13b5f">916</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i52dee93b650b4cd8868ed20f7cf964bc_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTEtMC0xLTEtMC90ZXh0cmVnaW9uOjIwN2M0Y2ViMzE1NDQ0MDQ4MzNhZjI2MjRkMzBjYTZhXzQ_7498db3e-5eb1-47c6-b324-8e2ac7fb2732">2.60</ix:nonFraction>% notes due 2026 (2.60% 2026 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i52dee93b650b4cd8868ed20f7cf964bc_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTEtMS0xLTEtMA_f6b35400-741b-472b-91c2-27a2441bff48">1,250</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i98166ba2f34643ffafa2e088bf573187_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTEtMy0xLTEtMA_f9a59548-94a7-4837-8f96-37ec3074e60f">1,250</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="ib9a2ddc95a504747aa69a99a4d875fea_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTItMC0xLTEtMC90ZXh0cmVnaW9uOjU5ZWQ4MDRhZjViMTQyZTdiZjg1MTQ3ZjgyNjBkMjQ3XzQ_a1f4a18b-56c4-4bc7-86ac-86ecec6cd778">5.50</ix:nonFraction>% &#163;<ix:nonFraction unitRef="gbp" contextRef="ib9a2ddc95a504747aa69a99a4d875fea_I20210930" decimals="INF" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentFaceAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTItMC0xLTEtMC90ZXh0cmVnaW9uOjU5ZWQ4MDRhZjViMTQyZTdiZjg1MTQ3ZjgyNjBkMjQ3Xzc_0ba14d0f-766b-4569-a2da-bfe87f70dc81">475</ix:nonFraction> million notes due 2026 (5.50% 2026 pound sterling Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ib9a2ddc95a504747aa69a99a4d875fea_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTItMS0xLTEtMA_3d7b72e8-3667-4ea0-98e6-ba80e12265eb">640</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic87056a5fa024aba8b55cbd31c06353a_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTItMy0xLTEtMA_e37654ef-42d9-4728-b507-9e2840255311">649</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i5285c4d278d54713b60c0cc0f87aa46a_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTMtMC0xLTEtMC90ZXh0cmVnaW9uOjJlY2Y0MjQzM2IxYTQzNDM5NGE4MjFhNmFlOGZjNzIxXzQ_b1e08b8c-47a3-4b68-a8f0-c5dea1833b63">2.20</ix:nonFraction>% notes due 2027 (2.20% 2027 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5285c4d278d54713b60c0cc0f87aa46a_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTMtMS0xLTEtMA_9206508c-ecdd-480d-be02-5d9e70dcb831">1,750</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i6bb96c6e9f4048dfa94c91a4ab648b6a_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTMtMy0xLTEtMA_de906531-c75a-4390-8362-dc1afb7eba4d">1,750</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i705890d8cae541638f21f7669dbe4b04_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTQtMC0xLTEtMC90ZXh0cmVnaW9uOmEzYjczY2E0NDZhMzQ4ZjJhNzZiZmY2YjVlY2JiMjlkXzQ_ea5cb5db-e0fc-4969-a7f3-e558df922eba">3.20</ix:nonFraction>% notes due 2027 (3.20% 2027 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i705890d8cae541638f21f7669dbe4b04_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTQtMS0xLTEtMA_a5b7a7e1-ac67-4fcd-be5a-fb2f3b41a08e">1,000</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ieb62499093c345529236e71f444d0853_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTQtMy0xLTEtMA_30f7945b-809f-4510-a49b-772c602720e1">1,000</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="ibda3099c78a845a98d23ce711d8447f6_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTUtMC0xLTEtNDk1OS90ZXh0cmVnaW9uOmMzNjBkMDA2ZGE1YTQ4NTc4N2M4YjQ0ZjZmODFkMzhjXzc2OTY1ODEzOTQ0ODI_fff2d3a5-3aa1-4bec-a367-54dfa44096da">1.65</ix:nonFraction>% note due 2028 (1.65% 2028 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ibda3099c78a845a98d23ce711d8447f6_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTUtMS0xLTEtNTE0Mw_8372be6c-69ad-4f6f-b86d-25f0e8fd9b56">1,250</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ibb2e9e5c4f2a4bbf841a6bc671651b19_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTUtMy0xLTEtNTE0Mw_5ded548a-54a1-458a-84a8-b794bd8fa9d4">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i407ab77f9d0440acae9fe2fc19c63542_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTUtMC0xLTEtMC90ZXh0cmVnaW9uOjlhZjQxMTQ4MGUzZTRhZDNiYzUyYmFmYmVhMTMzOTkxXzQ_2e1e3d48-61a2-4f5f-8ba7-3c4226993a4c">4.00</ix:nonFraction>% &#163;<ix:nonFraction unitRef="gbp" contextRef="i407ab77f9d0440acae9fe2fc19c63542_I20210930" decimals="INF" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentFaceAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTUtMC0xLTEtMC90ZXh0cmVnaW9uOjlhZjQxMTQ4MGUzZTRhZDNiYzUyYmFmYmVhMTMzOTkxXzc_642d70c5-e7f3-458b-ad26-b95a91199a22">700</ix:nonFraction> million notes due 2029 (4.00% 2029 pound sterling Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i407ab77f9d0440acae9fe2fc19c63542_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTUtMS0xLTEtMA_b5437edc-bc52-4252-8a5f-91c8df51a50c">943</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i000f9a5c0b8f4cd99faa556d2ea850e6_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTUtMy0xLTEtMA_46efea7c-cbea-44a3-8805-14e4f2731e95">957</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="ia3569d0c6bcd4203a1148cb8dda584fe_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTYtMC0xLTEtMC90ZXh0cmVnaW9uOjdkZTc0NTZjNGQzZTRmNDY5ZDVjYzEyMzk0ZWUxNDc0XzQ_36870ca1-3750-417f-acc7-dfac96f50a42">2.45</ix:nonFraction>% notes due 2030 (2.45% 2030 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia3569d0c6bcd4203a1148cb8dda584fe_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTYtMS0xLTEtMA_83aede98-2ccb-461a-9a12-013123ff344f">1,250</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id46fc442a7f34ba2afc285c190d4a3c5_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTYtMy0xLTEtMA_64670b3c-da24-4c7d-964d-2fbada459a85">1,250</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i2c54babb8e9f4eb8b43722a88181da66_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTctMC0xLTEtMC90ZXh0cmVnaW9uOjVhZGRkNTJiMzNiMDQ1NjU4NGQ2YmJmNDMyMWYzYTZjXzQ_19c0ff62-066b-4d05-89aa-a17d82a0507e">2.30</ix:nonFraction>% notes due 2031 (2.30% 2031 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2c54babb8e9f4eb8b43722a88181da66_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTctMS0xLTEtMA_f6607fb1-7d64-4e29-9022-fe1a598139e3">1,250</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2f896bd90bd24cfcbf6f31271e9148e9_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTctMy0xLTEtMA_246f6ca7-f163-41c4-bc6e-05d6060a630f">1,250</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i220407dac7c34df4809bfc677b8b3503_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTktMC0xLTEtNTYwNC90ZXh0cmVnaW9uOjI4MmJhNTYzNzgwZjQ5MWY4MDMxZjE4MDIxOGU3MGQwXzgyNDYzMzcyMDgzNjg_99fb8d5e-31f8-4ccd-8041-61c4ae49de70">2.00</ix:nonFraction>% notes due 2032 (2.00% 2032 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i220407dac7c34df4809bfc677b8b3503_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTktMS0xLTEtNTA4OA_26b5c033-93d9-4745-b928-57c79b517d3a">1,250</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i10faa7c13c3447bbbc7cfae536e3c802_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTgtMC0xLTEtMC90ZXh0cmVnaW9uOmQ4MDVmNGRlMmM2YzQ1ODk5NGY2N2M1NGJhNzNlMGNkXzQ_8afc6e19-1c59-480d-a69b-bf8f2a9b31c3">6.375</ix:nonFraction>% notes due 2037 (6.375% 2037 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i10faa7c13c3447bbbc7cfae536e3c802_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTgtMS0xLTEtMA_a9c52a8f-15f2-4859-9fa5-f5b9e9a5953c">478</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia6787d1b183a4eaf8408dbce1815a07c_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTgtMy0xLTEtMA_b8098161-bb75-43ee-ad81-9fb864a9ea7d">478</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="iac7d798f49894466bc42c0153cdf0595_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTktMC0xLTEtMC90ZXh0cmVnaW9uOmE1MWU1OTIzMzYwMTQxMjVhMTIxOTEzZTQ4MjY4NjkxXzQ_c3fb5360-a220-432b-b55f-5f9ef922292e">6.90</ix:nonFraction>% notes due 2038 (6.90% 2038 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iac7d798f49894466bc42c0153cdf0595_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTktMS0xLTEtMA_126301c0-a107-40ef-af50-7a0972911e22">254</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ib5e6389f8cf6478dbebef3136cee8c23_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTktMy0xLTEtMA_3b3a4b44-f141-4df6-84ba-a9eaf180b9ea">254</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i512d102f92cd4cc2833291c7e8cd520d_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjAtMC0xLTEtMC90ZXh0cmVnaW9uOjczY2JiYTliMTE0MTQzNDRiY2FiMzdiZDVlYzQ2YWRjXzQ_ee31a9e9-db6a-4dca-bcd4-122991d8ec78">6.40</ix:nonFraction>% notes due 2039 (6.40% 2039 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i512d102f92cd4cc2833291c7e8cd520d_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjAtMS0xLTEtMA_68641350-ad6d-45d7-acce-564b90f581fb">333</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i6af736050aa24649ab1cfff13dee1b92_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjAtMy0xLTEtMA_536290b3-9f19-4a92-8cc1-a3669af63408">333</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i99981976037d4cef90e95f33441854b2_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjEtMC0xLTEtMC90ZXh0cmVnaW9uOjkxZjE1ZjdmMTIzNDQ1NmJhNTIwYzkwYWU0N2JhY2NiXzQ_7387450e-c06e-4384-96fd-0300111dcc23">3.15</ix:nonFraction>% notes due 2040 (3.15% 2040 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i99981976037d4cef90e95f33441854b2_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjEtMS0xLTEtMA_190c671a-72ba-411a-b5c2-f17c84a56438">2,000</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id540a747481347329775d9396bb889d2_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjEtMy0xLTEtMA_34349e7f-763d-4778-a7c3-991ac4099596">2,000</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i00fb0934241248439eae35efb4b7888e_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjItMC0xLTEtMC90ZXh0cmVnaW9uOmYxMjg4NWVjZWY0ZjQwYTE5MDEwYjFhMWZiMjg3NTQzXzQ_9b414dfc-b537-4c26-b559-da542f4513c0">5.75</ix:nonFraction>% notes due 2040 (5.75% 2040 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i00fb0934241248439eae35efb4b7888e_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjItMS0xLTEtMA_e4299913-0d7b-47b3-b125-199c88f54be5">373</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ib61d19755e0742c09a249871a640ecd1_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjItMy0xLTEtMA_e5256e6f-4046-44d3-951c-5ddee1c78c96">373</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="id14f137f4c5e454687d4fbce9656c938_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjUtMC0xLTEtNTI1Ni90ZXh0cmVnaW9uOjc0YzcxNjE2ZjQ2YTRmZGQ4OWVhN2NjYWI3NWU5MGNhXzc2OTY1ODEzOTQ0Nzk_71f1018d-9c22-4f62-bc85-dd25c1b00215">2.80</ix:nonFraction>% note due 2041 (2.80% 2041 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id14f137f4c5e454687d4fbce9656c938_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjUtMS0xLTEtNTA1NA_6144ef09-7a10-4308-b6f0-56c10a50fa7d">1,150</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="id4a29b7b702446d0b6a2302a87559c9a_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjMtMC0xLTEtMC90ZXh0cmVnaW9uOjM2YmYxZDRlM2NlMDRmYWQ5OGE5MjNiMGEwNGM3NTllXzQ_846d996c-bcb4-4019-9643-7a6e814d1e99">4.95</ix:nonFraction>% notes due 2041 (4.95% 2041 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id4a29b7b702446d0b6a2302a87559c9a_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjMtMS0xLTEtMA_05c75ab9-6c35-4662-ad65-7ee2d5d445d6">600</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i891f05772784463faf20ad97f433010d_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjMtMy0xLTEtMA_eb1a2930-48f2-4b98-9462-30a1b4023447">600</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i1175ce0d1778434ab2f82d1aeb58bf2e_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjQtMC0xLTEtMC90ZXh0cmVnaW9uOjFmZTUxMGUxZjY3OTQzYTRhYWViNTU3M2RlMjRhOGIyXzQ_4ac5cb80-1afb-4396-995a-f21ed9928658">5.15</ix:nonFraction>% notes due 2041 (5.15% 2041 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1175ce0d1778434ab2f82d1aeb58bf2e_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjQtMS0xLTEtMA_2a756784-696c-473f-ba2f-cdb408417149">729</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iad10456565dc49e7bc078124e8cd8fe1_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjQtMy0xLTEtMA_d410481d-7753-4b21-b608-036c7db49f1c">729</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="ia5815daee6a4476eba6259b8d47fe654_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjUtMC0xLTEtMC90ZXh0cmVnaW9uOjUxZjViN2QzZTQyODRlNmQ5MTJlZGQ0ZmEwNzJkNGQyXzQ_144bd1aa-0ea9-4dcb-9feb-b6d08cad4dde">5.65</ix:nonFraction>% notes due 2042 (5.65% 2042 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia5815daee6a4476eba6259b8d47fe654_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjUtMS0xLTEtMA_da989ebd-b4f9-4912-a048-3ec258be5b0e">415</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5dfbce0b73c242c8baa5ce827dad9a2c_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjUtMy0xLTEtMA_7dfe5b2c-6c17-4dec-83cc-f80b3db1b294">415</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="if7316ee9f235452f8616207596971771_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjYtMC0xLTEtMC90ZXh0cmVnaW9uOjYzZWEyZGNjZWY0ZjQzMDU4NDc3ZjI0NjMwNjU1Yzc4XzQ_c1c1094b-13c8-426a-a71e-b356cb25a998">5.375</ix:nonFraction>% notes due 2043 (5.375% 2043 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if7316ee9f235452f8616207596971771_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjYtMS0xLTEtMA_39f32e99-d985-42fe-beed-c863a10a4fd5">185</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1675c34a9e9f402db5c00ceb852bb0b6_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjYtMy0xLTEtMA_5c7602ba-8bb7-4e7f-b553-2ad72c605e6f">185</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i0fd6f6c0e19b45a0b4db95bced8c11a2_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjctMC0xLTEtMC90ZXh0cmVnaW9uOmIwMTRjODdiYzkyYzQ4ODhiOGFiYzZkMTJmMTcyMjI1XzQ_8272cc84-1541-43f4-b56e-981a4d768257">4.40</ix:nonFraction>% notes due 2045 (4.40% 2045 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i0fd6f6c0e19b45a0b4db95bced8c11a2_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjctMS0xLTEtMA_5b9bde14-2f98-4b99-b15e-fc9b8736bad6">2,250</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i93a7eb973f5245969d84a7be7e597722_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjctMy0xLTEtMA_f7b9f2cc-f87e-4c15-92fd-17e17306dfc7">2,250</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="ied462f3ca0734341b45ec582dc99c7cf_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjgtMC0xLTEtMC90ZXh0cmVnaW9uOmQ4YTc1ZDQ4YTZkOTQwYjVhYjQzZTJjMDJjNGMzMWQwXzQ_2dd28c99-e34a-4f2b-be59-4dbd9c6323c8">4.563</ix:nonFraction>% notes due 2048 (4.563% 2048 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ied462f3ca0734341b45ec582dc99c7cf_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjgtMS0xLTEtMA_b0f44ddb-3ee2-4910-94fb-542d2d1d4128">1,415</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3a969d07d31f43ee8b8793eb8498e57b_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjgtMy0xLTEtMA_6bd1fa3a-75c7-4936-9127-d86dc82839a9">1,415</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i27a15eba71944c9f9d27a09b187b5445_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjktMC0xLTEtMC90ZXh0cmVnaW9uOmY1OWE4ZTk5NjVmODQ5MTBiYmNjYTBlZTBjODU5NDJjXzQ_88e82543-827a-4aa9-b894-9eec41231d89">3.375</ix:nonFraction>% notes due 2050 (3.375% 2050 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i27a15eba71944c9f9d27a09b187b5445_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjktMS0xLTEtMA_69acfbeb-6ec8-4045-ab86-f737afa40e40">2,250</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if178d7d786ea47c094645c6a4aac66f9_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjktMy0xLTEtMA_32946b2b-4902-4adb-a356-922d29256f25">2,250</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="iceaad247ba05416ca273ec699ead3eb8_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzAtMC0xLTEtMC90ZXh0cmVnaW9uOmI1NmM5YzVmOGM3MzRlOGQ5MmM0MjA3NWU5Zjc5ODkxXzQ_99a5a96d-7b93-46c5-a8ee-f1ef98206546">4.663</ix:nonFraction>% notes due 2051 (4.663% 2051 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iceaad247ba05416ca273ec699ead3eb8_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzAtMS0xLTEtMA_848ba306-22ad-4f97-9e06-17a38ed7e5f4">3,541</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i36d572d0be7b4f45b4a95c96ad590314_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzAtMy0xLTEtMA_ca964c8f-583d-4733-b92b-8cc21a6be290">3,541</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i2471f208310742da8d39936484269aa5_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzQtMC0xLTEtNTMyNi90ZXh0cmVnaW9uOmM1NjM0NDQ4MmI5NzQwZWNhMTk5ZTAwZjViOGMzZjYwXzgyNDYzMzcyMDgzODM_03f6d8ac-1c01-4d69-a500-d42bc5d680d4">3.00</ix:nonFraction>% notes due 2052 (3.00% 2052 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2471f208310742da8d39936484269aa5_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzQtMS0xLTEtNTI5NA_f7372b76-78a7-4684-a034-06b589c41c3b">1,350</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iabc69f9b3f0d4959883895ba0b604099_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzQtMy0xLTEtNTI5NA_017902f7-f81d-4882-9bad-ebf8229d4d89">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="iab6eca48d1b2444986c10a3c8b80b044_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzEtMC0xLTEtMC90ZXh0cmVnaW9uOjZiZTk5YmEwZGQ0NzQzYjA5MzFhMTkyNzliZjc0OGM2XzQ_c83e1a0f-284e-4d1d-a871-3b1a7cd2e92f">2.77</ix:nonFraction>% notes due 2053 (2.77% 2053 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iab6eca48d1b2444986c10a3c8b80b044_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzEtMS0xLTEtMA_7f064546-33c2-4148-89d8-753fd514b168">940</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if155164e9eda4b7494a946338f4c79fb_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzEtMy0xLTEtMA_d6df2351-b2fa-4e69-a448-20608505044c">940</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other notes due 2097</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i33b3f55471c04aefa2d6d4d4486a0ee1_I20210930" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzItMS0xLTEtMA_ccf01916-1f1f-4c31-a302-6bc108b5025f">100</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i98d314d0c5ac49429ee3c71c38d086dc_I20201231" decimals="-6" name="us-gaap:DebtInstrumentCarryingAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzItMy0xLTEtMA_b641f4de-4a5d-4422-a6f5-793638a497b6">100</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Unamortized bond discounts, premiums and issuance costs, net</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzMtMS0xLTEtMA_1505cf53-6498-486f-92fa-05cd0613acb2">1,221</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzMtMy0xLTEtMA_54400ff0-afa4-4655-97aa-d212d4212c3d">1,188</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Fair value adjustments</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" name="us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzQtMS0xLTEtMA_9f1c374e-f3c3-424b-a7da-19dc3441c568">371</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" name="us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzQtMy0xLTEtMA_0e8855e7-df99-41a9-af6f-8f8cf81d34d5">566</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" name="us-gaap:OtherLongTermDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzUtMS0xLTEtMA_228adf5f-99fa-413e-ad70-f7bf23a95a78">15</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" name="us-gaap:OtherLongTermDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzUtMy0xLTEtMA_2d3c1714-bff6-4614-b3ba-1c1243c4f1a6">5</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total carrying value of debt</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:LongTermDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzYtMS0xLTEtMA_75b1d747-c5ba-4c2b-a63f-dde375434b3b">37,579</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:LongTermDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzYtMy0xLTEtMA_7e9c9d82-cca2-4ae6-8631-085091185199">32,986</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Less current portion</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:LongTermDebtCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzctMS0xLTEtMA_e0005307-96b7-4dae-9289-07cd440927e5">4,288</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" name="us-gaap:LongTermDebtCurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzctMy0xLTEtMA_3609a304-6d79-4c58-a0b7-85ccfe4655e6">91</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total long-term debt</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:LongTermDebtNoncurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzgtMS0xLTEtMA_54904d7f-1b43-454c-bc6c-435c2e88f22a">33,291</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:LongTermDebtNoncurrent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzgtMy0xLTEtMA_031214c2-5b1e-408f-a6ef-f148f08a1dd3">32,895</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div></ix:nonNumeric><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">There are no material differences between the effective interest rates and coupon rates of any of our borrowings, except for the <ix:nonFraction unitRef="number" contextRef="ied462f3ca0734341b45ec582dc99c7cf_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfMjAw_1dbf7d78-99fc-45f2-9abe-9d1583d4f68b">4.563</ix:nonFraction>% 2048 Notes, the <ix:nonFraction unitRef="number" contextRef="iceaad247ba05416ca273ec699ead3eb8_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfMjE5_5c058352-7dd2-41b2-90a0-b057abafdad7">4.663</ix:nonFraction>% 2051 Notes and the <ix:nonFraction unitRef="number" contextRef="iab6eca48d1b2444986c10a3c8b80b044_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfMjQx_907f6496-04e8-4e9b-8124-6ea02c0c579a">2.77</ix:nonFraction>% 2053 Notes, which have effective interest rates of <ix:nonFraction unitRef="number" contextRef="ied462f3ca0734341b45ec582dc99c7cf_I20210930" decimals="3" name="us-gaap:DebtInstrumentInterestRateEffectivePercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfMjk1_9b61b314-09f0-4c56-b1ef-3945f5926d1a">6.3</ix:nonFraction>%, <ix:nonFraction unitRef="number" contextRef="iceaad247ba05416ca273ec699ead3eb8_I20210930" decimals="3" name="us-gaap:DebtInstrumentInterestRateEffectivePercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfMjk5_b1da27f5-1b1c-442c-93cc-244e404e43b5">5.6</ix:nonFraction>% and <ix:nonFraction unitRef="number" contextRef="iab6eca48d1b2444986c10a3c8b80b044_I20210930" decimals="3" name="us-gaap:DebtInstrumentInterestRateEffectivePercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfMzA2_95a00e2a-ca08-4f0b-8658-0c78caa3d21c">5.2</ix:nonFraction>%, respectively.</span></div></ix:nonNumeric><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">16</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><ix:continuation id="ic92f25fd8aaf47168d9300bfd9a753cf"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">During the three months ended September 30, 2021, we issued $<ix:nonFraction unitRef="usd" contextRef="i33a19bf9151948efb174bed3a79387f0_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentFaceAmount" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDE4MA_c0a8a75a-182e-4bbf-9e5d-c192b5e5d229">5.0</ix:nonFraction>&#160;billion of debt consisting of $<ix:nonFraction unitRef="usd" contextRef="ibda3099c78a845a98d23ce711d8447f6_I20210930" decimals="-7" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentFaceAmount" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDE5NA_9cf4d702-4e57-4ab1-803d-29b8d40f0765">1.25</ix:nonFraction>&#160;billion of the <ix:nonFraction unitRef="number" contextRef="ibda3099c78a845a98d23ce711d8447f6_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI2Mg_7ca8ca61-6341-42aa-8770-01422f4e9e6f">1.65</ix:nonFraction>% 2028 Notes, $<ix:nonFraction unitRef="usd" contextRef="i220407dac7c34df4809bfc677b8b3503_I20210930" decimals="-7" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentFaceAmount" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDIwOQ_c559cc56-2218-40ef-b618-0391c551266e">1.25</ix:nonFraction>&#160;billion of the <ix:nonFraction unitRef="number" contextRef="i220407dac7c34df4809bfc677b8b3503_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI2OQ_78f0a80e-7f84-4106-8150-b5a86542708d">2.00</ix:nonFraction>% 2032 Notes, $<ix:nonFraction unitRef="usd" contextRef="id14f137f4c5e454687d4fbce9656c938_I20210930" decimals="-7" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentFaceAmount" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDIyNA_53c36fd9-6b28-4385-b699-d66eef7c1c6d">1.15</ix:nonFraction>&#160;billion of the <ix:nonFraction unitRef="number" contextRef="id14f137f4c5e454687d4fbce9656c938_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI3Ng_544741ec-c393-489c-9a2f-29739bc02373">2.80</ix:nonFraction>% 2041 Notes and $<ix:nonFraction unitRef="usd" contextRef="i2471f208310742da8d39936484269aa5_I20210930" decimals="-7" format="ixt:num-dot-decimal" name="us-gaap:DebtInstrumentFaceAmount" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDIzOQ_0b94350f-d524-485b-b4a9-ecf5fbf96cd5">1.35</ix:nonFraction>&#160;billion of the <ix:nonFraction unitRef="number" contextRef="i2471f208310742da8d39936484269aa5_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI4OQ_4f1427d4-3fba-4223-825d-be754be3d716">3.00</ix:nonFraction>% 2052 Notes. In the event of a change-in-control triggering event, as defined in the terms of the notes, we may be required to purchase all or a portion of these notes at a price equal to <ix:nonFraction unitRef="number" contextRef="ifc54ee979f3c450d94595dd648269176_D20210701-20210930" decimals="INF" name="amgn:PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI1NA_523f8b87-41a8-4243-8997-346eaaf5a1ba"><ix:nonFraction unitRef="number" contextRef="id79db748ed1c48398fe671a31ee535e0_D20210701-20210930" decimals="INF" name="amgn:PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI1NA_8efd579b-8c61-405e-945b-acb09ffd342c"><ix:nonFraction unitRef="number" contextRef="ie5587a9964dd43d2a6782cd812ea6608_D20210701-20210930" decimals="INF" name="amgn:PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI1NA_d247c102-5c07-40cf-a58c-c27290fdb4c4"><ix:nonFraction unitRef="number" contextRef="ic6452876c4b84f979e9f7d07007ec855_D20210701-20210930" decimals="INF" name="amgn:PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI1NA_e438867d-d6eb-44a1-b7ec-d97501bb5c04">101</ix:nonFraction></ix:nonFraction></ix:nonFraction></ix:nonFraction>% of the principal amount of the notes plus accrued and unpaid interest. In addition, these notes may be redeemed at any time at our option, in whole or in part, at the principal amount of the notes being redeemed plus accrued and unpaid interest and a make-whole amount, which are defined by the terms of the notes. The notes may be redeemed without payment of make-whole amounts if redemption occurs during a specified period of time immediately prior to the maturing of the notes. Such time periods range from <ix:nonNumeric contextRef="ia312c6387bbf40488704796f2339d92c_D20210101-20210930" format="ixt-sec:durwordsen" name="amgn:DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNzY5NjU4MTM5NjQyNQ_d8fef177-0654-43f4-b3c1-9ffc7948772a">two months</ix:nonNumeric> to <ix:nonNumeric contextRef="ic5275f5bc2cf4d60a35166b9ec79a4c2_D20210101-20210930" format="ixt-sec:durwordsen" name="amgn:DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNzY5NjU4MTM5NjQ0NA_66de48cb-dc1a-407e-819b-0341a229fe7f">six months</ix:nonNumeric> prior to maturity.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">During the three months ended June 30, 2021, we entered into the following interest rate swap contracts: (i) $<ix:nonFraction unitRef="usd" contextRef="ia3569d0c6bcd4203a1148cb8dda584fe_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:DerivativeNotionalAmount" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNDMz_b801bc97-a129-418a-a4d3-7b9efb4a7f41">1.0</ix:nonFraction>&#160;billion notional amount with respect to the <ix:nonFraction unitRef="number" contextRef="ia3569d0c6bcd4203a1148cb8dda584fe_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNDcy_d53bfa8f-f466-4f22-b676-29401cd1b010">2.45</ix:nonFraction>% 2030 Notes, resulting in an effective interest rate of three-month LIBOR plus <ix:nonFraction unitRef="number" contextRef="i434c36284fce4b0fb4ec413faf8330f4_I20210930" decimals="INF" name="us-gaap:DerivativeBasisSpreadOnVariableRate" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNTUz_435f1626-0fe2-4338-a7f3-c47f04d7c4d1">1.0</ix:nonFraction>% for that portion of the notes, and (ii) $<ix:nonFraction unitRef="usd" contextRef="i2c54babb8e9f4eb8b43722a88181da66_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DerivativeNotionalAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNTk2_10aee310-d44d-433b-9e55-f30bfbaa3e49">500</ix:nonFraction>&#160;million notional amount with respect to the <ix:nonFraction unitRef="number" contextRef="i2c54babb8e9f4eb8b43722a88181da66_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNjM1_d2829941-42ab-4106-9280-da3ec52d15d2">2.30</ix:nonFraction>% 2031 Notes, resulting in an effective interest rate of three-month LIBOR plus <ix:nonFraction unitRef="number" contextRef="i4eb0394fe4684ccdb9a301bd5115028c_I20210930" decimals="INF" name="us-gaap:DerivativeBasisSpreadOnVariableRate" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNzE2_b58f9b40-0598-4043-8cce-926423078087">0.8</ix:nonFraction>% for that portion of the notes.</span></div></ix:continuation><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">17</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_61"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">11. <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:StockholdersEquityNoteDisclosureTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfOTQz_fac6f2be-d626-4298-b51f-75344d6c4633" continuedAt="ie590cd7159a54ab9a6b1acfea4d97d2a" escape="true">Stockholders&#8217; equity</ix:nonNumeric></span></div><ix:continuation id="ie590cd7159a54ab9a6b1acfea4d97d2a" continuedAt="ie3fda48d8ee546a5918b4be787391818"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Stock repurchase program</span></div><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="amgn:StockRepurchaseProgramTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfOTcy_94d14ea9-0d35-4fe1-b042-4a730f15cc91" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Activity under our stock repurchase program, on a trade date basis, was as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:42.321%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.496%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.496%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.496%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.501%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Shares</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Dollars&#160;</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Shares</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Dollars</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">First quarter</span></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331" decimals="-5" name="us-gaap:StockRepurchasedDuringPeriodShares" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMi0xLTEtMS0w_ca5a1e39-e71e-4b8a-8079-73702ef424dd">3.7</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331" decimals="-6" name="us-gaap:StockRepurchasedDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMi0zLTEtMS0w_aa42f987-10c5-4128-b722-12ee1296fee8">865</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331" decimals="-5" name="us-gaap:StockRepurchasedDuringPeriodShares" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMi01LTEtMS0w_f49c153a-b48e-4af3-9d54-173fa30e2c54">4.3</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331" decimals="-6" name="us-gaap:StockRepurchasedDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMi03LTEtMS0w_9e858b14-8fec-48de-9ddf-c52b47e49105">933</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Second quarter</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630" decimals="-5" name="us-gaap:StockRepurchasedDuringPeriodShares" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMy0xLTEtMS0w_cc374c76-90ad-4a14-88ea-e312ef0fbca7">6.5</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockRepurchasedDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMy0zLTEtMS0w_6b5067da-27e3-4068-8e29-4ba60f748599">1,592</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630" decimals="-5" name="us-gaap:StockRepurchasedDuringPeriodShares" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMy01LTEtMS0w_bbeb536d-8a9f-4176-a625-53fe8995d143">2.6</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630" decimals="-6" name="us-gaap:StockRepurchasedDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMy03LTEtMS0w_531990b4-1b2e-4973-a79e-a568d896e7bb">591</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Third quarter</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-5" name="us-gaap:StockRepurchasedDuringPeriodShares" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNC0xLTEtMS0w_442eaedc-03e0-4e72-9a34-f7c167c7f728">4.6</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockRepurchasedDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNC0zLTEtMS0w_644d31f0-9954-477c-a7c6-da2f23799bd7">1,069</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-5" name="us-gaap:StockRepurchasedDuringPeriodShares" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNC01LTEtMS0w_57556fdc-4378-40db-aa5f-f0e32077c4d3">3.0</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:StockRepurchasedDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNC03LTEtMS0w_89514413-4223-410c-9fb6-8ef05f5c4423">752</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total stock repurchases</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-5" name="us-gaap:StockRepurchasedDuringPeriodShares" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNS0xLTEtMS0w_90a3cbc3-05fb-4107-a7fb-abbd25661de7">14.8</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockRepurchasedDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNS0zLTEtMS0w_5a6f8b24-ae49-4c8a-9e5d-c8a6d0348ac1">3,526</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="shares" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-5" name="us-gaap:StockRepurchasedDuringPeriodShares" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNS01LTEtMS0w_f2e761d0-bad2-4a21-9a83-1d500c772b45">9.9</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:StockRepurchasedDuringPeriodValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNS03LTEtMS0w_81ece32a-43d9-4ca6-a243-ad7e595d83ed">2,276</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div></ix:nonNumeric><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In March 2021, our Board of Directors increased the amount authorized under our stock repurchase program by an additional $<ix:nonFraction unitRef="usd" contextRef="ibb4ad07750104a41ad551ce7e97f7afe_I20210630" decimals="INF" format="ixt:num-dot-decimal" name="us-gaap:StockRepurchaseProgramAuthorizedAmount1" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMjYw_7623c9a3-1e10-40ee-8bb7-bd8e28a65919">3.4</ix:nonFraction>&#160;billion. As of September 30, 2021</span><span style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, $<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMjc0_131744ca-df23-4c02-9bf5-130663d736bc">2.9</ix:nonFraction> billion of aut</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">horization remained available under our stock repurchase program. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In October 2021, the Board of Directors increased the amount authorized under our stock repurchase program by an additional $4.5 billion.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Dividends</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In July 2021, March 2021 and December 2020, the Board of Directors declared a quarterly cash dividend of $<ix:nonFraction unitRef="usdPerShare" contextRef="i461e1d1d258d4b4faf9c477a92b85a30_D20210301-20210331" decimals="2" name="us-gaap:CommonStockDividendsPerShareDeclared" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODkzMA_3d65cc63-894e-420a-9b4f-8ecd23f94939"><ix:nonFraction unitRef="usdPerShare" contextRef="iccfbc695297d4e6b87ea624adb1a3149_D20210901-20210930" decimals="2" name="us-gaap:CommonStockDividendsPerShareCashPaid" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODkzMA_5fdf3cc6-226f-4d8b-a4eb-daea7fa6fcc0"><ix:nonFraction unitRef="usdPerShare" contextRef="ib619731edd7541fe8568acd19da059d6_D20210601-20210630" decimals="2" name="us-gaap:CommonStockDividendsPerShareCashPaid" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODkzMA_640734ac-be18-46f8-99fd-f5ee46d66cee"><ix:nonFraction unitRef="usdPerShare" contextRef="i461e1d1d258d4b4faf9c477a92b85a30_D20210301-20210331" decimals="2" name="us-gaap:CommonStockDividendsPerShareCashPaid" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODkzMA_7fad2c34-0697-4b09-a8cf-4f8277407bac"><ix:nonFraction unitRef="usdPerShare" contextRef="i57518655effb4de5bdcffb7396c85dc7_D20210701-20210731" decimals="2" name="us-gaap:CommonStockDividendsPerShareDeclared" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODkzMA_c0ca5050-8cbc-4439-a1d5-6b56de8c2df2"><ix:nonFraction unitRef="usdPerShare" contextRef="idad3dab92e834ac98e9986b58ed4d7d9_D20201201-20201231" decimals="2" name="us-gaap:CommonStockDividendsPerShareDeclared" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODkzMA_ec0340db-d4f4-42d4-a197-6c7e3c07243b">1.76</ix:nonFraction></ix:nonFraction></ix:nonFraction></ix:nonFraction></ix:nonFraction></ix:nonFraction> per share, which were paid in September 2021, June 2021 and March 2021, respectively. In October 2021, the Board of Directors declared a quarterly cash dividend of $<ix:nonFraction unitRef="usdPerShare" contextRef="i0f1af52b3cdc45b69ad881a053131e62_D20211001-20211031" decimals="2" name="us-gaap:CommonStockDividendsPerShareDeclared" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODk0MA_3f28d309-16bc-4dd6-9999-eb9418073e3d"><ix:nonFraction unitRef="usdPerShare" contextRef="i9b08bc2a35ad4f1b92f1a9c32d536e07_D20211208-20211208" decimals="2" name="us-gaap:CommonStockDividendsPerShareCashPaid" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODk0MA_4c06ed0d-d600-4b48-86c1-739b7062ba8b">1.76</ix:nonFraction></ix:nonFraction> per share, which will be paid on December 8, 2021.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Accumulated other comprehensive income (loss)</span></div><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfOTcz_ae48f3d5-041d-489d-838b-0de09fc329df" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The components of Accumulated other comprehensive income (loss) (AOCI) were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:45.537%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.987%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.987%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.987%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.987%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.995%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Foreign<br/>currency<br/>translation</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Cash&#160;flow<br/>hedges</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Available-for-sale<br/>securities</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">AOCI</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of December 31, 2020</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i770b083713ae40d5abf6f7e80c8202c5_I20201231" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMS0xLTEtMS0w_19728695-df3d-4360-adba-987b03ca1c85">709</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ic6813714a49c4e1ebb1c7f61614d435a_I20201231" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMS0zLTEtMS0w_6fabda9f-7b01-4ee9-a972-9bf411cea1da">263</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8bf4fb9fc5bc4ef5b53a1d2a4b2dbe24_I20201231" decimals="-6" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMS01LTEtMS0w_28b6e27d-6e0a-493a-afb1-638b938594ef">1</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="if822d7ae834a4a6cbea8ec7441e99f34_I20201231" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMS03LTEtMS0w_8d208185-7aa7-4378-8013-442a233cf693">14</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="iaea9ac2193424d918f03fbf56ef30362_I20201231" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMS05LTEtMS0w_6679ed05-28d0-465e-960f-65232a1dccb6">985</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency translation adjustments</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ic640b9e0658f45ddb2d1866ae9c0d679_D20210101-20210331" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMy0xLTEtMS0w_4ac315a0-7d02-4bc4-91e6-4ed5c623d229">39</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i8ff5ee6ed2904950abde3e69e298a888_D20210101-20210331" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMy05LTEtMS0w_c5f01445-21b1-4d70-9235-700c688bac2c">39</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Unrealized gains</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i362a946d783d4675a1537219335e1ecf_D20210101-20210331" decimals="-6" name="us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNC0zLTEtMS0w_16a91f21-2c33-4155-b80e-f1a1652839dd">108</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3490a417c3664ea28df867c0b5b64b99_D20210101-20210331" decimals="-6" format="ixt:fixed-zero" name="us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNC01LTEtMS0w_2f85354f-a145-478c-b488-bc7dc08004d0">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i4f043f0296ab40adbbd000e3a19b8263_D20210101-20210331" decimals="-6" format="ixt:fixed-zero" name="us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNC03LTEtMS0w_80283aaf-a864-4cd6-a422-e0979849dc8a">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8ff5ee6ed2904950abde3e69e298a888_D20210101-20210331" decimals="-6" name="us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNC05LTEtMS0w_e05f5a8c-fdd3-4b62-bbc2-edb3bd08d71b">108</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Reclassification adjustments to income</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i362a946d783d4675a1537219335e1ecf_D20210101-20210331" decimals="-6" name="us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNS0zLTEtMS0w_31196791-1059-46f3-aa9b-edb424071476">133</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3490a417c3664ea28df867c0b5b64b99_D20210101-20210331" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNS01LTEtMS0w_e6f28df0-ad85-4cbc-a20d-ee8bd9c4fe8d">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8ff5ee6ed2904950abde3e69e298a888_D20210101-20210331" decimals="-6" name="us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNS05LTEtMS0w_b9beb08f-0959-40be-9c50-37a925d6a09d">133</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i4f043f0296ab40adbbd000e3a19b8263_D20210101-20210331" decimals="-6" name="amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNi03LTEtMS0w_5095bc67-d829-4c58-82ce-bb0b6920f99b">1</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8ff5ee6ed2904950abde3e69e298a888_D20210101-20210331" decimals="-6" name="amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNi05LTEtMS0w_2b395b9d-4644-412c-b3ae-5bc2b1de2ae2">1</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic640b9e0658f45ddb2d1866ae9c0d679_D20210101-20210331" decimals="-6" format="ixt:fixed-zero" name="us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNy0xLTEtMS0w_8bd428ef-6933-49ae-8873-5298a21f6685">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i362a946d783d4675a1537219335e1ecf_D20210101-20210331" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNy0zLTEtMS0w_af52ca12-6f5f-4ff7-8a07-6bc0e84a3e11">51</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3490a417c3664ea28df867c0b5b64b99_D20210101-20210331" decimals="-6" format="ixt:fixed-zero" name="us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNy01LTEtMS0w_b4ab33ea-8fd8-442f-bf84-e30095328591">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i8ff5ee6ed2904950abde3e69e298a888_D20210101-20210331" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNy05LTEtMS0w_4eb423cc-3634-4ce4-a5a5-1dc9b8087076">51</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of March 31, 2021</span></div></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i3cb26c116a8243b290d914005b2701d7_I20210331" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfOC0xLTEtMS0w_8e93dcff-8f04-42a5-9177-c3a101e31d36">748</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i1bc84cd5a4d7427f8ea0603f5c4fab36_I20210331" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfOC0zLTEtMS0w_57a1f7c0-3983-4f6e-bbc7-63f3a30c186a">73</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i12d709ededf44d88909a52a34d1b6465_I20210331" decimals="-6" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfOC01LTEtMS0w_da733f7e-4069-4ca2-bc96-1aba393acefb">1</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i36d381395cab48a3a0a38dacd23b095d_I20210331" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfOC03LTEtMS0w_7bf3e73b-0d11-45a4-8269-f7de7ccff8a2">13</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i02d7483a082146bca57a490cca649110_I20210331" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfOC05LTEtMS0w_6953129c-abe8-4f8d-8a53-7c2445000d98">833</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency translation adjustments</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i77c6d51206434679bcbf62756fdc2646_D20210401-20210630" decimals="-6" name="us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTAtMS0xLTEtMA_705c97f9-c6b1-4973-a6de-b6a8ae31c667">14</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic34d84ceeae14872821180cf4d7c1fc9_D20210401-20210630" decimals="-6" name="us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTAtOS0xLTEtMA_a74ecd68-6df4-427e-a989-a36bf35d954f">14</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Unrealized losses</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ic28cfd96645b4c7caed54e18d250141a_D20210401-20210630" decimals="-6" sign="-" name="us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTEtMy0xLTEtMA_70c2182a-de23-4211-855a-f13d8afc8fef">31</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i132b85ef12554699b07d3501175ff54f_D20210401-20210630" decimals="-6" format="ixt:fixed-zero" name="us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTEtNS0xLTEtMA_a117cb19-3ffb-4ab4-aeaa-a708e8bf7026">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if0969aa8ef414908986e6dbb1310e704_D20210401-20210630" decimals="-6" format="ixt:fixed-zero" name="us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTEtNy0xLTEtMA_27cd91a7-5b1d-496f-b331-778ad8a65a81">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ic34d84ceeae14872821180cf4d7c1fc9_D20210401-20210630" decimals="-6" sign="-" name="us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTEtOS0xLTEtMA_da3de595-8d7b-41fe-b260-824b930e3dcb">31</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Reclassification adjustments to income</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ic28cfd96645b4c7caed54e18d250141a_D20210401-20210630" decimals="-6" sign="-" name="us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTItMy0xLTEtMA_b889429d-1c9f-4613-bef8-a46a6bed0c2d">28</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i132b85ef12554699b07d3501175ff54f_D20210401-20210630" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTItNS0xLTEtMA_337d0fd1-5de7-4fe3-9c3a-38b26fc79309">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ic34d84ceeae14872821180cf4d7c1fc9_D20210401-20210630" decimals="-6" sign="-" name="us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTItOS0xLTEtMA_7f5b7115-90a6-4086-bb20-f2036b96927e">28</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="if0969aa8ef414908986e6dbb1310e704_D20210401-20210630" decimals="-6" sign="-" name="amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTMtNy0xLTEtMA_567e9d44-1e88-4b70-99d6-a94df2dedccd">1</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ic34d84ceeae14872821180cf4d7c1fc9_D20210401-20210630" decimals="-6" sign="-" name="amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTMtOS0xLTEtMA_86881443-1fa4-4d5d-abfb-532306b806ea">1</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i77c6d51206434679bcbf62756fdc2646_D20210401-20210630" decimals="-6" format="ixt:fixed-zero" name="us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTQtMS0xLTEtMA_fe68093a-dc4f-4836-baad-25bf6d86cba0">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic28cfd96645b4c7caed54e18d250141a_D20210401-20210630" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTQtMy0xLTEtMA_0e8544f6-1772-4d9a-aaa8-34d4d6f6efc4">11</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i132b85ef12554699b07d3501175ff54f_D20210401-20210630" decimals="-6" format="ixt:fixed-zero" name="us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTQtNS0xLTEtMA_620bfd21-4a3f-4582-a4f2-d36dc0d6c96f">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic34d84ceeae14872821180cf4d7c1fc9_D20210401-20210630" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTQtOS0xLTEtMA_a6f150d7-5ddf-4812-b641-199476b345fb">11</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of June 30, 2021</span></div></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ia5b73fcb215b4f1fb5f74cc40aac6a12_I20210630" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTUtMS0xLTEtMA_fd09c747-6540-4ee1-a1c2-b5d26432ba67">734</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="if425fe5fd2294df9a8d0f639c5037ec9_I20210630" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTUtMy0xLTEtMA_ba552bb9-5d31-4cda-8374-977cc01d42f7">121</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id85f7578a3bc49ca89f363dce5fb32aa_I20210630" decimals="-6" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTUtNS0xLTEtMA_0d02c68b-298a-4619-be07-28ba9cc00bfa">1</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i0fdb28b3619543a79bc3b17b1cc0a2d4_I20210630" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTUtNy0xLTEtMA_737e9bf2-1777-4115-87f3-dbd2541e95d1">14</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i9d079f6d807e45a8b0ea7b4bf5ca1b1c_I20210630" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTUtOS0xLTEtMA_1668280b-8fa5-43c3-a6f0-15198ba9371f">868</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency translation adjustments</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ief03f026e49a44918a54a590451e6db3_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTYtMS0xLTEtMA_56cc4cc9-86ed-4787-a037-bbe6b02c0a8d">35</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i984e708e2ca94952a077181e38e25d78_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTYtOS0xLTEtMA_5b254c93-c40a-4efd-83ef-f22cfd3c6107">35</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Unrealized gains (losses)</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i98ef59b24516466ebfc3d73a98308ecf_D20210701-20210930" decimals="-6" name="us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTctMy0xLTEtMA_183495b8-6722-45dd-8620-b4a70ad46eff">16</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i719883141b814809a34bc70ed81e53a0_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTctNS0xLTEtMA_28869821-cda1-474d-bddf-e00857b99478">1</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i45a15717cb5141c5864e39d52a2a95fc_D20210701-20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTctNy0xLTEtMA_65b6a705-4732-4dd7-b3c8-b44262ffbcdf">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i984e708e2ca94952a077181e38e25d78_D20210701-20210930" decimals="-6" name="us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTctOS0xLTEtMA_66649184-6b61-4934-91bf-e409801ce7db">15</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Reclassification adjustments to income</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i98ef59b24516466ebfc3d73a98308ecf_D20210701-20210930" decimals="-6" name="us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTgtMy0xLTEtMA_77c9b7e4-334a-4f4a-8de5-6ca68929cf47">109</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i719883141b814809a34bc70ed81e53a0_D20210701-20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTgtNS0xLTEtMA_9d2eb7e6-2ba6-4e79-9f23-307b02b9aad3">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i984e708e2ca94952a077181e38e25d78_D20210701-20210930" decimals="-6" name="us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTgtOS0xLTEtMA_b74da7ab-19a8-41d5-b3cc-a83e6fb34dd4">109</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i45a15717cb5141c5864e39d52a2a95fc_D20210701-20210930" decimals="-6" sign="-" name="amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTktNy0xLTEtMA_0379cee9-1cd8-48db-bb7f-c1dc6b1474fe">3</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i984e708e2ca94952a077181e38e25d78_D20210701-20210930" decimals="-6" sign="-" name="amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTktOS0xLTEtMA_8e2d8a11-2b82-4c54-86c7-e92d16c8ade5">3</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ief03f026e49a44918a54a590451e6db3_D20210701-20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjAtMS0xLTEtMA_1da97942-c963-40d9-aca3-effbfd9a5c9d">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i98ef59b24516466ebfc3d73a98308ecf_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjAtMy0xLTEtMA_43797279-e738-4020-82a8-9da6a3fc9e58">26</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i719883141b814809a34bc70ed81e53a0_D20210701-20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjAtNS0xLTEtMA_80162588-5817-44f7-b29f-4ca531ee1cf9">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i984e708e2ca94952a077181e38e25d78_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjAtOS0xLTEtMA_24281e17-30bd-4fe6-a595-0afa5ff12d06">26</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of September 30, 2021</span></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ieede5746b0d64fdbbf75791dacc0ef9d_I20210930" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjEtMS0xLTEtMA_f2a7cf4a-5f3d-437a-984d-0e7fce6a3ddd">769</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i672a17c30f404de680e008be9b6464aa_I20210930" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjEtMy0xLTEtMA_e41f20d7-170f-44d8-9287-8a442cd65574">22</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9660b813f8e644d8b66ad3118538f278_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjEtNS0xLTEtMA_198bdc04-ff4b-4ae1-b009-df09775c6a58">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i24a9272b1ce44928aa5b6ba2a3c47e9f_I20210930" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjEtNy0xLTEtMA_4fe3a041-090e-463a-add6-5f9fffa9d907">17</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ic860f31327384ad08f5dbf6d59cdb763_I20210930" decimals="-6" sign="-" name="us-gaap:StockholdersEquity" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjEtOS0xLTEtMA_7d42a4c3-0483-4b07-8aab-9fc223549db2">808</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div></ix:nonNumeric></ix:continuation><div style="margin-bottom:8pt;margin-top:7pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">18</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><ix:continuation id="ie3fda48d8ee546a5918b4be787391818"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfOTM1_e197ed1b-4cb7-4dfc-b764-a546c97c0ced" escape="true"><div style="margin-bottom:8pt;margin-top:7pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Reclassifications out of AOCI and into earnings, including related income tax expenses, were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:39.104%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:14.543%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:14.543%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:25.220%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Components of AOCI</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Statements of Income locations</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash flow hedges:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contract (losses) gains</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i32d3947cf2c945deb867f411799b6962_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMy0yLTEtMS0w_f1229e8d-1280-4be6-9c17-08794318f31a">5</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i671c24fb8d22406aa2608b0eaf66e7ea_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMy00LTEtMS0w_8b0203f0-cf93-439c-aba7-d2026d025905">41</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Product sales</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contract (losses) gains</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i605067db02764f2ca67c7def81eb8b61_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfNC0yLTEtMS0w_fe49ce8b-4916-4b8e-b5ef-e343aa56f617">104</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i956f0c0215934258b02d8cc62b9f996d_D20200701-20200930" decimals="-6" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfNC00LTEtMS0w_16794c32-9b60-4702-80ea-fdfe35cf305f">183</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income, net</span></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i774914ff61704f25a808fe591907f07a_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfNi0yLTEtMS0w_09e7e58d-8fa0-4c55-94f2-00cc8bea979c">109</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3bd653c39f1d495b9c484952593554a1_D20200701-20200930" decimals="-6" name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfNi00LTEtMS0w_38562b15-64c0-4c5d-91df-e86aef615b26">224</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income before income taxes</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i774914ff61704f25a808fe591907f07a_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:IncomeTaxExpenseBenefit" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfNy0yLTEtMS0w_5e75099e-cba6-435d-8f83-5a906f80bf0b">23</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i3bd653c39f1d495b9c484952593554a1_D20200701-20200930" decimals="-6" name="us-gaap:IncomeTaxExpenseBenefit" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfNy00LTEtMS0w_64e0f217-b29e-4f48-b09c-9e0b9480e45b">49</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Provision for income taxes</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i774914ff61704f25a808fe591907f07a_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfOC0yLTEtMS0w_fea58ec8-5720-4229-9439-0934cafe538e">86</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3bd653c39f1d495b9c484952593554a1_D20200701-20200930" decimals="-6" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfOC00LTEtMS0w_0dc4f723-1827-43a9-bcea-7cf6eb802686">175</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Available-for-sale securities:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net realized gains</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i66702e11ddcd4d94b4f6a53b4231f09f_D20210701-20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTAtMi0xLTEtMA_45f9b649-f66c-46a7-8ea3-6f11d2e1576d">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ice9f1dfc8f83445b9b89ebcebe763f1a_D20200701-20200930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTAtNC0xLTEtMA_c7d30930-33a7-4f9c-bf4b-9d0d51c53d44">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i66702e11ddcd4d94b4f6a53b4231f09f_D20210701-20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:IncomeTaxExpenseBenefit" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTEtMi0xLTEtMA_a8f49328-f491-49af-b3db-084a0b8e824a">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ice9f1dfc8f83445b9b89ebcebe763f1a_D20200701-20200930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:IncomeTaxExpenseBenefit" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTEtNC0xLTEtMA_9d3dac9e-c7ec-4c20-8b57-38e51bdce998">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Provision for income taxes</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i66702e11ddcd4d94b4f6a53b4231f09f_D20210701-20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTItMi0xLTEtMA_3e787878-a8cf-459b-878a-96a326fcb54d">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ice9f1dfc8f83445b9b89ebcebe763f1a_D20200701-20200930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTItNC0xLTEtMA_8d0e7ecb-a071-4753-aaf5-57143645e9e9">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="9" style="background-color:#ffffff;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended September 30,</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Components of AOCI</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Statements of Income locations</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash flow hedges:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contract (losses) gains</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ibd9038c5b623433f87f5b5ece6980092_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTctMi0xLTEtMA_5ad4d4a3-3747-4490-be26-d17200dc78ba">24</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74e3224ed0df4d7b844d1e04f9657708_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTctNC0xLTEtMA_1ce87d44-af95-4540-9a00-5a46dedb0c05">158</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Product sales</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contract (losses) gains</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="iba01b07f6b98472d83708a5396a4df3b_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTgtMi0xLTEtMA_bf66088e-1d3b-4957-a570-a5289de4404c">190</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i67a805bd27be4c1fb6e4f9f773fd62d8_D20200101-20200930" decimals="-6" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTgtNC0xLTEtMA_c89c7466-0bac-4eee-b819-d49151b8b0db">101</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income, net</span></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i7702c711db32401d9e72b707815b70d5_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjAtMi0xLTEtMA_3c330f32-1c31-46fd-91d1-f58f085ffbb4">214</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if763cdb48cee4124a55a518d0549ffcd_D20200101-20200930" decimals="-6" name="us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjAtNC0xLTEtMA_d57b4714-bd76-4698-9d86-80f2d04106e5">259</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income before income taxes</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7702c711db32401d9e72b707815b70d5_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:IncomeTaxExpenseBenefit" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjEtMi0xLTEtMA_b873212d-06af-4c07-b8de-cc1f81014f5b">45</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="if763cdb48cee4124a55a518d0549ffcd_D20200101-20200930" decimals="-6" name="us-gaap:IncomeTaxExpenseBenefit" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjEtNC0xLTEtMA_ba22bdfa-bd85-4572-b913-49e0a91fae9e">57</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Provision for income taxes</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i7702c711db32401d9e72b707815b70d5_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjItMi0xLTEtMA_7963e816-9d33-4bf2-8372-bfd9d2f0eb59">169</ix:nonFraction>)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if763cdb48cee4124a55a518d0549ffcd_D20200101-20200930" decimals="-6" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjItNC0xLTEtMA_675fecd3-ba51-4f7b-80a8-6aa4e419c1b4">202</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Available-for-sale securities:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net realized gains</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ifd7b5626cee240a48eb61b6441030918_D20210101-20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjQtMi0xLTEtMA_6459277a-8a0d-4e6b-8dc6-5b989f817b46">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iee30caa26817491b92bd2d46a5a5214d_D20200101-20200930" decimals="-6" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjQtNC0xLTEtMA_1b1b700e-f1bf-418d-b83a-ed22898ab3dd">33</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ifd7b5626cee240a48eb61b6441030918_D20210101-20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:IncomeTaxExpenseBenefit" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjUtMi0xLTEtMA_c1d26343-d47f-4404-b421-5bf70f589564">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="iee30caa26817491b92bd2d46a5a5214d_D20200101-20200930" decimals="-6" name="us-gaap:IncomeTaxExpenseBenefit" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjUtNC0xLTEtMA_2d5588a7-4dbc-46ec-b526-c50854fe09a1">7</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Provision for income taxes</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ifd7b5626cee240a48eb61b6441030918_D20210101-20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjYtMi0xLTEtMA_d753e9d1-37ec-4fb5-b9ad-0989391c7830">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iee30caa26817491b92bd2d46a5a5214d_D20200101-20200930" decimals="-6" name="us-gaap:NetIncomeLoss" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjYtNC0xLTEtMA_1c44861a-2f50-4a04-8cd6-38cb9ee73296">26</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td></tr></table></div></ix:nonNumeric></ix:continuation><div style="text-align:justify"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_64"></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">12. <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:FairValueDisclosuresTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RleHRyZWdpb246MDBlOGE3MGFkYTlmNDA5Yzk4NTQ5YWNkM2NlMjA2NjBfNDM3NQ_1d2d0889-0ae0-44ad-9e5f-50b70e7d32f6" continuedAt="i33a9de8122c54dd88258c4d3b0b682aa" escape="true">Fair value measurement</ix:nonNumeric></span></div><ix:continuation id="i33a9de8122c54dd88258c4d3b0b682aa" continuedAt="i5814c5b702a34f1f8912d97ae0e1c3a6"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">To estimate the fair value of our financial assets and liabilities, we use valuation approaches within a hierarchy that maximizes the use of observable inputs and minimizes the use of unobservable inputs by requiring that observable inputs be used when available. Observable inputs are inputs that market participants would use in pricing an asset or liability based on market data obtained from sources independent of the Company. Unobservable inputs are inputs that reflect the Company&#8217;s assumptions about the inputs that market participants would use in pricing an asset or liability and are developed based on the best information available in the circumstances. The fair value hierarchy is divided into three levels based on the source of inputs as follows:</span></div><div style="margin-bottom:1pt;text-align:center;text-indent:22.5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:98.391%"><tr><td style="width:1.0%"></td><td style="width:6.180%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:2.177%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:89.243%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Level&#160;1</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;</span></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Valuations based on unadjusted quoted prices in active markets for identical assets or liabilities that the Company has the ability to access</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Level&#160;2</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;</span></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Valuations for which all significant inputs are observable either directly or indirectly&#8212;other than Level 1 inputs</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Level&#160;3</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;</span></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Valuations based on inputs that are unobservable and significant to the overall fair value measurement</span></td></tr></table></div></ix:continuation><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">19</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><ix:continuation id="i5814c5b702a34f1f8912d97ae0e1c3a6" continuedAt="icf41614ee86e444c8e9cb6147d24cd29"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The availability of observable inputs can vary among different types of financial assets and liabilities. To the extent that the valuation is based on models or inputs that are less observable or unobservable in the market, the determination of fair value requires more judgment. In certain cases, the inputs used for measuring fair value may fall into different levels of the fair value hierarchy. In such cases, for financial statement disclosure purposes, the level in the fair value hierarchy within which the fair value measurement is categorized is based on the lowest level of input used that is significant to the overall fair value measurement.</span></div><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RleHRyZWdpb246MDBlOGE3MGFkYTlmNDA5Yzk4NTQ5YWNkM2NlMjA2NjBfNDM2Mw_f3df4040-9ca7-4404-b067-058aa25dfcbd" continuedAt="i1f8e51372bb9492da15cd9ded11ed5eb" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of each major class of the Company&#8217;s financial assets and liabilities measured at fair value on a recurring basis were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:40.420%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.788%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.788%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.788%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.796%"></td><td style="width:0.1%"></td></tr><tr style="height:12pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Quoted&#160;prices in<br/>active&#160;markets&#160;for<br/>identical assets<br/>(Level 1)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Significant<br/>other&#160;observable<br/>inputs<br/>(Level 2)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Significant<br/>unobservable<br/>inputs<br/>(Level 3)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr style="height:12pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr style="height:12pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair value measurement as of September 30, 2021, using:</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Assets:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Available-for-sale securities:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i826a29ed0f7a402ea34f70df227b7521_I20210930" decimals="-6" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNS0yLTEtMS0w_0ae4db44-b77a-42ec-98b5-f76f1b841f49">51</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7d76b8e7f94f45cc9e548d9fb2040f2d_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNS00LTEtMS0w_bf3a5ed4-e6e1-4162-ade8-6611d3e23f98">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i37882f19b0784eccafabfe836dc51f25_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNS02LTEtMS0w_03614a8d-9dee-49a6-a326-0cfd8462863c">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i0523566bb4bd4ac7a167861d41b07412_I20210930" decimals="-6" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNS04LTEtMS0w_a31516d1-deed-41cf-aebb-84ef61cfa48f">51</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury bills</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if0fb1e0d683243249078c344db9e3287_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNi0yLTEtMS0w_53a06fb1-5476-4225-9a13-15844c71dcd9">3,900</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie0b4aff0ec6c41e18c08f8a27f8d35d6_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNi00LTEtMS0w_19607e61-e7e7-446a-8679-7b8206023633">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9bf07042070142818b2dcc65da76d130_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNi02LTEtMS0w_5d59ecd2-b02a-4afb-9449-f841d1a83d26">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8db023e72bf0457098764c83dfe06255_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNi04LTEtMS0w_716218a1-eb14-4f13-b597-966e66925061">3,900</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Money market mutual funds</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1b770f2bad0a458bb80d6080d416e653_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTYtMi0xLTEtMA_7cd2d0ba-250a-48dc-a354-682cbf826b16">8,323</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1b4470fbc2904831b9b368445e211ea4_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTYtNC0xLTEtMA_492e5018-73c3-4709-8d5e-995411acce56">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i33c195572dca4fbf824c6e47b083ab07_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTYtNi0xLTEtMA_147fdef7-cc0b-4880-8cfa-c209de6bcb9f">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3022e170e868460588b8873ad8b918de_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTYtOC0xLTEtMA_978b58d1-e6e8-43e7-91c0-f32de270bc2c">8,323</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other short-term interest-bearing securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i63f7d63505ec40e78832bd42bf718996_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTctMi0xLTEtMA_0cd1fde1-ea20-4700-9586-d54574da180c">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i25e32e59bf21440087114ea6114b506b_I20210930" decimals="-6" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTctNC0xLTEtMA_e5f3a0b5-2278-4961-afcd-5640bda57b33">1</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iab7f53e834574888ab2bc9ca340df3f0_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTctNi0xLTEtMA_6827b8cc-f2db-4f58-9904-47b14ac68511">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic7d3b5bd8e574e95949520f4cff15af1_I20210930" decimals="-6" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTctOC0xLTEtMA_a46a27b3-b6a8-4139-a050-df58bcf932d2">1</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Equity securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ib2b89ed4eb094c5f966961837399b7ca_I20210930" decimals="-6" name="us-gaap:EquitySecuritiesFvNi" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTgtMi0xLTEtMA_609b626b-c65c-460c-953a-0143d7fd76af">608</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i668050cd480a44d59980ffd4209aa796_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:EquitySecuritiesFvNi" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTgtNC0xLTEtMA_babedd22-518f-4564-a91e-a6fd993be8da">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9d7900fb43d041f4bbfa2d693a513c61_I20210930" decimals="-6" name="us-gaap:EquitySecuritiesFvNi" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTgtNi0xLTEtMA_ec087135-e34f-49ff-944a-a11e81ed59ea">257</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" name="us-gaap:EquitySecuritiesFvNi" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTgtOC0xLTEtMA_6ab0345a-95e2-4d39-8fca-69d7769a6148">865</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i222681c138f44598b25427e0b8ccae76_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjAtMi0xLTEtMA_228a3774-299e-42f9-b89a-f07b4287cde5">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="idb72f426587a4ec5befa804534b12722_I20210930" decimals="-6" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjAtNC0xLTEtMA_0f833fe8-a1f9-4fed-b397-4725fe1ef710">127</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i25541eb9d6c34199be9b71a30ee0401d_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjAtNi0xLTEtMA_deba8c70-113a-4a75-9196-89103644dc65">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9e90f12e90a449639d72687889f2e95a_I20210930" decimals="-6" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjAtOC0xLTEtMA_bc124ce4-7949-4bfc-9287-88ff06dc8a8b">127</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ied5df9df96c04c2ba41897fd892ef61f_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjEtMi0xLTEtMA_9016dcec-bed8-44a5-a6ff-425138db7cf5">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id8e22719623e4f98b17f615c76dbb3bd_I20210930" decimals="-6" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjEtNC0xLTEtMA_190a600f-66aa-4684-9b8c-763d1853df98">119</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="icef3bcd64f2c4ba38b4e195178b28e0a_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjEtNi0xLTEtMA_04d3f672-8d0f-4a92-996f-df3f950a52de">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i06db08463971480086be884f8fb2f0d5_I20210930" decimals="-6" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjEtOC0xLTEtMA_6282b28d-a667-40b3-af03-ce6a8b687ee2">119</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i891c6c71b8e7435ea6af4ad541a9f170_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:InterestRateFairValueHedgeAssetAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjItMi0xLTEtMA_89b2ac78-8987-4cab-aa18-5b6a819b54ff">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i905b99ada59844fe9615f05632d936ba_I20210930" decimals="-6" name="us-gaap:InterestRateFairValueHedgeAssetAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjItNC0xLTEtMA_e8ac2fb7-1e9f-4b4a-81af-a7058e029037">29</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id43e4d99182d4a8fa11017c14d8cff33_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:InterestRateFairValueHedgeAssetAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjItNi0xLTEtMA_1f425a62-c0bc-416c-a2ee-82cf0c13bfad">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i0345015d43454b10b538d7fe7b901fa5_I20210930" decimals="-6" name="us-gaap:InterestRateFairValueHedgeAssetAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjItOC0xLTEtMA_b7605d40-4c86-4a68-9d96-c3cc20245acc">29</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ib2b89ed4eb094c5f966961837399b7ca_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AssetsFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjQtMi0xLTEtMA_1bcf9c35-e996-4bc6-b194-d577b731d7d4">12,882</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i668050cd480a44d59980ffd4209aa796_I20210930" decimals="-6" name="us-gaap:AssetsFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjQtNC0xLTEtMA_4fac71a4-16e6-4ae1-8e37-094b83358be6">276</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9d7900fb43d041f4bbfa2d693a513c61_I20210930" decimals="-6" name="us-gaap:AssetsFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjQtNi0xLTEtMA_7dabe0a6-64c7-4e7b-8d77-9bdd39a924db">257</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AssetsFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjQtOC0xLTEtMA_301d042a-2d34-4886-b27c-709a6dd8dfdd">13,415</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Liabilities:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i222681c138f44598b25427e0b8ccae76_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjgtMi0xLTEtMA_650e4952-ed14-4db5-9bb2-f3d5616b39bc">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="idb72f426587a4ec5befa804534b12722_I20210930" decimals="-6" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjgtNC0xLTEtMA_504ee7a0-bed6-4f33-8615-c1c5f62b6a7b">54</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i25541eb9d6c34199be9b71a30ee0401d_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjgtNi0xLTEtMA_fa34038a-5b57-43ca-91aa-7376a85731ea">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9e90f12e90a449639d72687889f2e95a_I20210930" decimals="-6" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjgtOC0xLTEtMA_06250bf9-8f7c-4369-9084-f83071b00718">54</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ied5df9df96c04c2ba41897fd892ef61f_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjktMi0xLTEtMA_2bb59231-a5c9-4aed-8f96-5feaf6d557c8">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id8e22719623e4f98b17f615c76dbb3bd_I20210930" decimals="-6" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjktNC0xLTEtMA_dab2ed6a-7543-4874-86f6-f7d752c78498">360</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="icef3bcd64f2c4ba38b4e195178b28e0a_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjktNi0xLTEtMA_ef1ad914-1994-4cf7-a58f-8d83c0d359e6">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i06db08463971480086be884f8fb2f0d5_I20210930" decimals="-6" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjktOC0xLTEtMA_e2c4bd84-1ac1-4a43-b1a9-7f3d37093cf1">360</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i891c6c71b8e7435ea6af4ad541a9f170_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzAtMi0xLTEtMA_763cb849-3dbd-4099-86b9-6bea38e8907f">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i905b99ada59844fe9615f05632d936ba_I20210930" decimals="-6" name="us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzAtNC0xLTEtMA_f648e1b8-e45e-4bae-925f-2c67b1f84cf8">105</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id43e4d99182d4a8fa11017c14d8cff33_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzAtNi0xLTEtMA_344e3e32-a4b2-4d13-9f69-06c880b35fe4">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i0345015d43454b10b538d7fe7b901fa5_I20210930" decimals="-6" name="us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzAtOC0xLTEtMA_3926d83b-fa0c-4fac-b0cf-c6f5898dec09">105</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Contingent consideration obligations</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ib2b89ed4eb094c5f966961837399b7ca_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:BusinessCombinationContingentConsiderationLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzEtMi0xLTEtMA_4b0392d9-956a-42a4-bfce-a5bb13f4e695">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i668050cd480a44d59980ffd4209aa796_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:BusinessCombinationContingentConsiderationLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzEtNC0xLTEtMA_346ba1db-95b5-4c3b-8e28-8f4da7ae4183">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9d7900fb43d041f4bbfa2d693a513c61_I20210930" decimals="-6" name="us-gaap:BusinessCombinationContingentConsiderationLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzEtNi0xLTEtMA_8c2b4425-18da-4b95-a225-18c142c269df">35</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" name="us-gaap:BusinessCombinationContingentConsiderationLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzEtOC0xLTEtMA_cecc1e26-dc8a-450a-963c-209b9e58c97c">35</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total liabilities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ib2b89ed4eb094c5f966961837399b7ca_I20210930" decimals="-6" format="ixt:fixed-zero" name="us-gaap:LiabilitiesFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzItMi0xLTEtMA_9a60ce38-b702-4595-9b4b-ba0e3bbe7347">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i668050cd480a44d59980ffd4209aa796_I20210930" decimals="-6" name="us-gaap:LiabilitiesFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzItNC0xLTEtMA_016c4ceb-8e3a-4d69-877b-42a424e68587">519</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9d7900fb43d041f4bbfa2d693a513c61_I20210930" decimals="-6" name="us-gaap:LiabilitiesFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzItNi0xLTEtMA_6a092a82-f49b-4160-8396-9dcb205ad941">35</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-6" name="us-gaap:LiabilitiesFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzItOC0xLTEtMA_0d6c183a-e0aa-4966-9a63-626b9443da55">554</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div></ix:nonNumeric></ix:continuation><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">20</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><ix:continuation id="icf41614ee86e444c8e9cb6147d24cd29" continuedAt="iaee1e247e63640658b833843941f19cc"><div style="margin-bottom:8pt"><ix:continuation id="i1f8e51372bb9492da15cd9ded11ed5eb"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:40.420%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.788%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.788%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.788%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:12.796%"></td><td style="width:0.1%"></td></tr><tr style="height:11pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Quoted&#160;prices in<br/>active&#160;markets&#160;for<br/>identical assets<br/>(Level 1)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Significant<br/>other observable<br/>inputs<br/>(Level 2)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Significant<br/>unobservable<br/>inputs<br/>(Level 3)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr style="height:12pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr style="height:15pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair value measurement as of December 31, 2020, using:</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Assets:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Available-for-sale securities:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7d9048c66277472987f2e5c853ea849f_I20201231" decimals="-6" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNS0yLTEtMS0w_639f1da8-174e-4967-b188-6d2a0fd06280">130</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if46f80f8f61a471bbd2f2cd5ffc18024_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNS00LTEtMS0w_1be347dd-cdfd-4f2d-b080-a79a27d56814">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ifb485de2ab374debabfd24e341e4d676_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNS02LTEtMS0w_034d9586-40e6-4e47-a070-7179b59295cc">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i507488fbf87d4c6296eb13e3e0006fbf_I20201231" decimals="-6" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNS04LTEtMS0w_2d4bb2c0-c68c-4cee-881b-f7389b2705a9">130</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury bills</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ibbe73c36ec8a41f991d38edd0c64bb47_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNi0yLTEtMS0w_677ba725-5cdd-44f1-907a-22eba04972a7">4,948</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ib8fabc2c97464ca0bbc9f7eb0a1fce39_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNi00LTEtMS0w_079dc274-b2de-4ee0-87bc-023337926526">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9c8094c8dc344979833ee0c0a4184c0f_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNi02LTEtMS0w_c6a6dd02-d242-4c53-ae67-850824359a3b">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i8ba30f0c09fc4bfd9fe36a47079d2854_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNi04LTEtMS0w_88c85d93-1165-4043-af22-c86ec2abba73">4,948</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Money market mutual funds</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic99616af30c6481c95e52063cc58aab7_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTYtMi0xLTEtMA_759fac78-42f8-442d-82c7-bf69792effd5">4,765</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id4322deb32b242dc9dc95226e1f24e7a_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTYtNC0xLTEtMA_342cb528-03ad-492f-a378-d55784864ee8">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5720d28c85fd42cf9bf79344cb93f92e_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTYtNi0xLTEtMA_9378da22-c753-4cc7-86b0-b3edd514fff9">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i54f838959ac943e79d09dcf9e6faada4_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTYtOC0xLTEtMA_75f58e4f-9887-4156-b27c-973d35211fc3">4,765</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other short-term interest-bearing securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dc6f4e8be7843d6aaca2adf5f4c6884_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTctMi0xLTEtMA_c896e08a-7b0b-46c6-b2be-64a1d15b0324">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id158e2e208fe42f6babb0bf2b8d9c0fd_I20201231" decimals="-6" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTctNC0xLTEtMA_80b5f858-6df2-43d4-9c72-52e43dfcf8b7">2</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i0d6271a8a04b419399a0b38f81c5198f_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTctNi0xLTEtMA_d7978717-9463-4900-ae8b-d4a09a168d1c">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i84edbdc908bc4493a769cf963ac32f28_I20201231" decimals="-6" name="us-gaap:AvailableForSaleSecuritiesDebtSecurities" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTctOC0xLTEtMA_2eb928e9-e2a3-4fba-bd6c-9cf44e44f851">2</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Equity securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia0271b62203b4afbbefbea6461a32a14_I20201231" decimals="-6" name="us-gaap:EquitySecuritiesFvNi" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTgtMi0xLTEtMA_6c1450cb-3551-410d-809a-0032386720d5">477</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie0f44542e8c740659e299accf3ca4908_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:EquitySecuritiesFvNi" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTgtNC0xLTEtMA_84c83ddc-7e61-43b0-8e1d-faedb1705c4d">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie342e06932cb4eb09ce0c2794ac21c83_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:EquitySecuritiesFvNi" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTgtNi0xLTEtMA_c1024950-6d85-479e-b929-8ca521110b06">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" name="us-gaap:EquitySecuritiesFvNi" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTgtOC0xLTEtMA_8d4b85cd-0ad3-443d-aa6d-d782e2e6c4f1">477</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i54877d697b024c418e4690308061e7d5_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjAtMi0xLTEtMA_90d0a641-c7bf-4577-844f-21cd20b6c63f">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i454c26ac3d9f4433aebd4f00ce56ef66_I20201231" decimals="-6" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjAtNC0xLTEtMA_8d9d4fe9-dff5-4e46-84d5-6016a7b586f9">28</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i367c35eaeba64e7dacfc5f757575d411_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjAtNi0xLTEtMA_142c08cd-efb4-4bfa-98b4-c7609f27904a">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5d128d2186654d918c38f7fc1d9b358c_I20201231" decimals="-6" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjAtOC0xLTEtMA_b0256ec6-1c82-4b7c-83a9-9673a7fcbf9b">28</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i17fe29849f934c778d329dd2ac540b0f_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjEtMi0xLTEtMA_4f80c360-dffa-486b-99eb-95e1a56317cb">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1f484e76b00143c49d1ffb0c04e1aa31_I20201231" decimals="-6" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjEtNC0xLTEtMA_72c8a9f4-9705-40aa-9378-d860bdab0a73">255</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i62f678821295404c8ddc6c8b0b67d7e2_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjEtNi0xLTEtMA_2e4389e0-ee76-4caa-addc-ea9706776ca6">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2cc8acfb8b1c4f2eaf54f3edfd2fca61_I20201231" decimals="-6" name="us-gaap:ForeignCurrencyContractAssetFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjEtOC0xLTEtMA_7d2aef1a-2078-4d3b-94ff-f7b2c513f440">255</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i84e77eb97532442da0b8735429da4ecc_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:InterestRateFairValueHedgeAssetAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjItMi0xLTEtMA_b43d91c0-43cc-4465-a0b7-d69540f77cec">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ifc9c4b5754af40009253488e23ef0207_I20201231" decimals="-6" name="us-gaap:InterestRateFairValueHedgeAssetAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjItNC0xLTEtMA_0021afd7-192c-4bc8-99b6-1bf0d1f83a35">66</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i69ee586072574a02b0f1bc1f4029919c_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:InterestRateFairValueHedgeAssetAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjItNi0xLTEtMA_0a10c265-52c9-43f1-94dc-fd14f490bdbe">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1197e68d9d604430b8ce3c78e941f5f2_I20201231" decimals="-6" name="us-gaap:InterestRateFairValueHedgeAssetAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjItOC0xLTEtMA_43abfe45-d15a-4c6f-9333-d5e7698ddfdd">66</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia0271b62203b4afbbefbea6461a32a14_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AssetsFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjMtMi0xLTEtMA_59c95555-310a-4ccb-9d24-efce0a659d90">10,320</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie0f44542e8c740659e299accf3ca4908_I20201231" decimals="-6" name="us-gaap:AssetsFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjMtNC0xLTEtMA_608d17ea-94e6-4f64-8eba-13f6910ca9b1">351</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie342e06932cb4eb09ce0c2794ac21c83_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:AssetsFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjMtNi0xLTEtMA_84e551e2-afa7-4184-a7aa-989d3494451b">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:AssetsFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjMtOC0xLTEtMA_64a18593-2ae1-45d1-ba22-760da12c9a51">10,671</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Liabilities:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i54877d697b024c418e4690308061e7d5_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjctMi0xLTEtMA_6c0da948-7445-4e7d-9ec9-0482a2c9f3fa">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i454c26ac3d9f4433aebd4f00ce56ef66_I20201231" decimals="-6" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjctNC0xLTEtMA_ad416f9f-81cc-485d-b74b-f89ef2f360b5">237</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i367c35eaeba64e7dacfc5f757575d411_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjctNi0xLTEtMA_11c6488f-08f7-47c6-b457-f7acab80e55e">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5d128d2186654d918c38f7fc1d9b358c_I20201231" decimals="-6" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjctOC0xLTEtMA_4efa764c-fc5d-46fc-b90c-80e6bf3a0ad9">237</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i17fe29849f934c778d329dd2ac540b0f_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjgtMi0xLTEtMA_13fc96ca-eb84-4226-b78b-60c8c69463cd">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1f484e76b00143c49d1ffb0c04e1aa31_I20201231" decimals="-6" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjgtNC0xLTEtMA_5804231a-2449-4534-bc3b-ea433066852d">318</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i62f678821295404c8ddc6c8b0b67d7e2_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjgtNi0xLTEtMA_f3da9320-c120-4222-81c8-e9d69d3c65fb">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2cc8acfb8b1c4f2eaf54f3edfd2fca61_I20201231" decimals="-6" name="us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjgtOC0xLTEtMA_2a7387b6-5e56-4efb-879d-247615dad3d3">318</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i84e77eb97532442da0b8735429da4ecc_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjktMi0xLTEtMA_84b8c600-dd63-4b89-a795-37e7d456fb0f">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ifc9c4b5754af40009253488e23ef0207_I20201231" decimals="-6" name="us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjktNC0xLTEtMA_dc9cfc59-ab6e-42af-b6af-9468b1aa4346">15</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i69ee586072574a02b0f1bc1f4029919c_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjktNi0xLTEtMA_18cae5d5-eb1a-4933-a6d5-895e64fbe594">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1197e68d9d604430b8ce3c78e941f5f2_I20201231" decimals="-6" name="us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjktOC0xLTEtMA_11355877-863a-4205-ab07-1724868a3908">15</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Contingent consideration obligations</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia0271b62203b4afbbefbea6461a32a14_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:BusinessCombinationContingentConsiderationLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzAtMi0xLTEtMA_7a736c1f-94b9-43cd-8a7e-4bc8a51fed6d">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie0f44542e8c740659e299accf3ca4908_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:BusinessCombinationContingentConsiderationLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzAtNC0xLTEtMA_6afb56e3-5179-46a7-96c0-bd58363dedd4">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie342e06932cb4eb09ce0c2794ac21c83_I20201231" decimals="-6" name="us-gaap:BusinessCombinationContingentConsiderationLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzAtNi0xLTEtMA_53fc1f53-491e-4dc8-9691-34e87bd1047e">33</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" name="us-gaap:BusinessCombinationContingentConsiderationLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzAtOC0xLTEtMA_238d6171-1b6b-4fb6-9777-6b5d2e072a40">33</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total liabilities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia0271b62203b4afbbefbea6461a32a14_I20201231" decimals="-6" format="ixt:fixed-zero" name="us-gaap:LiabilitiesFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzEtMi0xLTEtMA_50a7a671-1604-41b2-8de0-accd5ce4337f">&#8212;</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie0f44542e8c740659e299accf3ca4908_I20201231" decimals="-6" name="us-gaap:LiabilitiesFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzEtNC0xLTEtMA_bbe66dad-488e-42cd-9ef8-304c1f64a606">570</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie342e06932cb4eb09ce0c2794ac21c83_I20201231" decimals="-6" name="us-gaap:LiabilitiesFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzEtNi0xLTEtMA_0e117619-c89e-459e-8729-90e6bbebc64f">33</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-6" name="us-gaap:LiabilitiesFairValueDisclosure" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzEtOC0xLTEtMA_e54eee54-421a-4574-a88a-5ad398fa3985">603</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></ix:continuation></div><div style="text-align:justify"><span><br/></span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Interest-bearing and equity securities</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of our U.S. Treasury securities, money market mutual funds and equity investments in publicly traded securities are based on quoted market prices in active markets, with no valuation adjustment. The fair value of equity securities without readily determinable fair values are initially valued at the transaction price and subsequently valued based upon a combination of entity-specific financial information and publicly available market information for similar companies that have actively traded equity securities.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Derivatives</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">All of our foreign currency forward derivative contracts have maturities of <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" format="ixt-sec:durwordsen" name="us-gaap:MaximumLengthOfTimeForeignCurrencyCashFlowHedge" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RleHRyZWdpb246MDBlOGE3MGFkYTlmNDA5Yzk4NTQ5YWNkM2NlMjA2NjBfMTkwNQ_6996dee3-8a8d-45f1-b012-21c3b7d4e126">three years</ix:nonNumeric> or less, and all are with counterparties that have minimum credit ratings of A&#8211; or equivalent by Standard &amp; Poor&#8217;s Financial Services LLC (S&amp;P), Moody&#8217;s Investors Service, Inc. (Moody&#8217;s) or Fitch Ratings, Inc. (Fitch). We estimate the fair values of these contracts by taking into consideration valuations obtained from a third-party valuation service that uses an income-based industry-standard valuation model for which all significant inputs are observable either directly or indirectly. These inputs include foreign currency exchange rates, LIBOR, swap rates and obligor credit default swap rates. In addition, inputs for our foreign currency option contracts include implied volatility measures. These inputs, when applicable, are at commonly quoted intervals. See Note 13, Derivative instruments.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our cross-currency swap contracts are with counterparties that have minimum credit ratings of A&#8211; or equivalent by S&amp;P, Moody&#8217;s or Fitch. We estimate the fair values of these contracts by taking into consideration valuations obtained from a third-party valuation service that uses an income-based industry-standard valuation model for which all significant inputs are observable either directly or indirectly. These inputs include foreign currency exchange rates, LIBOR, swap rates, obligor credit default swap rates and cross-currency-basis swap spreads. See Note 13, Derivative instruments.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our interest rate swap contracts are with counterparties that have minimum credit ratings of A&#8211; or equivalent by S&amp;P, Moody&#8217;s or Fitch. We estimate the fair values of these contracts by using an income-based industry-standard valuation model for which all significant inputs are observable either directly or indirectly. These inputs include LIBOR, swap rates and obligor credit default swap rates. See Note 13, Derivative instruments.</span></div></ix:continuation><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">21</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><ix:continuation id="iaee1e247e63640658b833843941f19cc"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">During the three and nine months ended September 30, 2021 and 2020, there were no material remeasurements to the fair values of assets and liabilities that are not measured at fair value on a recurring basis.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Summary of the fair values of other financial instruments</span></div><div style="margin-bottom:8pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Cash equivalents</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of cash equivalents approximate their carrying values due to the short-term nature of such financial instruments.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Borrowings</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We estimated the fair values of our borrowings by using Level 2 inputs. As of September 30, 2021 and December 31, 2020, the aggregate fair values of our borrowings were $<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:NotesPayableFairValueDisclosure" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RleHRyZWdpb246MDBlOGE3MGFkYTlmNDA5Yzk4NTQ5YWNkM2NlMjA2NjBfNDI4NA_8a55d0b1-7f03-49f7-9a93-5c2c67c9f1f9">42.2</ix:nonFraction> billion and $<ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:NotesPayableFairValueDisclosure" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RleHRyZWdpb246MDBlOGE3MGFkYTlmNDA5Yzk4NTQ5YWNkM2NlMjA2NjBfNDI5MQ_98b1e458-14d3-4907-a5f8-ad590ae2bee3">39.4</ix:nonFraction> billion, respectively, and the carrying values were $<ix:nonFraction unitRef="usd" contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:LongTermDebt" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RleHRyZWdpb246MDBlOGE3MGFkYTlmNDA5Yzk4NTQ5YWNkM2NlMjA2NjBfNDMzOA_3cdc1212-7b54-4c94-839c-0a0e0f94e940">37.6</ix:nonFraction> billion and $<ix:nonFraction unitRef="usd" contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:LongTermDebt" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RleHRyZWdpb246MDBlOGE3MGFkYTlmNDA5Yzk4NTQ5YWNkM2NlMjA2NjBfNDM0NQ_40efb6d8-8f5d-464a-a4b3-dde3810cf210">33.0</ix:nonFraction> billion, respectively.</span></div></ix:continuation><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_67"></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">13. <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfOTYxNQ_386c430b-4b8e-46c6-8f7f-dee62b496f29" continuedAt="i16538ad937b24e32b22c4eabb99acbb4" escape="true">Derivative instruments</ix:nonNumeric></span></div><ix:continuation id="i16538ad937b24e32b22c4eabb99acbb4" continuedAt="ie4d2f85d0cf44d9794801f51f496332b"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The Company is exposed to foreign currency exchange rate and interest rate risks related to its business operations. To reduce our risks related to such exposures, we use or have used certain derivative instruments, including foreign currency forward, cross-currency swap, forward interest rate and interest rate swap contracts. We do not use derivatives for speculative- trading purposes.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Cash flow hedges</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We are exposed to possible changes in the values of certain anticipated foreign currency cash flows resulting from changes in foreign currency exchange rates primarily associated with our euro-denominated international product sales. Increases and decreases in the cash flows associated with our international product sales due to movements in foreign currency exchange rates are partially offset by corresponding increases and decreases in the cash flows from our international operating expenses resulting from these foreign currency exchange rate movements. To further reduce our exposure to foreign currency exchange rate fluctuations with regard to our international product sales, we enter into foreign currency forward contracts to hedge a portion of our projected international product sales up to a maximum of three years into the future; and at any given point in time, a higher percentage of nearer-term projected product sales are being hedged than in successive periods.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">As of September 30, 2021 and December 31, 2020, we had outstanding foreign currency forward contracts with aggregate notional amounts of $<ix:nonFraction unitRef="usd" contextRef="i0d2698f3fe114fea898dbd1bedfa2f5c_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:DerivativeNotionalAmount" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfMTUwOQ_29697b04-8fc1-4196-bb92-daa82d45a51e">5.7</ix:nonFraction> billion and $<ix:nonFraction unitRef="usd" contextRef="i393a4aa6df064753bb52276e7ee04a5d_I20201231" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:DerivativeNotionalAmount" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfMTUxNg_082e671f-4cb9-4556-98f7-13efc628f789">5.1</ix:nonFraction> billion, respectively. We have designated these foreign currency forward contracts, which are primarily euro based, as cash flow hedges. Accordingly, we report the unrealized gains and losses on these contracts in AOCI in the Condensed Consolidated Balance Sheets, and we reclassify them to Product sales in the Condensed Consolidated Statements of Income in the same periods during which the hedged transactions affect earnings.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">To hedge our exposure to foreign currency exchange rate risk associated with certain of our long-term debt denominated in foreign currencies, we enter into cross-currency swap contracts. Under the terms of such contracts, we paid euros, pounds sterling and Swiss francs and received U.S. dollars for the notional amounts at the inception of the contracts; and based on these notional amounts, we exchange interest payments at fixed rates over the lives of the contracts by paying U.S. dollars and receiving euros, pounds sterling and Swiss francs. In addition, we will pay U.S. dollars to and receive euros, pounds sterling and Swiss francs from the counterparties at the maturities of the contracts for these same notional amounts. The terms of these contracts correspond to the related hedged debt, thereby effectively converting the interest payments and principal repayment on the debt from euros, pounds sterling and Swiss francs to U.S. dollars. We have designated these cross-currency swap contracts as cash flow hedges. Accordingly, the unrealized gains and losses on these contracts are reported in AOCI in the Condensed Consolidated Balance Sheets and reclassified to Other income, net, in the Condensed Consolidated Statements of Income in the same periods during which the hedged debt affects earnings.</span></div></ix:continuation><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">22</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><ix:continuation id="ie4d2f85d0cf44d9794801f51f496332b" continuedAt="ia46d4906c25a49e69c2f8b29a0a818aa"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="amgn:ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfOTU1NQ_fa267390-b298-4398-bc6b-442b85468104" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The notional amounts and interest rates of our cross-currency swaps as of September 30, 2021, were as follows (notional amounts in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:29.894%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.420%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.420%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.420%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.426%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Foreign currency</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S. dollars</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Hedged notes</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Notional amounts</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest rates</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Notional amounts</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest rates</span></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1.25% 2022 euro Notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8364;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="eur" contextRef="i7734e6b3c1704f4d8a988d1a61348a77_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DerivativeNotionalAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfMy0yLTEtMS0w_46af1c7a-9a82-4c04-b96f-08ff7e386219">1,250</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i399b619e02804ea2ba1db1e14f9ab716_I20210930" decimals="INF" name="us-gaap:DerivativeFixedInterestRate" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfMy00LTEtMS0w_f5d3a09a-60ea-4d28-8c74-c5948c724259">1.3</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7734e6b3c1704f4d8a988d1a61348a77_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DerivativeNotionalAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfMy02LTEtMS0w_1afbff94-6d23-4366-9aac-f2a1e0758410">1,388</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="ib1e612626d9f43b0b769e555166d81e3_I20210930" decimals="INF" name="us-gaap:DerivativeFixedInterestRate" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfMy04LTEtMS0w_fe47d4fb-669f-4e79-afc2-d546b125d81b">3.2</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">0.41% 2023 Swiss franc Bonds</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">CHF</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="chf" contextRef="ifc7f48af9c2b4b2681e9bd3d3af61b12_I20210930" decimals="-6" name="us-gaap:DerivativeNotionalAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNC0yLTEtMS0w_c1771bf7-be58-4c0f-bcf4-cb460a52680d">700</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="iba8a92586e2b4417a662a578f1511b3c_I20210930" decimals="INF" name="us-gaap:DerivativeFixedInterestRate" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNC00LTEtMS0w_d020cec9-6326-4c46-9f56-7e18a97656cf">0.4</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ifc7f48af9c2b4b2681e9bd3d3af61b12_I20210930" decimals="-6" name="us-gaap:DerivativeNotionalAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNC02LTEtMS0w_d2ad863b-e01d-4db0-a1a1-7769cc77f8b5">704</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i850f90a0299d43458bd33796e0371d13_I20210930" decimals="INF" name="us-gaap:DerivativeFixedInterestRate" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNC04LTEtMS0w_9abcc88b-8e60-4031-8bba-cd43c4aea62b">3.4</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.00% 2026 euro Notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8364;</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="eur" contextRef="i1ee3b6969d0e47798c3ab0adfa9e44d6_I20210930" decimals="-6" name="us-gaap:DerivativeNotionalAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNS0yLTEtMS0w_a1ae7dab-7f18-44a0-9d28-d7c1c93c2afe">750</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i3334c66245af46b9a585510eebce55e0_I20210930" decimals="INF" name="us-gaap:DerivativeFixedInterestRate" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNS00LTEtMS0w_d22db526-4fc1-4254-b0a9-c6c3e2711154">2.0</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1ee3b6969d0e47798c3ab0adfa9e44d6_I20210930" decimals="-6" name="us-gaap:DerivativeNotionalAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNS02LTEtMS0w_d783145e-dd0d-4b7b-8a97-8bdc323bcd0f">833</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="if435a46c948846aca4c19571c1f10bc9_I20210930" decimals="INF" name="us-gaap:DerivativeFixedInterestRate" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNS04LTEtMS0w_1c6ef3ac-63a8-43ec-ad6e-2ed5723916b0">3.9</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.50% 2026 pound sterling Notes</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#163;</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="gbp" contextRef="if10b3957b204438a86f3b2309e56842a_I20210930" decimals="-6" name="us-gaap:DerivativeNotionalAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNi0yLTEtMS0w_a13c4e1d-7d8c-461e-a3b1-0a992780bb84">475</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i5e8c12261fc243ddbd412fb565f1b116_I20210930" decimals="INF" name="us-gaap:DerivativeFixedInterestRate" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNi00LTEtMS0w_82effbc2-3dc4-4c48-867b-39e7bab7c2d0">5.5</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if10b3957b204438a86f3b2309e56842a_I20210930" decimals="-6" name="us-gaap:DerivativeNotionalAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNi02LTEtMS0w_f21efa09-9eab-49a6-a30c-3ac38a5c9f86">747</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="i603ad1820fef4e8a8f960404cd15b244_I20210930" decimals="INF" name="us-gaap:DerivativeFixedInterestRate" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNi04LTEtMS0w_96608682-d3ee-4fdd-a487-90fa609e396e">6.0</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.00% 2029 pound sterling Notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#163;</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="gbp" contextRef="id9403f32bf014bd1a180b462efe73171_I20210930" decimals="-6" name="us-gaap:DerivativeNotionalAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNy0yLTEtMS0w_1b99733f-a41c-4e5f-8da8-f218cb04347a">700</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="iece903822c1c413ba21f23e1a3a8817b_I20210930" decimals="INF" name="us-gaap:DerivativeFixedInterestRate" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNy00LTEtMS0w_78bf4de2-47c1-4b21-8429-7d7d122c6952">4.0</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id9403f32bf014bd1a180b462efe73171_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:DerivativeNotionalAmount" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNy02LTEtMS0w_7e8f46a4-4205-4563-bf27-c980c850375f">1,111</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="number" contextRef="if9749c18ee4d4475925e12e9fb9d6ec4_I20210930" decimals="INF" name="us-gaap:DerivativeFixedInterestRate" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNy04LTEtMS0w_1f3cbd86-46d8-4fc5-8a5c-09cc3e664c1b">4.5</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div></ix:nonNumeric><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#231f20;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In connection with the anticipated issuance of long-term fixed-rate debt, we occasionally enter into forward interest rate contracts in order to hedge the variability in cash flows due to changes in the applicable U.S. Treasury rate between the time we enter into these contracts and the time the related debt is issued. Gains and losses on forward interest rate contracts, which are designated as cash flow hedges, are recognized in AOCI i</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">n the Condensed Consolidated Balance Sheets </span><span style="color:#231f20;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">and are amortized into Interest expense, net, in the Condensed Consolidated Statements of Income over the lives of the associated debt issuances. Amounts recognized in connection with forward interest rate swaps during the nine months ended September 30, 2021, and amounts expected to be recognized during the subsequent 12 months are not material.</span></div><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfOTU4OA_f3ec2d0f-9acd-4817-a6a2-d67f70df46de" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The unrealized gains and losses recognized in AOCI for our derivative instruments designated as cash flow hedges were as follows (in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:45.245%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.619%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.619%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.473%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.624%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivatives in cash flow hedging relationships</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia82e4d4dd7624199b0b9823339e7521e_D20210701-20210930" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMi0yLTEtMS0w_36f77d38-21b1-494c-bd53-b8ff1a6cb548">136</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="idfede3337ef54161bc5bd47fd541f5ef_D20200701-20200930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMi00LTEtMS0w_13ec2e4c-a928-4ab9-9ecc-70a992fa789d">163</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="icc5c639f364e45baa662901e97a7de40_D20210101-20210930" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMi02LTEtMS0w_bccc045b-03cd-4288-bbeb-c31cb7ee94a5">273</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i01d039e9716e4293aacd1732c82a9104_D20200101-20200930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMi04LTEtMS0w_93d7d777-bd7a-4398-869f-346c0195a0c9">25</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i429f2cf41442431d854b0802e1818b63_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMy0yLTEtMS0w_fae9bff0-f15a-4ff7-8d02-e62678abb64d">120</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if6773803670d44b2ae4b1519c9996aac_D20200701-20200930" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMy00LTEtMS0w_0923f3bb-a640-4a4a-a368-e6de884dff89">223</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5c44b32339c742969f187797f4ae3956_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMy02LTEtMS0w_a5797152-29af-468f-9cd9-6d7c0a98162a">180</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="icb1c3e075c0447c0a8d96118c3b1ccc0_D20200101-20200930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMy04LTEtMS0w_672ca9da-f4e4-4ebb-b18a-796a790d5c66">107</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 14.5pt;text-align:left;text-indent:-4.5pt;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total unrealized gains (losses)</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i53af41683cb14e598e98d0cdd138caeb_D20210701-20210930" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfNS0yLTEtMS0w_30a4949a-a882-4e59-b2e8-80eb5c9e6c4f">16</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i9a23429c3e7047b1be61aaf1c0cd68ff_D20200701-20200930" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfNS00LTEtMS0w_0a1897ec-3b91-49a3-a685-81e7a2a03297">60</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i4dfa001ded2a48d2a902aa13f44f8684_D20210101-20210930" decimals="-6" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfNS02LTEtMS0w_e979382c-70fa-4c5f-bcef-1c7b468ead37">93</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i3253252da82e4f4cb4e51fe1f6a14b85_D20200101-20200930" decimals="-6" sign="-" name="us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfNS04LTEtMS0w_049b1e3f-5d52-496a-9712-842c2ab7ceb0">132</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div></ix:nonNumeric><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Fair value hedges</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">To achieve a desired mix of fixed-rate and floating-rate debt, we entered into interest rate swap contracts that qualified for and were designated as fair value hedges. These interest rate swap contracts effectively convert fixed-rate coupons to floating-rate LIBOR-based coupons over the terms of the related hedge contracts. As of September 30, 2021 and December 31, 2020, we had interest rate swap contracts with aggregate notional amounts of $<ix:nonFraction unitRef="usd" contextRef="i5d9649b14f6944e6b32f46773afd94df_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:DerivativeNotionalAmount" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNDc0OQ_b4c4cf55-0b87-408a-ac66-2d8c378429cd">7.4</ix:nonFraction>&#160;billion and $<ix:nonFraction unitRef="usd" contextRef="i93734d89c57d45e99c00e58787a09f5e_I20201231" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:DerivativeNotionalAmount" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNDc1Ng_3e581e6b-acf6-4d54-b713-ef00e3d52f6d">5.9</ix:nonFraction> billion, respectively, that hedge certain portions of our long-term debt issuances. During the three months ended June 30, 2021, we entered into $<ix:nonFraction unitRef="usd" contextRef="ifb6251f8399b4dc69935ab1011467098_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:DerivativeNotionalAmount" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNDg5Ng_5290d673-bfc0-40d1-a026-8c62b0aeea8c">1.5</ix:nonFraction>&#160;billion of interest rate swap contracts to hedge portions of our <ix:nonFraction unitRef="number" contextRef="ia3569d0c6bcd4203a1148cb8dda584fe_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNDk1Ng_a4b8ca7f-f36f-413c-ac9b-f3a3eaece057">2.45</ix:nonFraction>% 2030 Notes and <ix:nonFraction unitRef="number" contextRef="i2c54babb8e9f4eb8b43722a88181da66_I20210930" decimals="INF" name="us-gaap:DebtInstrumentInterestRateStatedPercentage" scale="-2" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNDk3NA_64ecda43-17f2-4649-b094-6426591c3723">2.30</ix:nonFraction>% 2031 Notes (see Note 10, Financing arrangements).</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">For interest rate swap contracts that qualify for and are designated as fair value hedges, we recognize in Interest expense, net, in the Condensed Consolidated Statements of Income the unrealized gain or loss on the derivative resulting from the change in fair value during the period, as well as the offsetting unrealized loss or gain of the hedged item resulting from the change in fair value during the period attributable to the hedged risk. If a hedging relationship involving an interest rate swap contract is terminated, the gain or loss realized on contract termination is recorded as an adjustment to the carrying value of the debt and amortized into Interest expense, net, over the remaining life of the previously hedged debt.</span></div></ix:continuation><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">23</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><ix:continuation id="ia46d4906c25a49e69c2f8b29a0a818aa" continuedAt="i21fe634f6bef4d06807720d7aa6e7ac9"><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfOTU5OQ_03c8ff6e-7f0e-496a-867c-cb95a52a4eac" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The hedged liabilities and related cumulative-basis adjustments for fair value hedges of those liabilities were recorded in the Condensed Consolidated Balance Sheets as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:37.496%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:13.519%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:13.519%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:13.519%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:13.527%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Carrying amounts of hedged liabilities</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:5.2pt;font-weight:700;line-height:100%;position:relative;top:-2.8pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Cumulative amounts of fair value hedging adjustments related to the carrying amounts of the hedged liabilities</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:5.2pt;font-weight:700;line-height:100%;position:relative;top:-2.8pt;vertical-align:baseline">(2)</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated Balance Sheets locations</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Current portion of long-term debt</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i44869b7e4ad641a5bc2667496e4c4b2c_I20210930" decimals="-6" name="us-gaap:HedgedLiabilityFairValueHedge" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMi0yLTEtMS0w_479b2393-f33d-4957-aec4-dd948e50d3ce">840</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia18546e9b5354e3da7193d7dab9c11f3_I20201231" decimals="-6" name="us-gaap:HedgedLiabilityFairValueHedge" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMi00LTEtMS0w_2ec8a0a4-7a2c-4b6e-a3f4-8f9044145a0d">89</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i44869b7e4ad641a5bc2667496e4c4b2c_I20210930" decimals="-6" name="us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMi02LTEtMS0w_409d41ea-320c-4eec-9164-1ae6eeb88dce">90</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ia18546e9b5354e3da7193d7dab9c11f3_I20201231" decimals="-6" name="us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMi04LTEtMS0w_9725522b-2736-47fc-8981-7b36b36987b5">89</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Long-term debt</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i040b7e3625734005983b800042806116_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:HedgedLiabilityFairValueHedge" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMy0yLTEtMS0w_4132880b-54a8-4760-84bd-7f74501e4017">6,809</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if82a04ddb1484b4d9d685c69534d60ee_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:HedgedLiabilityFairValueHedge" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMy00LTEtMS0w_a290e73e-7bdc-475a-9246-022d8ae8c5c5">6,258</ix:nonFraction>&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i040b7e3625734005983b800042806116_I20210930" decimals="-6" name="us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMy02LTEtMS0w_f4ac1012-bc8c-4256-af1f-f1b7481f7894">281</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="if82a04ddb1484b4d9d685c69534d60ee_I20201231" decimals="-6" name="us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMy04LTEtMS0w_8779c9b9-d9c7-4736-8dc5-3edb9f066d0d">477</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-top:7pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">____________</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> &#160;&#160;&#160;&#160;Current portion of long-term debt includes $<ix:nonFraction unitRef="usd" contextRef="i44869b7e4ad641a5bc2667496e4c4b2c_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:HedgedLiabilityDiscontinuedFairValueHedge" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNjAyMA_3ab4a755-519f-4181-a9a7-61eefb39fbef">87</ix:nonFraction> million and $<ix:nonFraction unitRef="usd" contextRef="ia18546e9b5354e3da7193d7dab9c11f3_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="amgn:HedgedLiabilityDiscontinuedFairValueHedge" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNzY5NjU4MTQwNDE1OQ_164682f5-3dab-4f7c-b1bd-5556048bc20a">89</ix:nonFraction>&#160;million of carrying value with discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively. Long-term debt includes $<ix:nonFraction unitRef="usd" contextRef="i040b7e3625734005983b800042806116_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="amgn:HedgedLiabilityDiscontinuedFairValueHedge" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNjE0Mg_86fe4381-1207-471e-a852-f91e804a0ee9">460</ix:nonFraction> million and $<ix:nonFraction unitRef="usd" contextRef="if82a04ddb1484b4d9d685c69534d60ee_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="amgn:HedgedLiabilityDiscontinuedFairValueHedge" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNjE0OQ_489dfccb-e115-4a6a-9259-cfd6a77b26af">525</ix:nonFraction> million of carrying value with discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively.</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">(2)</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;Current portion of long-term debt includes $<ix:nonFraction unitRef="usd" contextRef="i44869b7e4ad641a5bc2667496e4c4b2c_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNjI4OA_1588cf9c-9cd1-409a-9b22-873a76983b24">87</ix:nonFraction> million and $<ix:nonFraction unitRef="usd" contextRef="ia18546e9b5354e3da7193d7dab9c11f3_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNzY5NjU4MTQwNDE0Ng_b0bcbd7c-7793-44bc-838c-fde7ef26e3c9">89</ix:nonFraction>&#160;million of hedging adjustments on discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively. Long-term debt includes $<ix:nonFraction unitRef="usd" contextRef="i040b7e3625734005983b800042806116_I20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNjQxMw_8f500ae4-525e-4b44-8740-02483ddcb49a">360</ix:nonFraction> million and $<ix:nonFraction unitRef="usd" contextRef="if82a04ddb1484b4d9d685c69534d60ee_I20201231" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNjQyMA_ef2ee5ad-7955-4a73-9429-2a297bb0ec37">425</ix:nonFraction> million of hedging adjustments on discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively.</span></div></ix:nonNumeric></ix:continuation><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span><br/></span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">24</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><ix:continuation id="i21fe634f6bef4d06807720d7aa6e7ac9" continuedAt="i7de889496d2c485d974ac8c08037524b"><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Impact of hedging transactions</span></div><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfOTU5MA_d736f285-def6-41fe-8362-e8b3a1a1f96c" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The following tables summarize the amounts recorded in income and expense line items and the effects thereon from fair value and cash flow hedging, including discontinued hedging relationships (in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.561%"><tr><td style="width:1.0%"></td><td style="width:40.309%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.710%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.710%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.151%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.710%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.151%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.155%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended September 30, 2021</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Product sales</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other income, net</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest expense, net</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Product sales</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other income, net</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest expense, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total amounts recorded in income and (expense) line items presented in the Condensed Consolidated Statements of Income</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i237db287808149dc88791dd0402e8c8d_D20210701-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMy0yLTEtMS0w_ff29ea1e-ea60-4f6a-8628-3606bbd07914">6,320</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMy00LTEtMS0w_50f25787-f8b7-4286-9223-104aac7a2f6a">73</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930" decimals="-6" name="us-gaap:InterestExpenseDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMy02LTEtMS0w_60beef6d-075a-4780-b2c3-135950e20e71">296</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3eb445431b634cc6b3e61727cef7b877_D20210101-20210930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMy04LTEtMS0w_16c8f25e-7b9e-4696-8116-e3fe10888409">18,026</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMy0xMC0xLTEtMA_a6b453ed-7e85-4974-b7c2-ea074d62dfe9">97</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" decimals="-6" name="us-gaap:InterestExpenseDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMy0xMi0xLTEtMA_33730618-6b0c-40e4-bf6b-43e3fdd300e2">862</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">The effects of cash flow and fair value hedging:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Losses on cash flow hedging relationships reclassified out of AOCI:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i189a6a6830c84033985ac2eb0166844f_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfNi0yLTEtMS0w_e96719db-e1c7-4879-9f10-71bf00edc9d8">5</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i84ce59b928bc4625b81e9ba243566b0b_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfNi04LTEtMS0w_660f36ba-353e-4b34-ba66-15596b9dfede">24</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i44310cb41e2e4aaabf0dc581c8c2c4ea_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfNy00LTEtMS0w_ff0c280c-0988-4944-90ff-c1337c9e702e">104</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2b29edf642674757a33b45fcec1cc8b4_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfNy0xMC0xLTEtMA_cb39aac0-e0bb-4fb0-9a28-ec8576d37dc6">190</ix:nonFraction>)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Gains (losses) on fair value hedging relationships&#8212;interest rate swap agreements:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:11.25pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Hedged items</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="icc69b7bd76f6439ea5993cfe7cab843b_D20210701-20210930" decimals="-6" name="us-gaap:ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMTAtNi0xLTEtMA_4b76b8a7-1f92-4288-bb91-16b7e4ba617c">54</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i2368706943c748edb9e18c4bf06ef9ad_D20210101-20210930" decimals="-6" name="us-gaap:ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMTAtMTItMS0xLTA_e0f13045-16d7-4d87-954b-35353551a39e">195</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives designated as hedging instruments</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="icc69b7bd76f6439ea5993cfe7cab843b_D20210701-20210930" decimals="-6" sign="-" name="us-gaap:ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMTEtNi0xLTEtMA_01033cff-e7e3-4e02-aff4-bf2e0b886754">31</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i2368706943c748edb9e18c4bf06ef9ad_D20210101-20210930" decimals="-6" sign="-" name="us-gaap:ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMTEtMTItMS0xLTA_a88353fb-ed7f-4d91-8c7a-e0091f33d181">128</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div><span><br/></span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.561%"><tr><td style="width:1.0%"></td><td style="width:40.309%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.710%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.151%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.151%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.710%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.710%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.534%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.155%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended September 30, 2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended September 30, 2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Product sales</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other income, net</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest expense, net</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Product sales</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other income, net</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest expense, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total amounts recorded in income and (expense) line items presented in the Condensed Consolidated Statements of Income</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="icc3aae43096e4ee2941dfecfdc9776ad_D20200701-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMy0yLTEtMS0w_5c20c93e-45a0-43e1-aad8-369b7e18c3c6">6,104</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMy00LTEtMS0w_fc7c6426-e226-4770-a569-b617c3f6a612">55</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930" decimals="-6" name="us-gaap:InterestExpenseDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMy02LTEtMS0w_366316c7-ff2b-40a9-a2dc-80781b7d695a">302</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i556e038dae96477cbe84bc1653ed5883_D20200101-20200930" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMy04LTEtMS0w_533cab51-3c88-4291-849e-212c66973fdb">17,906</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMy0xMC0xLTEtMA_aaa5c8a8-3684-4790-8977-73e23e7a0b08">69</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930" decimals="-6" name="us-gaap:InterestExpenseDebt" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMy0xMi0xLTEtMA_a63d2d76-b257-41a6-ae59-bbefefcfe7fc">944</ix:nonFraction>)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">The effects of cash flow and fair value hedging:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Gains on cash flow hedging relationships reclassified out of AOCI:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ieccef0ffb45a4fdcbd44c752c16e6068_D20200701-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfNi0yLTEtMS0w_4394ae65-2f39-4a83-838e-55ef6401a965">41</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i503ef52a14c747cb9fab04a1e85b81d1_D20200101-20200930" decimals="-6" name="us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfNi04LTEtMS0w_2dcf81c5-9dfc-4c1a-9396-a59bae34cd79">158</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iaef608c4412a4e94ba0fb53cc211b333_D20200701-20200930" decimals="-6" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfNy00LTEtMS0w_63291c89-6652-4542-80a0-fd5fe8cc5b50">183</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i1da13ce0b09e46ae9200663802380083_D20200101-20200930" decimals="-6" name="us-gaap:NonoperatingIncomeExpense" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfNy0xMC0xLTEtMA_f1a877c4-f710-4557-abd7-945cbcc22233">101</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Gains (losses) on fair value hedging relationships&#8212;interest rate swap agreements:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:11.25pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Hedged items</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i7c59c26b885d420cbebeaff7c5823719_D20200701-20200930" decimals="-6" name="us-gaap:ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMTAtNi0xLTEtMA_aa390963-4ab4-4a4a-90b8-1f19d464c5d1">35</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ife3621a3597c4b819c57657a0cacdc1d_D20200101-20200930" decimals="-6" name="us-gaap:ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMTAtMTItMS0xLTA_ba14934d-6abf-48ea-8259-3ed0ff735fa2">215</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives designated as hedging instruments</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="i7c59c26b885d420cbebeaff7c5823719_D20200701-20200930" decimals="-6" sign="-" name="us-gaap:ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMTEtNi0xLTEtMA_a72ec516-54fd-4848-b89f-d6e0991fee57">13</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(<ix:nonFraction unitRef="usd" contextRef="ife3621a3597c4b819c57657a0cacdc1d_D20200101-20200930" decimals="-6" sign="-" name="us-gaap:ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMTEtMTItMS0xLTA_054ec489-8b54-4107-bfa9-dcf3b8beb9ec">150</ix:nonFraction>)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">__________</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;Gains on hedged items do not exactly offset losses on the related designated hedging instruments due to amortization of the cumulative amounts of fair value hedging adjustments included in the carrying amount of the hedged debt for discontinued hedging relationships and the recognition of gains on terminated hedges when the corresponding hedged item was paid down in the period.</span></div></ix:nonNumeric><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">No portions of our cash flow hedge contracts were excluded from the assessment of hedge effectiveness. As of September 30, 2021, the net gains expected to be reclassified on our foreign currency and cross-currency swap contracts out of AOCI and into earnings during the next 12 months are not material.</span></div></ix:continuation><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">25</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><ix:continuation id="i7de889496d2c485d974ac8c08037524b"><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Derivatives not designated as hedges</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">To reduce our exposure to foreign currency fluctuations in certain assets and liabilities denominated in foreign currencies, we enter into foreign currency forward contracts that are not designated as hedging transactions. Most of these exposures are hedged on a month-to-month basis. As of September 30, 2021 and December 31, 2020, the total notional amounts of these foreign currency forward contracts were $<ix:nonFraction unitRef="usd" contextRef="i6967f808be0e42dd8d431bf91fbf8fda_I20210930" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:DerivativeNotionalAmount" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNzg1OA_43c96355-8251-46e5-8a7b-4efdc2007d89">0.7</ix:nonFraction> billion and $<ix:nonFraction unitRef="usd" contextRef="icf8902c539da490aa8f154995bfad656_I20201231" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:DerivativeNotionalAmount" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNzg2NQ_c5382435-a734-402d-bd87-874479fa37b8">1.0</ix:nonFraction> billion, respectively. Gains and losses recognized in earnings for our derivative instruments not designated as hedging instruments were not material for the three and nine months ended September 30, 2021 and 2020. </span></div><ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfOTU4MA_a3ae4b51-39e6-40f2-bcb0-eca1eb4c5024" escape="true"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of derivatives included in the Condensed Consolidated Balance Sheets were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:37.496%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:18.344%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.695%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:18.344%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.701%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivative assets</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivative liabilities</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Balance Sheets locations</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair&#160;values</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Balance Sheets locations</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair&#160;values</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivatives designated as hedging&#160;instruments:</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i3847de63b915449dacb3fe5ac480d2d4_I20210930" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeAsset" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfMy00LTEtMS0w_c06744db-81d8-4214-ac2f-2fe38d86f6f0">127</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other&#160;noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i6dd8345dd5db4bef839be567148829c8_I20210930" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfMy04LTEtMS0w_f3c622d9-39b2-4fd4-8117-c60d8bed81b2">54</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i66933df39b94465f8542b2c374051858_I20210930" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeAsset" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfNC00LTEtMS0w_bd0b92e8-4338-4501-be35-2128002cdc3f">119</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other&#160;noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="iae17d6c368384d6081046e9199b88942_I20210930" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfNC04LTEtMS0w_44c2499c-c218-4e1e-be3d-f1b17a82a0ed">360</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i6dc0acd554d1417d8ee9828564a05a4d_I20210930" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeAsset" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfNS00LTEtMS0w_db5f28ac-6700-458e-a74a-5801d13b6009">29</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other&#160;noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="id9f3f0d26a574ed0a5c0ee09137be2a1_I20210930" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfNS04LTEtMS0w_bc85ddd4-f330-42aa-8946-8422a77994a5">105</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total derivatives designated as hedging instruments</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic5f888563c394d598153a924bfacbca4_I20210930" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeAsset" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfNy00LTEtMS0w_820827ad-ab03-455e-b302-e7afcf397f3b">275</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ic5f888563c394d598153a924bfacbca4_I20210930" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfNy04LTEtMS0w_9e2c8815-094e-463f-ba12-41d6aff42dd9">519</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div><div><span><br/></span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:37.496%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:18.344%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.695%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:18.344%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:8.701%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivative assets</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivative liabilities</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Balance Sheets locations</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair&#160;values</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Balance Sheets locations</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair&#160;values</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivatives designated as hedging instruments:</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i78df11bae6c9411f901b63b66ef4b7d7_I20201231" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeAsset" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfMy00LTEtMS0w_3d258ed3-4550-401b-9364-5d3102b0f96d">28</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i03f545cb57bd498bb5e65da04d641b83_I20201231" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfMy04LTEtMS0w_69d13c4f-27a6-4e54-8039-ad10faac0652">237</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ie0dc252346c94bbc92e44b537f39ccd3_I20201231" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeAsset" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfNC00LTEtMS0w_ca93795f-5957-4532-bfb5-c5b65ebf9d9a">255</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i91c7206f80d44590a0419f271b3f7a9e_I20201231" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfNC04LTEtMS0w_4c0f76c1-0d25-498f-bc87-38c2f5db21ee">318</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i44a11e7c427b47569c640463a3089cf8_I20201231" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeAsset" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfNi00LTEtMS0w_4fd77662-9157-4276-b2d3-b8c7f2d0cf43">66</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="ide90c3477b63435f97b32f9aba190c02_I20201231" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfNi04LTEtMS0w_059b83af-ada9-4937-b6da-f99ef6697b4f">15</ix:nonFraction>&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total derivatives designated as hedging instruments</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i76a5a06206924308b632f5ca3c34bd97_I20201231" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeAsset" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfNy00LTEtMS0w_79b72382-d867-40b0-ade4-f983a0fb59d5">349</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"><ix:nonFraction unitRef="usd" contextRef="i76a5a06206924308b632f5ca3c34bd97_I20201231" decimals="-6" name="us-gaap:DerivativeFairValueOfDerivativeLiability" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfNy04LTEtMS0w_5b45e0bc-6878-4b2f-91c4-ffbc6d14bc4f">570</ix:nonFraction>&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div></ix:nonNumeric><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our derivative contracts that were in liability positions as of September 30, 2021, contain certain credit-risk-related contingent provisions that would be triggered if (i)&#160;we were to undergo a change in control and (ii)&#160;our or the surviving entity&#8217;s creditworthiness deteriorates, which is generally defined as having either a credit rating that is below investment grade or a materially weaker creditworthiness after the change in control. If these events were to occur, the counterparties would have the right, but not the obligation, to close the contracts under early-termination provisions. In such circumstances, the counterparties could request immediate settlement of these contracts for amounts that approximate the then current fair values of the contracts. In addition, our derivative contracts are not subject to any type of master netting arrangement, and amounts due either to or from a counterparty under the contracts may be offset against other amounts due either to or from the same counterparty only if an event of default or termination, as defined, were to occur.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The cash flow effects of our derivative contracts in the Condensed Consolidated Statements of Cash Flows are included in Net cash provided by operating activities, except for the settlement of notional amounts of cross-currency swaps, which are included in Net cash used in financing activities.</span></div></ix:continuation><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">26</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_70"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">14. <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:CommitmentsAndContingenciesDisclosureTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83MC9mcmFnOjZmMzVmMjIzNjJhNzQwNjliZWM5MjRhMGNmOTY0NjdmL3RleHRyZWdpb246NmYzNWYyMjM2MmE3NDA2OWJlYzkyNGEwY2Y5NjQ2N2ZfOTA0OA_cdb77063-7d7e-4a32-96c8-00ca7004949e" continuedAt="icc6890b3d4c34ce1a56fa288abc44c43" escape="true">Contingencies and commitments</ix:nonNumeric></span></div><ix:continuation id="icc6890b3d4c34ce1a56fa288abc44c43" continuedAt="ife0d639a54764abf8286101fb15ac47c"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Contingencies</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In the ordinary course of business, we are involved in various legal proceedings, government investigations and other matters that are complex in nature and have outcomes that are difficult to predict. See our Annual Report on Form 10-K for the year ended December 31, 2020, Part I, Item 1A. Risk Factors&#8212;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Our business may be affected by litigation and government investigations. </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We describe our legal proceedings and other matters that are significant or that we believe could become significant in this footnote; in Note 19, Contingencies and commitments, to the consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2020; in Note 12, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended March 31, 2021; and in Note 13, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended June 30, 2021.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We record accruals for loss contingencies to the extent that we conclude it is probable that a liability has been incurred and the amount of the related loss can be reasonably estimated. We evaluate, on a quarterly basis, developments in legal proceedings and other matters that could cause an increase or decrease in the amount of the liability that has been accrued previously.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our legal proceedings involve various aspects of our business and a variety of claims, some of which present novel factual allegations and/or unique legal theories. In each of the matters described in this filing; in Note 19, Contingencies and commitments, to the consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2020; in Note 12, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended March 31, 2021; or in Note 13, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended June 30, 2021, in which we could incur a liability, our opponents seek an award of a not-yet-quantified amount of damages or an amount that is not material. In addition, a number of the matters pending against us are at very early stages of the legal process, which in complex proceedings of the sort we face often extend for several years. As a result, none of the matters described in this filing; in Note 19, Contingencies and commitments, to the consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2020; in Note 12, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended March 31, 2021; or in Note 13, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended June 30, 2021, in which we could incur a liability, have progressed sufficiently through discovery and/or the development of important factual information and legal issues to enable us to estimate a range of possible loss, if any, or such amounts are not material. While it is not possible to accurately predict or determine the eventual outcomes of these matters, an adverse determination in one or more of these matters currently pending could have a material adverse effect on our consolidated results of operations, financial position or cash flows.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Certain recent developments concerning our legal proceedings and other matters are discussed below:</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Abbreviated New Drug Application (ANDA) Patent Litigation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"> ANDA Patent Litigation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Amgen Inc. v. Sandoz Inc., et al.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On September 28, 2021, consistent with its September 20, 2021 opinion and order, the U.S. District Court for the District of New Jersey (the New Jersey District Court) entered final judgment in favor of Amgen and against Zydus Pharmaceuticals (USA) Inc. (Zydus) with respect to claims 3 and 6 of U.S. Patent No. 7,427,638 (the &#8217;638 Patent), claim 6 of U.S. Patent No. 8,455,536 (the &#8217;536 Patent) and claims 2 and 27 of U.S. Patent No. 8,093,283 (the &#8216;283 Patent); and final judgment in favor of Zydus and against Amgen with respect to claims 1 and 15 of U.S. Patent No. 7,893,101 (the &#8216;101 Patent) and claims 2, 19 and 21 of U.S. Patent No. 10,092,541 (the &#8217;541 Patent). The final judgment ordered that the effective date of any final approval by the U.S. Food and Drug Administration (FDA) of Zydus&#8217;s ANDA must be after expiration of the <ix:nonFraction unitRef="patent" contextRef="i2cc9eff2f67a40c98702116571cdb627_D20210928-20210928" decimals="INF" format="ixt-sec:numwordsen" name="us-gaap:GainContingencyPatentsFoundInfringedUponNumber" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83MC9mcmFnOjZmMzVmMjIzNjJhNzQwNjliZWM5MjRhMGNmOTY0NjdmL3RleHRyZWdpb246NmYzNWYyMjM2MmE3NDA2OWJlYzkyNGEwY2Y5NjQ2N2ZfNzY5NjU4MTQzOTg5Mg_91efbe2e-7dc6-423c-b65d-167cbc96a344">three</ix:nonFraction> infringed patents (the &#8217;638, &#8217;536 and &#8217;283 Patents) and any regulatory exclusivity to which Amgen may become entitled. The final judgment also includes an injunction prohibiting Zydus from making, using, offering to sell, or selling in the United States, or importing into the United States, Zydus&#8217;s generic apremilast products during the term of the three infringed patents. </span></div></ix:continuation><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">27</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><ix:continuation id="ife0d639a54764abf8286101fb15ac47c" continuedAt="i032361c68b6340319bb1baf1cb79ad4d"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On October 12, 2021, the New Jersey District Court also entered final judgment in favor of Amgen and against Sandoz Inc. (Sandoz) with respect to claims 3 and 6 of the &#8217;638 Patent, claim 6 of the &#8217;536 Patent and claims 1 and 15 of the &#8217;101 Patent; and final judgment in favor of Sandoz and against Amgen with respect to claims 2, 19 and 21 of the &#8217;541 Patent. The final judgment ordered that the effective date of any final approval by the FDA of Sandoz&#8217;s ANDA must be after expiration of the <ix:nonFraction unitRef="patent" contextRef="idaf73178159c45d5ba7f7dde88688204_D20211012-20211012" decimals="INF" format="ixt-sec:numwordsen" name="us-gaap:GainContingencyPatentsFoundInfringedUponNumber" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83MC9mcmFnOjZmMzVmMjIzNjJhNzQwNjliZWM5MjRhMGNmOTY0NjdmL3RleHRyZWdpb246NmYzNWYyMjM2MmE3NDA2OWJlYzkyNGEwY2Y5NjQ2N2ZfNzY5NjU4MTQzOTg5Mw_e67f6a26-5a4c-4d5b-be8c-3deb0619eb95">three</ix:nonFraction> infringed patents (the &#8217;638, &#8217;536 and &#8217;101 Patents) and any regulatory exclusivity to which Amgen may become entitled. The final judgment also includes an injunction prohibiting Sandoz from making, using, offering to sell, or selling in the United States, or importing into the United States, Sandoz&#8217;s generic apremilast products during the term of the <ix:nonFraction unitRef="patent" contextRef="idaf73178159c45d5ba7f7dde88688204_D20211012-20211012" decimals="INF" format="ixt-sec:numwordsen" name="us-gaap:GainContingencyPatentsFoundInfringedUponNumber" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83MC9mcmFnOjZmMzVmMjIzNjJhNzQwNjliZWM5MjRhMGNmOTY0NjdmL3RleHRyZWdpb246NmYzNWYyMjM2MmE3NDA2OWJlYzkyNGEwY2Y5NjQ2N2ZfNzY5NjU4MTQzOTg5NA_575302b2-7fca-40e9-a417-b6bfc9116c70">three</ix:nonFraction> infringed patents.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Zydus and Amgen filed notices of appeal to the U.S. Court of Appeals for the Federal Circuit (the Federal Circuit Court) on October 27, 2021 and October 28, 2021, respectively.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Sensipar</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">(cinacalcet) ANDA Patent Litigation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Amgen Inc. v. Amneal Pharmaceuticals LLC, et al. (formerly, Amgen Inc. v. Aurobindo Pharma Ltd. et al.) </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On October 20, 2021, the U.S. District Court for the District of Delaware (the Delaware District Court) issued final judgment in favor of Piramal Healthcare UK Limited and Slate Run Pharmaceuticals LLC.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">ENBREL Patent Litigation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Immunex Corporation, et al. v. Samsung Bioepis Co., Ltd.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On November 2, 2021, Amgen and Samsung Bioepis Co., Ltd. (Bioepis), with the consent of Hoffmann-La Roche Inc. (Roche), jointly submitted to the New Jersey District Court a confidential stipulation and a form of final judgment and order of permanent injunction resolving the dispute between the parties and enjoining Bioepis from making, using, offering to sell, or selling within the United States, or importing into the United States, any product containing etanercept until the April 24, 2029 expiry of Roche&#8217;s U.S. Patent No. 8,163,522.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"> Patent Litigation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Patent Disputes in the International Region</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">National litigations in the United Kingdom, France, the Netherlands and Italy have been settled. In Germany, Sanofi-Aventis Deutschland GmbH and Regeneron Pharmaceuticals, Inc. have filed actions claiming they are entitled to damages arising from the provisional enforcement of an injunction against PRALUENT</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.47pt;font-weight:400;line-height:120%;position:relative;top:-3.48pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">that was lifted after the European Patent Office Technical Board of Appeal&#8217;s October 29, 2020 ruling that certain claims encompassing PRALUENT</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.47pt;font-weight:400;line-height:120%;position:relative;top:-3.48pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> in Amgen&#8217;s European Patent No. 2,215,124 were invalid.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">NEUPOGEN</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"> (filgrastim)/Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"> Patent Litigation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Amgen Inc., et al. v. Pfizer Inc. et al.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On September 8, 2021, pursuant to joint stipulation, the Delaware District Court dismissed the lawsuits regarding U.S. Patent Nos. 9,643,997 and 10,577,392.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Patent Trial and Appeal Board (PTAB) Challenge</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Apotex PTAB Challenge</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On September 2, 2021, the Federal Circuit Court issued a remand to permit Amgen to request rehearing of the PTAB&#8217;s final written decision holding that all claims of U.S. Patent No. 8.952,138 as unpatentable.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Pfizer PTAB Challenge</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On February 10, 2021, Hospira, Inc. and Pfizer Inc. (collectively, Pfizer) filed a petition to institute inter partes review (IPR) proceeding at the U.S. Patent and Trademark Office (USPTO) of U.S. Patent No. 8,273,707 (the &#8217;707 Patent), challenging claims of the &#8217;707 Patent as unpatentable. Amgen&#8217;s preliminary response was filed on May 18, 2021.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On August 17, 2021, the PTAB of the USPTO granted Pfizer&#8217;s petition to institute IPR of the &#8217;707 Patent. On August 23, 2021, the PTAB issued the schedule for the proceeding, including oral argument (if requested) on May 18, 2022. </span></div></ix:continuation><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">28</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><ix:continuation id="i032361c68b6340319bb1baf1cb79ad4d"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Breach of Contract Action</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Novartis Pharma AG v. Amgen Inc.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On October 26, 2021, the U.S. District Court for the Southern District of New York held a status conference with the parties and set the dates for Novartis Pharma AG&#8217;s (Novartis) opening brief for its motion for partial summary judgment on <ix:nonFraction unitRef="claim" contextRef="i7e4af91b19174262910dae2ac9317e09_I20211026" decimals="INF" format="ixt-sec:numwordsen" name="us-gaap:LossContingencyPendingClaimsNumber" scale="0" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83MC9mcmFnOjZmMzVmMjIzNjJhNzQwNjliZWM5MjRhMGNmOTY0NjdmL3RleHRyZWdpb246NmYzNWYyMjM2MmE3NDA2OWJlYzkyNGEwY2Y5NjQ2N2ZfODI0NjMzNzI1NDE0MQ_2741fd6e-ee32-49c1-8aa7-ec06f019bb04">two</ix:nonFraction> claims, fraudulent inducement and negligent misrepresentation, to be due on January 14, 2022, Amgen&#8217;s opposition to be due on February 14, 2022 and Novartis&#8217; reply to be due on March 10, 2022. This motion, if granted, will not dispose of the entire case as other claims related to breach of contract remain pending.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">U.S. Tax Litigation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Amgen Inc. &amp; Subsidiaries v. Commissioner of Internal Revenue</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">See Note 4, Income taxes, for discussion of the IRS tax dispute and the Company&#8217;s petition in the U.S. Tax Court.</span></div></ix:continuation><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_73"></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">15. <ix:nonNumeric contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930" name="us-gaap:SubsequentEventsTextBlock" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83My9mcmFnOjlhYzgyOGNkN2E5ODQ2NzdiMDJiZjExNThmN2RjNGRhL3RleHRyZWdpb246OWFjODI4Y2Q3YTk4NDY3N2IwMmJmMTE1OGY3ZGM0ZGFfNDgy_0cdb7a59-3a78-4a60-a027-073e9f881323" continuedAt="if6bf96f269314618bf4b2c7a4c1eec2b" escape="true">Subsequent event</ix:nonNumeric></span></div><ix:continuation id="if6bf96f269314618bf4b2c7a4c1eec2b"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On October 19, 2021, Amgen completed its acquisition of Teneobio, Inc. (Teneobio), a privately held, clinical-stage biotechnology company developing a new class of biologics called heavy-chain only antibodies (HCAbs). Amgen acquired all outstanding shares in exchange for a $<ix:nonFraction unitRef="usd" contextRef="i7b7289e4de274a45a8d257b031b3ad23_D20211019-20211019" decimals="-6" format="ixt:num-dot-decimal" name="us-gaap:PaymentsToAcquireBusinessesGross" scale="6" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83My9mcmFnOjlhYzgyOGNkN2E5ODQ2NzdiMDJiZjExNThmN2RjNGRhL3RleHRyZWdpb246OWFjODI4Y2Q3YTk4NDY3N2IwMmJmMTE1OGY3ZGM0ZGFfNzY5NjU4MTM5NzcyNA_3a08b0d3-7b00-44a7-be29-94110bef1346">900</ix:nonFraction>&#160;million upfront payment, as well as future contingent milestone payments potentially worth up to an additional $<ix:nonFraction unitRef="usd" contextRef="i83f84ec51bef4ffe9c7bfc9f4c177613_I20211019" decimals="-8" format="ixt:num-dot-decimal" name="us-gaap:BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh" scale="9" id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83My9mcmFnOjlhYzgyOGNkN2E5ODQ2NzdiMDJiZjExNThmN2RjNGRhL3RleHRyZWdpb246OWFjODI4Y2Q3YTk4NDY3N2IwMmJmMTE1OGY3ZGM0ZGFfNzY5NjU4MTM5NzczOA_57620c29-635f-4eee-bdee-8640a7556438">1.6</ix:nonFraction>&#160;billion in cash upon the achievement of certain development and regulatory events.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The accounting impact of this acquisition and the results of operations for Teneobio will be included in our consolidated financial statements beginning in the fourth quarter of 2021. The initial accounting for this acquisition is incomplete, pending identification and measurement of the assets acquired and liabilities assumed.</span></div></ix:continuation><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">29</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_76"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:97.807%"><tr><td style="width:1.0%"></td><td style="width:8.018%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:89.782%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Item&#160;2.</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">MANAGEMENT&#8217;S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS</span></td></tr></table></div><div style="margin-bottom:8pt;margin-top:1pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The following Management&#8217;s Discussion and Analysis of Financial Condition and Results of Operations (MD&amp;A) is intended to assist the reader in understanding Amgen&#8217;s business. MD&amp;A is provided as a supplement to and should be read in conjunction with our Annual Report on Form 10-K for the year ended December 31, 2020, and our Quarterly Reports on Form 10-Q for the periods ended March 31, 2021 and June 30, 2021. Our results of operations discussed in MD&amp;A are presented in conformity with GAAP. Amgen operates in one business segment: human therapeutics. Therefore, our results of operations are discussed on a consolidated basis.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Forward-looking statements</span></div><div style="margin-bottom:8pt;margin-top:1pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">This report and other documents we file with the Securities and Exchange Commission (SEC) contain forward-looking statements that are based on current expectations, estimates, forecasts and projections about us, our future performance, our business, our beliefs and our management&#8217;s assumptions. In addition, we, or others on our behalf, may make forward-looking statements in press releases, written statements or our communications and discussions with investors and analysts in the normal course of business through meetings, webcasts, phone calls and conference calls. Such words as &#8220;expect,&#8221; &#8220;anticipate,&#8221; &#8220;outlook,&#8221; &#8220;could,&#8221; &#8220;target,&#8221; &#8220;project,&#8221; &#8220;intend,&#8221; &#8220;plan,&#8221; &#8220;believe,&#8221; &#8220;seek,&#8221; &#8220;estimate,&#8221; &#8220;should,&#8221; &#8220;may,&#8221; &#8220;assume&#8221; and &#8220;continue&#8221; as well as variations of such words and similar expressions are intended to identify such forward-looking statements. These statements are not guarantees of future performance and they involve certain risks, uncertainties and assumptions that are difficult to predict. We describe our respective risks, uncertainties and assumptions that could affect the outcome or results of operations in Item 1A. Risk Factors in Part II herein and in Part I, Item 1A. Risk Factors of our Annual Report on Form 10-K for the year ended December 31, 2020, and in Part II, Item 1A. Risk Factors of our Quarterly Reports on Form 10-Q for the periods ended March 31, 2021 and June 30, 2021. We have based our forward-looking statements on our management&#8217;s beliefs and assumptions based on information available to our management at the time the statements are made. We caution you that actual outcomes and results may differ materially from what is expressed, implied or forecasted by our forward-looking statements. Reference is made in particular to forward-looking statements regarding product sales, regulatory activities, clinical trial results, reimbursement, expenses, EPS, liquidity and capital resources, trends, planned dividends, stock repurchases, collaborations and effects of pandemics. Except as required under the federal securities laws and the rules and regulations of the SEC, we do not have any intention or obligation to update publicly any forward-looking statements after the distribution of this report, whether as a result of new information, future events, changes in assumptions or otherwise.</span></div><div style="margin-bottom:8pt;margin-top:1pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_79"></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">Overview</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Amgen is a biotechnology company committed to unlocking the potential of biology for patients suffering from serious illnesses. A biotechnology pioneer since 1980, Amgen has grown to be one of the world&#8217;s leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our principal products&#8212;those with the most significant annual commercial sales&#8212;are ENBREL, Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">and KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">. We also market a number of other products, including MVASI</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(bevacizumab-awwb), Nplate</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> (romiplostim), Vectibix</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> (panitumumab), KANJINTI</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(trastuzumab-anns), EPOGEN</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> (epoetin alfa), EVENITY</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(romosozumab-aqqg), BLINCYTO</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(blinatumomab), AMGEVITA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#8482; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(adalimumab), Aimovig</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(erenumab-aooe), Parsabiv</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(etelcalcetide), NEUPOGEN</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, Sensipar</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">/Mimpara</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#8482; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(cinacalcet) and LUMAKRAS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">/LUMYKRAS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#8482;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> (sotorasib).</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">COVID-19 pandemic</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">A novel strain of coronavirus (SARS-CoV-2, or severe acute respiratory syndrome coronavirus 2, causing coronavirus disease 19, or COVID-19) was declared a global pandemic by the World Health Organization on March 11, 2020. Since the onset of the pandemic in 2020, we have been closely monitoring the pandemic&#8217;s effects on our global operations. We continue to take appropriate steps to minimize risks to our employees, a significant number of whom have continued to work virtually. Employee access to company facilities has been in accordance with applicable government health and safety protocols and guidance issued in response to the COVID-19 pandemic. To date, our remote working arrangements have not significantly affected our ability to maintain critical business operations, and we have not experienced disruptions to or shortages of our supply of medicines. </span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">30</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Since the beginning of the COVID-19 pandemic, we have seen changes in demand for some of our products driven by changes in patient visits to doctors&#8217; offices that has impacted providing treatments to existing patients and reduced diagnoses in new patients. Through the third quarter, there has been gradual recovery in both patient visits and diagnoses, although overall these remain below pre-COVID-19 levels. The cumulative decrease in diagnoses over the course of the pandemic has suppressed the volume of new patients starting treatment, which we expect to continue to impact our business during the remainder of the year. We are closely monitoring the effects of emerging COVID-19 variants on patient behavior and access.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Since early 2021, global vaccination efforts have been underway to control the pandemic. However, uncertainty remains as to the length of time required for vaccination of a meaningful portion of the population and as to the efficacy of such vaccinations on the trajectory of the pandemic. Challenges to vaccination efforts, new variants and other causes of virus spread may require governments to issue additional restrictions and/or shutdowns in various geographies. As a result, we expect to see continued volatility for at least the duration of the pandemic as governments respond to current local conditions.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">With respect to our drug development activities, we are continuously monitoring COVID-19 infection rates, including changes from new variants, and working to mitigate effects on future study enrollment in our clinical trials and evaluating the impact in all countries where clinical trials occur. We remain focused on supporting our active clinical sites in their providing care for patients and in our providing investigational drug supply.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Despite the ongoing pandemic and business impacts noted above, we believe that existing funds, cash generated from operations and existing sources of and access to financing are adequate to satisfy our needs for working capital, capital expenditures and debt service requirements as well as to engage in the capital-return and other business initiatives that we plan to pursue. For a discussion of the risks the COVID-19 pandemic presents to our results, see Risk Factors in Item 1A. Risk Factors in Part II herein and in Part I, Item 1A. Risk Factors of our Annual Report on Form 10-K for the year ended December 31, 2020, and in Part II, Item 1A. Risk Factors of our Quarterly Reports on Form 10-Q for the periods ended March 31, 2021 and June 30, 2021.</span></div><div style="text-align:justify;text-indent:22.5pt"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_82"></div><div style="text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">Significant developments</span></div><div style="text-align:justify"><span><br/></span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Following is a summary of selected significant developments affecting our business that occurred since the filing of our Quarterly Report on Form 10-Q for the period ended June 30, 2021. For additional developments or for a more comprehensive discussion of certain developments discussed below, see our Annual Report on Form 10-K for the year ended December 31, 2020, and our Quarterly Reports on Form 10-Q for the periods ended March 31, 2021 and June 30, 2021.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Business Development</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Acquisition</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Teneobio</span></div><div style="margin-bottom:8pt;padding-left:49.5pt;text-align:justify;text-indent:-18pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">&#8226;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:14.5pt">On October 19, 2021, Amgen completed its acquisition of Teneobio, a privately held, clinical-stage biotechnology company, for $900 million as well as future contingent milestone payments potentially worth up to an additional $1.6 billion upon the achievement of certain development and regulatory events.</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_85"></div><div style="text-align:justify"><span><br/></span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">31</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">Selected financial information</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The following is an overview of our results of operations (in millions, except percentages and per-share data):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:36.765%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.087%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.094%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Product sales</span></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S.</span></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,558&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,618&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,835&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13,325&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(4)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">ROW</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,762&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,486&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">19&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5,191&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,581&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 19pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total product sales</span></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,320&#160;</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,104&#160;</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18,026&#160;</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">17,906&#160;</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other revenues</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">386&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">319&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">21&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,107&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">884&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">25&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 19pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total revenues</span></td><td style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,706&#160;</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,423&#160;</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">19,133&#160;</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18,790&#160;</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Operating expenses</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,328&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,970&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13,798&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">11,659&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Operating income</span></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,378&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,453&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(3)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5,335&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">7,131&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(25)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,884&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,021&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(7)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,994&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5,649&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(29)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Diluted EPS</span></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.31&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.43&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(3)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.93&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9.54&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(27)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Diluted shares</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">570&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">589&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(3)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">576&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">592&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(3)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In the following discussion of changes in product sales, any reference to unit demand growth or decline refers to changes in the purchases of our products by healthcare providers (such as physicians or their clinics), dialysis centers, hospitals and pharmacies. In addition, any reference to increases or decreases in inventory refers to changes in inventory held by wholesaler customers and end users (such as pharmacies).</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Total product sales increased for the three months ended September 30, 2021, primarily driven by higher unit demand for certain brands, including Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> and EVENITY</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, and by favorable changes to estimated sales deductions, partially offset by declines in the net selling prices of certain products. Total product sales increased for the nine months ended September 30, 2021, primarily driven by higher unit demand for certain brands, including Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> and MVASI</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, partially offset by declines in the net selling prices of certain products. We expect the trend of net selling price declines to continue to affect our business. Going forward, we expect that net selling price declines will be driven by ENBREL, Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">and some of our biosimilar products. There was gradual recovery through the third quarter of 2021 in patients resuming their treatments and in new patient starts, although overall, both numbers remain below pre-COVID-19 levels.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Throughout the pandemic, we experienced changes in demand for some of our products. The pandemic has interrupted many physician&#8211;patient interactions, which has led to delays in diagnoses and treatments, with varying degrees of impact across our portfolio. In general, declines in the sales of our products that were impacted by the dynamics of the pandemic were most significant in the early months of the pandemic with product demand beginning to show some recovery in late 2020. Through the third quarter of 2021, demand continued to gradually recover from the impact of the pandemic and there was improvement in patient visits and diagnoses. Healthcare provider activity also stabilized during the third quarter after having improved during the first half of 2021. However, the cumulative decrease in diagnoses over the course of the pandemic has suppressed the volume of new patients starting treatment, which we expect to continue to impact our business for the remainder of the year. Given the unpredictable nature of the pandemic, we expect there could be ongoing intermittent disruptions in physician&#8211;patient interactions, and as a result, we continue to expect quarter-to-quarter variability. In addition, other changes in the healthcare ecosystem have the potential to introduce variability into product sales trends. For example, we expect changes in U.S. employment to lead to changes to the insured population. Growth in numbers of Medicaid enrollees and uninsured individuals may have a negative impact on product demand and sales. Overall, uncertainty remains around the timing and magnitude of our sales during the COVID-19 pandemic. See Risk Factors in Part II, Item 1A. of this Form 10-Q and Part I, Item 1A. Risk Factors of our Annual Report on Form 10-K for the year ended December 31, 2020, and in Part II, Item 1A. Risk Factors of our Quarterly Reports on Form 10-Q for the periods ended March 31, 2021 and June 30, 2021.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Other revenues increased for the three and nine months ended September 30, 2021, primarily driven by the sale of COVID-19 antibody material.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Operating expenses increased for the three months ended September 30, 2021, primarily driven by an upfront payment associated with the KKC licensing agreement. Operating expenses increased for the nine months ended September 30, 2021, primarily driven by IPR&amp;D expense related to the bemarituzumab program acquired as part of the Five Prime acquisition and by an upfront payment associated with the KKC licensing agreement.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">32</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Although changes in foreign currency exchange rates result in increases or decreases in our reported international product sales, the benefit or detriment that such movements have on our international product sales is partially offset by corresponding increases or decreases in our international operating expenses and our related foreign currency hedging activities. Our hedging activities seek to offset the impacts, both positive and negative, that foreign currency exchange rate changes may have on our net income by hedging our net foreign currency exposure, primarily with respect to product sales denominated in euros. The net impact from changes in foreign currency exchange rates was not material for the three and nine months ended September 30, 2021 and 2020.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_88"></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">Results of operations</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Product sales</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Worldwide product sales were as follows (dollar amounts in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:36.765%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.087%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.094%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">ENBREL</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,289&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,325&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(3)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,357&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,724&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(10)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">803&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">701&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,375&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,014&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">609&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">538&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,619&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,578&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;&#160;</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">517&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">481&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">7&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,473&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,397&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">415&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">555&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(25)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,383&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,757&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(21)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">396&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">384&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,118&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,193&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(6)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">272&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">205&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">844&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">634&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">293&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">260&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">824&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">793&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other products</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,726&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,655&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5,033&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,816&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total product sales</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,320&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,104&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18,026&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">17,906&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Future sales of our products will depend in part on the factors discussed below and in the following sections of this report: (i) Part I, Item 2. Management&#8217;s Discussion and Analysis of Financial Condition and Results of Operations&#8212;Overview and Selected Financial Information; and (ii) Part II, Item 1A. Risk Factors; and in the following sections of our Annual Report on Form 10-K for the year ended December 31, 2020: (i) Item 1. Business&#8212;Marketing, Distribution and Selected Marketed Products, (ii) Item 1A. Risk Factors and (iii) Item&#160;7. Management&#8217;s Discussion and Analysis of Financial Condition and Results of Operations&#8212;Overview, and Results of Operations&#8212;Product Sales, as well as in our Quarterly Reports on Form 10-Q for the periods ended March 31, 2021 and June 30, 2021, in (i) Part I, Item 2. Management&#8217;s Discussion and Analysis of Financial Condition and Results of Operations&#8212;Results of Operations&#8212;Product Sales; and (ii) Part II, Item 1A. Risk Factors.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">ENBREL</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Total ENBREL sales by geographic region were as follows (dollar amounts in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:36.765%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.087%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.094%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">ENBREL &#8212; U.S.</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,263&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,289&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(2)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,270&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,619&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(10)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">ENBREL &#8212; Canada</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">26&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">36&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(28)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">87&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">105&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(17)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total ENBREL</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,289&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,325&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(3)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,357&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,724&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(10)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The decrease in ENBREL sales for the three months ended September 30, 2021, was driven by a decline in unit demand, unfavorable changes in inventory and lower net selling price, partially offset by favorable changes to estimated sales deductions. The decrease in ENBREL for the nine months ended September 30, 2021, was driven by declines in net selling price and unit demand. For the remainder of 2021, we expect the trend of net selling price declines to continue compared with the prior year.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">33</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We are involved in patent litigation with a company seeking to market its FDA-approved biosimilar version of ENBREL. See Note 19, Contingencies and commitments, to the consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2020, and Note 13, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended June 30, 2021. Companies with approved biosimilar versions of ENBREL may seek to enter the U.S. market if we are not ultimately successful in our litigations, or even earlier. Other companies are also developing proposed biosimilar versions of ENBREL.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Total Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> sales by geographic region were as follows (dollar amounts in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:36.765%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.087%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.094%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;&#8212;&#160;U.S.</span></div></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">530&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">478&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">11&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,569&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,341&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">17&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;&#8212;&#160;ROW</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">273&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">223&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">22&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">806&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">673&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">20&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:13.5pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">803&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">701&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,375&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,014&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The increase in global Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">sales for the three and nine months ended September 30, 2021, was primarily driven by higher unit demand.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Total Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> sales by geographic region were as follows (dollar amounts in millions):</span></div><div style="margin-bottom:8pt;text-align:justify"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:37.204%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.087%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:6.655%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;&#8212;&#160;U.S.</span></div></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">495&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">439&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,284&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,280&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;&#8212;&#160;ROW</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">114&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">99&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">335&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">298&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:6.75pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">609&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">538&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,619&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,578&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The increase in global Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> sales for the three months ended September 30, 2021, was primarily driven by higher unit demand and favorable changes to estimated sales deductions, partially offset by lower net selling price. The increase in global Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> sales for the nine months ended September 30, 2021, was driven by higher unit demand, partially offset by lower net selling price. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">For a discussion of litigation related to Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, see Note 19, Contingencies and commitments, to the consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2020; Notes 12 and 13, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Reports on Form 10-Q for the periods ended March 31, 2021 and June 30, 2021, respectively; and Note 14, Contingencies and commitments, to the condensed consolidated financial statements in this Quarterly Report.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Total XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> sales by geographic region were as follows (dollar amounts in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:36.765%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.087%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.094%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;&#8212;&#160;U.S.</span></div></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">372&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">363&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,061&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,036&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;&#8212;&#160;ROW</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">145&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">118&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">23&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">412&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">361&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:6.75pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">517&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">481&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">7&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,473&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,397&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The increase in global XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">sales for the three and nine months ended September 30, 2021, was driven by higher unit demand, partially offset by lower net selling price.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">34</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Total Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">sales by geographic region were as follows (dollar amounts in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:36.765%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.087%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.094%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; U.S.</span></div></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">360&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">484&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(26)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,215&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,538&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(21)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; ROW</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">55&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">71&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(23)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">168&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">219&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(23)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:13.5pt;text-indent:-4.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">415&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">555&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(25)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,383&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,757&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(21)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:115%">The decrease in global Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:115%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:115%">sales for the three months ended September 30, 2021, was primarily driven by the impact of biosimilar competition on net selling price and unit demand. The decrease in global Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:115%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:115%">sales for the nine months ended September 30, 2021, was driven by the impact of biosimilar competition on net selling price and unit demand, partially offset by favorable changes to estimated sales deductions. Increased competition in the United States and Europe as a result of biosimilar versions of Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:115%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:115%"> has had and will continue to have a significant adverse impact on brand sales, including additional net price erosion and lower unit demand. We also expect other biosimilar versions to be approved in the future. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:115%">For a discussion of ongoing patent litigations related to biosimilars, see Note 19, Contingencies and commitments, to the consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2020; Notes 12 and 13, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Reports on Form 10-Q for the periods ended March 31, 2021 and June 30, 2021, respectively; and Note 14, Contingencies and commitments, to the condensed consolidated financial statements in this Quarterly Report.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Total Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> sales by geographic region were as follows (dollar amounts in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:36.765%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.087%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.094%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> &#8212; U.S.</span></div></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">149&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">158&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(6)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">409&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">489&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(16)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> &#8212; ROW</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">247&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">226&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">709&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">704&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:6.75pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">396&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">384&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,118&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,193&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(6)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The increase in global Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> sales for the three months ended September 30, 2021, was driven by higher unit demand and favorable changes to estimated sales deductions, partially offset by lower net selling price due to competition. The decrease in global Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> sales for the nine months ended September 30, 2021, was primarily driven by lower net selling price due to competition.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> continues to face competition from a long-acting erythropoiesis-stimulating agent (ESA) and</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:5.85pt;font-weight:400;line-height:120%;position:relative;top:-3.15pt;vertical-align:baseline"> </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">also faces competition from a biosimilar version of EPOGEN</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, which will continue to impact sales in the future.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Total Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> sales by geographic region were as follows (dollar amounts in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:36.765%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.087%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.094%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> &#8212; U.S.</span></div></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">139&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">92&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">51&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">421&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">331&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">27&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> &#8212; ROW</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">133&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">113&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">423&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">303&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">40&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:6.75pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">272&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">205&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">844&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">634&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The increase in global Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> sales for the three and nine months ended September 30, 2021, was primarily driven by higher unit demand, partially offset by lower net selling price.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">35</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">For a discussion of ongoing litigation related to Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, see Note 19, Contingencies and commitments, to the consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2020; Notes 12 and 13, Contingencies and commitments, to the condensed consolidated financial statements for the periods ended March 31, 2021 and June 30, 2021, respectively; and Note 14, Contingencies and commitments, to the condensed consolidated financial statements in this Quarterly Report.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Total KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> sales by geographic region were as follows (dollar amounts in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:36.765%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.087%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.094%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> &#8212; U.S.</span></div></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">198&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">173&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">547&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">527&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> &#8212; ROW</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">95&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">87&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">277&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">266&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:6.75pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">293&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">260&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">824&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">793&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The increase in global KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">sales for the three and nine months ended September 30, 2021, was primarily driven by higher unit demand. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We are engaged in litigation with two companies that are challenging certain of our patents related to KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">and that are seeking to market generic carfilzomib products.&#160;Separately, we have entered into confidential settlement agreements with other companies developing generic carfilzomib products, and the court has entered consent judgments enjoining those companies from infringing certain of our patents, subject to terms of the confidential settlement agreements.&#160;See Note 19, Contingencies and commitments, to the consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2020; and Notes 12 and 13, Contingencies and commitments, to the condensed consolidated financial statements for the periods ended March 31, 2021 and June 30, 2021, respectively. The FDA has reported that it has granted tentative or final approval of ANDAs for generic carfilzomib products filed by a number of companies. The date of approval of those ANDAs for generic carfilzomib products is governed by the Hatch-Waxman Act and any applicable settlement agreements between the parties.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">36</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Other products</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Other product sales by geographic region were as follows (dollar amounts in millions):</span></div><div style="text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:36.765%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.087%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.094%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">MVASI</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; U.S.</span></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">187&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">185&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">617&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">442&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">40&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">MVASI</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; ROW</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">87&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">46&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">89&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">245&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">76&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">*</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Nplate</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; U.S.</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">156&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">118&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">404&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">352&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Nplate</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; ROW</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">117&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">94&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">24&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">341&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">271&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">26&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Vectibix</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; U.S.</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">84&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">90&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(7)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">255&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">249&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Vectibix</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; ROW</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">116&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">103&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">375&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">341&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">KANJINTI</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; U.S.</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">92&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">149&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(38)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">354&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">346&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">KANJINTI</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; ROW</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">24&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">79&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">63&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">25&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">EPOGEN</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; U.S.</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">138&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">149&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(7)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">393&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">465&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(15)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">EVENITY</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> &#8212; U.S.</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">94&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">54&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">74&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">230&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">131&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">76&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">EVENITY</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; ROW</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">55&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">*</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">157&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">129&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">22&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">BLINCYTO</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> &#8212; U.S.</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">74&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">54&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">37&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">201&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">167&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">20&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">BLINCYTO</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> &#8212; ROW</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">51&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">35&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">46&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">139&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">109&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">28&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">AMGEVITA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#8482; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; ROW</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">111&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">80&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">39&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">324&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">228&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">42&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Aimovig</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> &#8212; U.S.</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">77&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">105&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(27)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">225&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">274&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(18)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Aimovig</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> &#8212; ROW</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">NM</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">NM</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Parsabiv</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> &#8212; U.S.</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">24&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">156&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(85)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">107&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">462&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(77)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Parsabiv</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> &#8212; ROW</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">37&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">27&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">37&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">104&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">82&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">27&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">NEUPOGEN</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; U.S.</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">44&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(27)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">86&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">117&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(26)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">NEUPOGEN</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; ROW</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">20&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">21&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(5)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">51&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">62&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(18)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Sensipar</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> &#8212; U.S.</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">7&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(100)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">81&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(95)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Sensipar</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">/Mimpara</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#8482; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; ROW</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">19&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(41)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">62&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">162&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(62)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">LUMAKRAS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; U.S.</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">NM</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">42&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">NM</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">LUMYKRAS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#8482; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212; ROW</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">NM</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">NM</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other &#8212; U.S.</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">61&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">31&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">97&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">141&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">78&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">81&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other &#8212; ROW</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">52&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(38)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">92&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">129&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(29)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total other products</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,726&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,655&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5,033&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,816&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total U.S. &#8212; other products</span></td><td style="background-color:#ffffff;border-top:3pt double #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:3pt double #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,052&#160;</span></td><td style="background-color:#ffffff;border-top:3pt double #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:3pt double #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:3pt double #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,142&#160;</span></td><td style="background-color:#ffffff;border-top:3pt double #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(8)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:3pt double #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:3pt double #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,059&#160;</span></td><td style="background-color:#ffffff;border-top:3pt double #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-top:3pt double #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:3pt double #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,164&#160;</span></td><td style="background-color:#ffffff;border-top:3pt double #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(3)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total ROW &#8212; other products</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">674&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">513&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">31&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,974&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,652&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">19&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total other products</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,726&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,655&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5,033&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,816&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">___________</span></div><div style="margin-bottom:3pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:120%">NM - Not meaningful</span></div><div style="text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:120%">* - Change in excess of 100%</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">37</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_91"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Operating expenses</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Operating expenses were as follows (dollar amounts in millions):</span></div><div style="text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:36.911%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.384%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.087%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.426%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.094%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Change</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Operating expenses:</span></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cost of sales</span></div></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,609&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,561&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,736&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,562&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">% of product sales</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">25.5&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">25.6&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">26.3&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">25.5&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">% of total revenues</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">24.0&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">24.3&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">24.8&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">24.3&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Research and development</span></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,422&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,062&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">34&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,471&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,978&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">17&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">% of product sales</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">22.5&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">17.4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">19.3&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">16.6&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">% of total revenues</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">21.2&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">16.5&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18.1&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15.8&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Acquired in-process research and development</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,505&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">NM</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">% of product sales</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">8.3&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">% of total revenues</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">7.9&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Selling, general and administrative</span></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,305&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,346&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(3)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,943&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,957&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">% of product sales</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">20.6&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">22.1&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">21.9&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">22.1&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">% of total revenues</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">19.5&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">21.0&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">20.6&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">21.1&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(8)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">*</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">143&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">162&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(12)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">___________</span></div><div style="margin-bottom:3pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:120%">NM - Not meaningful</span></div><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:120%">* - Change in excess of 100%</span></div><div><span><br/></span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Cost of sales</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Cost of sales decreased to 24.0% of total revenues for the three months ended September 30, 2021, primarily driven by lower amortization expense from acquisition-related assets, offset by unfavorable product mix. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Cost of sales increased to 24.8% of total revenues for the nine months ended September 30, 2021, primarily driven by unfavorable product mix, partially offset by lower amortization expense from acquisition-related assets.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Research and development</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The increase in R&amp;D expense for the three months ended September 30, 2021, was driven by a licensing-related upfront payment to KKC, partially offset by lower late-stage support for existing programs.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The increase in R&amp;D expense for the nine months ended September 30, 2021, was primarily driven by a licensing-related upfront payment to KKC and higher research and early pipeline spend, partially offset by lower late-stage support for existing programs.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:115%">Acquired in-process research and development</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Acquired IPR&amp;D expense for the nine months ended September 30, 2021, is related to the bemarituzumab program acquired as part of the Five Prime acquisition.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Selling, general and administrative</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The decrease in Selling, general and administrative (SG&amp;A) expense for the three months ended September 30, 2021, was primarily driven by lower spend in general and administrative activities.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The decrease in SG&amp;A expense for the nine months ended September 30, 2021, was primarily driven by lower spend in general and administrative activities and favorable adjustments to estimated U.S. healthcare reform federal excise fees, partially offset by higher marketed-product support and investment in new launches.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">38</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Other</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Other operating expenses for the three months ended September 30, 2021, consisted primarily of changes in the fair values of contingent consideration liabilities. Other operating expenses for the nine months ended September 30, 2021, consisted primarily of expenses related to cost savings initiatives.</span></div><div style="text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Other operating expenses for the nine months ended September 30, 2020, consisted of legal settlement expenses.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_94"></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Nonoperating expense/income and income taxes</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Nonoperating expense/income and income taxes were as follows (dollar amounts in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:45.829%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.619%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.619%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.619%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.624%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest expense, net</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(296)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(302)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(862)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(944)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income, net</span></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">73&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">55&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">97&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">69&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Provision for income taxes</span></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">271&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">185&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">576&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">607&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Effective tax rate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12.6&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">8.4&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12.6&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9.7&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Interest expense, net</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The decrease in Interest expense, net, for the three months ended September 30, 2021, was primarily due to lower LIBOR rates in the current year period on debt for which we effectively pay a variable rate of interest through the use of interest rate swaps, partially offset by higher overall debt outstanding in the current year period.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The decrease in Interest expense, net, for the nine months ended September 30, 2021, was primarily due to net costs associated with the early retirement of debt in the first quarter of the prior year and lower LIBOR rates in the current year period on debt for which we effectively pay a variable rate of interest through the use of interest rate swaps, partially offset by higher overall debt outstanding in the current year period.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Other income, net</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The increase in Other income, net, for the three and nine months ended September 30, 2021, was primarily due to net gains recognized on our strategic equity investments, partially offset by higher losses in connection with our BeiGene investment.</span></div><div id="i0b2dd96150e340208a57faec23ec2da5_97"></div><div style="margin-bottom:8pt;margin-top:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Income taxes</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The increase in our effective tax rate for the three and nine months ended September 30, 2021, was primarily due to the non-deductible IPR&amp;D expense arising from the acquisition of Five Prime and prior year favorable items partially offset by a change in earnings mix. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The Administration and Congress are considering significant changes to existing tax law, including an increase in the corporate tax rate and the tax rate on foreign earnings. These changes could substantially increase U.S. taxation of our operations both in and outside the United States, including the U.S. territory of Puerto Rico. In addition, the Organisation for Economic Co-operation and Development (OECD) recently reached agreement to align countries on a minimum corporate tax rate and an expansion of the taxing rights of market countries. If enacted, this agreement could result in tax increases in both the United States and foreign jurisdictions. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In 2017, we received an RAR and a modified RAR from the IRS for the years 2010, 2011 and 2012 proposing significant adjustments that primarily relate to the allocation of profits between certain of our entities in the United States and the U.S. territory of Puerto Rico. We disagreed with the proposed adjustments and calculations and pursued a resolution with the IRS administrative appeals office. As previously reported, we were unable to reach resolution with the IRS appeals office. In July 2021, we filed a petition in the U.S. Tax Court to contest two duplicate Notices for 2010, 2011 and 2012 that we received in May and July 2021. The duplicate Notices seek to increase our U.S. taxable income by an amount that would result in additional federal tax of approximately $3.6 billion, plus interest. Any additional tax that could be imposed would be reduced by up to approximately $900 million of repatriation tax previously accrued on our foreign earnings. In any event, we firmly believe that the IRS&#8217;s positions in the Notices are without merit, and we will vigorously contest the Notices through the judicial process. </span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">39</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In addition, in 2020, we received an RAR and a modified RAR from the IRS for the years 2013, 2014 and 2015 also proposing significant adjustments that primarily relate to the allocation of profits between certain of our entities in the United States and the U.S. territory of Puerto Rico, similar to those proposed for the years 2010, 2011 and 2012. We disagree with the proposed adjustments and calculations and have been pursuing resolution with the IRS administrative appeals office. As a consequence of the Tax Court litigation for the 2010-2012 period, the IRS administrative appeals office recently informed us that it does not plan to engage in discussions at this time regarding the allocation of profits between our entities in the United States and the U.S. territory of Puerto Rico for the 2013-2015 period. We are currently under examination by the IRS for the years 2016, 2017 and 2018. We are also currently under examination by a number of other state and foreign tax jurisdictions. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Final resolution of these complex matters is not likely within the next 12 months. We believe our accrual for income tax liabilities is appropriate based on past experience, interpretations of tax law, application of the tax law to our facts and judgments about potential actions by tax authorities; however, due to the complexity of the provision for income taxes and uncertain resolution of these matters, the ultimate outcome of any tax matters may result in payments substantially greater than amounts accrued as noted above and could have a material adverse impact on our condensed consolidated financial statements.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">See Note 4, Income taxes, to the condensed consolidated financial statements for further discussion.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_100"></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">Financial condition, liquidity and capital resources</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Selected financial data were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:65.128%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.420%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.422%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash, cash equivalents and marketable securities</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,921&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10,647&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total assets</span></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">64,993&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">62,948&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Current portion of long-term debt</span></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,288&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">91&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Long-term debt</span></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33,291&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32,895&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Stockholders&#8217; equity</span></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">8,217&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9,409&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Cash, cash equivalents and marketable securities</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our balance of cash, cash equivalents and marketable securities was $12.9 billion at September 30, 2021. The primary objective of our investment portfolio is to maintain safety of principal, prudent levels of liquidity and acceptable levels of risk. Our investment policy limits interest-bearing security investments to certain types of debt and money market instruments issued by institutions with investment-grade credit ratings, and it places restrictions on maturities and concentration by asset class and issuer.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Capital allocation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We intend to continue to invest in our business while returning capital to stockholders through the payment of cash dividends and stock repurchases, thereby reflecting our confidence in the future cash flows of our business and our desire to optimize our cost of capital. The timing and amount of future dividends and stock repurchases will vary based on a number of factors, including future capital requirements for strategic transactions, availability of financing on acceptable terms, debt service requirements, our credit rating, changes to applicable tax laws or corporate laws, changes to our business model and periodic determination by our Board of Directors that cash dividends and/or stock repurchases are in the best interests of stockholders and are in compliance with applicable laws and the Company&#8217;s agreements. In addition, the timing and amount of stock repurchases may also be affected by our overall level of cash, stock price and blackout periods, during which we are restricted from repurchasing stock.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In July 2021, March 2021 and December 2020, the Board of Directors declared a quarterly cash dividend of $1.76 per share of common stock, which were paid on September 8, 2021, June 8, 2021 and March 8, 2021, respectively, an increase of 10% over the quarterly cash dividend paid in each quarter in 2020. In October 2021, the Board of Directors declared a quarterly dividend of $1.76 per share, which will be paid on December 8, 2021.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We also returned capital to stockholders through our stock repurchase program. During the nine months ended September 30, 2021, we executed trades to repurchase $3.5 billion of common stock. As of September 30, 2021, $2.9 billion of authorization remained available under our stock repurchase program. In October 2021, the Board of Directors increased the amount authorized under our stock repurchase program by an additional $4.5 billion.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">40</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">As a result of stock repurchases and quarterly dividend payments, we have an accumulated deficit as of September 30, 2021 and December 31, 2020. Our accumulated deficit is not anticipated to affect our future ability to operate, repurchase stock, pay dividends or repay our debt given our continuing profitability and strong financial position.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We believe that existing funds, cash generated from operations and existing sources of and access to financing are adequate to satisfy our needs for working capital, to meet capital expenditure and debt service requirements, to fund our plans to pay dividends and repurchase stock and to fulfill other business initiatives we expect to strategically pursue, including acquisitions and licensing activities. We anticipate that our liquidity needs can be met through a variety of sources, including cash provided by operating activities, sales of marketable securities, equity markets and borrowings (including commercial paper and/or syndicated credit facilities and access to other domestic and foreign debt markets). See our Annual Report on Form&#160;10-K for the year ended December 31, 2020, Part I, Item&#160;1A. Risk Factors&#8212;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Global economic conditions may negatively affect us and may magnify certain risks that affect our business</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Certain of our financing arrangements contain nonfinancial covenants. In addition, our revolving credit agreement includes a financial covenant that requires us to maintain a specified minimum interest coverage ratio of (i) the sum of consolidated net income, interest expense, provision for income taxes, depreciation expense, amortization expense, unusual or nonrecurring charges and other noncash items (Consolidated EBITDA) to (ii) Consolidated Interest Expense, each as defined and described in the credit agreement. We were in compliance with all applicable covenants under these arrangements as of September 30, 2021.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Cash flows</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our summarized cash flow activity was as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:65.128%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.420%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:15.422%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net cash provided by operating activities</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,453&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">8,344&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net cash provided by (used in) investing activities</span></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">963&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(4,017)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net cash used in financing activities</span></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1,713)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1,277)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Operating</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Cash provided by operating activities is expected to be our primary recurring source of funds. Cash provided by operating activities during the nine months ended September 30, 2021, decreased primarily due to (i) the monetization of interest rate swaps in the prior year, (ii) a difference in the timing of payments to tax authorities and sales deductions paid to customers, (iii) lower Net income, after adjustments for noncash items and (iv) the timing of collections from customers.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Investing</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Cash provided by investing activities during the nine months ended September 30, 2021, was primarily due to net cash inflows related to marketable securities of $3.4 billion, partially offset by the acquisition of Five Prime for $1.6 billion, net of cash acquired, and capital expenditures of $593 million. Cash used in investing activities during the nine months ended September 30, 2020, was due to our $3.2 billion of equity investments, primarily BeiGene, capital expenditures of $435 million and net cash outflows related to marketable securities of $394 million. We currently estimate 2021 spending on capital projects to be approximately $900 million.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Financing</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Cash used in financing activities during the nine months ended September 30, 2021, was primarily due to payments to repurchase our common stock of $3.5 billion and the payment of dividends of $3.0 billion, partially offset by proceeds from the issuance of debt of $4.9 billion. Cash used in financing activities during the nine months ended September 30, 2020, was primarily due to the payment of dividends of $2.8 billion and payments to repurchase our common stock of $2.3 billion, partially offset by proceeds from the issuance of debt, net of repayments, of $3.9 billion. See Note 10, Financing arrangements, and Note 11, Stockholders&#8217; equity, to the condensed consolidated financial statements for further discussion. </span></div><div id="i0b2dd96150e340208a57faec23ec2da5_103"></div><div style="text-align:justify"><span><br/></span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">41</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">Critical accounting policies</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The preparation of our condensed consolidated financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the amounts reported in the financial statements and the notes to the financial statements. Some of those judgments can be subjective and complex, and therefore actual results could differ materially from those estimates under different assumptions or conditions. A summary of our critical accounting policies is presented in Part II, Item&#160;7. Management&#8217;s Discussion and Analysis of Financial Condition and Results of Operations, of our Annual Report on Form 10-K for the year ended December 31, 2020.</span></div><div id="i0b2dd96150e340208a57faec23ec2da5_106"></div><div style="margin-top:15pt;text-align:justify"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.853%"><tr><td style="width:1.0%"></td><td style="width:9.880%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:87.920%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Item&#160;3.</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Information about our market risk is disclosed in Part II, Item 7A. Quantitative and Qualitative Disclosures About Market Risk, of our Annual Report on Form 10-K for the year ended December 31, 2020, and is incorporated herein by reference. Except as discussed below, there were no material changes during the nine months ended September 30, 2021, to the information provided in Part II, Item 7A. Quantitative and Qualitative Disclosures About Market Risk, of our Annual Report on Form 10-K for the year ended December 31, 2020.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Interest rate sensitive financial instruments</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">To achieve a desired mix of fixed and floating interest rate debt, we entered into additional interest rate swap contracts with an aggregate notional amount of $1.5 billion during the three months ended June 30, 2021. As of September 30, 2021, an aggregate notional amount of $7.4 billion of interest rate swap contracts was outstanding. These interest rate swap contracts effectively converted a fixed-interest-rate coupon to a floating-rate LIBOR-based coupon over the life of the respective notes. A hypothetical 100-basis-point increase in interest rates relative to interest rates at September 30, 2021, would have resulted in a reduction in fair value of approximately $370 million on our interest rate swap contracts on that date. The analysis of the interest rate swap contracts does not consider the impact that hypothetical changes in interest rates would have on the related fair value of debt that these interest-rate-sensitive instruments were designed to offset.</span></div><div id="i0b2dd96150e340208a57faec23ec2da5_109"></div><div style="text-align:justify"><span><br/></span></div><div style="text-align:justify"><span><br/></span></div><div style="text-align:justify"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.853%"><tr><td style="width:1.0%"></td><td style="width:9.880%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:87.920%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Item&#160;4.</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">CONTROLS AND PROCEDURES</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We maintain &#8220;disclosure controls and procedures,&#8221; as such term is defined under the Securities Exchange Act Rule 13a-15(e) that are designed to ensure that information required to be disclosed in Amgen&#8217;s Exchange Act reports gets recorded, processed, summarized and reported within the time periods specified in the SEC&#8217;s rules and forms and that such information gets accumulated and communicated to Amgen&#8217;s management, including its Chief Executive Officer and Chief Financial Officer, as appropriate, to facilitate timely decisions regarding required disclosures. In designing and evaluating the disclosure controls and procedures, Amgen&#8217;s management recognized that any controls and procedures, no matter how well designed and operated, can provide only reasonable assurance of achieving the desired control objectives, and in reaching a reasonable level of assurance, Amgen&#8217;s management necessarily was required to apply its judgment in evaluating the cost&#8211;benefit relationship of possible controls and procedures. We carried out an evaluation under the supervision and with the participation of our management, including Amgen&#8217;s Chief Executive Officer and Chief Financial Officer, of the effectiveness of the design and operation of Amgen&#8217;s disclosure controls and procedures. Based on their evaluation and subject to the foregoing, the Chief Executive Officer and Chief Financial Officer concluded that our disclosure controls and procedures were effective as of September 30, 2021.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Management determined that as of September 30, 2021, no changes in our internal control over financial reporting had occurred during the fiscal quarter then ended that materially affected or are reasonably likely to materially affect our internal control over financial reporting.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">42</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_112"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">PART II &#8212; OTHER INFORMATION</span></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_115"></div><div style="margin-bottom:8pt;text-align:justify"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.853%"><tr><td style="width:1.0%"></td><td style="width:9.880%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:87.920%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Item&#160;1.</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">LEGAL PROCEEDINGS</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">See Notes 12, 13 and 14, Contingencies and commitments, to the condensed consolidated financial statements included in our Quarterly Reports on Form 10-Q for the periods ended March 31, 2021, June 30, 2021 and September 30, 2021, respectively, for discussions that are limited to certain recent developments concerning our legal proceedings. Those discussions should be read in conjunction with Note 19, Contingencies and commitments, to the consolidated financial statements in Part IV of our Annual Report on Form 10-K for the year ended December 31, 2020.</span></div><div style="text-align:justify;text-indent:22.5pt"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_118"></div><div style="margin-bottom:8pt;text-align:justify"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.853%"><tr><td style="width:1.0%"></td><td style="width:9.880%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:87.920%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Item&#160;1A.</span></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">RISK FACTORS</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">This report and other documents we file with the SEC contain forward-looking statements that are based on current expectations, estimates, forecasts and projections about us, our future performance, our business, our beliefs and our management&#8217;s assumptions. These statements are not guarantees of future performance, and they involve certain risks, uncertainties and assumptions that are difficult to predict. You should carefully consider the risks and uncertainties our business faces. The risks described below are not the only ones we face. Our business is also subject to the risks that affect many other companies, such as employment relations, general economic conditions, geopolitical events and international operations. Further, additional risks not currently known to us or that we currently believe are immaterial may in the future materially and adversely affect our business, operations, liquidity and stock price.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Below we provide in supplemental form the material changes to our risk factors that occurred during the past quarter. Our risk factors disclosed in Part I, Item 1A, of our Annual Report, on Form 10-K for the year ended December 31, 2020, provide additional disclosure for these supplemental risks and are incorporated herein by reference.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">RISKS RELATED TO ECONOMIC CONDITIONS AND OPERATING A GLOBAL BUSINESS, INCLUDING DURING THE COVID-19 PANDEMIC</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#212529;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">The COVID-19 pandemic, and the effort to mitigate the spread of the disease, have had, and are expected to continue to have, an adverse effect, and may have a material adverse effect, on our clinical trials, operations, manufacturing, supply chains, distribution systems, product development, product sales, business and results of operations.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The novel coronavirus identified in late 2019, SARS-CoV-2, which causes the disease known as COVID-19, is an ongoing global pandemic that has resulted in public and governmental efforts to contain or slow the spread of the disease, including widespread shelter-in-place orders, social distancing interventions, quarantines, travel restrictions and various forms of operational shutdowns. The COVID-19 pandemic and the resulting measures implemented in response to the pandemic are adversely affecting, and are expected to continue to adversely affect, our business (including our R&amp;D, clinical trials, operations, manufacturing, supply chains, distribution systems, product development and sales activities), the business activities of our suppliers, customers, third-party payers and our patients. See our Annual Report on Form 10-K for the year ended December 31, 2020, Part I, Item 1A. Risk Factors&#8212;</span><span style="background-color:#ffffff;color:#212529;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">The COVID-19 pandemic, and the public and governmental effort to mitigate against the spread of the disease, have had, and are expected to continue to have, an adverse effect, and may have a material adverse effect, on our clinical trials, operations, supply chains, distribution systems, product development, product sales, business and results of operations</span><span style="background-color:#ffffff;color:#212529;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">;</span><span style="color:#212529;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"> </span><span style="background-color:#ffffff;color:#212529;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">see also </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Our current products and products in development cannot be sold without regulatory approval</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"> </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">and see also </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">We must conduct clinical trials in humans before we commercialize and sell any of our product candidates or existing products for new indications</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">. Due to the pandemic and these measures and their effects, we have experienced, and expect to continue to experience, unpredictable reductions in demand for certain of our products, exacerbated by COVID-19 surges resulting in repeated shutdowns and/or disruptions in certain geographies.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Federal, state and local, and international governmental policies and initiatives designed to reduce the transmission of COVID-19 also have resulted in the cancellation or delay of diagnostic, elective, specialty and other procedures and appointments to avoid non-essential patient exposure to medical environments and potential infection with COVID-19 and to focus limited resources and personnel capacity toward the treatment of COVID-19. For example, a recent NPR/Harvard poll found that, with hospitals crowded from COVID-19, one in five U.S. households has had to delay care for serious illnesses in the past few months. These measures and challenges will likely continue to varying degrees for the duration of the pandemic and have significantly reduced patient access to, and administration of, certain of our drugs. For example, Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> requires administration by a healthcare provider in doctors&#8217; offices or other healthcare settings that are affected by COVID-19. The U.S. label for Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> instructs healthcare professionals who discontinue Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> to transition the patient to an alternative antiresorptive, including oral treatments that do not require administration by a healthcare provider. Further, as a result of COVID-19, oncology patients, in consultation with their doctors, may be selecting therapies that are less immunosuppressive or </span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">43</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">therapies that do not require administration in a hospital setting, potentially adversely affecting certain of our products. Also, new patients have been, and are expected to continue to be, less likely to be diagnosed and/or to start therapeutics during the pandemic, and these effects, together with the lower treatment rates during the pandemic, have had, and are expected to continue to have, a cumulative negative effect on the commercial performance of our business. The decrease in diagnoses over the course of the pandemic has suppressed the volume of new patients starting treatment, which we expect to continue to impact our business for the remainder of the year. Once the pandemic subsides, we anticipate there could be a backlog of patients seeking appointments with physicians relating to a variety of medical conditions, and as a result, patients seeking treatment with certain of our products may have to navigate lower provider capacity, and this lower provider capacity could have a continued adverse effect on our sales following the opening up of various geographies and/or the end of the pandemic. Further, the effects of the COVID-19 pandemic may result in long-term shifts in preferences among healthcare professionals and patients toward treatments that do not require administration by healthcare professionals or visits to medical facilities.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">As the pandemic continues, and if conditions worsen or if the duration of the pandemic extends significantly, we expect to experience additional adverse effects on our development, operational and commercial activities, customer purchases and our collections of accounts receivable. It remains uncertain the degree to which these adverse effects would impact our future operational and commercial activities, customer purchases and our collections as conditions begin to improve. There has been a resurgence in COVID-19 infections in numerous jurisdictions to date in 2021, resulting in the reinstatement of stricter restrictions and shutdowns in a number of jurisdictions, including in the United States., Europe and Asia Pacific regions. It is expected that the pandemic will continue to ebb and flow, with different jurisdictions having higher levels of infections than others over the course of the pandemic. New variants of the SARS-CoV-2 virus have emerged, including the delta variant, and have been shown to be present in many geographies, and appear to spread more easily and quickly than other variants. Further, although some studies suggest that antibodies generated with currently authorized vaccines may be effective against these variants, it remains uncertain whether currently available vaccines will retain their efficacy against future variants of the virus. Further, even while vaccine booster shots are available for certain patients, persistent vaccine hesitancy may result in under-vaccinated populations which may prolong the duration of the COVID-19 pandemic and continue to disrupt the availability of healthcare services to the patients we serve. Jurisdictions may implement, continue or reinstate border closures, impose or reimpose prolonged quarantines and further restrict travel and business activity, which could significantly affect our ability to support our operations and customers and the ability of our employees to get to their workplaces to discover, study, develop and produce our product candidates and products, disrupt the movement of our products through the supply chain, and further prevent or discourage patients from participating in our clinical trials, seeking healthcare services and the administration of certain of our products. Further, in connection with the global outbreak and spread of COVID-19 and in an effort to increase the wider availability of needed medical products, we or our suppliers may elect to, or governments may require us or our suppliers to, allocate manufacturing capacity (for example pursuant to the U.S. Defense Production Act) in a way that adversely affects our regular operations, customer relationships and financial results. In the United States, on January 21, 2021, President Biden issued an Executive Order instructing federal agencies to use all available legal authorities, including the Defense Production Act, to improve current and future pandemic response and biological threat preparedness. The rapid reallocation of resources for the treatment and prevention of COVID-19 (including the production of COVID-19 vaccinations or related therapies, such as our agreement to contribute to the production of COVID-19 antibody therapies for Eli Lilly and Company) and/or disruptions and shortages in the global supply chain caused by the pandemic, could also result in increased competition for, or reduced availability of, materials or components used in the development, manufacturing, distribution, or administration of our products. For example, during the second quarter of 2021, an industry-wide shortage of certain lab kit supplies necessary for some activities that support our clinical trials has developed that we are actively monitoring and managing. In addition, unpredictable increases in demand for certain of our products could exceed our capacity to meet such demand, which could adversely affect our financial results and customer relationships.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The COVID-19 pandemic and the volatile global economic conditions stemming from it may precipitate or amplify the other risks described in the &#8220;Risk Factors&#8221; section of our Annual Report on Form 10-K for the year ended December 31, 2020, which could materially adversely affect our business, operations and financial conditions and results. For example, if a natural disaster or other potentially disruptive event occurs concurrently with the COVID-19 pandemic, such disaster or event could deplete our inventory levels and we could experience a disruption to our manufacturing or ability to supply our products. Further, the global pandemic has exacerbated geopolitical tensions, and some countries, such as China, may be especially vulnerable to such dynamics. If relations between the United States and China or other governments deteriorates, our business and investments in China or other such markets may also be adversely affected. See our Annual Report on Form 10-K for the year ended December 31, 2020, Part I, Item 1A. Risk Factors&#8212;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Our sales and operations are subject to the risks of doing business internationally, including in emerging markets.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The rapid development and fluidity of the pandemic preclude any prediction as to the ultimate effect of COVID-19 on us. The duration of the measures being taken by the authorities to mitigate against the spread of COVID-19 (including the distribution and/or availability of vaccines), and the extent to which such measures are effective, if at all, remain highly uncertain. The magnitude and degree of COVID-19&#8217;s adverse effect on our business (including our product development, </span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">44</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">product sales, operating results and resulting cash flows) and financial condition will be driven by the severity and duration of the pandemic, the pandemic&#8217;s effect on the United States and global economies and the timing, scope and effectiveness of federal, state, local and international governmental responses to the pandemic. If mitigation of the pandemic continues to require further shelter-in-place and shutdown orders and/or restrictions on individual and/or group conduct, any adverse effects of the COVID-19 pandemic will likely grow and could be enduring and our business and financial position could be materially adversely affected.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">A breakdown, cyberattack or information security breach could compromise the confidentiality, integrity and availability of our information technology systems, network-connected control systems and/or our data, interrupt the operation of our business and/or affect our reputation.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">To achieve our business objectives, we rely on sophisticated information technology systems, including software, mobile applications, cloud services and network-connected control systems, some of which are managed, hosted, provided or serviced by third parties. Internal or external events that compromise the confidentiality, integrity and availability of our systems and data may significantly interrupt the operation of our business, result in significant costs and/or adversely affect our reputation.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our information technology systems are highly integrated into our business, including our R&amp;D efforts, our clinical and commercial manufacturing processes and our product sales and distribution processes. Further, as the majority of our employees are working remotely, our reliance on our and third-party information technology systems has increased substantially and is expected to continue to increase. The complexity and interconnected nature of our systems makes them potentially vulnerable to breakdown or other service interruptions. Upgrades or changes to our systems or the software that we use may result in the introduction of new cybersecurity vulnerabilities and risks. Our systems are also subject to frequent cyberattacks. As the cyber-threat landscape evolves, these attacks are growing in frequency, sophistication and intensity and are becoming increasingly difficult to detect. Such attacks could include the use of harmful and virulent malware, including ransomware or other denials of service, that can be deployed through various means, including the software supply chain, e-mail, malicious websites and/or the use of social engineering. We have also experienced unsuccessful denial of service attacks against our network, and although such attacks did not succeed, there can be no assurance that our efforts to guard against the wide and growing variety of potential attack techniques will be successful in the future. Attacks such as those experienced by governmental entities (including those that approve and/or regulate our products, such as the European Medicines Agency (EMA)) and other multi-national companies, including some of our peers, could leave us unable to utilize key business systems or access or protect important data, and could have a material adverse effect on our ability to operate our business, including developing, gaining regulatory approval for, manufacturing, selling and/or distributing our products. For example, in 2017, a pharmaceutical company experienced a cyberattack involving virulent malware that significantly disrupted its operations, including its research and sales operations and the production of some of its medicines and vaccines. As a result of the cyberattack, its orders and sales for certain products in certain markets were negatively affected. In December 2020, SolarWinds Corporation, a leading provider of software for monitoring and managing information technology infrastructure, disclosed that it had suffered a cybersecurity incident whereby attackers had inserted malicious code into legitimate software updates for its products that were installed by myriad private and government customers, enabling the attackers to access a backdoor to such systems. See our Annual Report on Form 10-K for the year ended December 31, 2020</span><span style="color:#212529;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Part I, Item 1A. Risk Factors&#8212;</span><span style="color:#212529;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">The COVID-19 pandemic, and the public and governmental effort to mitigate against the spread of the disease, have had, and are expected to continue to have, an adverse effect, and may have a material adverse effect, on our clinical trials, operations, supply chains, distribution systems, product development, product sales, business and results of operations</span><span style="color:#212529;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> for a discussion of the cyberattack on the EMA.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our systems also contain and utilize a high volume of sensitive data, including intellectual property, trade secrets, financial information, regulatory information, strategic plans, sales trends and forecasts, litigation materials and/or personal information belonging to us, our staff, our patients, customers and/or other parties. In some cases, we utilize third-party service providers to process, store, manage or transmit such data, which may increase our risk. Intentional or inadvertent data privacy or security breaches (including cyberattacks) resulting from attacks or lapses by employees, service providers (including providers of information technology-specific services), nation states (including groups associated with or supported by foreign intelligence agencies), organized crime organizations, &#8220;hacktivists&#8221; or others, create risks that our sensitive data may be exposed to unauthorized persons, our competitors, or the public. For example, a supplier recently experienced a data breach in which an unauthorized third party acquired access to certain information provided to the supplier in the course of its provision of services to us, including business documents and certain personally identifiable patient information (not including social security or other financial or health insurance information). As required, we promptly notified the applicable state attorneys general and the individuals whose personally identifiable information was affected of this data breach at the supplier. Although the supplier data breach did not result in a material adverse effect on our business, there can be no assurance that a similar future cybersecurity incident would not result in a material adverse effect on our business or results of operations. Another vendor experienced a cyberattack and, while initially reporting that our information was not involved, the vendor subsequently informed us that the attacker had accessed limited, non-significant information. Although this breach did not have a significant </span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">45</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">adverse effect on us, we may not receive timely reporting of future breaches.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Domestic and global government regulators, our business partners, suppliers with whom we do business, companies that provide us or our partners with business services, and companies we have or may acquire face similar risks, and security breaches of their systems or service outages could adversely affect our security, leave us without access to important systems, products, raw materials, components, services or information or expose our confidential data or sensitive personal information. For example, in 2019, two vendors that perform testing and analytical services that we use in developing and manufacturing our products have experienced cyberattacks, and in April and September of 2020, vendors that provide us with information technology services and clinical data services, respectively, each experienced ransomware attacks. Although there was no breach of our systems, each of these incidents required us to disconnect our systems from those vendors&#8217; systems. While we were able to reconnect our systems following restoration of these vendors&#8217; capabilities without significantly affecting product availability, a more extended service outage affecting these or other vendors, particularly where such vendor is the single source from which we obtain the services, could have a material adverse effect on our business or results of operations. In addition, we distribute our products in the United States primarily through three pharmaceutical wholesalers, and a security breach that impairs the distribution operations of our wholesalers could significantly impair our ability to deliver our products to healthcare providers and patients.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Although we have experienced system breakdowns, attacks and information security breaches, we do not believe such breakdowns, attacks and breaches have had a material adverse effect on our business or results of operations. We continue to invest in the monitoring, protection and resilience of our critical and/or sensitive data and systems. However, there can be no assurances that our efforts will detect, prevent or fully recover systems or data from all breakdowns, service interruptions, attacks and/or breaches of our systems that could adversely affect our business and operations and/or result in the loss or exposure of critical, proprietary, private, confidential or otherwise sensitive data, which could result in material financial, legal, business or reputational harm to us or negatively affect our stock price. While we maintain cyber-liability insurance, our insurance is not sufficient to cover us against all losses that could potentially result from a service interruption, breach of our systems or loss of our critical or sensitive data.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We are also subject to various laws and regulations globally regarding privacy and data protection, including laws and regulations relating to the collection, storage, handling, use, disclosure, transfer and security of personal data. The legislative and regulatory environment regarding privacy and data protection is continuously evolving and developing and the subject of significant attention globally. For example, we are subject to the European Union&#8217;s General Data Protection Regulation, which became effective in May 2018, and the California Consumer Privacy Act of 2018 (CCPA), which became effective in January 2020, both of which provide for substantial penalties for non-compliance. The CCPA was amended in late 2020, to create the California Privacy Rights Act to create opt-in requirements for the use of sensitive personal data and the formation of a new dedicated agency for the enforcement of the law, the California Privacy Protection Agency. Since then, Virginia and Colorado both passed similar consumer privacy laws that will go into effect in 2023. Other jurisdictions where we operate continue to propose similar legislation and/or regulations with others expected to pass in 2021. Failure to comply with these current and future laws could result in significant penalties and reputational harm and could have a material adverse effect on our business and results of operations.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">RISKS RELATED TO GOVERNMENT REGULATIONS AND THIRD-PARTY POLICIES</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Our sales depend on coverage and reimbursement from government and commercial third-party payers, and pricing and reimbursement pressures have affected, and are likely to continue to affect, our profitability.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Sales of our products depend on the availability and extent of coverage and reimbursement from third-party payers, including government healthcare programs and private insurance plans. Governments and private payers continue to pursue initiatives to manage drug utilization and contain costs. These payers are increasingly focused on the effectiveness, benefits and costs of similar treatments, which have resulted, and are expected to continue to result, in lower reimbursement rates for our products or narrower populations for whom payers will reimburse. Continued intense public scrutiny of the price of drugs and other healthcare costs, together with payer dynamics, have limited, and are likely to continue to limit, our ability to set or adjust the price of our products based on their value, which can have a material adverse effect on our business. In the United States, particularly over the past few years, a number of legislative and regulatory proposals have been introduced in an attempt to lower drug prices. These include proposals that would allow the U.S. government to negotiate drug prices directly, limit drug reimbursement in Medicare and/or the commercial market based on a reference prices or permit importation of drugs from Canada. Additional proposals would require a rebate to the government for any price increase in excess of the Consumer Price Index for All Urban Consumers and/or to shift some of the costs of these Medicare Part D reforms to manufacturers to offset the cost. Proposals focused on drug pricing have been implemented and are likely to continue to be proposed and may be adopted and implemented in some form. See our Annual Report on Form 10-K for the year ended December 31, 2020, Part I, Item 1A. Risk Factors&#8212;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Our sales depend on coverage and reimbursement from government and commercial third-party payers, and pricing and reimbursement pressures have affected, and are likely to continue to affect, our profitability.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">46</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;padding-left:36pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">&#8212;Changing U.S. federal coverage and reimbursement policies and practices have affected and may continue to affect access to, pricing and sales of our products</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">A substantial portion of our U.S. business relies on reimbursement from federal government healthcare programs and commercial insurance plans regulated by federal and state governments. See our Annual Report on Form 10-K for the year ended December 31, 2020, Part I, Item 1. Business&#8212;Reimbursement. Our business has been and will continue to be affected by legislative actions changing U.S. federal reimbursement policy. Congress has been focused on drug pricing reforms and oversight since 2018, and is ongoing. For example, in 2020, Amgen participated in House Oversight and Reform Committee hearings on drug pricing practices. Additionally, in 2019 and 2020, a number of other Congressional committees debated drug pricing reform proposals. For example, in 2019, the Senate Finance Committee advanced a bill that would, among other things, penalize pharmaceutical manufacturers for raising prices on drugs covered by Medicare Parts B and/or D faster than the rate of inflation, cap out-of-pocket expenses for Medicare Part D beneficiaries and require higher/additional manufacturer discounts in Medicare Part D. Additionally, in late 2019, a drug-pricing bill, H.R. 3, passed the House of Representatives, which would, among other things, enable direct price negotiations by the federal government on certain drugs (with the maximum price paid by Medicare capped by prices derived from an international index), includes a penalty for failing to reach agreement with the government and requires that manufacturers offer these negotiated prices to other payers. Further, proposals from H.R. 3 have been incorporated into other proposed legislation, including the House&#8217;s drug pricing provisions based on H.R. 3 in the Build Back Better reconciliation bill, and proposals from H.R. 3 are also likely to be included in the version of the reconciliation bill that remains to be further debated between the House, Senate and White House. Other legislation has also contained drug pricing reforms, including the Infrastructure Investment and Jobs Act passed by the Senate in August 2021, which includes a provision that would, starting in 2023, require manufacturers to provide Medicare with rebates for certain drugs paid under Medicare Part B, and the American Rescue Plan Act of 2021, which includes a provision, to be implemented in 2024, that increases the Medicaid rebate liability for certain medicines that raise prices in excess of inflation. On November 2, 2021, Congress announced a framework for drug pricing reform that includes inflation penalties, Medicare negotiation for select drugs paid for under Parts B and D, and a Medicare Part D redesign. As of the date of this filing, this framework remains in discussion with policymakers in Congress and the Administration.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">There are other outstanding proposals that have been introduced by the prior Administration that, if enacted and implemented in whole or in part, could also affect access to and sales of our products, including, but not limited to, proposals to allow importation of prescription medications from Canada or other countries and to set Medicare payment rates using international price referencing. Further, in mid-2020, the prior Administration announced a number of Executive Orders intended to reduce the cost of biopharmaceuticals for patients, including a most favored nation (MFN) policy for Medicare Parts B and D, under which the Health &amp; Human Services (HHS) was directed to take steps to implement payment models that set Medicare purchase prices based on the lowest price available in economically comparable countries for certain Part B and Part D medicines. In September 2020, in response to the corresponding Executive Order, HHS released a final rule to allow states (or other nonfederal government entities) to submit proposals to the FDA allowing for the importation of certain nonbiologic prescription drugs from Canada. Currently, the rule is being challenged by litigation, however, should such litigation be unsuccessful and should the Secretary of HHS authorize state proposals for importation, this rule could allow the importation of Canadian versions of certain of Amgen&#8217;s products (including Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">), that could have a material adverse effect on Amgen&#8217;s business. Further, in November 2020, also in response to the corresponding Executive Order, HHS released an interim final rule to implement the MFN pricing approach. If implemented, the MFN rule would set the reimbursement rate for 50 Medicare Part B drugs (including our products, such as Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, Nplate</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, EPOGEN</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> and Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">) equal to the lowest adjusted price for such products of the 22 OECD nations. Lawsuits have been filed by certain trade groups challenging the implementation of this MFN rule based on, among other things, procedural defects. Late in 2020, in the case filed by the Biotechnology Innovation Organization (BIO) and others, the U.S. District Court for the Northern District of California issued a preliminary injunction preventing the rule from taking effect nationwide, pending the government&#8217;s completion of required administrative procedures. The case was subsequently stayed by the court and will remain stayed until at least November 10, 2021, when the parties will be required to submit a joint status report to the court. Another case, filed by the Pharmaceutical Research and Manufacturers of America and others in the U.S. District Court for the District of Maryland, was also stayed until either a final rule based on the MFN interim rule is published in the Federal Register, or until the court orders a lifting of the stay based on, among other things, the status of the nationwide preliminary injunction issued in the BIO case. In August 2021, Centers for Medicare &amp; Medicaid Services (CMS) released a proposal to withdraw the MFN rule, noting, however, that the proposal to withdraw &#8220;does not reflect any judgment by HHS regarding future policy.&#8221;</span><span style="background-color:#f1f1f1;color:#333333;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Notwithstanding these stays and the proposed withdrawal of the rule, the MFN rule&#8217;s approach to drug pricing and other similar approaches remain of interest. Further, despite the change in Administration, we expect continued significant focus on healthcare and similar drug pricing proposals for the foreseeable future, including proposals similar to the MFN rule or other proposals that would grant the HHS secretary the authority to negotiate drug prices directly with manufacturers. On July 9, 2021, the Administration issued an Executive Order designed to address anticompetitive behavior across multiple sectors, and for the healthcare sector, called for, among other things, more scrutiny of anticompetitive activity by the Federal Trade </span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">47</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Commission (FTC), emphasized the need for actions to allow for greater competition from generics and biosimilars, and called for the FDA to work with states and Indian Tribes to develop prescription drug importation programs. The Executive Order established a process and timeline for federal agencies to deliver ideas on drug pricing to the Administration, including requiring HHS to develop a comprehensive plan within 45 days to address drug pricing. Subsequently, on September 9, 2021, the HHS released a report that presented guiding principles for the Administration&#8217;s drug pricing proposals, including changes to promote competition throughout the prescription drug industry, highlighting potential legislative policies that Congress could pursue (including drug price negotiation in Medicare Parts B and D, making those negotiated prices available to commercial plans and legislation to speed the entry of biosimilar and generic drugs) and examples of potential administrative tools available to the HHS (including various testing models and enhanced focus of the FTC and the USPTO to address impediments to generic drug and biosimilar competition). Also in response to the July 9 Executive Order, the FDA sent a letter to the USPTO describing ways to strengthen coordination between the two agencies, offered training to help identify prior art, and seeking USPTO&#8217;s views on practices that extend market exclusivities, whether pharmaceutical patent examiners need additional resources, and the effect of post-grant challenges at the PTAB on drug patents.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our business has been, and is expected to continue to be, affected by changes in U.S. federal reimbursement policy resulting from federal regulations and federal demonstration projects. Over the past three years, federal agencies, including the CMS, announced a number of recommendations, policies, proposals and demonstration projects addressing drug pricing. CMS is the federal agency responsible for administering Medicare and overseeing state Medicaid programs and Health Insurance Marketplaces and has substantial power to implement policy changes or demonstration projects that can quickly and significantly affect how drugs, including our products, are covered and reimbursed. CMS issued guidance to allow certain Medicare plans offered by private insurance companies to require that patients receiving Medicare Part B drugs first try a drug preferred by the plan before covering another therapy (Step Therapy) and lowered reimbursement rates for new Medicare Part B drugs. Further, HHS issued a final rule under Medicare Part D revising the regulations under the federal antikickback statute to encourage Pharmacy Benefit Managers (PBMs) to use rebates received from biopharmaceutical manufacturers to reduce patient cost-sharing at the point of sale. While the implementation date for the rule is January 1, 2023, the rule remains subject to litigation, there are numerous logistical hurdles to overcome before it can be effectively implemented, and it is unclear how PBMs will respond and what the current Administration&#8217;s position is on the rule. Further, while the prior Administration finalized a rule (effective January 1, 2022) mandating price and cost-sharing transparency for almost all health plans and insurers in the individual and group commercial markets, the current Administration has delayed implementation of those drug price transparency provisions and has indicated that there will be future rulemaking on the issue. It is unclear how group health plans and health insurers may respond. The Administration also could develop and seek to advance a range of policy proposals that could impact U.S. federal reimbursement policy for drugs and biologics, including changes to Medicare Part B.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">CMS policy changes and demonstration projects to test new care, delivery and payment models can significantly affect how drugs, including our products, are covered and reimbursed. In end-stage renal disease (ESRD), CMS uses bundled payment rates. Between 2018 and 2020, Sensipar</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> and Parsabiv</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, our calcimimetics that are used in dialysis clinics, were eligible for temporary drug add-on payment adjustments (TDAPA) to the bundled rate. In November 2020, CMS released its final rule ending the TDAPA for calcimimetics and adjusting ESRD Prospective Payment System bundled rates on January 1, 2021 by $9.93 per dialysis treatment for calcimimetics. As a result, sales of Parsabiv</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> have been materially adversely affected by this rule change. Additionally, CMS created a new mandatory payment model, effective January 1, 2021, focused on encouraging greater use of home dialysis and kidney transplants for ESRD patients that could result in changes to treatment of dialysis patients, including reduction of the use of our ESAs. Further, in November 2019, CMS announced additional voluntary payment models for nephrologists and dialysis facility partners that also seek to encourage home dialysis and preemptive transplantation through increased risk sharing, effective January 1, 2022. CMS has also solicited suggestions regarding other potential care models. In 2016, CMS initiated the Oncology Care Model demonstration, which provides participating physician practices with performance-based financial incentives that aim to manage or reduce Medicare costs without negatively affecting the efficacy of care, that has been extended by one year (to 2022) due to COVID-19. We believe the Oncology Care Model has reduced utilization of certain of our oncology products by participating physician practices and expect it to continue to do so in the future. Additionally, in late 2019, CMS announced a request for information on the Oncology Care First model, a new voluntary model that builds on the Oncology Care Model. CMS has indicated a continued interest in exploring demonstrations of mandatory models, and may propose both new mandatory payment models in the future that could adversely affect our business. For example, HHS&#8217;s September 2021 comprehensive plan to address drug pricing included potential future mandatory models that link payment for prescription drugs and biologics to factors such as: improved patient outcomes, reductions in health disparities, patient affordability, and lower overall costs; bundled payment models; total cost of care models; models in which Medicare Part B savings from utilization of biosimilars, generics, or other high-value products are shared between prescribing providers and the government; models that provide additional Medicare Part D cost-sharing support for biosimilars and generics; and potential expansion of the Part D Senior Savings Model to additional classes of drugs. CMS recently finalized a rule that, starting January 1, 2023, unless a manufacturer can ensure that the full amount of manufacturer patient assistance programs is passed on to the patient, such amount will be treated as a price reduction that will be taken into account when </span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">48</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">reporting our Best Price and/or Average Manufacturer Price. Given the use by PBMs and insurers of copay accumulator adjustment programs to apply such patient assistance for the benefit of such companies and not to defray costs to patients, it could be difficult to impossible for manufacturers to ensure that the full value of such amounts is being passed on to the patient. This new policy, if implemented, would have significant implications for our ability to offer copay assistance programs. In this dynamic environment, particularly in light of the pressures on healthcare budgets as a result of the pandemic, we are unable to predict which or how many federal policy, legislative, regulatory, executive or administrative changes may ultimately be, or effectively estimate the consequences to our business if, enacted and implemented. However, to the extent that these or other federal government initiatives further decrease or modify the coverage or reimbursement available for our products, require that we pay increased rebates or shift other costs to us, limit or affect our decisions regarding the pricing of or otherwise reduce the use of our U.S. products, or limit our ability to offer co-pay payment assistance to commercial patients, such actions could have a material adverse effect on our business and results of operations.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We also face risks relating to the reporting of pricing data that affects the reimbursement of and discounts provided for our products. U.S. government price reporting regulations are complex and may require a biopharmaceutical manufacturer to update certain previously submitted data. If our submitted pricing data are incorrect, we may become subject to substantial fines and penalties or other government enforcement actions, which could have a material adverse effect on our business and results of operations. In addition, as a result of restating previously reported price data, we also may be required to pay additional rebates and provide additional discounts.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">The adoption and interpretation of new tax legislation or exposure to additional tax liabilities could affect our profitability.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We are subject to income and other taxes in the United States and other jurisdictions in which we do business. As a result, our provision for income taxes is derived from a combination of applicable tax rates in the various places we operate. Significant judgment is required for determining our provision for income tax.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">One or more of our legal entities file income tax returns in the U.S. federal jurisdiction, various U.S. state jurisdictions and certain foreign jurisdictions. Our income tax returns are routinely examined by tax authorities in those jurisdictions. Significant disputes can arise with tax authorities involving issues regarding the timing and amount of deductions, the use of tax credits and allocations of income and expenses among various tax jurisdictions because of differing interpretations of tax laws, regulations and relevant facts, and such tax authorities (including the IRS) are becoming more aggressive in their audits and are particularly focused on such matters. In 2017, we received a RAR and a modified RAR from the IRS for the years 2010, 2011 and 2012 proposing significant adjustments that primarily relate to the allocation of profits between certain of our entities in the United States and the U.S. territory of Puerto Rico. As previously reported, we disagreed with the proposed adjustments and calculations and pursued a resolution with the IRS administrative appeals office. However, we were unable to reach resolution with the IRS appeals office. In July 2021, we filed a petition in the U.S. Tax Court to contest two duplicative Notices for 2010, 2011 and 2012 that we received in May and July 2021 which seek to increase our U.S. taxable income. We firmly believe that the IRS&#8217;s positions set forth in the Notices are without merit, and we will vigorously contest the Notices through the judicial process. See Note 4, Income taxes, to the condensed consolidated financial statements.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In addition, in 2020, we received an RAR and a modified RAR from the IRS for the years 2013, 2014 and 2015 also proposing significant adjustments that primarily relate to the allocation of profits between certain of our entities in the United States and the U.S. territory of Puerto Rico similar to those proposed for the years 2010, 2011 and 2012. We disagree with the proposed adjustments and calculations and have been pursuing resolution with the IRS administrative appeals office. As a consequence of the 2010-2012 Tax Court litigation, the IRS administrative appeals office recently informed us that it does not plan to engage in discussions at this time regarding the allocation of profits between our entities in the United States and the U.S. territory of Puerto Rico for the 2013-2015 period. We are currently under examination by the IRS for the years 2016, 2017 and 2018. We are also currently under examination by a number of other state and foreign tax jurisdictions.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Final resolution of these complex matters is not likely within the next 12 months. We continue to believe our accrual for income tax liabilities is appropriate based on past experience, interpretations of tax law, application of the tax law to our facts and judgments about potential actions by tax authorities; however, due to the complexity of the provision for income taxes and uncertain resolution of these matters, the ultimate outcome of any tax matters may result in payments substantially greater than amounts accrued and could have a material adverse effect on the results of our operations. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our provision for income taxes and results of operations in the future could be adversely affected by changes to our operating structure, changes in the mix of income and expenses in countries with differing tax rates, changes in the valuation of deferred tax assets and liabilities and changes in applicable tax laws, regulations or administrative interpretations thereof. The Tax Cuts and Jobs Act (the 2017 Tax Act) is complex and a large volume of regulations and guidance has been issued and could be subject to different interpretations. We could face audit challenges to our application of the 2017 Tax Act. The Administration and Congress are considering significant changes to existing tax law, including an increase in the corporate tax </span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">49</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">rate and the tax rate on foreign earnings. These changes could substantially increase U.S. taxation of our operations both in and outside the United States, including the U.S. territory of Puerto Rico. Further, the OECD recently reached agreement to align countries on a minimum corporate tax rate and an expansion of the taxing rights of market countries. If enacted, this agreement could result in tax increases in both the United States and foreign jurisdictions</span><span style="color:#008080;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">. </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Changes to existing tax law in the United States, the U.S. territory of Puerto Rico, or other jurisdictions that would likely result in tax increases where we do business and could have a material adverse effect on the results of our operations.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_121"></div><div style="text-align:justify"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.853%"><tr><td style="width:1.0%"></td><td style="width:9.880%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:87.920%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Item&#160;2.</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS</span></td></tr></table></div><div style="margin-bottom:8pt;margin-top:10pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">During the three months ended September 30, 2021, we had one outstanding stock repurchase program, under which the repurchase activity was as follows:</span></div><div><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:33.549%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:14.543%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:14.543%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:14.397%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.530%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:14.548%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Period</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total number<br/>of shares<br/>purchased</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Average</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">price paid</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">per share </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:5.2pt;font-weight:700;line-height:100%;position:relative;top:-2.8pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total number<br/>of shares purchased<br/>as part of publicly announced program</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Maximum dollar</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">value that may</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">yet be purchased</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">under the program</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:5.2pt;font-weight:700;line-height:100%;position:relative;top:-2.8pt;vertical-align:baseline">(2)</span></div></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">July 1 - 31</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,763,784&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">245.52&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,763,784&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,486,312,736&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">August 1 - 31</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250,282&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">226.31&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250,282&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,203,364,954&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">September 1 - 30</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,624,898&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">217.23&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,624,898&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,850,385,563&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,638,964&#160;</span></td><td style="border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">230.43&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,638,964&#160;</span></td><td style="border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr></table></div><div style="text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">___________</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">(1)&#160;&#160;&#160;&#160;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Average price paid per share includes related expenses.</span></div><div style="padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">(2)</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;In March 2021, our Board of Directors increased the amount authorized under our stock repurchase program by an additional $3.4 billion. In October 2021, the Board of Directors increased the amount authorized under our stock repurchase program by an additional $4.5 billion.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">50</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span><br/></span></div><div id="i0b2dd96150e340208a57faec23ec2da5_124"></div><div style="text-align:justify"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:30.409%"><tr><td style="width:1.0%"></td><td style="width:34.957%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:62.843%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Item&#160;6.&#160;</span></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">EXHIBITS</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Reference is made to the Index to Exhibits included herein.</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">51</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_127"></div><hr style="page-break-after:always"/><div style="min-height:40.5pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="-sec-extract:summary;margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">INDEX TO EXHIBITS</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.415%"><tr><td style="width:1.0%"></td><td style="width:9.635%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:2.005%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:85.960%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Exhibit&#160;No.</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Description</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.1</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312519228830/d787825dex21.htm">Asset Purchase Agreement, dated August 25, 2019, by and between Amgen Inc. and Celgene Corporation.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on August 26, 2019 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.2</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312519270139/d655928dex101.htm">Amendment No. 1 to the Asset Purchase Agreement, dated October 17, 2019, by and between Amgen Inc. and Celgene Corporation.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on October 17, 2019 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.3</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000017/a23amendmentno2toapa.htm">Amendment No. 2 to the Asset Purchase Agreement, dated October 17, 2019, by and between Amgen Inc. and Celgene Corporation.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2019 on February 12, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.4</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000017/a24letteragreementv3.htm">Letter Agreement, dated November 21, 2019, by and between Amgen Inc. and the parties named therein re: Treatment of Certain Product Inventory in connection with Amgen&#8217;s acquisition of Otezla</a></span><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:100%;position:relative;text-decoration:underline;top:-3.5pt;vertical-align:baseline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:100%;position:relative;text-decoration:underline;top:-3.5pt;vertical-align:baseline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000017/a24letteragreementv3.htm">&#174;</a></span><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000017/a24letteragreementv3.htm">.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2019 on February 12, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.5</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312519228830/d787825dex22.htm">Irrevocable Guarantee, dated August 25, 2019, by and between Amgen Inc. and Bristol-Myers Squibb Company.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on August 26, 2019 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.6</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312521068571/d151856dex21.htm">Agreement and Plan of Merger, dated as of March 4, 2021, by and among Amgen Inc., Franklin Acquisition Sub, Inc. and Five Prime Therapeutics, Inc.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on March 4, 2021 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.7*</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="amgn-ex27_202193021xq3.htm">Agreement and Plan of Merger, dated July 27, 2021, by and among Amgen Inc., Teneobio, Inc., Tuxedo Merger Sub, Inc., and Fortis Advisors LLC.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (portions of the exhibit have been omitted because they are both (i) not material and (ii) is the type of information that the Company treats as private or confidential).</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.1</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000144530513001107/amgn-exh31_2013331xq1.htm">Restated Certificate of Incorporation of Amgen Inc.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (As Restated March 6, 2013.) (Filed as an exhibit to Form 10-Q for the quarter ended March 31, 2013 on May 3, 2013 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.2</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312516466178/d46204dex31.htm">Amended and Restated Bylaws of Amgen Inc.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (As Amended and Restated February 15, 2016.) (Filed as an exhibit to Form 8-K on February 17, 2016 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.1</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/0000318154-97-000008.txt">Form of stock certificate for the common stock, par value $.0001 of the Company.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended March 31, 1997 on May 14, 1997 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.2</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Form of Indenture, dated January 1, 1992. (Filed as an exhibit to Form S-3 Registration Statement filed on December 19, 1991 and incorporated herein by reference.)</span></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.3</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312508040431/dex43.htm">Agreement of Resignation, Appointment and Acceptance dated February 15, 2008.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2007 on February 28, 2008 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.4</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/0000898430-97-001006.txt">First Supplemental Indenture, dated February 26, 1997.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on March 14, 1997 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.5</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/0000898430-97-001433.txt">8-1/8% Debentures due April 1, 2097.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on April 8, 1997 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.6</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/0000898430-97-001433.txt">Officer&#8217;s Certificate of Amgen Inc., dated April 8, 1997, establishing a series of securities entitled &#8220;8 1/8% Debentures due April 1, 2097.&#8221;</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on April 8, 1997 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.7</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000104746903026118/a2115639zex-4_1.htm">Indenture, dated August 4, 2003.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form S-3 Registration Statement on August 4, 2003 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.8</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/0000318154-98-000005.txt">Corporate Commercial Paper - Master Note between and among Amgen Inc., as Issuer, Cede &amp; Co., as Nominee of The Depository Trust Company, and Citibank, N.A., as Paying Agent.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended March&#160;31, 1998 on May&#160;13, 1998 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.9</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312507126045/dex42.htm">Officers&#8217; Certificate of Amgen Inc., dated May 30, 2007, including form of the Company&#8217;s 6.375% Senior Notes due 2037.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on May 30, 2007 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.10</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312508121768/dex42.htm">Officers&#8217; Certificate of Amgen Inc., dated May 23, 2008, including form of the Company&#8217;s 6.90% Senior Notes due 2038</a>.</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as exhibit to Form 8-K on May 23, 2008 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr></table></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="-sec-extract:summary;margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">52</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:40.5pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.415%"><tr><td style="width:1.0%"></td><td style="width:9.635%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:2.005%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:85.960%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.11</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312509007552/dex42.htm">Officers&#8217; Certificate of Amgen Inc., dated January 16, 2009, including form of the Company&#8217;s 6.40% Senior Notes due 2039.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as exhibit to Form 8-K on January 16, 2009 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.12</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312510055545/dex42.htm">Officers&#8217; Certificate of Amgen Inc., dated March 12, 2010, including form of the Company&#8217;s 5.75% Senior Notes due 2040.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as exhibit to Form 8-K on March 12, 2010 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.13</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312510211595/dex42.htm">Officers&#8217; Certificate of Amgen Inc., dated September 16, 2010, including form of the Company&#8217;s 4.95% Senior Notes due 2041.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on September 17, 2010 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.14</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312511178620/dex42.htm">Officers&#8217; Certificate of Amgen Inc., dated June 30, 2011, including form of the Company&#8217;s 5.65% Senior Notes due 2042.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on June 30, 2011 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.15</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312511306300/d254287dex42.htm">Officers&#8217; Certificate of Amgen Inc., dated November 10, 2011, including form of the Company&#8217;s 5.15% Senior Notes due 2041.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on November 10, 2011 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.16</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312511329468/d265264dex42.htm">Officers&#8217; Certificate of Amgen Inc., dated December 5, 2011, including form of the Company&#8217;s 5.50% Senior Notes due 2026.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on December 5, 2011 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.17</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312512234621/d352967dex42.htm">Officers&#8217; Certificate of Amgen Inc., dated May 15, 2012, including forms of the Company&#8217;s 3.625% Senior Notes due 2022 and 5.375% Senior Notes due 2043.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on May 15, 2012 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.18</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312512390074/d410209dex42.htm">Officers&#8217; Certificate of Amgen Inc., dated September 13, 2012, including form of the Company&#8217;s 4.000% Senior Notes due 2029.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on September 13, 2012 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.19</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312514209848/d732359dex41.htm">Indenture, dated May 22, 2014, between Amgen Inc. and The Bank of New York Mellon Trust Company, N.A., as Trustee.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on May 22, 2014 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.20</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312514209848/d732359dex42.htm">Officers&#8217; Certificate of Amgen Inc., dated May 22, 2014, including form of the Company&#8217;s 3.625% Senior Notes due 2024.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on May 22, 2014 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.21</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312515165541/d919213dex42.htm">Officer&#8217;s Certificate of Amgen Inc., dated May 1, 2015, including forms of the Company&#8217;s 2.700% Senior Notes due 2022, 3.125% Senior Notes due 2025 and 4.400% Senior Notes due 2045.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit on Form 8-K on May 1, 2015 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.22</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312516476783/d129782dex42.htm">Officer&#8217;s Certificate of Amgen Inc., dated as of February 25, 2016, including forms of the Company&#8217;s 1.250% Senior Notes due 2022 and 2.000% Senior Notes due 2026.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit on Form 8-K on February 26, 2016 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.23</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312516495970/d156859dex41.htm">Form of Permanent Global Certificate for the Company&#8217;s 0.410% bonds due 2023.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit on Form 8-K on March 8, 2016 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.24</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312516495970/d156859dex42.htm">Terms of the Bonds for the Company&#8217;s 0.410% bonds due 2023.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit on Form 8-K on March 8, 2016 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.25</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312516621372/d203675dex42.htm">Officer&#8217;s Certificate of Amgen Inc., dated as of June 14, 2016, including forms of the Company&#8217;s 4.563% Senior Notes due 2048 and 4.663% Senior Notes due 2051.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on June 14, 2016 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.26</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312516686451/d187158dex43.htm">Officer&#8217;s Certificate of Amgen Inc., dated as of August 19, 2016, including forms of the Company&#8217;s 2.250% Senior Notes due 2023 and 2.600% Senior Notes due 2026.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on August 19, 2016 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.27</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312517167330/d389370dex42.htm">Officer&#8217;s Certificate of Amgen Inc., dated as of May 11, 2017 including form of the Company&#8217;s 2.650% Senior Notes due 2022.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on May 11, 2017 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.28</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312517331065/d472956dex42.htm">Officer&#8217;s Certificate of Amgen Inc., dated as of November 2, 2017, including in the form of the Company&#8217;s 3.200% Senior Notes due 2027.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on November 2, 2017 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.29</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312520044757/d894000dex42.htm">Officer&#8217;s Certificate of Amgen Inc., dated as of February 21, 2020, including forms of the Company&#8217;s 1.900% Senior Notes due 2025, 2.200% Senior Notes due 2027, 2.450% Senior Notes due 2030, 3.150% Senior Notes due 2040 and 3.375% Senior Notes due 2050.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on February 21, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr></table></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="-sec-extract:summary;margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">53</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:40.5pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.415%"><tr><td style="width:1.0%"></td><td style="width:9.635%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:2.005%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:85.960%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.30</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312520134934/d925911dex43.htm">Officer&#8217;s Certificate of Amgen Inc., dated as of May 6, 2020, including form of the Company&#8217;s 2.300% Senior Notes due 2031.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on May 6, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.31</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312520222579/d60848dex42.htm">Officer&#8217;s Certificate of Amgen Inc., dated as of August 17, 2020, including forms of the Company&#8217;s 2.770% Senior Notes due 2053.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on August 18, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.32</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312520222579/d60848dex43.htm">Registration Rights Agreement, dated as of August 17, 2020, by and among Amgen Inc., BofA Securities, Inc. and J.P. Morgan Securities LLC, as lead dealer managers, and BNP Paribas Securities Corp., Deutsche Bank Securities Inc., RBC Capital Markets, LLC, Blaylock Van, LLC and Siebert Williams Shank &amp; Co., LLC, as co-dealer managers.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on August 18, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.1+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312513145924/d475543ddef14a.htm#toc475543_21">Amgen Inc. Amended and Restated 2009 Equity Incentive Plan.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as Appendix C to the Definitive Proxy Statement on Schedule 14A on April 8, 2013 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.2+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815415000010/amgn-ex102_2015331xq1.htm">First Amendment to Amgen Inc. Amended and Restated 2009 Equity Incentive Plan, effective March 4, 2015.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended March 31, 2015 on April 27, 2015 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.3+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815416000035/amgn-ex103_2016331xq1.htm">Second Amendment to Amgen Inc. Amended and Restated 2009 Equity Incentive Plan, effective March 2, 2016.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended March 31, 2016 on May 2, 2016 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.4+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815421000010/amgn-ex104_20201231xq4.htm">Form of Grant of Stock Option Agreement for the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan. (As Amended on December 15, 2020.)</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2020 on February 9, 2021 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.5+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815421000010/amgn-ex105_20201231xq4.htm">Form of Restricted Stock Unit Agreement for the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan. (As Amended on December 15, 2020.)</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2020 on February 9, 2021 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.6+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815418000004/exhibit106performanceaward.htm">Amgen Inc. 2009 Performance Award Program. (As Amended on December 12, 2017.)</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2017 on February 13, 2018 and incorporated herein by reference.)</span></div></td></tr><tr style="height:3pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.7+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815421000010/amgn-ex107_20201231xq4.htm">Form of Performance Unit Agreement for the Amgen Inc. 2009 Performance Award Program. (As Amended on December 15, 2020.)</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2020 on February 9, 2021 and incorporated herein by reference.)</span></div></td></tr><tr style="height:3pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.8+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815421000010/amgn-ex108_20201231xq4.htm">Amgen Inc. 2009 Director Equity Incentive Program. (As Amended and Restated on October 21, 2020.)</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2020 on February 9, 2021 and incorporated herein by reference.)</span></div></td></tr><tr style="height:3pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.9+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312509105621/dex107.htm">Form of Grant of Non-Qualified Stock Option Agreement for the Amgen Inc. 2009 Director Equity Incentive Program.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on May 8, 2009 and incorporated herein by reference.)</span></div></td></tr><tr style="height:3pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.10+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000017/a1010-amgenxdirectorrs.htm">Form of Restricted Stock Unit Agreement for the Amgen Inc. 2009 Director Equity Incentive Program. (As Amended on December 11, 2019.)</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2019 on February 12, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:3pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.11+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000017/a1011-amgenxdirectorca.htm">Form of Cash-Settled Restricted Stock Unit Agreement for the Amgen 2009 Director Equity Incentive Program. (As Amended on December 11, 2019.)</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2019 on February 12, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:3pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.12+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815414000004/amgn-ex109_20131231x10k.htm">Amgen Inc. Supplemental Retirement Plan. (As Amended and Restated effective October 16, 2013.)</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2013 on February 24, 2014 and incorporated herein by reference.)</span></div></td></tr><tr style="height:3pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.13+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815416000053/amgn-ex1012_2016930xq3.htm">First Amendment to the Amgen Inc. Supplemental Retirement Plan, effective October 14, 2016.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended September 30, 2016 on October 28, 2016 and incorporated herein by reference.)</span></div></td></tr><tr style="height:3pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.14+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000017/a1014-secondamendmento.htm">Second Amendment to the Amgen Inc. Supplemental Retirement Plan (As Amended and Restated effective October 23, 2019).</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2019 on February 12, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.15+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000095012311048073/v58996exv10w9.htm">Amended and Restated Amgen Change of Control Severance Plan. (As Amended and Restated effective December 9, 2010 and subsequently amended effective March 2, 2011.)</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended March 31, 2011 on May 10, 2011 and incorporated herein by reference.)</span></div></td></tr></table></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="-sec-extract:summary;margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">54</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:40.5pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.415%"><tr><td style="width:1.0%"></td><td style="width:9.635%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:2.005%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:85.960%"></td><td style="width:0.1%"></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.16+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312508228861/dex1019.htm">Amgen Inc. Executive Incentive Plan. (As Amended and Restated effective January&#160;1, 2009.)</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended September&#160;30, 2008 on November&#160;7, 2008 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.17+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000144530513000364/amgn-ex1017_2012123110k.htm">First Amendment to the Amgen Inc. Executive Incentive Plan, effective December 13, 2012.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2012 on February 27, 2013 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.18+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815417000009/amgn-ex1016_2017033110q.htm">Second Amendment to the Amgen Inc. Executive Incentive Plan, effective January 1, 2017.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended March 31, 2017 on April 27, 2017 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.19+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815414000004/amgn-ex1015_20131231x10k.htm">Amgen Nonqualified Deferred Compensation Plan. (As Amended and Restated effective October 16, 2013.)</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2013 on February 24, 2014 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.20+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815416000053/amgn-ex1017_2016930xq3.htm">First Amendment to the Amgen Nonqualified Deferred Compensation Plan, effective October 14, 2016.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended September 30, 2016 on October 28, 2016 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.21+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000017/a1021-secondamendmentt.htm">Second Amendment to the Amgen Nonqualified Deferred Compensation Plan</a><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000017/a1021-secondamendmentt.htm">, effective January 1, 2020.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">  (Filed as an exhibit to Form 10-K for the year ended December 31, 2019 on February 12, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.22+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815418000022/exhibit1023agmtamgenincand.htm">Agreement between Amgen Inc. and Murdo Gordon, dated July 25, 2018.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended September 30, 2018 on October 31, 2018 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.23+</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:115%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:115%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000031/petergriffith-signedof.htm">Agreement between Amgen Inc. and Peter Griffith, dated October 18, 2019.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:115%"> (Filed as an exhibit to Form 10-Q for the quarter ended March 31, 2020 on May 1, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.24</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312519312129/d834361dex101.htm">Second Amended and Restated Credit Agreement, dated December 12, 2019, among Amgen Inc., the Banks therein named, Citibank, N.A., as administrative agent, and JPMorgan Chase Bank, N.A., as syndication agent</a>.</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 8-K on December 12, 2019 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.25</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312513312834/d573775dex1054.htm">Collaboration and License Agreement between Amgen Inc. and Celltech R&amp;D Limited dated May 10, 2002 (portions of the exhibit have been omitted pursuant to a request for confidential treatment) and Amendment No. 1, effective June 9, 2003, to Collaboration and License Agreement between Amgen Inc. and Celltech R&amp;D Limited (portions of the exhibit have been omitted pursuant to a request for confidential treatment).</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K/A for the year ended December 31, 2012 on July 31, 2013 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.26</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="margin-bottom:2pt;margin-top:2pt;text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815417000004/amgn-ex1032_20161231x10k.htm">Amendment No. 2 to Collaboration and License Agreement, effective November 14, 2016, between Amgen Inc. and Celltech R&amp;D Limited (portions of the exhibit have been omitted pursuant to a request for confidential treatment).</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2016 on February 14, 2017 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.27</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815419000037/amgn-ex282019630xq2.htm">Letter Agreement, dated June 25, 2019, by and between Amgen Inc. and UCB Celltech (portions of the exhibit have been omitted because they are both (i) not material and (ii) would be competitively harmful if publicly disclosed).</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended June 30, 2019 on July 31, 2019 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.28</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/1012140/000095012311047784/f58570exv10w1wi.htm">Collaboration Agreement, dated April 22, 1994, by and between Bayer Corporation (formerly Miles, Inc.) and Onyx Pharmaceuticals, Inc.</a></span><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(Filed as an exhibit to Form 10-Q for the quarter ended March 31, 2011 by Onyx Pharmaceuticals, Inc. on May 10, 2011 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.29</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="margin-bottom:2pt;margin-top:2pt;text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/1012140/000095014906000261/f20295exv10w1xiy.htm">Amendment to Collaboration Agreement, dated April 24, 1996, by and between Bayer Corporation and Onyx Pharmaceuticals, Inc.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended March 31, 2006 by Onyx Pharmaceuticals, Inc. on May 10, 2006 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.30</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/1012140/000095014906000261/f20295exv10w12.htm">Amendment to Collaboration Agreement, dated February 1, 1999, by and between Bayer Corporation and Onyx Pharmaceuticals, Inc.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended March 31, 2006 by Onyx Pharmaceuticals, Inc. on May 10, 2006 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.31</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/1012140/000119312512081975/d265452dex101v.htm">Settlement Agreement and Release, dated October 11, 2011, by and between Bayer Corporation, Bayer AG, Bayer HealthCare LLC and Bayer Pharma AG and Onyx Pharmaceuticals, Inc.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2011 by Onyx Pharmaceuticals, Inc. on February 27, 2012 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr></table></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="-sec-extract:summary;margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">55</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:40.5pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.415%"><tr><td style="width:1.0%"></td><td style="width:9.635%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:2.005%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:85.960%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.32</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/1012140/000119312512081975/d265452dex101iv.htm">Fourth Amendment to Collaboration Agreement, dated October 11, 2011, by and between Bayer Corporation and Onyx Pharmaceuticals, Inc.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2011 by Onyx Pharmaceuticals, Inc. on February 27, 2012 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.33</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815415000022/amgn-ex1043_2015630xq2.htm">Side Letter Regarding Collaboration Agreement, dated May 29, 2015, by and between Bayer HealthCare LLC and Onyx Pharmaceuticals, Inc.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended June 30, 2015 on August 5, 2015 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.34</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000031/sideletterregardingcol.htm">Side Letter Regarding Collaboration Agreement and Stivarga Agreement, dated February 13, 2020, by and between Onyx Pharmaceuticals, Inc. and Bayer HealthCare LLC.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended March 31, 2020 on May 1, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.35</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815417000009/amgn-exhibit1040_2017033110q.htm">Sourcing and Supply Agreement, dated January 6, 2017, by and between Amgen USA Inc., a wholly owned subsidiary of Amgen Inc., and DaVita Inc.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (portions of the exhibit have been omitted pursuant to a request for confidential treatment). (Filed as an exhibit to Form 10-Q for the quarter ended March 31, 2017 on April 27, 2017 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.36</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815417000021/amgn-ex1041amgenxnovartism.htm">Exclusive License and Collaboration Agreement, dated August 28, 2015, by and between Amgen Inc. and Novartis Pharma AG</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (portions of the exhibit have been omitted pursuant to a request for confidential treatment). (Filed as an exhibit to Form 10-Q for the quarter ended June 30, 2017 on July 26, 2017 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.37</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815417000021/amgn-ex1042amend1tolicense.htm">Amendment No. 1 to the Exclusive License and Collaboration Agreement, dated April 21, 2017, by and between Amgen Inc. and Novartis Pharma AG</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (portions of the exhibit have been omitted pursuant to a request for confidential treatment). (Filed as an exhibit to Form 10-Q for the quarter ended June 30, 2017 on July 26, 2017 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.38</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815417000021/amgn-ex1043amend2tonovarti.htm">Amendment No. 2 to the Exclusive License and Collaboration Agreement, dated April 21, 2017, by and between Amgen Inc. and Novartis Pharma AG</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (portions of the exhibit have been omitted pursuant to a request for confidential treatment). (Filed as an exhibit to Form 10-Q for the quarter ended June 30, 2017 on July 26, 2017 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.39</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:112%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:112%;text-decoration:underline" href="https://www.sec.gov/Archives/edgar/data/318154/000031815421000034/amgn-ex1039_2021630xq2.htm">Amended and Restated Collaboration Agreement, dated June 2, 2021, by and between Amgen Inc. and Novartis Pharma AG</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:112%"> (portions of the exhibit have been omitted because they are both (i) not material and (ii) would be competitively harmful if publicly disclosed). (Filed as an exhibit to Form 10-Q for the quarter ended June 30, 2021 on August 4, 2021 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.40</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000017/a1041bridgecollaborati.htm">Collaboration Agreement, dated October 31, 2019, by and between Amgen Inc. and BeiGene Switzerland GmbH, a wholly-owned subsidiary of BeiGene, Ltd.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (portions of the exhibit have been omitted because they are both (i) not material and (ii) would be competitively harmful if publicly disclosed). (Filed as an exhibit to Form 10-K for the year ended December 31, 2019 on February 12, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.41</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000017/a1042guaranteeagreement.htm">Guarantee, dated as of October 31, 2019, made by and among BeiGene, Ltd. and Amgen Inc.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-K for the year ended December 31, 2019 on February 12, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.42</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312520003926/d848812dex991.htm">Share Purchase Agreement, dated October 31, 2019, by and between Amgen Inc. and BeiGene, Ltd.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (portions of the exhibit have been omitted because they are both (i) not material and (ii) would be competitively harmful if publicly disclosed). (Filed as an exhibit to Schedule 13D on January 8, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.43</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312520003926/d848812dex992.htm">Amendment No. 1 to Share Purchase Agreement, dated December 6, 2019, by and among BeiGene, Ltd. and Amgen Inc.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Schedule 13D on January 8, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.44</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000060/a1046restatedamendment.htm">Restated Amendment No. 2 to Share Purchase Agreement, dated September 24, 2020, by and among BeiGene, Ltd. and Amgen Inc.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (Filed as an exhibit to Form 10-Q for the quarter ended September 30, 2020 on October 29, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.45</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000119312512216282/d312223dex1055.htm">Collaboration Agreement dated March 30, 2012 by and between Amgen Inc. and AstraZeneca Collaboration Ventures, LLC, a wholly owned subsidiary of AstraZeneca Pharmaceuticals LP</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (portions of the exhibit have been omitted pursuant to a request for confidential treatment). (Filed as an exhibit to Form 10-Q for the quarter ended March 31, 2012 on May 8, 2012 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.46</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="https://www.sec.gov/Archives/edgar/data/318154/000031815415000005/amgn-ex1037_20141231x10k.htm">Amendment No. 1 to the Collaboration Agreement, dated October 1, 2014, by and among Amgen Inc., AstraZeneca Collaboration Ventures, LLC and AstraZeneca Pharmaceuticals LP</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (portions of the exhibit have been omitted pursuant to a request for confidential treatment). (Filed as an exhibit to Form 10-K for the year ended December 31, 2014 on February 19, 2015 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr></table></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="-sec-extract:summary;margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">56</span></div></div></div><hr style="page-break-after:always"/><div style="min-height:40.5pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.415%"><tr><td style="width:1.0%"></td><td style="width:9.635%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:2.005%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:85.960%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.47</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815420000048/amgn-ex10492020630xq2.htm">Amendment Nos. 2 through 6 to the March 30, 2012 Collaboration Agreement between Amgen Inc. and AstraZeneca Collaboration Ventures, LLC, dated May 2 and 27 and October 2, 2016, January 31, 2018, and May 15, 2020, respectively</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (portions of the exhibit have been omitted because they are both (i) not material and (ii) would be competitively harmful if publicly disclosed.) (Filed as an exhibit to Form 10-Q for the quarter ended June 30, 2020 on July 29, 2020 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.48</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="http://www.sec.gov/Archives/edgar/data/318154/000031815421000010/amgn-ex1050_20201231xq4.htm">Amendment No. 7 to the Collaboration Agreement, dated December 18, 2020, by and between Amgen Inc. and AstraZeneca Collaboration Ventures, LLC</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (portions of the exhibit have been omitted because they are both (i) not material and (ii) would be competitively harmful if publicly disclosed.) (Filed as an exhibit to Form 10-K for the year ended December 31, 2020 on February 9, 2021 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10.49</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:112%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:112%;text-decoration:underline" href="https://www.sec.gov/Archives/edgar/data/318154/000031815421000034/amgn-ex1049_2021630xq2.htm">License and Collaboration Agreement, dated June 1, 2021, by and between Amgen Inc. and Kyowa Kirin Co., Ltd.</a></span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:112%"> (portions of the exhibit have been omitted because they are both (i) not material and (ii) would be competitively harmful if publicly disclosed). (Filed as an exhibit to Form 10-Q for the quarter ended June 30, 2021 on August 4, 2021 and incorporated herein by reference.)</span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">31*</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="amgn-ex31_2021930xq3.htm">Rule 13a-14(a) Certifications.</a></span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32**</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="text-align:justify"><span style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline"><a style="-sec-extract:exhibit;color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline" href="amgn-ex32_2021930xq3.htm">Section 1350 Certifications.</a></span></div></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">101.INS</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Inline XBRL Instance Document - The instance document does not appear in the interactive data file because its XBRL tags are embedded within the Inline XBRL document.</span></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">101.SCH*</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Inline XBRL Taxonomy Extension Schema Document.</span></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">101.CAL*</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Inline XBRL Taxonomy Extension Calculation Linkbase Document.</span></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">101.DEF*</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Inline XBRL Taxonomy Extension Definition Linkbase Document.</span></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">101.LAB*</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Inline XBRL Taxonomy Extension Label Linkbase Document.</span></td></tr><tr style="height:5pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">101.PRE*</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Inline XBRL Taxonomy Extension Presentation Linkbase Document.</span></td></tr><tr style="height:3pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">104</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101).</span></td></tr></table></div><div style="text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">____________________________</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(* = filed herewith)</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(** = furnished herewith and not &#8220;filed&#8221; for purposes of Section&#160;18 of the Securities Exchange Act of 1934, as amended)</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(+ = management contract or compensatory plan or arrangement)</span></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="-sec-extract:summary;margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">57</span></div></div></div><div id="i0b2dd96150e340208a57faec23ec2da5_130"></div><hr style="page-break-after:always"/><div style="min-height:42.75pt;width:100%"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span><br/></span></div></div><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">SIGNATURES</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this Quarterly Report to be signed on its behalf by the undersigned, thereunto duly authorized.</span></div><div style="margin-bottom:1pt;text-align:justify;text-indent:22.5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.707%"><tr><td style="width:1.0%"></td><td style="width:4.325%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:39.369%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:4.911%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:2.565%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:43.330%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Amgen Inc.</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="9" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(Registrant)</span></td></tr><tr style="height:15pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Date:</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%;text-decoration:underline">November 2, 2021</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">By:</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">/</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">S</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">/&#160;&#160;PETER H. GRIFFITH</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Peter H. Griffith</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Executive Vice President and Chief Financial Officer</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">(Principal Financial Officer)</span></td></tr></table></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="margin-bottom:8pt;text-align:center;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">58</span></div></div></div></body></html>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-2.7
<SEQUENCE>2
<FILENAME>amgn-ex27_202193021xq3.htm
<DESCRIPTION>AGREEMENT AND PLAN OF MERGER WITH TENEOBIO, INC.
<TEXT>
<!DOCTYPE html PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/html4/loose.dtd"><html><head>
<!-- Document created using Wdesk -->
<!-- Copyright 2021 Workiva -->
<title>Document</title></head><body><div id="ie89a4d87abd349778894081552e8cb68_1"></div><div style="min-height:72pt;width:100%"><div style="text-align:right"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">Exhibit 2.7</font></div><div style="text-align:right"><font><br></font></div></div><div style="margin-bottom:24pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY &#91;***&#93;, HAS BEEN OMITTED BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) IS THE TYPE THAT THE REGISTRANT TREATS AS PRIVATE OR CONFIDENTIAL.&#160;&#160;&#160;&#160;</font></div><div style="margin-bottom:24pt;text-align:center"><font><br></font></div><div style="margin-bottom:24pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">AGREEMENT AND PLAN OF MERGER</font></div><div style="margin-bottom:24pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">dated as of July 27, 2021</font></div><div style="margin-bottom:24pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">by and among</font></div><div style="margin-bottom:24pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">AMGEN INC.,</font></div><div style="margin-bottom:24pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">TUXEDO MERGER SUB, INC.,</font></div><div style="margin-bottom:24pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">TENEOBIO, INC.,</font></div><div style="margin-bottom:24pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">and</font></div><div style="margin-bottom:24pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">FORTIS ADVISORS LLC, as the Pre-Closing Holders&#8217; Representative</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">________________________________________________________________________</font></div><div><font><br></font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div><font><br></font></div></div></div><div id="ie89a4d87abd349778894081552e8cb68_4"></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">TABLE OF CONTENTS</font></div><div style="margin-bottom:12pt;text-align:right"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%;text-decoration:underline">Page</font></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:93.300%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:4.500%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Article I. CERTAIN DEFINITIONS</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">2</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 1.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Definitions</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">2</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 1.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Construction</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">23</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 1.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Knowledge</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">23</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Article II. THE MERGER&#59; CLOSING</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">24</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 2.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">The Merger</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">24</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 2.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Effects of the Merger</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">24</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 3.75pt;text-align:left;vertical-align:top"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 2.3&#160;&#160;&#160;&#160;Closing&#59; Effective Time</font></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">24</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 3.77pt;text-align:left;vertical-align:top"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:133%">Section 2.4&#160;&#160;&#160;&#160;Certificate of Incorporation and Bylaws of the Surviving Corporation</font></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">25</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 3.77pt;text-align:left;vertical-align:top"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:133%">Section 2.5&#160;&#160;&#160;&#160;Directors and Officers of the Surviving Corporation</font></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">25</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 3.77pt;text-align:left;vertical-align:top"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:133%">Article III. EFFECTS OF THE MERGER ON THE CAPITAL STOCK AND EQUITY AWARDS</font></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">25</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Conversion of Company Shares&#59; Treatment of Company Options</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">25</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Closing Payments and Exchange of Certificates</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">27</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Estimated Net Working Capital Adjustment Amount&#59; Estimated Closing Date Funded Debt&#59; Estimated Closing Date Cash&#59; Estimated Closing Date Transaction Expenses</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">28</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Adjustment Amount</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">29</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Stockholder Representative Expense Fund</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">31</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.6</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Exchange Agent</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">31</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.7</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Lost Certificate</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">32</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Dissenting Shares</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">32</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.9</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Withholding</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">33</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Milestone Payments</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">33</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.11</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#91;***&#93;</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">36</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.12</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Tax Treatment..</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">36</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Article IV. REPRESENTATIONS AND WARRANTIES OF THE COMPANY</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">36</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Corporate Organization of the Company</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">37</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Subsidiaries</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">37</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Due Authorization</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">38</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Vote Required</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">39</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">No Conflict</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">39</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.6</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Governmental Consents</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">39</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.7</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Capitalization of the Company</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"><a href="#ie89a4d87abd349778894081552e8cb68_7" style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:none">38</a></font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Financial Statements</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">40</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.9</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Undisclosed Liabilities</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">41</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Litigation and Proceedings</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">42</font></div></td></tr></table></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:93.300%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:4.500%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.11</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Compliance with Laws&#59; Governmental Authorities</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">42</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.12</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Contracts&#59; No Defaults</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">44</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.13</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Company Benefit Plans</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">46</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.14</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Employment and Labor Relations</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">49</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.15</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Taxes</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">51</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.16</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Brokers&#8217; Fees</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">53</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.17</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Insurance</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">53</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.18</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Licenses, Permits and Authorizations</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">53</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.19</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Real Property</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">59</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.20</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Intellectual Property</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">59</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.21</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Environmental Matters</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">58</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.22</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Absence of Changes</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">59</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.23</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Affiliate Matters</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">59</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.24</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Books and Records</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">60</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.25</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Certain Business Practices</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">60</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.26</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">No Debarment</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">60</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.27</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Termination of Certain Agreements</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">61</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.28</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Funded Debt</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">61</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.29</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Data Privacy and Security</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">61</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.30</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">No Outside Reliance</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">62</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.31</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">No Additional Representations or Warranties</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">63</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Article V. REPRESENTATIONS AND WARRANTIES OF BUYER AND MERGER SUB</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">63</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 5.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Corporate Organization</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">63</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 5.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Due Authorization</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">63</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 5.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">No Conflict</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">63</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 5.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Governmental Consents</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">64</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 5.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Financial Ability</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">64</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 5.6</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Brokers&#8217; Fees</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">64</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 5.7</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">No Additional Representations or Warranties</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">64</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Article VI. COVENANTS OF THE COMPANY</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">64</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Conduct of Business</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">64</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">No Solicitation</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">68</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Confidentiality&#59; Access</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">69</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Notification of Certain Matters</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">70</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">HSR Act and Antitrust Approvals</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">71</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.6</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Consent of Company Stockholders</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">71</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.7</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Data Room Disk</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">71</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Restructuring</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">72</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Article VII. COVENANTS OF BUYER</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">72</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 7.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">HSR Act and Antitrust Approvals</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">72</font></div></td></tr></table></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">ii</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:93.300%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:4.500%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 7.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Director &#38; Officer Indemnification and Insurance</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">72</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 7.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Employment Matters</font></div></td><td colspan="3" style="padding:2px 1pt 2px 3.75pt;text-align:left;vertical-align:top"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">73</font></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Article VIII. JOINT COVENANTS</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">75</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 8.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Support of Transaction</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">75</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 8.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Escrow Agreement</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">76</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 8.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Stockholder Approval</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">76</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 8.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Further Assurances</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">76</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 8.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Tax Matters</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">76</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 8.6</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">HSR Act and Antitrust Approvals</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">76</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Article IX. CONDITIONS TO OBLIGATIONS</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">80</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 9.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Conditions to the Obligations of Buyer, Merger Sub and the Company</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">80</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 9.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Conditions to the Obligations of Buyer and Merger Sub</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">80</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 9.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Conditions to the Obligations of the Company</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">82</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 9.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Waiver of Conditions&#59; Frustration of Conditions</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">82</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Article X. TERMINATION</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">82</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 10.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Termination</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">83</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 10.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Effect of Termination</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">84</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Article XI. INDEMNIFICATION</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">84</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Survival of Representations and Warranties</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">84</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Indemnification of Buyer</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">84</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Indemnification of Pre-Closing Holders</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">86</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Limits on Indemnification</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">86</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Notice of Loss&#59; Third Party Claims</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">88</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.6</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Tax Treatment</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">89</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.7</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Remedies</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">89</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Set-Off</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">89</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.9</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">No Right of Contribution</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">90</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">No Circular Recovery</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">90</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.11</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Release of Escrow Funds</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">90</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Article XII. STOCKHOLDER REPRESENTATIVE</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">90</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 12.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Designation and Replacement of Stockholder Representative</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">90</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 12.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Authority and Rights of the Stockholder Representative&#59; Limitations on Liability</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">91</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Article XIII. MISCELLANEOUS</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">93</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Waiver</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">93</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Notices</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">93</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Assignment</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">94</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Rights of Third Parties</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">94</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Release</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">94</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.6</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Expenses</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">96</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.7</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Governing Law</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">96</font></div></td></tr></table></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">iii</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"></td><td style="width:93.300%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:4.500%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Captions&#59; Counterparts</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">96</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.9</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Schedules, Exhibits and Annexes</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">96</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Entire Agreement</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">97</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.11</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Amendments</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">97</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.12</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Publicity</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">97</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.13</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Severability</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">97</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.14</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Jurisdiction&#59; Waiver of Jury Trial</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">98</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.15</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Enforcement</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">98</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.16</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Tax Advice</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">99</font></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.17</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:11pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Privilege</font></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:2.75pt;padding-right:2.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">99</font></div></td></tr></table></div><div><font><br></font></div><div style="margin-bottom:12pt"><font><br></font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">iv</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Exhibits</font></div><div style="margin-bottom:12pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Exhibit A &#8211; Form of Written Consent</font></div><div style="margin-bottom:12pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Exhibit B &#8211; Form of Certificate of Merger</font></div><div style="margin-bottom:12pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Exhibit C &#8211; Form of Certificate of Incorporation</font></div><div style="margin-bottom:12pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Exhibit D &#8211; Form of Escrow Agreement</font></div><div style="margin-bottom:12pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Exhibit E &#8211; Forms of Second Amended and Restated Assignment and License Agreements</font></div><div><font><br></font></div><div style="margin-bottom:12pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Annexes</font></div><div style="margin-bottom:12pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Annex A &#8211; TNB-585</font></div><div style="margin-bottom:12pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Annex B &#8211; Pro Forma Payment Spreadsheet</font></div><div style="margin-bottom:12pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Annex C &#8211; </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Eligible Programs</font></div><div style="margin-bottom:12pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Annex D &#8211; Restructuring Step Plan</font></div><div style="margin-bottom:12pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Annex E &#8211; Sample Net Working Capital Statement</font></div><div><font><br></font></div><div><font><br></font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">v</font></div><div><font><br></font></div></div></div><div id="ie89a4d87abd349778894081552e8cb68_7"></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%;text-decoration:underline">AGREEMENT AND PLAN OF MERGER</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">This Agreement and Plan of Merger (this &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Agreement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), dated as of July 27, 2021, is entered into by and among Amgen Inc., a Delaware corporation (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Buyer</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), Tuxedo Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of Buyer (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Merger Sub</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), TeneoBio, Inc., a Delaware corporation (together with its Subsidiaries, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), and Fortis Advisors LLC, a Delaware limited liability company, solely in its capacity as the initial Stockholder Representative hereunder.</font></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">RECITALS</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">WHEREAS, the respective Boards of Directors of Merger Sub and the Company have (a)&#160;unanimously determined that the Merger (defined below) and entry into this Agreement are advisable and fair to, and in the best interest of their respective stockholders, (b) unanimously approved and declared advisable this Agreement and the consummation of the transactions contemplated hereby, including the Merger (defined below) upon the terms and subject to the conditions of this Agreement and in accordance with the Delaware General Corporation Law (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">DGCL</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) and (c) unanimously recommended that their respective stockholders adopt this Agreement&#59;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">WHEREAS, the Board of Directors of Buyer has determined that the Merger and entry into this Agreement is advisable and fair to, and in the best interest of, its stockholders&#59; </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">WHEREAS, within two (2) Business Days after the execution and delivery of this Agreement, the Company shall, in accordance with the DGCL and the California General Corporation Law (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">CGCL</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), the Company Charter and the Company Bylaws, obtain and deliver to Buyer true, correct and complete copies of irrevocable written consents in the form attached hereto as </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Exhibit A</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (each a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Written Consent</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) (i) waiving any appraisal rights under Section 262 of the DGCL and dissenters rights under the CGCL and (ii) adopting this Agreement and approving the Merger, the Restructuring, the other Transaction Documents, and the other transactions contemplated hereby executed by Company Stockholders holding (a) at least a majority of the issued and outstanding shares of Company Capital Stock and (b) at least a majority of the issued and outstanding shares of Series A-2 Preferred Stock (on an as-converted basis) voting together as a single class on an as-converted basis (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Merger Consent</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;)&#59; </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">WHEREAS, prior to the Closing Date and as a condition to the willingness of Buyer to enter into this Agreement, the Company shall have completed the Restructuring in accordance with the terms and conditions of this Agreement and the Restructuring Step Plan&#59; and</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">WHEREAS, for certain limited purposes, and subject to the terms set forth herein, the Stockholder Representative shall serve as a representative of the Pre-Closing Holders.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">NOW, THEREFORE, in consideration of the foregoing and the respective representations, warranties, covenants and agreements set forth in this Agreement and intending to be legally bound hereby, Buyer, Merger Sub and the Company agree as follows&#58;</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">ARTICLE I.<br>CERTAIN DEFINITIONS</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 1.1&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Definitions</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. As used herein, the following terms shall have the following meanings&#58;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">AbbVie</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means AbbVie Inc., a Delaware corporation.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Accounting Standards</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means GAAP.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Acquired Subsidiaries</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 6.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Acquisition Proposal</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, other than the transactions contemplated by this Agreement, any offer, proposal or inquiry relating to, or any Person&#8217;s indication of interest in, (a)&#160;the sale, license, disposition or acquisition of a material portion of the assets of the Company, taken as a whole&#59; (b) the issuance, disposition or acquisition of (i) capital stock or other equity securities of the Company representing at least ten percent (10%) of the outstanding shares of Company Capital Stock&#59; (ii) any subscription, option, call, warrant, preemptive right, right of first refusal or any other right (whether or not exercisable) to acquire capital stock or other equity securities of the Company (other than the grant of Company Options to newly hired employees of the Company in the ordinary course of business consistent with past practices) representing at least ten percent (10%) of the outstanding Company Capital Stock&#59; or (iii) securities, instruments or obligations that are or may become convertible into or exchangeable for capital stock or other equity securities of the Company representing at least ten percent (10%) of the outstanding Company Capital Stock&#59; or (c) any merger, consolidation, business combination, reorganization or similar transaction involving the Company.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Action</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any action, claim, demand, arbitration, hearing, charge, complaint, investigation, audit, examination, indictment, litigation, suit or other civil, criminal, administrative or investigative proceeding (whether at law or in equity, before or by any Governmental Authority).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Adjustment Amount</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(c)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Adjustment Escrow Amount</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means an amount equal to ten million U.S. Dollars ($10,000,000).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Adjustment Escrow Funds</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, at any given time after Closing, the funds remaining in one or more accounts in which the Escrow Agent has deposited the Adjustment Escrow Amount in accordance with the Escrow Agreement, including any amount of interest actually earned.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Advisory Group</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section&#160;12.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Affiliate</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, with respect to any specified Person, any Person that, directly or indirectly, controls, is controlled by, or is under common control with, such specified Person, </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">2</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">through one or more intermediaries or otherwise. For the avoidance of doubt, following the Closing, Affiliates of Buyer shall include the Company and its Subsidiaries.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Aggregate Option Exercise Price</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the aggregate exercise price of all Company Options that are vested prior to, or become vested in connection with, the Closing.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Agreement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in the preamble hereto.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Anti-Corruption Laws</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the U.S. Foreign Corrupt Practices Act, as amended, and any other applicable Laws, rules and regulations concerning or relating to public or commercial bribery or corruption.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Antitrust Authority</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the Antitrust Division of the United States Department of Justice, the United States Federal Trade Commission or the antitrust or competition law authorities of any other jurisdiction (whether the United States, a state within the United States, foreign or multinational).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Antitrust Information or Document Request</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any request or demand for the production, delivery or disclosure of documents or other evidence or information, or any request or demand for the production of witnesses for interviews or depositions or other oral or written testimony, by any Antitrust Authority relating to the transactions contemplated hereby or by any third party challenging the transactions contemplated hereby, including any so called &#8220;second request&#8221; for additional information or documentary material or any civil investigative demand made or issued by the Antitrust Division of the United States Department of Justice or the United States Federal Trade Commission or any subpoena, interrogatory or deposition by any Antitrust Authority.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Antitrust Laws</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.6(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Approved Relatives</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(h)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#91;***&#93;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Assumed Tax Rate</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, with respect to any Tax year, the highest combined Tax rate applicable to corporations for U.S. federal income and California income Tax purposes in effect for such year, taking into account the deductibility of California income Taxes for U.S. federal income Tax purposes to the extent permitted by Law. The Assumed Tax Rate for the current Tax year is 27.9836% under present Law, computed as the corporate U.S. federal income Tax rate of 21%, plus the corporate California income Tax rate of 8.84%, minus the product of the two rates (1.8564%).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Bioinformatics Platform</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the Company&#8217;s proprietary antibody discovery engine comprised of (a) next-generation sequencing of the full repertoire of the immunized UniRat, (b)&#160;bioinformatic B-cell lineage analysis of human variable domain sequences to identify antigen&#160;specific CDR families, and (c) high-throughput gene assembly, expression and functional screens for identifying leads.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">3</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">BLA</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means (a) a Biologics License Application as defined under the Public Health Service Act (42 U.S.C. &#167;&#167; 201 et seq.) and (b)&#160;all supplements and amendments to the foregoing.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Board Recommendation</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.3(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Business</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the business of the Company other than the Excluded Businesses.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Business Day</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any day that is not a Saturday, a Sunday or other day on which the Federal Reserve Bank of New York is closed.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Buyer</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in the preamble hereto.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Buyer Cure Period</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 10.1(c)(i)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Buyer Indemnified Party</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Cancelled Shares</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.1(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">CARES Act</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the Coronavirus Aid, Relief, and Economic Security Act and the regulations promulgated thereunder. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Cash</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; of any Person as of any date means the cash and cash equivalents required to be reflected as cash and cash equivalents on a balance sheet of such Person and its Subsidiaries as of such date prepared in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, but excluding issued but uncleared checks, wires, transfers and drafts, and Restricted Cash.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">CERCLA</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the Federal Comprehensive, Environmental Response, Compensation, and Liability Act of 1980 (42 U.S.C. &#167;&#167; 9601 et seq.) and any foreign and state Law counterparts.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Certificate of Merger</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 2.1(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Certificates</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.2(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">CGCL</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in the Recitals.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Clinical Trial</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(b)(i)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 2.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Date</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 2.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Date Cash</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Date Funded Debt</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Date Net Working Capital</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">4</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Date Transaction Expenses</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Merger Consideration</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.1(c)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Option Consideration</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.1(f)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Working Capital Statement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Code</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the United States Internal Revenue Code of 1986, as amended.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Common Share</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.1(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Common Stock</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the common stock, par value $0.0001 per share, of the Company.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in the preamble hereto.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Balance Sheet Date</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Benefit Plans</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means (a) each &#8220;employee benefit plan&#8221; (as such term is defined in Section&#160;3(3) of ERISA or any similar plan subject to laws of a jurisdiction outside of the United States), (b) each employment, consulting, advisor or other service agreement or arrangement, (c)&#160;each noncompetition, nondisclosure, nonsolicitation, severance, termination, pension, retirement, supplemental retirement, excess benefit, profit sharing, bonus, incentive, deferred compensation, retention, transaction, change in control and similar plan, program, arrangement, agreement, policy or commitment, (d) each compensatory stock option, restricted stock, performance stock, stock appreciation, deferred stock or other equity or equity-based plan, program, arrangement, agreement, policy or commitment, (e) each savings, life, health, disability, accident, medical, dental, vision, cafeteria, insurance, flex spending, adoption&#47;dependent&#47;employee assistance, tuition, vacation, paid-time-off, other welfare fringe benefit and each other employee benefit plan, program or arrangement maintained, sponsored or contributed to by the Company or any of its Subsidiaries or under which of the Company of its Subsidiaries has any obligation or liability, whether actual or contingent, direct or indirect, to provide compensation or benefits to or for the benefit of any of its current or former employees, consultants, managers or directors, or the spouses, beneficiaries or other dependents thereof (other than any statutory plan, program or arrangement that is required under applicable law, other than the laws of the United States, and maintained by any Governmental Authority).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Bylaws</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the bylaws of the Company, as amended.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Capital Stock</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the Common Stock and the Preferred Stock.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Charter</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the Restated Certificate of Incorporation of the Company dated August 24, 2020, as amended.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Cure Period</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 10.1(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">5</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Equity Plan</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the Company&#8217;s 2011 Stock Option and Grant Plan, as amended from time to time.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Intellectual Property</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">the Owned Intellectual Property Rights and the Licensed Intellectual Property Rights</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Option</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.1(f).</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Product</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means each product candidate included in the Eligible Programs. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Regulatory Filings</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.11(c)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Stockholder</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means those Persons who held shares of outstanding Company Capital Stock immediately prior to the Effective Time (not inclusive of holders of Company Options).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Confidentiality Agreement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 13.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Constituent Corporations</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 2.1(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Continuing Employees</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 7.3(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Contracts</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any loan or credit agreement, bond, debenture, note, mortgage, indenture, guarantee, security agreement, lease or other contract, commitment, agreement, instrument, obligation, undertaking, concession, franchise, license, evidence of indebtedness or legally binding arrangement or understanding, whether written or oral.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">COVID-19</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means SARS-CoV-2 or COVID-19 and any evolutions thereof or related or associated epidemics, pandemics or disease outbreaks.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Deferred Payroll Taxes</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any Taxes payable by the Company or any Subsidiary that (a) relate to the portion of the &#8220;payroll tax deferral period&#8221; (as defined in Section 2302(d) of the CARES Act) that occurs prior to the Closing and (b) are payable following the Closing as permitted by Section 2302(a) of the CARES Act, calculated without giving effect to any tax credits afforded under the CARES Act, the Families First Coronavirus Response Act or any similar applicable federal, state or local Law to reduce the amount of any such Taxes payable or owed.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Deficit Amount</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(d)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Determination Date</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">DGCL</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in the Recitals.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Disclosure Schedules</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in the first sentence of </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article&#160;IV</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Dissenting Shares</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.1(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">6</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Dissenting Stockholders</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.1(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">DOJ</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the United Stated Department of Justice or any subdivision or successor thereto. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Effective Time</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 2.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Eligible Program</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(b)(ii)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Environmental Laws</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any and all applicable foreign, federal, state or local Law relating to (a) the manufacture, processing, use, labeling, distribution, treatment, storage, discharge, disposal, recycling, generation or transportation of Hazardous Materials, (b) pollution of the environment, including but not limited to air (including indoor air), soil, surface, subsurface, groundwater or noise pollution, (c) Releases or threatened Releases, (d) protection of wildlife, endangered species, wetlands or natural resources, (e) underground storage tanks, (f)&#160;above-ground storage tanks, (g) health and safety of employees and other persons, (h)&#160;the presence or content of Hazardous Materials in a product, item or article, whether a component or finished product, (i) product life-cycle requirements, (j) land use and zoning requirements, and (k)&#160;notification requirements relating to the foregoing. Without limiting the above, Environmental Law also includes the following within the U.S. and all foreign equivalents thereof&#58; (A) CERCLA, (B) the Solid Waste Disposal Act, (C) the Emergency Planning and Community Right to Know Act of 1986 (42 U.S.C. &#167;&#167; I 101 et seq.), (D) the Clean Air Act (42 U.S.C. &#167;&#167; 7401 et seq.), (E)&#160;the Clean Water Act (33 U.S.C. &#167;&#167; 1251 et seq.), (F) the Toxic Substances Control Act (15 U.S.C. &#167;&#167; 2601 et seq.), (G) the Hazardous Materials Transportation Act (49 U.S.C. &#167;&#167; 1801 et seq.), (H) the Federal Insecticide, Fungicide and Rodenticide Act (7 U.S.C. &#167;&#167; 136 et seq.), (I) the Federal Safe Drinking Water Act (42 U.S.C. &#167;&#167; 300 et seq.), (J) the Federal Radon and Indoor Air Quality Research Act (42 U.S.C. &#167;&#167; 7401 note, et seq.), (K) the Occupational Safety and Health Act (29 U.S.C. &#167;&#167; 651 et seq.) and (L) any Laws similar or analogous to (including counterparts of) any of the statutes listed above in effect as of the Closing Date.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Equity Interest</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, with respect to any Person, (a) any capital stock, partnership or membership interest, unit of participation or other similar interest (however designated) in such Person and (b) any option, warrant, purchase right, conversion right, exchange right, equity appreciation right, profits interest or phantom stock or equity right or other Contract which would entitle any other Person to acquire any such interest in such Person. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">ERISA</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the Employee Retirement Income Security Act of 1974, as amended.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">ERISA Affiliate</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; of the Company or any of its Subsidiaries any shall mean any entity (whether or not incorporated) that, together with the Company or its Subsidiary, is required to be treated as a single employer under Section 414(b), (c), (m) or (o) of the Code.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Escrow Agent</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.2(d)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Escrow Agreement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">7</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Escrow Amount</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means an amount equal to the sum of the Adjustment Escrow Amount and the Indemnification Escrow Amount.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Escrow Funds</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, at any given time after Closing, the funds remaining in one or more accounts in which the Escrow Agent has deposited the Escrow Amount in accordance with the Escrow Agreement, including any amount of interest actually earned.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Estimated Closing Date Cash</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Estimated Closing Date Funded Debt</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Estimated Closing Date Net Working Capital</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Estimated Closing Date Transaction Expenses</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Estimated Net Working Capital Adjustment Amount</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the amount, which may be positive or negative, equal to (a) Estimated Closing Date Net Working Capital, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">minus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (b)&#160;the Target Closing Date Net Working Capital.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Exchange Agent</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.2(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Excluded Businesses</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the TeneoOne Business, TeneoTwo Business, TeneoFour Business, and TeneoTen Business.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Excluded Employee Liabilities</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any employment, labor, compensation, pension, wage withholding Taxes, employer payroll, social security and similar Taxes, employee welfare and employee benefits related Liabilities, commitments, claims and losses to the extent arising from services provided to any Excluded Entity or an Affiliate of any such Excluded Entity or by service providers directly employed or engaged by any Excluded Entity or an Affiliate of any such Excluded Entity (including each such Person whose employment or service is transferred to an Excluded Entity prior to or as of the Closing and further including any dependent or beneficiary of any such service provider) following the date such service provider&#8217;s employment or other service relationship is transferred to such Excluded Entity or an Affiliate of any such Excluded Entity.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Excluded Entities</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means TeneoOne, TeneoTwo, TeneoFour and TeneoTen.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Excluded Entity Licenses</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.20(k)</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">FDA</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the United States Food and Drug Administration.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">FDCA</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the United States Federal Food, Drug, and Cosmetic Act, as amended, and the regulations promulgated thereunder.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Final Merger Consideration</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.1(c)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Financial Statements</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">8</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">First Phase I Clinical Candidate</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(a)(iii)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Fourth Phase I Clinical Candidate</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(a)(vi)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">FTC</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the United States Federal Trade Commission or any subdivision or successor thereto. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Fundamental Representations</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the representations and warranties contained in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (Corporate Organization of the Company), </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (Subsidiaries), </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (Due Authorization), </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (Vote Required), </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (No Conflict), </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.6</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (Governmental Consents), </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.7</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (Capitalization of the Company), </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.15</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (Taxes), and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.16</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (Brokers&#8217; Fees).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Funded Debt</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; of any Person as of any date means, without duplication (a)&#160;all indebtedness of such Person and its consolidated Subsidiaries for borrowed money, together with accrued and unpaid interest thereon, (b) all obligations issued, undertaken or assumed as the deferred purchase price of property or services (other than trade payables entered into in the ordinary course of business), (c) all reimbursement or payment obligations with respect to letters of credit, surety bonds and other similar instruments (other than undrawn letters of credit and reimbursement obligations in respect of undrawn letters of credit), (d) all obligations evidenced by notes, bonds, debentures or similar instruments, including obligations so evidenced incurred in connection with the acquisition of property, assets or businesses, (e) all indebtedness created or arising under any conditional sale or other title retention agreement, or incurred as financing, in either case with respect to any property or assets acquired with the proceeds of such indebtedness (even though the rights and remedies of the seller or bank under such agreement in the event of default are limited to repossession or sale of such property), (f)&#160;all monetary obligations under any leasing or similar arrangement, (g) any Deferred Payroll Taxes to the extent unpaid as of the Closing, (h)&#160;any unpaid Pre-Closing Taxes, (i)&#160;all deferred revenue, (j) all indebtedness referred to in clauses (a) through (i) above secured by (or for which the holder of such Funded Debt has an existing right, contingent or otherwise, to be secured by) any mortgage, lien, pledge, charge, security interest or other Lien upon or in any property or assets owned by any Person, even though the Person which owns such assets or property has not assumed or become liable for the payment of such indebtedness, (k) the aggregate amount of all prepayment premiums, penalties, breakage costs, &#8220;make whole amounts,&#8221; costs, expenses and other payment obligations of such Person that would arise (whether or not then due and payable) if any such items under clauses (a) through (j) above were prepaid, extinguished, unwound or settled, and (l) all contingent obligations in respect of indebtedness or obligations of others of the kinds referred to in clauses (a) through (k) above.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Funding Amount</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.2(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">GAAP</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the generally accepted accounting principles in the United States, consistently applied.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Good Clinical Practice</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.11(f)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">9</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Good Laboratory Practice</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.11(e)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Good Manufacturing Practice</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.11(g)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Governmental Authority</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means (a) any nation or government, including any foreign or domestic federal, state, provincial, or local municipality, principality, commonwealth, province, territory, locality, county, prefect, district or other jurisdiction of any nature or other political subdivision or instrumentality thereof&#59; (b) any department, commission, committee, panel, bureau, agency, authority, board, court, official or officer, self-regulatory authority, or other entity or body, domestic or foreign, exercising executive, judicial, regulatory, administrative, enforcement, judicial, police, military, or taxing governmental functions, or (c)&#160;any quasi-governmental, private body or arbitral body exercising any executive, legislative, judicial, quasi-judicial, regulatory, taxing, importing, administrative or other governmental or quasi-governmental authority. For avoidance of doubt, the FDA is considered a Governmental Authority.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Governmental Order</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any order, judgment, ruling, injunction, decree, writ, stipulation, determination or award, in each case, entered by or with any Governmental Authority.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Hazardous Material</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any chemical, pollutant, contaminant, pesticide, fungicide, rodenticide, poison, petroleum or petroleum product, radioactive substance, biological material, genetically modified organism, wastes (including solid, hazardous, extremely hazardous, biohazardous, special, dangerous, or toxic), substance, or material controlled, regulated, listed, limited or defined under any Environmental Law as hazardous, dangerous, or toxic (or words of similar meaning and effect), including&#58; (a) any by-products, derivatives, or combinations of such material, (b) lead, asbestos, asbestos-containing material, presumed asbestos-containing material, poly-chlorinated biphenyls, solvents and waste oil, and mold or other indoor air contaminants, (c)&#160;any &#8220;hazardous substance,&#8221; &#8220;pollutant,&#8221; &#8220;toxic pollutant&#8221; or &#8220;contaminant&#8221; as defined under Environmental Laws, (d) any &#8220;hazardous waste&#8221; as defined under RCRA, or any Environmental Law applicable to the management of waste and (e) any other substance which may be subject of regulatory action by any Governmental Authority in connection with any Environmental Law.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Health Care Laws</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the laws, statutes, codes, and regulations of all Governmental Authorities relating to (i) the research, investigation, development, quality, testing, safety, efficacy, approval, manufacturing, production, holding, preparation, propagation, compounding, conversion, pricing, marketing, promotion, sale, distribution, import, export, coverage, or reimbursement of a drug, device, biological or other medical item, supply or service&#59; (ii) Good Laboratory Practices, Good Clinical Practices, and Good Manufacturing Practices&#59;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(iii) investigational use&#59; (iv)&#160;manufacturing facilities compliance&#59; (v) with respect to pharmaceutical products, safety surveillance, mandated reporting of incidents, occurrences, diseases and events record keeping and filing of required reports with the applicable Governmental Authority&#59; (vi) the import into, or export out of, the U.S. of drugs and materials and technology related to pharmaceutical products&#59; (vii) protection against biosafety risk&#59; (viii) the oversight of pharmaceutical or other interventional or noninterventional research studies, including medical and research record retention&#59; and (x) human and animal subjects protection in research, </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">10</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">including, to the extent applicable, the FDCA (</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">U.S.C. &#167;&#167; 301 et seq.)</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">the Public Health Service Act (42 U.S.C. &#167;&#167; 201 et seq.), </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">each as amended and the applicable regulations promulgated thereunder.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Healthcare Community</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means Healthcare Professionals, Healthcare Institutions, Members of the Scientific Community, Payors, Purchasers, Healthcare Professional Societies and Trade Associations, Patients, and Patient Advocacy Groups. Additionally, the capitalized terms used in the above definition are defined as follows&#58;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Healthcare Professional</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any person licensed to prescribe Buyer&#8217;s products, as well as anyone working for a person licensed to prescribe Buyer&#8217;s products and&#47;or in a position to influence a purchasing decision, including without limitation physicians and other providers (e.g., nurses, pharmacists), dialysis providers, and other office personnel.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Healthcare Institution</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means a facility that provides health maintenance, or treats illness and injury, and can include without limitation any hospital, convalescent hospital, dialysis center, health clinic, nursing home, extended care facility, or other institution devoted to the care of sick, infirm, or aged persons, and is in a position to purchase or influence a purchasing decision for any Buyer product or service.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Members of the Scientific Community</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any scientist, researcher, professor of science and&#47;or medicine, educator, student, research collaborator, intern, laboratory technician, and university or college, as well as any individual employed by such entities.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Payor</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means an organization, including without limitation its directors, officers, employees, contractors and agents, whether private or governmental (e.g., Centers for Medicare and Medicaid Services, Veterans Administration), that provides medical and&#47;or pharmacy plans for covering and reimbursing patients and&#47;or Healthcare Professionals from medical expenses incurred, including without limitation managed care organizations, pharmacy benefit managers, health maintenance organizations, other healthcare coverage providers, and any similar such organization.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Purchaser</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means an individual or entity, including without limitation wholesalers, pharmacies, and group purchasing organizations, that purchase Buyer&#8217;s products to sell to members of the Healthcare Community or that are authorized to act as a purchasing agent for a group of individuals or entities who furnish healthcare services.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(f)&#160;&#160;&#160;&#160;&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Healthcare Industry Professional Society and Trade Association</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means a nonprofit or tax exempt healthcare industry organization seeking to further a particular profession, the interests of individuals engaged in that profession, or the public interest (examples of such include without limitation the American Society of Hematology, the North American Society for Dialysis and Transplantation, the American Society of Hypertension, the American Cancer Society and the American Society of Clinical Oncology).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(g)&#160;&#160;&#160;&#160;&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Patient</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means an individual awaiting or under medical care or treatment, in an area of interest for Buyer. </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">11</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(h)&#160;&#160;&#160;&#160;&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Patient Advocacy Group</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means an organization that advocates for and advances the needs of patients and&#47;or caregivers with respect to one or more therapeutic area(s) or disease state(s).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">HSR Act</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended, and the rules and regulations promulgated thereunder.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">IND</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(b)(iii)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Indemnification Escrow Amount</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means an amount equal to seventy million U.S. Dollars ($70,000,000).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Indemnified Party</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the Buyer Indemnified Parties or the Pre-Closing Holder Indemnified Parties, as applicable.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Indemnifying Party</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any Person against whom a claim for indemnification is being asserted under any provision of </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article XI</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Independent Auditor</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#91;***&#93;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Intellectual Property Rights</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any and all intellectual property rights throughout the world, including any and all United States, international and&#47;or foreign or other territorial or regional rights in, arising out of or associated with any of the following&#58; (a) all patents and applications therefor, including all related provisionals, continuations, continuations-in-part, divisionals, reissues, renewals and extensions (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Patents</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), (b)&#160;all inventions (whether patentable or not), invention disclosures, improvements, know-how (including recipes, specifications, formulae, manufacturing and other processes, operating procedures, methods, techniques and all research and development information), proprietary information, trade secrets, works of authorship and other intellectual property, ideas, technology, processes, assays, sketches, schematics, techniques, drawings, designs, descriptions, specifications, and technical documentation, (c) information relating to physical, chemical or biological materials and compounds (including reagents, gene sequences, nucleic acids, amino acids, cell lines, media, antibodies, antibody fragments, compounds, cDNAs, antisense nucleotides, proteins, peptides and vectors), their structures, compositions, and formulations, and methods for their handling, use, and manufacture, and processes, apparatus, and models relating thereto, (d) all copyrights, copyrightable works, copyright registrations and applications therefor, including all rights of authorship, use, publication, publicity, reproduction, distribution, performance and transformation (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Copyrights</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), (e) all industrial designs and any registrations and applications therefor, (f) all domain names, uniform resource locators and other names and locators associated with the internet (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Domain Names</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;),</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and all </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">social media accounts and other handles and app registrations, (g) all trade names, logos, common law trademarks and service marks, trademark and service mark registrations and applications therefor and all goodwill associated therewith (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Trademarks</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), (h) all databases and data collections, (i) all moral and economic rights of authors and inventors, however denominated, (j) all rights in computer software (including </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">12</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">source code, object code, firmware, algorithms, operating systems and specifications) and related technology, (k) all rights in content (including text, graphics, images, audio, video and data) and computer software included on or used to operate and maintain any websites, including all data, documentation, files, cgi and other scripts, all programming code (source and object), subscriber and other data, archives, and server and traffic logs relating to such sites, (l)&#160;all rights of publicity or privacy, including with respect to name, likeness or persona, and (m)&#160;all rights to sue or recover and retain damages and costs and attorneys&#8217; fees for the past, present or future infringement, dilution, misappropriation, or other violation of any of the foregoing anywhere in the world.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Interim Financial Statements</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">International Trade Laws</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means all applicable import, export, reexport, and foreign trade control Laws, statutes, regulations, enactments, directives, and ordinances of any Governmental Authority with jurisdiction over any operations or activities of a party under this Agreement then in effect.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Investment Agreements</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; shall mean (i) all agreements relating to the Equity Interests of the Company and its Subsidiaries and (ii) each of the agreements listed on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule&#160;1.1(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, each as may be amended or amended and restated from time to time.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">IRS</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the United States Internal Revenue Service.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">IT Assets</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any and all computers, computer software, firmware, middleware, servers, workstations, routers, hubs, switches, data communications lines, and all other information technology assets, including all associated documentation related to any of the foregoing, owned by the Company or its Subsidiaries or licensed or leased to the Company or its Subsidiaries.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Law</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any federal, state, territorial, foreign, international, multinational or supranational or local law, common law, statute, ordinance, judicial decision, rule, regulation, agency requirement or other legal requirement, license, treaty, ruling, Governmental Order or permit, directive or code of any Governmental Authority or decisions having the force of law in any jurisdiction from time to time, including Health Care Laws.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Leased Real Property</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means all real property leased, used, or otherwise occupied by the Company.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Letter of Transmittal</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.2(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Liability</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any direct or indirect liability, Loss, Tax, interest obligation, deficiency, judgement, assessment, fine, fee, penalty, expense, Funded Debt, obligation, commitment, expense, claim, deficiency, guaranty or endorsement of or by any Person of any type, known or unknown, and whether accrued or fixed, absolute or contingent, matured or unmatured, determined or determinable, or other, including &#8220;off-balance sheet&#8221; liabilities and </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">13</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">those arising under any Law, Action or judgment and those arising under any contract, agreement, arrangement, commitment or undertaking.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Licensed Intellectual Property Rights</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any and all Intellectual Property Rights owned by a third party and licensed or sublicensed (or purported to be licensed or sublicensed) to the Company or any of its Subsidiaries. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Lien</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any mortgage, deed of trust, pledge, lease, adverse claim, levy, charge, hypothecation, encumbrance, security interest or other lien or restriction of any kind whether arising by Contract or by operation of Law, or any conditional sale Contract, title retention Contract or other Contract to grant any of the foregoing.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Listed Contract</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.12(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Losses</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any and all claims, judgments, actions, causes of action, losses, Governmental Orders, Taxes, fines, amounts paid in settlement, costs (including the costs of defense and enforcement of this Agreement), liabilities, fees, interest obligations, deficiencies or damages (including punitive, exemplary, special, incidental or consequential damages </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> that either (x) any such punitive, exemplary, special, incidental, or consequential damages are actually awarded to a third party by a Governmental Authority or (y) in the case of special, incidental or consequential damages only, any such special or consequential damages are reasonably foreseeable, including reasonable attorneys&#8217; fees and experts&#8217; fees and expenses (whether incurred in connection with a first-party claim or action (including a claim or action for indemnity hereunder), a Third Party Claim or otherwise), expenses.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Majority Holders</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 12.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Material Adverse Effect</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, with respect to the Company and its Subsidiaries, any event, change, circumstance, effect, development or state of facts (whether specific to the applicable party or generally applicable to multiple parties), that has, or would, individually or in the aggregate with other events, reasonably be expected to have or give rise to, a material adverse effect on or material adverse change to (a) the financial condition, business, results of operations, assets or Liabilities, of the Company and its Subsidiaries, taken as a whole, or (b) the ability of the Company to consummate the transactions contemplated hereby or to perform any of its material obligations under this Agreement&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that in no event will any of the following be deemed to constitute a &#8220;Material Adverse Effect&#8221; on or in respect of the Company&#58; (i)&#160;changes in general United States or global business, industry or economic conditions, (ii)&#160;general changes in national or international political or social conditions, including the engagement by the United States or another government in hostilities, whether or not pursuant to the declaration of a national emergency or war, or the occurrence of any military or terrorist attack, (iii)&#160;changes in GAAP (or interpretations thereof), (iv)&#160;changes in Laws (or interpretations thereof), (v)&#160;natural disasters, weather conditions, epidemics or pandemics, including the impacts from COVID-19 and measures taken in response to COVID-19, or other force majeure events, including any material worsening of such conditions threatened or existing as of the date of this Agreement, (vi) changes directly resulting from the execution, announcement or pendency of any of the transactions contemplated by this Agreement, (vii) any </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">14</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">action taken that Buyer has expressly consented to or requested in writing, or (viii) any failure to meet financial projections, estimates or forecasts for any period (it being understood and agreed that the exception in this clause (viii) shall not preclude any party from asserting that the facts giving rise to such failure should be taken into account in determining whether there has been a Material Adverse Effect)&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that with respect to subclauses (i), (ii), (iii), (iv) and (v), above, such event, fact, change, development, circumstance or effect does not have a disproportionate effect on the Company and its Subsidiaries, taken as a whole, as compared to other companies that conduct business in the industries in which the Company and its Subsidiaries conduct business. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Material Claims</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.4(e)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Merger</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 2.1(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Merger Consent</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in the Recitals.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Merger Sub</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in the preamble hereto.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Milestone Achievement Efforts</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(e)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:7.8pt;font-weight:400;line-height:120%;position:relative;top:-4.2pt;vertical-align:baseline"> </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Milestone Obligor</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means Buyer, its Affiliates (including the Surviving Corporation) or any licensee or sublicensee thereof.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Milestone Payment</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Milestone Payment Amount</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(b)(v)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Milestone Report</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Milestones</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(a)(xviii)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Net Working Capital</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; as of any date means an amount equal to (a) the current assets of the Company as of such date (excluding Cash, and deferred and non-deferred Tax assets), </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">minus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (b) the current liabilities of the Company as of such date (excluding Funded Debt and any other deferred and non-deferred Tax liabilities), in each case, as calculated in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. A sample net working capital statement calculating the Net Working Capital as of June 30, 2021 (and containing reasonable detail regarding the Accounting Principles) is set forth on Annex E (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Sample Working Capital Statement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">New Target</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(b)(vi)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Non T-Cell Engager Platform</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the antibody engineering capability platform that generates multi-specific antibodies that contain a tumor antigen binding region and a signal through (a) a co-stimulatory receptor such as CD137 or (b) a cytokine receptor such as IL-2R.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">OmniClic&#8482; Platform</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means &#91;***&#93;.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">15</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">OmniFlic&#174; Platform</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means &#91;***&#93;.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Open Source Software</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any software, libraries or other code (in source or object code form) that is subject to (a)&#160;a license or other agreement commonly referred to as an open source, free software, copyleft or community source code license (including but not limited to any code or library licensed under the GNU Affero General Public License, GNU General Public License, GNU Lesser General Public License, BSD License, Apache Software License, MIT License or any other public source code license arrangement), (b)&#160;any other license or other agreement that requires, as a condition of the use, modification or distribution of software subject to such license or agreement, that such software or other software linked with, called by, combined or distributed with such software be (1)&#160;disclosed, distributed, made available, offered, licensed or delivered in source code form, (2)&#160;licensed for the purpose of making modifications or derivative works, (3)&#160;licensed under terms that allow reverse engineering, reverse assembly, decompiling or disassembly of any kind, or (4)&#160;redistributable or otherwise made available at no charge or (c)&#160;any other license defined as an open source license by the Open Source Initiative as set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">www.opensource.org</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or other &#8220;free software&#8221; or similar licensing or distribution terms.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Option Consideration</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.1(f)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Outside Date</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 10.1(b)(ii)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Owned Intellectual Property Rights</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%"> </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">means any and all Intellectual Property Rights owned or purported to be owned by the Company or any of its Subsidiaries.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Parachute Payment Waiver</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, with respect to any Person, a written agreement waiving such Person&#8217;s right to receive any &#8220;parachute payments&#8221; (within the meaning of Section 280G of the Code and the Department of Treasury regulations promulgated thereunder) solely to the extent required to avoid the imposition of a tax by virtue of the operation of Section 280G of the Code and to accept in substitution therefor the right to receive such payments only if approved by the shareholders of the Company in a manner that complies with Section 280G(b)(5)(B) of the Code and the regulations promulgated thereunder.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Payment Spreadsheet</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.1(d)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pending Claim Reserve</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.11(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Permits</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.18</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Permitted Liens</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means (a) mechanics, materialmen&#8217;s and similar Liens with respect to any amounts not yet due and payable, (b) Liens for Taxes not yet due and payable or which are being contested in good faith through (if then appropriate) appropriate proceedings and for which an adequate reserve has been established in accordance with the Accounting Standards on the Financial Statements, (c) Liens securing rental payments under capital lease agreements, (d)&#160;other Liens arising in the ordinary course of business and not incurred in connection with the borrowing of money and not having a material effect on the use, value or marketability of the </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">16</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">asset subject thereto, (e) Liens referred to in the Financial Statements, and (f) Liens described on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 1.1(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Person</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any individual, firm, corporation, partnership, limited liability company, incorporated or unincorporated association, joint venture, joint stock company, governmental agency or instrumentality or other entity of any kind.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Personal Data</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means information and data concerning, related to or capable of being used to identify, contact or locate a natural Person, device or household, including&#58; (a) the Person&#8217;s name, street address, telephone number, email address, photograph, payment information, social security number, driver&#8217;s license number, passport number, customer or account number, or any other information that relates to or could be used to identify, contact or precisely locate such natural Person, devise or household, and (b) that is &#8220;personal information,&#8221; &#8220;personal data,&#8221; &#8220;personally identifiable information&#8221; or similar term under any Law. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#91;***&#93;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Preclinical Company Milestone Candidate</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section&#160;3.10(b)(viii)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Holder Indemnified Party</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Holder Released Claims</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 13.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Holder Releasees</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 13.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Holder Releasor</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 13.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Holders</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means all Persons who hold one or more Common Shares, Preferred Shares or Company Options immediately prior to the Effective Time.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Period</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 6.1(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Taxes</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, collectively, (a) any Taxes of, imposed on or imposed with respect to, the Company or any of its Subsidiaries for any Pre-Closing Tax Period&#59; (b) any Taxes of the Company or its Subsidiaries arising as a result of Sections 951 or 951A of the Code, in each case attributable to a Pre-Closing Tax Period or the portion of a Straddle Period ending on the Closing Date, determined as though the Tax year of Subsidiary of the Company that is a controlled foreign corporation within the meaning of Section 957 of the Code ended on the Closing Date and any inclusions under Section 951 or 951A of the Code with respect to such Subsidiary were reflected in the Company&#8217;s Pre-Closing Tax Period Tax Returns&#59; (c) any Taxes of the Pre-Closing Holders for any Tax period&#59; (d) any Transfer Taxes payable by the Pre-Closing Holders pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.5(f)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#59; (e) any Taxes attributable to any restructuring or reorganization undertaken by the Company and its Subsidiaries prior to the Closing, including the Restructuring&#59; and (f) any Taxes imposed on, allocated or attributable to or incurred or payable by third parties with respect to which the Company or any of its Subsidiaries has an </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">17</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">obligation to indemnify such third party pursuant to a transaction consummated on or prior to the Closing.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Tax Period</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any Tax period ending on or before the Closing Date and that portion of any Straddle Period ending on (and including) the Closing Date.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Working Capital Statement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Preferred Share</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.1(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Preferred Stock</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, collectively, the Series A-1 Preferred Stock and the Series A-2 Preferred Stock. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Privacy Laws</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any and all applicable Laws, guidelines and codes of conduct governing the privacy, collection, processing, use, transfer, disclosure, protection, integrity and security of Personal Data, data security&#59; data breach&#59; data breach notification&#59; data protection&#59; consumer protection&#59; the requirements for website and mobile application privacy policies and practices&#59; profiling and tracking&#59; advertising and marketing&#59; and email, messaging and&#47;or telemarketing, including&#58; (a) domestic federal and state information privacy laws, including the Federal Trade Commission Act, Health Insurance Portability and Accountability Act (and other state equivalents), regulations by the Office for Human Research Protections, the U.S. Department of Health and Human Services, the Controlling the Assault of Non-Solicited Pornography And Marketing Act, the Telephone Consumer Protection Act and California Consumer Privacy Act (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">CCPA</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;)&#59; (b)&#160;applicable EU &#47; UK information privacy laws, including the General Data Protection Regulation 2016&#47;679, the UK Data Protection the UK Data Protection Act 2018, the UK General Data Protection Regulation as defined by the UK DPA as amended by the Data Protection, Privacy and Electronic Communications (Amendments etc.) (EU Exit) Regulations 2019, and the Privacy and Electronic Communications Regulations 2003, and Directive 2002&#47;58&#47;EC concerning the processing of personal data and the protection of privacy in the electronic communications sector (and any national legislation that implements it)&#59; and (c)&#160;applicable industry frameworks such as the Payment Card Industry Data security Standards, in each case as applicable and in force from time to time, and as amended, consolidated, reenacted or replaced from time to time, and all other similar international, federal, state, provincial, and local Laws, as applicable.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pro Forma Payment Spreadsheet</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.1(d)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pro-Rata Percentage</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, with respect to any Pre-Closing Holder, a ratio (expressed as a percentage) equal to (a) the aggregate consideration payable to such holder under this Agreement, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">divided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">by</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (b) the total consideration, as set forth in the Payment Spreadsheet.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Product Data</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.11(d)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Product Platform(s)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the TCE Platform, the Non T-Cell Engager Platform, the OmniClic&#8482; Platform, the OmniFlic&#174; Platform, the UniRat&#8482; Platform, the Bioinformatics Platform.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">18</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Property Taxes</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means all real property Taxes, personal property Taxes and similar ad valorem Taxes.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">RCRA</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the Resource Conservation and Recovery Act (42 U.S.C. &#167;&#167; 6901 et seq.), and any foreign and state law counterparts.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#91;***&#93;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Regulated Product</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.11(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Regulatory Approval</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means all approvals of the applicable Regulatory Authority(ies) necessary for the marketing and sale of a pharmaceutical product in a country.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Regulatory Authority</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any applicable Governmental Authority responsible for granting approvals for the development, manufacture or commercialization (including Pricing Approvals) of pharmaceutical products in the relevant jurisdiction.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Related Person</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.23</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Release</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any spill, discharge, leak, migration, emission, escape, injection, dumping, disposal, seepage, pumping, pouring, emptying, leaching, abandonment, or other release of any Hazardous Material from any source into the indoor or outdoor environment, whether or not intentional, and whether or not notification or reporting to any Governmental Authority was or is required at the time it initially occurred or continued to occur. Without limiting the above, Release includes the meaning of &#8220;Release&#8221; as defined under CERCLA or any other Environmental Law.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Remedies Exception</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.3(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Required Third Party Consents</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; shall mean the consents and approvals listed in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 1.1(c)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Requisite Stockholder Approval</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 9.2(i)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Restricted Cash</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means security deposits, escrows, legal retainers, supplier cash deposits or other similar amounts.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Restructuring Step Plan</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the transaction structure plan attached as </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Annex D</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> hereto. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Second Amended and Restated License Agreements</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means (i) that certain Second Amended and Restated Asset Assignment and License Agreement, by and between TeneoTwo and the Company, (ii) that certain Second Amended and Restated Asset Assignment and License Agreement, by and between TeneoFour and the Company, and (iii) that certain Amended and Restated Asset Assignment and License Agreement, by and between TeneoTen and the Company, in each case substantially in the forms attached as </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Exhibit E</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> hereto. </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">19</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Second Phase I Clinical Candidate</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(a)(iv)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 1542</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 13.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Seller Tax Contest</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.5(d)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Semi-Fundamental Representations</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the representations and warranties contained in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.11</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (Compliance with Laws&#59; FDA) and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.20</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (Intellectual Property).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Series A-1 Preferred Stock</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the preferred stock of the Company, par value $0.0001 per share, designated as Series A-1 Preferred Stock in the Company Charter.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Series A-2 Preferred Stock</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the preferred stock of the Company, par value $0.0001 per share, designated as Series A-2 Preferred Stock in the Company Charter.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Shareholder TeneoOne Payment</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.11</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Shares</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, collectively, the Common Shares and the Preferred Shares.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Stockholder Notice</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 6.6</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Stockholder Representative</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 12.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Stockholder Representative Expense Fund</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Stockholder Representative Expenses</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Straddle Period</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any Tax period beginning on or prior to the Closing Date and ending after the Closing Date.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Straddle Period Tax Return</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.5(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Subsidiary</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, with respect to a Person, a corporation or other entity of which more than fifty percent (50%) of the voting power of the equity securities or Equity Interests is owned, directly or indirectly, by such Person&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> that with respect to the Company, each of the Teneo Subsidiaries shall be considered a &#8220;Subsidiary&#8221; but no Excluded Entity shall be considered a &#8220;Subsidiary&#8221; for purposes of this Agreement (unless otherwise specified).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Surviving Corporation</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 2.1(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Target Closing Date Net Working Capital</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means negative two million five hundred thousand U.S. Dollars ($2,500,000).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Tax Authority</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any Governmental Authority having or purporting to exercise jurisdiction with respect to any Tax.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Tax Contest</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.5(d)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">20</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Tax Returns</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any return, declaration, report, statement, information statement or other document filed or required to be filed with any Tax Authority with respect to Taxes, including any claims for refunds of Taxes and any amendments or supplements of any of the foregoing.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Taxes</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means all federal, state, local, foreign or other taxes, including all income, gross receipts, license, payroll, employment, excise, severance, stamp, occupation, premium, windfall profits, environmental, escheat, customs duties, capital stock, ad valorem, value added, inventory, franchise, profits, withholding, social security (or similar), unemployment, disability, real property, personal property, sales, use, transfer, registration, alternative or add-on minimum, or estimated taxes, and including any interest, penalty or addition thereto, whether disputed or not. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoEight</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means TeneoEight, Inc., a Delaware corporation. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoFive</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means TeneoFive, Inc., a Delaware corporation. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoFour</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means TeneoFour, Inc., a Delaware corporation. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoFour Business</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the business, operations, assets and liabilities of TeneoFour as of the date hereof concerning the development and commercialization of TNB738.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoNine</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means TeneoNine, Inc., a Delaware corporation. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoOne</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means TeneoOne, Inc., a Delaware corporation. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoOne Business</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the business, operations, assets and liabilities of TeneoOne as of the date hereof concerning the development and commercialization of TNB383B.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoOne Proceeds</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means all payments received by the Company at the closing of the TeneoOne Sale and all payments received by the Company through the release of amounts escrowed at the closing of the TeneoOne Sale, in each case as a result of the Company&#8217;s equity ownership of TeneoOne in connection with the TeneoOne Sale. For the avoidance of doubt, the TeneoOne Proceeds shall not include any milestone payments received pursuant to the TeneoOne Sale.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoOne Sale</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the sale of the stock of TeneoOne to AbbVie pursuant to that Warrant to Purchase Common Stock by and between TeneoOne and AbbVie, dated February 8, 2019. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#91;***&#93;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoSeven</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means TeneoSeven, Inc., a Delaware corporation. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoSix</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means TeneoSix, Inc., a Delaware corporation. </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">21</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Teneo Subsidiaries</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means all Subsidiaries of the Company other than the Excluded Entities.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoTen</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means TeneoTen, Inc., a Delaware corporation. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoTen Business</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the business, operations, assets and liabilities of TeneoTen as of the date hereof concerning the development and commercialization of bi-specific antibodies binding to the surface antigen of Hepatitis B (HBsAg) and CD3.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoThree</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means TeneoThree, Inc., a Delaware corporation. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoTwo</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means TeneoTwo, Inc., a Delaware corporation. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TeneoTwo Business</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the business, operations, assets and liabilities of TeneoTwo as of the date hereof concerning the development and commercialization of TNB486.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TCE Platform</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the T-cell engager antibody engineering capability platform that generates bi-specific antibodies that contain &#91;***&#93;.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Third Party Claim</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.5(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Third Phase I Clinical Candidate</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(a)(v)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TNB-585</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the PSMA x CD3 T-cell engaging bispecific antibody with the heavy and light chain amino acid sequences as set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Annex A</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TNB-585 Product</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(b)(x)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Transaction Documents</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means the Escrow Agreement, the Second Amended and Restated License Agreements, and all other agreements, instruments and certificates contemplated herein or therein to which any Party is a party. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Transaction Expenses</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means all fees, costs, expenses and other amounts incurred by or on behalf of the Company in connection with this Agreement, the Merger, the Restructuring and the other transactions contemplated hereby, including (a) those of investment bankers or other financial advisors, financial sponsors, legal counsel, accounting, consulting and other advisors, (b)&#160;those of third parties incurred by the Company in connection with the negotiation and effectuation of the terms and conditions of this Agreement and the transactions contemplated hereby, (c) the Company D&#38;O Policy,&#160;and (d)&#160;transaction bonuses, retention payments, or change of control payments payable to a service provider of the Company or its Subsidiaries solely as a result of the consummation of the Closing, including amounts payable pursuant to any phantom unit award agreement with the Company or any Subsidiary, and the employer portion of any employment Taxes that are incurred by the Company or its Subsidiaries in connection with the payment of any amounts described in this subclause (d)&#160;or in connection with the payment of any amounts under this Agreement with respect to Company Options, including, for the avoidance of doubt, Milestone Payments, but, in all cases, excluding (i) any such payment that is payable or any amount that is accrued or credited and that would become payable (and all such </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">22</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Taxes due and payable by the Company with respect thereto) as a result of&#58; (x) the termination of the employment or service relationship of any officer, director, employee or consultant of the Company that occurs after the Closing, or (y) any arrangement put in place by or at the written request of Buyer, or (ii)&#160;any such payment to the extent accrued for in the Net Working Capital as of the Closing.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Transfer Taxes</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any transfer, sales, use, stamp, documentary, registration, conveyance, recording, or other similar Tax (including all applicable real estate transfer Taxes) payable as a result of the consummation of the transactions contemplated hereby.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">UniRat&#8482; Platform</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means &#91;***&#93;.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Written Consent</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in the Recitals. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Year-End Financial Statements</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; has the meaning specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 1.2&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Construction</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Unless the context of this Agreement otherwise requires, (a) words of any gender include each other gender&#59; (b) words using the singular or plural number also include the plural or singular number, respectively&#59; (c) the terms &#8220;hereof,&#8221; &#8220;herein,&#8221; &#8220;hereby,&#8221; &#8220;hereto&#8221; and derivative or similar words refer to this entire Agreement&#59; (d) the terms &#8220;Article,&#8221; &#8220;Section,&#8221; &#8220;Schedule,&#8221; &#8220;Exhibit&#8221; or &#8220;Annex&#8221; refer to the specified Article or Section of, or Schedule, Exhibit or Annex to, this Agreement&#59; (e) the word &#8220;including&#8221; shall mean &#8220;including, without limitation,&#8221; and (f) unless the context of this Agreement otherwise requires, the word &#8220;or&#8221; shall be disjunctive but not exclusive.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;Unless the context of this Agreement otherwise requires, references to agreements and other documents shall be deemed to include all subsequent amendments and other modifications thereto.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;Unless the context of this Agreement otherwise requires, references to statutes shall include all rules and regulations promulgated thereunder.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;The language used in this Agreement shall be deemed to be the language chosen jointly by the parties to express their mutual intent and no rule of strict construction shall be applied against any party.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;Whenever this Agreement refers to a number of days, such number shall refer to calendar days unless Business Days are specified.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;The phrase &#8220;to the extent&#8221; shall mean the degree to which a subject or other thing extends, and such phrase shall not mean simply &#8220;if.&#8221;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(f)&#160;&#160;&#160;&#160;All amounts payable pursuant to this Agreement shall be paid in U.S. dollars, and all references to &#8220;$&#8221; or &#8220;dollars&#8221; shall mean the lawful currency of the United States of America.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 1.3&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Knowledge</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. As used herein, the phrase &#8220;to the knowledge&#8221; of any party shall mean the knowledge of, in the case of the Company, the individuals listed on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 1.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">23</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">including in each case the knowledge that such individuals would have after reasonable inquiry of such person&#8217;s direct reports, and in the case of all other parties, such party&#8217;s executive officers.</font></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">ARTICLE II.<br>THE MERGER&#59; CLOSING</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 2.1&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">The Merger</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;Upon the terms and subject to the conditions set forth in this Agreement, and in accordance with the applicable provisions of the DGCL, Buyer, Merger Sub and the Company (Merger Sub and the Company sometimes being referred to herein as the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Constituent Corporations</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) shall cause Merger Sub to be merged with and into the Company effective as of the Effective Time, with the Company being the surviving corporation (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Merger</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). The Merger shall be consummated at the Effective Time in accordance with this Agreement and evidenced by a certificate of merger relating to the Merger in substantially the form of </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Exhibit&#160;B</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Certificate of Merger</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;Upon consummation of the Merger, the separate corporate existence of Merger Sub shall cease and the Company, as the surviving corporation of the Merger (hereinafter referred to for the periods at and after the Effective Time as the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Surviving Corporation</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), shall continue its corporate existence under the DGCL as a wholly owned Subsidiary of Buyer.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 2.2&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Effects of the Merger</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. At and after the Effective Time, the effect of the Merger shall be as provided in this Agreement and the applicable provisions of the DGCL. Without limiting the foregoing, the Surviving Corporation shall thereupon and thereafter possess all of the rights, property, privileges, powers and franchises, of a public as well as a private nature, of the Constituent Corporations, and shall become subject to all the restrictions, disabilities and duties of each of the Constituent Corporations.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 2.3&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing&#59; Effective Time</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Subject to the terms and conditions of this Agreement, the closing of the Merger (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) shall be conducted remotely via the electronic exchange of documents and signatures as soon as practicable on or after the execution and delivery of this Agreement, but in any event no later than the date which is three (3) Business Days after the date on which all conditions set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article IX</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall have been satisfied or waived (other than those conditions that by their nature are to be satisfied at the Closing, but subject to the satisfaction or waiver of such conditions) or such other time and place as Buyer and the Company may mutually agree in writing. The date on which the Closing actually occurs is referred to in this Agreement as the &#8220;Closing Date.&#8221; Subject to the satisfaction or waiver of all of the conditions set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article IX</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that this Agreement has not theretofore been terminated pursuant to its terms, Buyer, Merger Sub and the Company shall cause the Certificate of Merger to be executed, acknowledged and filed with the Secretary of State of the State of Delaware as provided in Section 251 of the DGCL. The Merger shall become effective at the time when the Certificate of Merger has been duly filed with the Secretary of State of the State of Delaware or at such later time as may be agreed by Buyer and the Company in writing and specified in the Certificate of Merger (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Effective Time</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;).</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">24</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 2.4&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Certificate of Incorporation and Bylaws of the Surviving Corporation</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;At the Effective Time, the Company Charter shall be amended as of the Effective Time to read in its entirety in the form of the certificate of incorporation attached hereto as </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Exhibit&#160;C</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, and, as so amended, shall become the certificate of incorporation of the Surviving Corporation until thereafter amended in accordance with the applicable provisions of the DGCL and such certificate of incorporation. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;The parties hereto shall take all actions necessary so that the Company Bylaws shall, from and after the Effective Time, be amended in their entirety in the form of the bylaws of Merger Sub as in effect immediately prior to the Effective Time (except that all references to the name of Merger Sub shall be changed to refer to the name of the Company), until thereafter amended in accordance with the applicable provisions of the DGCL, the certificate of incorporation of the Surviving Corporation and such bylaws.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 2.5&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Directors and Officers of the Surviving Corporation</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;The directors of Merger Sub immediately prior to the Effective Time shall be the directors of the Surviving Corporation immediately after the Effective Time, each to hold office in accordance with the certificate of incorporation and bylaws of the Surviving Corporation until their respective successors are duly elected or appointed and qualified or until their earlier death, resignation or removal in accordance with the certificate of incorporation and bylaws of the Surviving Corporation. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;The officers of Merger Sub immediately prior to the Effective Time shall be the officers of the Surviving Corporation immediately after the Effective Time, each to hold office in accordance with the certificate of incorporation and bylaws of the Surviving Corporation until their respective successors are duly appointed or until their earlier death, resignation or removal in accordance with the certificate of incorporation and bylaws of the Surviving Corporation. </font></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">ARTICLE III.<br>EFFECTS OF THE MERGER ON THE CAPITAL STOCK AND EQUITY AWARDS</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.1&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Conversion of Company Shares&#59; Treatment of Company Options</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;At the Effective Time, by virtue of the Merger and without any further action on the part of any stockholder of the Company, Buyer or Merger Sub, each share of Company Capital Stock held by Buyer, Merger Sub or the Company in treasury or otherwise, shall be canceled and retired and shall cease to exist, and no consideration shall be delivered or receivable in exchange therefor (such shares, &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Cancelled Shares</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). At the Effective Time, by virtue of the Merger and without any action on the part of any Pre-Closing Holder (other than compliance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.2(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> by the applicable holder), (i) each share (a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Common Share</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) of Common Stock that is issued and outstanding immediately prior to the Effective Time (including restricted Common Shares, but other than (A) Cancelled Shares and (B) shares (each, a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Dissenting Share</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) of Company Capital Stock held by Persons who object to the Merger and comply with the provisions of the DGCL and CGCL concerning the rights of holders of </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">25</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Company Capital Stock to dissent from the Merger and require appraisal of their shares of Common Stock (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Dissenting Stockholders</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), which Cancelled Shares and Dissenting Shares shall not constitute &#8220;Common Shares&#8221; hereunder) and (ii) each share (a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Preferred Share</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) of Preferred Stock that is issued and outstanding immediately prior to the Effective Time (other than (A) Cancelled Shares and (B) Dissenting Shares, which Cancelled Shares and Dissenting Shares shall not constitute &#8220;Preferred Shares&#8221; hereunder), in each case, shall thereupon be canceled and converted into and become the right to receive the applicable portion of the Final Merger Consideration as set forth on the Payment Spreadsheet (as defined below).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;At the Effective Time, by virtue of the Merger and without any action on the part of Buyer or Merger Sub, each share of common stock, par value $0.0001 per share, of Merger Sub shall be converted into one share of common stock, par value $0.0001 per share, of the Surviving Corporation.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;Subject to the adjustments set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Merger Consideration</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; shall consist of nine hundred million U.S. Dollars ($900,000,000) in cash, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">plus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (i) the Estimated Net Working Capital Adjustment Amount, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">less</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (ii)&#160;the Estimated Closing Date Funded Debt, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">plus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (iii) the Estimated Closing Date Cash, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">plus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (iv) the Aggregate Option Exercise Price, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">less</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (v)&#160;the amount of the Stockholder Representative Expense Fund, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">less</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (vi) any Estimated Closing Date Transaction Expenses that remain unpaid as of the Closing. The &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Final Merger Consideration</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; shall consist of the Closing Merger Consideration </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">plus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (A) any Milestone Payment Amount paid pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">less</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (B) any Transaction Expenses paid as a result of any Milestone Payments pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10,</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">plus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (C) amounts paid to the Pre-Closing Holders pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.11</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, if any.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;Not less than five (5) Business Days prior to the Closing Date, the Company shall deliver to the Exchange Agent and Buyer a spreadsheet (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Payment Spreadsheet</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), certified as true, correct and complete in all respects by an officer of the Company, that sets forth&#58; (i)&#160;the portion of the Closing Merger Consideration that each Pre-Closing Holder is entitled to receive&#59; (ii) the portion of the Closing Merger Consideration that each Pre-Closing Holder will be deemed to have deposited with the Escrow Agent as part of the Escrow Funds&#59; (iii)&#160;the amounts and payees of any Funded Debt, if any, outstanding as of the Effective Time&#59; (iv) the amounts of any Transaction Expenses that remain unpaid as of immediately prior to the Closing and the payees to whom such amounts are owed&#59; (v)&#160;wire instructions with respect to all amounts designated in such spreadsheet&#59; (vi) each Pre-Closing Holder&#8217;s Pro-Rata Percentage&#59; (vii)&#160;the amount of the Stockholder Representative Expense Fund&#59; (viii) the amount payable to each PreClosing Holder for each Milestone Payment that becomes payable, if any, pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#59; and (ix) the amounts of any Transaction Expenses that become payable as a result of any Milestone Payment that is paid, if any, pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and the payees to whom such amounts are owed. The Company shall provide promptly to Buyer all information and reasonable access to the Company&#8217;s personnel, books and records as Buyer shall reasonably request in connection with its review of the Payment Spreadsheet, including all work papers of the accountants who audited, compiled or reviewed such statement. The Company shall revise and deliver an updated Payment Spreadsheet to the Exchange Agent and Buyer, certified as true, correct and complete in all respects by an officer of the Company, which shall reflect changes </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">26</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">thereto as have been reasonably requested by Buyer or the Exchange Agent. </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Annex B</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth a pro forma Payment Spreadsheet as if the Closing had occurred on August 31, 2021 (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pro Forma Payment Spreadsheet</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;From and after the Effective Time, (i) holders of Certificates shall cease to have any rights as stockholders of the Company and (ii) the consideration paid pursuant to this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article&#160;III</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> upon the surrender of Certificates in accordance with the terms hereof shall be deemed to have been paid in full satisfaction of all rights pertaining to the Shares, subject to the continuing rights of the Pre-Closing Holders under this Agreement and the Escrow Agreement. At the Effective Time, the transfer books of the Company shall be closed and no transfer of Shares shall be made thereafter.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(f)&#160;&#160;&#160;&#160;Immediately prior to the Effective Time, by virtue of the Merger and without any further action on the part of the Company or any other Person, each unexpired, unexercised option to purchase Common Shares (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Options</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) granted pursuant to the Company Equity Plan that is vested prior to, becomes vested in connection with, the Closing, will be cancelled and, in exchange therefor, each former holder of any such cancelled Company Option will be entitled to receive, in consideration of such cancelled Company Option and in full settlement therefor, a payment in cash of an amount equal to the applicable portion of the Final Merger Consideration as set forth on the Payment Spreadsheet (the aggregate consideration to be paid to holders of Company Options at Closing, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Option Consideration</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">,&#8221; and the aggregate consideration to be paid to holders of Company Options pursuant to this Agreement, including </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> hereof, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Option Consideration</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). Immediately prior to the Effective Time, by virtue of the Merger and without any further action on the part of the Company or any other Person, each Company Option granted pursuant to the Company Equity Plan that is not vested prior to, and does not becomes vested in connection with, the Closing, will be cancelled for no consideration, and each former holder of any such cancelled Company Option will have no further rights or entitlements with respect to any such cancelled Company Option.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(g)&#160;&#160;&#160;&#160;At or prior to the Effective Time, the Company shall take, and the board of directors of the Company shall adopt any resolutions required to approve, all actions which are necessary to (i) terminate, effective as of the Effective Time, the Company Equity Plan in accordance with its terms, and (ii) either (x) terminate, effective as of the Effective Time, all Company Options, in accordance with the terms of the Company Equity Plan, such that from and after the Effective Time no employee or other service provider of the Company or any participant under the Company Equity Plan shall have any option to purchase Common Shares or any other Equity Interest in the Company, or (y) effectuate the provisions of this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> as it relates to Company Options. The Company shall take all actions necessary to ensure that, from and after the Effective Time, the Surviving Corporation will be required to deliver the Option Consideration to former holders of Company Options.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.2&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Payments and Exchange of Certificates</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;At the Effective Time, Buyer shall pay or cause to be paid to Citibank, N.A., or such other agent as engaged by Buyer in its sole discretion (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Exchange Agent</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) by wire transfer of immediately available funds, an amount (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Funding Amount</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) equal to (i) the </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">27</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Closing Merger Consideration (determined before giving effect to the adjustments provided for in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">), </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">minus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (ii) the product of (A) the number of Dissenting Shares and (B) the per share portion of the Closing Merger Consideration that each Pre-Closing Holder is entitled to receive, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">minus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (iii)&#160;the Escrow Amount, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">minus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (iv) the Closing Option Consideration&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that Buyer will promptly thereafter pay to the Exchange Agent any amounts by which the Funding Amount increases due to any Dissenting Shares becoming Shares in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;After the Effective Time, each Pre-Closing Holder of an outstanding certificate or certificates for shares of Company Capital Stock (collectively, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Certificates</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), upon surrender of such Certificates and a duly completed and validly executed letter of transmittal in a form reasonably acceptable to Buyer (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Letter of Transmittal</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) to the Exchange Agent, shall be entitled to receive from the Exchange Agent in exchange therefor (subject to the provisions of </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">) such portion of the Final Merger Consideration into which such holder&#8217;s Shares shall have been converted as a result of the Merger&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that a portion of the Closing Merger Consideration equal to the Escrow Amount otherwise payable to each Pre-Closing Holder, in the amounts set forth on the Payment Spreadsheet, shall be held in escrow in accordance with the Escrow Agreement. Pending such surrender and exchange of a Pre-Closing Holder&#8217;s Certificate(s) a holder&#8217;s Certificate(s) shall be deemed for all purposes to evidence such holder&#8217;s right to receive the portion of the Final Merger Consideration into which such Shares shall have been converted as a result of the Merger.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;As soon as reasonably practicable following the Effective Time, but in no event later than one (1) Business Day after the Effective Time, Buyer shall deliver to the Surviving Corporation the Closing Option Consideration less the aggregate amount set forth on the Payment Spreadsheet that each holder of Company Options will be deemed to have deposited with the Escrow Agent as part of the Escrow Funds, and on or within ten (10) days following the Closing Date the Surviving Corporation shall pay to each former holder of Company Options through its payroll system (and subject to applicable Tax withholding) the Closing Option Consideration, if any, to be paid to such former holder of Company Options pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.1(f)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> hereof and as set forth on the Payment Spreadsheet. No interest will be paid or accrued upon any Option Consideration.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;At the Effective Time, Buyer (i) shall pay a portion of the Closing Merger Consideration equal to the Escrow Amount to Citibank, N.A., as escrow agent of the parties hereto (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Escrow Agent</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), to be held in escrow in accordance with the terms of the Escrow Agreement.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.3&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Estimated Net Working Capital Adjustment Amount&#59; Estimated Closing Date Funded Debt&#59; Estimated Closing Date Cash&#59; Estimated Closing Date Transaction Expenses</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Not less than four (4) Business Days prior to the Closing Date and in no event more than ten (10) Business Days prior to the Closing Date, the Company shall deliver to Buyer a written statement (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Working Capital Statement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) setting forth (a) its good faith estimate as of immediately prior to the Effective Time of (i) Closing Date Net Working Capital (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Estimated Closing Date Net Working Capital</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), (ii) Closing Date Funded Debt (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Estimated Closing Date </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">28</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Funded Debt</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), (iii) Closing Date Cash (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Estimated Closing Date Cash</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) and (iv)&#160;Closing Date Transaction Expenses (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Estimated Closing Date Transaction Expenses</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), and (b)&#160;the Company&#8217;s calculation of the Estimated Net Working Capital Adjustment Amount and Closing Merger Consideration. The Company shall prepare the Pre-Closing Working Capital Statement using the same accounting principles, procedures and policies, with consistent classifications, inclusions, exclusions and valuation and estimation methodologies that were employed in the preparation of the Sample Working Capital Statement (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Accounting Principles</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). The Company shall give Buyer a reasonable opportunity to review and comment on the Pre-Closing Working Capital Statement.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.4&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Adjustment Amount</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;On or before the ninetieth (90th) day following the Closing Date, Buyer may prepare and deliver to the Stockholder Representative (i) a calculation of Net Working Capital (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Date Net Working Capital</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), (ii)&#160;a calculation of the aggregate amount of all Funded Debt of the Company (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Date Funded Debt</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), (iii) a calculation of Cash of the Company (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Date Cash</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) and (iv) a calculation of Transaction Expenses of the Company (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Date Transaction Expenses</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), in each case, calculated as of immediately prior to the Effective Time (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Closing Working Capital Statement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). In the event that the Buyer does not provide the foregoing within such ninety (90)-day period, the Buyer shall be deemed to have agreed to the Closing Working Capital Statement and the calculations of Closing Date Net Working Capital, Closing Date Funded Debt, Closing Date Cash and Closing Date Transaction Expenses delivered by the Company, which shall be final, binding and conclusive for all purposes hereunder.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;If the Stockholder Representative shall disagree with such calculations of Closing Date Net Working Capital, Closing Date Cash, Closing Date Funded Debt, or Closing Date Transaction Expenses, it shall notify Buyer of such disagreement in writing, setting forth in reasonable detail the particulars of such disagreement, within thirty (30) days after its receipt of the Closing Working Capital Statement. In the event that the Stockholder Representative does not provide a notice of disagreement within such thirty (30)-day period, the Stockholder Representative and Buyer shall be deemed to have agreed to the Closing Working Capital Statement and the calculations of Closing Date Net Working Capital, Closing Date Funded Debt, Closing Date Cash and Closing Date Transaction Expenses delivered by Buyer, which shall be final, binding and conclusive for all purposes hereunder. In the event any notice of disagreement is timely provided, Buyer and the Stockholder Representative shall use reasonable best efforts for a period of fifteen (15) days (or such longer period as they may mutually agree) to resolve any disagreements with respect to the calculations of Closing Date Net Working Capital, Closing Date Funded Debt, Closing Date Cash or Closing Date Transaction Expenses. If, at the end of such period, they are unable to resolve such disagreements, then any such remaining disagreements shall be resolved by KPMG LLP or such other independent accounting or financial consulting firm of recognized national standing as may be mutually selected by Buyer and the Stockholder Representative (such firm, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Independent Auditor</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). Each of Buyer and the Stockholder Representative shall promptly provide their respective assertions regarding Closing Date Net Working Capital, Closing Date Funded Debt, Closing Date Cash and Closing </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">29</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Date Transaction Expenses in writing to the Independent Auditor and to each other. The Independent Auditor shall be instructed to render its determination with respect to such disagreements as soon as reasonably possible (which the parties hereto agree should not be later than thirty (30) days following the day on which the disagreement is referred to the Independent Auditor). The Independent Auditor shall base its determination solely on (i) the written submissions of the parties and shall not conduct an independent investigation and (ii) the extent (if any) to which Closing Date Net Working Capital, Closing Date Funded Debt, Closing Date Cash or Closing Date Transaction Expenses require adjustment (only with respect to the remaining disagreements submitted to the Independent Auditor) in order to be determined in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (including the definitions of the defined terms used in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">). In resolving any disputed item, the Independent Auditor may not assign a value to any item greater than the greatest value for such item claimed by either party or less than the smallest value for such item claimed by either party. The determination of the Independent Auditor shall be final, conclusive and binding on the parties. The date on which Closing Date Net Working Capital, Closing Date Funded Debt, Closing Date Cash and Closing Date Transaction Expenses are finally determined in accordance with this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> is hereinafter referred to as the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Determination Date</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.&#8221; All fees and expenses of the Independent Auditor relating to the work, if any, to be performed by the Independent Auditor hereunder shall be borne pro rata as between Buyer, on the one hand, and the Stockholder Representative as a Stockholder Representative Expense, on the other hand, in proportion to the allocation of the dollar value of the amounts in dispute as between Buyer and the Stockholder Representative (set forth in the written submissions to the Independent Auditor) made by the Independent Auditor such that the party prevailing on the greater dollar value of such disputes pays the lesser proportion of the fees and expenses. For example, if the Stockholder Representative challenges items underlying the calculations of Closing Date Net Working Capital, Closing Date Funded Debt, Closing Date Cash and Closing Date Transaction Expenses in the net amount of one million U.S. Dollars ($1,000,000), and the Independent Auditor determines that Buyer has a valid claim for four hundred thousand U.S. Dollars ($400,000) of the one million U.S. Dollars ($1,000,000), Buyer shall bear sixty percent (60%) of the fees and expenses of the Independent Auditor and the Stockholder Representative shall bear the remaining forty percent (40%) of the fees and expenses of the Independent Auditor as a Stockholder Representative Expense.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;The &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Adjustment Amount</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">,&#8221; which may be positive or negative, shall mean (i)&#160;Closing Date Net Working Capital (as finally determined in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">), </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">minus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> Estimated Closing Date Net Working Capital, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">plus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (ii) Estimated Closing Date Funded Debt, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">minus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> Closing Date Funded Debt (as finally determined in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">), </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">plus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (iii) Closing Date Cash (as finally determined in accordance with Section 3.4(b)), </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">minus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> Estimated Closing Date Cash </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">plus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (iv) Estimated Closing Date Transaction Expenses, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">minus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> Closing Date Transaction Expenses (as finally determined in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">). The Adjustment Amount shall be paid in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;If (i) the Adjustment Amount is a positive number, then, within five (5) Business Days of the Determination Date, Buyer shall pay to the Exchange Agent for distribution to each Pre-Closing Holder (</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that amounts payable in respect of Company Options shall be paid to the Surviving Corporation for payment through its payroll system) an amount in cash equal to </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">30</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(A) such holder&#8217;s Pro-Rata Percentage, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">multiplied</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">by</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (B) the Adjustment Amount, less any applicable withholding, and (ii) the Adjustment Amount is a negative number (the absolute value of such amount, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Deficit Amount</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), then within five (5) Business Days of the Determination Date, the Escrow Agent shall pay, from the Adjustment Escrow Funds, to Buyer an amount equal to the Deficit Amount&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that if the Adjustment Amount as finally determined pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(c)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> is less than the Adjustment Escrow Funds, each of Buyer and the Stockholder Representative shall execute joint written instructions to the Escrow Agent instructing the Escrow Agent to disburse any such excess amount to the Exchange Agent to be paid to the Pre-Closing Holders as Final Merger Consideration in accordance with each Pre-Closing Holder&#8217;s Pro-Rata Percentage. Upon determination of the Adjustment Amount pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(c)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, each of Buyer and the Stockholder Representative shall execute joint written instructions to the Escrow Agent instructing the Escrow Agent to disburse the Adjustment Escrow Funds in accordance with this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(d)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;Any payments made to any party pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall constitute an adjustment of the Closing Merger Consideration for Tax purposes and shall be treated as such by Buyer and the Company on their Tax Returns to the greatest extent permitted by Law.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.5&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Stockholder Representative Expense Fund</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. On the Closing Date, Buyer shall pay an amount equal to three million U.S. dollars ($3,000,000) (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Stockholder Representative Expense Fund</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) by wire transfer of immediately available funds to an account designated by the Stockholder Representative, to be used&#58; (i) for the purpose of paying the fees, losses, claims, damages, liabilities, costs, judgments, fines or amounts paid in settlement and expenses (including fees, disbursements and costs of counsel and other skilled professionals and in connection with seeking recovery from insurers) incurred, or that may in the future be incurred, by the Stockholder Representative on behalf of the Company and the PreClosing Holders in connection with the execution of this Agreement, the Escrow Agreement, the Stockholder Representative Engagement Agreement or the consummation of the transactions contemplated hereby or otherwise in its capacity as the Stockholder Representative (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Stockholder Representative Expenses</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), or (ii) as otherwise determined by the Advisory Group. The Stockholder Representative is not providing any investment supervision, recommendations or advice and shall have no responsibility or liability for any loss of principal of the Stockholder Representative Expense Fund other than as a result of its gross negligence or willful misconduct.  The Stockholder Representative is not acting as a withholding agent or in any similar capacity in connection with the Stockholder Representative Expense Fund and has no tax reporting or income distribution obligations.  The Pre-Closing Holders will not receive any interest on the Stockholder Representative Expense Fund and assign to the Stockholder Representative any such interest.  Subject to Advisory Group approval, the Stockholder Representative may contribute funds to the Stockholder Representative Expense Fund from any consideration otherwise distributable to the Pre-Closing Holders. For U.S. federal income and other applicable Tax purposes, the Stockholder Representative Expense Fund shall be treated as having been received by the Pre-Closing Holders and voluntarily set aside at the time of the Closing.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.6&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Exchange Agent</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">31</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;With respect to each payment to be paid by Buyer to the Pre-Closing Holders hereunder, promptly following the date that is six (6) months following the date that such payment is made by Buyer to the Exchange Agent, Buyer shall instruct the Exchange Agent to deliver to Buyer all cash, Certificates and other documents in its possession relating to such payments, and the Exchange Agent&#8217;s duties shall terminate with respect thereto. Thereafter, each Pre-Closing Holder of a Certificate (other than Certificates representing Dissenting Shares) may surrender such Certificate to Buyer and (subject to applicable abandoned property, escheat and similar Laws) receive in consideration therefor, and Buyer shall promptly pay, the portion of the Final Merger Consideration deliverable in respect thereof as determined in accordance with this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article&#160;III</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> without any interest thereon.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;The Company and the Stockholder Representative acknowledge and agree that (i)&#160;upon payment by Buyer to the Exchange Agent of any amounts required to be paid hereunder to the Exchange Agent for the benefit of the Pre-Closing Holders, Buyer shall have fully satisfied and discharged its obligations to make any such payments hereunder and Buyer, the Surviving Corporation and their respective Affiliates shall have no further liability with respect to such payments, regardless of the manner or timeliness of any subsequent distributions to the Pre-Closing Holders, and (ii) the Company prior to Closing and the Stockholder Representative after Closing shall have full responsibility for allocating any payments required to be paid by Buyer hereunder amongst the Pre-Closing Holders and Buyer and its Affiliates will be indemnified hereunder for any Losses related to any inaccuracy in such allocation.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.7&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Lost Certificate</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. In the event any Certificate has been lost, stolen or destroyed, upon the making of an affidavit of that fact by the Person claiming such Certificate to be lost, stolen or destroyed, the Exchange Agent shall issue in exchange for such lost, stolen or destroyed Certificate the Final Merger Consideration deliverable in respect thereof as determined in accordance with this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article III</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that Buyer may, in its sole discretion, or as required by the Exchange Agent, and as a condition precedent to the issuance thereof, require the Person who is the owner of such lost, stolen or destroyed certificates to provide an indemnification agreement in a form and substance acceptable to Buyer, against any claim that may be made against Buyer or the Exchange Agent with respect to the certificates alleged to have been lost, stolen or destroyed.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.8&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Dissenting Shares</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Notwithstanding the foregoing provisions of this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article III</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, the Dissenting Shares shall not be converted into a right to receive any portion of the Final Merger Consideration and the holders thereof shall be entitled to such rights as are granted by Section 262 of the DGCL. Each holder of Dissenting Shares who becomes entitled to payment for such shares pursuant to Section 262 of the DGCL or the CGCL, as applicable, shall receive payment therefor from the Surviving Corporation in accordance with the DGCL or CGCL, as applicable&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that (i)&#160;if any such holder of Dissenting Shares shall have failed to establish such holder&#8217;s entitlement to appraisal or dissenters&#8217; rights as provided in Section 262 of the DGCL or the CGCL, or (ii) if any such holder of Dissenting Shares shall have effectively withdrawn such holder&#8217;s demand for appraisal of such shares or lost such holder&#8217;s right to appraisal and payment for such holder&#8217;s shares under Section 262 of the DGCL or the CGCL, such holder shall forfeit the right to appraisal of such shares and each such share shall not </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">32</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">constitute a Dissenting Share and shall be treated as if it had been a Common Share or Preferred Share, as applicable, immediately prior to the Effective Time and converted, as of the Effective Time, into a right to receive from the Surviving Corporation the portion of the Final Merger Consideration deliverable in respect thereof as determined in accordance with this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article III</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, without any interest thereon (and such holder shall be treated as a Pre-Closing Holder). The Company will give Buyer prompt notice of all notices received by the Company pursuant to Section 262 of the DGCL or the CGCL and the opportunity to participate in all negotiations and proceedings with respect to such demands. Without the prior written consent of Buyer, the Company shall not voluntarily make any payment with respect to, or settle or offer to settle, any such demand for payment. From and after the Effective Time, no stockholder who has properly exercised and perfected appraisal or dissenters&#8217; rights pursuant to Section 262 of the DGCL or the CGCL shall be entitled to vote his or her Shares for any purpose or receive payment of dividends or other distributions with respect to his or her Shares (except dividends and distributions payable to stockholders of record at a date which is prior to the Effective Time). Any communication to be made by the Company to any stockholder with respect to Dissenting Shares shall be submitted to Buyer in advance and shall not be presented to any stockholder prior to the Company receiving Buyer&#8217;s prior written consent.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.9&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Withholding</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Buyer, the Company, the Surviving Corporation, the Stockholder Representative, the Exchange Agent and the Escrow Agent shall be entitled to deduct and withhold from the consideration otherwise payable or deliverable in connection with the transactions contemplated by this Agreement, to any Person such amounts that Buyer, the Company, the Stockholder Representative, the Exchange Agent and the Escrow Agent are required to deduct and withhold with respect to any such deliveries and payments under the Code or any provision of state, local, provincial or foreign Law. Any party otherwise proposing to withhold from a payment to be made pursuant to this Agreement shall use commercially reasonable efforts to provide at least ten (10) days&#8217; advance written notice to the party on behalf of which such withholding is to be made, and shall cooperate with any reasonable request by such party to reduce or eliminate the obligation to withhold. To the extent that amounts are withheld, and duly and timely deposited with the appropriate Governmental Authority, by Buyer, the Company, the Surviving Corporation, the Stockholder Representative, the Exchange Agent or the Escrow Agent, such withheld amounts shall be treated for all purposes of this Agreement as having been paid to the person in respect of which such deduction and withholding was made.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.10&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Milestone Payments</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;Additional payments in cash (each, a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Milestone Payment</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) shall be made by Buyer to the Exchange Agent for distribution as set forth on the Payment Spreadsheet pursuant to this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> upon the achievement of the milestones set forth below&#58; &#91;***&#93;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Until the earlier of (i) &#91;***&#93; after the Closing Date and (ii)&#160;the payment of all Milestone Payments payable under this Agreement, within thirty (30) days after the end of each calendar year, Buyer shall submit to the Shareholder Representative a written report (each, a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Milestone Report</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) certified as accurate by an officer in Buyer&#8217;s research and development function describing with respect to each Milestone above, the progress that has been made towards </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">33</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">achieving such Milestone, which Milestone Report shall be reasonably detailed to enable the Shareholder Representative to determine on a Milestone-by-Milestone basis, the progress that has been achieved&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the first Milestone Report hereunder shall be due on January 31, 2023.  At the request of Shareholder Representative, Buyer shall make available to the Shareholder Representative or its designee an individual to answer commercially reasonable questions that the Shareholder Representative may have based on a review of the Milestone Report.  All reports, materials and information, including each Milestone Report, provided to the Shareholder Representative under this Section&#160;3.10 shall be subject to a reasonable and customary confidentiality agreement between Buyer and the Shareholder Representative.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">For the avoidance of doubt, each of the Milestone Payments shall be payable only once upon the first achievement of the corresponding Milestone, no amounts shall be due for subsequent or repeated achievement of any such Milestone and no more than one Milestone Payment under clauses (iii)-(vi) and (vii)-(x) of this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, respectively, shall be paid for each Preclinical Company Milestone Candidate. </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">I</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">n accordance with the foregoing, the maximum total Milestone Payments payable by Buyer shall not exceed one billion six hundred million U.S. Dollars ($1,600,000,000). Notwithstanding anything herein to the contrary, Buyer may only reduce the Milestone Payments pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and by the amount of any Transaction Expenses not previously deducted from amounts otherwise paid hereunder or any Transaction Expenses arising as a result of such Milestone Payment, as applicable. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Certain Definitions</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(i)&#160;&#160;&#160;&#160;&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Clinical Trial</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, a research study in which a drug is administered or dispensed to, or used involving, human subjects, as described in 21 C.F.R. 312.3(b).</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(ii)&#160;&#160;&#160;&#160;&#91;***&#93;.</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(iii)&#160;&#160;&#160;&#160;&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">IND</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means (a) an Investigational New Drug Application as defined in the FDCA and described in 21 C.F.R. Part 312 and (b) all supplements and amendments thereto. </font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(iv)&#160;&#160;&#160;&#160;&#91;***&#93;.</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(v)&#160;&#160;&#160;&#160;&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Milestone Payment Amount</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, with respect to each Milestone identified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> the amount that becomes payable in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> upon the achievement of such Milestone.</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(vi)&#160;&#160;&#160;&#160;&#91;***&#93;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(vii)&#160;&#160;&#160;&#160;&#91;***&#93;.</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(viii)&#160;&#160;&#160;&#160;&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Preclinical Company Milestone Candidate</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means a product candidate in an Eligible Program.</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(ix)&#160;&#160;&#160;&#160;&#91;***&#93;.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">34</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(x)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8220;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">TNB-585 Product</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means any product (in any dosage, form, formulation, presentation or package configuration) that contains TNB-585</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Determining Achievement of Milestones</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Within thirty (30) days after the occurrence of a Milestone, Buyer shall provide notice to the Stockholder Representative that such Milestone has occurred.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Milestone Payment Procedures</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Within forty-five (45) days following delivery by Buyer of written notice that a Milestone has been achieved, Buyer shall pay, subject to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, by wire transfer of immediately available funds, to the Exchange Agent for the benefit of and to be distributed to the Pre-Closing Holders, the applicable amount to be paid out as set forth on the Payment Spreadsheet&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the amount set forth on the Payment Spreadsheet for delivery to the former holders of Company Options shall be paid to the Surviving Corporation for distribution through the Surviving Corporation&#8217;s payroll system.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Milestone Achievement Efforts</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Following the Effective Time, until the tenth (10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:7.8pt;font-weight:400;line-height:120%;position:relative;top:-4.2pt;vertical-align:baseline">th</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">) anniversary of the Closing Date, Buyer shall use Milestone Achievement Efforts to cause each of the Milestones to be achieved as promptly as reasonably practicable following the Closing. &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Milestone Achievement Efforts</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means, with respect to the efforts and resources to be expended, or considerations to be undertaken, by Buyer with respect to any material objective, activity or decision to be undertaken with respect to the achievement of the Milestones, reasonable efforts and resources to accomplish such objective, activity or decision that would be comparable with the efforts and prioritized resources as a similarly situated company in the biotechnology industry with resources and capabilities similarly adequate for the appropriate performance and completion of the applicable activities (a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Capable Biotech Company</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) would normally use in the exercise of its reasonable business discretion to accomplish a similar objective, activity or decision&#59; it being understood and agreed that with respect to the development and commercialization of a product, such efforts and resources shall be consistent with those efforts and resources commonly used by a Capable Biotech Company under similar circumstances with respect to a compound or product owned by it, or to which it has similar rights, which compound or product is at a similar stage in its development, commercialization or product life, is in a similar therapeutic and disease area and is of similar market potential, taking into account all scientific, commercial, and other factors that a Capable Biotech Company would reasonably be expected to take into account, including issues of safety and efficacy, expected and actual cost and time to develop, expected and actual profitability (including any payments required hereunder), expected and actual competitiveness of alternative products (including generic or biosimilar products) in development or in the marketplace, the nature and extent of expected and actual market exclusivity (including patent coverage and regulatory exclusivity), the expected likelihood of regulatory approval, the expected and actual reimbursability and pricing, and the expected and actual amounts of marketing and promotional expenditures required.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(f)&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Termination of Milestone Obligations</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Notwithstanding any other provision of this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or any other provision of this Agreement, Buyer&#8217;s obligations under this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> with respect to any Milestone (including the obligation to make Milestone </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">35</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Payments) shall terminate and be of no further force and effect if such Milestone has not been achieved by the tenth (10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:7.8pt;font-weight:400;line-height:120%;position:relative;top:-4.2pt;vertical-align:baseline">th</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">) anniversary of the Closing Date.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(g)&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Sole Agreements with Respect to Milestones</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The covenants and agreements contained in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> are the only agreements or commitments with respect to the Milestones made by Buyer or its Affiliates (including the Surviving Corporation), and except as expressly set forth in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.10</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, such development after the Effective Time shall be in Buyer&#8217;s sole discretion. The Company acknowledges it has not relied on any statements or information from Buyer other than the representations and warranties of Buyer set forth in this Agreement. The Company hereby waives, disclaims and forever relinquishes any right to any claim in respect of a Milestone Payment based on any representation, warranty, covenant or agreement other than those expressly set forth in this Agreement. For the avoidance of doubt, any right of a Pre-Closing Holder to receive any portion of the Milestone Payments (i) does not represent any equity or ownership interest in the Surviving Corporation or Buyer, and (ii) does not confer upon the Pre-Closing Holders any rights common to stockholders of the Surviving Corporation or Buyer, including any voting or dividend rights.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(h)&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Non-Transferrable</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The right to receive Milestone Payments is non-transferrable other than (i) on death by will or intestacy, (ii) pursuant to a court order, (iii) by operation of Law (including a consolidation or merger), (iv) to or for the benefit of any spouse, children, parents, uncles, aunts, siblings, grandchildren of such Pre-Closing Holder, or any of their issue (collectively, &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Approved Relatives</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) or to a trust established solely for the benefit of such Pre-Closing Holder or such Pre-Closing Holder&#8217;s Approved Relatives, or (v) without consideration in connection with the dissolution, liquidation or termination of any corporation, limited liability company, partnership or other entity. </font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.11&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">&#91;***&#93;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 3.12&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Tax Treatment</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. If and to the extent a Milestone Payment &#91;***&#93; is made to the Pre-Closing Holders, such payment shall be treated as additional consideration in the Merger and as adjustments to the Final Merger Consideration and the Option Consideration for Tax purposes, and interest will be imputed on such amount if and to the extent required by Sections 483 or 1274 of the Code. Absent a determination within the meaning of Section 1313(a) of the Code, for all applicable Tax purposes, no party hereto shall take any action or filing position inconsistent with the foregoing treatment.</font></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">ARTICLE IV.<br>REPRESENTATIONS AND WARRANTIES OF THE COMPANY</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Except as set forth in the schedules to this Agreement (each, a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; and, collectively, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Disclosure Schedules</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), the Company represents and warrants to Buyer and Merger Sub as of the date of this Agreement and as of the Closing Date as though made on the Closing Date, as follows (it being understood that each representation and warranty that calls for disclosure as contained in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article IV</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> is subject to (a) the exceptions and disclosures set forth in the section or subsection of the Disclosure Schedules corresponding to the particular section or subsection in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article IV</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> in which such representation and warranty appears&#59; and (b) any </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">36</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">exceptions or disclosures disclosed in any other section or subsection of the Disclosure Schedules to the extent that it is reasonably apparent, upon reading such disclosure, that the disclosure is responsive to such other section or subsection of this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article IV</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and such representation and warranty calls for disclosure)&#58;</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.1&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Corporate Organization of the Company</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The Company has been duly incorporated and is validly existing as a corporation in good standing under the Laws of the State of Delaware and has all requisite entity power and authority to own, license, lease and operate, as applicable, its assets and properties as they have been and are now being owned, licensed, leased and operated and to carry on its respective business as it has been and is now or presently proposed to be conducted. The copies of the Company Charter and the Company Bylaws made available by the Company to Buyer or its representatives are true and complete and in full force and effect. The Company is not in violation of any of the provisions of its organizational and governing documents, including but not limited to the Company Charter and the Company Bylaws. The Company is duly licensed or qualified to do business and (where applicable) is in good standing as a foreign corporation in each jurisdiction in which the ownership of its property or the character of its activities is such as to require it to be so licensed or qualified or in good standing, as applicable, except where the failure to be so licensed or qualified or in good standing would not reasonably be expected to be material to the Company or any of its Subsidiaries. </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth the names and titles of the directors and officers of the Company.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.2&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Subsidiaries</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;Each Subsidiary of the Company is duly organized, validly existing and in good standing under the Laws of its jurisdiction of incorporation or organization and has all requisite entity power and authority to own, license, lease and operate, as applicable, its respective assets and properties as they have been and are now being owned, licensed, leased and operated and to carry on its respective business as it has been and is now or presently proposed to be conducted. Each Subsidiary of the Company is duly licensed or qualified to do business and (where applicable) is in good standing as a foreign corporation in each jurisdiction in which the ownership of its property or the character of its activities is such as to require it to be so licensed or qualified or in good standing, as applicable, except where the failure to be so licensed or qualified or in good standing would not reasonably be expected to be material to the Company or any of its Subsidiaries. </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.2(a)(i)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth the name and jurisdiction of incorporation or organization of each Subsidiary of the Company and each jurisdiction in which each such Subsidiary of the Company is qualified, registered or licensed to do business. The Company has provided to Buyer true and complete copies of the applicable organizational and governing documents of each Subsidiary of the Company, in each case as in effect. No Subsidiary of the Company is in violation of any of the provisions of its respective organizational and governing documents. </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.2(a)(ii)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth the names and titles of the directors and officers, as applicable, of each Subsidiary of the Company. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.2(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth the authorized, issued and outstanding Equity Interests of each Subsidiary of the Company and the record ownership thereof, including with respect to stock options, the granting entity, number of shares underlying the stock option, the type </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">37</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(incentive or nonqualified), vesting schedule, expiration date, exercise price and jurisdiction. Except as listed on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.2(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, neither the Company nor any Subsidiary of the Company (i)&#160;owns, directly or indirectly, any equity, economic, voting or management interest in any other Person or any share capital, debt instruments, voting securities or other interests exercisable or exchangeable for, or convertible into, any of the foregoing or (ii)&#160;is party to any partnership or joint venture agreement. No Subsidiary of the Company has any obligation or liability regarding the making of any investment (in the form of a loan, capital contribution or otherwise) in any other Person. All of the outstanding Equity Interests of each Subsidiary of the Company are duly authorized, validly issued, fully paid and nonassessable, are owned free and clear of all Liens, and are not subject to, and were not issued in breach or violation of, any provision of applicable Laws, the organizational and governing documents of such Subsidiary, any Contract to which any Subsidiary of the Company is a party or is otherwise bound or any purchase option, call option, right of first refusal, preemptive right, subscription right or similar right. With respect to any stock option, (i) each grant of an option was duly authorized no later than the date on which the grant of such option was by its terms to be effective on the date the option was granted by all necessary corporate action, (ii) each option has an exercise price equal to no less than the fair market value of the underlying shares of common stock on the applicable grant date as determined by the granting entity&#8217;s board of directors in good faith and (iii) no option provides for any feature for the deferral of compensation other than the deferral of recognition of income until the later of exercise or disposition of such option, in each case, as determined in accordance with Section 409A of the Code. </font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.3&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Due Authorization</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;The Company has all requisite corporate power and authority to enter into this Agreement and, subject to the receipt of the Merger Consent, to consummate the Merger and the other transactions contemplated hereby. The Merger Consent is sufficient for the holders of the Company Capital Stock to adopt this Agreement, and no other corporate proceedings are necessary to authorize this Agreement or to consummate the Merger and the other transactions contemplated hereby (other than the filing and recordation of the Certificate of Merger and such other documents as required in accordance with the provisions of the DGCL). The board of directors of the Company has unanimously (i) declared that the Merger and the other transactions contemplated by this Agreement are advisable, fair to and in the best interests of the Company and its stockholders, (ii) approved this Agreement in accordance with the provisions of the DGCL and the CGCL, (iii) directed that this Agreement and the Merger be submitted to the stockholders of the Company for their adoption and approval by written consent and (iv) resolved to recommend that the stockholders of the Company vote in favor of the adoption of this Agreement and the approval of the Merger (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Board Recommendation</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;This Agreement has been duly executed and delivered by the Company and, assuming that this Agreement constitutes a valid and binding obligation of the other parties hereto, this Agreement constitutes a valid and binding obligation of the Company, enforceable against the Company in accordance with its terms, except as such enforceability may be limited by bankruptcy, insolvency, moratorium or other similar applicable Law affecting or relating to </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">38</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">creditors&#8217; rights generally and general principles of equity, regardless of whether asserted in a proceeding in equity or at law (collectively, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Remedies Exception</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;Assuming (x) the making of all filings and notifications as may be required or advisable in connection with the Transactions under the HSR Act and any other applicable Law designed to prohibit, restrict or regulate actions having the purpose or effect of substantially lessening competition, monopolization or restraint of trade (collectively, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Antitrust Laws</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) and authorization, clearance, consent, approval or expiration or early termination of the applicable waiting period under the Antitrust Laws and (y) receipt of the Merger Consent, the execution and delivery of this Agreement by the Company does not constitute, and the consummation by the Company of the transactions contemplated hereby will not result in, a termination, cancellation, acceleration or breach or violation by the Company of, or a default by the Company under (with or without notice or lapse of time, or both), (i) any provision of the Company Charter and the Company Bylaws, (ii) any Contract or (iii) any applicable Law to the Company or any of its assets, except in the case of clause (ii) where such termination, cancellation, acceleration, breach or violation would not reasonably be expected to be material to the Company.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.4&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Vote Required</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The votes comprising the Merger Consent are the only votes, including of any class or series of Company Capital Stock required under the DGCL and the CGCL, to approve this Agreement and the transactions contemplated hereby, including the Merger. Prior to the execution and delivery of this Agreement, the Company has prepared and distributed Written Consents to Company Stockholders holding at least the number and class of shares sufficient to provide the Merger Consent.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.5&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">No Conflict</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The execution and delivery of this Agreement by the Company and the consummation by the Company of the transactions contemplated hereby do not and will not, as of the Closing, (a) violate any provision of, or result in the breach of, any applicable Law to which the Company or its Subsidiaries is subject or by which any property or asset of the Company or its Subsidiaries is bound, (b) conflict with the Company Charter and the Company Bylaws, (c) violate any provision of or result in a breach of, or require a consent under, any Contract listed on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.12</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, or terminate or result in the termination of any such Contract, or result in the creation of any Lien under any such Contract upon any of the properties or assets of the Company or its Subsidiaries, or constitute an event which, after notice or lapse of time or both, would result in any such violation, breach, termination or creation of a Lien or (d) result in a violation or revocation of any required license, permit or approval from any Governmental Authority, except to the extent that the occurrence of any item set forth in clause (c)&#160;would not reasonably be expected to be material to the Company, taken as a whole. </font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.6&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Governmental Consents</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. No consent, approval or authorization of, or designation, declaration or filing with, any Governmental Authority is required on the part of the Company or its Subsidiaries with respect to the Company&#8217;s execution or delivery of this Agreement or the consummation by the Company of the transactions contemplated hereby, except for (a) applicable requirements of the HSR Act or any similar, applicable foreign Law, (b) as otherwise </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">39</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">disclosed on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule&#160;4.6</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and (c) the filing of the Certificate of Merger in accordance with the DGCL.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.7&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Capitalization of the Company</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;The authorized capital stock of the Company consists of&#58;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:7.8pt;font-weight:400;line-height:120%;position:relative;top:-4.2pt;vertical-align:baseline"> </font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(i)&#160;&#160;&#160;&#160;52,000,000 of Common Stock, of which 6,757,270 shares are issued and outstanding as of the date of this Agreement. </font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(ii)&#160;&#160;&#160;&#160;35,726,483 shares of Preferred Stock, of which 9,726,483 shares have been designated as Series A-1 Preferred Stock, all of which are issued and outstanding as of the date of this Agreement, and 26,000,000 shares have been designated Series A-2 Preferred Stock, 25,982,598 of which are issued and outstanding as of the date of this Agreement.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">All of the issued and outstanding shares of Company Capital Stock (A) are duly authorized, validly issued, fully paid and non-assessable, (B) are free of any Liens created by the Company, (C) were not issued in violation of any preemptive rights or rights of first refusal created by applicable Law or any provisions of the Company Charter and the Company Bylaws or any agreement to which the Company is a party or by which it is bound and (D) have been issued in compliance with applicable federal and state securities or &#8220;blue sky&#8221; Laws. </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule&#160;4.7(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth, as of the date of this Agreement, the name of each holder of shares of Company Capital Stock and the true and correct number of shares of Common Stock and Preferred Stock held of record by each such stockholder. There are no accrued, declared or unpaid dividends with respect to any issued and outstanding shares of Company Capital Stock that will not be satisfied by the payment of the Final Merger Consideration hereunder.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;As of the date hereof, 8,661,970 shares of Common Stock are subject to outstanding Company Options. </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.7(b)(i)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth with respect to each Company Option, as of the date hereof, the name of the holder thereof, the number of vested and unvested shares of Common Stock subject thereto, the type (nonqualified or incentive), expiration date, the exercise price and jurisdiction, thereof. The Company has delivered to Buyer an accurate and complete copy of the Company Equity Plan. With respect to the Company Options, (i) each grant of an option was duly authorized no later than the date on which the grant of such option was by its terms to be effective on the date the option was granted by all necessary corporate action, (ii) each option was granted pursuant to the Company Equity Plan and has an exercise price equal to no less than the fair market value of the underlying shares of Common Stock on the applicable grant date as determined by the Company&#8217;s board of directors in good faith and (iii) no option provides for any feature for the deferral of compensation other than the deferral of recognition of income until the later of exercise or disposition of such option, in each case, as determined in accordance with Section 409A of the Code. A complete and accurate list of each holder of restricted Common Stock and the vesting schedule of such Common stock is set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.7(b)(ii)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. With respect to each share of restricted Common Stock, a timely election pursuant to Section 83(b) of the Code has been made and remitted to the IRS.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">40</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;Except (i) as set forth in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.7</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or (ii) as set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.7(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, the Company has not granted any outstanding options, warrants, rights or other securities convertible into or exchangeable or exercisable for shares of Common Stock, or any other commitments or agreements providing for the issuance of additional shares, the sale of treasury shares, or for the repurchase or redemption of shares of Common Stock, and there are no agreements of any kind which may obligate the Company to issue, purchase, register for sale, redeem or otherwise acquire any of its capital stock.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;Except as set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.7(d)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> there are (i) no rights, agreements, arrangements or commitments of any kind or character, whether written or oral, relating to the Equity Interest of the Company to which the Company is a party, or by which it is bound, obligating the Company to repurchase, redeem or otherwise acquire any issued and outstanding Equity Interest of the Company&#59; (ii) no outstanding or authorized stock appreciation, phantom stock, profit participation, or other similar rights with respect to the Company&#59; and (iii) no voting trusts, stockholder agreements, proxies or other agreements or understandings in effect to which the Company is a party with respect to the governance of the Company or the voting or transfer of any Equity Interest the Company.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;The Payment Spreadsheet will set forth the capitalization of the Company immediately prior to the Effective Time, taking into account the consummation of the Restructuring Plan and set forth the applicable portion of the Final Merger Consideration payable to each Pre-Closing Holder, as contemplated by this Agreement.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.8&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Financial Statements</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Attached as </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> are (a) the audited consolidated balance sheet and statements of operations, stockholders&#8217; equity and cash flow of the Company as of and for the twelve (12) month period ended December 31, 2019 (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Year-End Financial Statements</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) and (b) an unaudited consolidated balance sheet and statements of income, operations, stockholders&#8217; equity and cash flow of the Company as of and for the twelve month period ended December 31, 2020 and the six (6) month period ended June 30, 2021 (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Interim Financial Statements</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; and, together with the Year-End Financial Statements, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Financial Statements</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">,&#8221; and such date, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Balance Sheet Date</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). The Financial Statements present fairly, in all material respects, the financial position and results of operations of the Company as of the dates and for the periods indicated in such Financial Statements in conformity with the Accounting Standards on a consistent basis through the periods indicated and with each other (except in the case of the Interim Financial Statements for the absence of footnotes and other presentation items and for normal year-end adjustments). The Company maintains a standard system of accounting established and administered in accordance with GAAP.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.9&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Undisclosed Liabilities</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. There is no liability, debt or obligation of the Company of a type required to be reflected or reserved for on a balance sheet prepared in accordance with the Accounting Standards, except for liabilities and obligations (a) reflected or reserved for on the Financial Statements or disclosed in the notes thereto, (b) that have arisen since the Company Balance Sheet Date in the ordinary course of the operation of business of the Company, not exceeding one hundred thousand U.S. Dollars ($100,000), individually or in the aggregate, (c) </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">41</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">incurred in connection with the transactions contemplated by this Agreement or (d) disclosed on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.9</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.10&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Litigation and Proceedings</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. There are no pending or, to the knowledge of the Company threatened, lawsuits, actions, suits, subpoenas, investigations or civil investigative demands, claims or other proceedings at law or in equity (including any allegations or investigations of violations of any Health Care Law), in each case, before or by any Governmental Authority against the Company or any of its Subsidiaries or any officer, director, employee, manager or agent, in each case, acting for or on behalf of the Company or any of its Subsidiaries.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.11&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Compliance with Laws&#59; Governmental Authorities</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;The Company and its Subsidiaries are and have been in compliance in all material respects with all applicable Laws, including Health Care Laws, Privacy Laws, Anti-Corruption Laws, and International Trade Laws. Neither the Company nor any of its Subsidiaries have received any written notice, correspondence, or communication from any Governmental Authority alleging or asserting a violation of any applicable Law, including Health Care Laws, Privacy Laws, Anti-Corruption Laws, and International Trade Laws. Neither the Company nor any of its Subsidiaries is a party to any corporate integrity agreement, monitoring agreement, consent decree, settlement order, deferred prosecution agreement, nonprosecution agreement or similar agreement with or imposed by any Governmental Authority. To the knowledge of the Company, there are no facts, circumstances or conditions that would reasonably be expected to form the basis for any investigation, suit, claim, action, proceeding or imposition of any penalties against or affecting the businesses of the Company or any of its Subsidiaries relating to or arising out of Health Care Laws, Privacy Laws, Anti-Corruption Laws, and International Trade Laws. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;As to each of the product candidates set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.11(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> currently under research and&#47;or development by the Company and its Subsidiaries and subject to the jurisdiction of the FDA or any equivalent Governmental Authority in any legal jurisdiction other than the U.S. (including, for clarity, TNB-585 and the product candidates included in the Eligible Programs for which an IND has been filed) (each such product, a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Regulated Product</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), such Regulated Product is being and has been researched, developed, manufactured, tested, distributed and&#47;or marketed in compliance in all material respects with all applicable requirements under Health Care Laws, including the provisions of the FDCA relating to investigational use, premarket approval, good manufacturing practices, labeling, advertising, record keeping, filing of reports and security. Neither the Company nor any of its Subsidiaries have received any notice or other communication from any Governmental Authority and no Governmental Authority has or is (i) contesting the premarket approval of, the uses of or the labeling and promotion of any Regulated Product or (ii) alleging any violation by the Company or any of its Subsidiaries of any Law applicable to a Regulated Product.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;The Company is the sole and exclusive owner of all filings and applications submitted to, and all authorizations or designations granted by, the FDA and other Governmental Authorities for each Regulated Product, including any IND, BLA (to the extent applicable) or other marketing authorization, orphan drug designation and the like, of any jurisdiction, each of </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">42</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">which is set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.11(c)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (collectively, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Regulatory Filings</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), free and clear of any Liens. The Company has complied with all requirements to notify FDA and other Governmental Authorities of any transfers of ownership of Company Regulatory Filings, including orphan drug designations. All Company Regulatory Filings, including orphan drug designations, have been transferred to the Company in accordance with applicable Health Care Laws, remain valid, and have not been varied.&#160;No IND filed by or on behalf of the Company or any of its Subsidiaries with the FDA has been terminated or suspended by the FDA, and neither the FDA nor any other applicable Governmental Authority has commenced, or, to the knowledge of the Company, threatened to initiate, any action to place a clinical hold order on, or otherwise terminate, delay or suspend, any proposed or ongoing clinical investigation conducted or proposed to be conducted by or on behalf of the Company or any of its Subsidiaries.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;The Company has provided or made available to Buyer true, complete and correct copies of (i) all Company Regulatory Filings and related correspondence with applicable Governmental Authorities and (ii) all available clinical and non-clinical data (including interim data (including safety, efficacy and other available information), study reports and any summaries thereof), in each case related to (A) any Company Regulatory Filings or (B) any clinical, non-clinical, or manufacturing activities conducted by or on behalf of the Company or any of its Subsidiaries or with respect to all of the Company&#8217;s Regulated Products and Company Products (collectively, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Product Data</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). All Product Data accurately reflects in all material respects (including from a statistical standpoint) the results from the clinical, non-clinical, and manufacturing activities conducted by the Company with respect to the use of each Regulated Product or Company Product, as applicable, that was the subject thereof and the Company has not failed to disclose any such information that would reasonably be deemed to be material information with respect to any such Regulated Product or Company Product. Neither the Company nor any of its Subsidiaries has made any untrue statement of fact or fraudulent statement to the FDA or Governmental Authority or otherwise failed to disclose a material fact required to be disclosed to the FDA or Governmental Authority.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;All non-clinical studies in animals conducted by or for the benefit of the Company or any of its Subsidiaries have been, and are being, conducted in material compliance with all applicable Laws, including the applicable requirements of &#8220;Good Laboratory Practice&#8221; as promulgated by the FDA under and in accordance with Title 21, Part 58 of the U.S. Code of Federal Regulations, and the applicable standards published by the FDA that relate thereto, or any similar requirements or standards and any similar laws of any other Governmental Authority (collectively &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Good Laboratory Practice</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(f)&#160;&#160;&#160;&#160;All clinical trials conducted by or for the benefit of the Company or any of its Subsidiaries have been, and are being, conducted in compliance with all applicable Laws (including Privacy Laws), including the applicable requirements of &#8220;Good Clinical Practice,&#8221; informed consent, and all applicable requirements relating to protection of human subjects contained in Title 21, Parts 50, 54, 56, and 312 of the U.S. Code of Federal Regulations, and the applicable guidelines and standards published by the FDA that relate to the conduct of clinical studies in humans, or any similar requirements, guidelines, or standards of any other Governmental Authority, in each case as applicable (collectively, &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Good Clinical Practice</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;).</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">43</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(g)&#160;&#160;&#160;&#160;All manufacturing operations currently conducted by or for the benefit of the Company or any of its Subsidiaries relating to the Company&#8217;s or such or any of its Subsidiaries&#8217; Regulated Products have been and are being conducted in compliance with applicable current &#8220;Good Manufacturing Practice&#8221; regulations as promulgated by the FDA, including those set forth in 21 C.F.R. Parts 210 and 211 that relate to the manufacturing, quality assurance, quality control, processing, packaging, holding or distribution of drug substances and finished drugs, or any similar requirements of any other Governmental Authority (collectively, &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Good Manufacturing Practice</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(h)&#160;&#160;&#160;&#160;None of the Company, its Subsidiaries, nor, to the knowledge of the Company, any officer, employee or agent of the Company or its Subsidiaries has been convicted of any crime or engaged in any conduct that has previously caused or would reasonably be expected to result in (i) disqualification, debarment, or suspension by the FDA under 21 U.S.C. Section 335a, or any similar law, rule or regulation of any other Governmental Authority, or (ii) exclusion from federal health care programs under 42 U.S.C. Sections 1320a-7 or 1320a-7a, or any similar law, rule or regulation of any Governmental Authority.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(i)&#160;&#160;&#160;&#160;The Company has delivered to Buyer true, correct, and complete copies of all communications in its possession between the Company and its Subsidiaries and the FDA or any other applicable Governmental Authority that pertain to the Company&#8217;s ability to lawfully research, develop, test, manufacture, market or distribute the Company&#8217;s Regulated Products, or assessing compliance of the Company&#8217;s or any of its Subsidiaries&#8217; operations with respect to the Company&#8217;s Regulated Products with the FDCA and its implementing regulations or other applicable Laws, including true, correct and complete copies of (i) all warning letters, untitled letters, notices of adverse findings, clinical hold correspondence, and similar written correspondence received by the Company or any of its Subsidiaries, (ii) all inspection reports and lists of observations, including Establishment Inspection Reports and Form FDA 483s, relating to inspections for compliance with the FDCA, and (iii) any similar reports issued by a foreign Governmental Authority.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(j)&#160;&#160;&#160;&#160;The Company, its Subsidiaries and, to the knowledge of the Company, each partner, third-party service provider or third party which pursuant to a Contract with the Company or its Subsidiaries co-develops, or otherwise has a license or other right to research develop, manufacture, supply, test, or import any Regulated Product, hold all material Governmental Authorizations from the FDA and all other Governmental Authorities that are required for the conduct of the Company&#8217;s or its Subsidiaries&#8217; businesses as currently conducted, and all such Governmental Authorizations are (i) in full force and effect, (ii) validly registered and on file with applicable Governmental Authorities, if any, and (iii) in compliance with all formal filing and maintenance requirements. The consummation of the Transactions, in and of themselves, would not cause the revocation or cancellation of any such Governmental Authorization.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.12&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Contracts&#59; No Defaults</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.12</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth a true, correct and complete list of the Contracts referred to or described in clauses (i) through (xvi), inclusive, of this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.12(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, all of which are in </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">44</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">effect as of the date of this Agreement and to which the Company or a Subsidiary is a party or by which it or any of the assets owned by the Company or its Subsidiaries is bound, other than Company Benefit Plans, Contracts for labor and employment matters set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.13(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and Contracts relating to insurance policies set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.17</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (each, a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Listed Contract</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). The Company has delivered to Buyer, or made available to Buyer, a complete and accurate copy of such Listed Contract (including all amendments or modifications thereto that exist as of the date of this Agreement)&#58;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(i)&#160;&#160;&#160;&#160;other than Contracts of the type (without giving effect to dollar thresholds) described in other clauses of this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.12(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the Company reasonably anticipates will involve aggregate annual payments or consideration furnished by or to the Company or its Subsidiaries of more than one hundred thousand U.S. Dollars ($100,000)&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(ii)&#160;&#160;&#160;&#160;pursuant to which the Company or any of its Subsidiaries has continuing obligations or interests involving the payment of royalties, earnouts, development or commercialization milestones or other amounts calculated based on the revenues, income, achievement or regulatory or development milestones or other performance measure of the Company&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(iii)&#160;&#160;&#160;&#160;pursuant to which the Company or any of its Subsidiaries has material continuing obligations to any third party with respect to the manufacture or supply of products of the Company or its Subsidiaries, including any Preclinical Company Milestone Candidate, or any component or raw materials used therein&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(iv)&#160;&#160;&#160;&#160;evidencing debt of the Company or its Subsidiaries or that otherwise relates to the borrowing or lending of money or to mortgaging, pledging or otherwise placing a Lien on any portion of the assets of the Company or its Subsidiaries&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(v)&#160;&#160;&#160;&#160;that is for the acquisition of any Person or any business division thereof or the disposition of any material assets of the Company or its Subsidiaries (other than in the ordinary course of business), in each case, involving payments in excess of one hundred thousand ($100,000), other than Contracts in which the applicable acquisition or disposition has been consummated and there are no material obligations ongoing&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(vi)&#160;&#160;&#160;&#160;that is a lease, rental or occupancy agreement, real property license, installment and conditional sale agreement or other Contract that, in each case, provides for the ownership of, leasing of, title to, use of, or any leasehold or other interest in any real or personal property&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(vii)&#160;&#160;&#160;&#160;that is a joint venture, strategic alliance, partnership, transition services agreement, collaboration or other contract or agreement involving any joint ownership or sharing of any business, venture or enterprise, or a sharing of profits or losses, or pursuant to which the Company or its Subsidiaries has any ownership or control interest in any other Person or business enterprise&#59;</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">45</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(viii)&#160;&#160;&#160;&#160;that requires capital expenditures after the date of this Agreement in an annual amount in excess of one hundred thousand U.S. Dollars ($100,000)&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(ix)&#160;&#160;&#160;&#160;that provides for severance, retention, change in control or other similar payments&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(x)&#160;&#160;&#160;&#160;that results in any Person holding a power of attorney from the Company or its Subsidiaries&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xi)&#160;&#160;&#160;&#160;that is with any Governmental Authority&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xii)&#160;&#160;&#160;&#160;that is with any Person known to the Company to be a member of the Healthcare Community&#59; </font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xiii)&#160;&#160;&#160;&#160;that is a non-competition Contract or other Contract that (A) limits or purports to limit in any respect either (1) the type of business in which the Company or its Subsidiaries (or, after giving effect to the Merger, Buyer or its Affiliates) may engage (whether by lines of business, field or otherwise), including the ability to obtain or provide products or services from or to any Person (including any exclusivity obligations on the Company or any of its Subsidiaries, but excluding confidentiality and non-disclosure agreements that do not contain any restrictions other than customary confidentiality and non-disclosure obligations) or the ability to engage in developing or commercializing any product candidates with respect to any targets, (2) the geographic locations in which the Company or any of its Subsidiaries may so engage in any business or (3) the products that the Company or its Subsidiaries (or, after giving effect to the Merger, Buyer or its Affiliates) may research, develop, manufacture or commercialize, (B) grants any &#8220;most favored nation&#8221; or similar terms or rights (including terms for pricing) by the Company or any of its Subsidiaries or (C) contains minimum purchase requirements or obligations imposed on the Company or any of its Subsidiaries&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xiv)&#160;&#160;&#160;&#160;for the sale of any of the tangible assets of the Company or its Subsidiaries other than in the ordinary course of the Company&#8217;s or its Subsidiaries&#8217; businesses or for the grant to any Person of any preferential rights to purchase any of the Company&#8217;s or any of its Subsidiaries&#8217; tangible assets&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xv)&#160;&#160;&#160;&#160;that contains a &#8220;non-solicitation&#8221; or &#8220;no-hire&#8221; provision that restricts the Company or its Subsidiaries (or, after giving effect to the Merger, Buyer or its Affiliates)&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xvi)&#160;&#160;&#160;&#160;that contains an option, grants exclusivity or grants any right of first refusal, right of first negotiation or right of first offer by the Company or any of its Subsidiaries in favor of any Person (other than pursuant to the Company Equity Plan)&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xvii)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">IP Assignments&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xviii)&#160;&#160;&#160;&#160;pursuant to which the Company or any of its Subsidiaries (A) has purchased or licenses Intellectual Property from a third party, other than (i) click-wrap, </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">46</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">shrink-wrap and off-the-shelf software licenses, and any other software licenses that are available on standard terms to the public generally with license, maintenance, support and other fees less than one hundred thousand U.S. Dollars ($100,000) per year and (ii) consulting agreements that are consistent in all material respects with the Company&#8217;s form consulting agreement made available to Buyer or (B) has licensed, assigned, sold or transferred to a third party any Intellectual Property owned by the Company or such Subsidiary&#59; and</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xix)&#160;&#160;&#160;&#160;that is a Contract governing use of Shared Intellectual Property.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;Except as set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.12</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, all of the Contracts set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule&#160;4.12</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> are (i) in full force and effect and (ii) represent the valid and binding obligations of the Company or Subsidiary of the Company party thereto, as applicable, and, to the knowledge of the Company, represent the valid and binding obligations of the other parties thereto. Except as set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.12</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, (A) neither the Company nor, to the knowledge of the Company, any other party thereto is in breach of or default under any such Contract, (B) the neither the Company nor any applicable Subsidiary has received a claim or notice of breach of or default under any such Contract, and (C) to the knowledge of the Company, no event has occurred which, individually or together with other events, would reasonably be expected to result in a breach of or a default under any such Contract (in each case, with or without notice or lapse of time or both).</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.13&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Benefit Plans</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule&#160;4.13</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth a true, correct and complete list of each Company Benefit Plan</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;The Company has made available to Buyer a true and complete copy, as applicable, of (i) each Company Benefit Plan (including any amendments thereto) and descriptions of all material terms of any such plan that is not in writing, (ii) the three (3) most recent annual reports with accompanying schedules and attachments, filed with respect to each Company Benefit Plan required to make such a filing, (iii) the most recent summary plan description for each Company Benefit Plan for which a summary plan description is required by applicable law and any other notice or description provided to employees (as well as any modifications or amendments thereto), (iv) the most recently received determination letter, if any, issued by the Internal Revenue Service and each currently pending application for a determination letter with respect to any Company Benefit Plan that is intended to qualify under Section 401(a) of the Code, (v) the three most recently prepared actuarial reports, financial statements and trustee reports, if any, relating to the Company Benefit Plan, (vi) all material records, notices and filings concerning Internal Revenue Service or U.S. Department of Labor audits or investigations with respect to any Company Benefit Plan, and (vii) all non-routine, written communications relating to any Company Benefit Plan and any proposed Company Benefit Plan with any Governmental Authority.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;Each Company Benefit Plan that is intended to be qualified under Section&#160;401(a) of the Code has received a favorable determination letter from the Internal Revenue Service or is </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">47</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">the subject of a favorable opinion letter from the Internal Revenue Service on the form of such Company Benefit Plan and, to the knowledge of the Company, there are no facts or circumstances that would be reasonably likely to adversely affect the qualified status of any such Company Benefit Plan. Each trust established in connection with any Company Benefit Plan which is intended to be exempt from federal income taxation under Section 501(a) of the Code is so exempt, and no fact or event has occurred that would reasonably be expected to adversely affect the exempt status of any such trust</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;No Company Benefit Plan is, and neither any of the Company or its Subsidiaries nor any ERISA Affiliate thereof contributes to, has at any time contributed to or has any liability or obligation, whether fixed or contingent, with respect to (i) a Multiemployer Plan, (ii) a single employer plan or other pension plan that is subject to Title IV of ERISA or Section 302 of ERISA or Section 412 of the Code, (iii) a &#8220;multiple employer plan&#8221; (within the meaning of Section 413(c) of the Code), or (iv) a multiple employer welfare arrangement (within the meaning of Section 3(40) of ERISA). </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;None of the Company or any of its Subsidiaries has any obligation to provide (whether under an Company Benefit Plan or otherwise) health, accident, disability, life or other welfare benefits to any current or former employees, directors, consultants or retirees of any the Company or any of its Subsidiaries (or any spouse, beneficiary or dependent of the foregoing) beyond the termination of employment or other service of such employee, director, consultant or retiree, other than health continuation coverage pursuant to COBRA. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(f)&#160;&#160;&#160;&#160;Each Company Benefit Plan has been maintained, operated and administered in compliance in all material respects with its terms and the applicable requirements of ERISA, the Code and any other applicable laws. The Company and each of its Subsidiaries has performed all obligations required to be performed by it under, is not in any material respect in default under or in violation of, and has no knowledge of any default or violation by any party to, any Company Benefit Plan.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(g)&#160;&#160;&#160;&#160;All payments, benefits, contributions (including all employer contributions and employee salary reduction contributions) and premiums related to each Company Benefit Plan, including all wages, salaries, commissions, bonuses, benefits and other compensation due to or on behalf of any employees or other service providers, have been timely paid or made in full or, to the extent not yet due, properly accrued on the Company Balance Sheet in accordance with the terms of the Company Benefit Plan and all applicable laws.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(h)&#160;&#160;&#160;&#160;No Action is pending or, to the knowledge of the Company, threatened against, by or on behalf of any Company Benefit Plan or the assets, fiduciaries or administrators thereof (other than claims for benefits in the ordinary course). With respect to each Company Benefit Plan, (i) no breaches of fiduciary duty or other failures to act or comply in connection with the administration or investment of the assets of such Company Benefit Plan have occurred, and (ii) no lien has been imposed under the Code, ERISA or any other applicable law. There has not been any prohibited transaction (within the meaning of Section 406 of ERISA or Section 4975 of the Code) with respect to any Company Benefit Plan. None of the Company or any of its Subsidiaries has made any filing within the past six (6) years in respect of any Company Benefit </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">48</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Plan under the Employee Plans Compliance Resolution System or the Department of Labor Delinquent Filer Program.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(i)&#160;&#160;&#160;&#160;No Company Benefit Plan, and neither the Company or its Subsidiaries nor any Company Benefit Plan fiduciary with respect to any Company Benefit Plan, in any case, is the subject of an audit or investigation by the Internal Revenue Service, the Department of Labor, the Pension Benefit Guaranty Corporation or any other Governmental Authority, nor is any such audit or investigation pending or, to the knowledge of the Company, threatened.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(j)&#160;&#160;&#160;&#160;Neither the execution and delivery of this Agreement, nor the consummation of the transactions contemplated hereby, either alone or in combination with another event (whether contingent or otherwise) will (i) entitle any current or former employee, consultant, director or other service provider of the Company or any of its Subsidiaries to any payment&#59; (ii)&#160;increase the amount of compensation or benefits due to any such employee, consultant, director or other service provider or any such group of employees, consultants, directors or other service providers&#59; or (iii) accelerate the vesting, funding or time of payment of any compensation, equity award or other benefit.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(k)&#160;&#160;&#160;&#160;The Company and its Subsidiaries and each of their respective ERISA Affiliates are in compliance in all material respects with (i) the applicable requirements of Section 4980B of the Code and any similar state law, (ii) the applicable requirements of HIPAA and the regulations (including the proposed regulations) thereunder and (iii) the applicable requirements of the Patient Protection and Affordable Care Act of 2010, as amended. No Company Benefit Plan is a voluntary employee benefit association under Section 501(a)(9) of the Code. The obligations of all Company Benefit Plans that provide health, welfare or similar insurance are fully insured by bona fide third-party insurers. No Company Benefit Plan is maintained through a human resources and benefits outsourcing entity, professional employer organization, or other similar vendor or provider.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(l)&#160;&#160;&#160;&#160;The Company and its Subsidiaries have not sponsored, maintained, contributed to, or been required to sponsor, maintain, participate in or contribute to, any employee benefit plan, program, or other arrangement providing compensation or benefits to any service provider (or any dependent thereof) which is subject to the Laws of any jurisdiction outside of the United States.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.14&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Employment and Labor Relations</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.14(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth (i) a complete and accurate list as of the date that is within five (5) business days of the date of this Agreement of all of the employees of the Company and its Subsidiaries, describing or identifying for all employees their names, employee identification numbers, employing entity, position titles, annual salaries (or base hourly wage rates), target cash incentive compensation opportunity, bonuses, other compensation, assigned work location, leave of absence status, overtime and minimum wage exemption classification, full-time, part-time, temporary or seasonal employee status, and employee or independent contractor &#47; non-employee classification, Company service date and annual equity target incentive value or share award.&#160;All data not specifically listed, but reasonably necessary for </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">49</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Buyer to provide benefits, payroll, or any other employee-related service to Company employees will be timely provided to Buyer, to the extent permitted by Law.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;The Company and its Subsidiaries is and has not at any time been bound by any collective bargaining or similar agreement with respect to its employees. There is no labor strike, work stoppage, picketing, lockout, walkout or other organized work interruption pending or, to the knowledge of the Company, threatened against the Company or its Subsidiaries, and no such entity has experienced any such labor strike, work stoppage, picketing, lockout, walkout or other organized work interruption during the past three (3) years. There are no labor unions or other organizations representing, purporting to represent and, to the knowledge of the Company, no union organization campaign is in progress with respect to, any employees of the Company and its Subsidiaries. There are no (i) unfair labor practice charges pending before the National Labor Relations Board or any other Governmental Authority, or (ii) material grievances, complaints, claims or judicial or administrative proceedings, in each case, which are pending or, to the knowledge of the Company, threatened by or on behalf of any employees. The Company and its Subsidiaries are in compliance in all material respects with all applicable laws, statutes, rules and regulations respecting employment and employment practices, terms and conditions of employment of employees, former employees and prospective employees, wages and hours, pay equity, discrimination in employment, wrongful discharge, collective bargaining, fair labor standards, occupational health and safety, personal rights or any other labor and employment-related matters. The Company and its Subsidiaries are not a party to, or otherwise bound by, any consent decree with, or citation any Governmental Authority relating to employees or employment practices. The Company and its Subsidiaries have properly classified all of their service providers as employed or self-employed, employees or independent contractors and as exempt or non-exempt for all purposes. During the three (3) years prior to the date of this Agreement, the Company and its Subsidiaries have not engaged in or effectuated any &#8220;plant closing&#8221; or employee &#8220;mass layoff&#8221; (in each case, as defined in the Worker Adjustment Retraining and Notification Act of 1988, as amended, or any similar state or local statute, rule or regulation) affecting any site of employment or one or more facilities or operating units within any site of employment or facility of any such entity.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;The Company and its Subsidiaries have paid in full to all of its employees or adequately accrued for in accordance with GAAP all wages, salaries, commissions, bonuses, benefits and other compensation due to or on behalf of such employees. There is no claim with respect to payment of wages, salary or overtime pay that has been asserted or is now pending or, to the knowledge of the Company, threatened before any Governmental Authority with respect to any Persons currently or formerly employed by the Company or its Subsidiaries.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;There are no material liabilities, whether contingent or absolute, of the Company or its Subsidiaries relating to workers&#8217; compensation benefits that are not fully insured against by a bona fide third-party insurance carrier. With respect to each Company Benefit Plan and with respect to each state workers&#8217; compensation arrangement that is funded wholly or partially through an insurance policy or public or private fund, all premiums required to have been paid to date under such insurance policy or fund have been.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">50</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.15&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Taxes</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Except as set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.15</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#58;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;The Company and its Subsidiaries have duly and timely filed or caused to be timely filed with the appropriate Tax Authority all Tax Returns required to be filed by, or with respect to, such entity. All such Tax Returns are true, complete and accurate in all material respects. Neither the Company nor any of its Subsidiaries is currently the beneficiary of any extension of time within which to file any Tax Return. No claim has ever been made by a Tax Authority in a jurisdiction where the Company or any of its Subsidiaries does not file a Tax Return that the Company or any of its Subsidiaries is or may be subject to taxation by that jurisdiction. All Taxes due and owing by the Company and its Subsidiaries (whether or not shown on any Tax Returns) have been timely paid. The Company and its Subsidiaries have withheld and paid all Taxes required to have been withheld and paid in connection with amounts paid or owing to any employee, independent contractor, creditor, stockholders of the Company or other Person.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;The unpaid Taxes of the Company and its Subsidiaries did not, as of the Company Balance Sheet Date, exceed the reserve for Tax liability (excluding any reserve for deferred Taxes established to reflect timing differences between book and Tax income) set forth on the face of the balance sheet included in the Interim Financial Statements (rather than in any notes thereto). Since the Company Balance Sheet Date, neither the Company nor any of its Subsidiaries has incurred any liability for Taxes outside the ordinary course of business or otherwise inconsistent with past custom and practice.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;No written agreement or other document waiving or extending, or having the effect of waiving or extending, the statute of limitations or the period of assessment or collection of any Taxes with respect to the Company and its Subsidiaries has been entered into. Neither the Company nor any of its Subsidiaries has granted to any Person any power of attorney with respect to any Tax matter relating to the Company or its Subsidiaries. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;No deficiencies for Taxes with respect to the Company or its Subsidiaries have been claimed, proposed or assessed by any Tax Authority. There are no pending or threatened audits, assessments or other actions for or relating to any liability in respect of Taxes of the Company or its Subsidiaries. No adjustment that would increase the Tax liability, or reduce any Tax asset, of the Company or any of its Subsidiaries has been made, proposed or threatened by a Tax Authority during any audit of any taxable period which would reasonably be expected to be made, proposed or threatened in an audit of any subsequent taxable period.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;Neither the Company nor any of its Subsidiaries (i) has received or applied for a Tax ruling or entered into a closing agreement pursuant to Section 7121 of the Code (or any predecessor provision or any similar provision of state, local or foreign Law), in either case that would be binding upon the Company or its Subsidiaries after the Closing Date, (ii) is or has ever been a member of any affiliated, consolidated, combined or unitary group for purposes of filing Tax Returns or paying Taxes or (iii) has any liability for the Taxes of any other Person (whether under Treasury Regulation Section 1.1502-6 or any similar provision of state, local or foreign Law, or as a transferee or successor, or pursuant to any Tax sharing, allocation or indemnity agreement or any other contractual agreements, or otherwise). None of the Company or any of its </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">51</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Subsidiaries is, or has ever been, a party to or bound by any Tax indemnity agreement, Tax sharing agreement, Tax allocation agreement or similar Contract. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(f)&#160;&#160;&#160;&#160;There are no Liens for Taxes upon any property or asset of the Company or its Subsidiaries (other than Permitted Liens).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(g)&#160;&#160;&#160;&#160;Neither the Company nor any of its Subsidiaries has been a party to any transaction that is or is substantially similar to a &#8220;reportable transaction&#8221; as such term is defined in Treasury Regulations Section 1.6011-4(b)(1), or any other transaction requiring disclosure under analogous provisions of state, local or foreign Tax Law.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(h)&#160;&#160;&#160;&#160;Neither the Company nor any of its Subsidiaries will be required to include any item of income in, or exclude any item of deduction from, taxable income for any period (or any portion thereof) ending after the Closing Date as a result of (i) any installment sale or other transaction prior to the Closing, (ii) the use of an incorrect method of accounting prior to the Closing, (iii) any accounting method change or agreement with any Tax Authority filed or made prior to the Closing, (iv) any prepaid amount received prior to the Closing, (v) any closing agreement or other agreement with a Tax Authority prior to the Closing, (vi) any election under Section 108(i) of the Code, or (vii) an election under Section 965 of the Code.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(i)&#160;&#160;&#160;&#160;All books and records relating to Taxes (including related work papers) have been adequately maintained for all periods for which the statute of limitations remains open.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(j)&#160;&#160;&#160;&#160;Neither the Company nor any of its Subsidiaries has engaged in a trade or business, had a permanent establishment (within the meaning of an applicable Tax treaty), or otherwise has become subject to Tax jurisdiction in a country other than the country of its formation.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(k)&#160;&#160;&#160;&#160;All transfer pricing rules have been complied with. All documentation required by all relevant transfer pricing laws has been timely prepared, and complete and accurate copies of such documentation have been made available to Buyer. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(l)&#160;&#160;&#160;&#160;Neither the Company nor any of its Subsidiaries (or any predecessors thereof) has been a party to any transaction intended to qualify under Section 355 of the Code.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(m)&#160;&#160;&#160;&#160;Neither the Company nor any of its Subsidiaries owns an interest in real property in any jurisdiction (i) in which a material amount of Tax is imposed, or the value of the interest is materially reassessed, on the transfer of an interest in real property resulting from the transactions contemplated by this Agreement and (ii) which treats the transfer of an interest (resulting from the transactions contemplated by this Agreement) in an entity that owns an interest in real property as a transfer of the interest in real property.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(n)&#160;&#160;&#160;&#160;Neither the Company nor any of its Subsidiaries has participated in or cooperated with, or has agreed to participate in or cooperate with, or is participating in or cooperating with, any international boycott within the meaning of Section 999 of the Code.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">52</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(o)&#160;&#160;&#160;&#160;Seller has provided or made available to Purchase Representative all documentation relating to, and is in full compliance with all terms and conditions of, any Tax exemption, Tax holiday, Tax incentive or other Tax reduction agreement or order of a territorial or non-U.S. government. The consummation of the transactions contemplated by this Agreement will not have any adverse effect on the continued validity and effectiveness of any such Tax exemption, Tax holiday, Tax incentive or other Tax reduction agreement or order.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.16&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Brokers&#8217; Fees</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. No broker, finder, investment banker or other Person is entitled to any brokerage fee, finders&#8217; fee or other similar commission, for which Buyer or the Company or any of its Subsidiaries would be liable in connection with the transactions contemplated by this Agreement based upon arrangements made by the Company or any of its Affiliates.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.17&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Insurance</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.17</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth a list of (a) all policies of property, fire and casualty, product liability, workers&#8217; compensation, and other forms of insurance held by, or for the benefit of, the Company or any of its Subsidiaries. True and complete copies of such insurance policies have been made available to Buyer or its representatives. Neither Company nor its Subsidiaries have received any written notice from any insurer under any such insurance policies, canceling or materially adversely amending any such policy or denying renewal of coverage thereunder and (b) all premiums on such insurance policies due and payable have been paid.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.18&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Licenses, Permits and Authorizations</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The Company and its Subsidiaries hold free and clear of all Liens (other than Permitted Liens), and is in compliance with, all of the licenses, approvals, authorizations, clearances, consents, registrations and permits issued by Governmental Authorities, including the FDA, that are (a) used in the conduct of the businesses of the Company and its Subsidiaries as currently conducted or (b) required by applicable Laws to permit the Company and its Subsidiaries to own, operate, use and maintain their assets in the manner in which they are now operated, used and maintained or to conduct the businesses of the Company and its Subsidiaries as currently conducted, including the manufacture, production, distribution, marketing, performance, sale or support of any Regulated Product (collectively, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Permits</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.18</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth a complete list of such Permits held by the Company and its Subsidiaries as of the date hereof.&#160;Accurate and complete copies of such Permits have been made available to Buyer. The Company and its Subsidiaries have fulfilled and performed all of its material obligations that have accrued with respect to the all such Permits, and to the knowledge of the Company at the date of this Agreement, no event has occurred which allows, or after notice or lapse of time would allow, revocation or termination thereof or results in any other material impairment of the rights of the holder of any Permit. There are no pending or, to the knowledge of the Company at the date of this Agreement, threatened Actions before or by any Governmental Authority alleging that any operation or activity of the Company or its Subsidiaries is in violation of any applicable Law or that would reasonably be expected to result in the cancellation, revocation or termination of any such Permit.&#160;Such Permits will not be adversely affected by the consummation of the transactions contemplated by this Agreement.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">53</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.19&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Real Property</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.19</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth a list of all Leased Real Property. The Company (i) has a valid and enforceable leasehold estate in, and enjoys peaceful and undisturbed possession of, all Leased Real Property, subject to the Remedies Exception and any Permitted Liens and (ii) has not received any written notice from any lessor of such Leased Real Property of, nor does the Company have knowledge of the existence of, any default, event or circumstance that, with notice or lapse of time, or both, would constitute a material default by the party that is the lessee or lessor of such Leased Real Property.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;None of the Company or any of its Subsidiaries own, nor have they ever owned, any real property.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.20&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Intellectual Property</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.20(a)(i)</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth, for the Company and the Teneo Subsidiaries, (i) a list of all registrations and applications for registrations included in the Owned Intellectual Property Rights, including for each item (A) the record owner (and name of any other Person with an ownership interest in such item of Owned Intellectual Property Rights, if any), jurisdiction (or, with respect to Domain Names, the applicable registrar), status, date and registration or application number of each item, as applicable, (B) the name of the record owner and any other Person that has an ownership interest in such item of Owned Intellectual Property Rights other than security interests expressly disclosed elsewhere on the Disclosure Schedules as being applicable to such Owned Intellectual Property Rights, and the nature of such ownership interest, and (C) any actions that are required to be taken by Company or any of the Teneo Subsidiaries within one hundred and eighty (180) days of the date of this Agreement, including the payment of any registration, maintenance or renewal fees or the filing of or response to any documents, applications or certificates, for the purposes of prosecuting, obtaining, perfecting, maintaining or renewing any Owned Intellectual Property Rights, and (ii)&#160;a true and complete list of all material unregistered marks of the Company or the Teneo Subsidiaries included in the Owned Intellectual Property Rights. With respect to all registrations and applications for registration of Owned Intellectual Property Rights set forth on </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.20(a)(i)</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, except as set forth on </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.20(b)</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, the Company or a Teneo Subsidiary has filed all statements of use and paid all renewal and maintenance fees, annuities and other fees with respect thereto that are due or payable as of the date of this Agreement. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.20(b)(i)</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth, for the Excluded Entities, (i) a list of all registrations and applications for registrations included in any and all Intellectual Property Rights owned or purported to be owned by any of the Excluded Entities (the &#8220;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Excluded Entities Owned Intellectual Property Rights</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), including for each item (A) the record owner (and name of any other Person with an ownership interest in such item of Excluded Entities Owned Intellectual Property Rights, if any), jurisdiction (or, with respect to Domain Names, the applicable registrar), status, date and registration or application number of each item, as applicable, and (B) the name of the record owner and any other Person that has an ownership interest in such item of Excluded Entities Owned Intellectual Property Rights other than security interests expressly </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">54</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">disclosed elsewhere on the Disclosure Schedules as being applicable to such Excluded Entities Owned Intellectual Property Rights, and the nature of such ownership interest. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.20(c)</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth a list of any Patents used in, held for use in or necessary for the conduct of both (i) the Business, and (ii) the Excluded Businesses, in each case, as currently conducted or proposed to be conducted (the &#8220;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Shared Intellectual Property</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Except as set forth on </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.20(d)(i)</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, the Company or one of its Subsidiaries (i) exclusively owns all right, title, and interest in, to and under all Owned Intellectual Property Rights</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">free and clear of all Liens (other than Permitted Liens), and (ii) owns or has the right to use pursuant to license, sublicense, agreement or permission, all other Intellectual Property Rights used in the operation of the business(es) of the Company and its Subsidiaries. Except as set forth on </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.20(d)(ii)</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, neither the Company nor any of its Subsidiaries has transferred ownership of (whether a whole or partial interest), or granted any exclusive right to use, any Company Intellectual Property to any Person. No Person that has licensed any Licensed Intellectual Property Rights to the Company or its Subsidiaries has ownership, license or other rights to derivative works or improvements made by or on behalf of Company or its Subsidiaries related to such Licensed Intellectual Property Rights. All employees, contractors and consultants of the Company or any of its Subsidiaries who have contributed to the creation, discovery, reduction to practice or development of the Company&#8217;s or such Subsidiary&#8217;s products or services or any Owned Intellectual Property Rights have executed written instruments with the Company or the applicable Subsidiary that presently assign to the Company or such Subsidiary all right, title and interest in and to and under any and all Intellectual Property Rights developed in the performance of services for the Company or such Subsidiary (&#8220;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">IP Assignments</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). No Owned Intellectual Property Right is owned, licensed to or otherwise held by a current or former employee, officer, director, manager, consultant or contractor of the Company or any of its Subsidiaries. To the knowledge of the Company, no employee of the Company or any of its Subsidiaries is (i) bound by or otherwise subject to any Contract restricting him or her from performing his or her duties for the Company or its applicable Subsidiary, or (ii) in breach of any Contract with any former employer or other Person concerning Intellectual Property Rights or confidentiality due to his or her activities as an employee of the Company or any of its Subsidiaries. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">The Company or its Subsidiaries exclusively owns or has a valid and enforceable license to use all Intellectual Property Rights used in, held for use in or necessary to operate the Business as currently conducted and currently proposed to be conducted, including, to the knowledge of the Company and its Subsidiaries, the research, development, manufacturing and commercialization of the Preclinical Company Milestone Candidates. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(f)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Neither the Company nor any of its Subsidiaries has taken or failed to take any action that would be reasonably expected to result in the abandonment, invalidity, cancellation, forfeiture, relinquishing, invalidation or unenforceability of any Owned Intellectual Property Right (including with respect to any Trademark, a failure to exercise adequate quality controls or an assignment in gross without the accompanying goodwill) or any Licensed Intellectual Property Rights during, with respect to such Licensed Intellectual Property Rights, the period for </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">55</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">which the Company or any one of its Subsidiaries has been responsible for prosecuting. Each of the Patents included in the Owned Intellectual Property Rights and any Licensed Intellectual Property Rights for which the Company or any one of its Subsidiaries has been responsible for prosecuting properly identifies each and every inventor of the claims thereof as determined in accordance with the applicable laws of the jurisdiction in which such Patent is issued or pending. Neither the Company nor any of its Subsidiaries has engaged in Patent or Copyright misuse or any fraud or inequitable conduct in connection with any Company Intellectual Property. Each of the Company and its Subsidiaries and their respective patent counsel have complied with its duty of candor and disclosure and have made no material misrepresentations in the filings submitted to the applicable Governmental Authorities with respect to all Patents included in the Owned Intellectual Property Rights and any Licensed Intellectual Property Rights for which the Company or any one of its Subsidiaries has at any time been responsible for prosecuting. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(g)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">There exist no material restrictions on the disclosure, use, license or transfer of the Owned Intellectual Property Rights.  There exist no material restrictions on the disclosure, use, license or transfer of the Licensed Intellectual Property Rights that has been imposed upon Company or its Subsidiaries pursuant to a Contract to which the Company of a Subsidiary is a party. Neither the execution, delivery and performance of this Agreement or any of the other Transaction Documents nor the consummation of the transactions contemplated hereby or thereby will (i) result in the release, disclosure or delivery of any Owned Intellectual Property Rights by or to any escrow agent or other third party&#59; (ii) result in the grant, assignment or transfer to any other third party of any license or other right or interest under, to or in any of the Owned Intellectual Property Rights&#59; (iii) result in Company or any of its Subsidiaries being bound by or subject to any exclusivity obligations, non-compete or other restrictions on the operation or scope of their respective businesses, or to any obligation to grant any rights in or to any of Company&#8217;s or its Subsidiaries&#8217; technology or Intellectual Property Rights&#59; or (iv) result in any third party having the right to cause any of the foregoing. The Company or one of its Subsidiaries will continue to own or have after the Closing Date valid rights or licenses as are sufficient to use all of the Company Intellectual Property used by the Company or its Subsidiaries to the same extent as prior to the Closing.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(h)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">To the knowledge of the Company, the Company&#8217;s and its Subsidiaries&#8217; Regulated Products, including the use, manufacture, and marketing of such products, and the conduct by the Company and its Subsidiaries of their respective businesses as currently conducted and as currently proposed by the Company and its Subsidiaries, does not infringe upon, dilute, misappropriate or otherwise violate any Intellectual Property Rights of any third Person, including any Excluded Entity (regardless of any exemption from patent infringement under 35 U.S.C. 271(e)(1) or any similar exceptions outside the United States). Except as set forth on </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule&#160;4.20(h)</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, the Company and its Subsidiaries have not received from any Person in the past seven (7) years any written notice, charge, complaint, claim or other written assertion of (i)&#160;any infringement, dilution, violation or misappropriation of any Intellectual Property Rights of any Person, including cease and desist letters and offers to take a license, (ii) based upon, or challenging or seeking to deny or restrict, the rights of the Company or its Subsidiaries in any Company Intellectual Property, or (iii) an allegation that any Company Intellectual Property is invalid or unenforceable. No infringement, misappropriation, or similar claim or legal </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">56</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">action is pending or to the knowledge of the Company at the date of this Agreement, has been threatened against any Person who may be entitled to be indemnified by the Company or its Subsidiaries under a Contract with the Company or its Subsidiaries with respect to such claim. This </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section&#160;4.20(h)</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth the only representation or warranty of Company or any of its Subsidiaries with respect to the violation of Intellectual Property Rights.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(i)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">To the knowledge of the Company, no third party is infringing upon, misappropriating or otherwise violating any Intellectual Property owned by or exclusively licensed to the Company or any of its Subsidiaries. Within the past twenty-four (24) months prior to the date of this Agreement, neither the Company nor any of its Subsidiaries has sent any written notice, charge, complaint, claim or other written assertion asserting or threatening to assert any Action against any Person involving or relating to any Intellectual Property owned by or exclusively licensed to the Company or any of its Subsidiaries.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(j)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">The Company and its Subsidiaries have taken commercially reasonable security measures and reasonable actions to, and have maintained policies and processes to, protect and maintain the secrecy and prevent the unauthorized disclosure or use of all confidential or non-public information, know-how, source code and trade secrets owned or controlled by the Company or its Subsidiaries (&#8220;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Confidential Information</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(k)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.20(k)(i)</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth a complete and accurate list of all written agreements under which a third party grants to the Company or any of its Subsidiaries a license under or other right, title or interest in or to (including a covenant not to be sued or right to enforce or prosecute any Patents, or any right of first refusal or similar right to acquire exclusive rights or ownership) any Intellectual Property Rights, other than (i) validly executed invention assignment agreements with former or current employees based on forms that have been made available to the Company, or (ii) licenses for off-the-shelf software (the &#8220;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Licenses In</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule&#160;4.20(k)(ii)</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth a complete and accurate list of all written agreements under which the Company or any of its Subsidiaries grants or is obligated to grant to any third party a license under or other right, title or interest in or to (including a covenant not to be sued or right to enforce or prosecute any Patents, or any right of first refusal or similar right to acquire exclusive rights or ownership) any Company Intellectual Property (the &#8220;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Licenses Out</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). </font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule&#160;4.20(k)(iii)</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> sets forth a complete and accurate list of all written agreements under which the Company, any of its Subsidiaries, or a third party grants or is obligated to grant to Excluded Entities a license under or other right, title or interest in or to (including a covenant not to be sued or right to enforce or prosecute any Patents, or any right of first refusal or similar right to acquire exclusive rights or ownership) any Company Intellectual Property, other than (i)&#160;validly executed invention assignment agreements with former or current employees based on forms that have been made available to the Company, or (ii) licenses for off-the-shelf software (the &#8220;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Excluded Entity Licenses</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; and, collectively with the Licenses In and the Licenses Out, the &#8220;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">IP Licenses</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). The Company has provided a complete and correct copy of each IP License, including all modifications, amendments and supplements thereto.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(l)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">None of the Owned Intellectual Property Rights, and to the knowledge of the Company and its Subsidiaries, no Licensed Intellectual Property Rights, were developed using </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">57</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">any federal, state, government, non-profit, university or institutional funding, facilities, personnel or resources, and no such funding was used in connection with the discovery, design, identification, research or development of any Regulated Products or Eligible Programs by the Company or its Subsidiaries. No such entity or institution (i) owns or otherwise holds, or has the right to obtain, any rights to any Owned Intellectual Property Rights and&#47;or to the knowledge of the Company and its Subsidiaries, to any Licensed Intellectual Property Rights, (ii) has imposed or purported to impose, or has the right, whether contingent or otherwise, to impose, any obligations or restrictions on the Company or its Subsidiaries with respect to the licensing or granting of any Owned Intellectual Property Rights or to the knowledge of the Company and its Subsidiaries, any Licensed Intellectual Property Rights or the manufacture or commercialization of any product or service developed or created by the Company or its Subsidiaries, or (iii) is or may become entitled to receive any royalties or other payments from the Company or its Subsidiaries.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(m)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Each of the Company and its Subsidiaries is in compliance in all material respects with all licenses for Open Source Software that it uses in the business of the Company or its Subsidiaries as presently conducted, including attribution and copyright notice requirements and the material proprietary software included in the Owned Intellectual Property Rights that is distributed or made available to third parties is not subject to any license that requires the distribution or availability of proprietary source code under such circumstances. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(n)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">No Person (other than employees or Persons working on behalf of the Company and subject to reasonable confidentiality arrangements) has the current or contingent right to access or possess any material source code included in the Owned Intellectual Property Rights.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(o)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">The IT Assets are sufficient for the conduct of the business of the Company and its Subsidiaries as currently conducted. The Company and is Subsidiaries have taken commercially reasonable measures to preserve and maintain the performance, security and integrity of the IT Assets against any unauthorized use, access, interruption, modification or corruption, including (i) commercially reasonable physical, technical and administrative controls, policies, procedures, and safeguards to maintain and protect the integrity, continuous operation, redundancy and security of the IT Assets and (ii) commercially reasonable disaster recovery plans, procedures and facilities for the business of the Company and its Subsidiaries. The Company and its Subsidiaries have used commercially reasonable efforts to implement security patches or upgrades available and necessary to protect the IT Assets.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.21&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Environmental Matters</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The Company and its Subsidiaries are in compliance and have complied with all Environmental Laws except for any such instance of noncompliance that would not reasonably be expected to result in material liability of the Company or any of its Subsidiaries. The Company has timely applied for, holds, and is in material compliance with, all licenses, approvals, consents, registrations and permits required under applicable Environmental Laws to permit the Company and its Subsidiaries to own, operate use and maintain their respective assets in a manner in which it is now operated, used and maintained and to conduct the businesses of the Company and its Subsidiaries as currently conducted, except where the failure to timely apply, the absence of, or the failure to be in material compliance with, any such </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">58</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">permit would not reasonably be expected to result in a material liability of the Company or any of its Subsidiaries. There are no written claims, legal or regulatory proceedings or actions, or notices of violation or liability pending or, to the knowledge of the Company, threatened against the Company or any of its Subsidiaries alleging violations of or liability under any Environmental Law or with respect to Hazardous Materials and there has been no Release that would reasonably be expected to result in material liability of the Company or any of its Subsidiaries. The Company has made available to Buyer copies of all environmental assessments, permits, reports, audits and other material documents in its possession or under its control that relate to Company&#8217;s and its Subsidiaries&#8217; compliance with or liability under Environmental Laws or the environmental condition of any real property that the Company or its Subsidiaries currently or formerly has owned, operated or leased. </font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.22&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Absence of Changes</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;From the Company Balance Sheet Date to the date of this Agreement, there has not been any Material Adverse Effect.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;Except as expressly contemplated by this Agreement, from the Company Balance Sheet Date through the date of this Agreement, the Company and its Subsidiaries have, in all material respects, conducted its business and operated its properties in the ordinary course of business consistent with past practice.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;From the Company Balance Sheet Date through the date of this Agreement, there has been no action taken by the Company or its Subsidiaries which, if taken after the date of this Agreement without Buyer&#8217;s consent, would violate the provisions of </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 6.1(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.23&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Affiliate Matters</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. (a) No Related Person has any direct or indirect interest in any material asset used in the business of the Company or its Subsidiaries as currently conducted&#59; (b) no Related Person is indebted to the Company or its Subsidiaries&#59; (c) no Related Person has entered into, or has had any direct or indirect financial interest in, any contract entered into by the Company or its Subsidiaries or other business arrangement involving the Company or its Subsidiaries&#59; (d)&#160;neither the Company nor its Subsidiaries have any claims, causes of action or other Liability to or by any Related Person, in each case, other than pursuant to any agreement relating to the employment of any employee or consultant of the Company, the indemnification of any director or officer of the Company or its Subsidiaries, any benefit plan or any agreement set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.23</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and (e) to the knowledge of the Company, no consultant or other independent contractor providing services to the Company or its Subsidiaries has any direct or indirect interest (including any Equity Interest or other financial interest) in, or receives any form of compensation from, any Related Person. For purposes of this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.23</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, each of the following shall be deemed a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Related Person</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;&#58; (i)&#160;each individual who is an officer, director or employee of the Company&#59; (ii) each Pre-Closing Holder who owns of record in excess of five percent (5%) of the outstanding Company Capital Stock on a fully diluted basis&#59; (iii) each member of the immediate family of each of the individuals referred to in clauses (i) and (ii) above, where &#8220;immediate family&#8221; shall mean such individual&#8217;s spouse and minor children living in such individual&#8217;s home and (iv) any trust or other entity, other than the Company, in which any one of the individuals referred to in clauses (i), (ii) and (iii) above holds, or in which more </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">59</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">than one of such individuals collectively hold, beneficially or otherwise, a material voting, proprietary, equity or other financial interest.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.24&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Books and Records</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The Company has made and kept (and given Buyer access or made available to) true, correct and complete books and records and accounts, which, in reasonable detail, accurately and fairly reflect the activities of the Company and its Subsidiaries. The minute books of the Company previously made available to Buyer were true and correct and accurately and adequately reflect in all material respects all actions taken on behalf of the Company and its Subsidiaries by its stockholders and board of directors (including any committee thereof). The share certificate books and transfer ledgers of the Company and its Subsidiaries previously made available to Buyer are true, correct and complete, and accurately reflect all transactions effected in the Shares of the Company and its Subsidiaries through and including the date hereof.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.25&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Certain Business Practices</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Neither the Company, its Subsidiaries, nor any of their respective owners, directors, officers, agents, employees, representatives, subcontractors, or other third parties acting for or on behalf of the Company or any of its Affiliates has, in each case in connection with the Company&#8217;s or its Subsidiaries&#8217; businesses, either directly or indirectly, offered, authorized, made, agreed to make, or otherwise used any funds or other transfer of value in connection with any (a) unlawful contributions, gifts, entertainment or other unlawful expenses, including expenses related to political activity, (b) unlawful payment to foreign or domestic government officials or employees or to foreign or domestic political parties or campaigns, (c) bribes or kickback payments, or otherwise taken any action that would constitute a violation of any provision of Anti-Corruption Laws, (d) payment to any customer or supplier of the Company or any of its Subsidiaries, or have given any other consideration to any such customer or supplier in respect of the Company&#8217;s or its Subsidiaries&#8217; businesses, that violates applicable Law or (e) other unlawful payment, offer, or expense.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.26&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">No Debarment</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Neither the Company, its Subsidiaries, nor any officer, director, consultant, employee, manager or agent acting for or on their behalf, has been, nor to the knowledge of the Company, has the Company or its Subsidiaries otherwise used in any capacity any Person who has been, (a)&#160;debarred under 21 U.S.C. &#167; 335a or any similar state or foreign Law, (v) excluded from participation in federal health care programs under 42 U.S.C. &#167;&#167; 1320a-7, 1320a-7a or any similar state or foreign applicable Law, (c) disqualified by any Governmental Authority, (d) suspended or otherwise determined to be or identified as ineligible to participate in any health care contracting program of any Governmental Authority, or (e) convicted of, charged with, investigated for or engaged in any conduct that would reasonably be expected to result in such debarment, exclusion, disqualification, suspension, or ineligibility. No debarment, exclusion or disqualification proceedings or investigations are pending or to the knowledge of the Company, threatened against the Company, its Subsidiaries, or any officer, director, consultant, employee, manager or agent acting for or on behalf of the Company. No proceedings are pending or to the knowledge of the Company, threatened that would reasonably be expected to result in criminal liability, debarment, disqualification, or exclusion by any Governmental Authority.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">60</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.27&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Termination of Certain Agreements</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:7.8pt;font-weight:400;line-height:120%;position:relative;top:-4.2pt;vertical-align:baseline"> </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;Each Investment Agreement shall, by its respective terms, automatically terminate, as of, or immediately prior to, the Closing.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;The Contracts set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule&#160;4.27</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall terminate as of, or immediately prior to, the Closing.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.28&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Funded Debt</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. None of the Company or any of its Subsidiaries (a) is a guarantor of any indebtedness of any other person, firm or corporation or (b) has any Funded Debt of any kind whatsoever, whether accrued, contingent, absolute, determined, determinable or otherwise, and there is no existing condition, situation or set of circumstances which would reasonably be expected to result in such a liability or debt. </font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.29&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Data Privacy and Security</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;The Company and its Subsidiaries are, and have at all times been, in compliance with (i) Privacy Laws, (ii) Contracts (or portions thereof) between the Company or its Subsidiaries and distributors of the Company products, visitors to the Company&#8217;s websites, vendors and other Persons relating to Personal Data and (iii) the Company&#8217;s and its Subsidiaries&#8217; internal and external privacy policies and any other public statements or representations made by the Company or its Subsidiaries ((i), (ii) and (iii) together, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Privacy Commitments</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). The Company and its Subsidiaries currently make, and have at all times made, available to individuals privacy policies and such policies are, and have at all times been accurate, complete, not misrepresentative (including by omission) of the Company&#8217;s or its Subsidiaries&#8217; practices, as applicable, in relation to Personal Data. The execution, delivery, or performance of this Agreement or the consummation of any of the transactions contemplated by this Agreement (i) do not require the delivery of any notice to or consent from any Person relating to Personal Data and (ii) will not conflict with or violate any Privacy Commitments and (iii) will not prohibit the transfer of Personal Data to Buyer. For the avoidance of doubt, to the extent Personal Data held or controlled by the Company is &#8220;personal information&#8221; under the CCPA, such data is an asset as contemplated by Section 1798.140(t)(2)(D).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;To the extent required by applicable Privacy Laws, the Company has a record of Personal Data processing activities under the Company&#8217;s or its Subsidiaries&#8217; responsibility. The Company and its Subsidiaries have, and at all times have had, processes in place to ensure their products and processing of Personal Data comply in all material respects with data protection by design and default and data minimization including data retention schedules as required by Privacy Laws.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;The Company and its Subsidiaries have maintained administrative, physical and technical safeguards to protect the confidentiality, integrity and security of Personal Data against any unauthorized control, use, access, interruption, modification, deletion or corruption, including disaster recovery plans, data backup, data storage and system redundancy procedures and facilities that are consistent with the practices of similarly situated companies in the industry of the Company, and takes and has taken commercially reasonable steps to safeguard and back-</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">61</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">up the Personal Data at secure off-site locations. The Company and its Subsidiaries have, and at all times have had, Contracts in place with all vendors or other Persons whose relationship with the Company or its Subsidiaries involves such Person processing Personal Data for or on behalf of the Company or its Subsidiaries, which Contracts require such Persons and their subcontractors to, at minimum (i) implement and maintain administrative, physical and technical safeguards to protect the confidentiality, integrity and security of Personal Data and computer systems on or through which any Personal Data are stored, transmitted or otherwise processed by such Person(ii) protect and process such Personal Data consistent with the Company&#8217;s or its Subsidiaries&#8217; Privacy Commitments, as applicable, and (iii) notify Company or a Subsidiary of the Company of any data security breaches relating to such Personal Data. To the knowledge of the Company at the date of this Agreement, such Persons have not breached any such privacy-related obligations in their Contracts.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;To the knowledge of the Company and its Subsidiaries, there has been no data security breach or any other unauthorized access, use or disclosure of any Personal Data owned, used, stored, or controlled by or on behalf of the Company or any of its Subsidiaries, including any such incident that would constitute a breach for which notification to individuals or any Governmental Authority is required under Privacy Commitments and no such breach is threatened or suspected.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;Except as disclosed on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.29(e)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, neither the Company nor any of its Subsidiaries have received any notice of, or been charged with, the violation of any Privacy Commitments, and there are no pending notices or Actions, of the Company or any of its Subsidiaries by any Governmental Authority relating to Privacy Commitments, or civil actions against the Company alleging any violation of Privacy Commitments. To the knowledge of the Company at the date of this Agreement, there are no facts, circumstances or conditions that would reasonably be expected to form the basis for any notice or Action against or affecting the Company, its Subsidiaries or any of their respective officers, directors, managers, managing directors or employees relating to or arising under Privacy Commitments.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.30&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">No Outside Reliance</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Notwithstanding anything contained in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article IV</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or any other provision hereof, each of the Company and the Stockholder Representative acknowledges and agrees that neither Buyer nor Merger Sub nor any of their respective Affiliates, nor any of its or their respective directors, officers, employees, stockholders, partners, members, agents or representatives, has made, or is making, any representation or warranty whatsoever, express or implied (and neither the Company nor the Stockholder Representative has relied on any representation, warranty or statement of any kind by Buyer or Merger Sub or any of their respective Affiliates or any of their respective directors, officers, employees, stockholders, partners, members, agents or representatives), beyond those expressly given in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article V</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.&#160;Without limiting the generality of the foregoing, it is understood that any plans, projections or other predictions, as well as any information, documents or other materials or presentations that have been or shall hereafter be provided to the Company or any of its Affiliates, agents or representatives are not and will not be deemed to be representations or warranties of the Buyer or Merger Sub and no representation or warranty is made as to the accuracy or completeness of any of the foregoing.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">62</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 4.31&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">No Additional Representations or Warranties</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Except as provided in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article&#160;IV</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, neither the Company nor any of its Affiliates, nor any of their respective directors, officers, employees, stockholders, partners, members or representatives has made, or is making, any representation or warranty whatsoever to Buyer or Merger Sub or their respective Affiliates, respective directors, officers, employees, stockholders, partners, members or representatives, and no such party shall be liable in respect of the accuracy or completeness of any information provided to Buyer or Merger Sub or their respective Affiliates, directors, officers, employees, stockholders, partners, members or representatives.</font></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">ARTICLE V.<br>REPRESENTATIONS AND WARRANTIES OF BUYER AND MERGER SUB</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Except as set forth in the Disclosure Schedules, Buyer and Merger Sub represent and warrant to the Company as of the date of this Agreement and as of the Closing Date as follows (it being understood that each representation and warranty that calls for disclosure as contained in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article V</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> is subject to (a) the exceptions and disclosures set forth in the section or subsection of the Disclosure Schedules corresponding to the particular section or subsection in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article V</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> in which such representation and warranty appears&#59; and (b) any exceptions or disclosures disclosed in any other section or subsection of the Disclosure Schedules to the extent that it is reasonably apparent, upon reading such disclosure, that the disclosure is responsive to such other section or subsection of this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article V</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and such representation and warranty calls for disclosure)&#58; </font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 5.1&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Corporate Organization</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Buyer has been duly incorporated and is validly existing as a corporation in good standing under the Laws of the State of Delaware. Merger Sub has been duly incorporated and is validly existing as a corporation in good standing under the Laws of the State of Delaware. Buyer owns, beneficially and of record, all of the outstanding shares of capital stock of Merger Sub, free and clear of all Liens, other than applicable restrictions under applicable securities Laws.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 5.2&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Due Authorization</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Each of Buyer and Merger Sub has all requisite power and authority to execute and deliver this Agreement and (subject to the consents, approvals, authorizations and other requirements described in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 5.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">) to consummate the Merger and the other transactions contemplated hereby. The execution and delivery of this Agreement by Buyer and Merger Sub and the consummation by them of the transactions contemplated hereby have been duly and validly authorized and approved by the Board of Directors of each of Buyer and Merger Sub. This Agreement has been duly and validly executed and delivered by each of Buyer and Merger Sub and assuming this Agreement constitutes a legal, valid and binding obligation of the Company and the Stockholder Representative, this Agreement constitutes a legal, valid and binding obligation of each of Buyer and Merger Sub, enforceable against Buyer and Merger Sub in accordance with its terms, subject to the Remedies Exception.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 5.3&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">No Conflict</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Assuming the making of all designations, declarations or filings with any Governmental Authority as described in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 5.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and the receipt of all consents, approvals or authorizations of any Governmental Authority as described in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 5.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, the execution and delivery of this Agreement by Buyer and Merger Sub and the consummation by them of the transactions contemplated hereby do not and will not, as of the Closing, (a) violate </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">63</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">any provision of, or result in the breach of any applicable Law to which Buyer or Merger Sub is subject, (b) conflict with the certificate of incorporation, bylaws or other organizational documents of Buyer or Merger Sub, or (c) violate any provision of or result in a breach of any material agreement to which Buyer or Merger Sub is a party.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 5.4&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Governmental Consents</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Assuming the truth and completeness of the representations and warranties of the Company contained in this Agreement, no consent, approval or authorization of, or designation, declaration or filing with, any Governmental Authority is required on the part of Buyer or Merger Sub with respect to Buyer&#8217;s or Merger Sub&#8217;s execution or delivery of this Agreement or the consummation by Buyer or Merger Sub of the transactions contemplated hereby, except for (a) applicable requirements of the HSR Act or any similar foreign Law and filing of the Merger with the Secretary of the State of Delaware, (b) compliance with any applicable securities Laws, and (c) any consents, approvals, authorizations, designations, declarations or filings which if not obtained or made, would not materially impair Buyer&#8217;s ability to consummate the Merger.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 5.5&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Financial Ability</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Buyer and&#47;or Merger Sub have sufficient funds available to consummate the transactions contemplated by this Agreement</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 5.6&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Brokers&#8217; Fees</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. No broker, finder, investment banker or other Person is entitled to any brokerage fee, finders&#8217; fee or other similar commission in connection with the transactions contemplated by this Agreement based upon arrangements made by Buyer or any of its Affiliates.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 5.7&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">No Additional Representations or Warranties</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Except as provided in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article&#160;V</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, neither the Buyer, Merger Sub nor any of their respective Affiliates, nor any of their respective directors, officers, employees, stockholders, partners, members or representatives has made, or is making, any representation or warranty whatsoever to the Company or its Affiliates, nor any of their respective directors, officers, employees, stockholders, partners, members or representatives, and no such party shall be liable in respect of the accuracy or completeness of any information provided to the Company or its respective Affiliates, directors, officers, employees, stockholders, partners, members or representatives.</font></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">ARTICLE VI.<br>COVENANTS OF THE COMPANY</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.1&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Conduct of Business</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;From the date of this Agreement until the earlier to occur of the Effective Time and the termination of this Agreement pursuant to and in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 10.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Period</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), except as set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 6.1(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, as required by applicable Law or as specifically consented to in writing by Buyer, the Company shall carry on its business in the ordinary course of business consistent with past practice. and, to the extent consistent with such business, preserve intact the present business of the Company and its Subsidiaries, use commercially reasonable efforts to keep available the services of the current Employees of and consultants to the Company and its Subsidiaries, use commercially reasonable efforts to preserve </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">64</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">the assets (including intangible assets) and properties of the Company and its Subsidiaries, and use commercially reasonable efforts to preserve the relationships of the Company and its Subsidiaries with those customers, suppliers, distributors, licensors, licensees, and others having material business dealings with them, all with the goal of preserving unimpaired the goodwill and ongoing businesses of the Company and its Subsidiaries at the Effective Time.  </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;In addition, without limiting the generality of </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 6.1(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, during the Pre-Closing Period, except as set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 6.1(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, as required by applicable Law or as specifically consented to in writing by Buyer (which consent shall not be unreasonably withheld, conditioned or delayed), the Company shall not, except to the extent expressly provided otherwise in this Agreement, do any of the following&#58;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(i)&#160;&#160;&#160;&#160;change or amend the Company Charter, Company Bylaws or other organizational documents of the Company, or its Subsidiaries except as otherwise required by Law or as contemplated by the Restructuring&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(ii)&#160;&#160;&#160;&#160;authorize for issuance, issue, grant, sell, deliver, dispose of, pledge or otherwise encumber any Equity Interests of the Company or its Subsidiaries, except for issuances contemplated on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 6.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or of shares of Common Stock upon the exercise of outstanding Company Options, except as contemplated by the Restructuring&#59; </font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(iii)&#160;&#160;&#160;&#160;authorize, approve, declare, set aside or pay any dividend or other distribution, payable in cash, stock, property or otherwise, in respect of the Company Capital Stock or the Equity Interests of the Company&#8217;s Subsidiaries, except as contemplated by the Restructuring&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(iv)&#160;&#160;&#160;&#160;acquire any Equity Interests of any other Person, other than as contemplated by the Restructuring&#59; </font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(v)&#160;&#160;&#160;&#160;adopt a plan of complete or partial liquidation or dissolution, recapitalization or other reorganization, except as contemplated by the Restructuring&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(vi)&#160;&#160;&#160;&#160;split, combine or reclassify the outstanding shares of Company Capital Stock nor enter into any agreement with respect to voting of any of the Company Capital Stock&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(vii)&#160;&#160;&#160;&#160;(A) modify, amend or terminate (excluding any expiration in accordance with its terms) any Contract of a type required to be listed on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule&#160;4.12</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or any material insurance policy required to be listed on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule&#160;4.17</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, or (B) enter into any Contract of a type that would be required to be listed on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.12</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> if such Contract was in effect on the date hereof&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(viii)&#160;&#160;&#160;&#160;sell, assign, transfer, convey, lease, license, guarantee, mortgage, pledge, encumber or otherwise dispose of any material assets or properties, except in the ordinary course of business&#59;</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">65</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(ix)&#160;&#160;&#160;&#160;(A) grant, extend, amend, divide, waive or modify the Company&#8217;s rights in or to any Company Intellectual Property (except as required in the diligent prosecution of the Owned Intellectual Property Rights), including any rights consisting of a license, covenant not to sue, immunity from suit, or any other similar rights and including by filing divisional or continuation patent applications or by amending claim scope in pending patent applications (B) fail to diligently prosecute any Company Intellectual Property for which the Company is responsible for prosecution or (C) fail to exercise a right of renewal or extension under or with respect to its rights in any Licensed Intellectual Property Rights&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(x)&#160;&#160;&#160;&#160;disclose any of the Company&#8217;s trade secrets outside of an appropriate confidentiality agreement&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xi)&#160;&#160;&#160;&#160;except as required by Law, existing Company Benefit Plans or existing Contracts, (A) grant any severance or termination pay to any employee, director, consultant or other individual service provider of the Company or its Subsidiaries which will become due and payable after the Closing Date&#59; (B) grant any employee, director or consultant any increase in compensation, bonuses or other benefits, (C) grant any new awards under any Company Benefit Plan, (D) amend or modify any outstanding award under any Company Benefit Plan, (E) take any action to accelerate the payment, or to fund or in any other way secure the payment, of compensation or benefits under any Company Benefit Plan, (F) hire or terminate (other than for cause) the employment of an employee whose annual base salary exceeds one hundred and fifty thousand U.S. Dollars ($150,000) (</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> that the Company shall give notice to Buyer with respect to any hire or termination of an employee whose annual base salary exceeds one hundred thousand U.S. Dollars ($100,000) but is less than one hundred and fifty thousand U.S. Dollars ($150,000))&#59; (F) engage or terminate the services of a consultant whose base compensation would exceed one hundred thousand U.S. Dollars ($100,000) in the aggregate in any twelve (12) month period)&#59; (G)&#160;adopt, enter into or materially amend any Company Benefit Plan&#59; or (H) enter into any collective bargaining agreement&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> that, notwithstanding anything to the contrary in this Agreement, the Company may at any time (1) cause any Company Option, or following consultation with Buyer, any existing phantom award, cash bonus right, or other existing equity or equity-based award of the Company or any Subsidiary to become vested, subject to continued service until immediately prior to the Effective Time, and (2) settle in cash or shares or make payments with respect to any Company Option, or following consultation with Buyer, any existing phantom award, cash bonus right, or other existing equity or equity-based award of the Company or any Subsidiary, in each case, so long as each award is generally treated in the same manner as other awards of the same type or class issued by the Company or the applicable Subsidiary&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xii)&#160;&#160;&#160;&#160;acquire by merger or consolidation with, or merge or consolidate with, or purchase all or substantially all of the assets of, any corporation, partnership, association, joint venture or other business organization or division thereof&#59;</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">66</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xiii)&#160;&#160;&#160;&#160;make any loans, advances or capital contributions to, or investments in, any other Person&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xiv)&#160;&#160;&#160;&#160;make any capital expenditures, other than any such expenditures as are not in excess of one hundred thousand U.S. Dollars ($100,000) individually or two hundred and fifty thousand U.S. Dollars ($250,000) in the aggregate&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xv)&#160;&#160;&#160;&#160;incur any debt or issue any debt securities or warrants or other rights to acquire debt securities of the Company or assume, guarantee or endorse, as an accommodation or otherwise, the obligations of any other Person for debt or capital obligations, in the case of any of the foregoing&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xvi)&#160;&#160;&#160;&#160;enter into any transactions with or enter into an extension of credit with any Related Person&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xvii)&#160;&#160;&#160;&#160;settle, agree to settle or waive any lawsuits, actions, suits, subpoenas, investigations or civil investigative demands, claims or other proceedings at law or in equity&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xviii)&#160;&#160;&#160;&#160;enter into any new line of business that is materially different from the current operations of the Company and its Subsidiaries&#59; </font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xix)&#160;&#160;&#160;&#160;(A) make or rescind any Tax election&#59; (B) file any amended Tax Return&#59; (C) enter into any Tax allocation agreement, Tax sharing agreement, Tax indemnity agreement or closing agreement relating to any Tax&#59; (D) surrender any right to claim a Tax refund&#59; (E) consent to any extension or waiver of the statute of limitations period applicable to any Tax claim or assessment&#59; or (F) except as required by the Accounting Standards, make any material change to any accounting principles, methods or practices&#59; </font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xx)&#160;&#160;&#160;&#160;revalue any of its material assets except as required by the Accounting Standards&#59; </font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xxi)&#160;&#160;&#160;&#160;enter into, modify, amend or terminate, or waive, release or assign any rights or claims under any Listed Contract, Company Benefit Plan, Contracts for labor and employment matters set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.13(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and Contracts relating to insurance policies set forth on </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 4.17</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, or any Contract that would have been considered as part of the foregoing if it had been entered into before the date hereof&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xxii)&#160;&#160;&#160;&#160;cancel any material third party debt owed to the Company, or grant any material discounts, credits or rebates to any customer or supplier of the Company, other than in the ordinary course of business&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xxiii)&#160;&#160;&#160;&#160;make any material change in the strategy with respect to the development or Regulatory Approval of any Preclinical Company Milestone Candidate&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xxiv)&#160;&#160;&#160;&#160;take any action that would cause the representations and warranties set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article IV</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> to become untrue&#59; </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">67</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xxv)&#160;&#160;&#160;&#160;renew or enter into any non-compete, exclusivity, non-solicitation or other agreement that would restrict or limit, in any material respect, the operations of the Company or any of its Subsidiaries after consummation of the Merger&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xxvi)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">sell, assign, lease, license (other than non-exclusive grants of licenses to Intellectual Property Rights in the ordinary course of business consistent with past practice, with a contract term not to exceed one (1) year), dispose of, or otherwise transfer, or create, incur, assume, or suffer to exist any Lien on, any Owned Intellectual Property Right&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xxvii)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">modify, amend, cancel, terminate, waive, release or assign any IP License or any rights, claims, obligations, or benefits, thereunder or enter into any Contract that would have been an IP License had it been entered into prior to the Effective Time&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xxviii)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> fail to maintain, or allow to lapse, dispose of or abandon, including by failure to pay the required fees in any jurisdiction, any Owned Intellectual Property Right, or disclose or grant permission to enter into the public domain any Confidential Information of the Company or its Subsidiaries&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xxix)&#160;&#160;&#160;&#160;</font><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">take any action or omit to take any action that could reasonably be expected to trigger the release of source code of any proprietary software included in the Owned Intellectual Property Rights or other products or services of the Company or its Subsidiaries to any third party&#59; or</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(xxx)&#160;&#160;&#160;&#160;enter into any agreement, or otherwise become obligated, to do any action prohibited under this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 6.1(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;During the Pre-Closing Period, prior to submission of material correspondence to any applicable Regulatory Authority regarding TNB-585 or any Pre-Clinical Company Milestone Candidate, the Company shall, sufficiently in advance for Buyer to review and comment, submit to Buyer proposed drafts of material correspondence with the FDA or other applicable Regulatory Authority for Buyer&#8217;s review and comment prior to submission. The Company shall also provide Buyer with copies of all Product Data and any material correspondence with the FDA or other applicable Regulatory Authority relating to the development of, or the process of obtaining Regulatory Approval for, TNB-585 or any Preclinical Company Milestone Candidate anywhere in the world received during the Pre-Closing Period.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;Nothing contained in this Agreement shall give Buyer, directly or indirectly, any right to control or direct the operations of the Company prior to the Closing. Prior to the Closing, each of the Company and Buyer shall exercise, consistent with the other terms and conditions of this Agreement, complete control and supervision over their respective businesses. </font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.2&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">No Solicitation</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">68</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;The Company shall immediately cease and cause to be terminated any negotiations and discussions with third parties (other than Buyer) regarding an Acquisition Proposal. During the Pre-Closing Period, the Company shall not, and shall cause each of the officers, directors, Subsidiaries, Affiliates, stockholders and employees of the Company and any investment banker, attorney or other advisor or representative retained by the Company not to, directly or indirectly, (i) solicit, initiate, seek, encourage, facilitate, support or induce the making, submission or announcement of any inquiry, expression of interest, proposal or offer that constitutes, or would reasonably be expected to lead to, an Acquisition Proposal, (ii) enter into, participate in, maintain or continue any negotiations regarding, or deliver or make available to any Person any non-public information with respect to, or take any other action regarding, any inquiry, expression of interest, proposal or offer that constitutes, or would reasonably be expected to lead to, an Acquisition Proposal, (iii) agree to, accept, approve, endorse or recommend (or publicly propose or announce any intention or desire to agree to, accept, approve, endorse or recommend) any Acquisition Proposal, (iv) enter into any letter of intent or any other Contract contemplating or otherwise relating to any Acquisition Proposal, or (v) submit any Acquisition Proposal to the vote of the Company Stockholders. The Company shall immediately cease and cause to be terminated any and all existing activities, discussions or negotiations with any Persons conducted prior to or on the date of this Agreement with respect to any Acquisition Proposal.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;The Company shall notify Buyer as promptly as practicable upon receipt (and in no event later than twenty-four (24) hours following such receipt) by it or any of its representatives of (i) any Acquisition Proposal, indication by any Person that it is considering making an Acquisition Proposal or amendment or modification to an Acquisition Proposal, (ii)&#160;any request for non-public information relating to the Company other than requests for information in the ordinary course of business and unrelated to an Acquisition Proposal or (iii)&#160;any inquiry or request for discussions or negotiations regarding or reasonably likely to lead to any Acquisition Proposal. As promptly as practicable (and in no event later than twenty-four (24) hours following receipt of an Acquisition Proposal), the Company shall (i) notify Buyer of the identity of such Person and (ii) provide a copy of such Acquisition Proposal, indication, inquiry or request (or, where no such copy is available, a description of such Acquisition Proposal, indication, inquiry or request), including any modifications thereto.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.3&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Confidentiality&#59; Access</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;Except as may be required by applicable Law or any listing agreement with any applicable national or regional securities exchange or pursuant to the terms and provisions of the Confidentiality Agreement, the Pre-Closing Holders and the Stockholder Representative hereby acknowledge, covenant and agree to hold any information that is non-public in confidence in accordance with the terms of the Confidentiality Agreement. In the event this Agreement is terminated for any reason, the parties shall promptly return or destroy such information in accordance with the Confidentiality Agreement.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;Subject to applicable Law and upon reasonable notice, the Company shall afford Buyer and its employees, attorneys, accountants, consultants and other representatives reasonable </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">69</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">access, during normal business hours during the Pre-Closing Period, to its properties, books, contracts, Tax Returns and records and appropriate individuals as Buyer may reasonably request (including employees, attorneys, accountants, consultants and other professionals), and during such period, the Company shall furnish promptly to Buyer such information concerning its Business, properties and personnel as Buyer may reasonably request, in each case including such access and information as is reasonably necessary in order to conduct an audit pertaining to billing and reimbursement procedures associated with clinical and other studies performed by or on behalf of the Company&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the Company may restrict the foregoing access to the extent that (i) any applicable Law requires the Company to restrict or prohibit access to any such properties or information to Buyer or (ii) such access would waive any attorney-client privilege, work product doctrine or other privilege applicable to such documents or information&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the Company will use best efforts to provide Buyer with such information in a form and manner that will not require the waiver of such privilege. Between the date of this Agreement and the Closing, the Company shall afford Buyer reasonable access to its employees and consultants for purposes of discussing and negotiating employment and&#47;or consulting arrangements between the Surviving Corporation or its Affiliate and such employees and consultants to be effective after the Effective Time. With respect to the furnishing by the Company of competitively sensitive information, outside antitrust counsel will be consulted prior to the exchange of such information, and such information shall only be exchanged in accordance with the safeguards and in the manner recommended by outside antitrust counsel for both parties to ensure that the exchange of such information would not violate any applicable Laws. In addition, any information obtained from the Company pursuant to the access contemplated by this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 6.3(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall be subject to the Confidentiality Agreement. Any access to any of the Company&#8217;s facilities shall be subject to the Company&#8217;s reasonable security measures and insurance requirements.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.4&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Notification of Certain Matters</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">By the Company</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The Company shall promptly, after any of the Company&#8217;s officers obtains actual knowledge of such matter, notify Buyer of any representation or warranty made by it contained in this Agreement becoming untrue or inaccurate in any material respect, or any failure of the Company in any material respect to comply with or satisfy any covenant, condition or agreement to be complied with or satisfied by it under this Agreement&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the delivery of any notice pursuant to this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 6.4(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall not limit or otherwise affect the remedies available hereunder to Buyer or the representations, warranties or covenants of the Company or the conditions to the obligations of Buyer. The Company shall promptly provide to Buyer in writing copies of all Product Data reasonably relating to the Business and the TeneoOne Business arising, occurring, received or delivered during the Pre-Closing Period. The Company shall promptly disclose any information that would reasonably be deemed to be material information with respect to each Regulated Product and Company Product arising, occurring, received or delivered during the Pre-Closing Period. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">By Buyer</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Buyer shall promptly, after any of Buyer&#8217;s officers obtain actual knowledge of such matter, notify the Company of any representation or warranty made by it contained in this Agreement becoming untrue or inaccurate in any material respect, or any failure </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">70</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">in any material respect of Buyer to comply with or satisfy in any material respect any covenant, condition or agreement to be complied with or satisfied by it under this Agreement&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the delivery of any notice pursuant to this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 6.4(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall not limit or otherwise affect the remedies available hereunder to the Company or the representations, warranties or covenants of Buyer or the conditions to the obligations of the Company.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.5&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">HSR Act and Antitrust Approvals</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. In connection with the transactions contemplated by this Agreement, the Company shall (and, to the extent required, shall cause its Affiliates, including its &#8220;ultimate parent entity&#8221; as that term is defined in the HSR Act, to) (a) comply promptly, but in no event later than fifteen (15) Business Days after the date hereof, with the notification and reporting requirements of the HSR Act and request early termination of the waiting period under the HSR Act and (b) as soon as practicable, make such other filings or start any pre-notification proceedings with any foreign Governmental Authorities as may be required under any applicable similar foreign Law. The Company shall use reasonable best efforts to respond to any Antitrust Information or Document Requests made of the Company or any of its Affiliates. </font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.6&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Consent of Company Stockholders</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Promptly following the execution and delivery of this Agreement and receipt of the Merger Consent (and in any event within two (2) Business Days after receipt of the Merger Consent), the Company shall&#58;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;prepare and mail to every Pre-Closing Holder a consent solicitation and information statement in a form satisfactory to Buyer (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Stockholder Notice</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) in accordance with applicable Law, including Sections 228 and 262 of the DGCL, the CGCL, the Company Charter and the Company Bylaws (i) notifying such Company Stockholder that (A) action has been taken by less than unanimous written consent of the Company Stockholders, (B) this Agreement was duly adopted and (C) appraisal and dissenters rights are available pursuant to Section 262 of the DGCL, the CGCL and any other applicable Law of any other applicable jurisdiction, (ii) soliciting such stockholders&#8217; execution of a Written Consent enclosed therein and (iii) enclosing a Letter of Transmittal&#59; and </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;duly take all other lawful actions to obtain the Requisite Stockholder Approval. Any materials other than the Stockholder Notice (including any amendments thereto) submitted to Company Stockholders in accordance with this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 6.6</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall be subject to Buyer&#8217;s advance review and reasonable approval. Promptly following receipt of duly executed Written Consents representing the Requisite Stockholder Approval, the Company shall cause its corporate Secretary to deliver copies of such Written Consents to Buyer, together with a certificate executed on behalf of the Company by its corporate Secretary certifying that such Written Consents reflects the Requisite Stockholder Approval. </font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.7&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Data Room Disk</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. No later than three (3) days following the date of this Agreement, the Company shall deliver to Buyer a disk containing copies of all documents then contained in the &#8220;TNB-585 Amgen Due Diligence&#8221; virtual data room at comhttps&#58;&#47;&#47;teneobio.sharepoint.commaintained by the Company in connection with the transactions contemplated by this Agreement, which virtual data room shall contain all documents included in such virtual data room as of 11&#58;59 p.m. (Eastern Time) on the date that is one (1) day prior to the </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">71</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">date of this Agreement, and the phrase &#8220;made available to Buyer&#8221; or similar phrases as used in the Agreement shall mean the subject documents were posted to such data room.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 6.8&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Restructuring</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;Prior to the Closing, the Company shall use its best efforts to (i) prepare, execute and deliver all agreements, instruments, certificates and other documents, (ii) make all filings, disclosures, applications and notifications, and (iii) perform all such actions as may be required or advisable in connection with the consummation of the transactions pursuant to the Restructuring Step Plan&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> that any such documents, filings, disclosures, applications, notices and other materials so prepared shall be subject to Buyer&#8217;s review and approval prior to execution or submission (such approval not to be unreasonably withheld).  </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;Prior to the Closing, the Company shall provide evidence in form and substance satisfactory to Buyer that (i) the Company owns one hundred percent (100%) of the Equity Interests in each of TeneoThree, TeneoFive, TeneoSix, TeneoSeven, TeneoEight, and TeneoNine (collectively, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Acquired Subsidiaries</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) free and clear of all Liens pursuant to the Restructuring Step Plan, (ii) the Company has distributed or sold, as applicable, all Equity Interests in the Excluded Entities held by the Company pursuant to the Restructuring Step Plan, and (iii) the other transactions described in the Restructuring Step Plan, including the consummation of the TeneoOne Sale, have been completed as provided therein (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Restructuring</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). At the Closing, the Company shall directly hold one hundred percent (100%) of the Equity Interests in each of the Acquired Subsidiaries and the Pre-Closing Holders shall hold one hundred percent (100%) of the Equity Interests of the Company.</font></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">ARTICLE VII.<br>COVENANTS OF BUYER</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 7.1&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">HSR Act and Antitrust Approvals</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. In connection with the transactions contemplated by this Agreement, Buyer shall (i) comply promptly, but in no event later than fifteen (15) Business Days after the date hereof, with the notification and reporting requirements of the HSR Act and use its reasonable best efforts to obtain early termination of the waiting period under the HSR Act and (ii) as soon as practicable, make such other filings or start pre-notification proceedings with any foreign Governmental Authorities as may be required under any applicable similar foreign Law. Buyer shall use its reasonable best efforts to respond to any Antitrust Information or Document Requests made of Buyer or any of its Affiliates.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 7.2&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Director &#38; Officer Indemnification and Insurance</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;Prior to the Closing, the Company shall obtain, at its expense, a fully prepaid directors&#8217; and officers&#8217; liability insurance policy approved by Buyer (such approval not to be unreasonably withheld, conditioned or delayed), which (i) has an effective term of up to six (6) years from the Effective Time and (ii) covers the Company&#8217;s directors and officers for matters occurring at or prior to the Effective Time (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company D&#38;O Policy</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). Buyer shall cause the Company D&#38;O Policy to be maintained in full force and effect for the term of such policy.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">72</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;Buyer shall cause the Company for a period of not less than six (6) years from the Effective Time to provide indemnification of the Company&#8217;s former and current officers and directors that are no less favorable to those Persons than the provisions of the indemnification agreements with the Company and the certificate of incorporation and bylaws of the Company, in each case, as of the date of this Agreement. </font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 7.3&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Employment Matters</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;For a period of not less than twelve (12) months after the Closing Date, Buyer and its Affiliates shall provide, or shall cause the Surviving Corporation to provide, to each employee of the Company and its Subsidiaries who continues in employment with Buyer and its Affiliates (including the Surviving Corporation) immediately following the Closing (each, a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Continuing Employee</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), (i) a base salary or regular hourly wage, as applicable, that is not less than the base salary or regular hourly wage, as applicable, provided to such Continuing Employee immediately prior to the execution of this Agreement, (ii) annual cash-based bonus targets that are no less favorable than the cash-based bonus targets provided to such Continuing Employee immediately prior to the execution of this Agreement, and (iii)&#160;employee and fringe benefits (including, health, welfare, retirement and severance benefits but excluding equity and long-term incentive compensation) that are, in the aggregate and at a minimum, substantially equivalent to the benefits provided to such Continuing Employee immediately prior to the execution of this Agreement.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;Effective as of the Closing and thereafter, Buyer and its Affiliates shall recognize, or shall cause the Surviving Corporation to recognize, each Continuing Employee&#8217;s employment or service with the Company (including any current or former Affiliate of the Company or any predecessor of the Company) prior to the Closing for all purposes, including for purposes of determining, as applicable, eligibility for participation, vesting and entitlement of the Continuing Employee under all employee benefit plans maintained by the Surviving Corporation, Buyer or an Affiliate of Buyer, including vacation plans or arrangements, retirement plans and any severance or welfare plans (but excluding equity-based compensation plans), except to the extent such recognition would result in a duplication of benefits and other than for benefit accrual purposes under any defined benefit pension plan. In addition, and without limiting the generality of the foregoing, Buyer and its Affiliates shall use commercially reasonable efforts, or shall cause the Surviving Corporation to use commercially reasonable efforts, to the extent not prohibited by the terms, or by any third party administrator, of any fully insured medical, dental, pharmaceutical or vision benefit plan of the Surviving Corporation, Buyer or an Affiliate of Buyer (i) to cause any pre-existing conditions or limitations, eligibility waiting periods, actively at work requirements, evidence of insurability requirements or required physical examinations under any health or similar plan of the Surviving Corporation, Buyer or an Affiliate of Buyer to be waived with respect to Continuing Employees and their eligible dependents, except to the extent that any waiting period, exclusions or requirements still applied to such Continuing Employee under the comparable Company Benefit Plan in which such Continuing Employee participated immediately before the Closing, and to (ii) credit each Continuing Employee with all deductible payments, co-payments and other out-of-pocket expenses incurred by such Continuing Employee and his or her covered dependents under the medical, dental, </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">73</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">pharmaceutical or vision benefit plans of the Company prior to the Closing during the plan year in which the Closing occurs for the purpose of determining the extent to which such Continuing Employee has satisfied the deductible, co-payments, or maximum out-of-pocket requirements applicable to such Continuing Employee and his or her covered dependents for such plan year under any medical, dental, pharmaceutical or vision benefit plan of the Surviving Corporation, Buyer or an Affiliate of Buyer, as if such amounts had been paid in accordance with such plan (to the extent such credit would have been given under comparable Company Benefit Plans prior to the Closing). </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;Effective no later than the day immediately prior to the Closing Date, the Company shall take or cause to be taken all actions necessary to terminate any and all Company Benefit Plans intended to qualify as qualified cash or deferred arrangements under Section&#160;401(k) of the Code (each, a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company 401(k) Plan</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). The Company shall provide Buyer with evidence that such Plan has been terminated (the form and substance of which shall be subject to review and approval by Buyer) no later than the day immediately prior to the Closing Date. For the avoidance of doubt, in connection with the termination of such Company Benefit Plans, all Company matching contributions will fully vest. Prior to the Closing Date and thereafter (as applicable), the Company and Buyer shall use commercially reasonable efforts to permit each Continuing Employee to make rollover contributions of &#8220;eligible rollover distributions&#8221; (within the meaning of Section 401(a)(31) of the Code), excluding rollovers of outstanding plan loans, in an amount equal to the full account balance distributed or distributable to such Continuing Employee from the Company 401(k) Plan to Buyer&#8217;s benefit plan intended to qualify as qualified cash or deferred arrangements under Section&#160;401(k) of the Code. With respect to each Company Benefit Plan sponsored or maintained by a professional employer organization, the Company shall take all necessary action to (i) cause the active participation by the Company and its employees in such plan to terminate and cease effective prior to the Closing, and (ii) terminate the service agreement with such professional employer organization effective prior to the Closing.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;If any Person who is a &#8220;disqualified individual&#8221; (within the meaning of Section&#160;280G of the Code and the Department of Treasury regulations promulgated thereunder) with respect to the Company or its Subsidiaries (including any Excluded Entity) may receive any payment(s) or benefit(s) that would reasonably be expected to constitute parachute payments under Section 280G of the Code in connection with the transactions contemplated by this Agreement, then&#58; (a) the Company shall undertake commercially reasonable efforts to obtain and deliver to Buyer a Parachute Payment Waiver from each such &#8220;disqualified individual&#8221;&#59;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:7.8pt;font-weight:400;line-height:120%;position:relative;top:-4.2pt;vertical-align:baseline"> </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">and (b) as soon as practicable following the delivery of the Parachute Payment Waivers (if any) to Buyer, the Company shall prepare and distribute to its shareholders a disclosure statement describing all potential parachute payments and benefits that may be received by such disqualified individual(s) who executed a Parachute Payment Waiver and shall submit such payments to its shareholders for approval, in each case, in accordance with the requirements of Section 280G(b)(5)(B) of the Code and the Department of Treasury regulations promulgated thereunder, such that, if approved by the requisite majority of the shareholders, such payments and benefits shall not be deemed to be &#8220;parachute payments&#8221; under Section 280G of the Code (the foregoing actions, a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">280G Vote</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). Prior to the Closing, if a 280G Vote is required to be </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">74</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">undertaken pursuant to the foregoing subclause (b), the Company shall deliver to Buyer evidence reasonably satisfactory to Buyer, (i) that a 280G Vote was solicited in conformance with Section&#160;280G of the Code, and the requisite shareholder approval was obtained with respect to any payments and&#47;or benefits that were subject to the Company shareholder vote (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section&#160;280G Approval</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) or (ii) that the Section 280G Approval was not obtained and as a consequence, pursuant to the Parachute Payment Waiver, such &#8220;parachute payments&#8221; shall not be made or provided. The form of the Parachute Payment Waiver, the disclosure statement, any other materials to be submitted to the Company&#8217;s shareholders in connection with the Section&#160;280G Approval and the calculations related to the foregoing shall be subject to advance review by Buyer, and the Company shall consider in good faith any comments provided by Buyer. Prior to the Company soliciting the approval described in this paragraph, Buyer shall notify the Company of any payments Buyer or any of its Affiliates intends to make to any such disqualified individuals, if such payments would reasonably be considered parachute payments under Section 280G of the Code (such payments, &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Buyer Parachute Payments</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;)&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> that, if Buyer does not timely notify the Company of such Buyer Parachute Payments, this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 7.3(d)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall not apply to such Buyer Parachute Payments.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;Nothing contained in this Agreement shall, or shall be construed so as to, (i)&#160;prevent or restrict in any way the right of the Buyer or its Affiliates (including the Surviving Corporation) to terminate, reassign, promote or demote any employee, independent contractor, director or other service provider of the Company or its Subsidiaries (or to cause any of the foregoing actions) at any time following the Closing, or to change (or cause the change of) the title, powers, duties, responsibilities, functions, locations, salaries, other compensation or terms or conditions of employment or service of any such service providers at any time following the Closing&#59; (ii) constitute an amendment or modification of any Company Benefits Plan or employee benefit plan&#59; or (iii) create any third party rights in any such current or former service provider of the Company or its Subsidiaries (including any beneficiary or dependent thereof)&#59; or (iv) obligate the Buyer to adopt or maintain any particular plan or program or other compensatory or benefits arrangement at any time or prevent the Buyer from modifying or terminating any such plan, program or other compensatory or benefits arrangement at any time.</font></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">ARTICLE VIII.<br>JOINT COVENANTS</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 8.1&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Support of Transaction</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Without limiting any covenant contained in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article&#160;VI</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article&#160;VII</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, Buyer and the Company shall each, and Buyer shall cause its Subsidiaries to&#58; (a) use reasonable best efforts to assemble, prepare and file any information (and, as needed, to supplement such information) as may be reasonably necessary to obtain as promptly as practicable all governmental and regulatory consents required to be obtained in connection with the transactions contemplated hereby (other than approvals under the HSR act or any other approvals, consents and decrees under antitrust or competition law, which matters are exclusively addressed in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Sections 6.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">7.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">8.6</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">)&#59; (b)&#160;use reasonable best efforts to obtain all material consents and approvals of third parties that any of Buyer, the Company or their respective Affiliates are required to obtain in order to consummate the Merger, including the Required Third Party Consents&#59; and (c) take such other action as may reasonably be necessary or </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">75</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">as another party may reasonably request to satisfy the conditions of </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article IX</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or otherwise to comply with this Agreement and to consummate the transactions contemplated hereby as soon as practicable (but in any event prior to the Outside Date). Notwithstanding the foregoing, in no event shall Buyer or its Affiliates be obligated to bear any expense or pay any fee (other than the payment of nominal administrative, processing or similar fees or charges or legal fees to its attorneys) or grant any concession in connection with obtaining any consents, authorizations or approvals required in order to consummate the Merger pursuant to the terms of any Contract to which the Company is a party.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 8.2&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Escrow Agreement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Each of the Company, the Stockholder Representative and Buyer shall execute and deliver to one another, at the Closing, the Escrow Agreement in the form attached hereto as </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Exhibit F</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Escrow Agreement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;).</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 8.3&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Stockholder Approval</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Within two (2) Business Days after the execution and delivery of this Agreement, the Company shall, in accordance with the DGCL and the CGCL, the Company Charter and the Company Bylaws, obtain and deliver to Buyer the Merger Consent.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 8.4&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Further Assurances</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Each party hereto agrees that, from time to time after the Closing Date, it will execute and deliver, or cause its Affiliates to execute and deliver, such further instruments, and take (or cause its Affiliates to take) such other action, as may be reasonably necessary to carry out the purposes and intents of this Agreement.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 8.5&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Tax Matters</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;The Stockholder Representative shall prepare and timely file, or shall cause to be prepared and timely filed, all Tax Returns in respect of the Company or any of its Subsidiaries that relate to taxable periods ending on or before the Closing that are required to be filed after the Closing, and the Pre-Closing Holders shall pay, or cause to be paid, all Taxes due with respect to such Tax Returns to the extent such Taxes were not reflected in Closing Date Funded Debt (as finally determined in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">). At least twenty (20) days prior to filing any such Tax Return, the Stockholder Representative shall submit a copy of such Tax Return to the Buyer for the Buyer&#8217;s review and comment and shall incorporate all reasonable comments provided by Buyer no less than five (5) Business Days prior to the due date of such Tax Returns. The Pre-Closing Holders shall make the payment due to the Company under this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.5(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> at least two (2) Business Days before payment of Taxes (including for the avoidance of doubt estimated Taxes) is due to the applicable Tax Authority.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;The Company shall prepare and timely file, or cause to be prepared and timely filed, any Tax Return (a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Straddle Period Tax Return</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) required to be filed by the Company or any of its Subsidiaries for any Straddle Period, and the Pre-Closing Holders shall pay, or cause to be paid, all Taxes due with respect to such Tax Returns to the extent such Taxes are both (i)&#160;allocable to the Pre-Closing Tax Period and (ii) not reflected in Closing Date Funded Debt (as finally determined in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">). The Company shall deliver at least ten (10) days prior to the due date (taking into account any extension) for the filing of such Straddle Period Tax Returns to the Stockholder Representative for the Stockholder Representative&#8217;s </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">76</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">review a draft of all such Straddle Period Tax Returns. The Company shall consider in good faith any reasonable comment that the Stockholder Representative submits to the Company no less than five (5) Business Days prior to the due date of such Straddle Period Tax Returns. The Pre-Closing Holders shall make the payment due to the Company under this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.5(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> at least two (2) Business Days before payment of Taxes (including, for the avoidance of doubt, estimated Taxes) is due to the applicable Tax Authority.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;For purposes of this Agreement, with respect to a Straddle Period, (x) in the case of any Property Taxes, the amount of such Property Taxes that relates to the Pre-Closing Tax Period shall be equal to the amount of such Property Taxes for the entire Straddle Period multiplied by a fraction, the numerator of which is the number of calendar days during the Straddle Period that are in the Pre-Closing Tax Period and the denominator of which is the total number of calendar days in the Straddle Period, and (y) in the case of any Taxes other than Property Taxes, the amount of such Taxes that relates to the Pre-Closing Tax Period shall be determined as though the taxable year of the Company and its Subsidiaries terminated at the close of business on the Closing Date.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;Buyer and the Company and its Subsidiaries, on the one hand, and the Stockholder Representative, the Pre-Closing Holders and their respective Affiliates, on the other hand, shall promptly notify each other upon receipt by such party of written notice of any inquiries, claims, assessments, audits or similar events with respect to Taxes or Tax Returns of the Company and its Subsidiaries relating to a Pre-Closing Tax Period (any such inquiry, claim, assessment, audit or similar event, a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Tax Contest</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). Any failure to so notify the other party of any Tax Contest shall not relieve such other party of any liability with respect to such Tax Contest except to the extent such party was actually prejudiced as a result thereof. The Stockholder Representative may elect to control the conduct of any Tax Contest that relates solely to taxable periods ending on or before the Closing Date and is not expected to have a material adverse effect on Buyer or the Company with respect to taxable periods (or portions thereof) beginning after the Closing Date (a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Seller Tax Contest</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), including any settlement or compromise thereof&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the Stockholder Representative shall keep Buyer reasonably informed of the progress of any Seller Tax Contest, and Buyer shall be entitled to participate in any Seller Tax Contest. The Stockholder Representative shall not settle or compromise any Seller Tax Contest without obtaining Buyer&#8217;s prior written consent, which shall not be unreasonably withheld or delayed. Buyer shall have sole control of the conduct of all other Tax Contests, including any settlement or compromise thereof&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that Buyer shall keep the Stockholder Representative reasonably informed of the progress of any such Tax Contest, and the Stockholder Representative shall be entitled to participate in any such Tax Contest at the Pre-Closing Holders&#8217; sole cost and expense. Buyer shall not settle or compromise any such Tax Contest with respect to which Pre-Closing Holders are liable pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article XI</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> without obtaining the Stockholder Representative&#8217;s prior written consent, which consent shall not be unreasonably withheld, conditioned or delayed. &#91;***&#93;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;The Pre-Closing Holders shall cooperate fully, as and to the extent reasonably requested by Buyer, in connection with the filing of any Tax Returns of the Company and its Subsidiaries and in any audit, litigation or other proceeding with respect to Taxes. Buyer and the </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">77</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Pre-Closing Holders agree to furnish or cause to be furnished to the other, upon request, as promptly as practicable, such information and assistance relating to Taxes, including access to books and records, as is reasonably necessary for the filing of all Tax Returns by Buyer or the Pre-Closing Holders, the making of any election relating to Taxes, the preparation for any audit by any Tax Authority and the prosecution or defense of any claim, suit or proceeding relating to any Tax. Each of Buyer and the Pre-Closing Holders shall retain all books and records with respect to Taxes for a period of at least seven (7) years following the Closing.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(f)&#160;&#160;&#160;&#160;All Transfer Taxes, if any, arising out of or in connection with the transactions contemplated by this Agreement shall be paid one-half (1&#47;2) by the Pre-Closing Holders and one-half (1&#47;2) by Buyer when due. The Pre-Closing Holders further agree, upon request, to use commercially reasonable efforts to obtain any certificate or other document from any Tax Authority or any other Person as may be necessary to mitigate, reduce or eliminate any Transfer Taxes that could be imposed in connection with the transactions contemplated hereby.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(g)&#160;&#160;&#160;&#160;In the case of any conflict, overlap or inconsistency between this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article XI</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall control as to Tax matters.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 8.6&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">HSR Act and Antitrust Approvals</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;Each of Buyer and the Company shall exercise its reasonable best efforts and take all necessary steps to (i) obtain termination or expiration of the waiting period under the HSR Act and such other approvals, consents and clearances as may be necessary, proper or advisable under any foreign antitrust or competition laws (collectively, &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Antitrust Laws</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), in each case, as soon as practicable (but in any event prior to the Outside Date), (ii)&#160;furnish to the other party all information required for any application or other filing to be made pursuant to any Law in connection with the transactions contemplated by this Agreement, and (iii) otherwise cooperate with the other parties hereto in connection with any filing and in connection with resolving any investigation or other inquiry of any Governmental Authority. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;Notwithstanding anything to the contrary set forth in this Agreement, including the provisions contained in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article VI</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article VII</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, none of Buyer, Merger Sub, the Company or their respective Affiliates shall be required to, and the Company and its Affiliates may not, without the prior written consent of Buyer, become subject to, consent to, or offer or agree to, or otherwise take any action with respect to, any requirement, condition, limitation, understanding, agreement or Governmental Order to&#58; (i)&#160;pay any sums or concede anything of value (other than filing fees under the HSR Act and other Antitrust Laws and reasonable professional advisors&#8217; fees in connection therewith)&#59; (ii)&#160;sell, license, assign, transfer, divest, hold separate or otherwise dispose of, or agree to sell, license, assign, transfer, divest, hold separate or otherwise dispose of, any assets, business or portion of the business of the Company, Buyer or their respective Affiliates or otherwise commit to take any action that would reasonably be expected to limit Buyer&#8217;s, Merger Sub&#8217;s, the Company&#8217;s or any of their respective Affiliates&#8217; action with respect to, or their ability to retain, one or more businesses, product lines or assets&#59; (iii)&#160;conduct, restrict, operate, invest or otherwise change the assets, business or any portion of business of Buyer, the Company or any of their respective Affiliates in any manner&#59; (iv)&#160;impose any restriction, requirement or limitation on the operation of the business or any portion of the business of </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">78</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Buyer, the Company or any of their respective Affiliates&#59; (v) terminate, modify or extend any existing relationships and contractual rights and obligations of Buyer, the Company or any of their respective Affiliates&#59; (vi)&#160;establish or create any relationships and contractual rights and obligations of Buyer, the Company or any of their respective Affiliates&#59; (vii)&#160;terminate any relevant venture or other arrangement&#59; (viii)&#160;effectuate any other change or restructuring of Buyer, the Company or their respective Affiliates (and, in each case, to enter into agreements or stipulate to the entry of an Order or file appropriate applications with the Federal Trade Commission, the Antitrust Division of the Department of Justice or other Governmental Authority)&#59; or (ix)&#160;litigate (or defend) against any administrative or judicial Action (including any proceeding seeking a temporary restraining order or preliminary injunction) challenging any of the transactions contemplated by this Agreement as violative of any applicable Law&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> that, if requested by Buyer (in its sole and absolute discretion), the Company shall, and shall cause any of its controlled Affiliates to, become subject to, consent to, or offer or agree to, or otherwise take any action with respect to, any such requirement, condition, limitation, understanding, agreement or Governmental Order so long as such requirement, condition, limitation, understanding, agreement or Governmental Order is only binding on the Company or any of its controlled Affiliate after the Closing (in the event the Closing occurs). In addition, Buyer and its Affiliates shall be permitted to acquire any Equity Interest in, acquire any, all or substantially all of the assets of, merge, consolidate, enter into a share exchange or business combination with, or enter into any other similar transaction or series of transactions with, any Person and the parties agree that no such transaction shall be a breach of </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.6</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;Each of Buyer and the Company shall promptly furnish to the other party copies of any notices or written communications received or given by such party or any of its Affiliates from or to any third party or any Governmental Authority with respect to the transactions contemplated by this Agreement, and such party shall permit counsel to the other party an opportunity to review in advance, to the extent reasonably practicable, and shall consider in good faith the views of such counsel in connection with, any proposed written communications by such party and its Affiliates to any third party or any Governmental Authority concerning the transactions contemplated by this Agreement. Each of Buyer and the Company agrees to provide the other party and its counsel the opportunity, on reasonable advance notice, to participate in any substantive meetings or discussions, either in person or by telephone, between such party and any of its Affiliates, agents or advisors, on the one hand, and any third party or any Governmental Authority, on the other hand, concerning or in connection with the transactions contemplated hereby&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> that Buyer shall lead all communications and strategy for dealing with the FTC, the DOJ and any other Governmental Authority in connection with any review pursuant to the HSR Act or any other applicable Antitrust Laws. Without limiting the generality of the foregoing, each of Buyer and the Company shall provide to the other (or the other&#8217;s respective advisors) upon request copies of all correspondence between such party and any Governmental Authority relating to the transactions contemplated by this Agreement. Notwithstanding anything to the contrary in this Agreement, Buyer and the Company, as applicable, may, as such party deems advisable and necessary, (1) redact materials provided to the other under this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.6(c)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> to (A)&#160;remove references concerning the valuation of Buyer, Merger Sub, the Company, or any of their respective Subsidiaries or assets, (B) as necessary to </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">79</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">comply with contractual arrangements, and (C) as necessary to address reasonable privilege concerns, and (2) designate any competitively sensitive materials provided to the other under this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.6(c)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> as &#8216;outside counsel only,&#8217; which materials and the information contained therein shall be given only to outside counsel of the recipient and will not be disclosed by such outside counsel to employees, officers, or directors of the recipient without the advance written consent of the party providing such materials. In addition, to the extent reasonably practicable, all discussions, telephone calls, and meetings with a Governmental Authority regarding the transactions contemplated by this Agreement shall include representatives of both Buyer and the Company. Subject to applicable Law, each of Buyer and the Company will consult and cooperate with each other in connection with any analyses, appearances, presentations, memoranda, briefs, arguments, and proposals made or submitted to any Governmental Authority regarding the transactions contemplated by this Agreement by such party or on its behalf.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;Buyer shall be responsible for the payment of, and shall pay or cause to be paid on its behalf, all filing fees under the HSR Act and other similar Antitrust Laws (whether domestic or foreign), to the extent applicable.</font></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">ARTICLE IX.<br>CONDITIONS TO OBLIGATIONS</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 9.1&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Conditions to the Obligations of Buyer, Merger Sub and the Company</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The obligations of Buyer, Merger Sub and the Company to consummate, or cause to be consummated, the Merger are subject to the satisfaction of the following conditions, any one or more of which may be waived in writing by all of such parties&#58;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;All waiting periods under the HSR Act applicable to the Merger shall have expired or been terminated and all consents or approvals applicable to or advisable in connection with the Merger under any foreign antitrust law shall have been obtained.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;No Governmental Authority of competent jurisdiction shall have enacted, issued, promulgated, enforced or entered any statute, rule, regulation, executive order, decree, injunction or other order (whether temporary, preliminary or permanent) which is in effect and which prohibits, restrains, enjoins or makes illegal the consummation of the Merger, and there shall not be any threatened, instituted or pending action by a Governmental Authority seeking to prohibit, restrain or enjoin the consummation of the Merger or other transactions under this Agreement.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;The Merger Consent shall have been validly obtained and be in full force and effect.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 9.2&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Conditions to the Obligations of Buyer and Merger Sub</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">The obligations of Buyer and Merger Sub to consummate, or cause to be consummated, the Merger are subject to the satisfaction of the following additional conditions, any one or more of which may be waived in writing by Buyer and Merger Sub&#58;</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">80</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;Each of the representations and warranties of the Company contained in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article&#160;IV</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, disregarding all qualifications contained herein relating to materiality or Material Adverse Effect, shall be true and correct in all respects as of the date hereof and as of the Closing Date, as if made anew at and as of that date, except with respect to representations and warranties which speak as to an earlier date, which representations and warranties shall be true and correct at and as of such date, except for (i) any inaccuracy or omission that would not reasonably be expected to have a Material Adverse Effect, (ii) notwithstanding </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 9.2(a)(i)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, (A) the Fundamental Representations, shall be true and correct in all respects except for such inaccuracies which are </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-style:italic;font-weight:400;line-height:120%">de minimis</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, individually or in the aggregate and (B) the representations and warranties contained in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.11</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.20</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall be true and correct in all material respects.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;Each of the covenants of the Company to be performed at or prior to the Closing shall have been performed in all material respects.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;The Company shall have delivered to Buyer a certificate signed by an officer of the Company, dated as of the Closing Date, certifying that, to the knowledge and belief of such officer, the conditions specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 9.2(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 9.2(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> have been fulfilled.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;The Company shall have delivered to Buyer a certificate in accordance with the requirements of Treasury Regulation Sections 1.897-2(h) and 1.1445-2(c)(3) dated within thirty (30) days prior to the Closing Date certifying that the Company is not a &#8220;United States real property holding corporation&#8221; within the meaning of Section 897(c)(2) of the Code along with written authorization for Buyer to deliver such notice form to the IRS on behalf of the Company upon Closing.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;There shall not have occurred since the Company Balance Sheet Date any Material Adverse Effect nor shall events have occurred that, individually or in the aggregate, would reasonably be expected to result in a Material Adverse Effect.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(f)&#160;&#160;&#160;&#160;The Required Third Party Consents shall have been obtained in form and substance reasonably satisfactory to Buyer.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(g)&#160;&#160;&#160;&#160;The Restructuring shall have been completed pursuant to the Restructuring Step Plan.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(h)&#160;&#160;&#160;&#160;The Company shall have delivered to Buyer the Second Amended and Restated License Agreements executed by each of TeneoTwo, TeneoFour and TeneoTen and such Second Amended and Restated License Agreements shall not have been terminated and shall be in full force and effect.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(i)&#160;&#160;&#160;&#160;No less than three (3) days prior to the Closing Date, the Company will have obtained and delivered to Buyer true, correct and complete copies of Written Consents executed by Company Stockholders representing (a) ninety percent (90%) of the votes represented by all outstanding shares of Company Capital Stock voting together as a single class on an as-converted basis and (b) each Pre-Closing Holder who owns in excess of five percent (5%) of the </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">81</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">outstanding Company Capital Stock on a fully diluted basis (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Requisite Stockholder Approval</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) and such Requisite Stockholder Approval shall have been validly obtained and be in full force and effect at the Closing.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(j)&#160;&#160;&#160;&#160;Evidence satisfactory to Buyer that each Company Benefit Plan intended to be qualified under Section 401(k) of the Code has been terminated effective as of the day immediately prior to the Closing pursuant to resolutions duly adopted by the board of directors of the Company sponsoring such Company Benefit Plan(s).</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(k)&#160;&#160;&#160;&#160;If a 280G Vote is required to be undertaken under </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 7.3(d)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> hereof, (i) the Company shall have solicited from each Person who is eligible to receive a payment that may constitute a &#8220;parachute payment&#8221; under Section 280G of the Code prior to soliciting the Section 280G Approval and, to the extent received by the Company, delivered to Buyer each signed Parachute Payment Waiver and (ii) to the extent any Parachute Payment Waivers are executed, the Company&#8217;s shareholders shall have (A)&#160;approved, pursuant to the method provided for in the regulations promulgated under Section&#160;280G of the Code, any such &#8220;parachute payments&#8221; or (B) shall have voted upon and disapproved such &#8220;parachute payments,&#8221; and, as a consequence, such &#8220;parachute payments&#8221; shall not be paid or provided for in any manner and Buyer and its Affiliates shall not have any Liabilities with respect to such &#8220;parachute payments.&#8221;</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 9.3&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Conditions to the Obligations of the Company</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The obligations of the Company to consummate, or cause to be consummated, the Merger are subject to the satisfaction of the following additional conditions, any one or more of which may be waived in writing by the Company&#58;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;Each of the representations and warranties of Buyer and Merger Sub contained in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article V</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, disregarding all qualifications contained herein relating to materiality or Material Adverse Effect, shall be true and correct in all material respects as of the Closing Date, as if made anew at and as of that date, except with respect to representations and warranties which speak as to an earlier date, which representations and warranties shall be true and correct at and as of such date, except for (i) any inaccuracy or omission that would not reasonably be expected to have a material adverse effect on Buyer&#8217;s ability to consummate the Merger, and (ii) the representations and warranties set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 5.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 5.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 5.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 5.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall be true and correct in all respects except for such inaccuracies which are </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-style:italic;font-weight:400;line-height:120%">de minimis</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, individually or in the aggregate.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;Each of the covenants of Buyer and Merger Sub to be performed at or prior to the Closing shall have been performed in all material respects.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;Buyer shall have delivered to the Company a certificate signed by an officer of Buyer, dated as of the Closing Date, certifying that, to the knowledge and belief of such officer, the conditions specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 9.3(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 9.3(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> have been fulfilled.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 9.4&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Waiver of Conditions&#59; Frustration of Conditions</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. All conditions to the Closing shall be deemed to have been satisfied or waived following the Effective Time. None of the Company, Buyer or Merger Sub may rely on the failure of any condition set forth in this </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">82</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article&#160;IX</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> to be satisfied if such failure was caused by the failure of the Company, on the one hand, or Buyer or Merger Sub, on the other hand, respectively, to comply with its obligations under this Agreement.</font></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">ARTICLE X.<br>TERMINATION</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 10.1&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Termination</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. This Agreement may be terminated and the transactions contemplated hereby abandoned at any time prior to the Closing&#58;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;by duly authorized mutual written consent of Buyer and the Company&#59;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;by written notice to the Company from Buyer if&#58;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(i)&#160;&#160;&#160;&#160;there is any material breach of any representation, warranty, covenant or agreement on the part of the Company set forth in this Agreement, such that the conditions specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 9.2(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 9.2(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> would not be satisfied at the Closing, except that, if such breach is curable by the Company through the exercise of its reasonable best efforts, then, for a period of up to thirty (30) days after receipt by the Company of notice from Buyer of such breach, but only as long as the Company continues to use its reasonable best efforts to cure such breach (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Company Cure Period</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), such termination not to be effective until the end on the Company Cure Period, and such termination shall become effective only if such breach is not cured within the Company Cure Period&#59; </font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(ii)&#160;&#160;&#160;&#160;the Closing has not occurred on or before October 25, 2021 (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Outside Date</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), unless Buyer&#8217;s or Merger Sub&#8217;s breach is the primary reason for the Closing not occurring on or before such date&#59; </font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(iii)&#160;&#160;&#160;&#160;the consummation of any of the transactions contemplated hereby is permanently enjoined, prohibited or otherwise restrained by the terms of a final, non-appealable order or judgment of a court of competent jurisdiction&#59; or</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(iv)&#160;&#160;&#160;&#160;if the Merger Consent has not been delivered within one (1) Business Day following the execution and delivery of this Agreement&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the right to terminate this Agreement pursuant to this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 10.1(b)(iv)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall terminate upon delivery of the Merger Consent&#59;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;by written notice to Buyer from the Company if&#58;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(i)&#160;&#160;&#160;&#160;there is any material breach of any representation, warranty, covenant or agreement on the part of Buyer or Merger Sub set forth in this Agreement, such that the conditions specified in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 9.3(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 9.3(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> would not be satisfied at the Closing, except that, if any such breach is curable by Buyer through the exercise of its reasonable best efforts, then, for a period of up to thirty (30) days after receipt by Buyer of notice from the Company of such breach, but only as long as Buyer continues to </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">83</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">exercise such reasonable best efforts to cure such breach (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Buyer Cure Period</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), such termination not to be effective until the end on the Buyer Cure Period, and such termination shall become effective only if such breach is not cured within the Buyer Cure Period&#59;</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(ii)&#160;&#160;&#160;&#160;the Closing has not occurred on or before the Outside Date, unless the Company&#8217;s breach is the primary reason for the Closing not occurring on or before such date&#59; or</font></div><div style="margin-bottom:12pt;padding-left:36pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(iii)&#160;&#160;&#160;&#160;the consummation of any of the transactions contemplated hereby is permanently enjoined, prohibited or otherwise restrained by the terms of a final, non-appealable order or judgment of a court of competent jurisdiction.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 10.2&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Effect of Termination</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Except as otherwise set forth in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 10.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, in the event of the termination of this Agreement pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 10.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, this Agreement shall forthwith become void and have no effect, without any liability on the part of any party hereto or its respective Affiliates, officers, directors, employees or stockholders, other than liability of the Company, Buyer or Merger Sub, as the case may be, for any fraud or willful breach of this Agreement occurring prior to such termination, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> that the provisions of this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article&#160;X</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article XIII</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, and the definitions used therein, shall survive the termination of this Agreement.</font></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">ARTICLE XI.<br>INDEMNIFICATION</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.1&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Survival of Representations and Warranties</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The representations and warranties of Buyer, Merger Sub and the Company contained herein shall survive the Closing and the Buyer Indemnified Parties shall be entitled to seek indemnification pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.2(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section&#160;11.3(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, as applicable, (i) with respect to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 4.15</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (Taxes), until the thirtieth (30th) day following the expiration of the applicable statute of limitations (including any extensions thereto) (ii) with respect to all other Fundamental Representations, until the date that is seven (7) years following the Closing, (iii) with respect to the Semi-Fundamental Representations, until the date that is three (3) years following the Closing, and (iv) with respect to all other representations and warranties of Buyer, Merger Sub and the Company herein, until the date that is fifteen (15) months following the Closing. Each Indemnified Party must give written notice to the respective Indemnifying Party of any claim for indemnification under this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article XI</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Any claim for indemnification made in writing by the Indemnified Party on or prior to the expiration of the applicable survival period shall survive until such claim is finally and fully resolved. All of the covenants and other agreements of Buyer, Merger Sub and the Company contained in this Agreement shall survive until fully performed or fulfilled.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.2&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Indemnification of Buyer</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. From and after the Closing, Buyer and its Affiliates (including, from and after the Closing, the Surviving Corporation) and each of their respective officers, directors, employees, agents and each Person, if any, who controls or may control Buyer within the meaning of the Securities Act of 1933, as amended, (each, a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Buyer Indemnified Party</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) shall be indemnified, held harmless and reimbursed by the Pre-Closing Holders, on a </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">84</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">several and not joint basis in accordance with their Pro Rata Percentage (except with respect to fraud of which such Pre-Closing Holder had actual knowledge, in which case such Pro Rata Percentage limitation shall not apply), against any and all Losses, whether or not involving a Third Party Claim, arising out of, related to, or resulting from, directly or indirectly&#58; </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;the breach or violation of or inaccuracy in any representation or warranty made by the Company on the date of this Agreement or on the Closing Date contained in this Agreement (in each case, as such representation or warranty would read if all qualifications as to materiality, including each reference to the words &#8220;Material Adverse Effect,&#8221; &#8220;material&#8221; and &#8220;materiality&#8221; and all similar phrases and words, were deleted therefrom)&#59; </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;the breach or violation of any covenant or agreement of the Company contained in this Agreement or in any other document executed and delivered by the Company or any PreClosing Holders, as applicable, in connection with the consummation of the transactions contemplated hereby&#59; </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;any fraud by the Company under this Agreement&#59;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;any Action by a stockholder or former stockholder of the Company, or by any other Person, seeking to assert, or based upon&#58; (i) ownership or rights to ownership of any shares of Company Capital Stock, Company Options or any other Equity Interest in the Company or interest in the Final Merger Consideration, or (ii) any right of a stockholder or optionholder of the Company (other than the right to receive the Final Merger Consideration or the Option Consideration, as the case may be, pursuant to this Agreement), including any option, preemptive right or right to notice or to vote&#59; </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;any Actions or disputes with respect to (i) the allocation or payment among the Pre-Closing Holders and any other Person of any Final Merger Consideration or Option Consideration pursuant to the terms of this Agreement, (ii) any claim that the Payment Spreadsheet is not true, complete and correct in all respects, (iii) appraisal or dissenters&#8217; rights under DGCL and CGCL, (iv) any claims arising in connection with the Restructuring&#59; or (v) any other claims by any stockholder or former stockholder of the Company, in its capacity as such, against the Company or its directors, officers, or agents&#59;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(f)&#160;&#160;&#160;&#160;any Liabilities related to the Excluded Entities or the Excluded Business or the TeneoOne Sale, whether before or after the Closing, including the Excluded Employee Liabilities&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that with respect to TeneoOne, Liabilities under this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.2(f)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall not include Liabilities of the Company arising out of obligations of the Company arising after the Closing under any Listed Contracts&#59;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(g)&#160;&#160;&#160;&#160;any Pre-Closing Taxes&#59;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(h)&#160;&#160;&#160;&#160;any Taxes imposed on the Company or any of its Subsidiaries in connection with the TeneoOne Sale to the extent such Taxes are in excess of the Assumed Tax Liability&#59; and</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(i)&#160;&#160;&#160;&#160;the matters set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedule 11.2(i)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">85</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.3&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Indemnification of Pre-Closing Holders</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. From and after the Closing, each of the Pre-Closing Holders and each of their respective officers, directors, employees, shareholders, partners, members or other equity holders, agents and representatives (each, a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Holder Indemnified Party</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) shall be indemnified and held harmless by Buyer against such Pre-Closing Holder&#8217;s Pro-Rata Percentage of any and all Losses, whether or not involving a Third Party Claim, arising out of or directly or indirectly resulting from&#58;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;the breach or violation of or inaccuracy in any representation or warranty made by Buyer or Merger Sub on the date of this Agreement or on the Closing Date contained in this Agreement or in any other document executed and delivered by Buyer or Merger Sub in connection with the consummation of the transactions contemplated hereby (in each case, as such representation or warranty would read if all qualifications as to materiality, including each reference to the words &#8220;Material Adverse Effect,&#8221; &#8220;material&#8221; and &#8220;materiality&#8221; and all similar phrases and words, were deleted therefrom)&#59; or</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;the breach or violation of any covenant or agreement of Buyer or Merger Sub contained in this Agreement or in any other document executed and delivered by Buyer or Merger Sub in connection with the consummation of the transactions contemplated hereby, whether occurring before or at the Closing but not after the Closing.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.4&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Limits on Indemnification</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;Notwithstanding anything to the contrary contained in this Agreement, an Indemnifying Party shall not be liable for any claim for indemnification pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.2(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.3(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> unless and until the aggregate amount of indemnifiable Losses which may be recovered from the Indemnifying Party under </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.2(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.3(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, as the case may be, equals or exceeds four million five hundred thousand U.S. Dollars ($4,500,000) (such amount, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Deductible</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), after which the Indemnifying Party shall be liable for the full amount of all Losses and not only those in excess of the Deductible&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the foregoing limitations set forth in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.4(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall not apply to (i) breaches of, or inaccuracies in, the Fundamental Representations or (ii) Actions based upon fraud&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">further</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that claims for indemnification pursuant to any other provision of </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> are not subject to the monetary limitations set forth in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;Notwithstanding anything to the contrary contained in this Agreement, recovery from the Escrow Funds shall serve as the sole and exclusive source of indemnification from which the Buyer Indemnified Parties may collect Losses for which they are entitled to indemnification from the Pre-Closing Holders under </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.2(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the foregoing limitations set forth in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.4(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall not apply to (i) breaches of, or inaccuracies in, the Fundamental Representations, (ii) breaches of, or inaccuracies in, the Semi-Fundamental Representations or (C) Actions based upon fraud. Recovery from the Escrow Funds and the right of set-off under </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall serve as the sole and exclusive source of indemnification from which the Buyer Indemnified Parties may collect Losses for which they are entitled to indemnification from the Pre-Closing Holders for breaches of the Semi-Fundamental Representations under </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.2(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">86</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;For as long as there are funds available in the Escrow Funds to cover the Buyer Indemnified Parties&#8217; indemnifiable Losses, any and all Losses payable by the Pre-Closing Holders as Indemnifying Parties to the Buyer Indemnified Parties with respect to Losses for which they are entitled to indemnification from the Pre-Closing Holders under </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.2(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> will be paid in cash first out of the Escrow Funds, and in the event such Losses exceed, or are not paid and satisfied in full from, the Escrow Funds, the Buyer Indemnified Parties shall have the right to satisfy in full such Losses by means of exercising Buyer&#8217;s rights of set-off under </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.8</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Except for with respect to Fundamental Representations, Semi-Fundamental Representations and Actions based upon fraud, in no event shall a Pre-Closing Holder be liable for any Losses in excess of such Pre-Closing Holder&#8217;s Pro-Rata Percentage of the Escrow Funds for any Losses arising out of or resulting from Losses for which the Buyer Indemnified Parties are entitled to indemnification from the Pre-Closing Holders under </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.2(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(d)&#160;&#160;&#160;&#160;Except with respect to Actions based upon fraud committed by such Pre-Closing Holder or of which such Pre-Closing Holder had actual knowledge, in no event shall a Pre-Closing Holder be liable for any Losses with respect to Material Claims in excess of the portion of the Final Merger Consideration actually paid to such Pre-Closing Holder. </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(e)&#160;&#160;&#160;&#160;For purposes of this Agreement, &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Material Claims</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221; means Losses arising out of or relating to&#58; (i) any breaches of or inaccuracies in any Fundamental Representations or (ii) any matter for which indemnification may be sought under clauses (b) through (e) of </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(f)&#160;&#160;&#160;&#160;The amount of any Losses for which indemnification is provided under this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article XI</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall be net of any amounts actually recovered by the Indemnified Party under insurance policies with respect to such Losses (net of the present value of any increase in premiums actually imposed by the applicable insurance carrier as a result of the occurrence of the Loss, the Deductible and all costs and expenses incurred in recovering such insurance proceeds with respect to such Loss). </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(g)&#160;&#160;&#160;&#160;The right of Buyer to indemnification pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> will not be affected by any investigation conducted or knowledge acquired (or capable of being acquired) at any time, whether before or after the execution and delivery of this Agreement or the Closing, with respect to any accuracy of any representation or warranty, or performance of or compliance with any covenant or agreement herein.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(h)&#160;&#160;&#160;&#160;Notwithstanding anything to the contrary contained herein, in no event shall any amounts included in the calculation of Closing Date Funded Debt, Closing Date Net Working Capital, or Transaction Expenses be indemnifiable pursuant to this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article XI</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section&#160;8.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-style:italic;font-weight:400;line-height:120%">i.e.</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, no &#8220;double counting&#8221;). </font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(i)&#160;&#160;&#160;&#160;Except for the representations and warranties contained in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article&#160;IV</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, Buyer and Merger Sub acknowledge and agree that none of the Company or the Subsidiaries or their respective Representatives nor any other Person makes, and Buyer and Merger Sub are not relying on, any other express, implied or statutory representation or warranty with respect to the Company or the Subsidiaries or otherwise, including with respect to any projections, forecasts or other future results or outcomes for the Company and Subsidiaries.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">87</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.5&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Notice of Loss&#59; Third Party Claims</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;A claim for indemnification for any matter not involving a Third Party Claim may be asserted by written notice to the party from whom indemnification is sought.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;In the event that any Action shall be instituted or asserted by any third party in respect of which payment may be sought under </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.2</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.3</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> (regardless of the limitations set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">) (each, a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Third Party Claim</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), the Indemnified Party shall promptly cause written notice of the assertion of any Third Party Claim of which it has knowledge and that may be covered by this indemnity to be forwarded to the Indemnifying Party. The failure of the Indemnified Party to give reasonably prompt notice of any Third Party Claim shall not release, waive or otherwise affect the Indemnifying Party&#8217;s obligations with respect thereto except to the extent that the Indemnifying Party is actually prejudiced as a result of such failure. The Indemnifying Party shall have the right, at its sole option and expense, to be represented by counsel reasonably acceptable to the Indemnified Party and to defend against, negotiate, settle or otherwise deal with any Third Party Claim that relates to any Losses indemnified by it hereunder&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the Indemnifying Party may not assume control of defense to a Third Party Claim (i) involving any criminal proceeding, action, indictment, allegation or investigation, or in which relief other than monetary damages is sought, (ii) involving the alleged misuse, infringement, misappropriation or violation of any Intellectual Property, (iii) involving a purported class action, (iv) if the Indemnifying Party has not notified the Indemnified Party in writing that it will be liable to indemnify the Indemnified Party with respect to all Losses relating to such Third Party Claim subject to the limitations of </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or (v) if the Third Party Claim relates to the Company Intellectual Property. In addition, the Indemnifying Party may not maintain the defense of a Third Party Claim if it has failed to defend such Third Party Claim in good faith. If the Indemnifying Party elects to defend against, negotiate, settle or otherwise deal with any Third Party Claim that relates to any Losses indemnified by it hereunder, it shall within thirty (30) days (or sooner, if the nature of the Third Party Claim so requires) notify the Indemnified Party of its intent to do so. If the Indemnifying Party elects not to defend against, negotiate, settle or otherwise deal with any Third Party Claim that relates to any Losses indemnified against hereunder, or is not permitted to assume the defense of a Third Party Claim pursuant to the proviso to the third sentence of this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.5(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, the Indemnified Party may defend against, negotiate, settle or otherwise deal with such Third Party Claim, subject to the provisions below. If the Indemnifying Party shall assume the defense of any Third Party Claim pursuant to the terms of this Agreement, the Indemnified Party may participate, at his or its own expense, in the defense of such Third Party Claim&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that such Indemnified Party shall be entitled to participate in any such defense with separate counsel at the expense of the Indemnifying Party if (A)&#160;so requested by the Indemnifying Party to participate, (B) in the reasonable opinion of outside counsel to the Indemnified Party a conflict or potential conflict exists between the Indemnified Party and the Indemnifying Party that would make such separate representation advisable, or (C) in the reasonable opinion of outside counsel to the Indemnified Party there are legal defenses available to the Indemnified Party that are different from or additional to those available to Indemnifying Party&#59; and </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">further</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the Indemnifying Party shall not be required to pay for more than one such counsel (plus any appropriate local counsel) for all Indemnified Parties in </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">88</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">connection with any Third Party Claim. If after assuming the defense of a Third Party Claim the Indemnifying Party determines that it is not required to provide indemnification therefor, it shall promptly notify the Indemnified Party, cease to control the defense of such Third Party Claim, and shall nonetheless be responsible for all costs of defense incurred by it prior to such notice. The parties hereto agree to reasonably cooperate with each other in connection with the defense, negotiation or settlement of any such Third Party Claim. Notwithstanding anything in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> to the contrary, neither the Indemnifying Party nor the Indemnified Party shall, without the written consent of the other party, settle or compromise any Third Party Claim or permit a default or consent to entry of any Governmental Order unless (1) the claimant provides to such other party an unqualified release of the Indemnified Parties and Indemnifying Parties from all liability in respect of such Third Party Claim, (2) such settlement does not involve any injunctive relief binding upon the Indemnified Party or any of its Affiliates, (3) such settlement does not encumber any of the material assets of any Indemnified Party or impose any restriction or condition that would apply to or materially affect any Indemnified Party or the conduct of any Indemnified Party&#8217;s business and (4) such settlement does not involve any admission of liability or wrongdoing by any Indemnified Party or any of its Affiliates.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;In the event that the Indemnified Party conducts the defense of a Third Party Claim pursuant to this Section 11.5, the Indemnifying Party will remain responsible for any and all other Losses that the Indemnified Party may incur or suffer resulting from, arising out of, relating to, in the nature of or caused by the Third Party Claim to the fullest extent provided in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article XI</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.6&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Tax Treatment</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. To the extent permitted by Law, the parties hereto agree to treat all payments made under this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article XI</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, under </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, under any other indemnity provision contained in this Agreement, and for any misrepresentations or breach of warranties or covenants, as adjustments to the Final Merger Consideration and the Option Consideration for all Tax purposes.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.7&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Remedies</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. From and after the Closing, except as specifically provided herein, the sole and exclusive remedy of any Indemnified Party for any breach or failure to be true and correct, or alleged breach or failure to be true and correct, of any representation or warranty in this Agreement, shall be indemnification in accordance with this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article XI</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Notwithstanding the foregoing, this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.7</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> shall not operate to limit the rights of the parties to seek equitable remedies (including specific performance or injunctive relief) or any remedies available to it under applicable Law in the event of (a) a party&#8217;s failure to comply with its indemnification obligations hereunder or (b) fraud, willful breach or intentional misrepresentation committed by or on behalf of any party.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.8&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Set-Off</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. In addition to all other remedies contemplated herein and subject to the limitations set forth in </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> above, Buyer may set off, deduct or retain any amount due to the Pre-Closing Holders in respect of any bona fide claim for indemnification against any of the Pre-Closing Holders pursuant to this Agreement against any Milestone Payments. In the case of any claim for a breach of Semi-Fundamental Representations, the aggregate amount that Buyer may set-off shall equal one hundred and thirty five million U.S. Dollars ($135,000,000).</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">89</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.9&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">No Right of Contribution</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. No Pre-Closing Holder shall have any right of contribution against the Company or the Surviving Corporation with respect to any breach by the Company of any of its representations, warranties, covenants or agreements.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.10&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">No Circular Recovery</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Each Pre-Closing Holder hereby agrees that it will not make any claim for indemnification against Buyer, the Surviving Corporation or the Company by reason of the fact that such Pre-Closing Holder was a controlling Person, director, employee or representative of the Company or the Surviving Corporation or was serving as such for another Person at the request of Buyer or the Company (whether such claim is for Losses of any kind or otherwise and whether such claim is pursuant to any statute, organizational document, contractual obligation or otherwise) with respect to any claim brought by an Indemnified Party against any Pre-Closing Holder relating to this Agreement or any of the transactions contemplated hereby. With respect to any claim brought by an Indemnified Party against any Pre-Closing Holder relating to this Agreement and any of the transactions contemplated hereby, each Pre-Closing Holder expressly waives any right of subrogation, contribution, advancement, indemnification or other claim against the Company with respect to any amounts owed by such Pre-Closing Holder pursuant to this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article XI</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 11.11&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Release of Escrow Funds</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Subject to the further terms and conditions of the Escrow Agreement and this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article XI</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, Buyer and the Stockholder Representative shall execute joint written instructions to the Escrow Agent instructing the Escrow Agent to disburse the Escrow Funds in accordance with this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 11.11</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#58;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;On the date that is fifteen (15) months after the Closing (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Escrow Release Date</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), the amount remaining in the Escrow Funds </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">minus</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> the aggregate amount determined by Buyer in good faith to be held in reserve to satisfy any pending claims (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pending Claim Reserve</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) shall be released by the Escrow Agent to the Exchange Agent for distribution to the Pre-Closing Holders (</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that amounts payable in respect of Company Options shall be paid by to the Surviving Corporation for payment through its payroll system) in accordance with such Pre-Closing Holders&#8217; Pro-Rata Percentage of such amount.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;Following the Escrow Release Date, any Pending Claim Reserve shall remain in escrow until the resolution of all applicable claims to which such reserve relates. To the extent that such pending claim or claims are resolved in favor of Buyer, the amount determined to be owing to Buyer shall be paid to Buyer, with the amount of any such reserve remaining in the Escrow Funds after such payment to Buyer, if any, being released by the Escrow Agent to the Exchange Agent for distribution to the Pre-Closing Holders (</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that amounts payable in respect of Company Options shall be paid by to the Surviving Corporation for payment through its payroll system) in accordance with such Pre-Closing Holders&#8217; Pro-Rata Percentage of such amount.</font></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">ARTICLE XII.<br>STOCKHOLDER REPRESENTATIVE</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 12.1&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Designation and Replacement of Stockholder Representative</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The parties hereto have agreed that it is desirable to designate a representative to act on behalf of holders of the Pre-</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">90</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Closing Holders, as the exclusive agent and attorney-in-fact for and on behalf of such Persons as specified herein (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Stockholder Representative</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). By virtue of the approval of the Merger and this Agreement by the Pre-Closing Holders and without any further action of any of the Pre-Closing Holders or the Company, Company has designated Fortis Advisors LLC as the Stockholder Representative, and the receipt of the Requisite Stockholder Approval by the Company Stockholders shall constitute ratification and approval of such designation. The designation of any Person as the Stockholder Representative, and the powers, immunities and rights to indemnification granted to the Stockholder Representative Group hereunder&#58; (i) are and shall be considered a power of attorney coupled with an interest, and, except as set forth in this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Article&#160;XI</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, such designation is irrevocable and shall not be affected by the death, incapacity, illness, bankruptcy, dissolution or other inability to act of any of the Pre-Closing Holders, and (ii)&#160;shall survive the delivery of an assignment by any Pre-Closing Holder of the whole or any fraction of his, her or its interest in the Escrow Funds or Milestone Payments.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 12.2&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Authority and Rights of the Stockholder Representative&#59; Limitations on Liability</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The Stockholder Representative shall have such powers and authority as are necessary to carry out the functions assigned to it under this Agreement, the Escrow Agreement and the Stockholder Representative Engagement Agreement&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the Stockholder Representative shall have no obligation to act on behalf of the Pre-Closing Holders, except as expressly provided herein, in the Escrow Agreement and in the Stockholder Representative Engagement Agreement, and for purposes of clarity, there are no obligations of the Stockholder Representative in any ancillary agreement, schedule, exhibit or the Company Disclosure Schedules. Without limiting the generality of the foregoing, the Stockholder Representative shall have full power, authority and discretion to (a) give and receive notices and communications on behalf of the Pre-Closing Holders, (b) estimate and determine the amounts of Stockholder Representative Expenses and to pay such Stockholder Representative Expenses in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, (c) to resolve on behalf of the Pre-Closing Holders any disputes related to the occurrence of any Milestone or the payment of any Milestone Payment, including to commence litigation in accordance with the terms of this Agreement and to comply with Governmental Orders and awards of any arbitrators related thereto, and to settle any such disputes on behalf of the Pre-Closing Holders, and (d) after the Closing, negotiate and enter into amendments to this Agreement and the Escrow Agreement for and on behalf of the Pre-Closing Holders. All actions taken by the Stockholder Representative under this Agreement, the Escrow Agreement or the Stockholder Representative Engagement Agreement shall be binding upon the Pre-Closing Holders and their successors as if expressly confirmed and ratified in writing by each of them, and all defenses which may be available to any Pre-Closing Holder to contest, negate or disaffirm the action of the Stockholder Representative taken in good faith under this Agreement, the Escrow Agreement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%"> </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">or the Stockholder Representative Engagement Agreement are waived. The Stockholder Representative may resign at any time and may be removed or replaced by a majority vote of the Advisory Group. The immunities and rights to indemnification shall survive the resignation or removal of the Stockholder Representative or any member of the Advisory Group and the Closing and&#47;or any termination of this Agreement and the Escrow Agreement. Certain Pre-Closing Holders have entered into an engagement agreement (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Stockholder Representative Engagement Agreement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) with the Stockholder Representative to provide direction to the Stockholder Representative in connection with its services under this Agreement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">, </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">91</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">the Escrow Agreement and the Stockholder Representative Engagement Agreement (such Pre-Closing Holders, including their individual representatives, collectively hereinafter referred to as the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Advisory Group</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). Neither the Stockholder Representative nor its members, managers, directors, officers, contractors, agents and employees nor any member of the Advisory Group (collectively, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Stockholder Representative Group</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), shall have any liability to Buyer, the Company or any holder of Common Stock, Preferred Stock or Company Options with respect to actions taken or omitted to be taken in good faith in its capacity as the Stockholder Representative under this Agreement, the Escrow Agreement or the Stockholder Representative Engagement Agreement (except for those arising out of the Stockholder Representative&#8217;s gross negligence or willful misconduct). The Pre-Closing Holders acknowledge that the Stockholder Representative shall not be required to expend or risk its own funds or otherwise incur any financial liability in the exercise or performance of any of its powers, rights, duties or privileges or pursuant to this Agreement, the Escrow Agreement, the Stockholder Representative Engagement Agreement or the transactions contemplated hereby or thereby. The Stockholder Representative shall at all times be entitled to rely on any directions received from the Majority Holders&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the Stockholder Representative shall not be required to follow any such direction, and shall be under no obligation to take any action in its capacity as the Stockholder Representative, unless the Stockholder Representative is holding funds delivered to it under </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> and has been provided with other funds, security or indemnities which, in the sole determination of the Stockholder Representative, are sufficient to protect the Stockholder Representative against the costs, expenses and liabilities which may be incurred by the Stockholder Representative in responding to such direction or taking such action. The Stockholder Representative shall be entitled to engage such counsel, experts and other agents and consultants as it shall deem necessary in connection with exercising its powers and performing its function hereunder and (in the absence of bad faith on the part of the Stockholder Representative) shall be entitled to conclusively rely on the opinions and advice of such Persons. The Stockholder Representative shall be entitled to&#58; (i) rely upon the Payment Spreadsheet, (ii)&#160;rely upon any signature believed by it to be genuine, and (iii) reasonably assume that a signatory has proper authorization to sign on behalf of the applicable Pre-Closing Holder or other party. The Stockholder Representative shall be entitled to reimbursement for all Stockholder Representative Expenses first, from the Stockholder Representative Expense Fund, second from any distribution of the Escrow Funds or Milestone Payments otherwise distributable to the Pre-Closing Holders at the time of distribution, and third, directly from the Pre-Closing Holders. The Stockholder Representative Group shall be entitled to indemnification and defense by the Pre-Closing Holders and shall be held harmless against any loss, liability or Stockholder Representative Expenses arising out of actions taken or omitted to be taken in good faith in its capacity as the Stockholder Representative under this Agreement, the Escrow Agreement or the Stockholder Representative Engagement Agreement (except for those arising out of the Stockholder Representative&#8217;s gross negligence or willful misconduct), including the costs and expenses of investigation and defense of claims. In the event that the Stockholder Representative determines, in its sole and absolute discretion, that the funds paid to the Stockholder Representative pursuant to </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> exceed the Stockholder Representative Expenses, as soon as reasonably determined by the Stockholder Representative that the Stockholder Representative Expense Fund is no longer required to be withheld, the Stockholder Representative shall transfer such excess amount to the Escrow Agent solely for disbursement (or otherwise cause such excess </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">92</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">amount to be disbursed) to the Pre-Closing Holders as Final Merger Consideration in accordance with each Pre-Closing Holder&#8217;s Pro-Rata Percentage&#59; provided, however, that notwithstanding anything to the contrary in this Agreement or the Escrow Agreement, in no event shall such excess amount otherwise become payable to Buyer.</font></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:700;line-height:120%">ARTICLE XIII.<br>MISCELLANEOUS</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.1&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Waiver</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Any party to this Agreement may, at any time prior to the Closing, by action taken by its Board of Directors, or officers thereunto duly authorized, waive any of the terms or conditions of this Agreement or (without limiting </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 13.11</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">) agree to an amendment or modification to this Agreement by an agreement in writing executed in the same manner (but not necessarily by the same Persons) as this Agreement. No waiver by any of the parties hereto of any default, misrepresentation or breach of representation, warranty, covenant or other agreement hereunder, whether intentional or not, shall be deemed to extend to any prior or subsequent default, misrepresentation or breach or affect in any way any rights arising by virtue of any prior or subsequent such occurrence. No waiver by any of the parties of any of the provisions hereof shall be effective unless explicitly set forth in writing and executed by the party sought to be charged with such waiver.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.2&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Notices</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. All notices and other communications among the parties shall be in writing and shall be deemed to have been duly given (i) when delivered in person, (ii) when delivered after posting in the United States mail having been sent registered or certified mail return receipt requested, postage prepaid, (iii) when delivered by FedEx or other nationally recognized overnight delivery service, or (iv) when delivered by facsimile or email (in each case in this clause (iv), solely if receipt is confirmed), addressed as follows, provided that with respect to notices deliverable to the Stockholder Representative, such notices shall be delivered solely via email or facsimile&#58;</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;If to Buyer, Merger Sub or the Surviving Corporation, to&#58;</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Amgen Inc.</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">One Amgen Center Drive</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Thousand Oaks, California 91320-1799</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Attention&#58; Corporate Secretary</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Facsimile&#58; 805.499.6751</font></div><div style="padding-left:144pt"><font><br></font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">with a copy (which shall not constitute notice) to&#58;</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Latham &#38; Watkins LLP</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">650 Town Center Drive</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Costa Mesa, California 92626</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Attention&#58; Charles Ruck&#59; Daniel Rees</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Email&#58; </font><font style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">charles.ruck&#64;lw.com</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#59; </font><font style="color:#0000ff;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">daniel.rees&#64;lw.com</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> </font></div><div style="padding-left:144pt"><font><br></font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;If to the Company, prior to the Closing, to&#58;</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">93</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">TeneoBio, Inc.</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">7999 Gateway Blvd #320</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Newark, CA 94560<br>Attention&#58; Chief Executive Officer</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Email&#58; rbuelow&#64;teneobio.com</font></div><div style="padding-left:144pt"><font><br></font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">with copies (which shall not constitute notice) to&#58;</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Gunderson Dettmer Stough Villeneuve Franklin &#38; Hachigian, LLP</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">550 Allerton Street, Redwood City, CA 94063</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Attention&#58; Colin Chapman&#59; Michael Irvine</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Email&#58; cchapman&#64;gunder.com&#59; mirvine&#64;gunder.com </font></div><div style="padding-left:144pt"><font><br></font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(c)&#160;&#160;&#160;&#160;If to the Stockholder Representative, to&#58;</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Fortis Advisors LLC</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Attention&#58; Notices Department (Project Tuxedo)</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Email&#58; notices&#64;fortisrep.com</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Facsimile No.&#58; (858) 408-1843</font></div><div style="padding-left:144pt"><font><br></font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">with a copy (which shall not constitute notice) to&#58;</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Gunderson Dettmer Stough Villeneuve Franklin &#38; Hachigian, LLP</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">550 Allerton Street, Redwood City, CA 94063</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Attention&#58; Colin Chapman&#59; Michael Irvine</font></div><div style="padding-left:144pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Email&#58; cchapman&#64;gunder.com&#59; mirvine&#64;gunder.com </font></div><div style="margin-bottom:12pt"><font><br></font></div><div style="margin-bottom:12pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">or to such other address or addresses as the parties may from time to time designate in writing.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.3&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Assignment</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. No party hereto shall assign this Agreement or any part hereof without the prior written consent of the other parties&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that Buyer or Merger Sub may assign this Agreement or any part hereof to an Affiliate thereof without the consent of any other party hereto&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that Buyer or Merger Sub, as applicable, shall remain liable for any obligations so assigned. Subject to the foregoing, this Agreement shall be binding upon and inure to the benefit of the parties hereto and their respective successors and permitted assigns.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.4&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Rights of Third Parties</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Nothing expressed or implied in this Agreement is intended or shall be construed to confer upon or give any Person, other than the parties hereto, any right or remedies under or by reason of this Agreement. </font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.5&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Release</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. In consideration of each Pre-Closing Holder&#8217;s right to receive their applicable portion of the Final Merger Consideration, and as a condition and inducement to the Company&#8217;s, Buyer&#8217;s and Merger Sub&#8217;s willingness to enter into this Agreement, effective as of the Closing Date, each Pre-Closing Holder, on behalf of itself, himself or herself and each of its, his or her agents, trustees, beneficiaries, directors, officers, Affiliates, Subsidiaries, estate, successors, assigns, members and partners (each, a &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Holder Releasor</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), hereby (a)&#160;acknowledges, warrants and agrees that he, she or it has no claims against the Company, </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">94</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Buyer and&#47;or Surviving Corporation and their respective Affiliates, and each of their respective current and former officers, directors, employees, partners, members and advisors (collectively, the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Holder Releasees</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), and (b) irrevocably and unconditionally releases and forever discharges the Pre-Closing Holder Releasees of and from any and all actions, causes of action, suits, proceedings, judgments, debts, dues, claims and demands whatsoever, whether in law or in equity, which the Pre-Closing Holder Releasor may have against each of the Pre-Closing Holder Releasees, now or in the future, in each case, in respect of any cause, matter or thing relating to (i)&#160;such Pre-Closing Holder Releasor&#8217;s ownership or purported ownership of Pre-Closing Holder Releasor&#8217;s Company Capital Stock or other securities of the Company, (ii)&#160;the negotiation or execution of this Agreement or any of the other documents referenced in this Agreement or the consummation of the Merger and any transactions contemplated thereby, or (iii) any other matters related to the Company (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Pre-Closing Holder Released Claims</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;). Each Pre-Closing Holder Releasor acknowledges, warrants and agrees that he, she or it does not rely, and has not relied, on any representation or statement not set forth in this Agreement made by any representative of the Company or anyone else with regard to the subject matter, basis or effect of this release, and is familiar with Section 1542 of the Civil Code of the State of California (&#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 1542</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;), which provides as follows&#58; A GENERAL RELEASE DOES NOT EXTEND TO CLAIMS WHICH THE CREDITOR DOES NOT KNOW OR SUSPECT TO EXIST IN HIS OR HER FAVOR AT THE TIME OF EXECUTING THE RELEASE, WHICH IF KNOWN BY HIM OR HER MUST HAVE MATERIALLY AFFECTED HIS OR HER SETTLEMENT WITH THE DEBTOR. Notwithstanding the foregoing, this release shall not cover, and Pre-Closing Holder Released Claims do not include, (A) claims arising from the rights of such Pre-Closing Holder Releasor under this Agreement (including the right to receive any payments due to such Pre-Closing Holder Releasor as contemplated hereunder), (B) if such PreClosing Holder Releasor is an employee of the Company, such Pre-Closing Holder Releasor&#8217;s rights, if any, to accrued and unpaid salary or bonus due to such Pre-Closing Holder Releasor through the date hereof, vested employee benefits as of the date hereof, and business expenses incurred prior to the date hereof, (C) any rights of indemnification that a Pre-Closing Holder Releasor may have by reason of his or her status as a director, officer, or fiduciary of the Company, pursuant to the Company Charter, the Company Bylaws, or under applicable Law, subject to this Agreement, or (D) any other rights that cannot by Law be released by private agreement. Each Pre-Closing Holder Releasor hereby waives and relinquishes on behalf of himself, herself or itself, his, her or its heirs, executors, administrators and assigns any rights and benefits that such Pre-Closing Holder Releasor may have under Section 1542 or any similar statute or common law principle of any jurisdiction. Each Pre-Closing Holder Releasor acknowledges that he, she or it may hereafter discover facts in addition to or different from those that Pre-Closing Holder Releasor now knows or believes to be true with respect to the subject matter of this release, but it is Pre-Closing Holder Releasor&#8217;s intention to fully and finally and forever settle and release any and all Pre-Closing Holder Released Claims (other than such PreClosing Holder Released Claims expressly reserved and excluded herein) that do now exist, may exist or heretofore have existed with respect to the subject matter of this release. In furtherance of this intention, the releases contained herein shall be and remain in effect as full and complete general releases notwithstanding the discovery or existence of any such additional or different facts. This release is conditioned upon the consummation of the Merger as contemplated in herein and shall become null and void, and shall have no effect whatsoever, </font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">95</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">without any action on the part of any Person, upon termination of this Agreement in accordance with the terms thereof for any reason.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.6&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Expenses</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Each party hereto, other than the Stockholder Representative (whose expenses shall be paid out of funds paid to the Stockholder Representative under </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">), shall bear its own expenses incurred in connection with this Agreement and the transactions contemplated hereby whether or not such transactions shall be consummated, including all fees of its legal counsel, financial advisers and accountants&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">however</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the fees and expenses of the Independent Auditor, if any, shall be paid in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 3.4</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">further</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the parties hereto shall pay Transfer Taxes in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.5</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">further</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that Buyer shall pay all fees payable to the Antitrust Authorities in connection with the transactions contemplated by this Agreement in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 8.6(c)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">further</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that, in the event that the transactions contemplated hereby are not consummated, the Company shall reimburse the Stockholder Representative for all costs and expenses incurred by the Stockholder Representative in connection with the transactions contemplated hereby.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.7&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Governing Law</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. This Agreement, and all claims or causes of action based upon, arising out of, or related to this Agreement or the transactions contemplated hereby, shall be governed by, and construed in accordance with, the Laws of the State of Delaware, without giving effect to principles or rules of conflict of laws to the extent such principles or rules would require or permit the application of Laws of another jurisdiction.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.8&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Captions&#59; Counterparts</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The captions in this Agreement are for convenience only and shall not be considered a part of or affect the construction or interpretation of any provision of this Agreement. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. Counterparts and any other document required to be executed and delivered hereunder may be delivered via facsimile, electronic mail (including .pdf or any electronic signature complying with the U.S. federal ESIGN Act of 2000 (e.g., www.docusign.com)) or other transmission method and any counterpart or such document so delivered shall be deemed to have been duly and validly delivered and be valid and effective for all purposes.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.9&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Schedules, Exhibits and Annexes</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The Disclosure Schedules, Exhibits and Annexes referenced herein are a part of this Agreement as if fully set forth herein. All references herein to the Disclosure Schedules, Exhibits and Annexes shall be deemed references to such parts of this Agreement, unless the context shall otherwise require. Any disclosure made by a party in the Disclosure Schedules with reference to any section or schedule of this Agreement shall be deemed to be a disclosure with respect to all other sections or schedules to which the relevance of such disclosure is reasonably apparent. Certain information set forth in the Disclosure Schedules is included solely for informational purposes and may not be required to be disclosed pursuant to this Agreement. The disclosure of any information shall not be deemed to constitute an acknowledgment that such information is required to be disclosed in connection with the representations and warranties made in this Agreement, nor shall such information be deemed to establish a standard of materiality.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">96</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.10&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Entire Agreement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. This Agreement (together with the Disclosure Schedules, Exhibits and Annexes to this Agreement), the Escrow Agreement, and that certain Non-Disclosure Agreement, dated March 10, 2021, between Buyer and the Company (the &#8220;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Confidentiality Agreement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#8221;) constitute the entire agreement among the parties relating to the transactions contemplated hereby and supersede any other agreements, whether written or oral, that may have been made or entered into by or among any of the parties hereto or any of their respective Subsidiaries relating to the transactions contemplated hereby. No representations, warranties, covenants, understandings or agreements, oral or otherwise, relating to the transactions contemplated by this Agreement exist between the parties, except as expressly set forth in this Agreement, the Escrow Agreement, and the Confidentiality Agreement.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.11&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Amendments</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. This Agreement may be amended or modified in whole or in part, only by a duly authorized agreement in writing executed in the same manner as this Agreement and which makes reference to this Agreement. The approval of this Agreement by the stockholders of the Company shall not restrict the ability of the Board of Directors of the Company to terminate this Agreement in accordance with </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 10.1</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or to cause the Company to enter into an amendment to this Agreement pursuant to this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 13.11</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> to the extent permitted under Section&#160;251(d) of the DGCL.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.12&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Publicity</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The Company agrees that, from the date hereof through the Closing Date, no public release or announcement concerning the transactions contemplated hereby shall be issued or made by or on behalf of any party without the prior consent of Buyer, except the Company may make any disclosures or announcements necessary to comply with applicable Law or regulations. Buyer shall prepare, subject to the Company&#8217;s review and comment, a joint press release to be issued on or promptly (and in any event within two (2) Business Days) after the date of this Agreement. The Company agrees to keep the terms of this Agreement confidential, except to the extent and to the Persons to whom disclosure is required by applicable Law or securities exchange regulation or for purposes of compliance with financial reporting obligations&#59; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">, that the Company may disclose such terms to its employees, accountants, advisors and other representatives as necessary in connection with the ordinary conduct of businesses (so long as such Persons agree to, or are bound by contract or professional or fiduciary obligations to, keep the terms of this Agreement confidential and so long as the Company shall be responsible to the other parties hereto for breach of this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 13.12</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> or such confidentiality obligations by the recipients of its disclosure). </font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.13&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Severability</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. If any provision of this Agreement is held invalid or unenforceable by any court of competent jurisdiction, the other provisions of this Agreement shall remain in full force and effect. The parties further agree that if any provision contained herein is, to any extent, held invalid or unenforceable in any respect under the Laws governing this Agreement, they shall take any actions necessary to render the remaining provisions of this Agreement valid and enforceable to the fullest extent permitted by Law and, to the extent necessary, shall amend or otherwise modify this Agreement to replace any provision contained herein that is held invalid or unenforceable with a valid and enforceable provision giving effect to the intent of the parties.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">97</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.14&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Jurisdiction&#59; Waiver of Jury Trial</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(a)&#160;&#160;&#160;&#160;Any Action based upon, arising out of or related to this Agreement or the transactions contemplated hereby may be brought in the Delaware Chancery Court (or, if the Delaware Chancery Court shall be unavailable, any other court of the State of Delaware or, in the case of claims to which the federal courts have exclusive subject matter jurisdiction, any federal court of the United States of America sitting in the State of Delaware), and, in each case, appellate courts therefrom, and each of the parties irrevocably submits to the exclusive jurisdiction of each such court in any such Action, waives any objection it may now or hereafter have to personal jurisdiction, venue or to convenience of forum, agrees that all claims in respect of such Action shall be heard and determined only in any such court, and agrees not to bring any Action arising out of or relating to this Agreement or the transactions contemplated hereby in any other court. Nothing herein contained shall be deemed to affect the right of any party to serve process in any manner permitted by Law or to commence legal proceedings or otherwise proceed against any other party in any other jurisdiction, in each case, to enforce judgments obtained in any Action brought pursuant to this </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Section 13.14(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">(b)&#160;&#160;&#160;&#160;EACH PARTY HERETO HEREBY WAIVES, TO THE FULLEST EXTENT PERMITTED BY APPLICABLE LAW, ANY RIGHT IT MAY HAVE TO A TRIAL BY JURY IN RESPECT OF ANY ACTION ARISING OUT OF THIS AGREEMENT OR THE TRANSACTIONS CONTEMPLATED HEREBY. EACH PARTY HERETO (I) CERTIFIES THAT NO REPRESENTATIVE, AGENT OR ATTORNEY OF ANY OTHER PARTY HAS REPRESENTED, EXPRESSLY OR OTHERWISE, THAT SUCH PARTY WOULD NOT, IN THE EVENT OF ANY ACTION, SEEK TO ENFORCE THE FOREGOING WAIVER AND (II) ACKNOWLEDGES THAT IT AND THE OTHER PARTIES HERETO HAVE BEEN INDUCED TO ENTER INTO THIS AGREEMENT BY, AMONG OTHER THINGS, THE MUTUAL WAIVER AND CERTIFICATIONS IN THIS </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">SECTION 13.14</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">.</font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.15&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Enforcement</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. The parties hereto agree that irreparable damage would occur, and that the parties would not have any adequate remedy at law, in the event that any of the provisions of this Agreement were not performed in accordance with their specific terms or were otherwise breached. It is accordingly agreed that the parties shall be entitled to an injunction or injunctions to prevent breaches of this Agreement and to specifically enforce the terms and provisions of this Agreement, without proof of actual damages or otherwise, in addition to any other remedy to which any party is entitled at law or in equity. Each party agrees to waive any requirement for the securing or posting of any bond in connection with such remedy. The parties further agree not to assert that a remedy of specific enforcement is unenforceable, invalid, contrary to law or inequitable for any reason, nor to assert that a remedy of monetary damages would provide an adequate remedy. To the extent any party hereto brings an Action to enforce specifically the performance of the terms and provisions of this Agreement (other than an Action to enforce specifically any provision that by its terms requires performance after the Closing or expressly survives termination of this Agreement), the Outside Date shall automatically be extended to (a) the twentieth (20th) Business Day following the resolution of such Action or (b) such other time period established by the court presiding over such Action.</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">98</font></div><div><font><br></font></div></div></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.16&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Tax Advice</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Each party hereto acknowledges and agrees that it has not received and is not relying upon Tax advice from any other party, and that it has and will continue to consult with its own advisors with respect to Taxes. </font></div><div style="margin-bottom:12pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Section 13.17&#160;&#160;&#160;&#160;</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">Privilege</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">. Buyer and the Company agree that the attorney-client privilege of the Company and its Subsidiaries shall continue to belong to them following the Closing and shall not pass to or be claimed by any Pre-Closing Holder (and any attorney-client privilege of the Pre-Closing Holders shall continue to belong to the Pre-Closing Holders following the Closing and shall not pass to or be claimed by the Company or its Subsidiaries), </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">provided</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> that, as to all communications prior to the Closing among outside legal counsel to the Company (including Gunderson Dettmer Stough Villeneuve Franklin &#38; Hachigian, LLP or Hogan Lovells US LLP) and the Company and the Pre-Closing Holders and their respective Affiliates that relate to the transactions contemplated by this Agreement and are subject to the attorney-client privilege and the exception of client confidence, none of Acquirer, the Company or any of their Affiliates shall disclose (nor shall any Pre-Closing Holder or any of its Affiliates be required to disclose) any such communications in any legal proceeding in support of a claim by any of them against the Stockholder Representative, any Pre-Closing Holder any of their Affiliates (unless such communication is no longer subject to attorney-client privilege for reasons other than the actions of Parent, the Company or any of their Affiliates).</font></div><div style="margin-bottom:12pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">&#91;Remainder of page intentionally left blank&#93;</font></div><div><font><br></font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">99</font></div><div><font><br></font></div></div></div><div id="ie89a4d87abd349778894081552e8cb68_10"></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> </font></div></div><div style="margin-bottom:12pt;text-align:justify;text-indent:36pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">IN WITNESS WHEREOF the parties have hereunto caused this Agreement to be duly executed as of the date first above written.</font></div><div style="margin-bottom:36pt;padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">TENEOBIO, INC.</font></div><div style="padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">By&#58; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">&#47;s&#47; Roland Buelow&#160;&#160;&#160;&#160;</font></div><div style="padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Name&#58; Roland Buelow</font></div><div style="margin-bottom:36pt;padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Title&#58;   Chief Executive Officer</font></div><div style="margin-bottom:36pt;padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">TUXEDO MERGER SUB, INC.</font></div><div style="padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">By&#58; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">&#47;s&#47; Jonathan P. Graham&#160;&#160;&#160;&#160;</font></div><div style="padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Name&#58; Jonathan P. Graham</font></div><div style="margin-bottom:36pt;padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Title&#58;   Executive Vice President, General Counsel and Secretary</font></div><div style="margin-bottom:36pt;padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">AMGEN INC.</font></div><div style="padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">By&#58; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">&#47;s&#47; Robert A. Bradway&#160;&#160;&#160;&#160;</font></div><div style="padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Name&#58; Robert A. Bradway</font></div><div style="margin-bottom:36pt;padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Title&#58;   Chairman of the Board, Chief Executive Officer and President</font></div><div style="padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">FORTIS ADVISORS LLC, solely in its capacity as Stockholder Representative hereunder</font></div><div style="padding-left:216pt"><font><br></font></div><div style="padding-left:216pt"><font><br></font></div><div style="padding-left:216pt"><font><br></font></div><div style="padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">By&#58; </font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%;text-decoration:underline">&#47;s&#47; Ryan Simkin&#160;&#160;&#160;&#160;</font></div><div style="padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Name&#58; Ryan Simkin</font></div><div style="margin-bottom:36pt;padding-left:216pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%">Title&#58;   Managing Director</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div><font><br></font></div></div></div><div id="ie89a4d87abd349778894081552e8cb68_13"></div><hr style="page-break-after:always"><div style="min-height:72pt;width:100%"><div><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:12pt;font-weight:400;line-height:120%"> </font></div></div><div style="text-align:center"><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">List of Exhibits and Annexes Omitted from the Agreement and Plan of Merger</font></div><div style="text-align:center"><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Referenced in Exhibit 2.7 Above</font></div><div style="text-align:center"><font><br></font></div><div><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Pursuant to Regulation&#160;S-K,&#160;Item 601(b)(2), the Exhibits and Annexes to the Agreement and Plan of Merger referenced in Exhibit 2.7 above, as listed below, have not been filed. The Registrant agrees to furnish supplementally a copy of any omitted Exhibit or Annex to the Securities and Exchange Commission (the &#8220;Commission&#8221;) upon request&#59; provided, however, that the Registrant may request confidential treatment of omitted items.</font></div><div><font><br></font></div><div><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;text-decoration:underline">Exhibits</font></div><div><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Exhibit A &#8211; Form of Written Consent</font></div><div><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Exhibit B &#8211; Form of Certificate of Merger</font></div><div><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Exhibit C &#8211; Form of Certificate of Incorporation</font></div><div><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Exhibit D &#8211; Form of Escrow Agreement</font></div><div><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Exhibit E &#8211; Forms of Second Amended and Restated Assignment and License Agreements</font></div><div><font><br></font></div><div><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;text-decoration:underline">Annexes</font></div><div><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Annex A &#8211; TNB-585</font></div><div><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Annex B &#8211; Pro Forma Payment Spreadsheet</font></div><div><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Annex C &#8211; Eligible Programs</font></div><div><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Annex D &#8211; Restructuring Step Plan</font></div><div><font style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Annex E &#8211; Sample Net Working Capital Statement</font></div><div style="height:72pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div><font><br></font></div></div></div></body></html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-31
<SEQUENCE>3
<FILENAME>amgn-ex31_2021930xq3.htm
<DESCRIPTION>RULE 13A-14(A) CERTIFICATIONS
<TEXT>
<!DOCTYPE html PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/html4/loose.dtd"><html><head>
<!-- Document created using Wdesk -->
<!-- Copyright 2021 Workiva -->
<title>Document</title></head><body><div id="ia9f20d4119b94025be8ed0aac24fdea9_1"></div><div style="min-height:42.75pt;width:100%"><div style="text-align:right"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">Exhibit 31</font></div></div><div style="margin-bottom:8pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">CERTIFICATIONS</font></div><div style="margin-bottom:8pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">I, Robert A. Bradway, Chairman of the Board, Chief Executive Officer and President of Amgen Inc., certify that&#58;</font></div><div style="margin-bottom:8pt;padding-left:18pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">1.</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:10.5pt">I have reviewed this Quarterly Report on Form 10-Q of Amgen Inc.&#59;</font></div><div style="margin-bottom:8pt;padding-left:18pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">2.</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:10.5pt">Based on my knowledge, this quarterly report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this quarterly report&#59;</font></div><div style="margin-bottom:8pt;padding-left:18pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">3.</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:10.5pt">Based on my knowledge, the financial statements, and other financial information included in this quarterly report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this quarterly report&#59;</font></div><div style="margin-bottom:8pt;padding-left:18pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">4.</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:10.5pt">The registrant&#8217;s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have&#58;</font></div><div style="margin-bottom:8pt;padding-left:36pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:6.91pt">Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this quarterly report is being prepared&#59;</font></div><div style="margin-bottom:8pt;padding-left:36pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:6.34pt">Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles&#59;</font></div><div style="margin-bottom:8pt;padding-left:36pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(c)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:6.91pt">Evaluated the effectiveness of the registrant&#8217;s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this quarterly report based on such evaluation&#59; and</font></div><div style="margin-bottom:8pt;padding-left:36pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(d)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:6.34pt">Disclosed in this quarterly report any change in the registrant&#8217;s internal control over financial reporting that occurred during the registrant&#8217;s most recent fiscal quarter (the registrant&#8217;s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant&#8217;s internal control over financial reporting&#59; and</font></div><div style="margin-bottom:8pt;padding-left:18pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">5.</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:10.5pt">The registrant&#8217;s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant&#8217;s auditors and the audit committee of the registrant&#8217;s board of directors (or persons performing the equivalent functions)&#58;</font></div><div style="margin-bottom:8pt;padding-left:36pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:6.91pt">All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant&#8217;s ability to record, process, summarize and report financial information&#59; and</font></div><div style="margin-bottom:8pt;padding-left:36pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:6.34pt">Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant&#8217;s internal control over financial reporting.</font></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.707%"><tr><td style="width:1.0%"></td><td style="width:48.900%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:48.900%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Date&#58;  November 2, 2021</font></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#47;s&#47; ROBERT A. BRADWAY</font></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Robert A. Bradway</font></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:bottom"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Chairman of the Board,</font></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:bottom"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Chief Executive Officer and President</font></td></tr></table></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">1</font></div></div></div><div id="ia9f20d4119b94025be8ed0aac24fdea9_4"></div><hr style="page-break-after:always"><div style="min-height:42.75pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:8pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">CERTIFICATIONS</font></div><div style="margin-bottom:8pt;text-align:justify"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">I, Peter H. Griffith, Executive Vice President and Chief Financial Officer of Amgen Inc., certify that&#58;</font></div><div style="margin-bottom:8pt;padding-left:18pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">1.</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:10.5pt">I have reviewed this Quarterly Report on Form 10-Q of Amgen Inc.&#59;</font></div><div style="margin-bottom:8pt;padding-left:18pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">2.</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:10.5pt">Based on my knowledge, this quarterly report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this quarterly report&#59;</font></div><div style="margin-bottom:8pt;padding-left:18pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">3.</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:10.5pt">Based on my knowledge, the financial statements, and other financial information included in this quarterly report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this quarterly report&#59;</font></div><div style="margin-bottom:8pt;padding-left:18pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">4.</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:10.5pt">The registrant&#8217;s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have&#58;</font></div><div style="margin-bottom:8pt;padding-left:36pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:6.91pt">Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this quarterly report is being prepared&#59;</font></div><div style="margin-bottom:8pt;padding-left:36pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:6.34pt">Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles&#59;</font></div><div style="margin-bottom:8pt;padding-left:36pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(c)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:6.91pt">Evaluated the effectiveness of the registrant&#8217;s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this quarterly report based on such evaluation&#59; and</font></div><div style="margin-bottom:8pt;padding-left:36pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(d)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:6.34pt">Disclosed in this quarterly report any change in the registrant&#8217;s internal control over financial reporting that occurred during the registrant&#8217;s most recent fiscal quarter (the registrant&#8217;s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant&#8217;s internal control over financial reporting&#59; and</font></div><div style="margin-bottom:8pt;padding-left:18pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">5.</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:10.5pt">The registrant&#8217;s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant&#8217;s auditors and the audit committee of the registrant&#8217;s board of directors (or persons performing the equivalent functions)&#58;</font></div><div style="margin-bottom:8pt;padding-left:36pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(a)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:6.91pt">All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant&#8217;s ability to record, process, summarize and report financial information&#59; and</font></div><div style="margin-bottom:8pt;padding-left:36pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(b)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:6.34pt">Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant&#8217;s internal control over financial reporting.</font></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.707%"><tr><td style="width:1.0%"></td><td style="width:48.900%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:48.900%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Date&#58;  November 2, 2021</font></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:bottom"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#47;s&#47; PETER H. GRIFFITH</font></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Peter H. Griffith</font></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Executive Vice President and Chief Financial Officer</font></td></tr></table></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">2</font></div></div></div></body></html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-32
<SEQUENCE>4
<FILENAME>amgn-ex32_2021930xq3.htm
<DESCRIPTION>SECTION 1350 CERTIFICATIONS
<TEXT>
<!DOCTYPE html PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/html4/loose.dtd"><html><head>
<!-- Document created using Wdesk -->
<!-- Copyright 2021 Workiva -->
<title>Document</title></head><body><div id="i0e4ad25039ac4c65b9d3d6da1c1f7552_1"></div><div style="min-height:42.75pt;width:100%"><div style="text-align:right"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">Exhibit 32</font></div></div><div style="margin-bottom:8pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">Certification of Chief Executive Officer</font></div><div style="margin-bottom:8pt;text-align:justify;text-indent:24.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Pursuant to 18 U.S.C. &#167; 1350, as created by Section&#160;906 of the Sarbanes-Oxley Act of 2002, the undersigned officer of Amgen Inc. (the &#8220;Company&#8221;) hereby certifies that&#58;</font></div><div style="margin-bottom:8pt;padding-left:40.5pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(i)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:8.57pt">the accompanying Quarterly Report on Form 10-Q of the Company for the period ended September 30, 2021 (the &#8220;Report&#8221;) fully complies with the requirements of Section&#160;13(a) or Section&#160;15(d), as applicable, of the Securities Exchange Act of 1934, as amended&#59; and</font></div><div style="margin-bottom:8pt;padding-left:40.5pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(ii)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:5.8pt">information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.</font></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.707%"><tr><td style="width:1.0%"></td><td style="width:48.900%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:48.900%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Date&#58;  November 2, 2021</font></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#47;s&#47; ROBERT A. BRADWAY</font></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Robert A. Bradway</font></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Chairman of the Board,</font></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Chief Executive Officer and President</font></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:24.75pt"><font><br></font></div><div style="margin-bottom:8pt;text-align:justify;text-indent:24.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">A signed original of this written statement required by Section&#160;906 of the Sarbanes-Oxley Act of 2002 (&#8220;Section 906&#8221;), or other document authenticating, acknowledging, or otherwise adopting the signature that appears in typed form within the electronic version of this written statement required by Section&#160;906, has been provided to Amgen Inc. and will be retained by Amgen Inc. and furnished to the Securities and Exchange Commission or its staff upon request.</font></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">1</font></div></div></div><div id="i0e4ad25039ac4c65b9d3d6da1c1f7552_4"></div><hr style="page-break-after:always"><div style="min-height:42.75pt;width:100%"><div><font><br></font></div></div><div style="margin-bottom:8pt;text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:120%">Certification of Chief Financial Officer</font></div><div style="margin-bottom:8pt;text-align:justify;text-indent:24.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Pursuant to 18 U.S.C. &#167; 1350, as created by Section&#160;906 of the Sarbanes-Oxley Act of 2002, the undersigned officer of Amgen Inc. (the &#8220;Company&#8221;) hereby certifies that&#58;</font></div><div style="margin-bottom:8pt;padding-left:40.5pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(i)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:8.57pt">the accompanying Quarterly Report on Form 10-Q of the Company for the period ended September 30, 2021 (the &#8220;Report&#8221;) fully complies with the requirements of Section&#160;13(a) or Section&#160;15(d), as applicable, of the Securities Exchange Act of 1934, as amended&#59; and</font></div><div style="margin-bottom:8pt;padding-left:40.5pt;text-align:justify;text-indent:-18pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">(ii)</font><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%;padding-left:5.8pt">information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.</font></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.707%"><tr><td style="width:1.0%"></td><td style="width:48.900%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:48.900%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Date&#58;  November 2, 2021</font></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#47;s&#47; PETER H. GRIFFITH</font></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Peter H. Griffith</font></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Executive Vice President and Chief Financial Officer</font></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:24.75pt"><font><br></font></div><div style="margin-bottom:8pt;text-align:justify;text-indent:24.75pt"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">A signed original of this written statement required by Section&#160;906 of the Sarbanes-Oxley Act of 2002 (&#8220;Section 906&#8221;), or other document authenticating, acknowledging, or otherwise adopting the signature that appears in typed form within the electronic version of this written statement required by Section&#160;906, has been provided to Amgen Inc. and will be retained by Amgen Inc. and furnished to the Securities and Exchange Commission or its staff upon request.</font></div><div style="height:42.75pt;position:relative;width:100%"><div style="bottom:0;position:absolute;width:100%"><div style="text-align:center"><font style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">2</font></div></div></div></body></html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.SCH
<SEQUENCE>5
<FILENAME>amgn-20210930.xsd
<DESCRIPTION>XBRL TAXONOMY EXTENSION SCHEMA DOCUMENT
<TEXT>
<XBRL>
<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2021 Workiva-->
<!--r:e5235af6-2e2c-44cc-b741-bc0b6d42fa8f,g:5c86b37c-c57f-4c71-acc2-468d6efa37c1-->
<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:amgn="http://www.amgen.com/20210930" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:dtr-types="http://www.xbrl.org/dtr/type/2020-01-21" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" attributeFormDefault="unqualified" elementFormDefault="qualified" targetNamespace="http://www.amgen.com/20210930">
  <xs:import namespace="http://fasb.org/srt/2021-01-31" schemaLocation="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd"/>
  <xs:import namespace="http://fasb.org/us-gaap/2021-01-31" schemaLocation="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd"/>
  <xs:import namespace="http://www.w3.org/1999/xlink" schemaLocation="http://www.xbrl.org/2003/xlink-2003-12-31.xsd"/>
  <xs:import namespace="http://www.xbrl.org/2003/instance" schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd"/>
  <xs:import namespace="http://www.xbrl.org/2003/linkbase" schemaLocation="http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd"/>
  <xs:import namespace="http://www.xbrl.org/dtr/type/2020-01-21" schemaLocation="https://www.xbrl.org/dtr/type/2020-01-21/types.xsd"/>
  <xs:import namespace="http://xbrl.org/2005/xbrldt" schemaLocation="http://www.xbrl.org/2005/xbrldt-2005.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/country/2021" schemaLocation="https://xbrl.sec.gov/country/2021/country-2021.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/currency/2021" schemaLocation="https://xbrl.sec.gov/currency/2021/currency-2021.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/dei/2021" schemaLocation="https://xbrl.sec.gov/dei/2021/dei-2021.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/exch/2021" schemaLocation="https://xbrl.sec.gov/exch/2021/exch-2021.xsd"/>
  <xs:annotation>
    <xs:appinfo>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="amgn-20210930_lab.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="amgn-20210930_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="amgn-20210930_cal.xml" xlink:role="http://www.xbrl.org/2003/role/calculationLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="amgn-20210930_def.xml" xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:type="simple"/>
      <link:roleType id="CoverPage" roleURI="http://www.amgen.com/role/CoverPage">
        <link:definition>0001001 - Document - Cover Page</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CondensedConsolidatedStatementsofComprehensiveIncome" roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome">
        <link:definition>1001002 - Statement - Condensed Consolidated Statements of Comprehensive Income</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CondensedConsolidatedStatementsofIncome" roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome">
        <link:definition>1002003 - Statement - Condensed Consolidated Statements of Income</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CondensedConsolidatedBalanceSheets" roleURI="http://www.amgen.com/role/CondensedConsolidatedBalanceSheets">
        <link:definition>1003004 - Statement - Condensed Consolidated Balance Sheets</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CondensedConsolidatedBalanceSheetsParenthetical" roleURI="http://www.amgen.com/role/CondensedConsolidatedBalanceSheetsParenthetical">
        <link:definition>1004005 - Statement - Condensed Consolidated Balance Sheets (Parenthetical)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CondensedConsolidatedStatementsofStockholdersEquity" roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity">
        <link:definition>1005006 - Statement - Condensed Consolidated Statements of Stockholders' Equity</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CondensedConsolidatedStatementsofStockholdersEquityParenthetical" roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquityParenthetical">
        <link:definition>1006007 - Statement - Condensed Consolidated Statements of Stockholders' Equity (Parenthetical)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CondensedConsolidatedStatementsofCashFlows" roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows">
        <link:definition>1007008 - Statement - Condensed Consolidated Statements of Cash Flows</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Summaryofsignificantaccountingpolicies" roleURI="http://www.amgen.com/role/Summaryofsignificantaccountingpolicies">
        <link:definition>2101101 - Disclosure - Summary of significant accounting policies</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SummaryofsignificantaccountingpoliciesPolicies" roleURI="http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesPolicies">
        <link:definition>2202201 - Disclosure - Summary of significant accounting policies (Policies)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SummaryofsignificantaccountingpoliciesDetails" roleURI="http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesDetails">
        <link:definition>2403401 - Disclosure - Summary of significant accounting policies (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BusinessCombinationsandAssetAcquisitions" roleURI="http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitions">
        <link:definition>2104102 - Disclosure - Business Combinations and Asset Acquisitions</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BusinessCombinationsandAssetAcquisitionsTables" roleURI="http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsTables">
        <link:definition>2305301 - Disclosure - Business Combinations and Asset Acquisitions (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BusinessCombinationsandAssetAcquisitionsDetails" roleURI="http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails">
        <link:definition>2406402 - Disclosure - Business Combinations and Asset Acquisitions (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Revenues" roleURI="http://www.amgen.com/role/Revenues">
        <link:definition>2107103 - Disclosure - Revenues</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenuesTables" roleURI="http://www.amgen.com/role/RevenuesTables">
        <link:definition>2308302 - Disclosure - Revenues (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenuesDetails" roleURI="http://www.amgen.com/role/RevenuesDetails">
        <link:definition>2409403 - Disclosure - Revenues (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Incometaxes" roleURI="http://www.amgen.com/role/Incometaxes">
        <link:definition>2110104 - Disclosure - Income taxes</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IncometaxesDetails" roleURI="http://www.amgen.com/role/IncometaxesDetails">
        <link:definition>2411404 - Disclosure - Income taxes (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Earningspershare" roleURI="http://www.amgen.com/role/Earningspershare">
        <link:definition>2112105 - Disclosure - Earnings per share</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="EarningspershareTables" roleURI="http://www.amgen.com/role/EarningspershareTables">
        <link:definition>2313303 - Disclosure - Earnings per share (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="EarningspershareDetails" roleURI="http://www.amgen.com/role/EarningspershareDetails">
        <link:definition>2414405 - Disclosure - Earnings per share (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Collaborations" roleURI="http://www.amgen.com/role/Collaborations">
        <link:definition>2115106 - Disclosure - Collaborations</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CollaborationsDetails" roleURI="http://www.amgen.com/role/CollaborationsDetails">
        <link:definition>2416406 - Disclosure - Collaborations (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Investments" roleURI="http://www.amgen.com/role/Investments">
        <link:definition>2117107 - Disclosure - Investments</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InvestmentsTables" roleURI="http://www.amgen.com/role/InvestmentsTables">
        <link:definition>2318304 - Disclosure - Investments (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InvestmentsDetails" roleURI="http://www.amgen.com/role/InvestmentsDetails">
        <link:definition>2419407 - Disclosure - Investments (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InvestmentsFairValuesbyClassificationDetails" roleURI="http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails">
        <link:definition>2420408 - Disclosure - Investments (Fair Values by Classification) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InvestmentsAvailableforsaleInvestmentsDetailsTextual" roleURI="http://www.amgen.com/role/InvestmentsAvailableforsaleInvestmentsDetailsTextual">
        <link:definition>2421409 - Disclosure - Investments (Available-for-sale Investments) (Details Textual)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InvestmentsFairValuesbyContractualMaturityDetails" roleURI="http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails">
        <link:definition>2422410 - Disclosure - Investments (Fair Values by Contractual Maturity) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InvestmentsEquitySecuritiesDetailsTextual" roleURI="http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual">
        <link:definition>2423411 - Disclosure - Investments (Equity Securities) (Details Textual)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails" roleURI="http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails">
        <link:definition>2424412 - Disclosure - Investments Investments (Limited Partnership Investments) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Inventories" roleURI="http://www.amgen.com/role/Inventories">
        <link:definition>2125108 - Disclosure - Inventories</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InventoriesTables" roleURI="http://www.amgen.com/role/InventoriesTables">
        <link:definition>2326305 - Disclosure - Inventories (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InventoriesDetails" roleURI="http://www.amgen.com/role/InventoriesDetails">
        <link:definition>2427413 - Disclosure - Inventories (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Goodwillandotherintangibleassets" roleURI="http://www.amgen.com/role/Goodwillandotherintangibleassets">
        <link:definition>2128109 - Disclosure - Goodwill and other intangible assets</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandotherintangibleassetsTables" roleURI="http://www.amgen.com/role/GoodwillandotherintangibleassetsTables">
        <link:definition>2329306 - Disclosure - Goodwill and other intangible assets (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandotherintangibleassetsGoodwillRollForwardDetails" roleURI="http://www.amgen.com/role/GoodwillandotherintangibleassetsGoodwillRollForwardDetails">
        <link:definition>2430414 - Disclosure - Goodwill and other intangible assets (Goodwill Roll Forward) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails" roleURI="http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails">
        <link:definition>2431415 - Disclosure - Goodwill and other intangible assets (Identifiable Intangible Assets) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandotherintangibleassetsDetailsTextual" roleURI="http://www.amgen.com/role/GoodwillandotherintangibleassetsDetailsTextual">
        <link:definition>2432416 - Disclosure - Goodwill and other intangible assets (Details Textual)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Financingarrangements" roleURI="http://www.amgen.com/role/Financingarrangements">
        <link:definition>2133110 - Disclosure - Financing arrangements</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FinancingarrangementsTables" roleURI="http://www.amgen.com/role/FinancingarrangementsTables">
        <link:definition>2334307 - Disclosure - Financing arrangements (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails" roleURI="http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails">
        <link:definition>2435417 - Disclosure - Financing arrangements (Principal Amounts and Carrying Value of Long-term Borrowings) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FinancingarrangementsDetailsTextual" roleURI="http://www.amgen.com/role/FinancingarrangementsDetailsTextual">
        <link:definition>2436418 - Disclosure - Financing arrangements (Details Textual)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FinancingarrangementsinterestrateswapstextualinterimonlyDetails" roleURI="http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails">
        <link:definition>2437419 - Disclosure - Financing arrangements (interest rate swaps textual interim only) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Stockholdersequity" roleURI="http://www.amgen.com/role/Stockholdersequity">
        <link:definition>2138111 - Disclosure - Stockholders' equity</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockholdersequityTables" roleURI="http://www.amgen.com/role/StockholdersequityTables">
        <link:definition>2339308 - Disclosure - Stockholders' equity (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockholdersequityShareRepurchaseProgramDetails" roleURI="http://www.amgen.com/role/StockholdersequityShareRepurchaseProgramDetails">
        <link:definition>2440420 - Disclosure - Stockholders' equity (Share Repurchase Program) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockholdersequityDetailsTextualDetails" roleURI="http://www.amgen.com/role/StockholdersequityDetailsTextualDetails">
        <link:definition>2441421 - Disclosure - Stockholders' equity (Details Textual) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockholdersequityComponentsofAOCIDetails" roleURI="http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails">
        <link:definition>2442422 - Disclosure - Stockholders' equity (Components of AOCI) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockholdersequityReclassificationsoutofAOCIDetails" roleURI="http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails">
        <link:definition>2443423 - Disclosure - Stockholders' equity (Reclassifications out of AOCI) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Fairvaluemeasurement" roleURI="http://www.amgen.com/role/Fairvaluemeasurement">
        <link:definition>2144112 - Disclosure - Fair value measurement</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FairvaluemeasurementTables" roleURI="http://www.amgen.com/role/FairvaluemeasurementTables">
        <link:definition>2345309 - Disclosure - Fair value measurement (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FairvaluemeasurementDetails" roleURI="http://www.amgen.com/role/FairvaluemeasurementDetails">
        <link:definition>2446424 - Disclosure - Fair value measurement (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FairvaluemeasurementDetailsTextual" roleURI="http://www.amgen.com/role/FairvaluemeasurementDetailsTextual">
        <link:definition>2447425 - Disclosure - Fair value measurement (Details Textual)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SubsequentEvents" roleURI="http://www.amgen.com/role/SubsequentEvents">
        <link:definition>2148113 - Disclosure - Subsequent Events</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SubsequentEventsTables" roleURI="http://www.amgen.com/role/SubsequentEventsTables">
        <link:definition>2349310 - Disclosure - Subsequent Events (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SubsequentEventsDetails" roleURI="http://www.amgen.com/role/SubsequentEventsDetails">
        <link:definition>2450426 - Disclosure - Subsequent Events (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Derivativeinstruments" roleURI="http://www.amgen.com/role/Derivativeinstruments">
        <link:definition>2151114 - Disclosure - Derivative instruments</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DerivativeinstrumentsTables" roleURI="http://www.amgen.com/role/DerivativeinstrumentsTables">
        <link:definition>2352311 - Disclosure - Derivative instruments (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DerivativeinstrumentsDetailsTextual" roleURI="http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual">
        <link:definition>2453427 - Disclosure - Derivative instruments (Details Textual)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DerivativeinstrumentsCrosscurrencySwapsDetails" roleURI="http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails">
        <link:definition>2454428 - Disclosure - Derivative instruments (Cross-currency Swaps) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails" roleURI="http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails">
        <link:definition>2455429 - Disclosure - Derivative instruments (Effective Portion of Unrealized Gain (Loss)) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails" roleURI="http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails">
        <link:definition>2456430 - Disclosure - Derivative instruments (Hedged Liabilities and Cumulative Amount) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails" roleURI="http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails">
        <link:definition>2457431 - Disclosure - Derivative instruments (Summary of Income and Expense Line Items) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DerivativeinstrumentsFairValueofDerivativesDetails" roleURI="http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails">
        <link:definition>2458432 - Disclosure - Derivative instruments (Fair Value of Derivatives) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Contingenciesandcommitments" roleURI="http://www.amgen.com/role/Contingenciesandcommitments">
        <link:definition>2159115 - Disclosure - Contingencies and commitments</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ContingenciesandcommitmentsDetails" roleURI="http://www.amgen.com/role/ContingenciesandcommitmentsDetails">
        <link:definition>2460433 - Disclosure - Contingencies and commitments (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Subsequentevents" roleURI="http://www.amgen.com/role/Subsequentevents">
        <link:definition>2161116 - Disclosure - Subsequent events</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SubsequenteventsDetails" roleURI="http://www.amgen.com/role/SubsequenteventsDetails">
        <link:definition>2462434 - Disclosure - Subsequent events (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
    </xs:appinfo>
  </xs:annotation>
  <xs:element id="amgn_OtherShortTermInterestBearingSecuritiesMember" abstract="true" name="OtherShortTermInterestBearingSecuritiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember" abstract="true" name="TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_A2030And2021NoteHedgesMember" abstract="true" name="A2030And2021NoteHedgesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_FivePointSevenFivePercentNotesDue2040Member" abstract="true" name="FivePointSevenFivePercentNotesDue2040Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember" abstract="true" name="TwoPointSixZeroNotesDueTwoZeroTwoSixMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_SensiparAntitrustClassActionsMember" abstract="true" name="SensiparAntitrustClassActionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember" abstract="true" name="ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_RecoveryOfDirectCostsReceivable" abstract="false" name="RecoveryOfDirectCostsReceivable" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_SixPointThreeSevenFivePercentNotesDue2037Member" abstract="true" name="SixPointThreeSevenFivePercentNotesDue2037Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_BeiGeneMember" abstract="true" name="BeiGeneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_IncreaseDecreaseInNoncurrentTaxLiability" abstract="false" name="IncreaseDecreaseInNoncurrentTaxLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_TwoPointTwoZeroNotesDue2020Member" abstract="true" name="TwoPointTwoZeroNotesDue2020Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_LossContingencyAppealPeriod" abstract="false" name="LossContingencyAppealPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="amgn_A1.250SeniorNotesDue2022Member" abstract="true" name="A1.250SeniorNotesDue2022Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_OtezlaMember" abstract="true" name="OtezlaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember" abstract="true" name="TwoPercentEuroNotesDueTwoThousandTwentySixMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_AvailableForSalesInvestmentsMember" abstract="true" name="AvailableForSalesInvestmentsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_EquityMethodInvestmentChangeInCarryingValueOther" abstract="false" name="EquityMethodInvestmentChangeInCarryingValueOther" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_OtherNotesDue2097Member" abstract="true" name="OtherNotesDue2097Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_XgevaMember" abstract="false" name="XgevaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_ThreePointFourFivePercentNotesDue2020Member" abstract="true" name="ThreePointFourFivePercentNotesDue2020Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_FourPointFiveZeroPercentNotesDue2020Member" abstract="true" name="FourPointFiveZeroPercentNotesDue2020Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_ThreePointTwoZeroNotesDue2027Member" abstract="true" name="ThreePointTwoZeroNotesDue2027Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_ScheduleOfIntangibleAssetsTableTextBlock" abstract="false" name="ScheduleOfIntangibleAssetsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="amgn_CorporateDebtSecuritiesFinancialMember" abstract="true" name="CorporateDebtSecuritiesFinancialMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_FourPointOneZeroPercentNotesDue2021Member" abstract="true" name="FourPointOneZeroPercentNotesDue2021Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_ThreePointThreeSevenFivePercentNotesDue2050Member" abstract="true" name="ThreePointThreeSevenFivePercentNotesDue2050Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_NatureOfOperationsPolicyTextBlock" abstract="false" name="NatureOfOperationsPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember" abstract="true" name="AccruedLiabilitiesOtherNonCurrentLiabilitiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_IdentifiableIntangibleAssetsAccumulatedAmortization" abstract="false" name="IdentifiableIntangibleAssetsAccumulatedAmortization" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax" abstract="false" name="OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_HospiraMember" abstract="true" name="HospiraMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_OtherCurrentNoncurrentAssetsMember" abstract="true" name="OtherCurrentNoncurrentAssetsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_EquityMethodInvestmentChangeInCarryingValue" abstract="false" name="EquityMethodInvestmentChangeInCarryingValue" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_A300NotesDue20523002052NotesMember" abstract="true" name="A300NotesDue20523002052NotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_TwoPointZeroPercent2032NotesMemberMember" abstract="true" name="TwoPointZeroPercent2032NotesMemberMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_KANJINTIPatentLitigationMember" abstract="true" name="KANJINTIPatentLitigationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments" abstract="false" name="RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember" abstract="true" name="ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_BasisOfPresentationPolicyTextBlock" abstract="false" name="BasisOfPresentationPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions" abstract="false" name="BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_KyprolisMember" abstract="true" name="KyprolisMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_RepatriationTaxOnProposedAdditionalTax" abstract="false" name="RepatriationTaxOnProposedAdditionalTax" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_OtherProductsMember" abstract="true" name="OtherProductsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_FivePointSixFivePercentNotesDue2042Member" abstract="true" name="FivePointSixFivePercentNotesDue2042Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_NumberOfAssertedPatents" abstract="false" name="NumberOfAssertedPatents" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="amgn_TeneobioIncMember" abstract="true" name="TeneobioIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember" abstract="true" name="FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_NeulastaMember" abstract="false" name="NeulastaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member" abstract="true" name="FivePointFiveZeroPercentPoundSterlingNotesDue2026Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember" abstract="true" name="TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent" abstract="false" name="PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue" abstract="false" name="AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_NeumoraTherapeuticsIncMember" abstract="true" name="NeumoraTherapeuticsIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_LossContingencyPatentsExpiredNumber" abstract="false" name="LossContingencyPatentsExpiredNumber" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="amgn_ThreePointSixTwoFivePercentNotesDue2022Member" abstract="true" name="ThreePointSixTwoFivePercentNotesDue2022Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_A2.00SeniorNotesDue2026Member" abstract="true" name="A2.00SeniorNotesDue2026Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_IdentifiableIntangibleAssetsGross" abstract="false" name="IdentifiableIntangibleAssetsGross" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_DebtExchangeAdditionalCashConsideration" abstract="false" name="DebtExchangeAdditionalCashConsideration" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_CorporateDebtSecuritiesOtherMember" abstract="true" name="CorporateDebtSecuritiesOtherMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_TwoPointEightZeroPercent2041NotesMember" abstract="true" name="TwoPointEightZeroPercent2041NotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_StockRepurchaseProgramTableTextBlock" abstract="false" name="StockRepurchaseProgramTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember" abstract="true" name="OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_OtezlaANDAPatentLitigationMember" abstract="true" name="OtezlaANDAPatentLitigationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock" abstract="false" name="ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="amgn_NovartisPharmaAGMember" abstract="true" name="NovartisPharmaAGMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue" abstract="false" name="AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_FivePointThreeSevenFivePercentNotesDue2043Member" abstract="true" name="FivePointThreeSevenFivePercentNotesDue2043Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_LitigationSettlementDamagesSoughtValue" abstract="false" name="LitigationSettlementDamagesSoughtValue" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_DerivativeInstrumentNameDomain" abstract="true" name="DerivativeInstrumentNameDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_BasicAndDilutedEarningPerShareAbstract" abstract="true" name="BasicAndDilutedEarningPerShareAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember" abstract="true" name="TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_LongTermDebtCurrentMaturitiesMember" abstract="true" name="LongTermDebtCurrentMaturitiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_AlternativeInvestmentNetGainLoss" abstract="false" name="AlternativeInvestmentNetGainLoss" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_ProposedAdditionalIncomeTax" abstract="false" name="ProposedAdditionalIncomeTax" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember" abstract="true" name="AcquiredResearchAndDevelopmentTechnologyRightsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock" abstract="false" name="FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="amgn_CrossCurrencySwapContractsMember" abstract="true" name="CrossCurrencySwapContractsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract" abstract="true" name="DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="amgn_HedgedLiabilityDiscontinuedFairValueHedge" abstract="false" name="HedgedLiabilityDiscontinuedFairValueHedge" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember" abstract="true" name="FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_ForeignCurrencyAndCrossCurrencySwapsMember" abstract="true" name="ForeignCurrencyAndCrossCurrencySwapsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_FourPercentPoundSterlingNotesDue2029Member" abstract="true" name="FourPercentPoundSterlingNotesDue2029Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent" abstract="false" name="OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_EnbrelMember" abstract="false" name="EnbrelMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract" abstract="true" name="FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember" abstract="true" name="OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock" abstract="false" name="ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="amgn_FivePrimeTherapeuticsIncMember" abstract="true" name="FivePrimeTherapeuticsIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_KyprolisANDAPatentLitigationMember" abstract="true" name="KyprolisANDAPatentLitigationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_OnePointSixFivePercent2028NotesMember" abstract="true" name="OnePointSixFivePercent2028NotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember" abstract="true" name="TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_CorporateDebtSecuritiesIndustrialMember" abstract="true" name="CorporateDebtSecuritiesIndustrialMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity" abstract="false" name="EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_LossContingencyNumberOfLawsuits" abstract="false" name="LossContingencyNumberOfLawsuits" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="amgn_UpFrontPayment" abstract="false" name="UpFrontPayment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="amgn_TwoPointThreeZeroPercentNotesDue2031Member" abstract="true" name="TwoPointThreeZeroPercentNotesDue2031Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_ThreePointSixTwoFivePercentNotesDue2024Member" abstract="true" name="ThreePointSixTwoFivePercentNotesDue2024Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_KyowaKirinCoLtdMember" abstract="true" name="KyowaKirinCoLtdMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_ThreePointOneFivePercentNotesDue2040Member" abstract="true" name="ThreePointOneFivePercentNotesDue2040Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember" abstract="true" name="FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_ProliaMember" abstract="false" name="ProliaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_AccumulatedOtherAdjustmentAttributabletoParentMember" abstract="true" name="AccumulatedOtherAdjustmentAttributabletoParentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_PatentTrialAndAppealBoardPatentChallengesMember" abstract="true" name="PatentTrialAndAppealBoardPatentChallengesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_DerivativeInstrumentNameAxis" abstract="true" name="DerivativeInstrumentNameAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember" abstract="true" name="TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract" abstract="true" name="FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="amgn_FivePointOneFivePercentNotesDue2041Member" abstract="true" name="FivePointOneFivePercentNotesDue2041Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_FloatingRateNotesDue2020Member" abstract="true" name="FloatingRateNotesDue2020Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_HumiraBiosimilarAntitrustClassActionsMember" abstract="true" name="HumiraBiosimilarAntitrustClassActionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember" abstract="true" name="OnePointEightFivePercentNotesDueTwoZeroTwoOneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember" abstract="true" name="OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_DerivativeAssetsFairValueDisclosureAbstract" abstract="true" name="DerivativeAssetsFairValueDisclosureAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="amgn_ThreePointEightSevenFivePercentNotesDue2021Member" abstract="true" name="ThreePointEightSevenFivePercentNotesDue2021Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount" abstract="false" name="DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="amgn_SixPointFourZeroPercentNotesDue2039Member" abstract="true" name="SixPointFourZeroPercentNotesDue2039Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_TwoPointSixFiveNotesDue2022Member" abstract="true" name="TwoPointSixFiveNotesDue2022Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_SixPointNineZeroPercentNotesDue2038Member" abstract="true" name="SixPointNineZeroPercentNotesDue2038Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_AranespMember" abstract="false" name="AranespMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_TwoPointFourFivePercentNotesDue2030Member" abstract="true" name="TwoPointFourFivePercentNotesDue2030Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_FourPointNineFivePercentNotesDue2041Member" abstract="true" name="FourPointNineFivePercentNotesDue2041Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="amgn_RepathaevolocumabMember" abstract="true" name="RepathaevolocumabMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.CAL
<SEQUENCE>6
<FILENAME>amgn-20210930_cal.xml
<DESCRIPTION>XBRL TAXONOMY EXTENSION CALCULATION LINKBASE DOCUMENT
<TEXT>
<XBRL>
<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2021 Workiva-->
<!--r:e5235af6-2e2c-44cc-b741-bc0b6d42fa8f,g:5c86b37c-c57f-4c71-acc2-468d6efa37c1-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome" xlink:type="simple" xlink:href="amgn-20210930.xsd#CondensedConsolidatedStatementsofComprehensiveIncome"/>
  <link:calculationLink xlink:role="http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_905c7484-b7e9-413a-ba02-aefda68e488d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_51ae9f8f-1c89-4d55-9f5e-b9e34c2c1c5e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_905c7484-b7e9-413a-ba02-aefda68e488d" xlink:to="loc_us-gaap_NetIncomeLoss_51ae9f8f-1c89-4d55-9f5e-b9e34c2c1c5e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_7ea38bef-9015-4069-829d-a7b00ec658de" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_905c7484-b7e9-413a-ba02-aefda68e488d" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_7ea38bef-9015-4069-829d-a7b00ec658de" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_e5246028-03e8-4642-b095-6fbabda0cc5a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_0d284709-d2dc-48a5-9ff1-6eb53de3965f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_e5246028-03e8-4642-b095-6fbabda0cc5a" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_0d284709-d2dc-48a5-9ff1-6eb53de3965f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_c59438dd-2a36-4922-838c-7bc06e5aa494" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_e5246028-03e8-4642-b095-6fbabda0cc5a" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_c59438dd-2a36-4922-838c-7bc06e5aa494" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_0db8ab4c-5d7e-4736-9f93-71e38df84db8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_e5246028-03e8-4642-b095-6fbabda0cc5a" xlink:to="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_0db8ab4c-5d7e-4736-9f93-71e38df84db8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent_5e1ced3a-0f22-4018-9cf6-178c96a7136a" xlink:href="amgn-20210930.xsd#amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_e5246028-03e8-4642-b095-6fbabda0cc5a" xlink:to="loc_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent_5e1ced3a-0f22-4018-9cf6-178c96a7136a" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome" xlink:type="simple" xlink:href="amgn-20210930.xsd#CondensedConsolidatedStatementsofIncome"/>
  <link:calculationLink xlink:role="http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_debb46e6-e136-4840-9477-ac03b6151e38" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_e6b6c632-62e8-4c19-a63c-508b590ae98e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_debb46e6-e136-4840-9477-ac03b6151e38" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_e6b6c632-62e8-4c19-a63c-508b590ae98e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses_95cd7807-2583-4156-98b2-71b3fa9da417" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostsAndExpenses"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_debb46e6-e136-4840-9477-ac03b6151e38" xlink:to="loc_us-gaap_CostsAndExpenses_95cd7807-2583-4156-98b2-71b3fa9da417" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses_f84a30a5-2607-41f3-8019-39eab483766f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostsAndExpenses"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_fe7b1db6-7da6-4d6f-817c-3cfd41e97eeb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_f84a30a5-2607-41f3-8019-39eab483766f" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_fe7b1db6-7da6-4d6f-817c-3cfd41e97eeb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherGeneralExpense_7e3b721c-3046-42de-9688-a4262a1e1577" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherGeneralExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_f84a30a5-2607-41f3-8019-39eab483766f" xlink:to="loc_us-gaap_OtherGeneralExpense_7e3b721c-3046-42de-9688-a4262a1e1577" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost_1b64853b-74f0-4c40-831b-8108aa25ffca" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_f84a30a5-2607-41f3-8019-39eab483766f" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost_1b64853b-74f0-4c40-831b-8108aa25ffca" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_f073ceb7-761b-4325-9fd4-e81c9f3fae9f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_f84a30a5-2607-41f3-8019-39eab483766f" xlink:to="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_f073ceb7-761b-4325-9fd4-e81c9f3fae9f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_84d181c6-70c4-4e61-94ef-c3ac799643cc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_f84a30a5-2607-41f3-8019-39eab483766f" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_84d181c6-70c4-4e61-94ef-c3ac799643cc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_41831895-76c0-4501-9315-627e79e3a6b6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_4597b2e7-3f4d-4ab6-983d-eaac99f66335" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_41831895-76c0-4501-9315-627e79e3a6b6" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_4597b2e7-3f4d-4ab6-983d-eaac99f66335" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_5f4c65f1-8e89-4f69-977b-7bdc927f4f1f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_41831895-76c0-4501-9315-627e79e3a6b6" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_5f4c65f1-8e89-4f69-977b-7bdc927f4f1f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_1181acd1-b760-468a-b7b6-a067918b3dee" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_fc1c4e1e-db75-462f-a7c8-2ca538b5b62a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_1181acd1-b760-468a-b7b6-a067918b3dee" xlink:to="loc_us-gaap_OperatingIncomeLoss_fc1c4e1e-db75-462f-a7c8-2ca538b5b62a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebt_2140ec52-827c-46bb-992d-90811e0cd1c0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestExpenseDebt"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_1181acd1-b760-468a-b7b6-a067918b3dee" xlink:to="loc_us-gaap_InterestExpenseDebt_2140ec52-827c-46bb-992d-90811e0cd1c0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_33444565-b1f3-4c9e-8189-f29c2a02e854" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NonoperatingIncomeExpense"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_1181acd1-b760-468a-b7b6-a067918b3dee" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_33444565-b1f3-4c9e-8189-f29c2a02e854" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/CondensedConsolidatedBalanceSheets" xlink:type="simple" xlink:href="amgn-20210930.xsd#CondensedConsolidatedBalanceSheets"/>
  <link:calculationLink xlink:role="http://www.amgen.com/role/CondensedConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_faad6d63-3de8-44d1-a799-adc6e66e2044" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStocksIncludingAdditionalPaidInCapital_3a13a9d9-f779-4a54-9c3b-08a078104cc6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStocksIncludingAdditionalPaidInCapital"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_faad6d63-3de8-44d1-a799-adc6e66e2044" xlink:to="loc_us-gaap_CommonStocksIncludingAdditionalPaidInCapital_3a13a9d9-f779-4a54-9c3b-08a078104cc6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_3b26e72f-de62-4d84-9219-e1e7b4a4be61" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_faad6d63-3de8-44d1-a799-adc6e66e2044" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_3b26e72f-de62-4d84-9219-e1e7b4a4be61" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_3f844a43-e5b6-4f1d-8539-678ca4d7a1a4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_faad6d63-3de8-44d1-a799-adc6e66e2044" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_3f844a43-e5b6-4f1d-8539-678ca4d7a1a4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_0f749027-7f17-45ba-a050-6df7da5767fd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_db380083-70cb-49d3-8aa1-dd34a577c2c9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_0f749027-7f17-45ba-a050-6df7da5767fd" xlink:to="loc_us-gaap_LiabilitiesCurrent_db380083-70cb-49d3-8aa1-dd34a577c2c9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_5a7cade7-f18e-48e6-a84c-c5c26b11f6f9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_0f749027-7f17-45ba-a050-6df7da5767fd" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_5a7cade7-f18e-48e6-a84c-c5c26b11f6f9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent_7684a815-1b69-4750-bf02-dc606ca0883c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilityForUncertainTaxPositionsNoncurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_0f749027-7f17-45ba-a050-6df7da5767fd" xlink:to="loc_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent_7684a815-1b69-4750-bf02-dc606ca0883c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_02e752e8-c6bd-440c-8caf-44511c6d25df" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_0f749027-7f17-45ba-a050-6df7da5767fd" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_02e752e8-c6bd-440c-8caf-44511c6d25df" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_553e7402-06ab-4e82-b1f6-bb9ad22caedb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_0f749027-7f17-45ba-a050-6df7da5767fd" xlink:to="loc_us-gaap_StockholdersEquity_553e7402-06ab-4e82-b1f6-bb9ad22caedb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_74b39304-7e54-44aa-83ac-4d92cd8cf7f4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_0f749027-7f17-45ba-a050-6df7da5767fd" xlink:to="loc_us-gaap_CommitmentsAndContingencies_74b39304-7e54-44aa-83ac-4d92cd8cf7f4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_5578c402-b0b5-464f-9c06-6377435a1821" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_3207ef83-142b-4864-b697-d4634b52a633" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_5578c402-b0b5-464f-9c06-6377435a1821" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_3207ef83-142b-4864-b697-d4634b52a633" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_b58397a9-ae18-427a-942c-548635822c33" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_5578c402-b0b5-464f-9c06-6377435a1821" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_b58397a9-ae18-427a-942c-548635822c33" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_92707a0b-8846-4c89-8be4-09ec84a28b14" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_5578c402-b0b5-464f-9c06-6377435a1821" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_92707a0b-8846-4c89-8be4-09ec84a28b14" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_c19a62c2-e7a0-43a2-b564-97e93f8b2bdd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryNet"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_5578c402-b0b5-464f-9c06-6377435a1821" xlink:to="loc_us-gaap_InventoryNet_c19a62c2-e7a0-43a2-b564-97e93f8b2bdd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsCurrent_6a5afec3-bdf1-49e4-b970-5ad21a627612" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherAssetsCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_5578c402-b0b5-464f-9c06-6377435a1821" xlink:to="loc_us-gaap_OtherAssetsCurrent_6a5afec3-bdf1-49e4-b970-5ad21a627612" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_20778ec6-1533-4505-9449-e82d49976625" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_3548ba51-3cab-4f34-ac8d-87df3f3223cf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_20778ec6-1533-4505-9449-e82d49976625" xlink:to="loc_us-gaap_AssetsCurrent_3548ba51-3cab-4f34-ac8d-87df3f3223cf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_8256f15f-417d-470d-9558-ab1ef6c65945" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_20778ec6-1533-4505-9449-e82d49976625" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_8256f15f-417d-470d-9558-ab1ef6c65945" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_07efdfbd-55e8-4047-a9e7-0885f8a389f1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_20778ec6-1533-4505-9449-e82d49976625" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_07efdfbd-55e8-4047-a9e7-0885f8a389f1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_b30c559f-ef84-4b98-a438-0700ebab099f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_20778ec6-1533-4505-9449-e82d49976625" xlink:to="loc_us-gaap_Goodwill_b30c559f-ef84-4b98-a438-0700ebab099f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_4189ff52-dfcf-4349-bec7-2af7afe5b985" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_20778ec6-1533-4505-9449-e82d49976625" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_4189ff52-dfcf-4349-bec7-2af7afe5b985" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_ffa8677c-5d0f-4bb2-af76-f80df6222c19" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_549f958c-79e0-40de-8c07-e290f6e8eb4b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_ffa8677c-5d0f-4bb2-af76-f80df6222c19" xlink:to="loc_us-gaap_AccountsPayableCurrent_549f958c-79e0-40de-8c07-e290f6e8eb4b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_65221eea-7a46-4c3f-a6dc-3a38292ec706" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_ffa8677c-5d0f-4bb2-af76-f80df6222c19" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_65221eea-7a46-4c3f-a6dc-3a38292ec706" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_b345a132-ccb7-46f5-b867-ed6cb93e99b4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_ffa8677c-5d0f-4bb2-af76-f80df6222c19" xlink:to="loc_us-gaap_LongTermDebtCurrent_b345a132-ccb7-46f5-b867-ed6cb93e99b4" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="simple" xlink:href="amgn-20210930.xsd#CondensedConsolidatedStatementsofCashFlows"/>
  <link:calculationLink xlink:role="http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_24de26f4-d21c-41a1-bf28-f2b16501c4b4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_d69578d7-8d5b-4d98-abe5-4915d11350a0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_24de26f4-d21c-41a1-bf28-f2b16501c4b4" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_d69578d7-8d5b-4d98-abe5-4915d11350a0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_a2889444-70dd-4060-91f8-62957cbf1891" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_24de26f4-d21c-41a1-bf28-f2b16501c4b4" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_a2889444-70dd-4060-91f8-62957cbf1891" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireEquityMethodInvestments_30c89670-43f8-4998-a8b7-daebb8e447f7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireEquityMethodInvestments"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_24de26f4-d21c-41a1-bf28-f2b16501c4b4" xlink:to="loc_us-gaap_PaymentsToAcquireEquityMethodInvestments_30c89670-43f8-4998-a8b7-daebb8e447f7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_54eb9399-16c8-41c0-a3e5-ff357365e5d2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_24de26f4-d21c-41a1-bf28-f2b16501c4b4" xlink:to="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_54eb9399-16c8-41c0-a3e5-ff357365e5d2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireMarketableSecurities_13e0aad4-a668-44ac-b3bf-ddb6c74148a2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireMarketableSecurities"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_24de26f4-d21c-41a1-bf28-f2b16501c4b4" xlink:to="loc_us-gaap_PaymentsToAcquireMarketableSecurities_13e0aad4-a668-44ac-b3bf-ddb6c74148a2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_ab3d0562-c85a-412b-b518-712a2b408668" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_24de26f4-d21c-41a1-bf28-f2b16501c4b4" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_ab3d0562-c85a-412b-b518-712a2b408668" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_a4a07686-b4f3-46f6-af56-8f4f014d2bc5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsForProceedsFromOtherInvestingActivities"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_24de26f4-d21c-41a1-bf28-f2b16501c4b4" xlink:to="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_a4a07686-b4f3-46f6-af56-8f4f014d2bc5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_60b8f29d-9617-459a-9ef5-9ef8de830c66" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_fcb2d169-ffe1-4622-8144-9faccecaa2f3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_60b8f29d-9617-459a-9ef5-9ef8de830c66" xlink:to="loc_us-gaap_NetIncomeLoss_fcb2d169-ffe1-4622-8144-9faccecaa2f3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_e3bc4665-2474-457b-8ca5-196fb1c67772" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_60b8f29d-9617-459a-9ef5-9ef8de830c66" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_e3bc4665-2474-457b-8ca5-196fb1c67772" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxesAndTaxCredits_7b974e2f-5135-4abf-8f1d-3a768ba2d0cb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DeferredIncomeTaxesAndTaxCredits"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_60b8f29d-9617-459a-9ef5-9ef8de830c66" xlink:to="loc_us-gaap_DeferredIncomeTaxesAndTaxCredits_7b974e2f-5135-4abf-8f1d-3a768ba2d0cb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_e5481295-e5d8-4e1c-bfbb-6c85297fac87" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_60b8f29d-9617-459a-9ef5-9ef8de830c66" xlink:to="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_e5481295-e5d8-4e1c-bfbb-6c85297fac87" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoncashIncomeExpense_7399c11f-0c4c-48d7-a2ea-10e421cf1db4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherNoncashIncomeExpense"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_60b8f29d-9617-459a-9ef5-9ef8de830c66" xlink:to="loc_us-gaap_OtherNoncashIncomeExpense_7399c11f-0c4c-48d7-a2ea-10e421cf1db4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_b3e1c474-cac9-429b-afed-e7b3fbb426b5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_60b8f29d-9617-459a-9ef5-9ef8de830c66" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_b3e1c474-cac9-429b-afed-e7b3fbb426b5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_eb9a831d-5c36-474c-8873-c17577060532" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInInventories"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_60b8f29d-9617-459a-9ef5-9ef8de830c66" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_eb9a831d-5c36-474c-8873-c17577060532" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_3d14c5e0-f4b9-45ce-8de7-3fe103d45f59" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_60b8f29d-9617-459a-9ef5-9ef8de830c66" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_3d14c5e0-f4b9-45ce-8de7-3fe103d45f59" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_ae53e917-cd91-4c10-8c01-6d44707751bb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_60b8f29d-9617-459a-9ef5-9ef8de830c66" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_ae53e917-cd91-4c10-8c01-6d44707751bb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable_2ddfe19f-8900-458b-aa1c-87bed879e61a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_60b8f29d-9617-459a-9ef5-9ef8de830c66" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable_2ddfe19f-8900-458b-aa1c-87bed879e61a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_IncreaseDecreaseInNoncurrentTaxLiability_1fbabbc7-4647-4067-a3d8-36424be88312" xlink:href="amgn-20210930.xsd#amgn_IncreaseDecreaseInNoncurrentTaxLiability"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_60b8f29d-9617-459a-9ef5-9ef8de830c66" xlink:to="loc_amgn_IncreaseDecreaseInNoncurrentTaxLiability_1fbabbc7-4647-4067-a3d8-36424be88312" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_b131d1da-8f8d-406d-8865-c43d4a218e51" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingLiabilities"/>
    <link:calculationArc order="12" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_60b8f29d-9617-459a-9ef5-9ef8de830c66" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_b131d1da-8f8d-406d-8865-c43d4a218e51" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_c62c7c8a-d834-4b48-9d75-fda47df9868d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_7eec7635-8c94-4f24-a306-700ade1a1cac" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromIssuanceOfLongTermDebt"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_c62c7c8a-d834-4b48-9d75-fda47df9868d" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_7eec7635-8c94-4f24-a306-700ade1a1cac" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_d5eda838-baa6-40ff-abb8-cdc20bf05243" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_c62c7c8a-d834-4b48-9d75-fda47df9868d" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_d5eda838-baa6-40ff-abb8-cdc20bf05243" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_b59323db-9faa-446b-be6d-689692531aad" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_c62c7c8a-d834-4b48-9d75-fda47df9868d" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_b59323db-9faa-446b-be6d-689692531aad" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDividendsCommonStock_10be3a03-600d-4aac-82c8-625bdf7a3d7b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsOfDividendsCommonStock"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_c62c7c8a-d834-4b48-9d75-fda47df9868d" xlink:to="loc_us-gaap_PaymentsOfDividendsCommonStock_10be3a03-600d-4aac-82c8-625bdf7a3d7b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_10970b84-e9b1-43ad-93f2-f8ccb0b98525" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromPaymentsForOtherFinancingActivities"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_c62c7c8a-d834-4b48-9d75-fda47df9868d" xlink:to="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_10970b84-e9b1-43ad-93f2-f8ccb0b98525" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_7810972e-0723-45ba-9579-3b5d07eccb05" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_11b01fb5-d326-47fe-a656-095469d2332d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_7810972e-0723-45ba-9579-3b5d07eccb05" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_11b01fb5-d326-47fe-a656-095469d2332d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_acbdb695-7004-48a4-8ab5-fe54db1d8dc8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_7810972e-0723-45ba-9579-3b5d07eccb05" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_acbdb695-7004-48a4-8ab5-fe54db1d8dc8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_f8cad5af-3eee-4d86-89bc-06ec809ae9bf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_7810972e-0723-45ba-9579-3b5d07eccb05" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_f8cad5af-3eee-4d86-89bc-06ec809ae9bf" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/EarningspershareDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#EarningspershareDetails"/>
  <link:calculationLink xlink:role="http://www.amgen.com/role/EarningspershareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_98612c4a-2bc6-4d86-ae0f-6f58d558681c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_21a54a1e-d9af-4190-a29a-400e13da25c1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_98612c4a-2bc6-4d86-ae0f-6f58d558681c" xlink:to="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_21a54a1e-d9af-4190-a29a-400e13da25c1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_445539a7-9db4-4c30-98d5-bef0abaf4d03" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_98612c4a-2bc6-4d86-ae0f-6f58d558681c" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_445539a7-9db4-4c30-98d5-bef0abaf4d03" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InvestmentsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#InvestmentsDetails"/>
  <link:calculationLink xlink:role="http://www.amgen.com/role/InvestmentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_84acaf4c-ffed-4197-a6c4-f796f1213e48" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_6a83b566-5c14-4c47-b982-7a0230f1f820" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_84acaf4c-ffed-4197-a6c4-f796f1213e48" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_6a83b566-5c14-4c47-b982-7a0230f1f820" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_6899cd17-cfbe-4e2b-a677-bc6942e446ff" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_84acaf4c-ffed-4197-a6c4-f796f1213e48" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_6899cd17-cfbe-4e2b-a677-bc6942e446ff" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_04917f59-9e56-4d4c-a7da-cab9be16089c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_84acaf4c-ffed-4197-a6c4-f796f1213e48" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_04917f59-9e56-4d4c-a7da-cab9be16089c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#InvestmentsFairValuesbyClassificationDetails"/>
  <link:calculationLink xlink:role="http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_37c19d95-67d2-407c-a275-a91f88014b02" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_94ad40dc-d5f4-4e7c-a88e-20fd4c313258" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_37c19d95-67d2-407c-a275-a91f88014b02" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_94ad40dc-d5f4-4e7c-a88e-20fd4c313258" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_f2a4050c-c600-4f2d-a851-44214ffcb206" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_37c19d95-67d2-407c-a275-a91f88014b02" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_f2a4050c-c600-4f2d-a851-44214ffcb206" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#InvestmentsFairValuesbyContractualMaturityDetails"/>
  <link:calculationLink xlink:role="http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_4432bba0-84ca-4640-b3ed-ce68b960c3f1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_4e00c022-d293-41ef-9774-b0accb41ce7b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_4432bba0-84ca-4640-b3ed-ce68b960c3f1" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_4e00c022-d293-41ef-9774-b0accb41ce7b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue_b32b6be3-d90c-4cb5-8a44-c9e3399d648a" xlink:href="amgn-20210930.xsd#amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_4432bba0-84ca-4640-b3ed-ce68b960c3f1" xlink:to="loc_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue_b32b6be3-d90c-4cb5-8a44-c9e3399d648a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue_d5be183c-9ef9-463d-8e4b-9547bb16e257" xlink:href="amgn-20210930.xsd#amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_4432bba0-84ca-4640-b3ed-ce68b960c3f1" xlink:to="loc_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue_d5be183c-9ef9-463d-8e4b-9547bb16e257" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_51c2e53f-8b7e-48d4-afda-dc33aaa00612" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_4432bba0-84ca-4640-b3ed-ce68b960c3f1" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_51c2e53f-8b7e-48d4-afda-dc33aaa00612" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InventoriesDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#InventoriesDetails"/>
  <link:calculationLink xlink:role="http://www.amgen.com/role/InventoriesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_5c0c8f12-ff74-4ff1-9f89-66dfe4b1f042" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryRawMaterialsNetOfReserves_3d94ab07-c5bf-415d-b094-4cfa14524c4a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryRawMaterialsNetOfReserves"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryNet_5c0c8f12-ff74-4ff1-9f89-66dfe4b1f042" xlink:to="loc_us-gaap_InventoryRawMaterialsNetOfReserves_3d94ab07-c5bf-415d-b094-4cfa14524c4a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryWorkInProcessNetOfReserves_412fb0b9-c17a-4443-809b-f2890174a62e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryWorkInProcessNetOfReserves"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryNet_5c0c8f12-ff74-4ff1-9f89-66dfe4b1f042" xlink:to="loc_us-gaap_InventoryWorkInProcessNetOfReserves_412fb0b9-c17a-4443-809b-f2890174a62e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_7c4b93fa-eaaa-4826-a0c9-92ad0b5dd20d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryFinishedGoodsNetOfReserves"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryNet_5c0c8f12-ff74-4ff1-9f89-66dfe4b1f042" xlink:to="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_7c4b93fa-eaaa-4826-a0c9-92ad0b5dd20d" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"/>
  <link:calculationLink xlink:role="http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_92e4d4d2-8a4c-44f5-bdd5-d32cfae5359b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_11464b05-4d6d-4b15-95b5-54e69435b9ad" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_92e4d4d2-8a4c-44f5-bdd5-d32cfae5359b" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_11464b05-4d6d-4b15-95b5-54e69435b9ad" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_01ec619f-7143-4118-9434-1360a01eca3a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_92e4d4d2-8a4c-44f5-bdd5-d32cfae5359b" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_01ec619f-7143-4118-9434-1360a01eca3a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_6a14d06a-4c0a-4030-8b11-443250328818" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_IdentifiableIntangibleAssetsGross_6861934b-df15-4be6-8a83-86a499ada31e" xlink:href="amgn-20210930.xsd#amgn_IdentifiableIntangibleAssetsGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_6a14d06a-4c0a-4030-8b11-443250328818" xlink:to="loc_amgn_IdentifiableIntangibleAssetsGross_6861934b-df15-4be6-8a83-86a499ada31e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization_0564eca6-f18e-4354-b7c1-0c3b32b79dbd" xlink:href="amgn-20210930.xsd#amgn_IdentifiableIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_6a14d06a-4c0a-4030-8b11-443250328818" xlink:to="loc_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization_0564eca6-f18e-4354-b7c1-0c3b32b79dbd" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"/>
  <link:calculationLink xlink:role="http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_87b5e449-fb92-4461-a851-95aa289a7924" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebt"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_eed13eb8-0def-458a-bc1c-3309ab68943e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_87b5e449-fb92-4461-a851-95aa289a7924" xlink:to="loc_us-gaap_LongTermDebtCurrent_eed13eb8-0def-458a-bc1c-3309ab68943e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_2b277326-f40f-42cc-9384-dc21a6c441eb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_87b5e449-fb92-4461-a851-95aa289a7924" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_2b277326-f40f-42cc-9384-dc21a6c441eb" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/FairvaluemeasurementDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#FairvaluemeasurementDetails"/>
  <link:calculationLink xlink:role="http://www.amgen.com/role/FairvaluemeasurementDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_72042dc2-014c-49af-9af1-7aa5d7028331" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_00183e21-fb19-4f84-8bc6-3e00f0ee3b68" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_72042dc2-014c-49af-9af1-7aa5d7028331" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_00183e21-fb19-4f84-8bc6-3e00f0ee3b68" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNi_8ae4a747-3289-4e12-9073-36e51630f20d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesFvNi"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_72042dc2-014c-49af-9af1-7aa5d7028331" xlink:to="loc_us-gaap_EquitySecuritiesFvNi_8ae4a747-3289-4e12-9073-36e51630f20d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure_58b8128e-6963-4612-9c0c-98160f52e2d0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignCurrencyContractAssetFairValueDisclosure"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_72042dc2-014c-49af-9af1-7aa5d7028331" xlink:to="loc_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure_58b8128e-6963-4612-9c0c-98160f52e2d0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateFairValueHedgeAssetAtFairValue_3aa4e5ff-dc0a-4808-b2ed-bb77d52b6d77" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateFairValueHedgeAssetAtFairValue"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_72042dc2-014c-49af-9af1-7aa5d7028331" xlink:to="loc_us-gaap_InterestRateFairValueHedgeAssetAtFairValue_3aa4e5ff-dc0a-4808-b2ed-bb77d52b6d77" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_28cacc7a-630b-4a23-a2d2-d7c15bf8b983" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_f99f98ee-fcb9-4a28-a169-7b6d9fb29746" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_28cacc7a-630b-4a23-a2d2-d7c15bf8b983" xlink:to="loc_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_f99f98ee-fcb9-4a28-a169-7b6d9fb29746" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_96cec922-1812-4a1a-869e-113407bcb374" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_28cacc7a-630b-4a23-a2d2-d7c15bf8b983" xlink:to="loc_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_96cec922-1812-4a1a-869e-113407bcb374" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_6704ad2e-b77c-4167-87af-84a5aaa95fc0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_28cacc7a-630b-4a23-a2d2-d7c15bf8b983" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_6704ad2e-b77c-4167-87af-84a5aaa95fc0" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.DEF
<SEQUENCE>7
<FILENAME>amgn-20210930_def.xml
<DESCRIPTION>XBRL TAXONOMY EXTENSION DEFINITION LINKBASE DOCUMENT
<TEXT>
<XBRL>
<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2021 Workiva-->
<!--r:e5235af6-2e2c-44cc-b741-bc0b6d42fa8f,g:5c86b37c-c57f-4c71-acc2-468d6efa37c1-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/all" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#all"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#hypercube-dimension"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-default"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-domain"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/domain-member" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#domain-member"/>
  <link:roleRef roleURI="http://www.amgen.com/role/CoverPage" xlink:type="simple" xlink:href="amgn-20210930.xsd#CoverPage"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/CoverPage" xlink:type="extended" id="i5bba73944557406fb9db0f3ebaa49c5a_CoverPage">
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityInformationLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_d2b7d437-af72-4593-9a03-e3b1b89d68c6" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentType"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_DocumentType_d2b7d437-af72-4593-9a03-e3b1b89d68c6" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentQuarterlyReport_4fee6c6a-4076-437c-beed-27a9d33c2d5d" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentQuarterlyReport"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_DocumentQuarterlyReport_4fee6c6a-4076-437c-beed-27a9d33c2d5d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_bd278e5b-1973-45cc-a2c9-aa53746f98cf" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentPeriodEndDate"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_DocumentPeriodEndDate_bd278e5b-1973-45cc-a2c9-aa53746f98cf" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentTransitionReport_b679502b-098d-4c5f-80b5-262623c93d92" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentTransitionReport"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_DocumentTransitionReport_b679502b-098d-4c5f-80b5-262623c93d92" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_2ca92a42-6d56-4f29-9c7b-e924a575eeb2" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityFileNumber"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityFileNumber_2ca92a42-6d56-4f29-9c7b-e924a575eeb2" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_0a799626-c61f-45b8-8f2c-d27c711feffd" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityRegistrantName"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityRegistrantName_0a799626-c61f-45b8-8f2c-d27c711feffd" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_ff06d7ef-7303-4fe7-b8aa-fe1aba6410c0" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCentralIndexKey"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityCentralIndexKey_ff06d7ef-7303-4fe7-b8aa-fe1aba6410c0" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_eca216e4-fb32-48ce-b140-96c472870c27" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_AmendmentFlag"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_AmendmentFlag_eca216e4-fb32-48ce-b140-96c472870c27" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalYearFocus_b9373172-93cd-4023-abfe-15c063f3750b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentFiscalYearFocus"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_DocumentFiscalYearFocus_b9373172-93cd-4023-abfe-15c063f3750b" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalPeriodFocus_a6e44e17-b981-49b8-a181-48211da9e5e1" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentFiscalPeriodFocus"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_DocumentFiscalPeriodFocus_a6e44e17-b981-49b8-a181-48211da9e5e1" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CurrentFiscalYearEndDate_74833464-c03e-4081-8abb-9d3aba7c441f" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CurrentFiscalYearEndDate"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_CurrentFiscalYearEndDate_74833464-c03e-4081-8abb-9d3aba7c441f" xlink:type="arc" order="10"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_38672f86-f5c4-408b-a483-4538206f6266" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityIncorporationStateCountryCode_38672f86-f5c4-408b-a483-4538206f6266" xlink:type="arc" order="11"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_a63b595c-91bf-4c23-b237-5a0c78211aab" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityTaxIdentificationNumber_a63b595c-91bf-4c23-b237-5a0c78211aab" xlink:type="arc" order="12"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_36cd7e63-3c05-4c2b-a04d-6802f3eacc6b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressAddressLine1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityAddressAddressLine1_36cd7e63-3c05-4c2b-a04d-6802f3eacc6b" xlink:type="arc" order="13"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_1f5608b0-3b93-4e9e-999d-105e3c20322c" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressCityOrTown"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityAddressCityOrTown_1f5608b0-3b93-4e9e-999d-105e3c20322c" xlink:type="arc" order="14"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_6c88e06a-45a0-49da-a6b3-8264644bc58b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressStateOrProvince"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityAddressStateOrProvince_6c88e06a-45a0-49da-a6b3-8264644bc58b" xlink:type="arc" order="15"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_fae8f267-b2e7-4b6c-a1ce-6718e8ba488a" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressPostalZipCode"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityAddressPostalZipCode_fae8f267-b2e7-4b6c-a1ce-6718e8ba488a" xlink:type="arc" order="16"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_147e05b0-b86b-498e-945c-92f837ee4dee" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CityAreaCode"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_CityAreaCode_147e05b0-b86b-498e-945c-92f837ee4dee" xlink:type="arc" order="17"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_d28dd0c9-fd7c-4791-a5ec-176025eb7516" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_LocalPhoneNumber"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_LocalPhoneNumber_d28dd0c9-fd7c-4791-a5ec-176025eb7516" xlink:type="arc" order="18"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_2e921c9f-7da3-459a-ada0-353cfc4a3a85" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_Security12bTitle"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_Security12bTitle_2e921c9f-7da3-459a-ada0-353cfc4a3a85" xlink:type="arc" order="19"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_7dd4d5c4-455b-417a-87bd-b0034b48fd7c" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_TradingSymbol"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_TradingSymbol_7dd4d5c4-455b-417a-87bd-b0034b48fd7c" xlink:type="arc" order="20"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_357c417e-0ef4-4bcc-8b02-e26b97e787de" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_SecurityExchangeName"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_SecurityExchangeName_357c417e-0ef4-4bcc-8b02-e26b97e787de" xlink:type="arc" order="21"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCurrentReportingStatus_cf011862-01d1-4e5c-9b10-ea03a54e9641" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCurrentReportingStatus"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityCurrentReportingStatus_cf011862-01d1-4e5c-9b10-ea03a54e9641" xlink:type="arc" order="22"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInteractiveDataCurrent_14d33b15-38a6-4812-b355-911d79444830" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityInteractiveDataCurrent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityInteractiveDataCurrent_14d33b15-38a6-4812-b355-911d79444830" xlink:type="arc" order="23"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFilerCategory_63bfbf25-f81b-4a4f-9154-9a45d0ca41c1" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityFilerCategory"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityFilerCategory_63bfbf25-f81b-4a4f-9154-9a45d0ca41c1" xlink:type="arc" order="24"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntitySmallBusiness_d836a9ed-0878-4377-8675-61a0183d40bb" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntitySmallBusiness"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntitySmallBusiness_d836a9ed-0878-4377-8675-61a0183d40bb" xlink:type="arc" order="25"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_c0b137f5-d92a-486a-bebe-50c26ff5f80b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityEmergingGrowthCompany_c0b137f5-d92a-486a-bebe-50c26ff5f80b" xlink:type="arc" order="26"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityShellCompany_1b578911-d757-454e-977b-e7c58cf8cb0e" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityShellCompany"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityShellCompany_1b578911-d757-454e-977b-e7c58cf8cb0e" xlink:type="arc" order="27"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_fc252067-055b-4b22-90f0-bbfa79e8843f" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCommonStockSharesOutstanding"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_fc252067-055b-4b22-90f0-bbfa79e8843f" xlink:type="arc" order="28"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntitiesTable_01b57b85-be53-43d0-975c-30963e42dd18" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntitiesTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntitiesTable_01b57b85-be53-43d0-975c-30963e42dd18" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityListingsExchangeAxis_d1c213f4-9da7-4285-8718-54c9983da559" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityListingsExchangeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_dei_EntitiesTable_01b57b85-be53-43d0-975c-30963e42dd18" xlink:to="loc_dei_EntityListingsExchangeAxis_d1c213f4-9da7-4285-8718-54c9983da559" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_ExchangeDomain_d1c213f4-9da7-4285-8718-54c9983da559_default" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_ExchangeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_dei_EntityListingsExchangeAxis_d1c213f4-9da7-4285-8718-54c9983da559" xlink:to="loc_dei_ExchangeDomain_d1c213f4-9da7-4285-8718-54c9983da559_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_ExchangeDomain_256f6c3f-dbe1-4db2-add8-e76890adaf7b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_ExchangeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_dei_EntityListingsExchangeAxis_d1c213f4-9da7-4285-8718-54c9983da559" xlink:to="loc_dei_ExchangeDomain_256f6c3f-dbe1-4db2-add8-e76890adaf7b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_exch_XNGS_413afd56-e23a-469d-82c1-c9a5303a7998" xlink:href="https://xbrl.sec.gov/exch/2021/exch-2021.xsd#exch_XNGS"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_ExchangeDomain_256f6c3f-dbe1-4db2-add8-e76890adaf7b" xlink:to="loc_exch_XNGS_413afd56-e23a-469d-82c1-c9a5303a7998" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_2661aba9-85d4-4d0f-9ac1-04dc6daf1fc5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_dei_EntitiesTable_01b57b85-be53-43d0-975c-30963e42dd18" xlink:to="loc_us-gaap_StatementClassOfStockAxis_2661aba9-85d4-4d0f-9ac1-04dc6daf1fc5" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_2661aba9-85d4-4d0f-9ac1-04dc6daf1fc5_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfStockDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementClassOfStockAxis_2661aba9-85d4-4d0f-9ac1-04dc6daf1fc5" xlink:to="loc_us-gaap_ClassOfStockDomain_2661aba9-85d4-4d0f-9ac1-04dc6daf1fc5_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_fd4c96f4-deb0-483b-a1a1-8d0c12c50571" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfStockDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementClassOfStockAxis_2661aba9-85d4-4d0f-9ac1-04dc6daf1fc5" xlink:to="loc_us-gaap_ClassOfStockDomain_fd4c96f4-deb0-483b-a1a1-8d0c12c50571" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_6e491290-cf54-4f63-8ac6-3eebcdb3efb8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockDomain_fd4c96f4-deb0-483b-a1a1-8d0c12c50571" xlink:to="loc_us-gaap_CommonStockMember_6e491290-cf54-4f63-8ac6-3eebcdb3efb8" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_A1.250SeniorNotesDue2022Member_358d3b33-f5fc-40cf-8078-6b3815eabfb8" xlink:href="amgn-20210930.xsd#amgn_A1.250SeniorNotesDue2022Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockDomain_fd4c96f4-deb0-483b-a1a1-8d0c12c50571" xlink:to="loc_amgn_A1.250SeniorNotesDue2022Member_358d3b33-f5fc-40cf-8078-6b3815eabfb8" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_A2.00SeniorNotesDue2026Member_843ade05-721b-4a72-8822-e0660c02f527" xlink:href="amgn-20210930.xsd#amgn_A2.00SeniorNotesDue2026Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockDomain_fd4c96f4-deb0-483b-a1a1-8d0c12c50571" xlink:to="loc_amgn_A2.00SeniorNotesDue2026Member_843ade05-721b-4a72-8822-e0660c02f527" xlink:type="arc" order="2"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome" xlink:type="simple" xlink:href="amgn-20210930.xsd#CondensedConsolidatedStatementsofIncome"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome" xlink:type="extended" id="i7e1d5486388f41c6b0a4235ed8ff98d7_CondensedConsolidatedStatementsofIncome">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenuesAbstract_3a19ba09-1350-4960-b8a8-fe897be03157" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenuesAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_RevenuesAbstract_3a19ba09-1350-4960-b8a8-fe897be03157" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_09614b7d-3865-4a28-a33f-c5d9c7669e8d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RevenuesAbstract_3a19ba09-1350-4960-b8a8-fe897be03157" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_09614b7d-3865-4a28-a33f-c5d9c7669e8d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostsAndExpensesAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_15ee6ec4-0517-40fd-978e-aad6e0506b65" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_15ee6ec4-0517-40fd-978e-aad6e0506b65" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost_341563d2-0b0a-4635-b41b-c1f6c6898d41" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost_341563d2-0b0a-4635-b41b-c1f6c6898d41" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_80886054-d94a-4bb0-88a2-1541658c9de4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:to="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_80886054-d94a-4bb0-88a2-1541658c9de4" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_e6e9f977-73cf-43f7-9ac2-48d4a5a88e7a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_e6e9f977-73cf-43f7-9ac2-48d4a5a88e7a" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherGeneralExpense_a8888703-036c-474f-8384-68903ef92599" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherGeneralExpense"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:to="loc_us-gaap_OtherGeneralExpense_a8888703-036c-474f-8384-68903ef92599" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses_e10bfffc-4ea6-453f-8feb-611e8d609fa1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostsAndExpenses"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:to="loc_us-gaap_CostsAndExpenses_e10bfffc-4ea6-453f-8feb-611e8d609fa1" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_ff02d73b-79fa-4754-bcc0-515d23e118ec" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_OperatingIncomeLoss_ff02d73b-79fa-4754-bcc0-515d23e118ec" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebt_85770760-d55d-4a99-bb3d-33a224bcfcdb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestExpenseDebt"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_InterestExpenseDebt_85770760-d55d-4a99-bb3d-33a224bcfcdb" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_5eb92c64-97a2-48f5-a761-f16df3afe102" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NonoperatingIncomeExpense"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_5eb92c64-97a2-48f5-a761-f16df3afe102" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_ac55f0b9-10fa-41e1-8d63-a01d85b1d529" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_ac55f0b9-10fa-41e1-8d63-a01d85b1d529" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_3b47bf84-a8d8-4b5d-8cdc-8d77b2c8b323" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_3b47bf84-a8d8-4b5d-8cdc-8d77b2c8b323" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_b9a6eb70-7c94-44e8-a09e-43c6eccbacfd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_NetIncomeLoss_b9a6eb70-7c94-44e8-a09e-43c6eccbacfd" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_72e69f9d-cb40-4fae-a26f-43e040553bf9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_EarningsPerShareAbstract_72e69f9d-cb40-4fae-a26f-43e040553bf9" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_9225ee63-dc9d-4611-8efe-ff108fa1b3b5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareBasic"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EarningsPerShareAbstract_72e69f9d-cb40-4fae-a26f-43e040553bf9" xlink:to="loc_us-gaap_EarningsPerShareBasic_9225ee63-dc9d-4611-8efe-ff108fa1b3b5" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_4059413e-4cfd-4973-92ea-17778cf5989e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareDiluted"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EarningsPerShareAbstract_72e69f9d-cb40-4fae-a26f-43e040553bf9" xlink:to="loc_us-gaap_EarningsPerShareDiluted_4059413e-4cfd-4973-92ea-17778cf5989e" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_de7f44b4-6475-4ad1-872d-1b53fade021a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_de7f44b4-6475-4ad1-872d-1b53fade021a" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_6af2a997-de41-401d-b068-b67e574d8e97" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_de7f44b4-6475-4ad1-872d-1b53fade021a" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_6af2a997-de41-401d-b068-b67e574d8e97" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_af7ab5aa-7367-4262-a05b-85e1f6ca23df" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_de7f44b4-6475-4ad1-872d-1b53fade021a" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_af7ab5aa-7367-4262-a05b-85e1f6ca23df" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_b2bffd96-2f75-4386-a786-fb5fd3508977" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_StatementTable_b2bffd96-2f75-4386-a786-fb5fd3508977" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_5d2336af-11bb-4f80-96d5-ce6cd02c97c4" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductOrServiceAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_StatementTable_b2bffd96-2f75-4386-a786-fb5fd3508977" xlink:to="loc_srt_ProductOrServiceAxis_5d2336af-11bb-4f80-96d5-ce6cd02c97c4" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_5d2336af-11bb-4f80-96d5-ce6cd02c97c4_default" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ProductOrServiceAxis_5d2336af-11bb-4f80-96d5-ce6cd02c97c4" xlink:to="loc_srt_ProductsAndServicesDomain_5d2336af-11bb-4f80-96d5-ce6cd02c97c4_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_24c59671-596b-47a3-b917-a354cd837113" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ProductOrServiceAxis_5d2336af-11bb-4f80-96d5-ce6cd02c97c4" xlink:to="loc_srt_ProductsAndServicesDomain_24c59671-596b-47a3-b917-a354cd837113" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_e3e889f1-ecd3-4059-acbd-4e19ad6f039d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_24c59671-596b-47a3-b917-a354cd837113" xlink:to="loc_us-gaap_ProductMember_e3e889f1-ecd3-4059-acbd-4e19ad6f039d" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductAndServiceOtherMember_feded7b8-df39-487a-bebc-ff0b8396f1ab" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductAndServiceOtherMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_24c59671-596b-47a3-b917-a354cd837113" xlink:to="loc_us-gaap_ProductAndServiceOtherMember_feded7b8-df39-487a-bebc-ff0b8396f1ab" xlink:type="arc" order="1"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity" xlink:type="simple" xlink:href="amgn-20210930.xsd#CondensedConsolidatedStatementsofStockholdersEquity"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity" xlink:type="extended" id="i68b1c1abaa6b4baf8769fe31a2bc8f04_CondensedConsolidatedStatementsofStockholdersEquity">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_5f94fa09-2283-41f1-a42d-0e3657288b82" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_5f94fa09-2283-41f1-a42d-0e3657288b82" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_ca1a7796-50c9-4813-baef-44adba643da3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_ca1a7796-50c9-4813-baef-44adba643da3" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_7d0ef42e-40b2-4fe6-9406-d0c13bfa53d9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_StockholdersEquity_7d0ef42e-40b2-4fe6-9406-d0c13bfa53d9" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_de95967f-886f-44f3-a122-d89570687679" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_NetIncomeLoss_de95967f-886f-44f3-a122-d89570687679" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_65f2b100-ff0e-48ad-80ac-c5ff205b7ee2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_65f2b100-ff0e-48ad-80ac-c5ff205b7ee2" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DividendsCommonStockCash_ecd78bc3-5f33-43e8-8eb5-e013661a7214" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DividendsCommonStockCash"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_DividendsCommonStockCash_ecd78bc3-5f33-43e8-8eb5-e013661a7214" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_93ea35ef-164b-458d-9a59-b3e6f7fd8357" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_93ea35ef-164b-458d-9a59-b3e6f7fd8357" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_7f2dd661-abc3-47b3-8381-6d5d9f42d1a4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_7f2dd661-abc3-47b3-8381-6d5d9f42d1a4" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_02d9c41e-ecfa-41df-b5eb-9edac59345c8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_02d9c41e-ecfa-41df-b5eb-9edac59345c8" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet_92478de4-37a5-440a-8503-883690b3ed14" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet_92478de4-37a5-440a-8503-883690b3ed14" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares_87cfe528-8915-4f44-9089-7ccc31a77113" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchasedAndRetiredDuringPeriodShares"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares_87cfe528-8915-4f44-9089-7ccc31a77113" xlink:type="arc" order="10"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue_845a955f-f7e3-457e-8bf1-5af290c4d245" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchasedAndRetiredDuringPeriodValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue_845a955f-f7e3-457e-8bf1-5af290c4d245" xlink:type="arc" order="11"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityOther_930e64a8-d828-458c-8d21-8901a29b9b9b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquityOther"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_StockholdersEquityOther_930e64a8-d828-458c-8d21-8901a29b9b9b" xlink:type="arc" order="12"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_eacb84a7-ada4-4b0d-ba68-27ccefb4224e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_ee56688e-773f-45f7-8486-2cd7fbfb1651" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_33eac8b5-949e-4ba3-96af-c0e2c192568b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_StatementLineItems_5f94fa09-2283-41f1-a42d-0e3657288b82" xlink:to="loc_us-gaap_StatementTable_33eac8b5-949e-4ba3-96af-c0e2c192568b" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_5eb507c1-aa0f-4f27-b0df-466e4860d39a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_StatementTable_33eac8b5-949e-4ba3-96af-c0e2c192568b" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_5eb507c1-aa0f-4f27-b0df-466e4860d39a" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_5eb507c1-aa0f-4f27-b0df-466e4860d39a_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_5eb507c1-aa0f-4f27-b0df-466e4860d39a" xlink:to="loc_us-gaap_EquityComponentDomain_5eb507c1-aa0f-4f27-b0df-466e4860d39a_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_599f2207-121e-4a67-91af-411e6783e81f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_5eb507c1-aa0f-4f27-b0df-466e4860d39a" xlink:to="loc_us-gaap_EquityComponentDomain_599f2207-121e-4a67-91af-411e6783e81f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_5a6945df-cac4-4ad1-9749-3d66cd104a62" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_599f2207-121e-4a67-91af-411e6783e81f" xlink:to="loc_us-gaap_CommonStockMember_5a6945df-cac4-4ad1-9749-3d66cd104a62" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember_ae6946da-dc5e-42c2-90f7-13282e5bc168" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_599f2207-121e-4a67-91af-411e6783e81f" xlink:to="loc_us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember_ae6946da-dc5e-42c2-90f7-13282e5bc168" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_b17d60d5-54e6-4e6f-8276-582774d38207" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_599f2207-121e-4a67-91af-411e6783e81f" xlink:to="loc_us-gaap_RetainedEarningsMember_b17d60d5-54e6-4e6f-8276-582774d38207" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_ff0047c2-cd55-49cb-aa0f-95e9e6da8334" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_599f2207-121e-4a67-91af-411e6783e81f" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_ff0047c2-cd55-49cb-aa0f-95e9e6da8334" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_aec6d8be-38bc-40fe-9f8f-95d5a5090400" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_StatementTable_33eac8b5-949e-4ba3-96af-c0e2c192568b" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_aec6d8be-38bc-40fe-9f8f-95d5a5090400" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_aec6d8be-38bc-40fe-9f8f-95d5a5090400_default" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_aec6d8be-38bc-40fe-9f8f-95d5a5090400" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_aec6d8be-38bc-40fe-9f8f-95d5a5090400_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_03180f8f-adb3-40fa-9c55-2cc3b71072e7" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_aec6d8be-38bc-40fe-9f8f-95d5a5090400" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_03180f8f-adb3-40fa-9c55-2cc3b71072e7" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_dfe4ea6b-29ce-4512-b6ca-5e74102d04ed" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_03180f8f-adb3-40fa-9c55-2cc3b71072e7" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_dfe4ea6b-29ce-4512-b6ca-5e74102d04ed" xlink:type="arc" order="0"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#BusinessCombinationsandAssetAcquisitionsDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails" xlink:type="extended" id="i1ef6d8c73c324cee9fd35d69315802e3_BusinessCombinationsandAssetAcquisitionsDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_1ab7a436-11d2-4dd4-ab88-3677ef9bceed" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_27fd380e-1b29-4256-8b7e-a2405d4242c3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_1ab7a436-11d2-4dd4-ab88-3677ef9bceed" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_27fd380e-1b29-4256-8b7e-a2405d4242c3" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_2189d45e-963d-43ef-9889-3ca193942673" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_1ab7a436-11d2-4dd4-ab88-3677ef9bceed" xlink:to="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_2189d45e-963d-43ef-9889-3ca193942673" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_03bc988b-22df-404c-8608-050ad7319149" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_1ab7a436-11d2-4dd4-ab88-3677ef9bceed" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_03bc988b-22df-404c-8608-050ad7319149" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther_39dc343d-80a6-4ee1-95e8-761040c4cfe9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_1ab7a436-11d2-4dd4-ab88-3677ef9bceed" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther_39dc343d-80a6-4ee1-95e8-761040c4cfe9" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets_4a47bd92-3d07-4275-a796-f4e0cd8ca847" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_1ab7a436-11d2-4dd4-ab88-3677ef9bceed" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets_4a47bd92-3d07-4275-a796-f4e0cd8ca847" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_9a8b9cf6-68f4-411d-b8ab-2bb0a2e769b3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_1ab7a436-11d2-4dd4-ab88-3677ef9bceed" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_9a8b9cf6-68f4-411d-b8ab-2bb0a2e769b3" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_0d307722-28ae-4d64-862a-a557efa092e8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_9a8b9cf6-68f4-411d-b8ab-2bb0a2e769b3" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_0d307722-28ae-4d64-862a-a557efa092e8" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0d307722-28ae-4d64-862a-a557efa092e8_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_0d307722-28ae-4d64-862a-a557efa092e8" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0d307722-28ae-4d64-862a-a557efa092e8_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_20ec96fc-24a0-4c45-a97d-0d13c2aba933" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_0d307722-28ae-4d64-862a-a557efa092e8" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_20ec96fc-24a0-4c45-a97d-0d13c2aba933" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePrimeTherapeuticsIncMember_eb6c0986-eedc-4add-915d-a5a7a6d1b8bf" xlink:href="amgn-20210930.xsd#amgn_FivePrimeTherapeuticsIncMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_20ec96fc-24a0-4c45-a97d-0d13c2aba933" xlink:to="loc_amgn_FivePrimeTherapeuticsIncMember_eb6c0986-eedc-4add-915d-a5a7a6d1b8bf" xlink:type="arc" order="0"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/RevenuesDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#RevenuesDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/RevenuesDetails" xlink:type="extended" id="i590e8aada913475bbb7284f16522ff53_RevenuesDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_8ca69801-dd5e-4c6e-8711-960314cecaf5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_1aeefe0d-865a-49fc-b8f7-dc72da691917" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_8ca69801-dd5e-4c6e-8711-960314cecaf5" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_1aeefe0d-865a-49fc-b8f7-dc72da691917" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_8574438d-da32-4e24-8b1c-5d6d2d194fd3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_8ca69801-dd5e-4c6e-8711-960314cecaf5" xlink:to="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_8574438d-da32-4e24-8b1c-5d6d2d194fd3" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_7ff770ea-5844-4160-be1c-12004dc2e0d3" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductOrServiceAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_8574438d-da32-4e24-8b1c-5d6d2d194fd3" xlink:to="loc_srt_ProductOrServiceAxis_7ff770ea-5844-4160-be1c-12004dc2e0d3" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_7ff770ea-5844-4160-be1c-12004dc2e0d3_default" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ProductOrServiceAxis_7ff770ea-5844-4160-be1c-12004dc2e0d3" xlink:to="loc_srt_ProductsAndServicesDomain_7ff770ea-5844-4160-be1c-12004dc2e0d3_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_3066e3a3-9386-41ce-9968-89c12f4a74f0" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ProductOrServiceAxis_7ff770ea-5844-4160-be1c-12004dc2e0d3" xlink:to="loc_srt_ProductsAndServicesDomain_3066e3a3-9386-41ce-9968-89c12f4a74f0" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_3066e3a3-9386-41ce-9968-89c12f4a74f0" xlink:to="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_EnbrelMember_ba4cf9ae-af4a-4223-aa7a-27c323edd987" xlink:href="amgn-20210930.xsd#amgn_EnbrelMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_EnbrelMember_ba4cf9ae-af4a-4223-aa7a-27c323edd987" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ProliaMember_de6d8fbb-e16a-4382-b1ad-29f7f844f687" xlink:href="amgn-20210930.xsd#amgn_ProliaMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_ProliaMember_de6d8fbb-e16a-4382-b1ad-29f7f844f687" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtezlaMember_b8632ce9-0c96-49f5-8e8c-a3b2da534332" xlink:href="amgn-20210930.xsd#amgn_OtezlaMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_OtezlaMember_b8632ce9-0c96-49f5-8e8c-a3b2da534332" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_XgevaMember_0d6c22e9-c9be-4b35-9668-d01fe93f7252" xlink:href="amgn-20210930.xsd#amgn_XgevaMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_XgevaMember_0d6c22e9-c9be-4b35-9668-d01fe93f7252" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_NeulastaMember_de8e75ce-2db9-450d-a4a5-2d9739c7ac74" xlink:href="amgn-20210930.xsd#amgn_NeulastaMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_NeulastaMember_de8e75ce-2db9-450d-a4a5-2d9739c7ac74" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AranespMember_467ffdef-5554-4e10-b9ef-2093e2655b21" xlink:href="amgn-20210930.xsd#amgn_AranespMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_AranespMember_467ffdef-5554-4e10-b9ef-2093e2655b21" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_RepathaevolocumabMember_3e650132-cfe6-4b01-82a3-66699840e7d9" xlink:href="amgn-20210930.xsd#amgn_RepathaevolocumabMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_RepathaevolocumabMember_3e650132-cfe6-4b01-82a3-66699840e7d9" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_KyprolisMember_db9bf625-8a42-49f9-811b-cefe4ba16795" xlink:href="amgn-20210930.xsd#amgn_KyprolisMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_KyprolisMember_db9bf625-8a42-49f9-811b-cefe4ba16795" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherProductsMember_44b9bd68-a5e6-446a-82a1-64cbcd32408b" xlink:href="amgn-20210930.xsd#amgn_OtherProductsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_OtherProductsMember_44b9bd68-a5e6-446a-82a1-64cbcd32408b" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductAndServiceOtherMember_f512d27c-d3f1-4f61-ba4d-19e0f81598bd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductAndServiceOtherMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_3066e3a3-9386-41ce-9968-89c12f4a74f0" xlink:to="loc_us-gaap_ProductAndServiceOtherMember_f512d27c-d3f1-4f61-ba4d-19e0f81598bd" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementGeographicalAxis_2a55b762-cd04-4f07-9553-b1809e63aba9" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_StatementGeographicalAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_8574438d-da32-4e24-8b1c-5d6d2d194fd3" xlink:to="loc_srt_StatementGeographicalAxis_2a55b762-cd04-4f07-9553-b1809e63aba9" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain_2a55b762-cd04-4f07-9553-b1809e63aba9_default" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_SegmentGeographicalDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_StatementGeographicalAxis_2a55b762-cd04-4f07-9553-b1809e63aba9" xlink:to="loc_srt_SegmentGeographicalDomain_2a55b762-cd04-4f07-9553-b1809e63aba9_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain_0ecd1e14-ad14-41af-922b-f928d89d28ad" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_SegmentGeographicalDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_StatementGeographicalAxis_2a55b762-cd04-4f07-9553-b1809e63aba9" xlink:to="loc_srt_SegmentGeographicalDomain_0ecd1e14-ad14-41af-922b-f928d89d28ad" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_country_US_ed6f850f-5e2a-4882-8b45-dec637cc0ac5" xlink:href="https://xbrl.sec.gov/country/2021/country-2021.xsd#country_US"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_SegmentGeographicalDomain_0ecd1e14-ad14-41af-922b-f928d89d28ad" xlink:to="loc_country_US_ed6f850f-5e2a-4882-8b45-dec637cc0ac5" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonUsMember_4c57f565-3125-440a-bfc5-e5af24bb4e72" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NonUsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_SegmentGeographicalDomain_0ecd1e14-ad14-41af-922b-f928d89d28ad" xlink:to="loc_us-gaap_NonUsMember_4c57f565-3125-440a-bfc5-e5af24bb4e72" xlink:type="arc" order="1"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/CollaborationsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#CollaborationsDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/CollaborationsDetails" xlink:type="extended" id="i44492e5840794111b84807c7cb898fa6_CollaborationsDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_0ba56a67-4757-43ba-8a2b-01a446c12102" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross_cc5e5a81-70bd-4006-ad55-83ebc3af4489" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_0ba56a67-4757-43ba-8a2b-01a446c12102" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross_cc5e5a81-70bd-4006-ad55-83ebc3af4489" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RecoveryOfDirectCosts_082d0e2e-8b7e-4f8d-aea4-f7868129210f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RecoveryOfDirectCosts"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_0ba56a67-4757-43ba-8a2b-01a446c12102" xlink:to="loc_us-gaap_RecoveryOfDirectCosts_082d0e2e-8b7e-4f8d-aea4-f7868129210f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_RecoveryOfDirectCostsReceivable_4602e225-3ff5-4552-838b-534ff9797059" xlink:href="amgn-20210930.xsd#amgn_RecoveryOfDirectCostsReceivable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_0ba56a67-4757-43ba-8a2b-01a446c12102" xlink:to="loc_amgn_RecoveryOfDirectCostsReceivable_4602e225-3ff5-4552-838b-534ff9797059" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_UpFrontPayment_383648c8-41d3-4bbe-81bb-82d9242451e5" xlink:href="amgn-20210930.xsd#amgn_UpFrontPayment"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_0ba56a67-4757-43ba-8a2b-01a446c12102" xlink:to="loc_amgn_UpFrontPayment_383648c8-41d3-4bbe-81bb-82d9242451e5" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments_9897dfc2-e55f-49ea-95b5-12ba2d222902" xlink:href="amgn-20210930.xsd#amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_0ba56a67-4757-43ba-8a2b-01a446c12102" xlink:to="loc_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments_9897dfc2-e55f-49ea-95b5-12ba2d222902" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_da5e15af-cca0-45aa-a28f-522a1deed315" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_0ba56a67-4757-43ba-8a2b-01a446c12102" xlink:to="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_da5e15af-cca0-45aa-a28f-522a1deed315" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfArrangementAxis_3ce18461-9a24-4202-9928-d6a044033551" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TypeOfArrangementAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_da5e15af-cca0-45aa-a28f-522a1deed315" xlink:to="loc_us-gaap_TypeOfArrangementAxis_3ce18461-9a24-4202-9928-d6a044033551" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_3ce18461-9a24-4202-9928-d6a044033551_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_TypeOfArrangementAxis_3ce18461-9a24-4202-9928-d6a044033551" xlink:to="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_3ce18461-9a24-4202-9928-d6a044033551_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_12b2dbe6-958b-46d3-95c4-a7852d1bfcca" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_TypeOfArrangementAxis_3ce18461-9a24-4202-9928-d6a044033551" xlink:to="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_12b2dbe6-958b-46d3-95c4-a7852d1bfcca" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_BeiGeneMember_2bd2f05a-86aa-4bc0-9a6c-e031b579b9e9" xlink:href="amgn-20210930.xsd#amgn_BeiGeneMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_12b2dbe6-958b-46d3-95c4-a7852d1bfcca" xlink:to="loc_amgn_BeiGeneMember_2bd2f05a-86aa-4bc0-9a6c-e031b579b9e9" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_KyowaKirinCoLtdMember_e0c1fead-8a43-4b34-b3cd-0ed613e6db1d" xlink:href="amgn-20210930.xsd#amgn_KyowaKirinCoLtdMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_12b2dbe6-958b-46d3-95c4-a7852d1bfcca" xlink:to="loc_amgn_KyowaKirinCoLtdMember_e0c1fead-8a43-4b34-b3cd-0ed613e6db1d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_180d4380-7518-42a7-b5c2-41dc23702468" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_da5e15af-cca0-45aa-a28f-522a1deed315" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_180d4380-7518-42a7-b5c2-41dc23702468" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_180d4380-7518-42a7-b5c2-41dc23702468_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_180d4380-7518-42a7-b5c2-41dc23702468" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_180d4380-7518-42a7-b5c2-41dc23702468_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_95959d1b-c25a-4d7a-b187-5a7c6123044a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_180d4380-7518-42a7-b5c2-41dc23702468" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_95959d1b-c25a-4d7a-b187-5a7c6123044a" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_e7500688-85f7-4736-ac25-63660a940626" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_95959d1b-c25a-4d7a-b187-5a7c6123044a" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_e7500688-85f7-4736-ac25-63660a940626" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_cf9f7420-346f-4810-a87d-9742d9508fee" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BalanceSheetLocationAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_da5e15af-cca0-45aa-a28f-522a1deed315" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_cf9f7420-346f-4810-a87d-9742d9508fee" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_cf9f7420-346f-4810-a87d-9742d9508fee_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BalanceSheetLocationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_cf9f7420-346f-4810-a87d-9742d9508fee" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_cf9f7420-346f-4810-a87d-9742d9508fee_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_002ac029-3bb7-40a6-a3a2-cbb3ff53b9de" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BalanceSheetLocationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_cf9f7420-346f-4810-a87d-9742d9508fee" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_002ac029-3bb7-40a6-a3a2-cbb3ff53b9de" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCurrentAssetsMember_d14e9d37-cc5d-4559-b562-0ab1823751c5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherCurrentAssetsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_002ac029-3bb7-40a6-a3a2-cbb3ff53b9de" xlink:to="loc_us-gaap_OtherCurrentAssetsMember_d14e9d37-cc5d-4559-b562-0ab1823751c5" xlink:type="arc" order="0"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InvestmentsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#InvestmentsDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/InvestmentsDetails" xlink:type="extended" id="i241b1ae7466a40619f13a79247c512d7_InvestmentsDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_a62ccaaa-05c1-48fb-b4b5-5d8d53c4097a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_1400da32-2299-4de4-811a-3c56c706d1e5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_a62ccaaa-05c1-48fb-b4b5-5d8d53c4097a" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_1400da32-2299-4de4-811a-3c56c706d1e5" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_54d2ca50-57da-419c-89ca-9af04ad87176" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_a62ccaaa-05c1-48fb-b4b5-5d8d53c4097a" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_54d2ca50-57da-419c-89ca-9af04ad87176" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_9ab8a13f-49e2-492b-9217-d9e143f0f0cd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_a62ccaaa-05c1-48fb-b4b5-5d8d53c4097a" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_9ab8a13f-49e2-492b-9217-d9e143f0f0cd" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_1b522a93-eda1-4674-b271-2238b1b70756" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_a62ccaaa-05c1-48fb-b4b5-5d8d53c4097a" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_1b522a93-eda1-4674-b271-2238b1b70756" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_ac09d47f-0104-47c5-b935-c9f3750782ae" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_a62ccaaa-05c1-48fb-b4b5-5d8d53c4097a" xlink:to="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_ac09d47f-0104-47c5-b935-c9f3750782ae" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_502e3d69-6e40-4278-a110-24f4eabb4630" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_ac09d47f-0104-47c5-b935-c9f3750782ae" xlink:to="loc_us-gaap_FinancialInstrumentAxis_502e3d69-6e40-4278-a110-24f4eabb4630" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_502e3d69-6e40-4278-a110-24f4eabb4630_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FinancialInstrumentAxis_502e3d69-6e40-4278-a110-24f4eabb4630" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_502e3d69-6e40-4278-a110-24f4eabb4630_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FinancialInstrumentAxis_502e3d69-6e40-4278-a110-24f4eabb4630" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasurySecuritiesMember_65a61102-cd41-4b05-b60f-d302cf50a3ab" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USTreasurySecuritiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_us-gaap_USTreasurySecuritiesMember_65a61102-cd41-4b05-b60f-d302cf50a3ab" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasuryBillSecuritiesMember_f884fb1f-526a-4e7f-800c-4fe1cdb30134" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USTreasuryBillSecuritiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_us-gaap_USTreasuryBillSecuritiesMember_f884fb1f-526a-4e7f-800c-4fe1cdb30134" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_bc9ab264-03b8-4f5e-9d10-a5606810e8d0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USGovernmentAgenciesDebtSecuritiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_bc9ab264-03b8-4f5e-9d10-a5606810e8d0" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_ff5164c5-d2eb-4436-8368-ae56c08a45bc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignGovernmentDebtSecuritiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_ff5164c5-d2eb-4436-8368-ae56c08a45bc" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesFinancialMember_91e42795-e536-4833-b846-08f3f557688f" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesFinancialMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_amgn_CorporateDebtSecuritiesFinancialMember_91e42795-e536-4833-b846-08f3f557688f" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesIndustrialMember_9e5e513e-247b-4263-a1cb-078efe81e068" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesIndustrialMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_amgn_CorporateDebtSecuritiesIndustrialMember_9e5e513e-247b-4263-a1cb-078efe81e068" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesOtherMember_03c02b51-d8ef-402b-833d-a2c38743a3e9" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesOtherMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_amgn_CorporateDebtSecuritiesOtherMember_03c02b51-d8ef-402b-833d-a2c38743a3e9" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_5dee3023-a73c-48de-980e-51df1b5cc2bd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResidentialMortgageBackedSecuritiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_5dee3023-a73c-48de-980e-51df1b5cc2bd" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetBackedSecuritiesMember_268592ef-1506-4e02-94c4-e7a711a6fa50" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetBackedSecuritiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_us-gaap_AssetBackedSecuritiesMember_268592ef-1506-4e02-94c4-e7a711a6fa50" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MoneyMarketFundsMember_20a48b01-8e53-4472-af08-3d518ebff32b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MoneyMarketFundsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_us-gaap_MoneyMarketFundsMember_20a48b01-8e53-4472-af08-3d518ebff32b" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherShortTermInterestBearingSecuritiesMember_d7016f8f-3a97-4bd5-9041-56a0c0fd9baf" xlink:href="amgn-20210930.xsd#amgn_OtherShortTermInterestBearingSecuritiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_amgn_OtherShortTermInterestBearingSecuritiesMember_d7016f8f-3a97-4bd5-9041-56a0c0fd9baf" xlink:type="arc" order="10"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#InvestmentsFairValuesbyClassificationDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails" xlink:type="extended" id="i2ad481adde9b4d89a8484522da8064b2_InvestmentsFairValuesbyClassificationDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_ddd641b7-853a-4f1b-949d-80a2ea1164e8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract_803038e1-d64c-4683-ac19-94e5f7a08586" xlink:href="amgn-20210930.xsd#amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_ddd641b7-853a-4f1b-949d-80a2ea1164e8" xlink:to="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract_803038e1-d64c-4683-ac19-94e5f7a08586" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_041ffce8-103e-4148-8d29-85d23a06ea7c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract_803038e1-d64c-4683-ac19-94e5f7a08586" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_041ffce8-103e-4148-8d29-85d23a06ea7c" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_8ce72115-fc0d-44f1-8264-927bd7caba6e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract_803038e1-d64c-4683-ac19-94e5f7a08586" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_8ce72115-fc0d-44f1-8264-927bd7caba6e" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_99eb2ed3-fb07-4921-b9e4-b1d166af4940" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract_803038e1-d64c-4683-ac19-94e5f7a08586" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_99eb2ed3-fb07-4921-b9e4-b1d166af4940" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_63a78cbe-7587-46d5-9128-05bae29b685e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_ddd641b7-853a-4f1b-949d-80a2ea1164e8" xlink:to="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_63a78cbe-7587-46d5-9128-05bae29b685e" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_9b824acf-1681-415c-9445-d7bec1ca55a9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_63a78cbe-7587-46d5-9128-05bae29b685e" xlink:to="loc_us-gaap_FinancialInstrumentAxis_9b824acf-1681-415c-9445-d7bec1ca55a9" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_9b824acf-1681-415c-9445-d7bec1ca55a9_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FinancialInstrumentAxis_9b824acf-1681-415c-9445-d7bec1ca55a9" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_9b824acf-1681-415c-9445-d7bec1ca55a9_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_ff4d72e9-a405-4b8c-aba5-f564f687bf18" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FinancialInstrumentAxis_9b824acf-1681-415c-9445-d7bec1ca55a9" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_ff4d72e9-a405-4b8c-aba5-f564f687bf18" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AvailableForSalesInvestmentsMember_bdfe9f55-2574-4c03-bc8d-c1f04ddc80bb" xlink:href="amgn-20210930.xsd#amgn_AvailableForSalesInvestmentsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_ff4d72e9-a405-4b8c-aba5-f564f687bf18" xlink:to="loc_amgn_AvailableForSalesInvestmentsMember_bdfe9f55-2574-4c03-bc8d-c1f04ddc80bb" xlink:type="arc" order="0"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual" xlink:type="simple" xlink:href="amgn-20210930.xsd#InvestmentsEquitySecuritiesDetailsTextual"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual" xlink:type="extended" id="i2ee0b9d773e34f6a8071d835f338379f_InvestmentsEquitySecuritiesDetailsTextual">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6c0f24ca-f009-446e-abcf-92daa77833ed" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNi_abce743b-2485-45e6-a6ac-759c4b4e456b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesFvNi"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6c0f24ca-f009-446e-abcf-92daa77833ed" xlink:to="loc_us-gaap_EquitySecuritiesFvNi_abce743b-2485-45e6-a6ac-759c4b4e456b" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss_fd7a09dc-616c-431c-88ac-921546479281" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6c0f24ca-f009-446e-abcf-92daa77833ed" xlink:to="loc_us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss_fd7a09dc-616c-431c-88ac-921546479281" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount_c5750a92-8c8b-47c7-b3c0-d3c9b4683431" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6c0f24ca-f009-446e-abcf-92daa77833ed" xlink:to="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount_c5750a92-8c8b-47c7-b3c0-d3c9b4683431" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_ef2f4423-83b3-48f1-941b-121a18fe6135" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestments"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6c0f24ca-f009-446e-abcf-92daa77833ed" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_ef2f4423-83b3-48f1-941b-121a18fe6135" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount_948979d7-365d-455a-96e0-7da84252f778" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6c0f24ca-f009-446e-abcf-92daa77833ed" xlink:to="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount_948979d7-365d-455a-96e0-7da84252f778" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleTable_dc6b2bdd-0afe-4721-8141-1cb5d76f714f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6c0f24ca-f009-446e-abcf-92daa77833ed" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleTable_dc6b2bdd-0afe-4721-8141-1cb5d76f714f" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1be4c653-5c6c-4f7a-87fc-2131d528c824" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleTable_dc6b2bdd-0afe-4721-8141-1cb5d76f714f" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1be4c653-5c6c-4f7a-87fc-2131d528c824" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1be4c653-5c6c-4f7a-87fc-2131d528c824_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1be4c653-5c6c-4f7a-87fc-2131d528c824" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1be4c653-5c6c-4f7a-87fc-2131d528c824_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0652bf8f-25f5-4600-86d5-6b6847e79ebf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1be4c653-5c6c-4f7a-87fc-2131d528c824" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0652bf8f-25f5-4600-86d5-6b6847e79ebf" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_629fc006-e61b-4fb0-b4be-1cf525fc595e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0652bf8f-25f5-4600-86d5-6b6847e79ebf" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_629fc006-e61b-4fb0-b4be-1cf525fc595e" xlink:type="arc" order="0"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails" xlink:type="extended" id="if342a8580f88447a850e63e2b1cbdef0_InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestments_a9db1116-4110-4573-b496-2ca26dc8cf2a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestments"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_EquityMethodInvestments_a9db1116-4110-4573-b496-2ca26dc8cf2a" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentAggregateCost_cac31594-9473-46e0-bd73-b5d0cbd52f2a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentAggregateCost"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_EquityMethodInvestmentAggregateCost_cac31594-9473-46e0-bd73-b5d0cbd52f2a" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AlternativeInvestment_7d2eff53-c3a0-4f54-a727-a3f8923ee64e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AlternativeInvestment"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_AlternativeInvestment_7d2eff53-c3a0-4f54-a727-a3f8923ee64e" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AlternativeInvestmentNetGainLoss_054d42ef-f2f4-4753-a565-491e1717ec8f" xlink:href="amgn-20210930.xsd#amgn_AlternativeInvestmentNetGainLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_amgn_AlternativeInvestmentNetGainLoss_054d42ef-f2f4-4753-a565-491e1717ec8f" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_753723d4-5c40-4db5-a0e5-b9bac2e74a7e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentOwnershipPercentage"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_753723d4-5c40-4db5-a0e5-b9bac2e74a7e" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentQuotedMarketValue_9f3351dd-98e2-4963-adea-28fa74f636b8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentQuotedMarketValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_EquityMethodInvestmentQuotedMarketValue_9f3351dd-98e2-4963-adea-28fa74f636b8" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity_880496c1-b24c-4533-870d-c52060ddd27b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity_880496c1-b24c-4533-870d-c52060ddd27b" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_6fe43d66-7040-48de-b3a2-ebd2dab2aee5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_6fe43d66-7040-48de-b3a2-ebd2dab2aee5" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentsFairValueDisclosure_0a1a4c8b-96c6-47d4-8162-01365f7b31c9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentsFairValueDisclosure"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_EquityMethodInvestmentsFairValueDisclosure_0a1a4c8b-96c6-47d4-8162-01365f7b31c9" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_EquityMethodInvestmentChangeInCarryingValue_954a7685-d27a-4bcf-bec4-c0a134b10955" xlink:href="amgn-20210930.xsd#amgn_EquityMethodInvestmentChangeInCarryingValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_amgn_EquityMethodInvestmentChangeInCarryingValue_954a7685-d27a-4bcf-bec4-c0a134b10955" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_ba28fee1-39bf-4391-ae28-7479549f01c1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestments"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_ba28fee1-39bf-4391-ae28-7479549f01c1" xlink:type="arc" order="10"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity_7c373e6b-689e-4385-9193-a35e7b5d99c7" xlink:href="amgn-20210930.xsd#amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity_7c373e6b-689e-4385-9193-a35e7b5d99c7" xlink:type="arc" order="11"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_EquityMethodInvestmentChangeInCarryingValueOther_7480a973-c2a5-4de7-a22d-643b97b6ffd6" xlink:href="amgn-20210930.xsd#amgn_EquityMethodInvestmentChangeInCarryingValueOther"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_amgn_EquityMethodInvestmentChangeInCarryingValueOther_7480a973-c2a5-4de7-a22d-643b97b6ffd6" xlink:type="arc" order="12"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireEquityMethodInvestments_d20723b5-9bce-492e-9e09-bdfe795f0530" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireEquityMethodInvestments"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_PaymentsToAcquireEquityMethodInvestments_d20723b5-9bce-492e-9e09-bdfe795f0530" xlink:type="arc" order="13"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1_79beaec0-5790-4996-b1e2-b3459a71f8cc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1_79beaec0-5790-4996-b1e2-b3459a71f8cc" xlink:type="arc" order="14"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_f6592fe0-ed31-4f9c-a9a2-0eed67af7f0d" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:to="loc_srt_RangeAxis_f6592fe0-ed31-4f9c-a9a2-0eed67af7f0d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_f6592fe0-ed31-4f9c-a9a2-0eed67af7f0d_default" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_f6592fe0-ed31-4f9c-a9a2-0eed67af7f0d" xlink:to="loc_srt_RangeMember_f6592fe0-ed31-4f9c-a9a2-0eed67af7f0d_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_bc5316d4-4a2c-4886-8469-502a08f77c6a" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_f6592fe0-ed31-4f9c-a9a2-0eed67af7f0d" xlink:to="loc_srt_RangeMember_bc5316d4-4a2c-4886-8469-502a08f77c6a" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_160642ca-47e6-4547-9ff7-1a30f99bcd08" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MinimumMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_bc5316d4-4a2c-4886-8469-502a08f77c6a" xlink:to="loc_srt_MinimumMember_160642ca-47e6-4547-9ff7-1a30f99bcd08" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_e0126858-c223-45c4-811d-7e2a1a501cb2" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MaximumMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_bc5316d4-4a2c-4886-8469-502a08f77c6a" xlink:to="loc_srt_MaximumMember_e0126858-c223-45c4-811d-7e2a1a501cb2" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_61809484-e91a-4123-82a9-dde6423c6ef4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_61809484-e91a-4123-82a9-dde6423c6ef4" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_61809484-e91a-4123-82a9-dde6423c6ef4_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_61809484-e91a-4123-82a9-dde6423c6ef4" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_61809484-e91a-4123-82a9-dde6423c6ef4_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_f69df2ec-5c75-4aec-a100-6df710d14239" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_61809484-e91a-4123-82a9-dde6423c6ef4" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_f69df2ec-5c75-4aec-a100-6df710d14239" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_BeiGeneMember_02a19e17-37b3-4887-84d6-b74c1c71122d" xlink:href="amgn-20210930.xsd#amgn_BeiGeneMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_f69df2ec-5c75-4aec-a100-6df710d14239" xlink:to="loc_amgn_BeiGeneMember_02a19e17-37b3-4887-84d6-b74c1c71122d" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_NeumoraTherapeuticsIncMember_36007dd5-b635-4b06-bfb8-47ce46482da8" xlink:href="amgn-20210930.xsd#amgn_NeumoraTherapeuticsIncMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_f69df2ec-5c75-4aec-a100-6df710d14239" xlink:to="loc_amgn_NeumoraTherapeuticsIncMember_36007dd5-b635-4b06-bfb8-47ce46482da8" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeAxis_797d86fb-c466-41e9-8999-6c0597e4f9e1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:to="loc_us-gaap_InvestmentTypeAxis_797d86fb-c466-41e9-8999-6c0597e4f9e1" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeCategorizationMember_797d86fb-c466-41e9-8999-6c0597e4f9e1_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentTypeCategorizationMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_InvestmentTypeAxis_797d86fb-c466-41e9-8999-6c0597e4f9e1" xlink:to="loc_us-gaap_InvestmentTypeCategorizationMember_797d86fb-c466-41e9-8999-6c0597e4f9e1_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeCategorizationMember_17f78e7c-19ae-46a8-bf99-8c0f1f7f8a85" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentTypeCategorizationMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_InvestmentTypeAxis_797d86fb-c466-41e9-8999-6c0597e4f9e1" xlink:to="loc_us-gaap_InvestmentTypeCategorizationMember_17f78e7c-19ae-46a8-bf99-8c0f1f7f8a85" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_PartnershipInterestMember_bcc19985-e783-466d-8445-857f1932638b" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_PartnershipInterestMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember_17f78e7c-19ae-46a8-bf99-8c0f1f7f8a85" xlink:to="loc_srt_PartnershipInterestMember_bcc19985-e783-466d-8445-857f1932638b" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_03540ea3-d96e-462a-9c6a-0ec9578651a6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_03540ea3-d96e-462a-9c6a-0ec9578651a6" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_03540ea3-d96e-462a-9c6a-0ec9578651a6_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_03540ea3-d96e-462a-9c6a-0ec9578651a6" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_03540ea3-d96e-462a-9c6a-0ec9578651a6_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_420f8c49-c1a6-4da4-8629-9bb6e197c0e4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_03540ea3-d96e-462a-9c6a-0ec9578651a6" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_420f8c49-c1a6-4da4-8629-9bb6e197c0e4" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember_0b037561-b49a-4d41-9913-e1dbecd311a6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_420f8c49-c1a6-4da4-8629-9bb6e197c0e4" xlink:to="loc_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember_0b037561-b49a-4d41-9913-e1dbecd311a6" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_61bec9ed-8749-4346-b767-686772103073" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_61bec9ed-8749-4346-b767-686772103073" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_61bec9ed-8749-4346-b767-686772103073_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_61bec9ed-8749-4346-b767-686772103073" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_61bec9ed-8749-4346-b767-686772103073_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_3afb0699-cc28-4285-a467-f96d31586534" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_61bec9ed-8749-4346-b767-686772103073" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_3afb0699-cc28-4285-a467-f96d31586534" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_b27c1c0d-10a8-4ff0-b917-7cfe1df0b2e6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_3afb0699-cc28-4285-a467-f96d31586534" xlink:to="loc_us-gaap_SubsequentEventMember_b27c1c0d-10a8-4ff0-b917-7cfe1df0b2e6" xlink:type="arc" order="0"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails" xlink:type="extended" id="i90eea25e6a614810a50108a557b56ae7_GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_b6e2a943-d9a7-4501-a472-85e56a84ff92" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_c838ea69-87de-467b-af1f-8761d70408d4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_b6e2a943-d9a7-4501-a472-85e56a84ff92" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_c838ea69-87de-467b-af1f-8761d70408d4" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_57e46cb6-f4e6-444b-9ebe-4888aaf902ca" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_b6e2a943-d9a7-4501-a472-85e56a84ff92" xlink:to="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_57e46cb6-f4e6-444b-9ebe-4888aaf902ca" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_9bf36dae-2b87-437c-912d-c57990c84124" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_57e46cb6-f4e6-444b-9ebe-4888aaf902ca" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_9bf36dae-2b87-437c-912d-c57990c84124" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_9bf36dae-2b87-437c-912d-c57990c84124_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_9bf36dae-2b87-437c-912d-c57990c84124" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_9bf36dae-2b87-437c-912d-c57990c84124_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_c862744d-b32f-498e-8dd9-29712c071d56" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_9bf36dae-2b87-437c-912d-c57990c84124" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_c862744d-b32f-498e-8dd9-29712c071d56" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InProcessResearchAndDevelopmentMember_92670c44-6be1-4f45-91ba-b3f573d4fe3d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InProcessResearchAndDevelopmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_c862744d-b32f-498e-8dd9-29712c071d56" xlink:to="loc_us-gaap_InProcessResearchAndDevelopmentMember_92670c44-6be1-4f45-91ba-b3f573d4fe3d" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_65ffa905-1c76-4ea0-9d8a-4b095bea4498" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_4307a436-bb84-4e79-badd-c56566fb8458" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_65ffa905-1c76-4ea0-9d8a-4b095bea4498" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_4307a436-bb84-4e79-badd-c56566fb8458" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_d22a3714-9725-4d08-8767-8b5f3400fae4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_65ffa905-1c76-4ea0-9d8a-4b095bea4498" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_d22a3714-9725-4d08-8767-8b5f3400fae4" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_7f857929-1354-4a43-9947-274705edf818" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_65ffa905-1c76-4ea0-9d8a-4b095bea4498" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_7f857929-1354-4a43-9947-274705edf818" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_241b8f5b-d7f4-4543-a1f0-10f9a38d7108" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_65ffa905-1c76-4ea0-9d8a-4b095bea4498" xlink:to="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_241b8f5b-d7f4-4543-a1f0-10f9a38d7108" xlink:type="arc" order="2" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_53ba9f94-1ce7-47df-a4f5-9d1ccb2a96cb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_241b8f5b-d7f4-4543-a1f0-10f9a38d7108" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_53ba9f94-1ce7-47df-a4f5-9d1ccb2a96cb" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_53ba9f94-1ce7-47df-a4f5-9d1ccb2a96cb_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_53ba9f94-1ce7-47df-a4f5-9d1ccb2a96cb" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_53ba9f94-1ce7-47df-a4f5-9d1ccb2a96cb_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_32678af4-5a31-48da-9652-3aad68943efe" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_53ba9f94-1ce7-47df-a4f5-9d1ccb2a96cb" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_32678af4-5a31-48da-9652-3aad68943efe" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DevelopedTechnologyRightsMember_8bded74a-01ef-4660-90b6-7ea36d2cf644" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DevelopedTechnologyRightsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_32678af4-5a31-48da-9652-3aad68943efe" xlink:to="loc_us-gaap_DevelopedTechnologyRightsMember_8bded74a-01ef-4660-90b6-7ea36d2cf644" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LicensingAgreementsMember_55466aab-a592-4dd1-8e06-477c78f06652" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LicensingAgreementsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_32678af4-5a31-48da-9652-3aad68943efe" xlink:to="loc_us-gaap_LicensingAgreementsMember_55466aab-a592-4dd1-8e06-477c78f06652" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketingRelatedIntangibleAssetsMember_39fee953-3301-4126-bd12-8b47cad74afb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MarketingRelatedIntangibleAssetsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_32678af4-5a31-48da-9652-3aad68943efe" xlink:to="loc_us-gaap_MarketingRelatedIntangibleAssetsMember_39fee953-3301-4126-bd12-8b47cad74afb" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember_f3dcd2f0-6492-4852-bbb7-1bed6c8f087d" xlink:href="amgn-20210930.xsd#amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_32678af4-5a31-48da-9652-3aad68943efe" xlink:to="loc_amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember_f3dcd2f0-6492-4852-bbb7-1bed6c8f087d" xlink:type="arc" order="3"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails" xlink:type="extended" id="ifa076c413a454833b86ce6787ed366e7_FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_fdb29e68-21a2-4a70-a4bf-8c9a3b52845e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_fdb29e68-21a2-4a70-a4bf-8c9a3b52845e" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_568ad685-382d-4063-be2a-058ced9493ab" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_568ad685-382d-4063-be2a-058ced9493ab" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_d110d79a-0a12-46f8-8f2a-6b18a169c3ad" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_d110d79a-0a12-46f8-8f2a-6b18a169c3ad" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease_19431668-802b-41e9-b486-182c0ba65154" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease_19431668-802b-41e9-b486-182c0ba65154" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLongTermDebt_d4da2e54-e736-4b3f-8361-ab4d7ed04ec2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherLongTermDebt"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_OtherLongTermDebt_d4da2e54-e736-4b3f-8361-ab4d7ed04ec2" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_fb248b08-e9ae-46e5-9b24-4212047561cf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebt"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_LongTermDebt_fb248b08-e9ae-46e5-9b24-4212047561cf" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_804ced31-af9d-4d38-92cc-b41aacb36759" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_LongTermDebtCurrent_804ced31-af9d-4d38-92cc-b41aacb36759" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_096fc810-1cca-4445-8688-db67e9ccd7bf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_096fc810-1cca-4445-8688-db67e9ccd7bf" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_b9d1aa10-a111-4b19-9750-05b1a598642a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentFaceAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_b9d1aa10-a111-4b19-9750-05b1a598642a" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent_cb7fa4e8-0bc7-40ea-b6ce-7861ac06095b" xlink:href="amgn-20210930.xsd#amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent_cb7fa4e8-0bc7-40ea-b6ce-7861ac06095b" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_ad13080d-be65-47ed-94a2-93edfc65176d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_DebtInstrumentTable_ad13080d-be65-47ed-94a2-93edfc65176d" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_088a2c5c-9674-4b03-9e4b-13f5c0c88df3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_ad13080d-be65-47ed-94a2-93edfc65176d" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_088a2c5c-9674-4b03-9e4b-13f5c0c88df3" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_088a2c5c-9674-4b03-9e4b-13f5c0c88df3_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_088a2c5c-9674-4b03-9e4b-13f5c0c88df3" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_088a2c5c-9674-4b03-9e4b-13f5c0c88df3_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_d6a411cf-5c4d-486b-9707-c6e489ee2e1a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_088a2c5c-9674-4b03-9e4b-13f5c0c88df3" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_d6a411cf-5c4d-486b-9707-c6e489ee2e1a" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesPayableToBanksMember_4310b28e-dab7-4b4e-909a-03a706431a34" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NotesPayableToBanksMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_d6a411cf-5c4d-486b-9707-c6e489ee2e1a" xlink:to="loc_us-gaap_NotesPayableToBanksMember_4310b28e-dab7-4b4e-909a-03a706431a34" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_88ed0d38-b843-4336-8d56-48f0022b9271" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_ad13080d-be65-47ed-94a2-93edfc65176d" xlink:to="loc_us-gaap_DebtInstrumentAxis_88ed0d38-b843-4336-8d56-48f0022b9271" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_88ed0d38-b843-4336-8d56-48f0022b9271_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DebtInstrumentAxis_88ed0d38-b843-4336-8d56-48f0022b9271" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_88ed0d38-b843-4336-8d56-48f0022b9271_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DebtInstrumentAxis_88ed0d38-b843-4336-8d56-48f0022b9271" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointFiveZeroPercentNotesDue2020Member_4af966c6-7f87-4712-8b42-876d9391a1a3" xlink:href="amgn-20210930.xsd#amgn_FourPointFiveZeroPercentNotesDue2020Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FourPointFiveZeroPercentNotesDue2020Member_4af966c6-7f87-4712-8b42-876d9391a1a3" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_757520f7-c1f1-45f0-9f01-d191205eef31" xlink:href="amgn-20210930.xsd#amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_757520f7-c1f1-45f0-9f01-d191205eef31" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FloatingRateNotesDue2020Member_51f2c38d-ad52-4fe1-92b7-db937c90af86" xlink:href="amgn-20210930.xsd#amgn_FloatingRateNotesDue2020Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FloatingRateNotesDue2020Member_51f2c38d-ad52-4fe1-92b7-db937c90af86" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointTwoZeroNotesDue2020Member_a2fa0133-78e0-4eef-8bbf-04b3f49256a3" xlink:href="amgn-20210930.xsd#amgn_TwoPointTwoZeroNotesDue2020Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointTwoZeroNotesDue2020Member_a2fa0133-78e0-4eef-8bbf-04b3f49256a3" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointFourFivePercentNotesDue2020Member_f6a54a3d-02d0-416a-b32a-831e2ab1e550" xlink:href="amgn-20210930.xsd#amgn_ThreePointFourFivePercentNotesDue2020Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointFourFivePercentNotesDue2020Member_f6a54a3d-02d0-416a-b32a-831e2ab1e550" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointOneZeroPercentNotesDue2021Member_f6e5ff1e-4d44-4c63-a019-193a954c0d7f" xlink:href="amgn-20210930.xsd#amgn_FourPointOneZeroPercentNotesDue2021Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FourPointOneZeroPercentNotesDue2021Member_f6e5ff1e-4d44-4c63-a019-193a954c0d7f" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_b5e53404-6314-4f3e-9b3a-f4406e2c9974" xlink:href="amgn-20210930.xsd#amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_b5e53404-6314-4f3e-9b3a-f4406e2c9974" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_d486f7f4-dbeb-47e8-873a-d727c05835da" xlink:href="amgn-20210930.xsd#amgn_ThreePointEightSevenFivePercentNotesDue2021Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_d486f7f4-dbeb-47e8-873a-d727c05835da" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_be716109-47e1-4671-ac66-48f5aba7e213" xlink:href="amgn-20210930.xsd#amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_be716109-47e1-4671-ac66-48f5aba7e213" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_de615baf-0629-4cc4-9f17-ef5478080bc4" xlink:href="amgn-20210930.xsd#amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_de615baf-0629-4cc4-9f17-ef5478080bc4" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointSixFiveNotesDue2022Member_c0027964-4417-4d77-b85b-0940e5305a2b" xlink:href="amgn-20210930.xsd#amgn_TwoPointSixFiveNotesDue2022Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointSixFiveNotesDue2022Member_c0027964-4417-4d77-b85b-0940e5305a2b" xlink:type="arc" order="10"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_eb1c6536-38a0-4031-95c7-157f43fb742d" xlink:href="amgn-20210930.xsd#amgn_ThreePointSixTwoFivePercentNotesDue2022Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_eb1c6536-38a0-4031-95c7-157f43fb742d" xlink:type="arc" order="11"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_5716f2b9-fd52-440c-83c8-7894d127f589" xlink:href="amgn-20210930.xsd#amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_5716f2b9-fd52-440c-83c8-7894d127f589" xlink:type="arc" order="12"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_8caf08c4-fd60-4667-aebc-71d5e702d196" xlink:href="amgn-20210930.xsd#amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_8caf08c4-fd60-4667-aebc-71d5e702d196" xlink:type="arc" order="13"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_73e222c4-7ef6-4572-9b28-a2428d3b8161" xlink:href="amgn-20210930.xsd#amgn_ThreePointSixTwoFivePercentNotesDue2024Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_73e222c4-7ef6-4572-9b28-a2428d3b8161" xlink:type="arc" order="14"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember_4c923ac0-5714-44bc-8baa-7cf79aa24a23" xlink:href="amgn-20210930.xsd#amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember_4c923ac0-5714-44bc-8baa-7cf79aa24a23" xlink:type="arc" order="15"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_ee87a604-ac34-4acf-914d-d404ce160535" xlink:href="amgn-20210930.xsd#amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_ee87a604-ac34-4acf-914d-d404ce160535" xlink:type="arc" order="16"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_9c9be88a-e0cd-48b0-b843-dc19689c243b" xlink:href="amgn-20210930.xsd#amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_9c9be88a-e0cd-48b0-b843-dc19689c243b" xlink:type="arc" order="17"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_7f535730-4001-43ef-9213-5739d41aa1a2" xlink:href="amgn-20210930.xsd#amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_7f535730-4001-43ef-9213-5739d41aa1a2" xlink:type="arc" order="18"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_79926e5b-eb1c-46e6-a7a4-2e02db9f47c2" xlink:href="amgn-20210930.xsd#amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_79926e5b-eb1c-46e6-a7a4-2e02db9f47c2" xlink:type="arc" order="19"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember_312fed0a-9f78-4c4f-b19f-5aa8f5cd4d62" xlink:href="amgn-20210930.xsd#amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember_312fed0a-9f78-4c4f-b19f-5aa8f5cd4d62" xlink:type="arc" order="20"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointTwoZeroNotesDue2027Member_da37739e-7116-406a-8384-05fa1c190a98" xlink:href="amgn-20210930.xsd#amgn_ThreePointTwoZeroNotesDue2027Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointTwoZeroNotesDue2027Member_da37739e-7116-406a-8384-05fa1c190a98" xlink:type="arc" order="21"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointSixFivePercent2028NotesMember_44c80fb4-9dc9-4d7c-b6a3-593215fd4d0b" xlink:href="amgn-20210930.xsd#amgn_OnePointSixFivePercent2028NotesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_OnePointSixFivePercent2028NotesMember_44c80fb4-9dc9-4d7c-b6a3-593215fd4d0b" xlink:type="arc" order="22"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPercentPoundSterlingNotesDue2029Member_36d18026-117d-4313-8898-63d9d22ae3ca" xlink:href="amgn-20210930.xsd#amgn_FourPercentPoundSterlingNotesDue2029Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FourPercentPoundSterlingNotesDue2029Member_36d18026-117d-4313-8898-63d9d22ae3ca" xlink:type="arc" order="23"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointFourFivePercentNotesDue2030Member_bde81b0b-6ae4-45a6-a3a8-cf29a91cd9bc" xlink:href="amgn-20210930.xsd#amgn_TwoPointFourFivePercentNotesDue2030Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointFourFivePercentNotesDue2030Member_bde81b0b-6ae4-45a6-a3a8-cf29a91cd9bc" xlink:type="arc" order="24"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointThreeZeroPercentNotesDue2031Member_a19f7c54-8458-4374-948e-b170c0012463" xlink:href="amgn-20210930.xsd#amgn_TwoPointThreeZeroPercentNotesDue2031Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointThreeZeroPercentNotesDue2031Member_a19f7c54-8458-4374-948e-b170c0012463" xlink:type="arc" order="25"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointZeroPercent2032NotesMemberMember_dbf3a147-39f7-4168-95f8-790d2ce422db" xlink:href="amgn-20210930.xsd#amgn_TwoPointZeroPercent2032NotesMemberMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointZeroPercent2032NotesMemberMember_dbf3a147-39f7-4168-95f8-790d2ce422db" xlink:type="arc" order="26"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_6fc89102-eef3-42aa-91b8-5e4db26a8daf" xlink:href="amgn-20210930.xsd#amgn_SixPointThreeSevenFivePercentNotesDue2037Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_6fc89102-eef3-42aa-91b8-5e4db26a8daf" xlink:type="arc" order="27"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_SixPointNineZeroPercentNotesDue2038Member_95acd192-140a-43b7-ba7d-dfc98f107824" xlink:href="amgn-20210930.xsd#amgn_SixPointNineZeroPercentNotesDue2038Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_SixPointNineZeroPercentNotesDue2038Member_95acd192-140a-43b7-ba7d-dfc98f107824" xlink:type="arc" order="28"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_SixPointFourZeroPercentNotesDue2039Member_3cdbe74e-371a-4a32-b5e8-1ae08fc7f7be" xlink:href="amgn-20210930.xsd#amgn_SixPointFourZeroPercentNotesDue2039Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_SixPointFourZeroPercentNotesDue2039Member_3cdbe74e-371a-4a32-b5e8-1ae08fc7f7be" xlink:type="arc" order="29"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointOneFivePercentNotesDue2040Member_d0146d85-deff-44d3-91a5-a2b007696493" xlink:href="amgn-20210930.xsd#amgn_ThreePointOneFivePercentNotesDue2040Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointOneFivePercentNotesDue2040Member_d0146d85-deff-44d3-91a5-a2b007696493" xlink:type="arc" order="30"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointSevenFivePercentNotesDue2040Member_036f4812-8983-418e-9158-b9b97226b469" xlink:href="amgn-20210930.xsd#amgn_FivePointSevenFivePercentNotesDue2040Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FivePointSevenFivePercentNotesDue2040Member_036f4812-8983-418e-9158-b9b97226b469" xlink:type="arc" order="31"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointEightZeroPercent2041NotesMember_0eaa0ce1-6eed-416d-bc7c-c80b178f2e16" xlink:href="amgn-20210930.xsd#amgn_TwoPointEightZeroPercent2041NotesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointEightZeroPercent2041NotesMember_0eaa0ce1-6eed-416d-bc7c-c80b178f2e16" xlink:type="arc" order="32"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointNineFivePercentNotesDue2041Member_d22dd03d-1f1e-454a-b53c-5b8d852b2896" xlink:href="amgn-20210930.xsd#amgn_FourPointNineFivePercentNotesDue2041Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FourPointNineFivePercentNotesDue2041Member_d22dd03d-1f1e-454a-b53c-5b8d852b2896" xlink:type="arc" order="33"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointOneFivePercentNotesDue2041Member_481ab4aa-8eb4-4a25-b236-e4dd024d1fdf" xlink:href="amgn-20210930.xsd#amgn_FivePointOneFivePercentNotesDue2041Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FivePointOneFivePercentNotesDue2041Member_481ab4aa-8eb4-4a25-b236-e4dd024d1fdf" xlink:type="arc" order="34"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointSixFivePercentNotesDue2042Member_2e42e448-9351-4450-9a34-5aa7126be226" xlink:href="amgn-20210930.xsd#amgn_FivePointSixFivePercentNotesDue2042Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FivePointSixFivePercentNotesDue2042Member_2e42e448-9351-4450-9a34-5aa7126be226" xlink:type="arc" order="35"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointThreeSevenFivePercentNotesDue2043Member_4a96aab8-e74f-4e1d-9bad-242bc77ba9e1" xlink:href="amgn-20210930.xsd#amgn_FivePointThreeSevenFivePercentNotesDue2043Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FivePointThreeSevenFivePercentNotesDue2043Member_4a96aab8-e74f-4e1d-9bad-242bc77ba9e1" xlink:type="arc" order="36"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_81d5eeb4-c4c3-4159-bd2b-e9c5600f2b98" xlink:href="amgn-20210930.xsd#amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_81d5eeb4-c4c3-4159-bd2b-e9c5600f2b98" xlink:type="arc" order="37"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_fdaffd75-94c7-439d-94b9-57b74788d9bd" xlink:href="amgn-20210930.xsd#amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_fdaffd75-94c7-439d-94b9-57b74788d9bd" xlink:type="arc" order="38"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointThreeSevenFivePercentNotesDue2050Member_1c01b9ff-badb-4075-839f-3bfdbd921d48" xlink:href="amgn-20210930.xsd#amgn_ThreePointThreeSevenFivePercentNotesDue2050Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointThreeSevenFivePercentNotesDue2050Member_1c01b9ff-badb-4075-839f-3bfdbd921d48" xlink:type="arc" order="39"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_22f3c910-1df9-4868-8600-71985f78e20a" xlink:href="amgn-20210930.xsd#amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_22f3c910-1df9-4868-8600-71985f78e20a" xlink:type="arc" order="40"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_A300NotesDue20523002052NotesMember_ee19846b-156f-42cc-9b64-800474f8973c" xlink:href="amgn-20210930.xsd#amgn_A300NotesDue20523002052NotesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_A300NotesDue20523002052NotesMember_ee19846b-156f-42cc-9b64-800474f8973c" xlink:type="arc" order="41"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember_6761fcf9-fddf-402c-bb79-98fe47bf62bb" xlink:href="amgn-20210930.xsd#amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember_6761fcf9-fddf-402c-bb79-98fe47bf62bb" xlink:type="arc" order="42"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherNotesDue2097Member_e4869098-7d86-480a-800a-589202936ae9" xlink:href="amgn-20210930.xsd#amgn_OtherNotesDue2097Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_OtherNotesDue2097Member_e4869098-7d86-480a-800a-589202936ae9" xlink:type="arc" order="43"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/FinancingarrangementsDetailsTextual" xlink:type="simple" xlink:href="amgn-20210930.xsd#FinancingarrangementsDetailsTextual"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/FinancingarrangementsDetailsTextual" xlink:type="extended" id="i65d03220b1894d86acc8949ff1a8db3a_FinancingarrangementsDetailsTextual">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_14ec9b2d-647a-49dc-a474-cd0b6d454993" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_cfb0066c-ea21-46f0-aec5-aec2e8535a87" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14ec9b2d-647a-49dc-a474-cd0b6d454993" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_cfb0066c-ea21-46f0-aec5-aec2e8535a87" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_a62baad1-25cf-4d38-82f4-918e0f4d6e95" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14ec9b2d-647a-49dc-a474-cd0b6d454993" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_a62baad1-25cf-4d38-82f4-918e0f4d6e95" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_52963c18-75af-4f13-adf7-0bd33675760d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentFaceAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14ec9b2d-647a-49dc-a474-cd0b6d454993" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_52963c18-75af-4f13-adf7-0bd33675760d" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent_7bf27c6e-e0e6-4c01-ae76-c575783cda93" xlink:href="amgn-20210930.xsd#amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14ec9b2d-647a-49dc-a474-cd0b6d454993" xlink:to="loc_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent_7bf27c6e-e0e6-4c01-ae76-c575783cda93" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount_dd841c9f-4552-4b07-b1ee-404186d8e223" xlink:href="amgn-20210930.xsd#amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14ec9b2d-647a-49dc-a474-cd0b6d454993" xlink:to="loc_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount_dd841c9f-4552-4b07-b1ee-404186d8e223" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_2758bf5d-4533-4add-9e02-2982b7965919" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14ec9b2d-647a-49dc-a474-cd0b6d454993" xlink:to="loc_us-gaap_DebtInstrumentTable_2758bf5d-4533-4add-9e02-2982b7965919" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_beeb000a-0e44-43ce-9995-ab812cb2de9d" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_2758bf5d-4533-4add-9e02-2982b7965919" xlink:to="loc_srt_RangeAxis_beeb000a-0e44-43ce-9995-ab812cb2de9d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_beeb000a-0e44-43ce-9995-ab812cb2de9d_default" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_beeb000a-0e44-43ce-9995-ab812cb2de9d" xlink:to="loc_srt_RangeMember_beeb000a-0e44-43ce-9995-ab812cb2de9d_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_0535d903-8fc1-46a6-8ff6-16c38e2e07bd" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_beeb000a-0e44-43ce-9995-ab812cb2de9d" xlink:to="loc_srt_RangeMember_0535d903-8fc1-46a6-8ff6-16c38e2e07bd" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_5f1c7ec4-4dcb-416d-b2c7-21d61405fd1c" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MinimumMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_0535d903-8fc1-46a6-8ff6-16c38e2e07bd" xlink:to="loc_srt_MinimumMember_5f1c7ec4-4dcb-416d-b2c7-21d61405fd1c" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_c547812e-207c-46b0-8a42-7abc9d3e7499" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MaximumMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_0535d903-8fc1-46a6-8ff6-16c38e2e07bd" xlink:to="loc_srt_MaximumMember_c547812e-207c-46b0-8a42-7abc9d3e7499" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_04941e4f-619c-40f0-bad4-40a484f62887" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_2758bf5d-4533-4add-9e02-2982b7965919" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_04941e4f-619c-40f0-bad4-40a484f62887" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_04941e4f-619c-40f0-bad4-40a484f62887_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_04941e4f-619c-40f0-bad4-40a484f62887" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_04941e4f-619c-40f0-bad4-40a484f62887_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_07015ab7-01c3-41fe-889a-14f55a4242bd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_04941e4f-619c-40f0-bad4-40a484f62887" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_07015ab7-01c3-41fe-889a-14f55a4242bd" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesPayableToBanksMember_4c04f847-aa07-4c5b-8f4d-102930105e4d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NotesPayableToBanksMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_07015ab7-01c3-41fe-889a-14f55a4242bd" xlink:to="loc_us-gaap_NotesPayableToBanksMember_4c04f847-aa07-4c5b-8f4d-102930105e4d" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesPayableMember_2394a7b2-ff31-42d6-8314-0da70c3bff70" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesPayableMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_07015ab7-01c3-41fe-889a-14f55a4242bd" xlink:to="loc_us-gaap_DebtSecuritiesPayableMember_2394a7b2-ff31-42d6-8314-0da70c3bff70" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_647ddc06-a42a-464c-87c8-a07d8b9b90b4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_2758bf5d-4533-4add-9e02-2982b7965919" xlink:to="loc_us-gaap_DebtInstrumentAxis_647ddc06-a42a-464c-87c8-a07d8b9b90b4" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_647ddc06-a42a-464c-87c8-a07d8b9b90b4_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DebtInstrumentAxis_647ddc06-a42a-464c-87c8-a07d8b9b90b4" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_647ddc06-a42a-464c-87c8-a07d8b9b90b4_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DebtInstrumentAxis_647ddc06-a42a-464c-87c8-a07d8b9b90b4" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_5ef57bdf-756a-4b3c-bfeb-f59bc65b15f5" xlink:href="amgn-20210930.xsd#amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:to="loc_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_5ef57bdf-756a-4b3c-bfeb-f59bc65b15f5" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_29964810-e523-4a2e-aae9-3d92dabf26f4" xlink:href="amgn-20210930.xsd#amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:to="loc_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_29964810-e523-4a2e-aae9-3d92dabf26f4" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember_ddcbfb3a-cb51-4d7d-b659-bad6f71fa986" xlink:href="amgn-20210930.xsd#amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:to="loc_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember_ddcbfb3a-cb51-4d7d-b659-bad6f71fa986" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointSixFivePercent2028NotesMember_16e0d392-87bf-439b-9407-6e256241777b" xlink:href="amgn-20210930.xsd#amgn_OnePointSixFivePercent2028NotesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:to="loc_amgn_OnePointSixFivePercent2028NotesMember_16e0d392-87bf-439b-9407-6e256241777b" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointZeroPercent2032NotesMemberMember_1f08906d-d837-4326-ba46-543c067e1826" xlink:href="amgn-20210930.xsd#amgn_TwoPointZeroPercent2032NotesMemberMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:to="loc_amgn_TwoPointZeroPercent2032NotesMemberMember_1f08906d-d837-4326-ba46-543c067e1826" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointEightZeroPercent2041NotesMember_6ba8987a-3362-4991-b6f4-878bf8dd9b77" xlink:href="amgn-20210930.xsd#amgn_TwoPointEightZeroPercent2041NotesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:to="loc_amgn_TwoPointEightZeroPercent2041NotesMember_6ba8987a-3362-4991-b6f4-878bf8dd9b77" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_A300NotesDue20523002052NotesMember_40d682f6-da8c-4494-9aea-924ee006d7ce" xlink:href="amgn-20210930.xsd#amgn_A300NotesDue20523002052NotesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:to="loc_amgn_A300NotesDue20523002052NotesMember_40d682f6-da8c-4494-9aea-924ee006d7ce" xlink:type="arc" order="6"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#FinancingarrangementsinterestrateswapstextualinterimonlyDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails" xlink:type="extended" id="i691a0bba3e6140f289ea025b5f24f8b1_FinancingarrangementsinterestrateswapstextualinterimonlyDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_5cc63d50-c34c-470a-b086-26683d7a533e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeNotionalAmount_c7aba347-965a-4c29-aa4d-8a01b6a99743" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeNotionalAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5cc63d50-c34c-470a-b086-26683d7a533e" xlink:to="loc_us-gaap_DerivativeNotionalAmount_c7aba347-965a-4c29-aa4d-8a01b6a99743" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_45fa52df-7af0-4814-9c8a-44bdd34b0901" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5cc63d50-c34c-470a-b086-26683d7a533e" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_45fa52df-7af0-4814-9c8a-44bdd34b0901" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeBasisSpreadOnVariableRate_27be2726-f3ef-4319-a9c4-914c7f0c8ee0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeBasisSpreadOnVariableRate"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5cc63d50-c34c-470a-b086-26683d7a533e" xlink:to="loc_us-gaap_DerivativeBasisSpreadOnVariableRate_27be2726-f3ef-4319-a9c4-914c7f0c8ee0" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_811ff76d-e984-4fa8-a333-c9a4e5091f00" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5cc63d50-c34c-470a-b086-26683d7a533e" xlink:to="loc_us-gaap_DebtInstrumentTable_811ff76d-e984-4fa8-a333-c9a4e5091f00" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_53651157-20f2-4440-affd-6d8be466b644" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_811ff76d-e984-4fa8-a333-c9a4e5091f00" xlink:to="loc_us-gaap_DebtInstrumentAxis_53651157-20f2-4440-affd-6d8be466b644" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_53651157-20f2-4440-affd-6d8be466b644_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DebtInstrumentAxis_53651157-20f2-4440-affd-6d8be466b644" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_53651157-20f2-4440-affd-6d8be466b644_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_4c51bcb6-64e5-42a6-8781-fb8575e4cfe7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DebtInstrumentAxis_53651157-20f2-4440-affd-6d8be466b644" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_4c51bcb6-64e5-42a6-8781-fb8575e4cfe7" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointFourFivePercentNotesDue2030Member_ab9b8c1c-d9f3-4cb9-ad0e-79199f838655" xlink:href="amgn-20210930.xsd#amgn_TwoPointFourFivePercentNotesDue2030Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_4c51bcb6-64e5-42a6-8781-fb8575e4cfe7" xlink:to="loc_amgn_TwoPointFourFivePercentNotesDue2030Member_ab9b8c1c-d9f3-4cb9-ad0e-79199f838655" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointThreeZeroPercentNotesDue2031Member_46681be0-a216-41c2-8505-376e983899ab" xlink:href="amgn-20210930.xsd#amgn_TwoPointThreeZeroPercentNotesDue2031Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_4c51bcb6-64e5-42a6-8781-fb8575e4cfe7" xlink:to="loc_amgn_TwoPointThreeZeroPercentNotesDue2031Member_46681be0-a216-41c2-8505-376e983899ab" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_e42f9ad3-67d9-4667-845d-d9a58d20fbf2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_811ff76d-e984-4fa8-a333-c9a4e5091f00" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_e42f9ad3-67d9-4667-845d-d9a58d20fbf2" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_e42f9ad3-67d9-4667-845d-d9a58d20fbf2_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_e42f9ad3-67d9-4667-845d-d9a58d20fbf2" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_e42f9ad3-67d9-4667-845d-d9a58d20fbf2_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_ca583ed8-0cf1-4401-a00c-a1e140a1072d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_e42f9ad3-67d9-4667-845d-d9a58d20fbf2" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_ca583ed8-0cf1-4401-a00c-a1e140a1072d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesPayableToBanksMember_e2b1de45-b351-4858-9681-20579d1b9ad1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NotesPayableToBanksMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_ca583ed8-0cf1-4401-a00c-a1e140a1072d" xlink:to="loc_us-gaap_NotesPayableToBanksMember_e2b1de45-b351-4858-9681-20579d1b9ad1" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateAxis_02ec207c-31a0-4891-8fe8-c89c99c8439a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_VariableRateAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_811ff76d-e984-4fa8-a333-c9a4e5091f00" xlink:to="loc_us-gaap_VariableRateAxis_02ec207c-31a0-4891-8fe8-c89c99c8439a" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateDomain_02ec207c-31a0-4891-8fe8-c89c99c8439a_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_VariableRateDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_VariableRateAxis_02ec207c-31a0-4891-8fe8-c89c99c8439a" xlink:to="loc_us-gaap_VariableRateDomain_02ec207c-31a0-4891-8fe8-c89c99c8439a_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateDomain_2c9bf048-0029-4868-9fb9-004b98cd7860" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_VariableRateDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_VariableRateAxis_02ec207c-31a0-4891-8fe8-c89c99c8439a" xlink:to="loc_us-gaap_VariableRateDomain_2c9bf048-0029-4868-9fb9-004b98cd7860" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_e85922aa-f9f9-4d2b-8cdd-bda9e9380ee2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LondonInterbankOfferedRateLIBORMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_VariableRateDomain_2c9bf048-0029-4868-9fb9-004b98cd7860" xlink:to="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_e85922aa-f9f9-4d2b-8cdd-bda9e9380ee2" xlink:type="arc" order="0"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/StockholdersequityDetailsTextualDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#StockholdersequityDetailsTextualDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/StockholdersequityDetailsTextualDetails" xlink:type="extended" id="i36cf06cb45cc41fd8d25c3d688df4042_StockholdersequityDetailsTextualDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_6c14c434-ff77-4ca9-a7b7-ee1fe2f10b66" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramAuthorizedAmount1_0975e861-5856-40d0-9611-3fb145ca7779" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchaseProgramAuthorizedAmount1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockLineItems_6c14c434-ff77-4ca9-a7b7-ee1fe2f10b66" xlink:to="loc_us-gaap_StockRepurchaseProgramAuthorizedAmount1_0975e861-5856-40d0-9611-3fb145ca7779" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_7575b07e-0ad8-4c3e-a3b5-e50427cd609e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockLineItems_6c14c434-ff77-4ca9-a7b7-ee1fe2f10b66" xlink:to="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_7575b07e-0ad8-4c3e-a3b5-e50427cd609e" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockDividendsPerShareDeclared_28f505d0-68f3-4978-b565-6338095b0e5c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockDividendsPerShareDeclared"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockLineItems_6c14c434-ff77-4ca9-a7b7-ee1fe2f10b66" xlink:to="loc_us-gaap_CommonStockDividendsPerShareDeclared_28f505d0-68f3-4978-b565-6338095b0e5c" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockDividendsPerShareCashPaid_d7424013-20cf-47e9-bb5d-f646a85e4216" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockDividendsPerShareCashPaid"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockLineItems_6c14c434-ff77-4ca9-a7b7-ee1fe2f10b66" xlink:to="loc_us-gaap_CommonStockDividendsPerShareCashPaid_d7424013-20cf-47e9-bb5d-f646a85e4216" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_396790c3-9e46-4088-a633-c6ee329431e7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ClassOfStockLineItems_6c14c434-ff77-4ca9-a7b7-ee1fe2f10b66" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_396790c3-9e46-4088-a633-c6ee329431e7" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementScenarioAxis_c71a16ec-2e64-4852-aae7-2b86ff2908a8" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_StatementScenarioAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_396790c3-9e46-4088-a633-c6ee329431e7" xlink:to="loc_srt_StatementScenarioAxis_c71a16ec-2e64-4852-aae7-2b86ff2908a8" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain_c71a16ec-2e64-4852-aae7-2b86ff2908a8_default" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ScenarioUnspecifiedDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_StatementScenarioAxis_c71a16ec-2e64-4852-aae7-2b86ff2908a8" xlink:to="loc_srt_ScenarioUnspecifiedDomain_c71a16ec-2e64-4852-aae7-2b86ff2908a8_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain_ba8ec5b4-734f-4d86-817c-403d5f3dcc8b" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ScenarioUnspecifiedDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_StatementScenarioAxis_c71a16ec-2e64-4852-aae7-2b86ff2908a8" xlink:to="loc_srt_ScenarioUnspecifiedDomain_ba8ec5b4-734f-4d86-817c-403d5f3dcc8b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioForecastMember_a6913cf1-787d-4d75-b231-47a0ad3611bc" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ScenarioForecastMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ScenarioUnspecifiedDomain_ba8ec5b4-734f-4d86-817c-403d5f3dcc8b" xlink:to="loc_srt_ScenarioForecastMember_a6913cf1-787d-4d75-b231-47a0ad3611bc" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_afb0e5d6-3a3c-42ac-9815-8a711ad2ee60" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_396790c3-9e46-4088-a633-c6ee329431e7" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_afb0e5d6-3a3c-42ac-9815-8a711ad2ee60" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_afb0e5d6-3a3c-42ac-9815-8a711ad2ee60_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_afb0e5d6-3a3c-42ac-9815-8a711ad2ee60" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_afb0e5d6-3a3c-42ac-9815-8a711ad2ee60_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_72161dcb-131c-4642-97ef-b2e0cba2d86f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_afb0e5d6-3a3c-42ac-9815-8a711ad2ee60" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_72161dcb-131c-4642-97ef-b2e0cba2d86f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_9be879c8-81bc-421d-8222-3f8badef47ec" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_72161dcb-131c-4642-97ef-b2e0cba2d86f" xlink:to="loc_us-gaap_SubsequentEventMember_9be879c8-81bc-421d-8222-3f8badef47ec" xlink:type="arc" order="0"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#StockholdersequityComponentsofAOCIDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails" xlink:type="extended" id="iaedc7c28340847f493e88bea236403d4_StockholdersequityComponentsofAOCIDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_aab1666c-9699-433f-a160-bfc3c88f997c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_aab1666c-9699-433f-a160-bfc3c88f997c" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_28f39203-8577-4de6-98ab-324999f24492" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:to="loc_us-gaap_StockholdersEquity_28f39203-8577-4de6-98ab-324999f24492" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_770a9e72-99d3-44a0-a37a-c08fb40e6eea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_770a9e72-99d3-44a0-a37a-c08fb40e6eea" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent_a4c68551-1bea-4331-bd0f-310816049013" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:to="loc_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent_a4c68551-1bea-4331-bd0f-310816049013" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent_46acbf94-42c4-4803-9aa0-4c8e77e54148" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:to="loc_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent_46acbf94-42c4-4803-9aa0-4c8e77e54148" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax_9fe6eb5d-6b48-4765-bb52-484d31f4c770" xlink:href="amgn-20210930.xsd#amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:to="loc_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax_9fe6eb5d-6b48-4765-bb52-484d31f4c770" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1_f77c7279-8c4c-4d57-bcf0-d234cedaae39" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1_f77c7279-8c4c-4d57-bcf0-d234cedaae39" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_0bc6d631-5046-4803-b28c-631a74be16ae" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_5dea8f9f-ab51-4142-a2cd-4216099bc1af" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_aab1666c-9699-433f-a160-bfc3c88f997c" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_5dea8f9f-ab51-4142-a2cd-4216099bc1af" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_0509bca9-730c-4121-bed8-f581a46f1760" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_5dea8f9f-ab51-4142-a2cd-4216099bc1af" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_0509bca9-730c-4121-bed8-f581a46f1760" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_0509bca9-730c-4121-bed8-f581a46f1760_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_0509bca9-730c-4121-bed8-f581a46f1760" xlink:to="loc_us-gaap_EquityComponentDomain_0509bca9-730c-4121-bed8-f581a46f1760_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_ba4b5704-c8f2-44e4-9a2a-8f6760b0ae55" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_0509bca9-730c-4121-bed8-f581a46f1760" xlink:to="loc_us-gaap_EquityComponentDomain_ba4b5704-c8f2-44e4-9a2a-8f6760b0ae55" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedTranslationAdjustmentMember_dfc0f91f-2c23-4220-b07c-1a7d733e3531" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedTranslationAdjustmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_ba4b5704-c8f2-44e4-9a2a-8f6760b0ae55" xlink:to="loc_us-gaap_AccumulatedTranslationAdjustmentMember_dfc0f91f-2c23-4220-b07c-1a7d733e3531" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_295f3b53-fbf7-4861-bbd3-77327699aa0b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_ba4b5704-c8f2-44e4-9a2a-8f6760b0ae55" xlink:to="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_295f3b53-fbf7-4861-bbd3-77327699aa0b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember_94542e6a-7583-447f-a331-02d8a322e9d7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_ba4b5704-c8f2-44e4-9a2a-8f6760b0ae55" xlink:to="loc_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember_94542e6a-7583-447f-a331-02d8a322e9d7" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AccumulatedOtherAdjustmentAttributabletoParentMember_0b737372-05c6-4002-92c3-1ed607d2159b" xlink:href="amgn-20210930.xsd#amgn_AccumulatedOtherAdjustmentAttributabletoParentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_ba4b5704-c8f2-44e4-9a2a-8f6760b0ae55" xlink:to="loc_amgn_AccumulatedOtherAdjustmentAttributabletoParentMember_0b737372-05c6-4002-92c3-1ed607d2159b" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_9e37a4c0-d9bc-4430-aa3f-d638eab0e4b4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_ba4b5704-c8f2-44e4-9a2a-8f6760b0ae55" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_9e37a4c0-d9bc-4430-aa3f-d638eab0e4b4" xlink:type="arc" order="4"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#StockholdersequityReclassificationsoutofAOCIDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails" xlink:type="extended" id="i3b0152e95fff493387ad9eef6ca9803b_StockholdersequityReclassificationsoutofAOCIDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_027939de-b557-43d6-b829-b1b67fec7546" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_98625b91-9f61-4bb2-8ed3-a09f5b94635d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_027939de-b557-43d6-b829-b1b67fec7546" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_98625b91-9f61-4bb2-8ed3-a09f5b94635d" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_5e571f75-00c7-4d40-b9ca-3b9ae7edd0d8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NonoperatingIncomeExpense"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_027939de-b557-43d6-b829-b1b67fec7546" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_5e571f75-00c7-4d40-b9ca-3b9ae7edd0d8" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_03c6c1cc-7623-4468-b7ae-d961322b7533" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_027939de-b557-43d6-b829-b1b67fec7546" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_03c6c1cc-7623-4468-b7ae-d961322b7533" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_f2fbaff4-0af2-49ac-a059-cf7f367a1140" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_027939de-b557-43d6-b829-b1b67fec7546" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_f2fbaff4-0af2-49ac-a059-cf7f367a1140" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_349a71e8-11d0-43ca-9962-8f4ebae7f364" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_027939de-b557-43d6-b829-b1b67fec7546" xlink:to="loc_us-gaap_NetIncomeLoss_349a71e8-11d0-43ca-9962-8f4ebae7f364" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_027939de-b557-43d6-b829-b1b67fec7546" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_3a09f67e-087b-4d0e-a36b-e0ad60e5d254" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_3a09f67e-087b-4d0e-a36b-e0ad60e5d254" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_3a09f67e-087b-4d0e-a36b-e0ad60e5d254_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_3a09f67e-087b-4d0e-a36b-e0ad60e5d254" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_3a09f67e-087b-4d0e-a36b-e0ad60e5d254_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_db58e41e-efca-4d2a-a6ba-ffcf3a435791" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_3a09f67e-087b-4d0e-a36b-e0ad60e5d254" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_db58e41e-efca-4d2a-a6ba-ffcf3a435791" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_21d8896d-8224-4454-a375-debe3ae5b6bd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_db58e41e-efca-4d2a-a6ba-ffcf3a435791" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_21d8896d-8224-4454-a375-debe3ae5b6bd" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_c308d4bf-38f3-4f86-a21a-870e005b9203" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_c308d4bf-38f3-4f86-a21a-870e005b9203" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_c308d4bf-38f3-4f86-a21a-870e005b9203_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_c308d4bf-38f3-4f86-a21a-870e005b9203" xlink:to="loc_us-gaap_HedgingRelationshipDomain_c308d4bf-38f3-4f86-a21a-870e005b9203_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_7e9df12a-fcee-4e74-a28c-8cabe339c85d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_c308d4bf-38f3-4f86-a21a-870e005b9203" xlink:to="loc_us-gaap_HedgingRelationshipDomain_7e9df12a-fcee-4e74-a28c-8cabe339c85d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgingMember_fef45c42-cd37-4282-b864-9e05f2e86aee" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashFlowHedgingMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_7e9df12a-fcee-4e74-a28c-8cabe339c85d" xlink:to="loc_us-gaap_CashFlowHedgingMember_fef45c42-cd37-4282-b864-9e05f2e86aee" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_b8528da5-cfa9-437e-b835-87e042aa95a2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_b8528da5-cfa9-437e-b835-87e042aa95a2" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_b8528da5-cfa9-437e-b835-87e042aa95a2_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_b8528da5-cfa9-437e-b835-87e042aa95a2" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_b8528da5-cfa9-437e-b835-87e042aa95a2_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_cf847c0f-6a68-40cb-8bba-9f4c8c35ebfe" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_b8528da5-cfa9-437e-b835-87e042aa95a2" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_cf847c0f-6a68-40cb-8bba-9f4c8c35ebfe" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember_9f2beaef-00d7-4d18-af9c-d9b4529389a7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_cf847c0f-6a68-40cb-8bba-9f4c8c35ebfe" xlink:to="loc_us-gaap_ForeignExchangeContractMember_9f2beaef-00d7-4d18-af9c-d9b4529389a7" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CrossCurrencySwapContractsMember_46196dca-907c-4137-b9b5-ddb97a5e84f9" xlink:href="amgn-20210930.xsd#amgn_CrossCurrencySwapContractsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_cf847c0f-6a68-40cb-8bba-9f4c8c35ebfe" xlink:to="loc_amgn_CrossCurrencySwapContractsMember_46196dca-907c-4137-b9b5-ddb97a5e84f9" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_1012c4d2-ba25-41d5-92e0-6f6a17c6fa63" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_1012c4d2-ba25-41d5-92e0-6f6a17c6fa63" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_1012c4d2-ba25-41d5-92e0-6f6a17c6fa63_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_1012c4d2-ba25-41d5-92e0-6f6a17c6fa63" xlink:to="loc_us-gaap_EquityComponentDomain_1012c4d2-ba25-41d5-92e0-6f6a17c6fa63_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_20e6ea85-0264-40fa-a493-3b2fc3a267f7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_1012c4d2-ba25-41d5-92e0-6f6a17c6fa63" xlink:to="loc_us-gaap_EquityComponentDomain_20e6ea85-0264-40fa-a493-3b2fc3a267f7" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_b7720206-d2de-422d-aeb8-057af5dcab5b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_20e6ea85-0264-40fa-a493-3b2fc3a267f7" xlink:to="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_b7720206-d2de-422d-aeb8-057af5dcab5b" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember_f5df7967-ce0c-465f-a420-ba2ab49f0fe1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_20e6ea85-0264-40fa-a493-3b2fc3a267f7" xlink:to="loc_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember_f5df7967-ce0c-465f-a420-ba2ab49f0fe1" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_06f0c5c7-f86c-4c7c-8478-92e1665832a4" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductOrServiceAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:to="loc_srt_ProductOrServiceAxis_06f0c5c7-f86c-4c7c-8478-92e1665832a4" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_06f0c5c7-f86c-4c7c-8478-92e1665832a4_default" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ProductOrServiceAxis_06f0c5c7-f86c-4c7c-8478-92e1665832a4" xlink:to="loc_srt_ProductsAndServicesDomain_06f0c5c7-f86c-4c7c-8478-92e1665832a4_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_270fd7f0-70af-44a5-8a94-cf4f3e4641a1" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ProductOrServiceAxis_06f0c5c7-f86c-4c7c-8478-92e1665832a4" xlink:to="loc_srt_ProductsAndServicesDomain_270fd7f0-70af-44a5-8a94-cf4f3e4641a1" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_252b4dfe-9b5f-458c-83ba-e41735ec4161" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_270fd7f0-70af-44a5-8a94-cf4f3e4641a1" xlink:to="loc_us-gaap_ProductMember_252b4dfe-9b5f-458c-83ba-e41735ec4161" xlink:type="arc" order="0"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/FairvaluemeasurementDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#FairvaluemeasurementDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/FairvaluemeasurementDetails" xlink:type="extended" id="i9cc0853ae5c04f6aa2c3d5642dc9b37f_FairvaluemeasurementDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_993b119c-91a8-451b-8405-c82412e5e4d4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosureAbstract_4830e02e-0363-45eb-af4d-736e64d48694" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsFairValueDisclosureAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_993b119c-91a8-451b-8405-c82412e5e4d4" xlink:to="loc_us-gaap_AssetsFairValueDisclosureAbstract_4830e02e-0363-45eb-af4d-736e64d48694" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_d59bf30f-5b51-45d6-b39c-d0e188f57705" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_4830e02e-0363-45eb-af4d-736e64d48694" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_d59bf30f-5b51-45d6-b39c-d0e188f57705" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNi_df8d9006-dd86-470f-93f0-7138730b1af5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesFvNi"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_4830e02e-0363-45eb-af4d-736e64d48694" xlink:to="loc_us-gaap_EquitySecuritiesFvNi_df8d9006-dd86-470f-93f0-7138730b1af5" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DerivativeAssetsFairValueDisclosureAbstract_ef24e271-d3af-43a5-a875-2921a9b0c9bc" xlink:href="amgn-20210930.xsd#amgn_DerivativeAssetsFairValueDisclosureAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_4830e02e-0363-45eb-af4d-736e64d48694" xlink:to="loc_amgn_DerivativeAssetsFairValueDisclosureAbstract_ef24e271-d3af-43a5-a875-2921a9b0c9bc" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure_af03c229-6e08-41a7-8c56-ef07b310cfff" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignCurrencyContractAssetFairValueDisclosure"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_amgn_DerivativeAssetsFairValueDisclosureAbstract_ef24e271-d3af-43a5-a875-2921a9b0c9bc" xlink:to="loc_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure_af03c229-6e08-41a7-8c56-ef07b310cfff" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateFairValueHedgeAssetAtFairValue_84cdbfe6-061f-4b6e-8d0a-2bb6c0a706dc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateFairValueHedgeAssetAtFairValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_amgn_DerivativeAssetsFairValueDisclosureAbstract_ef24e271-d3af-43a5-a875-2921a9b0c9bc" xlink:to="loc_us-gaap_InterestRateFairValueHedgeAssetAtFairValue_84cdbfe6-061f-4b6e-8d0a-2bb6c0a706dc" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_138b17bf-6ece-44b0-9526-e392176ee5af" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_4830e02e-0363-45eb-af4d-736e64d48694" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_138b17bf-6ece-44b0-9526-e392176ee5af" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_77889367-b105-43ff-9ee2-60290e1da71d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosureAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_993b119c-91a8-451b-8405-c82412e5e4d4" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_77889367-b105-43ff-9ee2-60290e1da71d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_0174f8d7-974b-492c-95e1-67bdeef8ba62" xlink:href="amgn-20210930.xsd#amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_77889367-b105-43ff-9ee2-60290e1da71d" xlink:to="loc_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_0174f8d7-974b-492c-95e1-67bdeef8ba62" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_3683a701-add8-4ea7-a946-51d2efc5ed52" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_0174f8d7-974b-492c-95e1-67bdeef8ba62" xlink:to="loc_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_3683a701-add8-4ea7-a946-51d2efc5ed52" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_6c701fa2-efc3-4b7f-8963-6ee08a13d189" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_0174f8d7-974b-492c-95e1-67bdeef8ba62" xlink:to="loc_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_6c701fa2-efc3-4b7f-8963-6ee08a13d189" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_5cb62aa4-8ffd-4e4e-b5ec-5fc7e79e430c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_0174f8d7-974b-492c-95e1-67bdeef8ba62" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_5cb62aa4-8ffd-4e4e-b5ec-5fc7e79e430c" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_fd298085-4471-408a-acb6-45c6bbfdcaea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_77889367-b105-43ff-9ee2-60290e1da71d" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosure_fd298085-4471-408a-acb6-45c6bbfdcaea" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_3254f57a-09f9-45e1-a40b-f0220870d0aa" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_993b119c-91a8-451b-8405-c82412e5e4d4" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_3254f57a-09f9-45e1-a40b-f0220870d0aa" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_4cb3cd75-3ae7-4855-86e9-799f48cee935" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_3254f57a-09f9-45e1-a40b-f0220870d0aa" xlink:to="loc_us-gaap_FinancialInstrumentAxis_4cb3cd75-3ae7-4855-86e9-799f48cee935" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_4cb3cd75-3ae7-4855-86e9-799f48cee935_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FinancialInstrumentAxis_4cb3cd75-3ae7-4855-86e9-799f48cee935" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_4cb3cd75-3ae7-4855-86e9-799f48cee935_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FinancialInstrumentAxis_4cb3cd75-3ae7-4855-86e9-799f48cee935" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasurySecuritiesMember_d12916a4-32c8-4b27-9e7c-b6e73bad384d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USTreasurySecuritiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_us-gaap_USTreasurySecuritiesMember_d12916a4-32c8-4b27-9e7c-b6e73bad384d" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasuryBillSecuritiesMember_a6b4eff2-118d-492b-a7d8-763edc26f143" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USTreasuryBillSecuritiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_us-gaap_USTreasuryBillSecuritiesMember_a6b4eff2-118d-492b-a7d8-763edc26f143" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_25605224-5735-4b1f-ac8e-cd255ab4bea2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USGovernmentAgenciesDebtSecuritiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_25605224-5735-4b1f-ac8e-cd255ab4bea2" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_4b6b5d2b-08f7-45dc-af86-02f7ae4aaf1a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignGovernmentDebtSecuritiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_4b6b5d2b-08f7-45dc-af86-02f7ae4aaf1a" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesFinancialMember_54b7aa0d-46e8-4552-919f-49804ce3a81a" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesFinancialMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_amgn_CorporateDebtSecuritiesFinancialMember_54b7aa0d-46e8-4552-919f-49804ce3a81a" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesIndustrialMember_643cf216-2ed1-45e3-8860-977e334d1cb3" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesIndustrialMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_amgn_CorporateDebtSecuritiesIndustrialMember_643cf216-2ed1-45e3-8860-977e334d1cb3" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesOtherMember_677a4215-ef85-43a7-9404-50168cac97da" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesOtherMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_amgn_CorporateDebtSecuritiesOtherMember_677a4215-ef85-43a7-9404-50168cac97da" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_b5f4b33f-a8e7-4e13-b1b1-e3dfea1f5e32" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResidentialMortgageBackedSecuritiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_b5f4b33f-a8e7-4e13-b1b1-e3dfea1f5e32" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetBackedSecuritiesMember_d3dd6030-f248-4e86-b7e0-50d462158d5d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetBackedSecuritiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_us-gaap_AssetBackedSecuritiesMember_d3dd6030-f248-4e86-b7e0-50d462158d5d" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MoneyMarketFundsMember_49acab65-c1ce-4ea9-9f40-d476116a068a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MoneyMarketFundsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_us-gaap_MoneyMarketFundsMember_49acab65-c1ce-4ea9-9f40-d476116a068a" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherShortTermInterestBearingSecuritiesMember_cd0da086-b517-4e96-aab4-9206aa970345" xlink:href="amgn-20210930.xsd#amgn_OtherShortTermInterestBearingSecuritiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_amgn_OtherShortTermInterestBearingSecuritiesMember_cd0da086-b517-4e96-aab4-9206aa970345" xlink:type="arc" order="10"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_334d60c9-d6a6-4bfb-9e82-1b3c0cbeca97" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_3254f57a-09f9-45e1-a40b-f0220870d0aa" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_334d60c9-d6a6-4bfb-9e82-1b3c0cbeca97" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_334d60c9-d6a6-4bfb-9e82-1b3c0cbeca97_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_334d60c9-d6a6-4bfb-9e82-1b3c0cbeca97" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_334d60c9-d6a6-4bfb-9e82-1b3c0cbeca97_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_22dc9423-5348-4537-a845-93c64fd9def0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_334d60c9-d6a6-4bfb-9e82-1b3c0cbeca97" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_22dc9423-5348-4537-a845-93c64fd9def0" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_87a3e4ca-6bf1-492d-8507-5694055520c3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_22dc9423-5348-4537-a845-93c64fd9def0" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_87a3e4ca-6bf1-492d-8507-5694055520c3" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_0065aec3-12c2-4250-81eb-5c87aeb68831" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel2Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_22dc9423-5348-4537-a845-93c64fd9def0" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_0065aec3-12c2-4250-81eb-5c87aeb68831" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_e594a643-fee3-494e-a7c8-fb930814ba3d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel3Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_22dc9423-5348-4537-a845-93c64fd9def0" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_e594a643-fee3-494e-a7c8-fb930814ba3d" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_b8442367-6cf0-4c39-92d8-fcd0088ff1d6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_3254f57a-09f9-45e1-a40b-f0220870d0aa" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_b8442367-6cf0-4c39-92d8-fcd0088ff1d6" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_b8442367-6cf0-4c39-92d8-fcd0088ff1d6_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_b8442367-6cf0-4c39-92d8-fcd0088ff1d6" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_b8442367-6cf0-4c39-92d8-fcd0088ff1d6_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_59922e29-ae1f-4725-b2c5-935f33a8bc09" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_b8442367-6cf0-4c39-92d8-fcd0088ff1d6" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_59922e29-ae1f-4725-b2c5-935f33a8bc09" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember_732a4583-c3dc-4821-a3cc-f0a1c8f31699" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_59922e29-ae1f-4725-b2c5-935f33a8bc09" xlink:to="loc_us-gaap_ForeignExchangeContractMember_732a4583-c3dc-4821-a3cc-f0a1c8f31699" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CrossCurrencySwapContractsMember_e07e66c8-6be5-4e29-bc7e-20ce9f200a64" xlink:href="amgn-20210930.xsd#amgn_CrossCurrencySwapContractsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_59922e29-ae1f-4725-b2c5-935f33a8bc09" xlink:to="loc_amgn_CrossCurrencySwapContractsMember_e07e66c8-6be5-4e29-bc7e-20ce9f200a64" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember_b80f715c-593b-4780-83ea-bcd5394d384e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateSwapMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_59922e29-ae1f-4725-b2c5-935f33a8bc09" xlink:to="loc_us-gaap_InterestRateSwapMember_b80f715c-593b-4780-83ea-bcd5394d384e" xlink:type="arc" order="2"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual" xlink:type="simple" xlink:href="amgn-20210930.xsd#DerivativeinstrumentsDetailsTextual"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual" xlink:type="extended" id="i4fee55ec5284429da442add864d40cca_DerivativeinstrumentsDetailsTextual">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_90a36aee-d650-40db-bcd0-33dcc1126b92" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeNotionalAmount_36301aa5-ebd8-4b1d-9e88-6220489d7e51" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeNotionalAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_90a36aee-d650-40db-bcd0-33dcc1126b92" xlink:to="loc_us-gaap_DerivativeNotionalAmount_36301aa5-ebd8-4b1d-9e88-6220489d7e51" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months_5c59b9ea-c34b-4362-b723-431ebb1066ba" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_90a36aee-d650-40db-bcd0-33dcc1126b92" xlink:to="loc_us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months_5c59b9ea-c34b-4362-b723-431ebb1066ba" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_348c50ab-17e6-4ad2-be5c-5ce8a457a669" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_90a36aee-d650-40db-bcd0-33dcc1126b92" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_348c50ab-17e6-4ad2-be5c-5ce8a457a669" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_90a36aee-d650-40db-bcd0-33dcc1126b92" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByLiabilityClassAxis_59cace25-f199-411f-ace0-ae576f13b756" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByLiabilityClassAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_us-gaap_FairValueByLiabilityClassAxis_59cace25-f199-411f-ace0-ae576f13b756" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_59cace25-f199-411f-ace0-ae576f13b756_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_59cace25-f199-411f-ace0-ae576f13b756" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_59cace25-f199-411f-ace0-ae576f13b756_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_0ce589c9-5a87-4e64-afe8-f03d46a37b1a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_59cace25-f199-411f-ace0-ae576f13b756" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_0ce589c9-5a87-4e64-afe8-f03d46a37b1a" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMember_fb6f82b2-1a2a-4eb2-a33b-70e810a50da3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_0ce589c9-5a87-4e64-afe8-f03d46a37b1a" xlink:to="loc_us-gaap_LongTermDebtMember_fb6f82b2-1a2a-4eb2-a33b-70e810a50da3" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_f7f201c5-af17-4a1a-9d78-35e9ce28230d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_f7f201c5-af17-4a1a-9d78-35e9ce28230d" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_f7f201c5-af17-4a1a-9d78-35e9ce28230d_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_f7f201c5-af17-4a1a-9d78-35e9ce28230d" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_f7f201c5-af17-4a1a-9d78-35e9ce28230d_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_fde69c5c-bb5c-4b28-92f3-010d52d737f3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_f7f201c5-af17-4a1a-9d78-35e9ce28230d" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_fde69c5c-bb5c-4b28-92f3-010d52d737f3" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationAxis_b4addb1e-4814-45d7-b1b9-551f64ce45e8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingDesignationAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_us-gaap_HedgingDesignationAxis_b4addb1e-4814-45d7-b1b9-551f64ce45e8" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_b4addb1e-4814-45d7-b1b9-551f64ce45e8_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingDesignationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_b4addb1e-4814-45d7-b1b9-551f64ce45e8" xlink:to="loc_us-gaap_HedgingDesignationDomain_b4addb1e-4814-45d7-b1b9-551f64ce45e8_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_06b6b9f8-9198-422a-8b1b-2b9658be5a07" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingDesignationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_b4addb1e-4814-45d7-b1b9-551f64ce45e8" xlink:to="loc_us-gaap_HedgingDesignationDomain_06b6b9f8-9198-422a-8b1b-2b9658be5a07" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_193a62b7-3e8a-4c29-93c9-efda5594937b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_06b6b9f8-9198-422a-8b1b-2b9658be5a07" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_193a62b7-3e8a-4c29-93c9-efda5594937b" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NondesignatedMember_010057d7-37d2-4b35-868e-366b110b4b37" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NondesignatedMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_06b6b9f8-9198-422a-8b1b-2b9658be5a07" xlink:to="loc_us-gaap_NondesignatedMember_010057d7-37d2-4b35-868e-366b110b4b37" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_82b3ea10-c79f-462b-b31c-942dc0118f93" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_82b3ea10-c79f-462b-b31c-942dc0118f93" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_82b3ea10-c79f-462b-b31c-942dc0118f93_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_82b3ea10-c79f-462b-b31c-942dc0118f93" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_82b3ea10-c79f-462b-b31c-942dc0118f93_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_6933ab0e-0593-4d7f-a94f-3595444966be" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_82b3ea10-c79f-462b-b31c-942dc0118f93" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_6933ab0e-0593-4d7f-a94f-3595444966be" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForwardContractsMember_62f10251-4a03-4584-a1b6-4a5f7215a3fb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForwardContractsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_6933ab0e-0593-4d7f-a94f-3595444966be" xlink:to="loc_us-gaap_ForwardContractsMember_62f10251-4a03-4584-a1b6-4a5f7215a3fb" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ForeignCurrencyAndCrossCurrencySwapsMember_7bce1572-5590-46a2-8693-b5430e4aaabb" xlink:href="amgn-20210930.xsd#amgn_ForeignCurrencyAndCrossCurrencySwapsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_6933ab0e-0593-4d7f-a94f-3595444966be" xlink:to="loc_amgn_ForeignCurrencyAndCrossCurrencySwapsMember_7bce1572-5590-46a2-8693-b5430e4aaabb" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember_9ffc129d-15a2-4bd2-a5c5-a1139cff4359" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateSwapMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_6933ab0e-0593-4d7f-a94f-3595444966be" xlink:to="loc_us-gaap_InterestRateSwapMember_9ffc129d-15a2-4bd2-a5c5-a1139cff4359" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_d7ee97ed-bdf7-40d1-a074-1ad2c59a8120" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_us-gaap_DebtInstrumentAxis_d7ee97ed-bdf7-40d1-a074-1ad2c59a8120" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_d7ee97ed-bdf7-40d1-a074-1ad2c59a8120_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DebtInstrumentAxis_d7ee97ed-bdf7-40d1-a074-1ad2c59a8120" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_d7ee97ed-bdf7-40d1-a074-1ad2c59a8120_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_03305bfc-0692-443d-b672-cb7433b44fea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DebtInstrumentAxis_d7ee97ed-bdf7-40d1-a074-1ad2c59a8120" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_03305bfc-0692-443d-b672-cb7433b44fea" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointFourFivePercentNotesDue2030Member_c71f6bd2-2351-48d7-8892-66a568100b53" xlink:href="amgn-20210930.xsd#amgn_TwoPointFourFivePercentNotesDue2030Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_03305bfc-0692-443d-b672-cb7433b44fea" xlink:to="loc_amgn_TwoPointFourFivePercentNotesDue2030Member_c71f6bd2-2351-48d7-8892-66a568100b53" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointThreeZeroPercentNotesDue2031Member_6f05dad8-2c00-4ee5-b52f-9067a4b742de" xlink:href="amgn-20210930.xsd#amgn_TwoPointThreeZeroPercentNotesDue2031Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_03305bfc-0692-443d-b672-cb7433b44fea" xlink:to="loc_amgn_TwoPointThreeZeroPercentNotesDue2031Member_6f05dad8-2c00-4ee5-b52f-9067a4b742de" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_d262bd13-a9dc-4f5d-a9dc-7fd3887bef81" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_d262bd13-a9dc-4f5d-a9dc-7fd3887bef81" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_d262bd13-a9dc-4f5d-a9dc-7fd3887bef81_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_d262bd13-a9dc-4f5d-a9dc-7fd3887bef81" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_d262bd13-a9dc-4f5d-a9dc-7fd3887bef81_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_d40c83a0-e90c-4c7f-a29f-c2005ac49ff9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_d262bd13-a9dc-4f5d-a9dc-7fd3887bef81" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_d40c83a0-e90c-4c7f-a29f-c2005ac49ff9" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesPayableToBanksMember_46f4269d-723b-4230-8e60-6278a4d7b959" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NotesPayableToBanksMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_d40c83a0-e90c-4c7f-a29f-c2005ac49ff9" xlink:to="loc_us-gaap_NotesPayableToBanksMember_46f4269d-723b-4230-8e60-6278a4d7b959" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DerivativeInstrumentNameAxis_2cfded0a-8769-4748-805d-e23d6985a8f3" xlink:href="amgn-20210930.xsd#amgn_DerivativeInstrumentNameAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_amgn_DerivativeInstrumentNameAxis_2cfded0a-8769-4748-805d-e23d6985a8f3" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DerivativeInstrumentNameDomain_2cfded0a-8769-4748-805d-e23d6985a8f3_default" xlink:href="amgn-20210930.xsd#amgn_DerivativeInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_amgn_DerivativeInstrumentNameAxis_2cfded0a-8769-4748-805d-e23d6985a8f3" xlink:to="loc_amgn_DerivativeInstrumentNameDomain_2cfded0a-8769-4748-805d-e23d6985a8f3_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DerivativeInstrumentNameDomain_69b5d704-fa03-459d-b1a0-996f6dc75e8f" xlink:href="amgn-20210930.xsd#amgn_DerivativeInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_amgn_DerivativeInstrumentNameAxis_2cfded0a-8769-4748-805d-e23d6985a8f3" xlink:to="loc_amgn_DerivativeInstrumentNameDomain_69b5d704-fa03-459d-b1a0-996f6dc75e8f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_A2030And2021NoteHedgesMember_3abbee80-d5f9-4861-a648-33e09dea94c9" xlink:href="amgn-20210930.xsd#amgn_A2030And2021NoteHedgesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_amgn_DerivativeInstrumentNameDomain_69b5d704-fa03-459d-b1a0-996f6dc75e8f" xlink:to="loc_amgn_A2030And2021NoteHedgesMember_3abbee80-d5f9-4861-a648-33e09dea94c9" xlink:type="arc" order="0"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#DerivativeinstrumentsCrosscurrencySwapsDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails" xlink:type="extended" id="i91187c0f30184514bbf9850436ea3edf_DerivativeinstrumentsCrosscurrencySwapsDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLineItems_c4aa70e3-a36e-4ba6-84ba-1e2ea8853f2a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeNotionalAmount_b0a92eb0-56cd-483d-a6de-c76925394ccd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeNotionalAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_c4aa70e3-a36e-4ba6-84ba-1e2ea8853f2a" xlink:to="loc_us-gaap_DerivativeNotionalAmount_b0a92eb0-56cd-483d-a6de-c76925394ccd" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFixedInterestRate_390e7eeb-d06b-4a4a-b142-6b36d378aa58" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeFixedInterestRate"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_c4aa70e3-a36e-4ba6-84ba-1e2ea8853f2a" xlink:to="loc_us-gaap_DerivativeFixedInterestRate_390e7eeb-d06b-4a4a-b142-6b36d378aa58" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeTable_48afce5a-317c-4a9d-bf25-5c0e1172bf7a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeLineItems_c4aa70e3-a36e-4ba6-84ba-1e2ea8853f2a" xlink:to="loc_us-gaap_DerivativeTable_48afce5a-317c-4a9d-bf25-5c0e1172bf7a" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_6d991916-1c40-4ca4-8f61-acf83c79574d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_48afce5a-317c-4a9d-bf25-5c0e1172bf7a" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_6d991916-1c40-4ca4-8f61-acf83c79574d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_6d991916-1c40-4ca4-8f61-acf83c79574d_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_6d991916-1c40-4ca4-8f61-acf83c79574d" xlink:to="loc_us-gaap_HedgingRelationshipDomain_6d991916-1c40-4ca4-8f61-acf83c79574d_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_31e6437a-8104-41bf-8782-d7c5368b0063" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_6d991916-1c40-4ca4-8f61-acf83c79574d" xlink:to="loc_us-gaap_HedgingRelationshipDomain_31e6437a-8104-41bf-8782-d7c5368b0063" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgingMember_a65ac1ac-554e-47d2-bec3-823af633ec6b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashFlowHedgingMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_31e6437a-8104-41bf-8782-d7c5368b0063" xlink:to="loc_us-gaap_CashFlowHedgingMember_a65ac1ac-554e-47d2-bec3-823af633ec6b" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_a9154491-9415-4ea6-8c7e-c513dfbfdda9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_48afce5a-317c-4a9d-bf25-5c0e1172bf7a" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_a9154491-9415-4ea6-8c7e-c513dfbfdda9" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_a9154491-9415-4ea6-8c7e-c513dfbfdda9_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_a9154491-9415-4ea6-8c7e-c513dfbfdda9" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_a9154491-9415-4ea6-8c7e-c513dfbfdda9_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_01e8780b-e137-45be-880c-b8b5f3bc4f02" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_a9154491-9415-4ea6-8c7e-c513dfbfdda9" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_01e8780b-e137-45be-880c-b8b5f3bc4f02" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CrossCurrencySwapContractsMember_88baae03-4fe2-43c8-80d6-83bf2776fc71" xlink:href="amgn-20210930.xsd#amgn_CrossCurrencySwapContractsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_01e8780b-e137-45be-880c-b8b5f3bc4f02" xlink:to="loc_amgn_CrossCurrencySwapContractsMember_88baae03-4fe2-43c8-80d6-83bf2776fc71" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CurrencyAxis_9a9afd81-9d8e-4f0b-820b-024495974319" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CurrencyAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_48afce5a-317c-4a9d-bf25-5c0e1172bf7a" xlink:to="loc_srt_CurrencyAxis_9a9afd81-9d8e-4f0b-820b-024495974319" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_currency_AllCurrenciesDomain_9a9afd81-9d8e-4f0b-820b-024495974319_default" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_AllCurrenciesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_CurrencyAxis_9a9afd81-9d8e-4f0b-820b-024495974319" xlink:to="loc_currency_AllCurrenciesDomain_9a9afd81-9d8e-4f0b-820b-024495974319_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_currency_AllCurrenciesDomain_6604c395-3883-4863-a13d-8fc070f326fc" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_AllCurrenciesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_CurrencyAxis_9a9afd81-9d8e-4f0b-820b-024495974319" xlink:to="loc_currency_AllCurrenciesDomain_6604c395-3883-4863-a13d-8fc070f326fc" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_currency_EUR_5882394e-259c-46e7-bb03-979a9e8e104d" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_EUR"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_currency_AllCurrenciesDomain_6604c395-3883-4863-a13d-8fc070f326fc" xlink:to="loc_currency_EUR_5882394e-259c-46e7-bb03-979a9e8e104d" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_currency_CHF_e6cb1acc-abfa-4591-8537-c998ebf5e751" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_CHF"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_currency_AllCurrenciesDomain_6604c395-3883-4863-a13d-8fc070f326fc" xlink:to="loc_currency_CHF_e6cb1acc-abfa-4591-8537-c998ebf5e751" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_currency_GBP_4f2066fa-3908-40ac-8242-74cd2e7ea948" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_GBP"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_currency_AllCurrenciesDomain_6604c395-3883-4863-a13d-8fc070f326fc" xlink:to="loc_currency_GBP_4f2066fa-3908-40ac-8242-74cd2e7ea948" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_currency_USD_dea145be-87da-485a-a0e9-13237c465efd" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_USD"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_currency_AllCurrenciesDomain_6604c395-3883-4863-a13d-8fc070f326fc" xlink:to="loc_currency_USD_dea145be-87da-485a-a0e9-13237c465efd" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_3a686517-6a11-4b1d-a173-0127d151369b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_48afce5a-317c-4a9d-bf25-5c0e1172bf7a" xlink:to="loc_us-gaap_DebtInstrumentAxis_3a686517-6a11-4b1d-a173-0127d151369b" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_3a686517-6a11-4b1d-a173-0127d151369b_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DebtInstrumentAxis_3a686517-6a11-4b1d-a173-0127d151369b" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_3a686517-6a11-4b1d-a173-0127d151369b_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_37d0f2e6-24a9-4a60-b62e-7b37bfe70bff" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DebtInstrumentAxis_3a686517-6a11-4b1d-a173-0127d151369b" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_37d0f2e6-24a9-4a60-b62e-7b37bfe70bff" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember_ea45f2d5-b9f1-49b1-913a-04370b7041a6" xlink:href="amgn-20210930.xsd#amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_37d0f2e6-24a9-4a60-b62e-7b37bfe70bff" xlink:to="loc_amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember_ea45f2d5-b9f1-49b1-913a-04370b7041a6" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_430a6a3a-9bd8-4361-86fa-41905f84cc56" xlink:href="amgn-20210930.xsd#amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_37d0f2e6-24a9-4a60-b62e-7b37bfe70bff" xlink:to="loc_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_430a6a3a-9bd8-4361-86fa-41905f84cc56" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_b7952098-b8bb-495d-bda1-415184f37b0e" xlink:href="amgn-20210930.xsd#amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_37d0f2e6-24a9-4a60-b62e-7b37bfe70bff" xlink:to="loc_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_b7952098-b8bb-495d-bda1-415184f37b0e" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_5dcead17-6c34-43c5-912e-4d2547712ad4" xlink:href="amgn-20210930.xsd#amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_37d0f2e6-24a9-4a60-b62e-7b37bfe70bff" xlink:to="loc_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_5dcead17-6c34-43c5-912e-4d2547712ad4" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPercentPoundSterlingNotesDue2029Member_aff5c601-d259-4016-9b7c-ee42d7c38177" xlink:href="amgn-20210930.xsd#amgn_FourPercentPoundSterlingNotesDue2029Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_37d0f2e6-24a9-4a60-b62e-7b37bfe70bff" xlink:to="loc_amgn_FourPercentPoundSterlingNotesDue2029Member_aff5c601-d259-4016-9b7c-ee42d7c38177" xlink:type="arc" order="4"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails" xlink:type="extended" id="i36ecffa354994e4aa5a3885268e678ae_DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_dd5d8737-d3d9-4e6e-ad15-c6b5261b90b6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax_7b45aea6-0939-4404-a318-64bf01339642" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_dd5d8737-d3d9-4e6e-ad15-c6b5261b90b6" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax_7b45aea6-0939-4404-a318-64bf01339642" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_87f75a0f-62a2-4e0e-934a-b870cc8dda90" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_dd5d8737-d3d9-4e6e-ad15-c6b5261b90b6" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_87f75a0f-62a2-4e0e-934a-b870cc8dda90" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_d8394c2d-d301-4bc5-9382-13335df93c64" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_87f75a0f-62a2-4e0e-934a-b870cc8dda90" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_d8394c2d-d301-4bc5-9382-13335df93c64" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_d8394c2d-d301-4bc5-9382-13335df93c64_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_d8394c2d-d301-4bc5-9382-13335df93c64" xlink:to="loc_us-gaap_HedgingRelationshipDomain_d8394c2d-d301-4bc5-9382-13335df93c64_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_0fbc60ea-6a66-44de-a447-6fe59328d6ee" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_d8394c2d-d301-4bc5-9382-13335df93c64" xlink:to="loc_us-gaap_HedgingRelationshipDomain_0fbc60ea-6a66-44de-a447-6fe59328d6ee" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgingMember_67f297f0-b68f-4270-9f8b-14d061905c0a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashFlowHedgingMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_0fbc60ea-6a66-44de-a447-6fe59328d6ee" xlink:to="loc_us-gaap_CashFlowHedgingMember_67f297f0-b68f-4270-9f8b-14d061905c0a" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_5041c7f2-c36c-489d-9c2a-d347ddb1c3dd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_87f75a0f-62a2-4e0e-934a-b870cc8dda90" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_5041c7f2-c36c-489d-9c2a-d347ddb1c3dd" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_5041c7f2-c36c-489d-9c2a-d347ddb1c3dd_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_5041c7f2-c36c-489d-9c2a-d347ddb1c3dd" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_5041c7f2-c36c-489d-9c2a-d347ddb1c3dd_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_f0fac6f9-6308-47c4-a3b3-6d5602ba2a2e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_5041c7f2-c36c-489d-9c2a-d347ddb1c3dd" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_f0fac6f9-6308-47c4-a3b3-6d5602ba2a2e" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember_b08f3727-0587-416e-bc08-d005fa577989" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_f0fac6f9-6308-47c4-a3b3-6d5602ba2a2e" xlink:to="loc_us-gaap_ForeignExchangeContractMember_b08f3727-0587-416e-bc08-d005fa577989" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CrossCurrencySwapContractsMember_e9a6585f-b21f-4f9a-970d-4837330c1e2a" xlink:href="amgn-20210930.xsd#amgn_CrossCurrencySwapContractsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_f0fac6f9-6308-47c4-a3b3-6d5602ba2a2e" xlink:to="loc_amgn_CrossCurrencySwapContractsMember_e9a6585f-b21f-4f9a-970d-4837330c1e2a" xlink:type="arc" order="1"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails" xlink:type="extended" id="id237011570f048f0a762c2ae4f2fb7f2_DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLineItems_d911e339-e924-473f-9115-ccae93bbe2df" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgedLiabilityFairValueHedge_1af59a8f-9c83-4072-877b-fa061deb157b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgedLiabilityFairValueHedge"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_d911e339-e924-473f-9115-ccae93bbe2df" xlink:to="loc_us-gaap_HedgedLiabilityFairValueHedge_1af59a8f-9c83-4072-877b-fa061deb157b" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease_5dbaf4c5-0797-4b2d-b54b-5376de6fe158" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_d911e339-e924-473f-9115-ccae93bbe2df" xlink:to="loc_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease_5dbaf4c5-0797-4b2d-b54b-5376de6fe158" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_HedgedLiabilityDiscontinuedFairValueHedge_eabb5722-647d-4b19-b116-cb6d812d6a6b" xlink:href="amgn-20210930.xsd#amgn_HedgedLiabilityDiscontinuedFairValueHedge"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_d911e339-e924-473f-9115-ccae93bbe2df" xlink:to="loc_amgn_HedgedLiabilityDiscontinuedFairValueHedge_eabb5722-647d-4b19-b116-cb6d812d6a6b" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease_63ca20cc-13ba-4906-9289-f3d340901667" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_d911e339-e924-473f-9115-ccae93bbe2df" xlink:to="loc_us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease_63ca20cc-13ba-4906-9289-f3d340901667" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeTable_4027a53b-b0b1-48e3-ba49-ff46a745e38b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeLineItems_d911e339-e924-473f-9115-ccae93bbe2df" xlink:to="loc_us-gaap_DerivativeTable_4027a53b-b0b1-48e3-ba49-ff46a745e38b" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByLiabilityClassAxis_a8082dc9-42ca-428a-9996-823389212acb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByLiabilityClassAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_4027a53b-b0b1-48e3-ba49-ff46a745e38b" xlink:to="loc_us-gaap_FairValueByLiabilityClassAxis_a8082dc9-42ca-428a-9996-823389212acb" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_a8082dc9-42ca-428a-9996-823389212acb_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_a8082dc9-42ca-428a-9996-823389212acb" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_a8082dc9-42ca-428a-9996-823389212acb_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_4e6520e4-2158-49ba-a6c6-417c49b7d47c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_a8082dc9-42ca-428a-9996-823389212acb" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_4e6520e4-2158-49ba-a6c6-417c49b7d47c" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LongTermDebtCurrentMaturitiesMember_9025b259-e72f-43fb-a0c5-b22c8375b4a9" xlink:href="amgn-20210930.xsd#amgn_LongTermDebtCurrentMaturitiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_4e6520e4-2158-49ba-a6c6-417c49b7d47c" xlink:to="loc_amgn_LongTermDebtCurrentMaturitiesMember_9025b259-e72f-43fb-a0c5-b22c8375b4a9" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMember_78ac143b-da7a-466d-a188-4d32ab91753f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_4e6520e4-2158-49ba-a6c6-417c49b7d47c" xlink:to="loc_us-gaap_LongTermDebtMember_78ac143b-da7a-466d-a188-4d32ab91753f" xlink:type="arc" order="1"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails" xlink:type="extended" id="ie589a96c801c437f94e83361ec53e055_DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_233c815e-fe54-4252-9237-9647f6366bcf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_91c1f03e-d6dd-45ab-8979-9de2351b8df4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_233c815e-fe54-4252-9237-9647f6366bcf" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_91c1f03e-d6dd-45ab-8979-9de2351b8df4" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_2605c90d-4d1e-49b3-ae29-c6ba047ba05f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NonoperatingIncomeExpense"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_233c815e-fe54-4252-9237-9647f6366bcf" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_2605c90d-4d1e-49b3-ae29-c6ba047ba05f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebt_d6ac1413-0ccf-4fa8-aedc-ac11c9882d37" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestExpenseDebt"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_233c815e-fe54-4252-9237-9647f6366bcf" xlink:to="loc_us-gaap_InterestExpenseDebt_d6ac1413-0ccf-4fa8-aedc-ac11c9882d37" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1_0197c83e-8233-4113-bfe9-c6415d23f506" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_233c815e-fe54-4252-9237-9647f6366bcf" xlink:to="loc_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1_0197c83e-8233-4113-bfe9-c6415d23f506" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1_5d96087f-c571-4ed0-901b-018f3d8dec7c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_233c815e-fe54-4252-9237-9647f6366bcf" xlink:to="loc_us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1_5d96087f-c571-4ed0-901b-018f3d8dec7c" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_958b2362-e40e-4855-9ef7-be526c60cae3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_233c815e-fe54-4252-9237-9647f6366bcf" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_958b2362-e40e-4855-9ef7-be526c60cae3" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_24625f0d-c362-4027-a97c-ca0232e305ff" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductOrServiceAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_958b2362-e40e-4855-9ef7-be526c60cae3" xlink:to="loc_srt_ProductOrServiceAxis_24625f0d-c362-4027-a97c-ca0232e305ff" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_24625f0d-c362-4027-a97c-ca0232e305ff_default" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ProductOrServiceAxis_24625f0d-c362-4027-a97c-ca0232e305ff" xlink:to="loc_srt_ProductsAndServicesDomain_24625f0d-c362-4027-a97c-ca0232e305ff_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_5153615a-4a9f-41c1-bbc4-a807ef313662" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ProductOrServiceAxis_24625f0d-c362-4027-a97c-ca0232e305ff" xlink:to="loc_srt_ProductsAndServicesDomain_5153615a-4a9f-41c1-bbc4-a807ef313662" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_74071d95-52a0-41bf-99f7-87441188bed3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_5153615a-4a9f-41c1-bbc4-a807ef313662" xlink:to="loc_us-gaap_ProductMember_74071d95-52a0-41bf-99f7-87441188bed3" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_b80c8996-6d99-4573-adcf-10c29287b3cb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_958b2362-e40e-4855-9ef7-be526c60cae3" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_b80c8996-6d99-4573-adcf-10c29287b3cb" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_b80c8996-6d99-4573-adcf-10c29287b3cb_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_b80c8996-6d99-4573-adcf-10c29287b3cb" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_b80c8996-6d99-4573-adcf-10c29287b3cb_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_68068efd-212b-41c2-9424-83104c2769ea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_b80c8996-6d99-4573-adcf-10c29287b3cb" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_68068efd-212b-41c2-9424-83104c2769ea" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_16a4d193-d9fa-4d84-aaa5-f066bc516769" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_68068efd-212b-41c2-9424-83104c2769ea" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_16a4d193-d9fa-4d84-aaa5-f066bc516769" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_d3c74e51-ec36-4ef2-8a50-139e4f75f5ae" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_958b2362-e40e-4855-9ef7-be526c60cae3" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_d3c74e51-ec36-4ef2-8a50-139e4f75f5ae" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_d3c74e51-ec36-4ef2-8a50-139e4f75f5ae_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_d3c74e51-ec36-4ef2-8a50-139e4f75f5ae" xlink:to="loc_us-gaap_EquityComponentDomain_d3c74e51-ec36-4ef2-8a50-139e4f75f5ae_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_0d98b614-433f-4112-9ed7-892845c77871" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_d3c74e51-ec36-4ef2-8a50-139e4f75f5ae" xlink:to="loc_us-gaap_EquityComponentDomain_0d98b614-433f-4112-9ed7-892845c77871" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_6c4d2f10-5cb5-4127-a763-99cb99b4f3f7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_0d98b614-433f-4112-9ed7-892845c77871" xlink:to="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_6c4d2f10-5cb5-4127-a763-99cb99b4f3f7" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_f289392f-e5fc-4a7a-99a3-6c7efb123534" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_958b2362-e40e-4855-9ef7-be526c60cae3" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_f289392f-e5fc-4a7a-99a3-6c7efb123534" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_f289392f-e5fc-4a7a-99a3-6c7efb123534_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_f289392f-e5fc-4a7a-99a3-6c7efb123534" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_f289392f-e5fc-4a7a-99a3-6c7efb123534_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_0ef0a904-189d-4e3b-a575-3921d8e5baa3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_f289392f-e5fc-4a7a-99a3-6c7efb123534" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_0ef0a904-189d-4e3b-a575-3921d8e5baa3" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember_39c6db4f-5ac8-4cac-a17f-26a76ef5cb12" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_0ef0a904-189d-4e3b-a575-3921d8e5baa3" xlink:to="loc_us-gaap_ForeignExchangeContractMember_39c6db4f-5ac8-4cac-a17f-26a76ef5cb12" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CrossCurrencySwapContractsMember_dbb9a9f4-3578-4601-9183-1daf754e4641" xlink:href="amgn-20210930.xsd#amgn_CrossCurrencySwapContractsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_0ef0a904-189d-4e3b-a575-3921d8e5baa3" xlink:to="loc_amgn_CrossCurrencySwapContractsMember_dbb9a9f4-3578-4601-9183-1daf754e4641" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember_e346355d-cffe-422f-b651-c5f0baf1f9f3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateSwapMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_0ef0a904-189d-4e3b-a575-3921d8e5baa3" xlink:to="loc_us-gaap_InterestRateSwapMember_e346355d-cffe-422f-b651-c5f0baf1f9f3" xlink:type="arc" order="2"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#DerivativeinstrumentsFairValueofDerivativesDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails" xlink:type="extended" id="ie6cfbdbc0840460ebbf442d02e19be78_DerivativeinstrumentsFairValueofDerivativesDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativesFairValueLineItems_a7723455-256e-4b65-bd6c-79bd919248f2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativesFairValueLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract_88b244b5-31cd-4282-8cd6-6c5cc6e67049" xlink:href="amgn-20210930.xsd#amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_a7723455-256e-4b65-bd6c-79bd919248f2" xlink:to="loc_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract_88b244b5-31cd-4282-8cd6-6c5cc6e67049" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssetFairValueNetAbstract_4f07d9b8-da31-4479-b4be-5489c152248b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeAssetFairValueNetAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract_88b244b5-31cd-4282-8cd6-6c5cc6e67049" xlink:to="loc_us-gaap_DerivativeAssetFairValueNetAbstract_4f07d9b8-da31-4479-b4be-5489c152248b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_4ae7c70e-3daf-485a-980a-2c36ddda69f5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeAsset"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeAssetFairValueNetAbstract_4f07d9b8-da31-4479-b4be-5489c152248b" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_4ae7c70e-3daf-485a-980a-2c36ddda69f5" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilityFairValueNetAbstract_af807093-c46a-4fc6-95a6-f4f1663c790e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeLiabilityFairValueNetAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract_88b244b5-31cd-4282-8cd6-6c5cc6e67049" xlink:to="loc_us-gaap_DerivativeLiabilityFairValueNetAbstract_af807093-c46a-4fc6-95a6-f4f1663c790e" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_1f8d3baf-72b0-4e82-9455-0717f1a2816f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeLiability"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLiabilityFairValueNetAbstract_af807093-c46a-4fc6-95a6-f4f1663c790e" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_1f8d3baf-72b0-4e82-9455-0717f1a2816f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_bdfec912-97ea-4581-badf-3c2c9d0cda0a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_a7723455-256e-4b65-bd6c-79bd919248f2" xlink:to="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_bdfec912-97ea-4581-badf-3c2c9d0cda0a" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationAxis_6dfb66ac-fa49-487a-930b-f57ec28abfa5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingDesignationAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_bdfec912-97ea-4581-badf-3c2c9d0cda0a" xlink:to="loc_us-gaap_HedgingDesignationAxis_6dfb66ac-fa49-487a-930b-f57ec28abfa5" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_6dfb66ac-fa49-487a-930b-f57ec28abfa5_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingDesignationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_6dfb66ac-fa49-487a-930b-f57ec28abfa5" xlink:to="loc_us-gaap_HedgingDesignationDomain_6dfb66ac-fa49-487a-930b-f57ec28abfa5_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_44748cbe-98f7-4654-85d7-6e444a8b1055" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingDesignationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_6dfb66ac-fa49-487a-930b-f57ec28abfa5" xlink:to="loc_us-gaap_HedgingDesignationDomain_44748cbe-98f7-4654-85d7-6e444a8b1055" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_976c58a8-4065-4725-9bda-69ef0d14e6a0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_44748cbe-98f7-4654-85d7-6e444a8b1055" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_976c58a8-4065-4725-9bda-69ef0d14e6a0" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NondesignatedMember_fef4dde4-1f20-47fb-9d87-47db9fe1f594" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NondesignatedMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_44748cbe-98f7-4654-85d7-6e444a8b1055" xlink:to="loc_us-gaap_NondesignatedMember_fef4dde4-1f20-47fb-9d87-47db9fe1f594" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_2d50f2ec-0756-43c6-87d8-ea01689efb83" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_bdfec912-97ea-4581-badf-3c2c9d0cda0a" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_2d50f2ec-0756-43c6-87d8-ea01689efb83" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_2d50f2ec-0756-43c6-87d8-ea01689efb83_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_2d50f2ec-0756-43c6-87d8-ea01689efb83" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_2d50f2ec-0756-43c6-87d8-ea01689efb83_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_f5b52be5-4b40-4955-bfa6-182585a59336" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_2d50f2ec-0756-43c6-87d8-ea01689efb83" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_f5b52be5-4b40-4955-bfa6-182585a59336" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember_283a244a-93b4-447d-954b-924884ee6b8b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_f5b52be5-4b40-4955-bfa6-182585a59336" xlink:to="loc_us-gaap_ForeignExchangeContractMember_283a244a-93b4-447d-954b-924884ee6b8b" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CrossCurrencySwapContractsMember_cba910d9-b9a6-41c3-82da-989c9890403e" xlink:href="amgn-20210930.xsd#amgn_CrossCurrencySwapContractsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_f5b52be5-4b40-4955-bfa6-182585a59336" xlink:to="loc_amgn_CrossCurrencySwapContractsMember_cba910d9-b9a6-41c3-82da-989c9890403e" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember_63d4b70a-406c-476d-b61a-ca4943446563" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateSwapMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_f5b52be5-4b40-4955-bfa6-182585a59336" xlink:to="loc_us-gaap_InterestRateSwapMember_63d4b70a-406c-476d-b61a-ca4943446563" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_73d994a1-7a4a-4951-bd59-c9ade06b2e4e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BalanceSheetLocationAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_bdfec912-97ea-4581-badf-3c2c9d0cda0a" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_73d994a1-7a4a-4951-bd59-c9ade06b2e4e" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_73d994a1-7a4a-4951-bd59-c9ade06b2e4e_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BalanceSheetLocationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_73d994a1-7a4a-4951-bd59-c9ade06b2e4e" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_73d994a1-7a4a-4951-bd59-c9ade06b2e4e_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_c3f21ea3-c4b5-4b4f-9f6f-01154d571224" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BalanceSheetLocationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_73d994a1-7a4a-4951-bd59-c9ade06b2e4e" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_c3f21ea3-c4b5-4b4f-9f6f-01154d571224" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherCurrentNoncurrentAssetsMember_2fcd3d93-23df-4b74-a86c-1dfb6221e3cf" xlink:href="amgn-20210930.xsd#amgn_OtherCurrentNoncurrentAssetsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_c3f21ea3-c4b5-4b4f-9f6f-01154d571224" xlink:to="loc_amgn_OtherCurrentNoncurrentAssetsMember_2fcd3d93-23df-4b74-a86c-1dfb6221e3cf" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember_f79e79be-7058-4fa7-93f3-1a0fac7486d0" xlink:href="amgn-20210930.xsd#amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_c3f21ea3-c4b5-4b4f-9f6f-01154d571224" xlink:to="loc_amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember_f79e79be-7058-4fa7-93f3-1a0fac7486d0" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCurrentAssetsMember_5345e317-75b5-4087-9e4f-ce26f98c4817" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherCurrentAssetsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_c3f21ea3-c4b5-4b4f-9f6f-01154d571224" xlink:to="loc_us-gaap_OtherCurrentAssetsMember_5345e317-75b5-4087-9e4f-ce26f98c4817" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesMember_81b3234b-91b1-4de0-b5ba-ca925c170127" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccruedLiabilitiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_c3f21ea3-c4b5-4b4f-9f6f-01154d571224" xlink:to="loc_us-gaap_AccruedLiabilitiesMember_81b3234b-91b1-4de0-b5ba-ca925c170127" xlink:type="arc" order="3"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/ContingenciesandcommitmentsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#ContingenciesandcommitmentsDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/ContingenciesandcommitmentsDetails" xlink:type="extended" id="i9360fa65b4034bcab8a17b336d3e94bd_ContingenciesandcommitmentsDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingenciesLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LitigationSettlementDamagesSoughtValue_eb1d60ed-2b69-490e-922a-135cb61ed010" xlink:href="amgn-20210930.xsd#amgn_LitigationSettlementDamagesSoughtValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_amgn_LitigationSettlementDamagesSoughtValue_eb1d60ed-2b69-490e-922a-135cb61ed010" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_be3aec0f-401d-4ded-bbd4-c0ea71bc9dc5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LitigationSettlementAmountAwardedFromOtherParty"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_be3aec0f-401d-4ded-bbd4-c0ea71bc9dc5" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_e9c7af8c-5152-4b12-a75d-8765752f279d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyPatentsAllegedlyInfringedNumber"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_e9c7af8c-5152-4b12-a75d-8765752f279d" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LossContingencyNumberOfLawsuits_8806d0cc-1c98-4115-85eb-7f16f197b724" xlink:href="amgn-20210930.xsd#amgn_LossContingencyNumberOfLawsuits"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_amgn_LossContingencyNumberOfLawsuits_8806d0cc-1c98-4115-85eb-7f16f197b724" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNumberOfPlaintiffs_1b1e7e90-06f8-4ff0-951d-756686808450" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyNumberOfPlaintiffs"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_LossContingencyNumberOfPlaintiffs_1b1e7e90-06f8-4ff0-951d-756686808450" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LossContingencyPatentsExpiredNumber_1302fcaf-dbdc-4ed2-9275-77d77d9d6586" xlink:href="amgn-20210930.xsd#amgn_LossContingencyPatentsExpiredNumber"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_amgn_LossContingencyPatentsExpiredNumber_1302fcaf-dbdc-4ed2-9275-77d77d9d6586" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LossContingencyAppealPeriod_38840a1f-2a56-4ab9-b07b-5784b6ba6a4c" xlink:href="amgn-20210930.xsd#amgn_LossContingencyAppealPeriod"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_amgn_LossContingencyAppealPeriod_38840a1f-2a56-4ab9-b07b-5784b6ba6a4c" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_NumberOfAssertedPatents_270f5332-07da-479e-8e9f-ea1bb92218a8" xlink:href="amgn-20210930.xsd#amgn_NumberOfAssertedPatents"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_amgn_NumberOfAssertedPatents_270f5332-07da-479e-8e9f-ea1bb92218a8" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LitigationSettlementExpense_6c909a14-d844-4ac1-849a-8a37f0b50d90" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LitigationSettlementExpense"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_LitigationSettlementExpense_6c909a14-d844-4ac1-849a-8a37f0b50d90" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyClaimsSettledNumber_d4ac59f4-c89c-49d7-8b93-a17fb78341f2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyClaimsSettledNumber"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_LossContingencyClaimsSettledNumber_d4ac59f4-c89c-49d7-8b93-a17fb78341f2" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainContingencyPatentsFoundInfringedUponNumber_a1469445-9c25-414c-8f63-a3d3e88a7f50" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GainContingencyPatentsFoundInfringedUponNumber"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_GainContingencyPatentsFoundInfringedUponNumber_a1469445-9c25-414c-8f63-a3d3e88a7f50" xlink:type="arc" order="10"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyPendingClaimsNumber_4686f662-772a-4e27-857d-4f152f4ef2c8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyPendingClaimsNumber"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_LossContingencyPendingClaimsNumber_4686f662-772a-4e27-857d-4f152f4ef2c8" xlink:type="arc" order="11"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesTable_ee42aa44-9c60-40cc-afa7-6e02658afafb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingenciesTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_LossContingenciesTable_ee42aa44-9c60-40cc-afa7-6e02658afafb" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_d371d030-e321-4c53-8e79-32519dffd45e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_LossContingenciesTable_ee42aa44-9c60-40cc-afa7-6e02658afafb" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_d371d030-e321-4c53-8e79-32519dffd45e" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_d371d030-e321-4c53-8e79-32519dffd45e_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_d371d030-e321-4c53-8e79-32519dffd45e" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_d371d030-e321-4c53-8e79-32519dffd45e_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_6e130849-f5ea-431b-bc8e-15356ccaf066" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_d371d030-e321-4c53-8e79-32519dffd45e" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_6e130849-f5ea-431b-bc8e-15356ccaf066" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_95ab7892-e80c-42fe-bfb8-542c38078632" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_6e130849-f5ea-431b-bc8e-15356ccaf066" xlink:to="loc_us-gaap_SubsequentEventMember_95ab7892-e80c-42fe-bfb8-542c38078632" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_8db50c94-e050-485e-bb4a-c07b58c439f4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingenciesByNatureOfContingencyAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_LossContingenciesTable_ee42aa44-9c60-40cc-afa7-6e02658afafb" xlink:to="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_8db50c94-e050-485e-bb4a-c07b58c439f4" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNatureDomain_8db50c94-e050-485e-bb4a-c07b58c439f4_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyNatureDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_8db50c94-e050-485e-bb4a-c07b58c439f4" xlink:to="loc_us-gaap_LossContingencyNatureDomain_8db50c94-e050-485e-bb4a-c07b58c439f4_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNatureDomain_912b80c5-f549-4128-9a34-5342beb50974" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyNatureDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_8db50c94-e050-485e-bb4a-c07b58c439f4" xlink:to="loc_us-gaap_LossContingencyNatureDomain_912b80c5-f549-4128-9a34-5342beb50974" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_PatentTrialAndAppealBoardPatentChallengesMember_0ec2c49c-6196-4b03-abcb-6f32c8c272db" xlink:href="amgn-20210930.xsd#amgn_PatentTrialAndAppealBoardPatentChallengesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingencyNatureDomain_912b80c5-f549-4128-9a34-5342beb50974" xlink:to="loc_amgn_PatentTrialAndAppealBoardPatentChallengesMember_0ec2c49c-6196-4b03-abcb-6f32c8c272db" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseAxis_1bfe297b-f9c7-461b-ba70-721ec4d3cddc" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_LitigationCaseAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_LossContingenciesTable_ee42aa44-9c60-40cc-afa7-6e02658afafb" xlink:to="loc_srt_LitigationCaseAxis_1bfe297b-f9c7-461b-ba70-721ec4d3cddc" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseTypeDomain_1bfe297b-f9c7-461b-ba70-721ec4d3cddc_default" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_LitigationCaseTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_LitigationCaseAxis_1bfe297b-f9c7-461b-ba70-721ec4d3cddc" xlink:to="loc_srt_LitigationCaseTypeDomain_1bfe297b-f9c7-461b-ba70-721ec4d3cddc_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_LitigationCaseTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_LitigationCaseAxis_1bfe297b-f9c7-461b-ba70-721ec4d3cddc" xlink:to="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_HospiraMember_4d48f517-f85e-4d17-9504-b98a77d9abb0" xlink:href="amgn-20210930.xsd#amgn_HospiraMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_HospiraMember_4d48f517-f85e-4d17-9504-b98a77d9abb0" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_KANJINTIPatentLitigationMember_2d64f659-d1cd-4367-81c5-c30d76363002" xlink:href="amgn-20210930.xsd#amgn_KANJINTIPatentLitigationMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_KANJINTIPatentLitigationMember_2d64f659-d1cd-4367-81c5-c30d76363002" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_HumiraBiosimilarAntitrustClassActionsMember_78879f3e-a4d2-46cc-a3fb-537aded09293" xlink:href="amgn-20210930.xsd#amgn_HumiraBiosimilarAntitrustClassActionsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_HumiraBiosimilarAntitrustClassActionsMember_78879f3e-a4d2-46cc-a3fb-537aded09293" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_SensiparAntitrustClassActionsMember_59969e00-7806-42c7-ba9f-2ad0e083c95b" xlink:href="amgn-20210930.xsd#amgn_SensiparAntitrustClassActionsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_SensiparAntitrustClassActionsMember_59969e00-7806-42c7-ba9f-2ad0e083c95b" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_KyprolisMember_805ef105-9264-444a-9490-4d2e84e3149d" xlink:href="amgn-20210930.xsd#amgn_KyprolisMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_KyprolisMember_805ef105-9264-444a-9490-4d2e84e3149d" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_KyprolisANDAPatentLitigationMember_b7a2ff18-a9d9-42fe-834e-af883902a7a3" xlink:href="amgn-20210930.xsd#amgn_KyprolisANDAPatentLitigationMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_KyprolisANDAPatentLitigationMember_b7a2ff18-a9d9-42fe-834e-af883902a7a3" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_NovartisPharmaAGMember_9116cfb4-2524-4261-a5db-ad368ce8eb6b" xlink:href="amgn-20210930.xsd#amgn_NovartisPharmaAGMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_NovartisPharmaAGMember_9116cfb4-2524-4261-a5db-ad368ce8eb6b" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtezlaANDAPatentLitigationMember_2893bb87-7a74-4ac5-8ce7-faa9a004f2e8" xlink:href="amgn-20210930.xsd#amgn_OtezlaANDAPatentLitigationMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_OtezlaANDAPatentLitigationMember_2893bb87-7a74-4ac5-8ce7-faa9a004f2e8" xlink:type="arc" order="7"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.amgen.com/role/SubsequenteventsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#SubsequenteventsDetails"/>
  <link:definitionLink xlink:role="http://www.amgen.com/role/SubsequenteventsDetails" xlink:type="extended" id="if8ce6f3c24604f55b00a91dbdb26211f_SubsequenteventsDetails">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventLineItems_87282682-c37c-44b3-b71d-137ddc48eb15" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_UpFrontPayment_077b74a9-97db-48e5-a904-6a37364ede6e" xlink:href="amgn-20210930.xsd#amgn_UpFrontPayment"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SubsequentEventLineItems_87282682-c37c-44b3-b71d-137ddc48eb15" xlink:to="loc_amgn_UpFrontPayment_077b74a9-97db-48e5-a904-6a37364ede6e" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions_a8c90466-1a18-45d0-a85a-760d5f88f887" xlink:href="amgn-20210930.xsd#amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SubsequentEventLineItems_87282682-c37c-44b3-b71d-137ddc48eb15" xlink:to="loc_amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions_a8c90466-1a18-45d0-a85a-760d5f88f887" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesGross_87661944-6032-4367-a335-9cc94e5e345d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesGross"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SubsequentEventLineItems_87282682-c37c-44b3-b71d-137ddc48eb15" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesGross_87661944-6032-4367-a335-9cc94e5e345d" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_bd7e3a65-12e4-4e20-88bc-f18d442e9eb8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SubsequentEventLineItems_87282682-c37c-44b3-b71d-137ddc48eb15" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_bd7e3a65-12e4-4e20-88bc-f18d442e9eb8" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTable_08933f88-cec4-48ff-a3d1-bcbb7cfe09c0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_SubsequentEventLineItems_87282682-c37c-44b3-b71d-137ddc48eb15" xlink:to="loc_us-gaap_SubsequentEventTable_08933f88-cec4-48ff-a3d1-bcbb7cfe09c0" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementScenarioAxis_c92011cd-558e-4244-b000-27f5465a8c0b" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_StatementScenarioAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_SubsequentEventTable_08933f88-cec4-48ff-a3d1-bcbb7cfe09c0" xlink:to="loc_srt_StatementScenarioAxis_c92011cd-558e-4244-b000-27f5465a8c0b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain_c92011cd-558e-4244-b000-27f5465a8c0b_default" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ScenarioUnspecifiedDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_StatementScenarioAxis_c92011cd-558e-4244-b000-27f5465a8c0b" xlink:to="loc_srt_ScenarioUnspecifiedDomain_c92011cd-558e-4244-b000-27f5465a8c0b_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain_2714fb9a-1360-43dd-9ef1-03343c67c686" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ScenarioUnspecifiedDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_StatementScenarioAxis_c92011cd-558e-4244-b000-27f5465a8c0b" xlink:to="loc_srt_ScenarioUnspecifiedDomain_2714fb9a-1360-43dd-9ef1-03343c67c686" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioForecastMember_37c7ed8f-be12-42ef-a852-4d7e34d224f8" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ScenarioForecastMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ScenarioUnspecifiedDomain_2714fb9a-1360-43dd-9ef1-03343c67c686" xlink:to="loc_srt_ScenarioForecastMember_37c7ed8f-be12-42ef-a852-4d7e34d224f8" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_baccf25a-f8e0-4276-8636-81f1fbabb1ab" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_SubsequentEventTable_08933f88-cec4-48ff-a3d1-bcbb7cfe09c0" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_baccf25a-f8e0-4276-8636-81f1fbabb1ab" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_baccf25a-f8e0-4276-8636-81f1fbabb1ab_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_baccf25a-f8e0-4276-8636-81f1fbabb1ab" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_baccf25a-f8e0-4276-8636-81f1fbabb1ab_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_9d324147-144f-4d15-b7e3-f11219a14c38" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_baccf25a-f8e0-4276-8636-81f1fbabb1ab" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_9d324147-144f-4d15-b7e3-f11219a14c38" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TeneobioIncMember_ce22d6ff-6b93-4829-a631-7255d16b183a" xlink:href="amgn-20210930.xsd#amgn_TeneobioIncMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_9d324147-144f-4d15-b7e3-f11219a14c38" xlink:to="loc_amgn_TeneobioIncMember_ce22d6ff-6b93-4829-a631-7255d16b183a" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_b1a4ae76-de6d-4b45-947e-387259aa3f2a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_SubsequentEventTable_08933f88-cec4-48ff-a3d1-bcbb7cfe09c0" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_b1a4ae76-de6d-4b45-947e-387259aa3f2a" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_b1a4ae76-de6d-4b45-947e-387259aa3f2a_default" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_b1a4ae76-de6d-4b45-947e-387259aa3f2a" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_b1a4ae76-de6d-4b45-947e-387259aa3f2a_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_624b7d05-51ef-4399-8955-dd70b8916629" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_b1a4ae76-de6d-4b45-947e-387259aa3f2a" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_624b7d05-51ef-4399-8955-dd70b8916629" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_fca423df-7fa1-4ea2-8c08-3c8e9ee582c4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_624b7d05-51ef-4399-8955-dd70b8916629" xlink:to="loc_us-gaap_SubsequentEventMember_fca423df-7fa1-4ea2-8c08-3c8e9ee582c4" xlink:type="arc" order="0"/>
  </link:definitionLink>
</link:linkbase>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.LAB
<SEQUENCE>8
<FILENAME>amgn-20210930_lab.xml
<DESCRIPTION>XBRL TAXONOMY EXTENSION LABEL LINKBASE DOCUMENT
<TEXT>
<XBRL>
<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2021 Workiva-->
<!--r:e5235af6-2e2c-44cc-b741-bc0b6d42fa8f,g:5c86b37c-c57f-4c71-acc2-468d6efa37c1-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodStartLabel"/>
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/netLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel"/>
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel"/>
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel"/>
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodEndLabel"/>
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel"/>
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel"/>
  <link:labelLink xlink:role="http://www.xbrl.org/2003/role/link" xlink:type="extended">
    <link:label id="lab_us-gaap_EquityMethodInvestmentQuotedMarketValue_2a016f4c-9bcd-475f-b636-af182b7fe07a_terseLabel_en-US" xlink:label="lab_us-gaap_EquityMethodInvestmentQuotedMarketValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investments,Quoted Market Price</link:label>
    <link:label id="lab_us-gaap_EquityMethodInvestmentQuotedMarketValue_label_en-US" xlink:label="lab_us-gaap_EquityMethodInvestmentQuotedMarketValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investment, Quoted Market Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentQuotedMarketValue" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentQuotedMarketValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EquityMethodInvestmentQuotedMarketValue" xlink:to="lab_us-gaap_EquityMethodInvestmentQuotedMarketValue" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets_c8a16c38-5002-4b5c-a839-6e41b10d0f00_terseLabel_en-US" xlink:label="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Combination Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Assets</link:label>
    <link:label id="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets_label_en-US" xlink:label="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Combination Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Assets</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets" xlink:to="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_HedgingDesignationDomain_cbd9211a-d838-4767-b46e-ddc773a76f66_terseLabel_en-US" xlink:label="lab_us-gaap_HedgingDesignationDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedging Designation [Domain]</link:label>
    <link:label id="lab_us-gaap_HedgingDesignationDomain_label_en-US" xlink:label="lab_us-gaap_HedgingDesignationDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedging Designation [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingDesignationDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_HedgingDesignationDomain" xlink:to="lab_us-gaap_HedgingDesignationDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockRepurchaseProgramAuthorizedAmount1_3761bd98-a530-42d8-b02d-054f32b50082_terseLabel_en-US" xlink:label="lab_us-gaap_StockRepurchaseProgramAuthorizedAmount1" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock repurchase program, additional authorized amount</link:label>
    <link:label id="lab_us-gaap_StockRepurchaseProgramAuthorizedAmount1_label_en-US" xlink:label="lab_us-gaap_StockRepurchaseProgramAuthorizedAmount1" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock Repurchase Program, Authorized Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramAuthorizedAmount1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchaseProgramAuthorizedAmount1"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockRepurchaseProgramAuthorizedAmount1" xlink:to="lab_us-gaap_StockRepurchaseProgramAuthorizedAmount1" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember_323229e3-3ef8-4596-aa74-2a0f723356bb_verboseLabel_en-US" xlink:label="lab_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Available-for-sale securities [Member]</link:label>
    <link:label id="lab_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember_label_en-US" xlink:label="lab_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">AOCI, Accumulated Gain (Loss), Debt Securities, Available-for-sale, Parent [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember" xlink:to="lab_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax_ef5fc7a3-2285-4f57-827f-01e9ef996aa5_terseLabel_en-US" xlink:label="lab_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other</link:label>
    <link:label id="lab_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax_label_en-US" xlink:label="lab_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Comprehensive Income (Loss), Other Adjustment, before Tax</link:label>
    <link:label id="lab_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax_documentation_en-US" xlink:label="lab_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Comprehensive Income (Loss), Other Adjustment, before Tax</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax" xlink:href="amgn-20210930.xsd#amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax" xlink:to="lab_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_ac316b25-6456-4b87-870c-ee09ad10b5a9_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Hierarchy and NAV [Domain]</link:label>
    <link:label id="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_label_en-US" xlink:label="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Hierarchy and NAV [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:to="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NetIncomeLoss_1de2f47b-6674-45cf-9006-665fc16af0d2_verboseLabel_en-US" xlink:label="lab_us-gaap_NetIncomeLoss" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net income</link:label>
    <link:label id="lab_us-gaap_NetIncomeLoss_882873e6-f630-4227-b828-ab513318e311_totalLabel_en-US" xlink:label="lab_us-gaap_NetIncomeLoss" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net income</link:label>
    <link:label id="lab_us-gaap_NetIncomeLoss_a216c02b-b996-48ae-bb4a-e8ca63f80bcb_terseLabel_en-US" xlink:label="lab_us-gaap_NetIncomeLoss" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net income for basic and diluted EPS</link:label>
    <link:label id="lab_us-gaap_NetIncomeLoss_fa5af057-622b-43f2-bd11-d4a4122bd6e6_netLabel_en-US" xlink:label="lab_us-gaap_NetIncomeLoss" xlink:role="http://www.xbrl.org/2009/role/netLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net income</link:label>
    <link:label id="lab_us-gaap_NetIncomeLoss_label_en-US" xlink:label="lab_us-gaap_NetIncomeLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Income (Loss) Attributable to Parent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NetIncomeLoss" xlink:to="lab_us-gaap_NetIncomeLoss" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityEmergingGrowthCompany_61d49c60-418a-47f7-a337-299526437b72_terseLabel_en-US" xlink:label="lab_dei_EntityEmergingGrowthCompany" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Emerging Growth Company</link:label>
    <link:label id="lab_dei_EntityEmergingGrowthCompany_label_en-US" xlink:label="lab_dei_EntityEmergingGrowthCompany" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Emerging Growth Company</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityEmergingGrowthCompany" xlink:to="lab_dei_EntityEmergingGrowthCompany" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet_b357ba85-62eb-43d8-9935-45090c668a74_terseLabel_en-US" xlink:label="lab_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tax impact related to employee stock-based compensation expense</link:label>
    <link:label id="lab_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet_label_en-US" xlink:label="lab_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Adjustment to Additional Paid in Capital, Income Tax Effect from Share-based Compensation, Net</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" xlink:to="lab_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_5a83ffa0-72f0-425a-bfcc-fafeefa0a068_verboseLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Marketable securities</link:label>
    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_label_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale, Current</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent" xlink:to="lab_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncomeStatementLocationAxis_df1142ad-c631-4b5a-a651-0faf7a798899_terseLabel_en-US" xlink:label="lab_us-gaap_IncomeStatementLocationAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income Statement Location [Axis]</link:label>
    <link:label id="lab_us-gaap_IncomeStatementLocationAxis_label_en-US" xlink:label="lab_us-gaap_IncomeStatementLocationAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income Statement Location [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncomeStatementLocationAxis" xlink:to="lab_us-gaap_IncomeStatementLocationAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_4713213f-1d1e-421a-8bd9-be97e647ff7c_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated amortization</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Assets, Accumulated Amortization</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_RangeMember_01908a41-5ba1-4756-9ce4-bdfb5da796fa_terseLabel_en-US" xlink:label="lab_srt_RangeMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statistical Measurement [Domain]</link:label>
    <link:label id="lab_srt_RangeMember_label_en-US" xlink:label="lab_srt_RangeMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statistical Measurement [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_RangeMember" xlink:to="lab_srt_RangeMember" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityAddressAddressLine1_d8f965a5-1de9-425b-9e49-50ea0efa65d4_terseLabel_en-US" xlink:label="lab_dei_EntityAddressAddressLine1" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Address, Address Line One</link:label>
    <link:label id="lab_dei_EntityAddressAddressLine1_label_en-US" xlink:label="lab_dei_EntityAddressAddressLine1" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Address, Address Line One</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressAddressLine1"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityAddressAddressLine1" xlink:to="lab_dei_EntityAddressAddressLine1" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_LongTermDebtCurrentMaturitiesMember_1a086bbc-3761-4812-85b1-bafe01a56af1_terseLabel_en-US" xlink:label="lab_amgn_LongTermDebtCurrentMaturitiesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current portion of long-term debt [Member]</link:label>
    <link:label id="lab_amgn_LongTermDebtCurrentMaturitiesMember_label_en-US" xlink:label="lab_amgn_LongTermDebtCurrentMaturitiesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-Term Debt, Current Maturities [Member]</link:label>
    <link:label id="lab_amgn_LongTermDebtCurrentMaturitiesMember_documentation_en-US" xlink:label="lab_amgn_LongTermDebtCurrentMaturitiesMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-Term Debt, Current Maturities [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LongTermDebtCurrentMaturitiesMember" xlink:href="amgn-20210930.xsd#amgn_LongTermDebtCurrentMaturitiesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_LongTermDebtCurrentMaturitiesMember" xlink:to="lab_amgn_LongTermDebtCurrentMaturitiesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ThreePointThreeSevenFivePercentNotesDue2050Member_330f3d8e-a5a3-4015-9bd4-5c1449a4e22a_terseLabel_en-US" xlink:label="lab_amgn_ThreePointThreeSevenFivePercentNotesDue2050Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">3.375% notes due 2050 (3.375% 2050 Notes) [Member]</link:label>
    <link:label id="lab_amgn_ThreePointThreeSevenFivePercentNotesDue2050Member_label_en-US" xlink:label="lab_amgn_ThreePointThreeSevenFivePercentNotesDue2050Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point Three Seven Five Percent Notes Due 2050 [Member]</link:label>
    <link:label id="lab_amgn_ThreePointThreeSevenFivePercentNotesDue2050Member_documentation_en-US" xlink:label="lab_amgn_ThreePointThreeSevenFivePercentNotesDue2050Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point Three Seven Five Percent Notes Due 2050 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointThreeSevenFivePercentNotesDue2050Member" xlink:href="amgn-20210930.xsd#amgn_ThreePointThreeSevenFivePercentNotesDue2050Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ThreePointThreeSevenFivePercentNotesDue2050Member" xlink:to="lab_amgn_ThreePointThreeSevenFivePercentNotesDue2050Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DividendsCommonStockCash_234ad918-ef57-4de0-8a1a-735aa4632966_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_DividendsCommonStockCash" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Dividends declared on common stock</link:label>
    <link:label id="lab_us-gaap_DividendsCommonStockCash_label_en-US" xlink:label="lab_us-gaap_DividendsCommonStockCash" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Dividends, Common Stock, Cash</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DividendsCommonStockCash" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DividendsCommonStockCash"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DividendsCommonStockCash" xlink:to="lab_us-gaap_DividendsCommonStockCash" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EquitySecuritiesFvNi_81369c97-b2ad-4f6a-867c-80da39e8765e_terseLabel_en-US" xlink:label="lab_us-gaap_EquitySecuritiesFvNi" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity securities</link:label>
    <link:label id="lab_us-gaap_EquitySecuritiesFvNi_label_en-US" xlink:label="lab_us-gaap_EquitySecuritiesFvNi" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Securities, FV-NI, Current</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNi" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesFvNi"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EquitySecuritiesFvNi" xlink:to="lab_us-gaap_EquitySecuritiesFvNi" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EquityMethodInvestmentsFairValueDisclosure_301d4284-ceb0-480b-b928-95eb71b1277d_terseLabel_en-US" xlink:label="lab_us-gaap_EquityMethodInvestmentsFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investments, Fair Value Disclosure</link:label>
    <link:label id="lab_us-gaap_EquityMethodInvestmentsFairValueDisclosure_label_en-US" xlink:label="lab_us-gaap_EquityMethodInvestmentsFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investments, Fair Value Disclosure</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentsFairValueDisclosure" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentsFairValueDisclosure"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EquityMethodInvestmentsFairValueDisclosure" xlink:to="lab_us-gaap_EquityMethodInvestmentsFairValueDisclosure" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions_64b3abcd-36f3-4368-aa85-c1bef5400b61_terseLabel_en-US" xlink:label="lab_amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Addition from Kirin-Amgen acquisition</link:label>
    <link:label id="lab_amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions_label_en-US" xlink:label="lab_amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Combination, Fair Value of Contingent Consideration Arrangements, Addition from Acquisitions</link:label>
    <link:label id="lab_amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions_documentation_en-US" xlink:label="lab_amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Combination, Fair Value of Contingent Consideration Arrangements, Addition from Acquisitions</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions" xlink:href="amgn-20210930.xsd#amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions" xlink:to="lab_amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_RevenueFromContractWithCustomerAbstract_5323a788-0c50-485e-9434-7e77b46b3815_terseLabel_en-US" xlink:label="lab_us-gaap_RevenueFromContractWithCustomerAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Revenue from Contract with Customer [Abstract]</link:label>
    <link:label id="lab_us-gaap_RevenueFromContractWithCustomerAbstract_label_en-US" xlink:label="lab_us-gaap_RevenueFromContractWithCustomerAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Revenue from Contract with Customer [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract" xlink:to="lab_us-gaap_RevenueFromContractWithCustomerAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract_775a7885-ab1e-4387-a1cb-393a55183290_verboseLabel_en-US" xlink:label="lab_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair values of both derivatives designated as hedging instruments and not designated as hedging instruments included in Condensed Consolidated Balance Sheets</link:label>
    <link:label id="lab_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract_label_en-US" xlink:label="lab_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Values Of Both Derivatives Designated As Hedging Instruments And Not Designated As Hedging Instruments Included In Condensed Consolidated Balance Sheets [Abstract]</link:label>
    <link:label id="lab_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract_documentation_en-US" xlink:label="lab_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Values Of Both Derivatives Designated As Hedging Instruments And Not Designated As Hedging Instruments Included In Condensed Consolidated Balance Sheets.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract" xlink:href="amgn-20210930.xsd#amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract" xlink:to="lab_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityFilerCategory_ee2a9e17-1830-4f88-bc7d-0607de31a00b_terseLabel_en-US" xlink:label="lab_dei_EntityFilerCategory" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Filer Category</link:label>
    <link:label id="lab_dei_EntityFilerCategory_label_en-US" xlink:label="lab_dei_EntityFilerCategory" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Filer Category</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFilerCategory" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityFilerCategory"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityFilerCategory" xlink:to="lab_dei_EntityFilerCategory" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther_2b995796-d391-49cc-82ab-ceb783a1e15a_terseLabel_en-US" xlink:label="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Liabilities, Other</link:label>
    <link:label id="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther_label_en-US" xlink:label="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Liabilities, Other</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther" xlink:to="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommonStocksIncludingAdditionalPaidInCapital_9aa689eb-097e-4deb-974b-a93c5b403509_verboseLabel_en-US" xlink:label="lab_us-gaap_CommonStocksIncludingAdditionalPaidInCapital" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock and additional paid-in capital; $0.0001 par value; 2,750.0 shares authorized; outstanding&#8212;565.0 shares in 2021 and 578.3 shares in 2020</link:label>
    <link:label id="lab_us-gaap_CommonStocksIncludingAdditionalPaidInCapital_label_en-US" xlink:label="lab_us-gaap_CommonStocksIncludingAdditionalPaidInCapital" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common Stocks, Including Additional Paid in Capital</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStocksIncludingAdditionalPaidInCapital" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStocksIncludingAdditionalPaidInCapital"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommonStocksIncludingAdditionalPaidInCapital" xlink:to="lab_us-gaap_CommonStocksIncludingAdditionalPaidInCapital" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_2adc64f0-880a-4997-ade2-c0511cd8d1a1_terseLabel_en-US" xlink:label="lab_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Number of patents allegedly infringed upon</link:label>
    <link:label id="lab_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_label_en-US" xlink:label="lab_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, Patents Allegedly Infringed, Number</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyPatentsAllegedlyInfringedNumber"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber" xlink:to="lab_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_LitigationSettlementDamagesSoughtValue_ba4c5a87-6d0d-4d93-94de-bbbfc33ed23b_terseLabel_en-US" xlink:label="lab_amgn_LitigationSettlementDamagesSoughtValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amount awarded from settlement</link:label>
    <link:label id="lab_amgn_LitigationSettlementDamagesSoughtValue_label_en-US" xlink:label="lab_amgn_LitigationSettlementDamagesSoughtValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Litigation Settlement, Damages Sought, Value</link:label>
    <link:label id="lab_amgn_LitigationSettlementDamagesSoughtValue_documentation_en-US" xlink:label="lab_amgn_LitigationSettlementDamagesSoughtValue" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Litigation Settlement, Damages Sought, Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LitigationSettlementDamagesSoughtValue" xlink:href="amgn-20210930.xsd#amgn_LitigationSettlementDamagesSoughtValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_LitigationSettlementDamagesSoughtValue" xlink:to="lab_amgn_LitigationSettlementDamagesSoughtValue" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherAssetsNoncurrent_85f0f12a-1b02-4aad-814f-8bbc67cffe86_verboseLabel_en-US" xlink:label="lab_us-gaap_OtherAssetsNoncurrent" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other noncurrent assets</link:label>
    <link:label id="lab_us-gaap_OtherAssetsNoncurrent_label_en-US" xlink:label="lab_us-gaap_OtherAssetsNoncurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Assets, Noncurrent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherAssetsNoncurrent" xlink:to="lab_us-gaap_OtherAssetsNoncurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_HedgedLiabilityDiscontinuedFairValueHedge_947f097b-f5ea-47ca-9b68-eceebdfca424_terseLabel_en-US" xlink:label="lab_amgn_HedgedLiabilityDiscontinuedFairValueHedge" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Carrying value with discontinued hedging relationships</link:label>
    <link:label id="lab_amgn_HedgedLiabilityDiscontinuedFairValueHedge_label_en-US" xlink:label="lab_amgn_HedgedLiabilityDiscontinuedFairValueHedge" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedged Liability, Discontinued Fair Value Hedge</link:label>
    <link:label id="lab_amgn_HedgedLiabilityDiscontinuedFairValueHedge_documentation_en-US" xlink:label="lab_amgn_HedgedLiabilityDiscontinuedFairValueHedge" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedged Liability, Discontinued Fair Value Hedge</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_HedgedLiabilityDiscontinuedFairValueHedge" xlink:href="amgn-20210930.xsd#amgn_HedgedLiabilityDiscontinuedFairValueHedge"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_HedgedLiabilityDiscontinuedFairValueHedge" xlink:to="lab_amgn_HedgedLiabilityDiscontinuedFairValueHedge" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InProcessResearchAndDevelopmentMember_70bba40e-56ad-4b33-8e79-67e4439d63c7_terseLabel_en-US" xlink:label="lab_us-gaap_InProcessResearchAndDevelopmentMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">In-process Research and Development [Member]</link:label>
    <link:label id="lab_us-gaap_InProcessResearchAndDevelopmentMember_label_en-US" xlink:label="lab_us-gaap_InProcessResearchAndDevelopmentMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">In Process Research and Development [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InProcessResearchAndDevelopmentMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InProcessResearchAndDevelopmentMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InProcessResearchAndDevelopmentMember" xlink:to="lab_us-gaap_InProcessResearchAndDevelopmentMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_81e6326f-c8d3-4271-94ac-9c4cd266aaad_totalLabel_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase in cash and cash equivalents</link:label>
    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_label_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:to="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_1e96151b-0e0f-49cf-88a9-e6580a4dcf4f_terseLabel_en-US" xlink:label="lab_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock-based compensation expense</link:label>
    <link:label id="lab_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_label_en-US" xlink:label="lab_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">APIC, Share-based Payment Arrangement, Increase for Cost Recognition</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:to="lab_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable_72918558-91b4-4dcc-80e2-2bc32819e84b_verboseLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued income taxes, net</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) in Income Taxes Payable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable" xlink:to="lab_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_d8aaaa42-eff3-4ec5-bf26-9c028d66c9f6_verboseLabel_en-US" xlink:label="lab_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Foreign currency and cross-currency swap contracts</link:label>
    <link:label id="lab_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_label_en-US" xlink:label="lab_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Foreign Currency Contracts, Liability, Fair Value Disclosure</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure" xlink:to="lab_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock_11f2451b-6140-405e-99d2-2bb8a4274979_terseLabel_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amortized cost, gross unrealized gains, gross unrealized losses and estimated fair values of available-for-sale investments by type of security</link:label>
    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock_label_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock" xlink:to="lab_us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock_f3da5ad4-9ee5-4fe2-8cfe-2d1568c9378b_terseLabel_en-US" xlink:label="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassifications out of accumulated other comprehensive income</link:label>
    <link:label id="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock_label_en-US" xlink:label="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification out of Accumulated Other Comprehensive Income [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock" xlink:to="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock_26c78e58-5b7a-4ebc-bad8-92bf62e0d203_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivatives in fair value hedging relationships</link:label>
    <link:label id="lab_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Fair Value Hedging Instruments, Statements of Financial Performance and Financial Position, Location [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:to="lab_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_IdentifiableIntangibleAssetsGross_410fbc1f-4bdd-4c3e-aa0b-15cb0c82a4ec_terseLabel_en-US" xlink:label="lab_amgn_IdentifiableIntangibleAssetsGross" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Gross carrying amount</link:label>
    <link:label id="lab_amgn_IdentifiableIntangibleAssetsGross_label_en-US" xlink:label="lab_amgn_IdentifiableIntangibleAssetsGross" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Identifiable Intangible Assets Gross</link:label>
    <link:label id="lab_amgn_IdentifiableIntangibleAssetsGross_documentation_en-US" xlink:label="lab_amgn_IdentifiableIntangibleAssetsGross" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Identifiable intangible assets gross.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_IdentifiableIntangibleAssetsGross" xlink:href="amgn-20210930.xsd#amgn_IdentifiableIntangibleAssetsGross"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_IdentifiableIntangibleAssetsGross" xlink:to="lab_amgn_IdentifiableIntangibleAssetsGross" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherGeneralExpense_27948e94-fa1c-4683-a54c-c3b59f922ca6_verboseLabel_en-US" xlink:label="lab_us-gaap_OtherGeneralExpense" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other</link:label>
    <link:label id="lab_us-gaap_OtherGeneralExpense_label_en-US" xlink:label="lab_us-gaap_OtherGeneralExpense" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other General Expense</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherGeneralExpense" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherGeneralExpense"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherGeneralExpense" xlink:to="lab_us-gaap_OtherGeneralExpense" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_DocumentFiscalYearFocus_84cf21e5-5f1c-419e-9ebc-15e9c63e621c_terseLabel_en-US" xlink:label="lab_dei_DocumentFiscalYearFocus" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Fiscal Year Focus</link:label>
    <link:label id="lab_dei_DocumentFiscalYearFocus_label_en-US" xlink:label="lab_dei_DocumentFiscalYearFocus" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Fiscal Year Focus</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalYearFocus" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentFiscalYearFocus"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_DocumentFiscalYearFocus" xlink:to="lab_dei_DocumentFiscalYearFocus" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SubsequentEventTypeDomain_167cc9ec-fc1e-47ef-b829-c58a73856e1a_terseLabel_en-US" xlink:label="lab_us-gaap_SubsequentEventTypeDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Subsequent Event Type [Domain]</link:label>
    <link:label id="lab_us-gaap_SubsequentEventTypeDomain_label_en-US" xlink:label="lab_us-gaap_SubsequentEventTypeDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Subsequent Event Type [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SubsequentEventTypeDomain" xlink:to="lab_us-gaap_SubsequentEventTypeDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LitigationSettlementExpense_d9b1ee44-57a1-4b45-9e40-5678f8a467b5_terseLabel_en-US" xlink:label="lab_us-gaap_LitigationSettlementExpense" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Litigation Settlement, Expense</link:label>
    <link:label id="lab_us-gaap_LitigationSettlementExpense_label_en-US" xlink:label="lab_us-gaap_LitigationSettlementExpense" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Litigation Settlement, Expense</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LitigationSettlementExpense" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LitigationSettlementExpense"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LitigationSettlementExpense" xlink:to="lab_us-gaap_LitigationSettlementExpense" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_e4e718e9-88e8-4b9b-982c-eb2da45b3dde_terseLabel_en-US" xlink:label="lab_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Organization, Consolidation and Presentation of Financial Statements [Abstract]</link:label>
    <link:label id="lab_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_label_en-US" xlink:label="lab_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Organization, Consolidation and Presentation of Financial Statements [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:to="lab_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_80d011df-12e2-4b1b-82ac-a0b81b110b25_terseLabel_en-US" xlink:label="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Liabilities</link:label>
    <link:label id="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_label_en-US" xlink:label="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Liabilities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities" xlink:to="lab_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FivePointSixFivePercentNotesDue2042Member_1f2fe0ce-84d6-430d-b995-5b8e6575809e_terseLabel_en-US" xlink:label="lab_amgn_FivePointSixFivePercentNotesDue2042Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">5.65% notes due 2042 (5.65% 2042 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FivePointSixFivePercentNotesDue2042Member_label_en-US" xlink:label="lab_amgn_FivePointSixFivePercentNotesDue2042Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Five Point Six Five Percent Notes Due 2042 [Member]</link:label>
    <link:label id="lab_amgn_FivePointSixFivePercentNotesDue2042Member_documentation_en-US" xlink:label="lab_amgn_FivePointSixFivePercentNotesDue2042Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Five Point Six Five Percent Notes Due 2042 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointSixFivePercentNotesDue2042Member" xlink:href="amgn-20210930.xsd#amgn_FivePointSixFivePercentNotesDue2042Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FivePointSixFivePercentNotesDue2042Member" xlink:to="lab_amgn_FivePointSixFivePercentNotesDue2042Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AmortizationOfIntangibleAssets_f7f72803-5ac8-4236-a008-2ca55227b9d1_terseLabel_en-US" xlink:label="lab_us-gaap_AmortizationOfIntangibleAssets" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amortization charges associated with finite-lived intangible assets</link:label>
    <link:label id="lab_us-gaap_AmortizationOfIntangibleAssets_label_en-US" xlink:label="lab_us-gaap_AmortizationOfIntangibleAssets" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amortization of Intangible Assets</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AmortizationOfIntangibleAssets" xlink:to="lab_us-gaap_AmortizationOfIntangibleAssets" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_255c4cd1-ab88-424a-ad74-a52fb69f8315_verboseLabel_en-US" xlink:label="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amount available for stock repurchases under a board approved stock repurchase plan</link:label>
    <link:label id="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_label_en-US" xlink:label="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock Repurchase Program, Remaining Authorized Repurchase Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1" xlink:to="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherCurrentAssetsMember_f2b04124-ac38-4a2a-97f8-cc0e113758aa_terseLabel_en-US" xlink:label="lab_us-gaap_OtherCurrentAssetsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other current assets [Member]</link:label>
    <link:label id="lab_us-gaap_OtherCurrentAssetsMember_label_en-US" xlink:label="lab_us-gaap_OtherCurrentAssetsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Current Assets [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCurrentAssetsMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherCurrentAssetsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherCurrentAssetsMember" xlink:to="lab_us-gaap_OtherCurrentAssetsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FourPointNineFivePercentNotesDue2041Member_ea21fb79-ed53-42ab-b034-924d223199c5_terseLabel_en-US" xlink:label="lab_amgn_FourPointNineFivePercentNotesDue2041Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">4.95% notes due 2041 (4.95% 2041 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPointNineFivePercentNotesDue2041Member_label_en-US" xlink:label="lab_amgn_FourPointNineFivePercentNotesDue2041Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Four Point Nine Five Percent Notes Due 2041 [Member]</link:label>
    <link:label id="lab_amgn_FourPointNineFivePercentNotesDue2041Member_documentation_en-US" xlink:label="lab_amgn_FourPointNineFivePercentNotesDue2041Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Four Point Nine Five Percent Notes Due 2041 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointNineFivePercentNotesDue2041Member" xlink:href="amgn-20210930.xsd#amgn_FourPointNineFivePercentNotesDue2041Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPointNineFivePercentNotesDue2041Member" xlink:to="lab_amgn_FourPointNineFivePercentNotesDue2041Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_6728a41b-2a0d-45fa-99b7-f829da3047b2_verboseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfInventoryCurrentTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Inventories</link:label>
    <link:label id="lab_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfInventoryCurrentTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Inventory, Current [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfInventoryCurrentTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock" xlink:to="lab_us-gaap_ScheduleOfInventoryCurrentTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_PartnershipInterestMember_98b5b86b-e94e-4a72-9817-338e0b900f76_terseLabel_en-US" xlink:label="lab_srt_PartnershipInterestMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Limited Partnership [Member]</link:label>
    <link:label id="lab_srt_PartnershipInterestMember_label_en-US" xlink:label="lab_srt_PartnershipInterestMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Partnership Interest [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_PartnershipInterestMember" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_PartnershipInterestMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_PartnershipInterestMember" xlink:to="lab_srt_PartnershipInterestMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ResearchAndDevelopmentExpenseMember_e6036747-34db-40cc-93e2-7fea53c7f20b_terseLabel_en-US" xlink:label="lab_us-gaap_ResearchAndDevelopmentExpenseMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Research and Development Expense [Member]</link:label>
    <link:label id="lab_us-gaap_ResearchAndDevelopmentExpenseMember_label_en-US" xlink:label="lab_us-gaap_ResearchAndDevelopmentExpenseMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Research and Development Expense [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ResearchAndDevelopmentExpenseMember" xlink:to="lab_us-gaap_ResearchAndDevelopmentExpenseMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ThreePointFourFivePercentNotesDue2020Member_b79225c8-3b6e-403d-969c-2d1a43f860e5_terseLabel_en-US" xlink:label="lab_amgn_ThreePointFourFivePercentNotesDue2020Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">3.45% notes due 2020 (3.45% 2020 Notes) [Member]</link:label>
    <link:label id="lab_amgn_ThreePointFourFivePercentNotesDue2020Member_label_en-US" xlink:label="lab_amgn_ThreePointFourFivePercentNotesDue2020Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point Four Five Percent Notes Due 2020 [Member]</link:label>
    <link:label id="lab_amgn_ThreePointFourFivePercentNotesDue2020Member_documentation_en-US" xlink:label="lab_amgn_ThreePointFourFivePercentNotesDue2020Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point Four Five Percent Notes Due 2020 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointFourFivePercentNotesDue2020Member" xlink:href="amgn-20210930.xsd#amgn_ThreePointFourFivePercentNotesDue2020Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ThreePointFourFivePercentNotesDue2020Member" xlink:to="lab_amgn_ThreePointFourFivePercentNotesDue2020Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease_d9a3b11f-48c5-47a7-81e8-b04429428557_verboseLabel_en-US" xlink:label="lab_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair value adjustments</link:label>
    <link:label id="lab_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease_c582c757-0437-4c8b-8a0d-380c34f9d432_terseLabel_en-US" xlink:label="lab_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cumulative amounts of fair value hedging adjustments related to the carrying amounts of the hedged liabilities</link:label>
    <link:label id="lab_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease_label_en-US" xlink:label="lab_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedged Liability, Fair Value Hedge, Cumulative Increase (Decrease)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease" xlink:to="lab_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueByLiabilityClassAxis_e1766759-0b46-4cdd-9243-f45e8181acf1_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueByLiabilityClassAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liability Class [Axis]</link:label>
    <link:label id="lab_us-gaap_FairValueByLiabilityClassAxis_label_en-US" xlink:label="lab_us-gaap_FairValueByLiabilityClassAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liability Class [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByLiabilityClassAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByLiabilityClassAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis" xlink:to="lab_us-gaap_FairValueByLiabilityClassAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SubsequentEventsAbstract_label_en-US" xlink:label="lab_us-gaap_SubsequentEventsAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Subsequent Events [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventsAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SubsequentEventsAbstract" xlink:to="lab_us-gaap_SubsequentEventsAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_BusinessCombinationAndAssetAcquisitionAbstract_label_en-US" xlink:label="lab_us-gaap_BusinessCombinationAndAssetAcquisitionAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Combination and Asset Acquisition [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationAndAssetAcquisitionAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationAndAssetAcquisitionAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BusinessCombinationAndAssetAcquisitionAbstract" xlink:to="lab_us-gaap_BusinessCombinationAndAssetAcquisitionAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_HedgedLiabilityFairValueHedge_c3723bcf-7e13-4db0-8f83-c02835b8a30b_terseLabel_en-US" xlink:label="lab_us-gaap_HedgedLiabilityFairValueHedge" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedged Liability, Fair Value Hedge</link:label>
    <link:label id="lab_us-gaap_HedgedLiabilityFairValueHedge_label_en-US" xlink:label="lab_us-gaap_HedgedLiabilityFairValueHedge" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedged Liability, Fair Value Hedge</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgedLiabilityFairValueHedge" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgedLiabilityFairValueHedge"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_HedgedLiabilityFairValueHedge" xlink:to="lab_us-gaap_HedgedLiabilityFairValueHedge" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_6372d76b-2b89-4c35-b422-35d28526d922_terseLabel_en-US" xlink:label="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">5.50% &#163;475 million notes due 2026 (5.50% 2026 pound sterling Notes) [Member]</link:label>
    <link:label id="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_1215c296-4720-481d-9e59-7759d36fe40a_verboseLabel_en-US" xlink:label="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">5.50% 2026 pound sterling Notes [Member]</link:label>
    <link:label id="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_label_en-US" xlink:label="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Five Point Five Zero Percent Pound Sterling Notes Due 2026 [Member]</link:label>
    <link:label id="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_documentation_en-US" xlink:label="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Five Point Five Zero Percent Pound Sterling Notes Due 2026 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member" xlink:href="amgn-20210930.xsd#amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member" xlink:to="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_BusinessAcquisitionAxis_08b40953-f858-4da2-b07e-39153cf81ae5_terseLabel_en-US" xlink:label="lab_us-gaap_BusinessAcquisitionAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Acquisition [Axis]</link:label>
    <link:label id="lab_us-gaap_BusinessAcquisitionAxis_label_en-US" xlink:label="lab_us-gaap_BusinessAcquisitionAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Acquisition [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BusinessAcquisitionAxis" xlink:to="lab_us-gaap_BusinessAcquisitionAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_SixPointNineZeroPercentNotesDue2038Member_d0abe4ca-4baf-4a09-9adf-d62b22850177_terseLabel_en-US" xlink:label="lab_amgn_SixPointNineZeroPercentNotesDue2038Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">6.90% notes due 2038 (6.90% 2038 Notes) [Member]</link:label>
    <link:label id="lab_amgn_SixPointNineZeroPercentNotesDue2038Member_label_en-US" xlink:label="lab_amgn_SixPointNineZeroPercentNotesDue2038Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Six Point Nine Zero Percent Notes Due 2038 [Member]</link:label>
    <link:label id="lab_amgn_SixPointNineZeroPercentNotesDue2038Member_documentation_en-US" xlink:label="lab_amgn_SixPointNineZeroPercentNotesDue2038Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Six Point Nine Zero Percent Notes Due 2038 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_SixPointNineZeroPercentNotesDue2038Member" xlink:href="amgn-20210930.xsd#amgn_SixPointNineZeroPercentNotesDue2038Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_SixPointNineZeroPercentNotesDue2038Member" xlink:to="lab_amgn_SixPointNineZeroPercentNotesDue2038Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_9a4c2082-b193-4ff5-9823-b22f758476f4_terseLabel_en-US" xlink:label="lab_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Revenue from External Customer [Line Items]</link:label>
    <link:label id="lab_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_label_en-US" xlink:label="lab_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Revenue from External Customer [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems" xlink:to="lab_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CashFlowHedgingMember_b22d3e71-1cac-4d8c-a6e3-32bc09c3a234_verboseLabel_en-US" xlink:label="lab_us-gaap_CashFlowHedgingMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash flow hedges [Member]</link:label>
    <link:label id="lab_us-gaap_CashFlowHedgingMember_5f726a0b-e5f7-4f93-89ba-08112871ec98_terseLabel_en-US" xlink:label="lab_us-gaap_CashFlowHedgingMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash flow hedge [Member]</link:label>
    <link:label id="lab_us-gaap_CashFlowHedgingMember_label_en-US" xlink:label="lab_us-gaap_CashFlowHedgingMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash Flow Hedging [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgingMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashFlowHedgingMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CashFlowHedgingMember" xlink:to="lab_us-gaap_CashFlowHedgingMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease_833de1e1-8a2b-4d27-a6b2-d1edc4a61e15_terseLabel_en-US" xlink:label="lab_us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedging adjustments on discontinued hedging relationships</link:label>
    <link:label id="lab_us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease_label_en-US" xlink:label="lab_us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedged Liability, Discontinued Fair Value Hedge, Cumulative Increase (Decrease)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease" xlink:to="lab_us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeAssetFairValueNetAbstract_475d79cd-904a-407b-bd2d-716991f647d2_verboseLabel_en-US" xlink:label="lab_us-gaap_DerivativeAssetFairValueNetAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets</link:label>
    <link:label id="lab_us-gaap_DerivativeAssetFairValueNetAbstract_label_en-US" xlink:label="lab_us-gaap_DerivativeAssetFairValueNetAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Asset, Fair Value, Amount Not Offset Against Collateral [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssetFairValueNetAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeAssetFairValueNetAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeAssetFairValueNetAbstract" xlink:to="lab_us-gaap_DerivativeAssetFairValueNetAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_fa8ce721-0feb-42ff-b237-a756c7fe893d_verboseLabel_en-US" xlink:label="lab_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proceeds from maturities of marketable securities</link:label>
    <link:label id="lab_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_label_en-US" xlink:label="lab_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proceeds from Maturities, Prepayments and Calls of Debt Securities, Available-for-sale</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities" xlink:to="lab_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_XgevaMember_c7963ba0-0404-470a-8f64-f013044bb883_terseLabel_en-US" xlink:label="lab_amgn_XgevaMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">XGEVA&#174; (denosumab) [Member]</link:label>
    <link:label id="lab_amgn_XgevaMember_label_en-US" xlink:label="lab_amgn_XgevaMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">XGEVA [Member]</link:label>
    <link:label id="lab_amgn_XgevaMember_documentation_en-US" xlink:label="lab_amgn_XgevaMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">XGEVA.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_XgevaMember" xlink:href="amgn-20210930.xsd#amgn_XgevaMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_XgevaMember" xlink:to="lab_amgn_XgevaMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AssetsAbstract_1fa13605-c2eb-4a75-8747-6f6c208c4e7e_verboseLabel_en-US" xlink:label="lab_us-gaap_AssetsAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">ASSETS</link:label>
    <link:label id="lab_us-gaap_AssetsAbstract_label_en-US" xlink:label="lab_us-gaap_AssetsAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AssetsAbstract" xlink:to="lab_us-gaap_AssetsAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock_1ff52b0e-25c2-49d8-ad48-ddf1b3dc4709_verboseLabel_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative instruments</link:label>
    <link:label id="lab_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock_label_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instruments and Hedging Activities Disclosure [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock" xlink:to="lab_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock_74f53e0b-b24a-41af-bed2-c5179792c8b6_verboseLabel_en-US" xlink:label="lab_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair values of available-for-sale interest-bearing security investments by contractual maturity</link:label>
    <link:label id="lab_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock_label_en-US" xlink:label="lab_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments Classified by Contractual Maturity Date [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock" xlink:to="lab_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost_e42e5a3a-2ecb-4f88-809e-c32ba72aced9_verboseLabel_en-US" xlink:label="lab_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Research and development</link:label>
    <link:label id="lab_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost_label_en-US" xlink:label="lab_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Research and Development Expense (Excluding Acquired in Process Cost)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost" xlink:to="lab_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_73db79a0-ffd7-43ee-94a1-73662a467670_terseLabel_en-US" xlink:label="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Goodwill and other intangible assets</link:label>
    <link:label id="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_label_en-US" xlink:label="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Goodwill and Intangible Assets Disclosure [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock" xlink:to="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_3345cd2d-543a-4b2c-a8d1-b3cfe6a8bd0d_verboseLabel_en-US" xlink:label="lab_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Property, plant and equipment, net</link:label>
    <link:label id="lab_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_label_en-US" xlink:label="lab_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Property, Plant and Equipment, Policy [Policy Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PropertyPlantAndEquipmentPolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock" xlink:to="lab_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityAddressCityOrTown_2a46e07d-7005-4d73-892e-af3f22325d3d_terseLabel_en-US" xlink:label="lab_dei_EntityAddressCityOrTown" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Address, City or Town</link:label>
    <link:label id="lab_dei_EntityAddressCityOrTown_label_en-US" xlink:label="lab_dei_EntityAddressCityOrTown" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Address, City or Town</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressCityOrTown"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityAddressCityOrTown" xlink:to="lab_dei_EntityAddressCityOrTown" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_CurrencyAxis_93d2dc1f-6855-4d9d-ba4b-f38286b9e594_terseLabel_en-US" xlink:label="lab_srt_CurrencyAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Currency [Axis]</link:label>
    <link:label id="lab_srt_CurrencyAxis_label_en-US" xlink:label="lab_srt_CurrencyAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Currency [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CurrencyAxis" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CurrencyAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_CurrencyAxis" xlink:to="lab_srt_CurrencyAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_RetainedEarningsMember_8a317e3e-cdb4-4d9e-935b-5f7ec6996da1_terseLabel_en-US" xlink:label="lab_us-gaap_RetainedEarningsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated deficit [Member]</link:label>
    <link:label id="lab_us-gaap_RetainedEarningsMember_label_en-US" xlink:label="lab_us-gaap_RetainedEarningsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Retained Earnings [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_RetainedEarningsMember" xlink:to="lab_us-gaap_RetainedEarningsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtInstrumentAxis_e13e6964-ef5e-47cf-b0ba-d21605c9e40e_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument [Axis]</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentAxis_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentAxis" xlink:to="lab_us-gaap_DebtInstrumentAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock_8f52339f-7694-48cd-893a-13600c03ed47_terseLabel_en-US" xlink:label="lab_amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of long-term instruments exchanged</link:label>
    <link:label id="lab_amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock_label_en-US" xlink:label="lab_amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Long-term Debt Instruments Exchanged [Table Text Block]</link:label>
    <link:label id="lab_amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock_documentation_en-US" xlink:label="lab_amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Long-term Debt Instruments Exchanged [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock" xlink:href="amgn-20210930.xsd#amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock" xlink:to="lab_amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_c110d109-1721-4e38-ba7c-b6b06f672d0c_verboseLabel_en-US" xlink:label="lab_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Contingencies and commitments</link:label>
    <link:label id="lab_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_label_en-US" xlink:label="lab_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Commitments and Contingencies Disclosure [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:to="lab_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue_89ce5e16-a7ef-4493-9d42-05299662c304_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Repurchases of common stock</link:label>
    <link:label id="lab_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue_label_en-US" xlink:label="lab_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock Repurchased and Retired During Period, Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchasedAndRetiredDuringPeriodValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue" xlink:to="lab_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncreaseDecreaseInAccountsReceivable_bd9f58b2-a452-41f9-9c8f-6bdc33c1593e_negatedLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Trade receivables, net</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInAccountsReceivable_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) in Accounts Receivable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:to="lab_us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_MarketingRelatedIntangibleAssetsMember_276ec2ae-b401-463a-882b-4f08ddb84f5b_terseLabel_en-US" xlink:label="lab_us-gaap_MarketingRelatedIntangibleAssetsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Marketing-Related Rights [Member]</link:label>
    <link:label id="lab_us-gaap_MarketingRelatedIntangibleAssetsMember_label_en-US" xlink:label="lab_us-gaap_MarketingRelatedIntangibleAssetsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Marketing-Related Intangible Assets [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketingRelatedIntangibleAssetsMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MarketingRelatedIntangibleAssetsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_MarketingRelatedIntangibleAssetsMember" xlink:to="lab_us-gaap_MarketingRelatedIntangibleAssetsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_CrossCurrencySwapContractsMember_e97adcd0-2d2b-400a-8d6e-47c93b2aea03_netLabel_en-US" xlink:label="lab_amgn_CrossCurrencySwapContractsMember" xlink:role="http://www.xbrl.org/2009/role/netLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cross-currency swap contract [Member]</link:label>
    <link:label id="lab_amgn_CrossCurrencySwapContractsMember_8e5c99ef-b306-4721-a665-de491211e34d_terseLabel_en-US" xlink:label="lab_amgn_CrossCurrencySwapContractsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cross-currency swap contracts [Member]</link:label>
    <link:label id="lab_amgn_CrossCurrencySwapContractsMember_81cd1c65-be85-4771-936f-5d96ccd9c526_verboseLabel_en-US" xlink:label="lab_amgn_CrossCurrencySwapContractsMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cross-currency swap contracts [Member]</link:label>
    <link:label id="lab_amgn_CrossCurrencySwapContractsMember_label_en-US" xlink:label="lab_amgn_CrossCurrencySwapContractsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cross Currency Swap Contracts [Member]</link:label>
    <link:label id="lab_amgn_CrossCurrencySwapContractsMember_documentation_en-US" xlink:label="lab_amgn_CrossCurrencySwapContractsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cross currency swap contracts.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CrossCurrencySwapContractsMember" xlink:href="amgn-20210930.xsd#amgn_CrossCurrencySwapContractsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_CrossCurrencySwapContractsMember" xlink:to="lab_amgn_CrossCurrencySwapContractsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_015beec8-8b01-472d-ac61-10b6fd6f7b95_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instruments and Hedging Activities Disclosure [Abstract]</link:label>
    <link:label id="lab_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_label_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instruments and Hedging Activities Disclosure [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:to="lab_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_52fe4a5c-358b-45f9-a573-bd0456679dbc_terseLabel_en-US" xlink:label="lab_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.70% notes due 2022 (2.70% 2022 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_label_en-US" xlink:label="lab_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Seven Zero Percent Notes Due Two Zero Two Two [Member]</link:label>
    <link:label id="lab_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_documentation_en-US" xlink:label="lab_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Seven Zero Percent Notes Due Two Zero Two Two [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember" xlink:href="amgn-20210930.xsd#amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember" xlink:to="lab_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_4471ae5b-102c-40c0-b1b5-eced5a28ba49_terseLabel_en-US" xlink:label="lab_us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Commitments and Contingencies Disclosure [Abstract]</link:label>
    <link:label id="lab_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_label_en-US" xlink:label="lab_us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Commitments and Contingencies Disclosure [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:to="lab_us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_A2.00SeniorNotesDue2026Member_a27db661-ef1a-4b2b-aba2-66a0bd6b915f_terseLabel_en-US" xlink:label="lab_amgn_A2.00SeniorNotesDue2026Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.00% Senior Notes Due 2026 [Member]</link:label>
    <link:label id="lab_amgn_A2.00SeniorNotesDue2026Member_label_en-US" xlink:label="lab_amgn_A2.00SeniorNotesDue2026Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.00% Senior Notes Due 2026 [Member]</link:label>
    <link:label id="lab_amgn_A2.00SeniorNotesDue2026Member_documentation_en-US" xlink:label="lab_amgn_A2.00SeniorNotesDue2026Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.00% Senior Notes Due 2026 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_A2.00SeniorNotesDue2026Member" xlink:href="amgn-20210930.xsd#amgn_A2.00SeniorNotesDue2026Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_A2.00SeniorNotesDue2026Member" xlink:to="lab_amgn_A2.00SeniorNotesDue2026Member" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityInteractiveDataCurrent_632f8445-7a15-4612-92b6-f8a5014b7ef9_terseLabel_en-US" xlink:label="lab_dei_EntityInteractiveDataCurrent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Interactive Data Current</link:label>
    <link:label id="lab_dei_EntityInteractiveDataCurrent_label_en-US" xlink:label="lab_dei_EntityInteractiveDataCurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Interactive Data Current</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInteractiveDataCurrent" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityInteractiveDataCurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityInteractiveDataCurrent" xlink:to="lab_dei_EntityInteractiveDataCurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NumberOfOperatingSegments_0a14e04c-4220-4957-ad6d-890013bc2fd6_terseLabel_en-US" xlink:label="lab_us-gaap_NumberOfOperatingSegments" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Number of operating segments</link:label>
    <link:label id="lab_us-gaap_NumberOfOperatingSegments_label_en-US" xlink:label="lab_us-gaap_NumberOfOperatingSegments" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Number of Operating Segments</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfOperatingSegments" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NumberOfOperatingSegments"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NumberOfOperatingSegments" xlink:to="lab_us-gaap_NumberOfOperatingSegments" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeFixedInterestRate_8894cbb3-0edb-42df-a97e-82afab868117_verboseLabel_en-US" xlink:label="lab_us-gaap_DerivativeFixedInterestRate" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest rates</link:label>
    <link:label id="lab_us-gaap_DerivativeFixedInterestRate_label_en-US" xlink:label="lab_us-gaap_DerivativeFixedInterestRate" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative, Fixed Interest Rate</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFixedInterestRate" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeFixedInterestRate"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeFixedInterestRate" xlink:to="lab_us-gaap_DerivativeFixedInterestRate" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EarningsPerShareBasic_e608a9cb-c5ba-4b8d-8ef1-952ca57dca89_verboseLabel_en-US" xlink:label="lab_us-gaap_EarningsPerShareBasic" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Basic (in usd per share)</link:label>
    <link:label id="lab_us-gaap_EarningsPerShareBasic_ed472645-f597-4607-9371-b4fd29762e93_terseLabel_en-US" xlink:label="lab_us-gaap_EarningsPerShareBasic" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Basic EPS (in usd per share)</link:label>
    <link:label id="lab_us-gaap_EarningsPerShareBasic_label_en-US" xlink:label="lab_us-gaap_EarningsPerShareBasic" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Earnings Per Share, Basic</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareBasic"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EarningsPerShareBasic" xlink:to="lab_us-gaap_EarningsPerShareBasic" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LossContingencyPendingClaimsNumber_95b36e80-aed9-452d-8e55-e5f0135d385d_terseLabel_en-US" xlink:label="lab_us-gaap_LossContingencyPendingClaimsNumber" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, Pending Claims, Number</link:label>
    <link:label id="lab_us-gaap_LossContingencyPendingClaimsNumber_label_en-US" xlink:label="lab_us-gaap_LossContingencyPendingClaimsNumber" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, Pending Claims, Number</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyPendingClaimsNumber" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyPendingClaimsNumber"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LossContingencyPendingClaimsNumber" xlink:to="lab_us-gaap_LossContingencyPendingClaimsNumber" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_18b8fb49-795c-4fe6-8443-e03f76b1c9fb_terseLabel_en-US" xlink:label="lab_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Indefinite-lived Intangible Assets, Major Class Name [Domain]</link:label>
    <link:label id="lab_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_label_en-US" xlink:label="lab_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Indefinite-lived Intangible Assets, Major Class Name [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:to="lab_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_RevenueFromContractWithCustomerTextBlock_1f0719c0-3e89-4414-895c-f01a74bff79c_terseLabel_en-US" xlink:label="lab_us-gaap_RevenueFromContractWithCustomerTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Revenues</link:label>
    <link:label id="lab_us-gaap_RevenueFromContractWithCustomerTextBlock_label_en-US" xlink:label="lab_us-gaap_RevenueFromContractWithCustomerTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Revenue from Contract with Customer [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerTextBlock" xlink:to="lab_us-gaap_RevenueFromContractWithCustomerTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_DocumentType_71031aa2-7798-4d6e-93d9-8fc8ad5fc0f5_terseLabel_en-US" xlink:label="lab_dei_DocumentType" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Type</link:label>
    <link:label id="lab_dei_DocumentType_label_en-US" xlink:label="lab_dei_DocumentType" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Type</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentType"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_DocumentType" xlink:to="lab_dei_DocumentType" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_TwoPointZeroPercent2032NotesMemberMember_6e2f33c1-efb7-4024-af13-cf8d5ecc2cae_terseLabel_en-US" xlink:label="lab_amgn_TwoPointZeroPercent2032NotesMemberMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.00% notes due 2032 (2.00% 2032 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointZeroPercent2032NotesMemberMember_label_en-US" xlink:label="lab_amgn_TwoPointZeroPercent2032NotesMemberMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two point zero percent 2032 Notes Member [Member]</link:label>
    <link:label id="lab_amgn_TwoPointZeroPercent2032NotesMemberMember_documentation_en-US" xlink:label="lab_amgn_TwoPointZeroPercent2032NotesMemberMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two point zero percent 2032 Notes Member</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointZeroPercent2032NotesMemberMember" xlink:href="amgn-20210930.xsd#amgn_TwoPointZeroPercent2032NotesMemberMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointZeroPercent2032NotesMemberMember" xlink:to="lab_amgn_TwoPointZeroPercent2032NotesMemberMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_RepathaevolocumabMember_80f38ac5-8163-425e-9b4b-dfc7a446bdf2_terseLabel_en-US" xlink:label="lab_amgn_RepathaevolocumabMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Repatha (evolocumab) [Member]</link:label>
    <link:label id="lab_amgn_RepathaevolocumabMember_label_en-US" xlink:label="lab_amgn_RepathaevolocumabMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Repatha (evolocumab) [Member]</link:label>
    <link:label id="lab_amgn_RepathaevolocumabMember_documentation_en-US" xlink:label="lab_amgn_RepathaevolocumabMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Repatha (evolocumab) [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_RepathaevolocumabMember" xlink:href="amgn-20210930.xsd#amgn_RepathaevolocumabMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_RepathaevolocumabMember" xlink:to="lab_amgn_RepathaevolocumabMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestExpenseDebt_309cab20-89f6-4e82-8ec2-adcf6d093bb7_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_InterestExpenseDebt" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest expense, net</link:label>
    <link:label id="lab_us-gaap_InterestExpenseDebt_label_en-US" xlink:label="lab_us-gaap_InterestExpenseDebt" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Expense, Debt</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebt" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestExpenseDebt"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestExpenseDebt" xlink:to="lab_us-gaap_InterestExpenseDebt" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DisaggregationOfRevenueTableTextBlock_44bf78bc-c72d-4e07-80a2-42d95ec67227_terseLabel_en-US" xlink:label="lab_us-gaap_DisaggregationOfRevenueTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Disaggregation of revenue by product and by geographic area</link:label>
    <link:label id="lab_us-gaap_DisaggregationOfRevenueTableTextBlock_label_en-US" xlink:label="lab_us-gaap_DisaggregationOfRevenueTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Disaggregation of Revenue [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DisaggregationOfRevenueTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DisaggregationOfRevenueTableTextBlock" xlink:to="lab_us-gaap_DisaggregationOfRevenueTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock_95f0328e-1b87-4bed-acf3-cf504b5ffd41_terseLabel_en-US" xlink:label="lab_amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of notional amounts and interest rates for cross-currency swaps</link:label>
    <link:label id="lab_amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock_label_en-US" xlink:label="lab_amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Notional Amounts and Interest Rates for Cross-Currency Swaps [Table Text Block]</link:label>
    <link:label id="lab_amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock_documentation_en-US" xlink:label="lab_amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Notional Amounts and Interest Rates for Cross-Currency Swaps</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock" xlink:href="amgn-20210930.xsd#amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock" xlink:to="lab_amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_TwoPointThreeZeroPercentNotesDue2031Member_7cd4e9ef-5d1b-4587-8f6c-aeeb1520c9b0_terseLabel_en-US" xlink:label="lab_amgn_TwoPointThreeZeroPercentNotesDue2031Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.30% notes due 2031 (2.30% 2031 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointThreeZeroPercentNotesDue2031Member_label_en-US" xlink:label="lab_amgn_TwoPointThreeZeroPercentNotesDue2031Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Three Zero Percent Notes Due 2031 [Member]</link:label>
    <link:label id="lab_amgn_TwoPointThreeZeroPercentNotesDue2031Member_documentation_en-US" xlink:label="lab_amgn_TwoPointThreeZeroPercentNotesDue2031Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Three Zero Percent Notes Due 2031</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointThreeZeroPercentNotesDue2031Member" xlink:href="amgn-20210930.xsd#amgn_TwoPointThreeZeroPercentNotesDue2031Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointThreeZeroPercentNotesDue2031Member" xlink:to="lab_amgn_TwoPointThreeZeroPercentNotesDue2031Member" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityCurrentReportingStatus_3d46afd7-6bc7-461e-a84f-205b5691974f_terseLabel_en-US" xlink:label="lab_dei_EntityCurrentReportingStatus" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Current Reporting Status</link:label>
    <link:label id="lab_dei_EntityCurrentReportingStatus_label_en-US" xlink:label="lab_dei_EntityCurrentReportingStatus" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Current Reporting Status</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCurrentReportingStatus" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCurrentReportingStatus"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityCurrentReportingStatus" xlink:to="lab_dei_EntityCurrentReportingStatus" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_b26a201d-35db-44d3-b121-6a1921223ac5_terseLabel_en-US" xlink:label="lab_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cumulative effect of changes in accounting principles, net of tax</link:label>
    <link:label id="lab_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_label_en-US" xlink:label="lab_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cumulative Effect, Period of Adoption, Adjustment [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember" xlink:to="lab_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherNoncashIncomeExpense_77fae1b9-2dc3-4958-9a73-0bacd9445387_negatedLabel_en-US" xlink:label="lab_us-gaap_OtherNoncashIncomeExpense" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other items, net</link:label>
    <link:label id="lab_us-gaap_OtherNoncashIncomeExpense_label_en-US" xlink:label="lab_us-gaap_OtherNoncashIncomeExpense" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Noncash Income (Expense)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoncashIncomeExpense" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherNoncashIncomeExpense"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherNoncashIncomeExpense" xlink:to="lab_us-gaap_OtherNoncashIncomeExpense" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeFairValueOfDerivativeAsset_8b00a474-ebba-4e70-97b0-b3220677a8ef_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeFairValueOfDerivativeAsset" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total derivative assets, fair value</link:label>
    <link:label id="lab_us-gaap_DerivativeFairValueOfDerivativeAsset_label_en-US" xlink:label="lab_us-gaap_DerivativeFairValueOfDerivativeAsset" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Asset, Fair Value, Gross Asset</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeAsset" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeAsset"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeFairValueOfDerivativeAsset" xlink:to="lab_us-gaap_DerivativeFairValueOfDerivativeAsset" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LossContingencyNumberOfPlaintiffs_ecf39e90-c0e7-441c-ab27-c6f601b0f27c_terseLabel_en-US" xlink:label="lab_us-gaap_LossContingencyNumberOfPlaintiffs" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Number of plaintiffs</link:label>
    <link:label id="lab_us-gaap_LossContingencyNumberOfPlaintiffs_label_en-US" xlink:label="lab_us-gaap_LossContingencyNumberOfPlaintiffs" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, Number of Plaintiffs</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNumberOfPlaintiffs" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyNumberOfPlaintiffs"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LossContingencyNumberOfPlaintiffs" xlink:to="lab_us-gaap_LossContingencyNumberOfPlaintiffs" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_LossContingencyPatentsExpiredNumber_385978f8-2edb-485f-a3bd-1b1d11f85ead_terseLabel_en-US" xlink:label="lab_amgn_LossContingencyPatentsExpiredNumber" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Number of asserted patents expired</link:label>
    <link:label id="lab_amgn_LossContingencyPatentsExpiredNumber_label_en-US" xlink:label="lab_amgn_LossContingencyPatentsExpiredNumber" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, Patents Expired, Number</link:label>
    <link:label id="lab_amgn_LossContingencyPatentsExpiredNumber_documentation_en-US" xlink:label="lab_amgn_LossContingencyPatentsExpiredNumber" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, Patents Expired, Number</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LossContingencyPatentsExpiredNumber" xlink:href="amgn-20210930.xsd#amgn_LossContingencyPatentsExpiredNumber"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_LossContingencyPatentsExpiredNumber" xlink:to="lab_amgn_LossContingencyPatentsExpiredNumber" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtInstrumentCarryingAmount_b98f34ad-7b56-4595-bb5a-e755b8464187_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentCarryingAmount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term debt, gross</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentCarryingAmount_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentCarryingAmount" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term Debt, Gross</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount" xlink:to="lab_us-gaap_DebtInstrumentCarryingAmount" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_GoodwillRollForward_acf80332-cc96-4107-b507-fce586957f21_terseLabel_en-US" xlink:label="lab_us-gaap_GoodwillRollForward" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Goodwill [Roll Forward]</link:label>
    <link:label id="lab_us-gaap_GoodwillRollForward_label_en-US" xlink:label="lab_us-gaap_GoodwillRollForward" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Goodwill [Roll Forward]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillRollForward" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GoodwillRollForward"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_GoodwillRollForward" xlink:to="lab_us-gaap_GoodwillRollForward" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_StockRepurchaseProgramTableTextBlock_7f659582-ae12-4fa7-8793-88d2b15f5fe9_terseLabel_en-US" xlink:label="lab_amgn_StockRepurchaseProgramTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Summary of activity under our stock repurchase program</link:label>
    <link:label id="lab_amgn_StockRepurchaseProgramTableTextBlock_label_en-US" xlink:label="lab_amgn_StockRepurchaseProgramTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock Repurchase Program [Table Text Block]</link:label>
    <link:label id="lab_amgn_StockRepurchaseProgramTableTextBlock_documentation_en-US" xlink:label="lab_amgn_StockRepurchaseProgramTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock Repurchase Program [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_StockRepurchaseProgramTableTextBlock" xlink:href="amgn-20210930.xsd#amgn_StockRepurchaseProgramTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_StockRepurchaseProgramTableTextBlock" xlink:to="lab_amgn_StockRepurchaseProgramTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AssetsFairValueDisclosureAbstract_db87c32c-1f3d-40c9-93d1-ea83979b3550_verboseLabel_en-US" xlink:label="lab_us-gaap_AssetsFairValueDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets:</link:label>
    <link:label id="lab_us-gaap_AssetsFairValueDisclosureAbstract_label_en-US" xlink:label="lab_us-gaap_AssetsFairValueDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets, Fair Value Disclosure [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosureAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsFairValueDisclosureAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract" xlink:to="lab_us-gaap_AssetsFairValueDisclosureAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_CorporateDebtSecuritiesIndustrialMember_1aa21b65-b1dc-4c36-a5ea-151785fe2ab2_terseLabel_en-US" xlink:label="lab_amgn_CorporateDebtSecuritiesIndustrialMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Corporate debt securities - Industrial [Member]</link:label>
    <link:label id="lab_amgn_CorporateDebtSecuritiesIndustrialMember_label_en-US" xlink:label="lab_amgn_CorporateDebtSecuritiesIndustrialMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Corporate Debt Securities Industrial [Member]</link:label>
    <link:label id="lab_amgn_CorporateDebtSecuritiesIndustrialMember_documentation_en-US" xlink:label="lab_amgn_CorporateDebtSecuritiesIndustrialMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Corporate debt securities industrial Member.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesIndustrialMember" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesIndustrialMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_CorporateDebtSecuritiesIndustrialMember" xlink:to="lab_amgn_CorporateDebtSecuritiesIndustrialMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LongTermDebt_4b080a1b-02c1-44e9-9406-b5333d9a4deb_totalLabel_en-US" xlink:label="lab_us-gaap_LongTermDebt" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total carrying value of debt</link:label>
    <link:label id="lab_us-gaap_LongTermDebt_7a7f9055-d1ee-45f3-b377-17441ad4bfc1_terseLabel_en-US" xlink:label="lab_us-gaap_LongTermDebt" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Carrying value of debt</link:label>
    <link:label id="lab_us-gaap_LongTermDebt_label_en-US" xlink:label="lab_us-gaap_LongTermDebt" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term Debt</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebt"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LongTermDebt" xlink:to="lab_us-gaap_LongTermDebt" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AssetsFairValueDisclosure_60752210-9ae4-48ac-be47-ce7ce6af3fdf_totalLabel_en-US" xlink:label="lab_us-gaap_AssetsFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total assets</link:label>
    <link:label id="lab_us-gaap_AssetsFairValueDisclosure_label_en-US" xlink:label="lab_us-gaap_AssetsFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets, Fair Value Disclosure</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AssetsFairValueDisclosure" xlink:to="lab_us-gaap_AssetsFairValueDisclosure" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueInputsLevel1Member_a7c88c96-3463-4c17-8498-148fe475bfac_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel1Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, Inputs, Level 1 [Member]</link:label>
    <link:label id="lab_us-gaap_FairValueInputsLevel1Member_72a202ef-b4fa-4103-8b7d-2790919ab4d8_verboseLabel_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel1Member" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Quoted prices in active markets for identical assets (Level 1) [Member]</link:label>
    <link:label id="lab_us-gaap_FairValueInputsLevel1Member_label_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel1Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, Inputs, Level 1 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueInputsLevel1Member" xlink:to="lab_us-gaap_FairValueInputsLevel1Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_92dabe68-df65-43a7-bfa3-2a0f5ea19bde_verboseLabel_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash flows from investing activities:</link:label>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_label_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Cash Provided by (Used in) Investing Activities [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:to="lab_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_754e6b32-33ab-40d3-898c-e310d9053257_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value by Liability Class [Domain]</link:label>
    <link:label id="lab_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_label_en-US" xlink:label="lab_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value by Liability Class [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:to="lab_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_DocumentTransitionReport_9ce690c4-fa53-4589-aaa3-bd5ca23d811a_terseLabel_en-US" xlink:label="lab_dei_DocumentTransitionReport" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Transition Report</link:label>
    <link:label id="lab_dei_DocumentTransitionReport_label_en-US" xlink:label="lab_dei_DocumentTransitionReport" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Transition Report</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentTransitionReport" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentTransitionReport"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_DocumentTransitionReport" xlink:to="lab_dei_DocumentTransitionReport" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncomeTaxDisclosureAbstract_82d3c8e7-9154-41fc-ab55-6df1ce742500_terseLabel_en-US" xlink:label="lab_us-gaap_IncomeTaxDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income Tax Disclosure [Abstract]</link:label>
    <link:label id="lab_us-gaap_IncomeTaxDisclosureAbstract_label_en-US" xlink:label="lab_us-gaap_IncomeTaxDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income Tax Disclosure [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract" xlink:to="lab_us-gaap_IncomeTaxDisclosureAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_AvailableForSalesInvestmentsMember_0e2be38c-abed-4a6b-bbf4-7d79fba7c8bb_verboseLabel_en-US" xlink:label="lab_amgn_AvailableForSalesInvestmentsMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Available-for-sale investments [Member]</link:label>
    <link:label id="lab_amgn_AvailableForSalesInvestmentsMember_label_en-US" xlink:label="lab_amgn_AvailableForSalesInvestmentsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Available For Sales Investments [Member]</link:label>
    <link:label id="lab_amgn_AvailableForSalesInvestmentsMember_documentation_en-US" xlink:label="lab_amgn_AvailableForSalesInvestmentsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Available for sales investments.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AvailableForSalesInvestmentsMember" xlink:href="amgn-20210930.xsd#amgn_AvailableForSalesInvestmentsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_AvailableForSalesInvestmentsMember" xlink:to="lab_amgn_AvailableForSalesInvestmentsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_IncreaseDecreaseInNoncurrentTaxLiability_cba00a43-b5d1-4bc2-a766-e6146fa71a22_terseLabel_en-US" xlink:label="lab_amgn_IncreaseDecreaseInNoncurrentTaxLiability" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term tax liabilities</link:label>
    <link:label id="lab_amgn_IncreaseDecreaseInNoncurrentTaxLiability_label_en-US" xlink:label="lab_amgn_IncreaseDecreaseInNoncurrentTaxLiability" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) In Noncurrent Tax Liability</link:label>
    <link:label id="lab_amgn_IncreaseDecreaseInNoncurrentTaxLiability_documentation_en-US" xlink:label="lab_amgn_IncreaseDecreaseInNoncurrentTaxLiability" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) In Noncurrent Tax Liability</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_IncreaseDecreaseInNoncurrentTaxLiability" xlink:href="amgn-20210930.xsd#amgn_IncreaseDecreaseInNoncurrentTaxLiability"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_IncreaseDecreaseInNoncurrentTaxLiability" xlink:to="lab_amgn_IncreaseDecreaseInNoncurrentTaxLiability" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions_035d7dc0-0fbe-4afe-b35f-cc92fc476119_terseLabel_en-US" xlink:label="lab_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase in unrecognized tax benefits resulting from tax positions taken during the current period</link:label>
    <link:label id="lab_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions_label_en-US" xlink:label="lab_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions" xlink:to="lab_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsLineItems_d5c84e65-bf7d-4d1f-b6f2-df6d9708d9d7_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Assets [Line Items]</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsLineItems_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Assets [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LiabilitiesAndStockholdersEquity_ba5f7d4d-e052-4219-8892-95b7157a79f7_totalLabel_en-US" xlink:label="lab_us-gaap_LiabilitiesAndStockholdersEquity" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total liabilities and stockholders&#8217; equity</link:label>
    <link:label id="lab_us-gaap_LiabilitiesAndStockholdersEquity_label_en-US" xlink:label="lab_us-gaap_LiabilitiesAndStockholdersEquity" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liabilities and Equity</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity" xlink:to="lab_us-gaap_LiabilitiesAndStockholdersEquity" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_472af5dc-c29b-4462-89ff-5a31d7032002_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments, Debt and Equity Securities [Abstract]</link:label>
    <link:label id="lab_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_label_en-US" xlink:label="lab_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments, Debt and Equity Securities [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract" xlink:to="lab_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_NatureOfOperationsPolicyTextBlock_cc7517c2-0465-4e00-9cda-02b2f7a50efd_verboseLabel_en-US" xlink:label="lab_amgn_NatureOfOperationsPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business</link:label>
    <link:label id="lab_amgn_NatureOfOperationsPolicyTextBlock_label_en-US" xlink:label="lab_amgn_NatureOfOperationsPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Nature Of Operations [Policy Text Block]</link:label>
    <link:label id="lab_amgn_NatureOfOperationsPolicyTextBlock_documentation_en-US" xlink:label="lab_amgn_NatureOfOperationsPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Describes the nature of an entity's business, the major products or services it sells or provides and its principal markets, including the locations of those markets. If the entity operates in more than one business, the disclosure also indicates the relative importance of its operations in each business and the basis for the determination (for example, assets, revenues, or earnings). Disclosures about the nature of operations need not be quantified; relative importance could be conveyed by use of terms such as "predominately", "about equally", or "major and other". This element is also referred to as "Business Description".</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_NatureOfOperationsPolicyTextBlock" xlink:href="amgn-20210930.xsd#amgn_NatureOfOperationsPolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_NatureOfOperationsPolicyTextBlock" xlink:to="lab_amgn_NatureOfOperationsPolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments_27f0fdd2-31b8-4dd6-86b4-a8ba42446967_terseLabel_en-US" xlink:label="lab_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Revenue Recognition, Milestone Method, Potential Future Milestone payments</link:label>
    <link:label id="lab_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments_label_en-US" xlink:label="lab_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Revenue Recognition, Milestone Method, Potential Future Milestone payments</link:label>
    <link:label id="lab_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments_documentation_en-US" xlink:label="lab_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Revenue Recognition, Milestone Method, Potential Future Milestone Payments</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments" xlink:href="amgn-20210930.xsd#amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments" xlink:to="lab_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_DebtExchangeAdditionalCashConsideration_b7ad5bcf-008f-4edc-8bd7-695d9ebb1bb6_terseLabel_en-US" xlink:label="lab_amgn_DebtExchangeAdditionalCashConsideration" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">debt exchange additional cash consideration</link:label>
    <link:label id="lab_amgn_DebtExchangeAdditionalCashConsideration_label_en-US" xlink:label="lab_amgn_DebtExchangeAdditionalCashConsideration" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt exchange additional cash consideration</link:label>
    <link:label id="lab_amgn_DebtExchangeAdditionalCashConsideration_documentation_en-US" xlink:label="lab_amgn_DebtExchangeAdditionalCashConsideration" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt exchange additional cash consideration paid</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DebtExchangeAdditionalCashConsideration" xlink:href="amgn-20210930.xsd#amgn_DebtExchangeAdditionalCashConsideration"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_DebtExchangeAdditionalCashConsideration" xlink:to="lab_amgn_DebtExchangeAdditionalCashConsideration" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_StatementScenarioAxis_3c80810b-9fed-4602-80d8-ac2f11ec6e3a_terseLabel_en-US" xlink:label="lab_srt_StatementScenarioAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Scenario [Axis]</link:label>
    <link:label id="lab_srt_StatementScenarioAxis_label_en-US" xlink:label="lab_srt_StatementScenarioAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Scenario [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementScenarioAxis" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_StatementScenarioAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_StatementScenarioAxis" xlink:to="lab_srt_StatementScenarioAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_93612358-c2f5-4643-825b-d777bc69ee86_terseLabel_en-US" xlink:label="lab_amgn_ThreePointEightSevenFivePercentNotesDue2021Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">3.875% notes due 2021 (3.875% 2021 Notes) [Member]</link:label>
    <link:label id="lab_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_label_en-US" xlink:label="lab_amgn_ThreePointEightSevenFivePercentNotesDue2021Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point Eight Seven Five Percent Notes Due 2021 [Member]</link:label>
    <link:label id="lab_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_documentation_en-US" xlink:label="lab_amgn_ThreePointEightSevenFivePercentNotesDue2021Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point Eight Seven Five Percent Notes Due 2021 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointEightSevenFivePercentNotesDue2021Member" xlink:href="amgn-20210930.xsd#amgn_ThreePointEightSevenFivePercentNotesDue2021Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ThreePointEightSevenFivePercentNotesDue2021Member" xlink:to="lab_amgn_ThreePointEightSevenFivePercentNotesDue2021Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_2b5a1752-5276-408a-b7aa-5669bed38701_terseLabel_en-US" xlink:label="lab_us-gaap_USGovernmentAgenciesDebtSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other government-related debt securities - U.S. [Member]</link:label>
    <link:label id="lab_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_label_en-US" xlink:label="lab_us-gaap_USGovernmentAgenciesDebtSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">US Government Agencies Debt Securities [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USGovernmentAgenciesDebtSecuritiesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember" xlink:to="lab_us-gaap_USGovernmentAgenciesDebtSecuritiesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LiabilitiesAndStockholdersEquityAbstract_d7d6b8bc-615e-4046-80ee-6eabd3df4db2_verboseLabel_en-US" xlink:label="lab_us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">LIABILITIES AND STOCKHOLDERS&#8217; EQUITY</link:label>
    <link:label id="lab_us-gaap_LiabilitiesAndStockholdersEquityAbstract_label_en-US" xlink:label="lab_us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liabilities and Equity [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:to="lab_us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_815d248f-8a72-4d5a-a532-e78ef760a11e_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investment Income [Table]</link:label>
    <link:label id="lab_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_label_en-US" xlink:label="lab_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investment Income [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable" xlink:to="lab_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncreaseDecreaseInAccountsPayable_df3b4637-4fc4-41b0-97af-8a5e165faf8a_verboseLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInAccountsPayable" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accounts payable</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInAccountsPayable_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInAccountsPayable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) in Accounts Payable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncreaseDecreaseInAccountsPayable" xlink:to="lab_us-gaap_IncreaseDecreaseInAccountsPayable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeLineItems_ee525c0a-fd18-4e10-9474-590cec6a260b_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative [Line Items]</link:label>
    <link:label id="lab_us-gaap_DerivativeLineItems_label_en-US" xlink:label="lab_us-gaap_DerivativeLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeLineItems" xlink:to="lab_us-gaap_DerivativeLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestRateSwapMember_44e2e751-9b77-4f0f-9153-ae1db5d839aa_verboseLabel_en-US" xlink:label="lab_us-gaap_InterestRateSwapMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest rate swap contracts [Member]</link:label>
    <link:label id="lab_us-gaap_InterestRateSwapMember_9bd833c3-0bec-417a-aa5e-c64a94681057_terseLabel_en-US" xlink:label="lab_us-gaap_InterestRateSwapMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Rate Swap [Member]</link:label>
    <link:label id="lab_us-gaap_InterestRateSwapMember_f8b09f3c-3ac8-4ae4-b58b-c35515abdc7a_netLabel_en-US" xlink:label="lab_us-gaap_InterestRateSwapMember" xlink:role="http://www.xbrl.org/2009/role/netLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest rate swap agreements [Member]</link:label>
    <link:label id="lab_us-gaap_InterestRateSwapMember_label_en-US" xlink:label="lab_us-gaap_InterestRateSwapMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Rate Swap [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateSwapMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestRateSwapMember" xlink:to="lab_us-gaap_InterestRateSwapMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_HedgingRelationshipDomain_3aab0aef-dc93-4040-800e-af2aa8506abd_terseLabel_en-US" xlink:label="lab_us-gaap_HedgingRelationshipDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedging Relationship [Domain]</link:label>
    <link:label id="lab_us-gaap_HedgingRelationshipDomain_label_en-US" xlink:label="lab_us-gaap_HedgingRelationshipDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedging Relationship [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_HedgingRelationshipDomain" xlink:to="lab_us-gaap_HedgingRelationshipDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure_4a1e26c0-cc33-4b83-b353-2aa2fb16fba0_verboseLabel_en-US" xlink:label="lab_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Foreign currency and cross-currency swap contracts</link:label>
    <link:label id="lab_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure_label_en-US" xlink:label="lab_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Foreign Currency Contract, Asset, Fair Value Disclosure</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignCurrencyContractAssetFairValueDisclosure"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure" xlink:to="lab_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EarningsPerShareTextBlock_4f5cd7da-cff7-4037-ab44-ae7b9ff3176f_verboseLabel_en-US" xlink:label="lab_us-gaap_EarningsPerShareTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Earnings per share</link:label>
    <link:label id="lab_us-gaap_EarningsPerShareTextBlock_label_en-US" xlink:label="lab_us-gaap_EarningsPerShareTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Earnings Per Share [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EarningsPerShareTextBlock" xlink:to="lab_us-gaap_EarningsPerShareTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock_6b6695ec-a993-42ba-b352-ab4b508c43d0_verboseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Unrealized gain (loss) recognized in Other Comprehensive Income for our derivative instruments designated as cash flow hedges</link:label>
    <link:label id="lab_us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Cash Flow Hedges Included in Accumulated Other Comprehensive Income (Loss) [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:to="lab_us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EquityMethodInvestmentOwnershipPercentage_aa04d284-9ec3-4d0c-b6a3-e2f23a2ee94d_terseLabel_en-US" xlink:label="lab_us-gaap_EquityMethodInvestmentOwnershipPercentage" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Ownership percentage</link:label>
    <link:label id="lab_us-gaap_EquityMethodInvestmentOwnershipPercentage_label_en-US" xlink:label="lab_us-gaap_EquityMethodInvestmentOwnershipPercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investment, Ownership Percentage</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentOwnershipPercentage"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage" xlink:to="lab_us-gaap_EquityMethodInvestmentOwnershipPercentage" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_CorporateDebtSecuritiesOtherMember_2bbfa089-16f1-414f-99c3-8f448a0f7074_terseLabel_en-US" xlink:label="lab_amgn_CorporateDebtSecuritiesOtherMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Corporate debt securities - Other [Member]</link:label>
    <link:label id="lab_amgn_CorporateDebtSecuritiesOtherMember_label_en-US" xlink:label="lab_amgn_CorporateDebtSecuritiesOtherMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Corporate Debt Securities Other [Member]</link:label>
    <link:label id="lab_amgn_CorporateDebtSecuritiesOtherMember_documentation_en-US" xlink:label="lab_amgn_CorporateDebtSecuritiesOtherMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Corporate debt securities other.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesOtherMember" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesOtherMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_CorporateDebtSecuritiesOtherMember" xlink:to="lab_amgn_CorporateDebtSecuritiesOtherMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_633ce2b4-a954-4166-8673-f913cdc15ae2_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total estimated amortization of finite-lived intangible assets for 2025</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Year Four</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_HumiraBiosimilarAntitrustClassActionsMember_382c733d-ae95-4416-b554-375e4f4f7921_terseLabel_en-US" xlink:label="lab_amgn_HumiraBiosimilarAntitrustClassActionsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Humira Biosimilar Antitrust Class Actions [Member]</link:label>
    <link:label id="lab_amgn_HumiraBiosimilarAntitrustClassActionsMember_label_en-US" xlink:label="lab_amgn_HumiraBiosimilarAntitrustClassActionsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Humira Biosimilar Antitrust Class Actions [Member]</link:label>
    <link:label id="lab_amgn_HumiraBiosimilarAntitrustClassActionsMember_documentation_en-US" xlink:label="lab_amgn_HumiraBiosimilarAntitrustClassActionsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Humira Biosimilar Antitrust Class Actions [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_HumiraBiosimilarAntitrustClassActionsMember" xlink:href="amgn-20210930.xsd#amgn_HumiraBiosimilarAntitrustClassActionsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_HumiraBiosimilarAntitrustClassActionsMember" xlink:to="lab_amgn_HumiraBiosimilarAntitrustClassActionsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_MinimumMember_42b35be8-9424-4258-8892-62120f113bbe_terseLabel_en-US" xlink:label="lab_srt_MinimumMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Minimum [Member]</link:label>
    <link:label id="lab_srt_MinimumMember_label_en-US" xlink:label="lab_srt_MinimumMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Minimum [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MinimumMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_MinimumMember" xlink:to="lab_srt_MinimumMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_KyowaKirinCoLtdMember_bdd91f4c-7e52-468d-b595-4bc7d3c3028b_terseLabel_en-US" xlink:label="lab_amgn_KyowaKirinCoLtdMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Kyowa Kirin Co. Ltd.</link:label>
    <link:label id="lab_amgn_KyowaKirinCoLtdMember_label_en-US" xlink:label="lab_amgn_KyowaKirinCoLtdMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Kyowa Kirin Co. Ltd. [Member]</link:label>
    <link:label id="lab_amgn_KyowaKirinCoLtdMember_documentation_en-US" xlink:label="lab_amgn_KyowaKirinCoLtdMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Kyowa Kirin Co. Ltd.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_KyowaKirinCoLtdMember" xlink:href="amgn-20210930.xsd#amgn_KyowaKirinCoLtdMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_KyowaKirinCoLtdMember" xlink:to="lab_amgn_KyowaKirinCoLtdMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleRealizedGain_5fe952c1-7804-4743-84dc-7e21008fa9de_verboseLabel_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleRealizedGain" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total realized gains</link:label>
    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleRealizedGain_label_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleRealizedGain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale, Realized Gain</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleRealizedGain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGain" xlink:to="lab_us-gaap_DebtSecuritiesAvailableForSaleRealizedGain" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_d09c015d-fddf-487c-b6ec-89518aae6145_terseLabel_en-US" xlink:label="lab_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">4.40% notes due 2045 (4.40% 2045 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_label_en-US" xlink:label="lab_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Four Point Four Zero Percent Notes Due Two Zero Four Five [Member]</link:label>
    <link:label id="lab_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_documentation_en-US" xlink:label="lab_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Four Point Four Zero Percent Notes Due Two Zero Four Five [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember" xlink:href="amgn-20210930.xsd#amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember" xlink:to="lab_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent_83ec1ebd-755f-410d-b196-db839b2b9743_terseLabel_en-US" xlink:label="lab_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term tax liabilities</link:label>
    <link:label id="lab_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent_label_en-US" xlink:label="lab_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liability for Uncertainty in Income Taxes, Noncurrent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilityForUncertainTaxPositionsNoncurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent" xlink:to="lab_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_BalanceSheetLocationDomain_b3246fb4-a06b-4c24-98fd-7180e0b68a07_terseLabel_en-US" xlink:label="lab_us-gaap_BalanceSheetLocationDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Balance Sheet Location [Domain]</link:label>
    <link:label id="lab_us-gaap_BalanceSheetLocationDomain_label_en-US" xlink:label="lab_us-gaap_BalanceSheetLocationDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Balance Sheet Location [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BalanceSheetLocationDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BalanceSheetLocationDomain" xlink:to="lab_us-gaap_BalanceSheetLocationDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LiabilitiesFairValueDisclosure_bc727a76-4e62-40e1-8be4-1a85cffc3e21_totalLabel_en-US" xlink:label="lab_us-gaap_LiabilitiesFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total liabilities</link:label>
    <link:label id="lab_us-gaap_LiabilitiesFairValueDisclosure_label_en-US" xlink:label="lab_us-gaap_LiabilitiesFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial and Nonfinancial Liabilities, Fair Value Disclosure</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure" xlink:to="lab_us-gaap_LiabilitiesFairValueDisclosure" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_e9917bc1-9ef8-451f-a537-06ed6874191e_totalLabel_en-US" xlink:label="lab_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income before income taxes</link:label>
    <link:label id="lab_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_3a8a140e-b00a-4fa2-bbad-cb5c840996cb_terseLabel_en-US" xlink:label="lab_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income before income taxes</link:label>
    <link:label id="lab_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_label_en-US" xlink:label="lab_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Noncontrolling Interest</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:to="lab_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SellingGeneralAndAdministrativeExpense_33ea6c64-0f3d-40bd-9cc5-b9e8986bba33_verboseLabel_en-US" xlink:label="lab_us-gaap_SellingGeneralAndAdministrativeExpense" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Selling, general and administrative</link:label>
    <link:label id="lab_us-gaap_SellingGeneralAndAdministrativeExpense_label_en-US" xlink:label="lab_us-gaap_SellingGeneralAndAdministrativeExpense" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Selling, General and Administrative Expense</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SellingGeneralAndAdministrativeExpense" xlink:to="lab_us-gaap_SellingGeneralAndAdministrativeExpense" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_3a2826db-c73e-4240-928b-d191110a44aa_terseLabel_en-US" xlink:label="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Indefinite-lived Intangible Assets [Axis]</link:label>
    <link:label id="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_label_en-US" xlink:label="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Indefinite-lived Intangible Assets [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:to="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract_f84e203d-65c1-4ecd-887b-56fba0a00ac4_terseLabel_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other comprehensive income (loss), net of reclassification adjustments and taxes:</link:label>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract_label_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract" xlink:to="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_ca9ef7c5-c696-44ac-8a4b-fc14fb7ef21f_terseLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Gross unrealized gains</link:label>
    <link:label id="lab_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_label_en-US" xlink:label="lab_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale, Accumulated Gross Unrealized Gain, before Tax</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" xlink:to="lab_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months_acba08ad-fd47-44ea-98db-0c635d519276_terseLabel_en-US" xlink:label="lab_us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amounts expected to be reclassified from AOCI into earnings over the next 12 months, foreign currency and cross-currency swaps</link:label>
    <link:label id="lab_us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months_label_en-US" xlink:label="lab_us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Foreign Currency Cash Flow Hedge Gain (Loss) to be Reclassified During Next 12 Months</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months" xlink:to="lab_us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_CumulativeEffectPeriodOfAdoptionAxis_869243f8-2838-4ee1-8035-0352972da5e7_terseLabel_en-US" xlink:label="lab_srt_CumulativeEffectPeriodOfAdoptionAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cumulative Effect, Period of Adoption [Axis]</link:label>
    <link:label id="lab_srt_CumulativeEffectPeriodOfAdoptionAxis_label_en-US" xlink:label="lab_srt_CumulativeEffectPeriodOfAdoptionAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cumulative Effect, Period of Adoption [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAxis" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionAxis" xlink:to="lab_srt_CumulativeEffectPeriodOfAdoptionAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember_dcd49a5e-900e-4c1f-bcee-884fd10cc064_terseLabel_en-US" xlink:label="lab_amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">1.90% notes due 2025 (1.90% 2025 Notes) [Member]</link:label>
    <link:label id="lab_amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember_label_en-US" xlink:label="lab_amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">One Point Nine Zero Percent Notes Due Two Zero Two Five [Member]</link:label>
    <link:label id="lab_amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember_documentation_en-US" xlink:label="lab_amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">One Point Nine Zero Percent Notes Due Two Zero Two Five [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember" xlink:href="amgn-20210930.xsd#amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember" xlink:to="lab_amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_TradingSymbol_76e237c9-bafb-4d05-9ffc-9f12455352bf_terseLabel_en-US" xlink:label="lab_dei_TradingSymbol" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Trading Symbol</link:label>
    <link:label id="lab_dei_TradingSymbol_label_en-US" xlink:label="lab_dei_TradingSymbol" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Trading Symbol</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_TradingSymbol"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_TradingSymbol" xlink:to="lab_dei_TradingSymbol" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount_8612fc89-b7e8-4d1b-a68f-02da334703a9_terseLabel_en-US" xlink:label="lab_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument, Redemption Period without Payment of Make Whole Amount</link:label>
    <link:label id="lab_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount_label_en-US" xlink:label="lab_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument, Redemption Period without Payment of Make Whole Amount</link:label>
    <link:label id="lab_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount_documentation_en-US" xlink:label="lab_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument, Redemption Period without Payment of Make Whole Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount" xlink:href="amgn-20210930.xsd#amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount" xlink:to="lab_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LiabilitiesCurrentAbstract_4b70c7a9-f17c-44e8-85a1-c5bf90991ebc_verboseLabel_en-US" xlink:label="lab_us-gaap_LiabilitiesCurrentAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current liabilities:</link:label>
    <link:label id="lab_us-gaap_LiabilitiesCurrentAbstract_label_en-US" xlink:label="lab_us-gaap_LiabilitiesCurrentAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liabilities, Current [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract" xlink:to="lab_us-gaap_LiabilitiesCurrentAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_1b7f087a-2fe4-430f-a230-0797de871b7d_negatedLabel_en-US" xlink:label="lab_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Payments to Acquire Businesses, Net of Cash Acquired</link:label>
    <link:label id="lab_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_2f37be91-5fa7-43a7-a3d5-b071cd131bcd_verboseLabel_en-US" xlink:label="lab_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Payments to Acquire Businesses, Net of Cash Acquired</link:label>
    <link:label id="lab_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_label_en-US" xlink:label="lab_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Payments to Acquire Businesses, Net of Cash Acquired</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired" xlink:to="lab_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccumulatedTranslationAdjustmentMember_1de741f3-c0e6-4f5f-9260-02a5e8618c03_terseLabel_en-US" xlink:label="lab_us-gaap_AccumulatedTranslationAdjustmentMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Foreign currency translation [Member]</link:label>
    <link:label id="lab_us-gaap_AccumulatedTranslationAdjustmentMember_label_en-US" xlink:label="lab_us-gaap_AccumulatedTranslationAdjustmentMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated Foreign Currency Adjustment Attributable to Parent [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedTranslationAdjustmentMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedTranslationAdjustmentMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccumulatedTranslationAdjustmentMember" xlink:to="lab_us-gaap_AccumulatedTranslationAdjustmentMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtDisclosureTextBlock_2cb1c4ff-6bb3-4b33-b23b-d135679995f6_verboseLabel_en-US" xlink:label="lab_us-gaap_DebtDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financing arrangements</link:label>
    <link:label id="lab_us-gaap_DebtDisclosureTextBlock_label_en-US" xlink:label="lab_us-gaap_DebtDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Disclosure [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtDisclosureTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtDisclosureTextBlock" xlink:to="lab_us-gaap_DebtDisclosureTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_EquityMethodInvestmentChangeInCarryingValue_bebe6b47-222e-4780-a0c3-cf6831dc9c2b_terseLabel_en-US" xlink:label="lab_amgn_EquityMethodInvestmentChangeInCarryingValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity method investment, change in carrying value</link:label>
    <link:label id="lab_amgn_EquityMethodInvestmentChangeInCarryingValue_label_en-US" xlink:label="lab_amgn_EquityMethodInvestmentChangeInCarryingValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity method investment, change in carrying value</link:label>
    <link:label id="lab_amgn_EquityMethodInvestmentChangeInCarryingValue_documentation_en-US" xlink:label="lab_amgn_EquityMethodInvestmentChangeInCarryingValue" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity method investment, change in carrying value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_EquityMethodInvestmentChangeInCarryingValue" xlink:href="amgn-20210930.xsd#amgn_EquityMethodInvestmentChangeInCarryingValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_EquityMethodInvestmentChangeInCarryingValue" xlink:to="lab_amgn_EquityMethodInvestmentChangeInCarryingValue" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FourPointOneZeroPercentNotesDue2021Member_5082a39e-05f6-4639-9e8d-0ae544b9335b_terseLabel_en-US" xlink:label="lab_amgn_FourPointOneZeroPercentNotesDue2021Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">4.10% notes due 2021 (4.10% 2021 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPointOneZeroPercentNotesDue2021Member_label_en-US" xlink:label="lab_amgn_FourPointOneZeroPercentNotesDue2021Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Four Point One Zero Percent Notes Due 2021 [Member]</link:label>
    <link:label id="lab_amgn_FourPointOneZeroPercentNotesDue2021Member_documentation_en-US" xlink:label="lab_amgn_FourPointOneZeroPercentNotesDue2021Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Four Point One Zero Percent Notes Due 2021 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointOneZeroPercentNotesDue2021Member" xlink:href="amgn-20210930.xsd#amgn_FourPointOneZeroPercentNotesDue2021Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPointOneZeroPercentNotesDue2021Member" xlink:to="lab_amgn_FourPointOneZeroPercentNotesDue2021Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueInputsLevel3Member_f4e69e6a-54d3-4038-a9c2-bd35727b9d5a_verboseLabel_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel3Member" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Significant unobservable inputs (Level 3) [Member]</link:label>
    <link:label id="lab_us-gaap_FairValueInputsLevel3Member_label_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel3Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, Inputs, Level 3 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel3Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueInputsLevel3Member" xlink:to="lab_us-gaap_FairValueInputsLevel3Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PaymentsOfDividendsCommonStock_70bd7dd1-1edb-4494-8d8a-12ab1cd9b372_negatedLabel_en-US" xlink:label="lab_us-gaap_PaymentsOfDividendsCommonStock" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Dividends paid</link:label>
    <link:label id="lab_us-gaap_PaymentsOfDividendsCommonStock_label_en-US" xlink:label="lab_us-gaap_PaymentsOfDividendsCommonStock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Payments of Ordinary Dividends, Common Stock</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDividendsCommonStock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsOfDividendsCommonStock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PaymentsOfDividendsCommonStock" xlink:to="lab_us-gaap_PaymentsOfDividendsCommonStock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InventoryDisclosureTextBlock_bce9c937-fd52-448c-adc2-e9fcfceb306a_verboseLabel_en-US" xlink:label="lab_us-gaap_InventoryDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Inventories</link:label>
    <link:label id="lab_us-gaap_InventoryDisclosureTextBlock_label_en-US" xlink:label="lab_us-gaap_InventoryDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Inventory Disclosure [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryDisclosureTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InventoryDisclosureTextBlock" xlink:to="lab_us-gaap_InventoryDisclosureTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity_8e911dbc-5f5b-4378-90e2-1eea23bc1f6f_terseLabel_en-US" xlink:label="lab_us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investment, Difference Between Carrying Amount and Underlying Equity</link:label>
    <link:label id="lab_us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity_label_en-US" xlink:label="lab_us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investment, Difference Between Carrying Amount and Underlying Equity</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity" xlink:to="lab_us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccountingPoliciesAbstract_4a0234ac-5928-45b7-9fc9-d57fa678cdf9_terseLabel_en-US" xlink:label="lab_us-gaap_AccountingPoliciesAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accounting Policies [Abstract]</link:label>
    <link:label id="lab_us-gaap_AccountingPoliciesAbstract_label_en-US" xlink:label="lab_us-gaap_AccountingPoliciesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accounting Policies [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccountingPoliciesAbstract" xlink:to="lab_us-gaap_AccountingPoliciesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ForeignGovernmentDebtSecuritiesMember_ad1b8ca3-c03f-4f62-9fc2-6a2df06fafaa_terseLabel_en-US" xlink:label="lab_us-gaap_ForeignGovernmentDebtSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other government-related debt securities - Foreign and other [Member]</link:label>
    <link:label id="lab_us-gaap_ForeignGovernmentDebtSecuritiesMember_label_en-US" xlink:label="lab_us-gaap_ForeignGovernmentDebtSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Security, Government, Non-US [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignGovernmentDebtSecuritiesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember" xlink:to="lab_us-gaap_ForeignGovernmentDebtSecuritiesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeInstrumentRiskAxis_2b260d97-4663-4930-a0ba-fcad07739790_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentRiskAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instrument [Axis]</link:label>
    <link:label id="lab_us-gaap_DerivativeInstrumentRiskAxis_label_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentRiskAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instrument [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis" xlink:to="lab_us-gaap_DerivativeInstrumentRiskAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_SixPointFourZeroPercentNotesDue2039Member_3621a109-34aa-436e-bf94-43c3d4517e6c_terseLabel_en-US" xlink:label="lab_amgn_SixPointFourZeroPercentNotesDue2039Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">6.40% notes due 2039 (6.40% 2039 Notes) [Member]</link:label>
    <link:label id="lab_amgn_SixPointFourZeroPercentNotesDue2039Member_label_en-US" xlink:label="lab_amgn_SixPointFourZeroPercentNotesDue2039Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Six Point Four Zero Percent Notes Due 2039 [Member]</link:label>
    <link:label id="lab_amgn_SixPointFourZeroPercentNotesDue2039Member_documentation_en-US" xlink:label="lab_amgn_SixPointFourZeroPercentNotesDue2039Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Six Point Four Zero Percent Notes Due 2039 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_SixPointFourZeroPercentNotesDue2039Member" xlink:href="amgn-20210930.xsd#amgn_SixPointFourZeroPercentNotesDue2039Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_SixPointFourZeroPercentNotesDue2039Member" xlink:to="lab_amgn_SixPointFourZeroPercentNotesDue2039Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NonoperatingIncomeExpense_a7545011-f5fa-4130-8b38-51106cf71dbc_terseLabel_en-US" xlink:label="lab_us-gaap_NonoperatingIncomeExpense" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other income, net</link:label>
    <link:label id="lab_us-gaap_NonoperatingIncomeExpense_label_en-US" xlink:label="lab_us-gaap_NonoperatingIncomeExpense" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Nonoperating Income (Expense)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NonoperatingIncomeExpense"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NonoperatingIncomeExpense" xlink:to="lab_us-gaap_NonoperatingIncomeExpense" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_GainContingencyPatentsFoundInfringedUponNumber_de87afd7-8a10-4c74-8f67-53d0153c8fc8_terseLabel_en-US" xlink:label="lab_us-gaap_GainContingencyPatentsFoundInfringedUponNumber" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Gain Contingency, Patents Found Infringed upon, Number</link:label>
    <link:label id="lab_us-gaap_GainContingencyPatentsFoundInfringedUponNumber_label_en-US" xlink:label="lab_us-gaap_GainContingencyPatentsFoundInfringedUponNumber" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Gain Contingency, Patents Found Infringed upon, Number</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainContingencyPatentsFoundInfringedUponNumber" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GainContingencyPatentsFoundInfringedUponNumber"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_GainContingencyPatentsFoundInfringedUponNumber" xlink:to="lab_us-gaap_GainContingencyPatentsFoundInfringedUponNumber" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommitmentsAndContingencies_5d32bc6d-a0bf-42f6-b46e-cfae50b04dfb_verboseLabel_en-US" xlink:label="lab_us-gaap_CommitmentsAndContingencies" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Contingencies and commitments</link:label>
    <link:label id="lab_us-gaap_CommitmentsAndContingencies_label_en-US" xlink:label="lab_us-gaap_CommitmentsAndContingencies" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Commitments and Contingencies</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommitmentsAndContingencies" xlink:to="lab_us-gaap_CommitmentsAndContingencies" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SubsequentEventTable_682305aa-6fda-4c3a-a427-b1927eb16879_terseLabel_en-US" xlink:label="lab_us-gaap_SubsequentEventTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Subsequent Event [Table]</link:label>
    <link:label id="lab_us-gaap_SubsequentEventTable_label_en-US" xlink:label="lab_us-gaap_SubsequentEventTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Subsequent Event [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SubsequentEventTable" xlink:to="lab_us-gaap_SubsequentEventTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_241f656b-047e-4c64-b3f1-504a35f86850_verboseLabel_en-US" xlink:label="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated other comprehensive loss</link:label>
    <link:label id="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_label_en-US" xlink:label="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated Other Comprehensive Income (Loss), Net of Tax</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:to="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent_821014bf-43d1-4cc5-b3b9-6055bcd60e14_terseLabel_en-US" xlink:label="lab_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other</link:label>
    <link:label id="lab_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent_label_en-US" xlink:label="lab_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Comprehensive Income (Loss), Other Gains (Losses), Net of Tax, Portion Attributable to Parent</link:label>
    <link:label id="lab_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent_documentation_en-US" xlink:label="lab_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Comprehensive Income (Loss), Other Gains (Losses), Net of Tax, Portion Attributable to Parent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent" xlink:href="amgn-20210930.xsd#amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent" xlink:to="lab_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember_535aeb59-00b4-4ff6-8a13-12f09f654234_terseLabel_en-US" xlink:label="lab_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Seven Seven Percent Notes Due Two Zero Five Three</link:label>
    <link:label id="lab_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember_label_en-US" xlink:label="lab_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Seven Seven Percent Notes Due Two Zero Five Three [Member]</link:label>
    <link:label id="lab_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember_documentation_en-US" xlink:label="lab_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Seven Seven Percent Notes Due Two Zero Five Three</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember" xlink:href="amgn-20210930.xsd#amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember" xlink:to="lab_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_KANJINTIPatentLitigationMember_86fa4222-5393-43e3-a067-ccf42a0d9f20_terseLabel_en-US" xlink:label="lab_amgn_KANJINTIPatentLitigationMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">KANJINTI Patent Litigation [Member]</link:label>
    <link:label id="lab_amgn_KANJINTIPatentLitigationMember_label_en-US" xlink:label="lab_amgn_KANJINTIPatentLitigationMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">KANJINTI Patent Litigation [Member]</link:label>
    <link:label id="lab_amgn_KANJINTIPatentLitigationMember_documentation_en-US" xlink:label="lab_amgn_KANJINTIPatentLitigationMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">KANJINTI Patent Litigation [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_KANJINTIPatentLitigationMember" xlink:href="amgn-20210930.xsd#amgn_KANJINTIPatentLitigationMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_KANJINTIPatentLitigationMember" xlink:to="lab_amgn_KANJINTIPatentLitigationMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_66b7111b-840e-47dc-babe-f46ee9da9168_terseLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Residential-mortgage-backed securities</link:label>
    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_label_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale, Maturity, without Single Maturity Date, Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue" xlink:to="lab_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract_4374009c-c227-4dd9-afdb-52a7868193bd_verboseLabel_en-US" xlink:label="lab_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair values of available-for-sale investments by classification in the Consolidated Balance Sheets</link:label>
    <link:label id="lab_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract_label_en-US" xlink:label="lab_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Values Of Available For Sale Investments By Classification In Consolidated Balance Sheets [Abstract]</link:label>
    <link:label id="lab_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract_documentation_en-US" xlink:label="lab_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair values of available-for-sale investments by classification in the Consolidated Balance Sheets.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract" xlink:href="amgn-20210930.xsd#amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract" xlink:to="lab_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_BusinessCombinationDisclosureTextBlock_a4e87454-e6d5-4e91-9ab7-72c8ee98ccbf_terseLabel_en-US" xlink:label="lab_us-gaap_BusinessCombinationDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Combination Disclosure [Text Block]</link:label>
    <link:label id="lab_us-gaap_BusinessCombinationDisclosureTextBlock_label_en-US" xlink:label="lab_us-gaap_BusinessCombinationDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Combination Disclosure [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationDisclosureTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationDisclosureTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BusinessCombinationDisclosureTextBlock" xlink:to="lab_us-gaap_BusinessCombinationDisclosureTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfInterestRateDerivativesTableTextBlock_78703154-8fc1-42c5-ab69-57b09499a188_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfInterestRateDerivativesTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of interest rate swaps</link:label>
    <link:label id="lab_us-gaap_ScheduleOfInterestRateDerivativesTableTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfInterestRateDerivativesTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Interest Rate Derivatives [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInterestRateDerivativesTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfInterestRateDerivativesTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfInterestRateDerivativesTableTextBlock" xlink:to="lab_us-gaap_ScheduleOfInterestRateDerivativesTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_5ad2ea57-2014-4f85-93d5-e50696142a6c_terseLabel_en-US" xlink:label="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification out of Accumulated Other Comprehensive Income [Axis]</link:label>
    <link:label id="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_label_en-US" xlink:label="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification out of Accumulated Other Comprehensive Income [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis" xlink:to="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_DocumentPeriodEndDate_60a54f9b-c23f-4e57-8aae-e95e293365fd_terseLabel_en-US" xlink:label="lab_dei_DocumentPeriodEndDate" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Period End Date</link:label>
    <link:label id="lab_dei_DocumentPeriodEndDate_label_en-US" xlink:label="lab_dei_DocumentPeriodEndDate" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Period End Date</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentPeriodEndDate"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_DocumentPeriodEndDate" xlink:to="lab_dei_DocumentPeriodEndDate" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock_9a37ff2c-5a27-4c65-96cc-d8ac64521d5c_verboseLabel_en-US" xlink:label="lab_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments</link:label>
    <link:label id="lab_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock_label_en-US" xlink:label="lab_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock" xlink:to="lab_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LossContingencyClaimsSettledNumber_2ed35533-d872-476e-80a4-da86bf11d34a_terseLabel_en-US" xlink:label="lab_us-gaap_LossContingencyClaimsSettledNumber" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, Claims Settled, Number</link:label>
    <link:label id="lab_us-gaap_LossContingencyClaimsSettledNumber_label_en-US" xlink:label="lab_us-gaap_LossContingencyClaimsSettledNumber" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, Claims Settled, Number</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyClaimsSettledNumber" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyClaimsSettledNumber"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LossContingencyClaimsSettledNumber" xlink:to="lab_us-gaap_LossContingencyClaimsSettledNumber" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CostsAndExpenses_bbec9c3a-7bdb-4d28-87eb-29cc8feaf221_totalLabel_en-US" xlink:label="lab_us-gaap_CostsAndExpenses" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total operating expenses</link:label>
    <link:label id="lab_us-gaap_CostsAndExpenses_label_en-US" xlink:label="lab_us-gaap_CostsAndExpenses" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Costs and Expenses</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostsAndExpenses"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CostsAndExpenses" xlink:to="lab_us-gaap_CostsAndExpenses" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StatementClassOfStockAxis_eb9565ca-dc15-4125-b5f9-30de8f86e429_terseLabel_en-US" xlink:label="lab_us-gaap_StatementClassOfStockAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Class of Stock [Axis]</link:label>
    <link:label id="lab_us-gaap_StatementClassOfStockAxis_label_en-US" xlink:label="lab_us-gaap_StatementClassOfStockAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Class of Stock [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StatementClassOfStockAxis" xlink:to="lab_us-gaap_StatementClassOfStockAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityRegistrantName_0b18f509-a52e-4bef-a7df-c01ab7a447ff_terseLabel_en-US" xlink:label="lab_dei_EntityRegistrantName" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Registrant Name</link:label>
    <link:label id="lab_dei_EntityRegistrantName_label_en-US" xlink:label="lab_dei_EntityRegistrantName" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Registrant Name</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityRegistrantName"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityRegistrantName" xlink:to="lab_dei_EntityRegistrantName" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_RecoveryOfDirectCostsReceivable_18050c33-2cb4-4c69-a68c-567cf919e9f1_terseLabel_en-US" xlink:label="lab_amgn_RecoveryOfDirectCostsReceivable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Receivable for direct costs owed</link:label>
    <link:label id="lab_amgn_RecoveryOfDirectCostsReceivable_label_en-US" xlink:label="lab_amgn_RecoveryOfDirectCostsReceivable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Recovery Of Direct Costs, Receivable</link:label>
    <link:label id="lab_amgn_RecoveryOfDirectCostsReceivable_documentation_en-US" xlink:label="lab_amgn_RecoveryOfDirectCostsReceivable" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Recovery Of Direct Costs, Receivable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_RecoveryOfDirectCostsReceivable" xlink:href="amgn-20210930.xsd#amgn_RecoveryOfDirectCostsReceivable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_RecoveryOfDirectCostsReceivable" xlink:to="lab_amgn_RecoveryOfDirectCostsReceivable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TypeOfArrangementAxis_1946740d-c777-4df2-b200-d9ac4507eb74_terseLabel_en-US" xlink:label="lab_us-gaap_TypeOfArrangementAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Collaborative Arrangement and Arrangement Other than Collaborative [Axis]</link:label>
    <link:label id="lab_us-gaap_TypeOfArrangementAxis_label_en-US" xlink:label="lab_us-gaap_TypeOfArrangementAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Collaborative Arrangement and Arrangement Other than Collaborative [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfArrangementAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TypeOfArrangementAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TypeOfArrangementAxis" xlink:to="lab_us-gaap_TypeOfArrangementAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_currency_GBP_f2b97c65-b402-4d76-8853-05c64f067344_terseLabel_en-US" xlink:label="lab_currency_GBP" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">United Kingdom, Pounds</link:label>
    <link:label id="lab_currency_GBP_label_en-US" xlink:label="lab_currency_GBP" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">United Kingdom, Pounds</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_currency_GBP" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_GBP"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_currency_GBP" xlink:to="lab_currency_GBP" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_NumberOfAssertedPatents_f59ac19e-e9f7-4390-ada9-bf77c0e6ebf4_terseLabel_en-US" xlink:label="lab_amgn_NumberOfAssertedPatents" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Number Of Asserted Patents</link:label>
    <link:label id="lab_amgn_NumberOfAssertedPatents_label_en-US" xlink:label="lab_amgn_NumberOfAssertedPatents" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Number Of Asserted Patents</link:label>
    <link:label id="lab_amgn_NumberOfAssertedPatents_documentation_en-US" xlink:label="lab_amgn_NumberOfAssertedPatents" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Number Of Asserted Patents</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_NumberOfAssertedPatents" xlink:href="amgn-20210930.xsd#amgn_NumberOfAssertedPatents"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_NumberOfAssertedPatents" xlink:to="lab_amgn_NumberOfAssertedPatents" xlink:type="arc" order="1"/>
    <link:label id="lab_exch_XNGS_f742234e-1cd8-4e55-99cd-cbf066d6f4d8_terseLabel_en-US" xlink:label="lab_exch_XNGS" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">The NASDAQ Global Select Market [Member]</link:label>
    <link:label id="lab_exch_XNGS_label_en-US" xlink:label="lab_exch_XNGS" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">NASDAQ/NGS (GLOBAL SELECT MARKET) [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_exch_XNGS" xlink:href="https://xbrl.sec.gov/exch/2021/exch-2021.xsd#exch_XNGS"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_exch_XNGS" xlink:to="lab_exch_XNGS" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InventoryWorkInProcessNetOfReserves_ebc5e6d1-12fd-4b0e-8d3b-223300f9b257_verboseLabel_en-US" xlink:label="lab_us-gaap_InventoryWorkInProcessNetOfReserves" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Work in process</link:label>
    <link:label id="lab_us-gaap_InventoryWorkInProcessNetOfReserves_label_en-US" xlink:label="lab_us-gaap_InventoryWorkInProcessNetOfReserves" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Inventory, Work in Process, Net of Reserves</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryWorkInProcessNetOfReserves" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryWorkInProcessNetOfReserves"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InventoryWorkInProcessNetOfReserves" xlink:to="lab_us-gaap_InventoryWorkInProcessNetOfReserves" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_Cash_83a5c490-a0cb-46c1-b40d-d252b03ab7ad_verboseLabel_en-US" xlink:label="lab_us-gaap_Cash" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash</link:label>
    <link:label id="lab_us-gaap_Cash_label_en-US" xlink:label="lab_us-gaap_Cash" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Cash" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Cash"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_Cash" xlink:to="lab_us-gaap_Cash" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FinancialInstrumentAxis_2f8bbfc2-57de-4dcc-b071-2101261b2534_terseLabel_en-US" xlink:label="lab_us-gaap_FinancialInstrumentAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Instrument [Axis]</link:label>
    <link:label id="lab_us-gaap_FinancialInstrumentAxis_label_en-US" xlink:label="lab_us-gaap_FinancialInstrumentAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Instrument [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FinancialInstrumentAxis" xlink:to="lab_us-gaap_FinancialInstrumentAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FivePrimeTherapeuticsIncMember_47dd9a56-8743-4907-ae25-dcded71b328c_terseLabel_en-US" xlink:label="lab_amgn_FivePrimeTherapeuticsIncMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Five Prime Therapeutics, Inc.</link:label>
    <link:label id="lab_amgn_FivePrimeTherapeuticsIncMember_label_en-US" xlink:label="lab_amgn_FivePrimeTherapeuticsIncMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Five Prime Therapeutics, Inc. [Member]</link:label>
    <link:label id="lab_amgn_FivePrimeTherapeuticsIncMember_documentation_en-US" xlink:label="lab_amgn_FivePrimeTherapeuticsIncMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Five Prime Therapeutics, Inc.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePrimeTherapeuticsIncMember" xlink:href="amgn-20210930.xsd#amgn_FivePrimeTherapeuticsIncMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FivePrimeTherapeuticsIncMember" xlink:to="lab_amgn_FivePrimeTherapeuticsIncMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommonStockDividendsPerShareDeclared_2057c53d-e809-42ab-bc18-7d037f338880_terseLabel_en-US" xlink:label="lab_us-gaap_CommonStockDividendsPerShareDeclared" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock, dividends declared per share (in usd per share)</link:label>
    <link:label id="lab_us-gaap_CommonStockDividendsPerShareDeclared_90a5b23f-2588-4846-945a-a34cc1d71c78_verboseLabel_en-US" xlink:label="lab_us-gaap_CommonStockDividendsPerShareDeclared" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Dividends declared per share (in usd per share)</link:label>
    <link:label id="lab_us-gaap_CommonStockDividendsPerShareDeclared_label_en-US" xlink:label="lab_us-gaap_CommonStockDividendsPerShareDeclared" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common Stock, Dividends, Per Share, Declared</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockDividendsPerShareDeclared" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockDividendsPerShareDeclared"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommonStockDividendsPerShareDeclared" xlink:to="lab_us-gaap_CommonStockDividendsPerShareDeclared" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccruedLiabilitiesCurrent_99abacb5-5635-46e6-8a38-0f5105396f4b_verboseLabel_en-US" xlink:label="lab_us-gaap_AccruedLiabilitiesCurrent" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued liabilities</link:label>
    <link:label id="lab_us-gaap_AccruedLiabilitiesCurrent_label_en-US" xlink:label="lab_us-gaap_AccruedLiabilitiesCurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Liabilities, Current</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent" xlink:to="lab_us-gaap_AccruedLiabilitiesCurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_e96f0447-79d0-4ac0-8009-1569f7ce5937_terseLabel_en-US" xlink:label="lab_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total revenues</link:label>
    <link:label id="lab_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_label_en-US" xlink:label="lab_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Revenue from Contract with Customer, Excluding Assessed Tax</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:to="lab_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross_228c4096-02d9-4b42-992a-01c8ed6776ad_terseLabel_en-US" xlink:label="lab_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Global research and development costs (up to)</link:label>
    <link:label id="lab_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross_label_en-US" xlink:label="lab_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Research and Development Arrangement, Contract to Perform for Others, Costs Incurred, Gross</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross" xlink:to="lab_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InventoryFinishedGoodsNetOfReserves_834deb40-e441-4e91-9e93-236873aaca1c_verboseLabel_en-US" xlink:label="lab_us-gaap_InventoryFinishedGoodsNetOfReserves" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finished goods</link:label>
    <link:label id="lab_us-gaap_InventoryFinishedGoodsNetOfReserves_label_en-US" xlink:label="lab_us-gaap_InventoryFinishedGoodsNetOfReserves" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Inventory, Finished Goods, Net of Reserves</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryFinishedGoodsNetOfReserves" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryFinishedGoodsNetOfReserves"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InventoryFinishedGoodsNetOfReserves" xlink:to="lab_us-gaap_InventoryFinishedGoodsNetOfReserves" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_e9824201-2ebe-4d21-84bf-396f64053452_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Available-for-sale Securities [Table]</link:label>
    <link:label id="lab_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_label_en-US" xlink:label="lab_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Available-for-sale Securities [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable" xlink:to="lab_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EquityAbstract_9b368e4a-18b2-4512-8832-c54835626ee0_terseLabel_en-US" xlink:label="lab_us-gaap_EquityAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity [Abstract]</link:label>
    <link:label id="lab_us-gaap_EquityAbstract_label_en-US" xlink:label="lab_us-gaap_EquityAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EquityAbstract" xlink:to="lab_us-gaap_EquityAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis_db67c5a8-f878-47a0-8cd9-e6ad4c88d543_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Hierarchy and NAV [Axis]</link:label>
    <link:label id="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis_label_en-US" xlink:label="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Hierarchy and NAV [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:to="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommonStockMember_ce6ddc3e-3c7d-4afb-bfd8-ee954d3a593e_terseLabel_en-US" xlink:label="lab_us-gaap_CommonStockMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common Stock [Member]</link:label>
    <link:label id="lab_us-gaap_CommonStockMember_5b633312-0261-486a-990a-81db7f1faf6b_verboseLabel_en-US" xlink:label="lab_us-gaap_CommonStockMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Number of shares of common stock [Member]</link:label>
    <link:label id="lab_us-gaap_CommonStockMember_label_en-US" xlink:label="lab_us-gaap_CommonStockMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common Stock [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommonStockMember" xlink:to="lab_us-gaap_CommonStockMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_VariableRateAxis_1fb83c57-ed42-490f-a30b-f01948148573_terseLabel_en-US" xlink:label="lab_us-gaap_VariableRateAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Variable Rate [Axis]</link:label>
    <link:label id="lab_us-gaap_VariableRateAxis_label_en-US" xlink:label="lab_us-gaap_VariableRateAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Variable Rate [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_VariableRateAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_VariableRateAxis" xlink:to="lab_us-gaap_VariableRateAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_EnbrelMember_f9a5b2ee-0fbd-44f6-93fc-5f9029d6f441_terseLabel_en-US" xlink:label="lab_amgn_EnbrelMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Enbrel&#174; (etanercept) [Member]</link:label>
    <link:label id="lab_amgn_EnbrelMember_label_en-US" xlink:label="lab_amgn_EnbrelMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">ENBREL [Member]</link:label>
    <link:label id="lab_amgn_EnbrelMember_documentation_en-US" xlink:label="lab_amgn_EnbrelMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">ENBREL.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_EnbrelMember" xlink:href="amgn-20210930.xsd#amgn_EnbrelMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_EnbrelMember" xlink:to="lab_amgn_EnbrelMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OperatingIncomeLoss_63ce0436-b91d-4e73-820d-8d80b68f75f1_totalLabel_en-US" xlink:label="lab_us-gaap_OperatingIncomeLoss" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Operating income</link:label>
    <link:label id="lab_us-gaap_OperatingIncomeLoss_label_en-US" xlink:label="lab_us-gaap_OperatingIncomeLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Operating Income (Loss)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OperatingIncomeLoss" xlink:to="lab_us-gaap_OperatingIncomeLoss" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestRateFairValueHedgeAssetAtFairValue_a3f6cb98-3754-4751-8601-d49339c0b42c_terseLabel_en-US" xlink:label="lab_us-gaap_InterestRateFairValueHedgeAssetAtFairValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest rate swap contracts</link:label>
    <link:label id="lab_us-gaap_InterestRateFairValueHedgeAssetAtFairValue_label_en-US" xlink:label="lab_us-gaap_InterestRateFairValueHedgeAssetAtFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Rate Fair Value Hedge Asset at Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateFairValueHedgeAssetAtFairValue" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateFairValueHedgeAssetAtFairValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestRateFairValueHedgeAssetAtFairValue" xlink:to="lab_us-gaap_InterestRateFairValueHedgeAssetAtFairValue" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FivePointOneFivePercentNotesDue2041Member_b0a790e8-9f3a-4a0c-b2f8-62ad68474a4b_terseLabel_en-US" xlink:label="lab_amgn_FivePointOneFivePercentNotesDue2041Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">5.15% notes due 2041 (5.15% 2041 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FivePointOneFivePercentNotesDue2041Member_label_en-US" xlink:label="lab_amgn_FivePointOneFivePercentNotesDue2041Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Five Point One Five Percent Notes Due 2041 [Member]</link:label>
    <link:label id="lab_amgn_FivePointOneFivePercentNotesDue2041Member_documentation_en-US" xlink:label="lab_amgn_FivePointOneFivePercentNotesDue2041Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Five Point One Five Percent Notes Due 2041 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointOneFivePercentNotesDue2041Member" xlink:href="amgn-20210930.xsd#amgn_FivePointOneFivePercentNotesDue2041Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FivePointOneFivePercentNotesDue2041Member" xlink:to="lab_amgn_FivePointOneFivePercentNotesDue2041Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_d9026f31-d83a-4106-9cfe-40e198264270_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale [Line Items]</link:label>
    <link:label id="lab_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_label_en-US" xlink:label="lab_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems" xlink:to="lab_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_b84cf207-44c6-4a71-98d5-b342a1b36277_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Gross unrealized losses</link:label>
    <link:label id="lab_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_label_en-US" xlink:label="lab_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale, Accumulated Gross Unrealized Loss, before Tax</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" xlink:to="lab_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_ba410147-67e6-4d4f-8728-8b525f0680ae_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total estimated amortization of finite-lived intangible assets for 2023</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Year Two</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CollaborativeArrangementDisclosureTextBlock_11bda9e9-a180-4f25-92f5-046e11389308_terseLabel_en-US" xlink:label="lab_us-gaap_CollaborativeArrangementDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Collaborations</link:label>
    <link:label id="lab_us-gaap_CollaborativeArrangementDisclosureTextBlock_label_en-US" xlink:label="lab_us-gaap_CollaborativeArrangementDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Collaborative Arrangement Disclosure [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CollaborativeArrangementDisclosureTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock" xlink:to="lab_us-gaap_CollaborativeArrangementDisclosureTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_HedgingDesignationAxis_9559f47b-7c91-4773-8bef-f9cb5544e4eb_terseLabel_en-US" xlink:label="lab_us-gaap_HedgingDesignationAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedging Designation [Axis]</link:label>
    <link:label id="lab_us-gaap_HedgingDesignationAxis_label_en-US" xlink:label="lab_us-gaap_HedgingDesignationAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedging Designation [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingDesignationAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_HedgingDesignationAxis" xlink:to="lab_us-gaap_HedgingDesignationAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_9acd47fa-bb87-49ab-a456-71f39060be1a_terseLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) in Stockholders' Equity [Roll Forward]</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_509a5c7e-2979-493c-81d9-556188acf797_verboseLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) in AOCI [Roll Forward]</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) in Stockholders' Equity [Roll Forward]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward" xlink:to="lab_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LongTermDebtMember_ed770dce-158b-4129-9228-7c665826d626_terseLabel_en-US" xlink:label="lab_us-gaap_LongTermDebtMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term debt [Member]</link:label>
    <link:label id="lab_us-gaap_LongTermDebtMember_label_en-US" xlink:label="lab_us-gaap_LongTermDebtMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term Debt [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LongTermDebtMember" xlink:to="lab_us-gaap_LongTermDebtMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_VariableRateDomain_db5ae883-51fd-41c7-8ce4-13ee0babd8cc_terseLabel_en-US" xlink:label="lab_us-gaap_VariableRateDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Variable Rate [Domain]</link:label>
    <link:label id="lab_us-gaap_VariableRateDomain_label_en-US" xlink:label="lab_us-gaap_VariableRateDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Variable Rate [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_VariableRateDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_VariableRateDomain" xlink:to="lab_us-gaap_VariableRateDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CashAndCashEquivalentsAtCarryingValue_c424c429-092d-42a5-b277-2d4acd69cd6c_verboseLabel_en-US" xlink:label="lab_us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash and cash equivalents</link:label>
    <link:label id="lab_us-gaap_CashAndCashEquivalentsAtCarryingValue_label_en-US" xlink:label="lab_us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash and Cash Equivalents, at Carrying Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:to="lab_us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FloatingRateNotesDue2020Member_ecf2ea1c-18af-4d47-b4a8-f8af191356b3_terseLabel_en-US" xlink:label="lab_amgn_FloatingRateNotesDue2020Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Floating Rate Notes Due 2020 [Member]</link:label>
    <link:label id="lab_amgn_FloatingRateNotesDue2020Member_label_en-US" xlink:label="lab_amgn_FloatingRateNotesDue2020Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Floating Rate Notes Due 2020 [Member]</link:label>
    <link:label id="lab_amgn_FloatingRateNotesDue2020Member_documentation_en-US" xlink:label="lab_amgn_FloatingRateNotesDue2020Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Floating Rate Notes Due 2020 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FloatingRateNotesDue2020Member" xlink:href="amgn-20210930.xsd#amgn_FloatingRateNotesDue2020Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FloatingRateNotesDue2020Member" xlink:to="lab_amgn_FloatingRateNotesDue2020Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_743ed9df-efa1-454b-8612-b065ed181a06_terseLabel_en-US" xlink:label="lab_us-gaap_LitigationSettlementAmountAwardedFromOtherParty" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amount received from settlement</link:label>
    <link:label id="lab_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_label_en-US" xlink:label="lab_us-gaap_LitigationSettlementAmountAwardedFromOtherParty" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Litigation Settlement, Amount Awarded from Other Party</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LitigationSettlementAmountAwardedFromOtherParty" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LitigationSettlementAmountAwardedFromOtherParty"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LitigationSettlementAmountAwardedFromOtherParty" xlink:to="lab_us-gaap_LitigationSettlementAmountAwardedFromOtherParty" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1_07429e32-b7fd-49ed-bd02-b07abbd0a4ea_terseLabel_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income taxes</link:label>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1_label_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Comprehensive Income (Loss), Tax, Portion Attributable to Parent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" xlink:to="lab_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommonStockDividendsPerShareCashPaid_95ff40d8-c2fb-4be9-94d5-d6970042ab54_terseLabel_en-US" xlink:label="lab_us-gaap_CommonStockDividendsPerShareCashPaid" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Dividends paid per share (in usd per share)</link:label>
    <link:label id="lab_us-gaap_CommonStockDividendsPerShareCashPaid_label_en-US" xlink:label="lab_us-gaap_CommonStockDividendsPerShareCashPaid" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common Stock, Dividends, Per Share, Cash Paid</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockDividendsPerShareCashPaid" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockDividendsPerShareCashPaid"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommonStockDividendsPerShareCashPaid" xlink:to="lab_us-gaap_CommonStockDividendsPerShareCashPaid" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LongtermDebtTypeDomain_010234a9-9d2c-4ece-9656-38e36fb0bc58_terseLabel_en-US" xlink:label="lab_us-gaap_LongtermDebtTypeDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term Debt, Type [Domain]</link:label>
    <link:label id="lab_us-gaap_LongtermDebtTypeDomain_label_en-US" xlink:label="lab_us-gaap_LongtermDebtTypeDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term Debt, Type [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LongtermDebtTypeDomain" xlink:to="lab_us-gaap_LongtermDebtTypeDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ArrangementsAndNonarrangementTransactionsMember_dfbd5125-28fc-41c9-9cda-0cc4fe016639_terseLabel_en-US" xlink:label="lab_us-gaap_ArrangementsAndNonarrangementTransactionsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Collaborative Arrangement and Arrangement Other than Collaborative [Domain]</link:label>
    <link:label id="lab_us-gaap_ArrangementsAndNonarrangementTransactionsMember_label_en-US" xlink:label="lab_us-gaap_ArrangementsAndNonarrangementTransactionsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Collaborative Arrangement and Arrangement Other than Collaborative [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember" xlink:to="lab_us-gaap_ArrangementsAndNonarrangementTransactionsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeNotionalAmount_02d4dbd3-5050-4458-94b6-aed1fc75bd81_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeNotionalAmount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Notional amounts</link:label>
    <link:label id="lab_us-gaap_DerivativeNotionalAmount_4ed53a00-79af-4546-b4b7-b4fbcd580bf6_verboseLabel_en-US" xlink:label="lab_us-gaap_DerivativeNotionalAmount" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative, notional amount</link:label>
    <link:label id="lab_us-gaap_DerivativeNotionalAmount_label_en-US" xlink:label="lab_us-gaap_DerivativeNotionalAmount" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative, Notional Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeNotionalAmount" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeNotionalAmount"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeNotionalAmount" xlink:to="lab_us-gaap_DerivativeNotionalAmount" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_b69ae708-87a9-48b4-8cdb-5604b328ec54_verboseLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other liabilities</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) in Other Operating Liabilities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingLiabilities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xlink:to="lab_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_eba0a361-0ee4-4d28-88af-d68a48d3cb94_terseLabel_en-US" xlink:label="lab_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Acquired in-process research and development</link:label>
    <link:label id="lab_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_label_en-US" xlink:label="lab_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Research and Development Asset Acquired Other than Through Business Combination, Written-off</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff" xlink:to="lab_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_e1c9c081-ce21-45f4-8673-57833797a38c_negatedLabel_en-US" xlink:label="lab_us-gaap_PaymentsForProceedsFromOtherInvestingActivities" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other</link:label>
    <link:label id="lab_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_label_en-US" xlink:label="lab_us-gaap_PaymentsForProceedsFromOtherInvestingActivities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Payments for (Proceeds from) Other Investing Activities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsForProceedsFromOtherInvestingActivities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities" xlink:to="lab_us-gaap_PaymentsForProceedsFromOtherInvestingActivities" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares_8ac98f1c-aaf3-4760-9add-d628d1be20e5_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Repurchases of common stock, Shares</link:label>
    <link:label id="lab_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares_label_en-US" xlink:label="lab_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock Repurchased and Retired During Period, Shares</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchasedAndRetiredDuringPeriodShares"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares" xlink:to="lab_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_3a53dc1c-b23a-4282-9458-509a4e6b1acb_negatedLabel_en-US" xlink:label="lab_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Purchases of property, plant and equipment</link:label>
    <link:label id="lab_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_label_en-US" xlink:label="lab_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Payments to Acquire Property, Plant, and Equipment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:to="lab_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_MaximumMember_bf7e16f9-3ced-425d-999d-29af7b56981b_terseLabel_en-US" xlink:label="lab_srt_MaximumMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maximum [Member]</link:label>
    <link:label id="lab_srt_MaximumMember_label_en-US" xlink:label="lab_srt_MaximumMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maximum [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MaximumMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_MaximumMember" xlink:to="lab_srt_MaximumMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ThreePointTwoZeroNotesDue2027Member_f90a78ad-c9fc-42a3-9f5e-8c5ac0b9bbf7_terseLabel_en-US" xlink:label="lab_amgn_ThreePointTwoZeroNotesDue2027Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">3.20% notes due 2027 (3.20% 2027 Notes) [Member]</link:label>
    <link:label id="lab_amgn_ThreePointTwoZeroNotesDue2027Member_label_en-US" xlink:label="lab_amgn_ThreePointTwoZeroNotesDue2027Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point Two Zero Notes Due 2027 [Member]</link:label>
    <link:label id="lab_amgn_ThreePointTwoZeroNotesDue2027Member_documentation_en-US" xlink:label="lab_amgn_ThreePointTwoZeroNotesDue2027Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point Two Zero Notes Due 2027 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointTwoZeroNotesDue2027Member" xlink:href="amgn-20210930.xsd#amgn_ThreePointTwoZeroNotesDue2027Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ThreePointTwoZeroNotesDue2027Member" xlink:to="lab_amgn_ThreePointTwoZeroNotesDue2027Member" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityInformationLineItems_c8e9e1d1-2069-403d-a5a9-b1203fd41c3a_terseLabel_en-US" xlink:label="lab_dei_EntityInformationLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Information [Line Items]</link:label>
    <link:label id="lab_dei_EntityInformationLineItems_label_en-US" xlink:label="lab_dei_EntityInformationLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Information [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInformationLineItems" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityInformationLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityInformationLineItems" xlink:to="lab_dei_EntityInformationLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LossContingencyNatureDomain_41584682-bfce-4edf-b6f0-c05111268d4a_terseLabel_en-US" xlink:label="lab_us-gaap_LossContingencyNatureDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, Nature [Domain]</link:label>
    <link:label id="lab_us-gaap_LossContingencyNatureDomain_label_en-US" xlink:label="lab_us-gaap_LossContingencyNatureDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, Nature [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNatureDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyNatureDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LossContingencyNatureDomain" xlink:to="lab_us-gaap_LossContingencyNatureDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_BeiGeneMember_7067a60a-8426-4b7c-89e1-f1237be1e61f_terseLabel_en-US" xlink:label="lab_amgn_BeiGeneMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Collaborative arrangement with BeiGene, Ltd. [Member]</link:label>
    <link:label id="lab_amgn_BeiGeneMember_727ae145-e606-42a4-8bc6-7421ecd95ad6_verboseLabel_en-US" xlink:label="lab_amgn_BeiGeneMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">BeiGene [Member]</link:label>
    <link:label id="lab_amgn_BeiGeneMember_label_en-US" xlink:label="lab_amgn_BeiGeneMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">BeiGene [Member]</link:label>
    <link:label id="lab_amgn_BeiGeneMember_documentation_en-US" xlink:label="lab_amgn_BeiGeneMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">BeiGene [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_BeiGeneMember" xlink:href="amgn-20210930.xsd#amgn_BeiGeneMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_BeiGeneMember" xlink:to="lab_amgn_BeiGeneMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InventoryRawMaterialsNetOfReserves_13fa86bf-67ed-496a-b19d-bb806fb199f2_verboseLabel_en-US" xlink:label="lab_us-gaap_InventoryRawMaterialsNetOfReserves" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Raw materials</link:label>
    <link:label id="lab_us-gaap_InventoryRawMaterialsNetOfReserves_label_en-US" xlink:label="lab_us-gaap_InventoryRawMaterialsNetOfReserves" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Inventory, Raw Materials, Net of Reserves</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryRawMaterialsNetOfReserves" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryRawMaterialsNetOfReserves"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InventoryRawMaterialsNetOfReserves" xlink:to="lab_us-gaap_InventoryRawMaterialsNetOfReserves" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_b7df26e0-2737-4d0a-b31e-264a1bcbe8a9_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total estimated amortization of finite-lived intangible assets for 2022</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Year One</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_RepatriationTaxOnProposedAdditionalTax_015f9f84-a941-43b1-9799-a9e44b122a0c_terseLabel_en-US" xlink:label="lab_amgn_RepatriationTaxOnProposedAdditionalTax" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Repatriation tax on proposed additional tax</link:label>
    <link:label id="lab_amgn_RepatriationTaxOnProposedAdditionalTax_label_en-US" xlink:label="lab_amgn_RepatriationTaxOnProposedAdditionalTax" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Repatriation tax on proposed additional tax</link:label>
    <link:label id="lab_amgn_RepatriationTaxOnProposedAdditionalTax_documentation_en-US" xlink:label="lab_amgn_RepatriationTaxOnProposedAdditionalTax" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Repatriation tax on proposed additional tax</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_RepatriationTaxOnProposedAdditionalTax" xlink:href="amgn-20210930.xsd#amgn_RepatriationTaxOnProposedAdditionalTax"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_RepatriationTaxOnProposedAdditionalTax" xlink:to="lab_amgn_RepatriationTaxOnProposedAdditionalTax" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_NovartisPharmaAGMember_356672bd-9b2f-4323-adf2-97dea9123d69_terseLabel_en-US" xlink:label="lab_amgn_NovartisPharmaAGMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Novartis Pharma AG</link:label>
    <link:label id="lab_amgn_NovartisPharmaAGMember_label_en-US" xlink:label="lab_amgn_NovartisPharmaAGMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Novartis Pharma AG [Member]</link:label>
    <link:label id="lab_amgn_NovartisPharmaAGMember_documentation_en-US" xlink:label="lab_amgn_NovartisPharmaAGMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Novartis Pharma AG</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_NovartisPharmaAGMember" xlink:href="amgn-20210930.xsd#amgn_NovartisPharmaAGMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_NovartisPharmaAGMember" xlink:to="lab_amgn_NovartisPharmaAGMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_818245a0-9766-4178-941b-f467d7f107c2_verboseLabel_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash flows from financing activities:</link:label>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_label_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Cash Provided by (Used in) Financing Activities [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:to="lab_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember_e6c7bfbd-f9b4-4389-883b-575433c37fc2_terseLabel_en-US" xlink:label="lab_amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.20% notes due 2027 (2.20% 2027 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember_label_en-US" xlink:label="lab_amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Two Zero Percent Notes Due Two Zero Two Seven [Member]</link:label>
    <link:label id="lab_amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember_documentation_en-US" xlink:label="lab_amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Two Zero Percent Notes Due Two Zero Two Seven [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember" xlink:href="amgn-20210930.xsd#amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember" xlink:to="lab_amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockholdersEquity_f947914f-ebf5-4671-a7ef-fe26a65dfb88_totalLabel_en-US" xlink:label="lab_us-gaap_StockholdersEquity" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total stockholders&#8217; equity</link:label>
    <link:label id="lab_us-gaap_StockholdersEquity_d2d6baa7-575d-4808-8c9e-fec7400fa868_periodStartLabel_en-US" xlink:label="lab_us-gaap_StockholdersEquity" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Balance as of beginning of period</link:label>
    <link:label id="lab_us-gaap_StockholdersEquity_6e494756-d41e-4815-b65c-65307826a7fc_periodEndLabel_en-US" xlink:label="lab_us-gaap_StockholdersEquity" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Balance as of end of period</link:label>
    <link:label id="lab_us-gaap_StockholdersEquity_label_en-US" xlink:label="lab_us-gaap_StockholdersEquity" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stockholders' Equity Attributable to Parent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockholdersEquity" xlink:to="lab_us-gaap_StockholdersEquity" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DesignatedAsHedgingInstrumentMember_644f1a9f-31c7-4ca6-8ce6-69ec95c91274_verboseLabel_en-US" xlink:label="lab_us-gaap_DesignatedAsHedgingInstrumentMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivatives designated as hedging instrument [Member]</link:label>
    <link:label id="lab_us-gaap_DesignatedAsHedgingInstrumentMember_label_en-US" xlink:label="lab_us-gaap_DesignatedAsHedgingInstrumentMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Designated as Hedging Instrument [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DesignatedAsHedgingInstrumentMember" xlink:to="lab_us-gaap_DesignatedAsHedgingInstrumentMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_TwoPointEightZeroPercent2041NotesMember_0fb7b46d-bc8a-46e5-b09d-fbd48af81691_terseLabel_en-US" xlink:label="lab_amgn_TwoPointEightZeroPercent2041NotesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.80% notes due 2041 (2.80% 2041 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointEightZeroPercent2041NotesMember_label_en-US" xlink:label="lab_amgn_TwoPointEightZeroPercent2041NotesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two point eight zero percent 2041 Notes [Member]</link:label>
    <link:label id="lab_amgn_TwoPointEightZeroPercent2041NotesMember_documentation_en-US" xlink:label="lab_amgn_TwoPointEightZeroPercent2041NotesMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two point eight zero percent 2041 Notes</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointEightZeroPercent2041NotesMember" xlink:href="amgn-20210930.xsd#amgn_TwoPointEightZeroPercent2041NotesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointEightZeroPercent2041NotesMember" xlink:to="lab_amgn_TwoPointEightZeroPercent2041NotesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization_2534a412-7dbd-42db-b211-7e51b15e39fd_negatedLabel_en-US" xlink:label="lab_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated amortization</link:label>
    <link:label id="lab_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization_label_en-US" xlink:label="lab_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Identifiable Intangible Assets Accumulated Amortization</link:label>
    <link:label id="lab_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization_documentation_en-US" xlink:label="lab_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Identifiable intangible assets accumulated amortization.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization" xlink:href="amgn-20210930.xsd#amgn_IdentifiableIntangibleAssetsAccumulatedAmortization"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization" xlink:to="lab_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_8014c5d2-49e9-4d37-a9c4-bf0d1bad3426_terseLabel_en-US" xlink:label="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Goodwill and Intangible Assets Disclosure [Abstract]</link:label>
    <link:label id="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_label_en-US" xlink:label="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Goodwill and Intangible Assets Disclosure [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:to="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss_2297951c-cd46-4910-970e-f1d8c8fbae65_verboseLabel_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total realized losses</link:label>
    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss_label_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale, Realized Loss</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss" xlink:to="lab_us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PaymentsForRepurchaseOfCommonStock_a6a8f7ce-7e60-44f2-9180-9ebad814f141_negatedLabel_en-US" xlink:label="lab_us-gaap_PaymentsForRepurchaseOfCommonStock" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Repurchases of common stock</link:label>
    <link:label id="lab_us-gaap_PaymentsForRepurchaseOfCommonStock_label_en-US" xlink:label="lab_us-gaap_PaymentsForRepurchaseOfCommonStock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Payments for Repurchase of Common Stock</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PaymentsForRepurchaseOfCommonStock" xlink:to="lab_us-gaap_PaymentsForRepurchaseOfCommonStock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockholdersEquityAbstract_efef0bb0-67ec-4a2a-80c3-c889647fef31_verboseLabel_en-US" xlink:label="lab_us-gaap_StockholdersEquityAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stockholders&#8217; equity:</link:label>
    <link:label id="lab_us-gaap_StockholdersEquityAbstract_label_en-US" xlink:label="lab_us-gaap_StockholdersEquityAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stockholders' Equity Attributable to Parent [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquityAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockholdersEquityAbstract" xlink:to="lab_us-gaap_StockholdersEquityAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock_955274ea-ad53-46f1-b703-dd8a5880e31d_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Components of accumulated other comprehensive income</link:label>
    <link:label id="lab_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Accumulated Other Comprehensive Income (Loss) [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:to="lab_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_d59ff15a-378e-40cd-a640-7c0802a9e6c2_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Indefinite-Lived Intangible Assets [Table]</link:label>
    <link:label id="lab_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_label_en-US" xlink:label="lab_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Indefinite-Lived Intangible Assets [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable" xlink:to="lab_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_NeulastaMember_5d3b9d0c-b2d2-45df-b806-fdc0c6599a87_terseLabel_en-US" xlink:label="lab_amgn_NeulastaMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Neulasta&#174; (pegfilgrastim) [Member]</link:label>
    <link:label id="lab_amgn_NeulastaMember_label_en-US" xlink:label="lab_amgn_NeulastaMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Neulasta [Member]</link:label>
    <link:label id="lab_amgn_NeulastaMember_documentation_en-US" xlink:label="lab_amgn_NeulastaMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Neulasta.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_NeulastaMember" xlink:href="amgn-20210930.xsd#amgn_NeulastaMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_NeulastaMember" xlink:to="lab_amgn_NeulastaMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_0044f3ee-8b38-474a-990d-52ec8a4a426c_terseLabel_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Gains (losses) on cash flow hedges</link:label>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_label_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification and Tax, Parent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent" xlink:to="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_BalanceSheetLocationAxis_2198a7d3-f6bd-4702-a3e5-b0cd8e883067_terseLabel_en-US" xlink:label="lab_us-gaap_BalanceSheetLocationAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Balance Sheet Location [Axis]</link:label>
    <link:label id="lab_us-gaap_BalanceSheetLocationAxis_label_en-US" xlink:label="lab_us-gaap_BalanceSheetLocationAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Balance Sheet Location [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BalanceSheetLocationAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BalanceSheetLocationAxis" xlink:to="lab_us-gaap_BalanceSheetLocationAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_AranespMember_1e44a619-bed8-4deb-8f8e-3850ac3f74af_terseLabel_en-US" xlink:label="lab_amgn_AranespMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Aranesp&#174; (darbepoetin alfa) [Member]</link:label>
    <link:label id="lab_amgn_AranespMember_label_en-US" xlink:label="lab_amgn_AranespMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Aranesp [Member]</link:label>
    <link:label id="lab_amgn_AranespMember_documentation_en-US" xlink:label="lab_amgn_AranespMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Aranesp.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AranespMember" xlink:href="amgn-20210930.xsd#amgn_AranespMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_AranespMember" xlink:to="lab_amgn_AranespMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccruedLiabilitiesMember_2bfcaf5f-231f-4957-8d9c-1193e871401d_terseLabel_en-US" xlink:label="lab_us-gaap_AccruedLiabilitiesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued liabilities [Member]</link:label>
    <link:label id="lab_us-gaap_AccruedLiabilitiesMember_label_en-US" xlink:label="lab_us-gaap_AccruedLiabilitiesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Liabilities [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccruedLiabilitiesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccruedLiabilitiesMember" xlink:to="lab_us-gaap_AccruedLiabilitiesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtInstrumentFaceAmount_675af0c2-0f60-4b64-bcbf-4882010b210a_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentFaceAmount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Face amount</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentFaceAmount_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentFaceAmount" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument, Face Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentFaceAmount"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentFaceAmount" xlink:to="lab_us-gaap_DebtInstrumentFaceAmount" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LicensingAgreementsMember_69779df9-2897-4a9c-bb39-3494fa6571d2_terseLabel_en-US" xlink:label="lab_us-gaap_LicensingAgreementsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Licensing Rights [Member]</link:label>
    <link:label id="lab_us-gaap_LicensingAgreementsMember_label_en-US" xlink:label="lab_us-gaap_LicensingAgreementsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Licensing Agreements [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LicensingAgreementsMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LicensingAgreementsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LicensingAgreementsMember" xlink:to="lab_us-gaap_LicensingAgreementsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtInstrumentInterestRateEffectivePercentage_f170415a-5aae-40e7-ae2b-68c5acf69ea0_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Effective interest rate</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentInterestRateEffectivePercentage_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument, Interest Rate, Effective Percentage</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:to="lab_us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_0ea22162-2ca5-4394-a7bf-f296c7566524_terseLabel_en-US" xlink:label="lab_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest rate swap contracts</link:label>
    <link:label id="lab_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_label_en-US" xlink:label="lab_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest Rate Fair Value Hedge Liability at Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue" xlink:to="lab_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_OtherNotesDue2097Member_9f358ad1-3c7b-4a63-8a0b-2c9f5c0b92e6_terseLabel_en-US" xlink:label="lab_amgn_OtherNotesDue2097Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other notes due 2097 [Member]</link:label>
    <link:label id="lab_amgn_OtherNotesDue2097Member_label_en-US" xlink:label="lab_amgn_OtherNotesDue2097Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Notes Due 2097 [Member]</link:label>
    <link:label id="lab_amgn_OtherNotesDue2097Member_documentation_en-US" xlink:label="lab_amgn_OtherNotesDue2097Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Notes Due 2097 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherNotesDue2097Member" xlink:href="amgn-20210930.xsd#amgn_OtherNotesDue2097Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OtherNotesDue2097Member" xlink:to="lab_amgn_OtherNotesDue2097Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LossContingenciesByNatureOfContingencyAxis_f96e02e3-00e7-4e09-bf7a-62d5cd636305_terseLabel_en-US" xlink:label="lab_us-gaap_LossContingenciesByNatureOfContingencyAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency Nature [Axis]</link:label>
    <link:label id="lab_us-gaap_LossContingenciesByNatureOfContingencyAxis_label_en-US" xlink:label="lab_us-gaap_LossContingenciesByNatureOfContingencyAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency Nature [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingenciesByNatureOfContingencyAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis" xlink:to="lab_us-gaap_LossContingenciesByNatureOfContingencyAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ScheduleOfIntangibleAssetsTableTextBlock_265f1afa-5dfb-4652-a3d3-8d9ea23bde9e_terseLabel_en-US" xlink:label="lab_amgn_ScheduleOfIntangibleAssetsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of identifiable intangible assets</link:label>
    <link:label id="lab_amgn_ScheduleOfIntangibleAssetsTableTextBlock_label_en-US" xlink:label="lab_amgn_ScheduleOfIntangibleAssetsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule Of Intangible Assets [Table Text Block]</link:label>
    <link:label id="lab_amgn_ScheduleOfIntangibleAssetsTableTextBlock_documentation_en-US" xlink:label="lab_amgn_ScheduleOfIntangibleAssetsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tabular disclosure of finite-lived and indefinite-lived identifiable intangible assets.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ScheduleOfIntangibleAssetsTableTextBlock" xlink:href="amgn-20210930.xsd#amgn_ScheduleOfIntangibleAssetsTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ScheduleOfIntangibleAssetsTableTextBlock" xlink:to="lab_amgn_ScheduleOfIntangibleAssetsTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_CityAreaCode_206634dd-c737-43b2-bc83-f44dc7f9977b_terseLabel_en-US" xlink:label="lab_dei_CityAreaCode" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">City Area Code</link:label>
    <link:label id="lab_dei_CityAreaCode_label_en-US" xlink:label="lab_dei_CityAreaCode" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">City Area Code</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CityAreaCode"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_CityAreaCode" xlink:to="lab_dei_CityAreaCode" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_RetainedEarningsAccumulatedDeficit_e7584a2e-b589-495b-b694-4125afb40ddb_terseLabel_en-US" xlink:label="lab_us-gaap_RetainedEarningsAccumulatedDeficit" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated deficit</link:label>
    <link:label id="lab_us-gaap_RetainedEarningsAccumulatedDeficit_label_en-US" xlink:label="lab_us-gaap_RetainedEarningsAccumulatedDeficit" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Retained Earnings (Accumulated Deficit)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_RetainedEarningsAccumulatedDeficit" xlink:to="lab_us-gaap_RetainedEarningsAccumulatedDeficit" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_LitigationCaseTypeDomain_310776bf-6d0a-4a46-9bb3-8f87fa5303bb_terseLabel_en-US" xlink:label="lab_srt_LitigationCaseTypeDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Litigation Case [Domain]</link:label>
    <link:label id="lab_srt_LitigationCaseTypeDomain_label_en-US" xlink:label="lab_srt_LitigationCaseTypeDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Litigation Case [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseTypeDomain" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_LitigationCaseTypeDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_LitigationCaseTypeDomain" xlink:to="lab_srt_LitigationCaseTypeDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativesFairValueLineItems_82d384ab-c659-4ece-a7fe-d3ba4936e2bc_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativesFairValueLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivatives Fair Value [Line Items]</link:label>
    <link:label id="lab_us-gaap_DerivativesFairValueLineItems_label_en-US" xlink:label="lab_us-gaap_DerivativesFairValueLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivatives, Fair Value [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativesFairValueLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativesFairValueLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativesFairValueLineItems" xlink:to="lab_us-gaap_DerivativesFairValueLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_USTreasuryBillSecuritiesMember_d7da49cf-a409-4b4a-bf8a-bbb12e56c500_terseLabel_en-US" xlink:label="lab_us-gaap_USTreasuryBillSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">U.S. Treasury bills [Member]</link:label>
    <link:label id="lab_us-gaap_USTreasuryBillSecuritiesMember_label_en-US" xlink:label="lab_us-gaap_USTreasuryBillSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">US Treasury Bill Securities [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasuryBillSecuritiesMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USTreasuryBillSecuritiesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_USTreasuryBillSecuritiesMember" xlink:to="lab_us-gaap_USTreasuryBillSecuritiesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StatementOfStockholdersEquityAbstract_2bade634-3963-49e5-b3f3-6795cbfa23b0_terseLabel_en-US" xlink:label="lab_us-gaap_StatementOfStockholdersEquityAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Stockholders' Equity [Abstract]</link:label>
    <link:label id="lab_us-gaap_StatementOfStockholdersEquityAbstract_label_en-US" xlink:label="lab_us-gaap_StatementOfStockholdersEquityAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Stockholders' Equity [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract" xlink:to="lab_us-gaap_StatementOfStockholdersEquityAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_b4d09be5-932c-424d-a1fe-b5fb0a8ae14e_terseLabel_en-US" xlink:label="lab_amgn_SixPointThreeSevenFivePercentNotesDue2037Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">6.375% notes due 2037 (6.375% 2037 Notes) [Member]</link:label>
    <link:label id="lab_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_label_en-US" xlink:label="lab_amgn_SixPointThreeSevenFivePercentNotesDue2037Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Six Point Three Seven Five Percent Notes Due 2037 [Member]</link:label>
    <link:label id="lab_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_documentation_en-US" xlink:label="lab_amgn_SixPointThreeSevenFivePercentNotesDue2037Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Six Point Three Seven Five Percent Notes Due 2037 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_SixPointThreeSevenFivePercentNotesDue2037Member" xlink:href="amgn-20210930.xsd#amgn_SixPointThreeSevenFivePercentNotesDue2037Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_SixPointThreeSevenFivePercentNotesDue2037Member" xlink:to="lab_amgn_SixPointThreeSevenFivePercentNotesDue2037Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_BusinessAcquisitionLineItems_6950bcb5-3f48-4fcf-a25a-5e3a6c5586aa_terseLabel_en-US" xlink:label="lab_us-gaap_BusinessAcquisitionLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Acquisition [Line Items]</link:label>
    <link:label id="lab_us-gaap_BusinessAcquisitionLineItems_label_en-US" xlink:label="lab_us-gaap_BusinessAcquisitionLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Acquisition [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems" xlink:to="lab_us-gaap_BusinessAcquisitionLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EquityMethodInvestments_ae801d1c-b41a-40aa-9cbe-2ec30699c489_terseLabel_en-US" xlink:label="lab_us-gaap_EquityMethodInvestments" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Carrying value of equity method investment</link:label>
    <link:label id="lab_us-gaap_EquityMethodInvestments_label_en-US" xlink:label="lab_us-gaap_EquityMethodInvestments" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investments</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestments" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestments"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EquityMethodInvestments" xlink:to="lab_us-gaap_EquityMethodInvestments" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_USTreasurySecuritiesMember_679bcc23-c49b-4031-9090-0954f92f9576_terseLabel_en-US" xlink:label="lab_us-gaap_USTreasurySecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">U.S. Treasury notes [Member]</link:label>
    <link:label id="lab_us-gaap_USTreasurySecuritiesMember_label_en-US" xlink:label="lab_us-gaap_USTreasurySecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">US Treasury Securities [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasurySecuritiesMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USTreasurySecuritiesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_USTreasurySecuritiesMember" xlink:to="lab_us-gaap_USTreasurySecuritiesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncomeStatementAbstract_5412da65-9828-469e-be52-fb27fcefcf01_terseLabel_en-US" xlink:label="lab_us-gaap_IncomeStatementAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income Statement [Abstract]</link:label>
    <link:label id="lab_us-gaap_IncomeStatementAbstract_label_en-US" xlink:label="lab_us-gaap_IncomeStatementAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income Statement [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncomeStatementAbstract" xlink:to="lab_us-gaap_IncomeStatementAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_AmendmentFlag_a6cc74eb-d30b-4b43-b9e0-de1d9db02563_terseLabel_en-US" xlink:label="lab_dei_AmendmentFlag" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amendment Flag</link:label>
    <link:label id="lab_dei_AmendmentFlag_label_en-US" xlink:label="lab_dei_AmendmentFlag" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amendment Flag</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_AmendmentFlag"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_AmendmentFlag" xlink:to="lab_dei_AmendmentFlag" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InventoryDisclosureAbstract_8ff4c660-b072-444a-a0f6-b1524059cd3b_terseLabel_en-US" xlink:label="lab_us-gaap_InventoryDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Inventory Disclosure [Abstract]</link:label>
    <link:label id="lab_us-gaap_InventoryDisclosureAbstract_label_en-US" xlink:label="lab_us-gaap_InventoryDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Inventory Disclosure [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryDisclosureAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InventoryDisclosureAbstract" xlink:to="lab_us-gaap_InventoryDisclosureAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_CorporateDebtSecuritiesFinancialMember_921a613f-c7e2-49f1-893e-282267cad38d_terseLabel_en-US" xlink:label="lab_amgn_CorporateDebtSecuritiesFinancialMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Corporate debt securities - Financial [Member]</link:label>
    <link:label id="lab_amgn_CorporateDebtSecuritiesFinancialMember_label_en-US" xlink:label="lab_amgn_CorporateDebtSecuritiesFinancialMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Corporate Debt Securities Financial [Member]</link:label>
    <link:label id="lab_amgn_CorporateDebtSecuritiesFinancialMember_documentation_en-US" xlink:label="lab_amgn_CorporateDebtSecuritiesFinancialMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Corporate debt securities financial Member.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesFinancialMember" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesFinancialMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_CorporateDebtSecuritiesFinancialMember" xlink:to="lab_amgn_CorporateDebtSecuritiesFinancialMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_dba1b1d3-84e6-4d15-903c-7fba655c9d80_terseLabel_en-US" xlink:label="lab_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.125% notes due 2020 (2.125% 2020 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_label_en-US" xlink:label="lab_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point One Two Five Percent Notes Due Two Zero Two Zero [Member]</link:label>
    <link:label id="lab_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_documentation_en-US" xlink:label="lab_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point One Two Five Percent Notes Due Two Zero Two Zero [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember" xlink:href="amgn-20210930.xsd#amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember" xlink:to="lab_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NotesPayableFairValueDisclosure_622b6b40-9c6a-43a7-8f6d-8f10d20e0ae7_terseLabel_en-US" xlink:label="lab_us-gaap_NotesPayableFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term debt, fair value</link:label>
    <link:label id="lab_us-gaap_NotesPayableFairValueDisclosure_label_en-US" xlink:label="lab_us-gaap_NotesPayableFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Notes Payable, Fair Value Disclosure</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesPayableFairValueDisclosure" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NotesPayableFairValueDisclosure"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NotesPayableFairValueDisclosure" xlink:to="lab_us-gaap_NotesPayableFairValueDisclosure" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_6d61c20f-ef72-4101-9db5-8300966c1eb5_terseLabel_en-US" xlink:label="lab_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Indefinite-lived intangible assets</link:label>
    <link:label id="lab_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_label_en-US" xlink:label="lab_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Indefinite-lived Intangible Assets (Excluding Goodwill)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill" xlink:to="lab_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_f7d40f47-c976-42b2-ae00-61ca6b6838fd_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Assets by Major Class [Axis]</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Assets by Major Class [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncomeTaxExpenseBenefit_989e709d-1367-4eff-b232-bd571df08eda_verboseLabel_en-US" xlink:label="lab_us-gaap_IncomeTaxExpenseBenefit" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Provision for income taxes</link:label>
    <link:label id="lab_us-gaap_IncomeTaxExpenseBenefit_8e6756dc-399a-41e9-ada5-a978be47b9cd_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_IncomeTaxExpenseBenefit" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Provision for income taxes</link:label>
    <link:label id="lab_us-gaap_IncomeTaxExpenseBenefit_label_en-US" xlink:label="lab_us-gaap_IncomeTaxExpenseBenefit" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income Tax Expense (Benefit)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit" xlink:to="lab_us-gaap_IncomeTaxExpenseBenefit" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_BasisOfPresentationPolicyTextBlock_41577744-93f3-4d81-9dfa-ebb1b7e21cb6_verboseLabel_en-US" xlink:label="lab_amgn_BasisOfPresentationPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Basis of presentation</link:label>
    <link:label id="lab_amgn_BasisOfPresentationPolicyTextBlock_label_en-US" xlink:label="lab_amgn_BasisOfPresentationPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Basis Of Presentation [Policy Text Block]</link:label>
    <link:label id="lab_amgn_BasisOfPresentationPolicyTextBlock_documentation_en-US" xlink:label="lab_amgn_BasisOfPresentationPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Shows the basis of presentation of financial information for interim periods.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_BasisOfPresentationPolicyTextBlock" xlink:href="amgn-20210930.xsd#amgn_BasisOfPresentationPolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_BasisOfPresentationPolicyTextBlock" xlink:to="lab_amgn_BasisOfPresentationPolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccountsReceivableNetCurrent_c8cee7fb-973a-45cd-b74b-5c75a0d7fdac_verboseLabel_en-US" xlink:label="lab_us-gaap_AccountsReceivableNetCurrent" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Trade receivables, net</link:label>
    <link:label id="lab_us-gaap_AccountsReceivableNetCurrent_label_en-US" xlink:label="lab_us-gaap_AccountsReceivableNetCurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accounts Receivable, after Allowance for Credit Loss, Current</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccountsReceivableNetCurrent" xlink:to="lab_us-gaap_AccountsReceivableNetCurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ProceedsFromIssuanceOfLongTermDebt_84249fbd-f1cf-4385-9f33-19b8dab5a62c_terseLabel_en-US" xlink:label="lab_us-gaap_ProceedsFromIssuanceOfLongTermDebt" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net proceeds from issuance of debt</link:label>
    <link:label id="lab_us-gaap_ProceedsFromIssuanceOfLongTermDebt_label_en-US" xlink:label="lab_us-gaap_ProceedsFromIssuanceOfLongTermDebt" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proceeds from Issuance of Long-term Debt</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromIssuanceOfLongTermDebt"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt" xlink:to="lab_us-gaap_ProceedsFromIssuanceOfLongTermDebt" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StatementEquityComponentsAxis_850060c6-3d1a-41f3-a18c-df38d7791497_terseLabel_en-US" xlink:label="lab_us-gaap_StatementEquityComponentsAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Components [Axis]</link:label>
    <link:label id="lab_us-gaap_StatementEquityComponentsAxis_label_en-US" xlink:label="lab_us-gaap_StatementEquityComponentsAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Components [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StatementEquityComponentsAxis" xlink:to="lab_us-gaap_StatementEquityComponentsAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_d4b4f6be-79c7-4e80-a26c-d0a3fb76aabe_terseLabel_en-US" xlink:label="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated Other Comprehensive Income (Loss) [Table]</link:label>
    <link:label id="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_label_en-US" xlink:label="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated Other Comprehensive Income (Loss) [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable" xlink:to="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_5aeb7408-0cc3-4b2a-a672-d2f33da961b1_terseLabel_en-US" xlink:label="lab_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">4.663% notes due 2051 (4.663% 2051 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_label_en-US" xlink:label="lab_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Four Point Six Six Three Percent Notes Due Two Zero Five One [Member]</link:label>
    <link:label id="lab_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_documentation_en-US" xlink:label="lab_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Four Point Six Six Three Percent Notes Due Two Zero Five One [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember" xlink:href="amgn-20210930.xsd#amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember" xlink:to="lab_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueDisclosuresAbstract_0d3c786a-fe3a-450e-ae95-8f5cb46cc9ac_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueDisclosuresAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Disclosures [Abstract]</link:label>
    <link:label id="lab_us-gaap_FairValueDisclosuresAbstract_label_en-US" xlink:label="lab_us-gaap_FairValueDisclosuresAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Disclosures [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract" xlink:to="lab_us-gaap_FairValueDisclosuresAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InvestmentTypeAxis_60001e67-2ee7-41ca-a178-eb04bd0a3198_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentTypeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investment Type [Axis]</link:label>
    <link:label id="lab_us-gaap_InvestmentTypeAxis_label_en-US" xlink:label="lab_us-gaap_InvestmentTypeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investment Type [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentTypeAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InvestmentTypeAxis" xlink:to="lab_us-gaap_InvestmentTypeAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_OtherProductsMember_1183a094-3a13-48f3-a5ce-44ade7ba84f2_terseLabel_en-US" xlink:label="lab_amgn_OtherProductsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other products [Member]</link:label>
    <link:label id="lab_amgn_OtherProductsMember_label_en-US" xlink:label="lab_amgn_OtherProductsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Products [Member]</link:label>
    <link:label id="lab_amgn_OtherProductsMember_documentation_en-US" xlink:label="lab_amgn_OtherProductsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Products [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherProductsMember" xlink:href="amgn-20210930.xsd#amgn_OtherProductsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OtherProductsMember" xlink:to="lab_amgn_OtherProductsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AssetsCurrent_d2817ebd-b421-4106-b5b2-c8fe6c44d509_totalLabel_en-US" xlink:label="lab_us-gaap_AssetsCurrent" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total current assets</link:label>
    <link:label id="lab_us-gaap_AssetsCurrent_label_en-US" xlink:label="lab_us-gaap_AssetsCurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets, Current</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsCurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AssetsCurrent" xlink:to="lab_us-gaap_AssetsCurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1_4114a414-35ef-43cb-b9b0-a144d7b7b3b3_terseLabel_en-US" xlink:label="lab_us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Gains (losses) on fair value hedging relationships, Derivatives designated as hedging instruments</link:label>
    <link:label id="lab_us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1_label_en-US" xlink:label="lab_us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Change in Unrealized Gain (Loss) on Fair Value Hedging Instruments</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1" xlink:to="lab_us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember_f33981e1-fa52-4fd4-a350-93b8be0dc73d_verboseLabel_en-US" xlink:label="lab_amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">1.25% 2022 euro Notes [Member]</link:label>
    <link:label id="lab_amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember_label_en-US" xlink:label="lab_amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">One Point Twenty Five Percent Euro Notes Due Two Thousand Twenty Two [Member]</link:label>
    <link:label id="lab_amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember_documentation_en-US" xlink:label="lab_amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">One Point Twenty Five Percent Euro Notes Due Two Thousand Twenty Two [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember" xlink:href="amgn-20210930.xsd#amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember" xlink:to="lab_amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_A1.250SeniorNotesDue2022Member_0f6f6758-cdf0-42fe-aedf-693529449c6c_terseLabel_en-US" xlink:label="lab_amgn_A1.250SeniorNotesDue2022Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">1.250% Senior Notes Due 2022 [Member]</link:label>
    <link:label id="lab_amgn_A1.250SeniorNotesDue2022Member_label_en-US" xlink:label="lab_amgn_A1.250SeniorNotesDue2022Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">1.250% Senior Notes Due 2022 [Member]</link:label>
    <link:label id="lab_amgn_A1.250SeniorNotesDue2022Member_documentation_en-US" xlink:label="lab_amgn_A1.250SeniorNotesDue2022Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">1.250% Senior Notes Due 2022 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_A1.250SeniorNotesDue2022Member" xlink:href="amgn-20210930.xsd#amgn_A1.250SeniorNotesDue2022Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_A1.250SeniorNotesDue2022Member" xlink:to="lab_amgn_A1.250SeniorNotesDue2022Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InventoryNet_3febfe82-1cf8-4bc2-9da0-25282d51217f_verboseLabel_en-US" xlink:label="lab_us-gaap_InventoryNet" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Inventories</link:label>
    <link:label id="lab_us-gaap_InventoryNet_07392a64-c2f1-45d8-a06d-aff0f5be6817_totalLabel_en-US" xlink:label="lab_us-gaap_InventoryNet" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total inventories</link:label>
    <link:label id="lab_us-gaap_InventoryNet_label_en-US" xlink:label="lab_us-gaap_InventoryNet" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Inventory, Net</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryNet"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InventoryNet" xlink:to="lab_us-gaap_InventoryNet" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfStockByClassTable_b01acd00-1ea8-46bb-b9c3-c0257c7e5868_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfStockByClassTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Stock by Class [Table]</link:label>
    <link:label id="lab_us-gaap_ScheduleOfStockByClassTable_label_en-US" xlink:label="lab_us-gaap_ScheduleOfStockByClassTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Stock by Class [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable" xlink:to="lab_us-gaap_ScheduleOfStockByClassTable" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ProliaMember_47377af9-3739-4388-bf92-63ec762b8b3d_terseLabel_en-US" xlink:label="lab_amgn_ProliaMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Prolia&#174; (denosumab) [Member]</link:label>
    <link:label id="lab_amgn_ProliaMember_label_en-US" xlink:label="lab_amgn_ProliaMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Prolia [Member]</link:label>
    <link:label id="lab_amgn_ProliaMember_documentation_en-US" xlink:label="lab_amgn_ProliaMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Prolia.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ProliaMember" xlink:href="amgn-20210930.xsd#amgn_ProliaMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ProliaMember" xlink:to="lab_amgn_ProliaMember" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityFileNumber_f2aca184-71b0-4cc6-a4db-60088630cea9_terseLabel_en-US" xlink:label="lab_dei_EntityFileNumber" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity File Number</link:label>
    <link:label id="lab_dei_EntityFileNumber_label_en-US" xlink:label="lab_dei_EntityFileNumber" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity File Number</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityFileNumber"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityFileNumber" xlink:to="lab_dei_EntityFileNumber" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockRepurchasedDuringPeriodValue_dad4a379-fbf6-4c05-a506-5c126172a35f_terseLabel_en-US" xlink:label="lab_us-gaap_StockRepurchasedDuringPeriodValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock repurchased</link:label>
    <link:label id="lab_us-gaap_StockRepurchasedDuringPeriodValue_label_en-US" xlink:label="lab_us-gaap_StockRepurchasedDuringPeriodValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock Repurchased During Period, Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchasedDuringPeriodValue" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchasedDuringPeriodValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockRepurchasedDuringPeriodValue" xlink:to="lab_us-gaap_StockRepurchasedDuringPeriodValue" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_1ac91345-4fc4-4a94-ad43-be60d39cc3ea_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]</link:label>
    <link:label id="lab_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_label_en-US" xlink:label="lab_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:to="lab_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StatementOfFinancialPositionAbstract_feed6736-8e45-4eb7-a03a-2d69700926d3_terseLabel_en-US" xlink:label="lab_us-gaap_StatementOfFinancialPositionAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Financial Position [Abstract]</link:label>
    <link:label id="lab_us-gaap_StatementOfFinancialPositionAbstract_label_en-US" xlink:label="lab_us-gaap_StatementOfFinancialPositionAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Financial Position [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract" xlink:to="lab_us-gaap_StatementOfFinancialPositionAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EquityMethodInvestmentAggregateCost_36300c34-303c-414d-9664-737f5b6126ef_terseLabel_en-US" xlink:label="lab_us-gaap_EquityMethodInvestmentAggregateCost" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investment, Aggregate Cost</link:label>
    <link:label id="lab_us-gaap_EquityMethodInvestmentAggregateCost_label_en-US" xlink:label="lab_us-gaap_EquityMethodInvestmentAggregateCost" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investment, Aggregate Cost</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentAggregateCost" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentAggregateCost"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EquityMethodInvestmentAggregateCost" xlink:to="lab_us-gaap_EquityMethodInvestmentAggregateCost" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_DerivativeInstrumentNameDomain_1f32f5cd-5bf0-4fab-b68a-5e12934fa45c_terseLabel_en-US" xlink:label="lab_amgn_DerivativeInstrumentNameDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instrument, Name [Domain]</link:label>
    <link:label id="lab_amgn_DerivativeInstrumentNameDomain_label_en-US" xlink:label="lab_amgn_DerivativeInstrumentNameDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instrument, Name [Domain]</link:label>
    <link:label id="lab_amgn_DerivativeInstrumentNameDomain_documentation_en-US" xlink:label="lab_amgn_DerivativeInstrumentNameDomain" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instrument, Name [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DerivativeInstrumentNameDomain" xlink:href="amgn-20210930.xsd#amgn_DerivativeInstrumentNameDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_DerivativeInstrumentNameDomain" xlink:to="lab_amgn_DerivativeInstrumentNameDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LongTermDebtCurrent_2fd95c74-7c21-496b-acb0-142c88b9c65b_terseLabel_en-US" xlink:label="lab_us-gaap_LongTermDebtCurrent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current portion of long-term debt</link:label>
    <link:label id="lab_us-gaap_LongTermDebtCurrent_deb6dd21-d14a-4b1d-aa88-70de7274410d_negatedLabel_en-US" xlink:label="lab_us-gaap_LongTermDebtCurrent" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Less current portion</link:label>
    <link:label id="lab_us-gaap_LongTermDebtCurrent_label_en-US" xlink:label="lab_us-gaap_LongTermDebtCurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term Debt, Current Maturities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LongTermDebtCurrent" xlink:to="lab_us-gaap_LongTermDebtCurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_ProductOrServiceAxis_2be29c6a-c3bb-4da1-a036-479d8fd44e8a_terseLabel_en-US" xlink:label="lab_srt_ProductOrServiceAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Product and Service [Axis]</link:label>
    <link:label id="lab_srt_ProductOrServiceAxis_label_en-US" xlink:label="lab_srt_ProductOrServiceAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Product and Service [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductOrServiceAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_ProductOrServiceAxis" xlink:to="lab_srt_ProductOrServiceAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityIncorporationStateCountryCode_bf3399b4-78a6-4eae-967c-6537a56e6963_terseLabel_en-US" xlink:label="lab_dei_EntityIncorporationStateCountryCode" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Incorporation, State or Country Code</link:label>
    <link:label id="lab_dei_EntityIncorporationStateCountryCode_label_en-US" xlink:label="lab_dei_EntityIncorporationStateCountryCode" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Incorporation, State or Country Code</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityIncorporationStateCountryCode" xlink:to="lab_dei_EntityIncorporationStateCountryCode" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeInstrumentsGainLossLineItems_6deaea9f-bac9-47ce-b542-9e7bce9909a7_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instruments, Gain (Loss) [Line Items]</link:label>
    <link:label id="lab_us-gaap_DerivativeInstrumentsGainLossLineItems_label_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instruments, Gain (Loss) [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:to="lab_us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntitySmallBusiness_2cd14d3b-1ebb-4df9-ab25-9cc5d6fdb440_terseLabel_en-US" xlink:label="lab_dei_EntitySmallBusiness" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Small Business</link:label>
    <link:label id="lab_dei_EntitySmallBusiness_label_en-US" xlink:label="lab_dei_EntitySmallBusiness" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Small Business</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntitySmallBusiness" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntitySmallBusiness"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntitySmallBusiness" xlink:to="lab_dei_EntitySmallBusiness" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FivePointThreeSevenFivePercentNotesDue2043Member_99998404-ee07-4dc1-b213-44b0435d06a0_terseLabel_en-US" xlink:label="lab_amgn_FivePointThreeSevenFivePercentNotesDue2043Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">5.375% notes due 2043 (5.375% 2043 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FivePointThreeSevenFivePercentNotesDue2043Member_label_en-US" xlink:label="lab_amgn_FivePointThreeSevenFivePercentNotesDue2043Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Five Point Three Seven Five Percent Notes Due 2043 [Member]</link:label>
    <link:label id="lab_amgn_FivePointThreeSevenFivePercentNotesDue2043Member_documentation_en-US" xlink:label="lab_amgn_FivePointThreeSevenFivePercentNotesDue2043Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Five Point Three Seven Five Percent Notes Due 2043 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointThreeSevenFivePercentNotesDue2043Member" xlink:href="amgn-20210930.xsd#amgn_FivePointThreeSevenFivePercentNotesDue2043Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FivePointThreeSevenFivePercentNotesDue2043Member" xlink:to="lab_amgn_FivePointThreeSevenFivePercentNotesDue2043Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount_b4928d29-294a-43ca-9bb9-d850af5ca55f_terseLabel_en-US" xlink:label="lab_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity securities without readily determinable fair value</link:label>
    <link:label id="lab_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount_label_en-US" xlink:label="lab_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Securities without Readily Determinable Fair Value, Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount" xlink:to="lab_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FourPercentPoundSterlingNotesDue2029Member_3e9a42cb-01ed-4bbe-ac0c-2e147254cfb3_terseLabel_en-US" xlink:label="lab_amgn_FourPercentPoundSterlingNotesDue2029Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">4.00% &#163;700 million notes due 2029 (4.00% 2029 pound sterling Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPercentPoundSterlingNotesDue2029Member_3496d7c4-2659-4986-b73a-54044f824d02_verboseLabel_en-US" xlink:label="lab_amgn_FourPercentPoundSterlingNotesDue2029Member" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">4.00% 2029 pound sterling Notes [Member]</link:label>
    <link:label id="lab_amgn_FourPercentPoundSterlingNotesDue2029Member_label_en-US" xlink:label="lab_amgn_FourPercentPoundSterlingNotesDue2029Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Four Percent Pound Sterling Notes Due 2029 [Member]</link:label>
    <link:label id="lab_amgn_FourPercentPoundSterlingNotesDue2029Member_documentation_en-US" xlink:label="lab_amgn_FourPercentPoundSterlingNotesDue2029Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Four Percent Pound Sterling Notes Due 2029 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPercentPoundSterlingNotesDue2029Member" xlink:href="amgn-20210930.xsd#amgn_FourPercentPoundSterlingNotesDue2029Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPercentPoundSterlingNotesDue2029Member" xlink:to="lab_amgn_FourPercentPoundSterlingNotesDue2029Member" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_6c1990cc-4488-4329-ab37-65d436baa8cb_terseLabel_en-US" xlink:label="lab_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">3.125% notes due 2025 (3.125% 2025 Notes) [Member]</link:label>
    <link:label id="lab_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_label_en-US" xlink:label="lab_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point One Two Five Percent Notes Due Two Zero Two Five [Member]</link:label>
    <link:label id="lab_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_documentation_en-US" xlink:label="lab_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point One Two Five Percent Notes Due Two Zero Two Five [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember" xlink:href="amgn-20210930.xsd#amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember" xlink:to="lab_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EquityComponentDomain_e8581d1c-84e5-4afc-af4b-1b7930ab927c_terseLabel_en-US" xlink:label="lab_us-gaap_EquityComponentDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Component [Domain]</link:label>
    <link:label id="lab_us-gaap_EquityComponentDomain_label_en-US" xlink:label="lab_us-gaap_EquityComponentDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Component [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EquityComponentDomain" xlink:to="lab_us-gaap_EquityComponentDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_5dbe9fa4-de45-4392-bf22-6ce4af365864_verboseLabel_en-US" xlink:label="lab_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Issuance of common stock in connection with the Company&#8217;s equity award programs, Shares</link:label>
    <link:label id="lab_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_label_en-US" xlink:label="lab_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Shares Issued, Shares, Share-based Payment Arrangement, after Forfeiture</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation" xlink:to="lab_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockholdersEquityOther_7aca4035-3906-4ad6-8471-59dd78748771_terseLabel_en-US" xlink:label="lab_us-gaap_StockholdersEquityOther" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other</link:label>
    <link:label id="lab_us-gaap_StockholdersEquityOther_label_en-US" xlink:label="lab_us-gaap_StockholdersEquityOther" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stockholders' Equity, Other</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityOther" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquityOther"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockholdersEquityOther" xlink:to="lab_us-gaap_StockholdersEquityOther" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockRepurchasedDuringPeriodShares_3d529fa4-528c-4808-aae6-ce4bdbb1b208_terseLabel_en-US" xlink:label="lab_us-gaap_StockRepurchasedDuringPeriodShares" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock repurchased, Shares</link:label>
    <link:label id="lab_us-gaap_StockRepurchasedDuringPeriodShares_label_en-US" xlink:label="lab_us-gaap_StockRepurchasedDuringPeriodShares" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stock Repurchased During Period, Shares</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchasedDuringPeriodShares" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchasedDuringPeriodShares"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockRepurchasedDuringPeriodShares" xlink:to="lab_us-gaap_StockRepurchasedDuringPeriodShares" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NotesPayableToBanksMember_c92556cc-2ef9-4dbb-bda1-23df555e1097_terseLabel_en-US" xlink:label="lab_us-gaap_NotesPayableToBanksMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Notes [Member]</link:label>
    <link:label id="lab_us-gaap_NotesPayableToBanksMember_label_en-US" xlink:label="lab_us-gaap_NotesPayableToBanksMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Notes Payable to Banks [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesPayableToBanksMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NotesPayableToBanksMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NotesPayableToBanksMember" xlink:to="lab_us-gaap_NotesPayableToBanksMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_6f3debc1-2ca1-4807-b7fa-67a3518d9733_terseLabel_en-US" xlink:label="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">0.41% CHF700 million bonds due 2023 (0.41% 2023 Swiss franc Bonds) [Member]</link:label>
    <link:label id="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_cbe8d829-f396-4227-9ab6-5a744a1c2ef8_verboseLabel_en-US" xlink:label="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">0.41% 2023 Swiss franc Bonds [Member]</link:label>
    <link:label id="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_label_en-US" xlink:label="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Zero Point Forty One Percent Swiss Franc Bonds Due Two Thousand Twenty Three [Member]</link:label>
    <link:label id="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_documentation_en-US" xlink:label="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Zero Point Forty One Percent Swiss Franc Bonds Due Two Thousand Twenty Three [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember" xlink:href="amgn-20210930.xsd#amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember" xlink:to="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_UpFrontPayment_fa9aee62-9ba0-4b5c-8eb0-54f2756735b0_terseLabel_en-US" xlink:label="lab_amgn_UpFrontPayment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Up-front payment</link:label>
    <link:label id="lab_amgn_UpFrontPayment_label_en-US" xlink:label="lab_amgn_UpFrontPayment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Up-front payment</link:label>
    <link:label id="lab_amgn_UpFrontPayment_documentation_en-US" xlink:label="lab_amgn_UpFrontPayment" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Up-front payment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_UpFrontPayment" xlink:href="amgn-20210930.xsd#amgn_UpFrontPayment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_UpFrontPayment" xlink:to="lab_amgn_UpFrontPayment" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_ExchangeDomain_e830ae1d-f9b2-4e13-ba87-315cc41aa783_terseLabel_en-US" xlink:label="lab_dei_ExchangeDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Exchange [Domain]</link:label>
    <link:label id="lab_dei_ExchangeDomain_label_en-US" xlink:label="lab_dei_ExchangeDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Exchange [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_ExchangeDomain" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_ExchangeDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_ExchangeDomain" xlink:to="lab_dei_ExchangeDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StatementLineItems_aefac1ee-dc55-4fa4-8400-cfa798a53913_terseLabel_en-US" xlink:label="lab_us-gaap_StatementLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement [Line Items]</link:label>
    <link:label id="lab_us-gaap_StatementLineItems_label_en-US" xlink:label="lab_us-gaap_StatementLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StatementLineItems" xlink:to="lab_us-gaap_StatementLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_LitigationCaseAxis_0a563023-560f-49d0-b058-b14bf4dc2fcc_terseLabel_en-US" xlink:label="lab_srt_LitigationCaseAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Litigation Case [Axis]</link:label>
    <link:label id="lab_srt_LitigationCaseAxis_label_en-US" xlink:label="lab_srt_LitigationCaseAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Litigation Case [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseAxis" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_LitigationCaseAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_LitigationCaseAxis" xlink:to="lab_srt_LitigationCaseAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FourPointFiveZeroPercentNotesDue2020Member_4cfcda94-8852-422b-b014-60577bca5afd_terseLabel_en-US" xlink:label="lab_amgn_FourPointFiveZeroPercentNotesDue2020Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">4.50% notes due 2020 (4.50% 2020 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPointFiveZeroPercentNotesDue2020Member_label_en-US" xlink:label="lab_amgn_FourPointFiveZeroPercentNotesDue2020Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Four Point Five Zero Percent Notes Due 2020 [Member]</link:label>
    <link:label id="lab_amgn_FourPointFiveZeroPercentNotesDue2020Member_documentation_en-US" xlink:label="lab_amgn_FourPointFiveZeroPercentNotesDue2020Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Four Point Five Zero Percent Notes Due 2020 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointFiveZeroPercentNotesDue2020Member" xlink:href="amgn-20210930.xsd#amgn_FourPointFiveZeroPercentNotesDue2020Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPointFiveZeroPercentNotesDue2020Member" xlink:to="lab_amgn_FourPointFiveZeroPercentNotesDue2020Member" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity_efad80f2-b45d-410c-aac4-e208f2a19309_terseLabel_en-US" xlink:label="lab_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investment, Amortization of Difference Between Carrying Amount and Underlying Equity</link:label>
    <link:label id="lab_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity_label_en-US" xlink:label="lab_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investment, Amortization of Difference Between Carrying Amount and Underlying Equity</link:label>
    <link:label id="lab_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity_documentation_en-US" xlink:label="lab_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investment, Amortization of Difference Between Carrying Amount and Underlying Equity</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity" xlink:href="amgn-20210930.xsd#amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity" xlink:to="lab_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock_c3108620-cea2-44b7-8013-737a6444c44f_verboseLabel_en-US" xlink:label="lab_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair values of available-for-sale investments by classification in the Consolidated Balance Sheets</link:label>
    <link:label id="lab_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock_label_en-US" xlink:label="lab_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Values of Available for Sale Investments By Classification In Consolidated Balance Sheets [Table Text Block]</link:label>
    <link:label id="lab_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock_documentation_en-US" xlink:label="lab_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Tabular disclosure of fair values of available-for-sale investments by classification in the consolidated balance sheets.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock" xlink:href="amgn-20210930.xsd#amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock" xlink:to="lab_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_TwoPointTwoZeroNotesDue2020Member_01727243-581a-4b49-a938-aeea99dc2cbb_terseLabel_en-US" xlink:label="lab_amgn_TwoPointTwoZeroNotesDue2020Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.20% notes due 2020 (2.20% 2020 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointTwoZeroNotesDue2020Member_label_en-US" xlink:label="lab_amgn_TwoPointTwoZeroNotesDue2020Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Two Zero Notes Due 2020 [Member]</link:label>
    <link:label id="lab_amgn_TwoPointTwoZeroNotesDue2020Member_documentation_en-US" xlink:label="lab_amgn_TwoPointTwoZeroNotesDue2020Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Two Zero Notes Due 2020 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointTwoZeroNotesDue2020Member" xlink:href="amgn-20210930.xsd#amgn_TwoPointTwoZeroNotesDue2020Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointTwoZeroNotesDue2020Member" xlink:to="lab_amgn_TwoPointTwoZeroNotesDue2020Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock_3205519a-bfb5-43e5-b9ac-5b5fdcbe7d99_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Summary of amounts of income and expense line items</link:label>
    <link:label id="lab_us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Derivatives Instruments Statements of Financial Performance and Financial Position, Location [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:to="lab_us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_433b86a0-12c4-41cc-a861-b00c0ac7fe06_terseLabel_en-US" xlink:label="lab_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Issuance of common stock in connection with the Company&#8217;s equity award programs</link:label>
    <link:label id="lab_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_label_en-US" xlink:label="lab_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Shares Issued, Value, Share-based Payment Arrangement, after Forfeiture</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation" xlink:to="lab_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesDebtSecurities_b3ce501f-0f76-4757-9d54-18daed5c25dc_terseLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesDebtSecurities" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair values</link:label>
    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesDebtSecurities_c5487c32-f4e1-4929-ab31-8f70e087e046_totalLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesDebtSecurities" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total interest-bearing securities</link:label>
    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesDebtSecurities_f44fe0de-8218-4669-91ad-0e257a951354_verboseLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesDebtSecurities" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest-bearing securities</link:label>
    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesDebtSecurities_label_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesDebtSecurities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities" xlink:to="lab_us-gaap_AvailableForSaleSecuritiesDebtSecurities" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_0d153f2a-b56f-432f-8923-dca029622433_terseLabel_en-US" xlink:label="lab_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, High</link:label>
    <link:label id="lab_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_label_en-US" xlink:label="lab_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, High</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh" xlink:to="lab_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_A300NotesDue20523002052NotesMember_1f2a42a0-efe4-4b1a-ac19-e3563ebb5447_terseLabel_en-US" xlink:label="lab_amgn_A300NotesDue20523002052NotesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">3.00% notes due 2052 (3.00% 2052 Notes)</link:label>
    <link:label id="lab_amgn_A300NotesDue20523002052NotesMember_label_en-US" xlink:label="lab_amgn_A300NotesDue20523002052NotesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">3.00% notes due 2052 (3.00% 2052 Notes) [Member]</link:label>
    <link:label id="lab_amgn_A300NotesDue20523002052NotesMember_documentation_en-US" xlink:label="lab_amgn_A300NotesDue20523002052NotesMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">3.00% notes due 2052 (3.00% 2052 Notes)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_A300NotesDue20523002052NotesMember" xlink:href="amgn-20210930.xsd#amgn_A300NotesDue20523002052NotesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_A300NotesDue20523002052NotesMember" xlink:to="lab_amgn_A300NotesDue20523002052NotesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtDisclosureAbstract_635190e8-e126-4985-9508-13eb640cd426_terseLabel_en-US" xlink:label="lab_us-gaap_DebtDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Disclosure [Abstract]</link:label>
    <link:label id="lab_us-gaap_DebtDisclosureAbstract_label_en-US" xlink:label="lab_us-gaap_DebtDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Disclosure [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtDisclosureAbstract" xlink:to="lab_us-gaap_DebtDisclosureAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeLiabilityFairValueNetAbstract_5d1ecf59-52bf-4614-85a7-8e3fb503078d_verboseLabel_en-US" xlink:label="lab_us-gaap_DerivativeLiabilityFairValueNetAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liabilities</link:label>
    <link:label id="lab_us-gaap_DerivativeLiabilityFairValueNetAbstract_label_en-US" xlink:label="lab_us-gaap_DerivativeLiabilityFairValueNetAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Liability, Fair Value, Amount Not Offset Against Collateral [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilityFairValueNetAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeLiabilityFairValueNetAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeLiabilityFairValueNetAbstract" xlink:to="lab_us-gaap_DerivativeLiabilityFairValueNetAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityAddressStateOrProvince_36461da0-93e3-49ac-8c17-9a45e48f3947_terseLabel_en-US" xlink:label="lab_dei_EntityAddressStateOrProvince" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Address, State or Province</link:label>
    <link:label id="lab_dei_EntityAddressStateOrProvince_label_en-US" xlink:label="lab_dei_EntityAddressStateOrProvince" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Address, State or Province</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressStateOrProvince"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityAddressStateOrProvince" xlink:to="lab_dei_EntityAddressStateOrProvince" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PaymentsToAcquireMarketableSecurities_76d9a24b-0c24-4af6-b9e0-3f637a54dbb9_negatedLabel_en-US" xlink:label="lab_us-gaap_PaymentsToAcquireMarketableSecurities" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Purchases of marketable securities</link:label>
    <link:label id="lab_us-gaap_PaymentsToAcquireMarketableSecurities_label_en-US" xlink:label="lab_us-gaap_PaymentsToAcquireMarketableSecurities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Payments to Acquire Marketable Securities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireMarketableSecurities" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireMarketableSecurities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PaymentsToAcquireMarketableSecurities" xlink:to="lab_us-gaap_PaymentsToAcquireMarketableSecurities" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueInputsLevel2Member_1f24bfe9-fb71-4a67-a266-b0d58639b35e_verboseLabel_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel2Member" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Significant other observable inputs (Level 2) [Member]</link:label>
    <link:label id="lab_us-gaap_FairValueInputsLevel2Member_label_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel2Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, Inputs, Level 2 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel2Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueInputsLevel2Member" xlink:to="lab_us-gaap_FairValueInputsLevel2Member" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_OtherCurrentNoncurrentAssetsMember_2f6e4608-8337-4af2-a289-44de60c65390_verboseLabel_en-US" xlink:label="lab_amgn_OtherCurrentNoncurrentAssetsMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other current assets/Other assets [Member]</link:label>
    <link:label id="lab_amgn_OtherCurrentNoncurrentAssetsMember_label_en-US" xlink:label="lab_amgn_OtherCurrentNoncurrentAssetsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Current Noncurrent Assets [Member]</link:label>
    <link:label id="lab_amgn_OtherCurrentNoncurrentAssetsMember_documentation_en-US" xlink:label="lab_amgn_OtherCurrentNoncurrentAssetsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other current assets/other non-current assets.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherCurrentNoncurrentAssetsMember" xlink:href="amgn-20210930.xsd#amgn_OtherCurrentNoncurrentAssetsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OtherCurrentNoncurrentAssetsMember" xlink:to="lab_amgn_OtherCurrentNoncurrentAssetsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_165fb9a3-5c0a-4eb9-a894-64d0314ca66f_totalLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Amortized cost</link:label>
    <link:label id="lab_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_label_en-US" xlink:label="lab_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale, Amortized Cost</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis" xlink:to="lab_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetUsefulLife_763075b5-9e82-49de-9d94-ea9ac7aba076_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Asset, Useful Life</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetUsefulLife_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Asset, Useful Life</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_e0ae7584-38e7-4d96-8406-17c3667f12b7_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Revenue from External Customers by Products and Services [Table]</link:label>
    <link:label id="lab_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_label_en-US" xlink:label="lab_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Revenue from External Customers by Products and Services [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable" xlink:to="lab_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_UseOfEstimates_06d4014d-dfd4-4be8-87ab-373165e0d41d_verboseLabel_en-US" xlink:label="lab_us-gaap_UseOfEstimates" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Use of estimates</link:label>
    <link:label id="lab_us-gaap_UseOfEstimates_label_en-US" xlink:label="lab_us-gaap_UseOfEstimates" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Use of Estimates, Policy [Policy Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UseOfEstimates" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_UseOfEstimates"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_UseOfEstimates" xlink:to="lab_us-gaap_UseOfEstimates" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_KyprolisANDAPatentLitigationMember_b4eb48ba-8282-4b92-ae3f-fb5c2a822eaf_terseLabel_en-US" xlink:label="lab_amgn_KyprolisANDAPatentLitigationMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Kyprolis ANDA Patent Litigation</link:label>
    <link:label id="lab_amgn_KyprolisANDAPatentLitigationMember_label_en-US" xlink:label="lab_amgn_KyprolisANDAPatentLitigationMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Kyprolis ANDA Patent Litigation [Member]</link:label>
    <link:label id="lab_amgn_KyprolisANDAPatentLitigationMember_documentation_en-US" xlink:label="lab_amgn_KyprolisANDAPatentLitigationMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Kyprolis ANDA Patent Litigation</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_KyprolisANDAPatentLitigationMember" xlink:href="amgn-20210930.xsd#amgn_KyprolisANDAPatentLitigationMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_KyprolisANDAPatentLitigationMember" xlink:to="lab_amgn_KyprolisANDAPatentLitigationMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_be47e6a6-d99e-409e-88cd-652cd6f50c2f_verboseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Computation for basic and diluted earnings per share</link:label>
    <link:label id="lab_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:to="lab_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityShellCompany_9f5fe1c2-0497-40f0-a7f5-16af3ebcfed5_terseLabel_en-US" xlink:label="lab_dei_EntityShellCompany" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Shell Company</link:label>
    <link:label id="lab_dei_EntityShellCompany_label_en-US" xlink:label="lab_dei_EntityShellCompany" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Shell Company</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityShellCompany" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityShellCompany"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityShellCompany" xlink:to="lab_dei_EntityShellCompany" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_39f6bf67-dc2b-4dc6-b428-2aa2df4d45e2_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Business Acquisitions, by Acquisition [Table]</link:label>
    <link:label id="lab_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_label_en-US" xlink:label="lab_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Business Acquisitions, by Acquisition [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:to="lab_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_LocalPhoneNumber_86a9bc77-3189-4722-abcb-10eb461f99f5_terseLabel_en-US" xlink:label="lab_dei_LocalPhoneNumber" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Local Phone Number</link:label>
    <link:label id="lab_dei_LocalPhoneNumber_label_en-US" xlink:label="lab_dei_LocalPhoneNumber" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Local Phone Number</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_LocalPhoneNumber"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_LocalPhoneNumber" xlink:to="lab_dei_LocalPhoneNumber" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_PatentTrialAndAppealBoardPatentChallengesMember_561154ce-2a51-44b5-9b09-ec641b4afe5b_terseLabel_en-US" xlink:label="lab_amgn_PatentTrialAndAppealBoardPatentChallengesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Patent Trial and Appeal Board Patent Challenges [Member]</link:label>
    <link:label id="lab_amgn_PatentTrialAndAppealBoardPatentChallengesMember_label_en-US" xlink:label="lab_amgn_PatentTrialAndAppealBoardPatentChallengesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Patent Trial And Appeal Board Patent Challenges [Member]</link:label>
    <link:label id="lab_amgn_PatentTrialAndAppealBoardPatentChallengesMember_documentation_en-US" xlink:label="lab_amgn_PatentTrialAndAppealBoardPatentChallengesMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Patent Trial And Appeal Board Patent Challenges [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_PatentTrialAndAppealBoardPatentChallengesMember" xlink:href="amgn-20210930.xsd#amgn_PatentTrialAndAppealBoardPatentChallengesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_PatentTrialAndAppealBoardPatentChallengesMember" xlink:to="lab_amgn_PatentTrialAndAppealBoardPatentChallengesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_37c4513d-cfeb-413a-9b62-6d5af922b6e8_totalLabel_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other comprehensive income (loss), net of taxes</link:label>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_label_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:to="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_ScenarioForecastMember_451eb94d-b56c-4d2c-a8be-9c1e4019ea1e_terseLabel_en-US" xlink:label="lab_srt_ScenarioForecastMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Forecast [Member]</link:label>
    <link:label id="lab_srt_ScenarioForecastMember_label_en-US" xlink:label="lab_srt_ScenarioForecastMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Forecast [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioForecastMember" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ScenarioForecastMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_ScenarioForecastMember" xlink:to="lab_srt_ScenarioForecastMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherLongTermDebt_47e55118-d69d-4413-a3ed-c5d71000dc4b_terseLabel_en-US" xlink:label="lab_us-gaap_OtherLongTermDebt" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other</link:label>
    <link:label id="lab_us-gaap_OtherLongTermDebt_label_en-US" xlink:label="lab_us-gaap_OtherLongTermDebt" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Long-term Debt</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLongTermDebt" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherLongTermDebt"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherLongTermDebt" xlink:to="lab_us-gaap_OtherLongTermDebt" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_e94d41f0-abed-4105-a58a-0cb83d828d8b_terseLabel_en-US" xlink:label="lab_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.25% notes due 2023 (2.25% 2023 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_label_en-US" xlink:label="lab_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Two Five Percent Notes Due Two Zero Two Three [Member]</link:label>
    <link:label id="lab_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_documentation_en-US" xlink:label="lab_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Two Five Percent Notes Due Two Zero Two Three [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember" xlink:href="amgn-20210930.xsd#amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember" xlink:to="lab_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_Assets_b84ed98b-91b3-4d1d-97c6-b019839b7c89_totalLabel_en-US" xlink:label="lab_us-gaap_Assets" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total assets</link:label>
    <link:label id="lab_us-gaap_Assets_label_en-US" xlink:label="lab_us-gaap_Assets" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Assets"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_Assets" xlink:to="lab_us-gaap_Assets" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_SensiparAntitrustClassActionsMember_a2fed1d6-aa62-488f-a000-594eeacb10b0_terseLabel_en-US" xlink:label="lab_amgn_SensiparAntitrustClassActionsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Sensipar Antitrust Class Actions [Member]</link:label>
    <link:label id="lab_amgn_SensiparAntitrustClassActionsMember_label_en-US" xlink:label="lab_amgn_SensiparAntitrustClassActionsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Sensipar Antitrust Class Actions [Member]</link:label>
    <link:label id="lab_amgn_SensiparAntitrustClassActionsMember_documentation_en-US" xlink:label="lab_amgn_SensiparAntitrustClassActionsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Sensipar Antitrust Class Actions [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_SensiparAntitrustClassActionsMember" xlink:href="amgn-20210930.xsd#amgn_SensiparAntitrustClassActionsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_SensiparAntitrustClassActionsMember" xlink:to="lab_amgn_SensiparAntitrustClassActionsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DeferredIncomeTaxesAndTaxCredits_ceb7214d-6644-46a6-b1d4-851cc6a2a9ad_terseLabel_en-US" xlink:label="lab_us-gaap_DeferredIncomeTaxesAndTaxCredits" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deferred income taxes</link:label>
    <link:label id="lab_us-gaap_DeferredIncomeTaxesAndTaxCredits_label_en-US" xlink:label="lab_us-gaap_DeferredIncomeTaxesAndTaxCredits" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Deferred Income Taxes and Tax Credits</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxesAndTaxCredits" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DeferredIncomeTaxesAndTaxCredits"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DeferredIncomeTaxesAndTaxCredits" xlink:to="lab_us-gaap_DeferredIncomeTaxesAndTaxCredits" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommonStockSharesAuthorized_2e5cd910-5f23-4d66-93ff-dd94e32d8854_verboseLabel_en-US" xlink:label="lab_us-gaap_CommonStockSharesAuthorized" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock and additional paid-in capital, shares authorized</link:label>
    <link:label id="lab_us-gaap_CommonStockSharesAuthorized_label_en-US" xlink:label="lab_us-gaap_CommonStockSharesAuthorized" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common Stock, Shares Authorized</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommonStockSharesAuthorized" xlink:to="lab_us-gaap_CommonStockSharesAuthorized" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_TwoPointSixFiveNotesDue2022Member_4a0d064a-a732-460b-8680-2146187165f6_terseLabel_en-US" xlink:label="lab_amgn_TwoPointSixFiveNotesDue2022Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.65% notes due 2022 (2.65% 2022 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointSixFiveNotesDue2022Member_label_en-US" xlink:label="lab_amgn_TwoPointSixFiveNotesDue2022Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Six Five Notes Due 2022 [Member]</link:label>
    <link:label id="lab_amgn_TwoPointSixFiveNotesDue2022Member_documentation_en-US" xlink:label="lab_amgn_TwoPointSixFiveNotesDue2022Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Six Five Notes Due 2022 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointSixFiveNotesDue2022Member" xlink:href="amgn-20210930.xsd#amgn_TwoPointSixFiveNotesDue2022Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointSixFiveNotesDue2022Member" xlink:to="lab_amgn_TwoPointSixFiveNotesDue2022Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NetIncomeLossAbstract_a75377f9-af32-4909-a007-3eb707c6c634_verboseLabel_en-US" xlink:label="lab_us-gaap_NetIncomeLossAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income (Numerator):</link:label>
    <link:label id="lab_us-gaap_NetIncomeLossAbstract_label_en-US" xlink:label="lab_us-gaap_NetIncomeLossAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Income (Loss) Attributable to Parent [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLossAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NetIncomeLossAbstract" xlink:to="lab_us-gaap_NetIncomeLossAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_SegmentGeographicalDomain_af398793-6933-4068-9b63-198edca7f5f6_terseLabel_en-US" xlink:label="lab_srt_SegmentGeographicalDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Geographical [Domain]</link:label>
    <link:label id="lab_srt_SegmentGeographicalDomain_label_en-US" xlink:label="lab_srt_SegmentGeographicalDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Geographical [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_SegmentGeographicalDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_SegmentGeographicalDomain" xlink:to="lab_srt_SegmentGeographicalDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_ProductsAndServicesDomain_66e0259b-664e-4833-b9b9-78268b42ec43_terseLabel_en-US" xlink:label="lab_srt_ProductsAndServicesDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Product and Service [Domain]</link:label>
    <link:label id="lab_srt_ProductsAndServicesDomain_label_en-US" xlink:label="lab_srt_ProductsAndServicesDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Product and Service [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_ProductsAndServicesDomain" xlink:to="lab_srt_ProductsAndServicesDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_AlternativeInvestmentNetGainLoss_8793c837-e4b2-46d3-8e04-097eaf077009_terseLabel_en-US" xlink:label="lab_amgn_AlternativeInvestmentNetGainLoss" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net gains (losses) from limited partnership investments</link:label>
    <link:label id="lab_amgn_AlternativeInvestmentNetGainLoss_label_en-US" xlink:label="lab_amgn_AlternativeInvestmentNetGainLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Alternative Investment, Net Gain (Loss)</link:label>
    <link:label id="lab_amgn_AlternativeInvestmentNetGainLoss_documentation_en-US" xlink:label="lab_amgn_AlternativeInvestmentNetGainLoss" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Alternative Investment, Net Gain (Loss)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AlternativeInvestmentNetGainLoss" xlink:href="amgn-20210930.xsd#amgn_AlternativeInvestmentNetGainLoss"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_AlternativeInvestmentNetGainLoss" xlink:to="lab_amgn_AlternativeInvestmentNetGainLoss" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtInstrumentInterestRateStatedPercentage_fdb292c7-7bf3-4740-b1a3-dde246462da0_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Interest rate, stated percentage</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentInterestRateStatedPercentage_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument, Interest Rate, Stated Percentage</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:to="lab_us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeContractTypeDomain_c0283dfc-91f9-4a88-9dfe-c301c98e1f84_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeContractTypeDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Contract [Domain]</link:label>
    <link:label id="lab_us-gaap_DerivativeContractTypeDomain_label_en-US" xlink:label="lab_us-gaap_DerivativeContractTypeDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Contract [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeContractTypeDomain" xlink:to="lab_us-gaap_DerivativeContractTypeDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_BusinessCombinationContingentConsiderationLiability_288f20fb-36c2-4ffd-a4d5-e5805ff3c9e2_verboseLabel_en-US" xlink:label="lab_us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Contingent consideration obligations</link:label>
    <link:label id="lab_us-gaap_BusinessCombinationContingentConsiderationLiability_label_en-US" xlink:label="lab_us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Combination, Contingent Consideration, Liability</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:to="lab_us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SignificantAccountingPoliciesTextBlock_ab1e73c8-1ed4-493d-b614-770b7c186e45_verboseLabel_en-US" xlink:label="lab_us-gaap_SignificantAccountingPoliciesTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Summary of significant accounting policies</link:label>
    <link:label id="lab_us-gaap_SignificantAccountingPoliciesTextBlock_label_en-US" xlink:label="lab_us-gaap_SignificantAccountingPoliciesTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Significant Accounting Policies [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SignificantAccountingPoliciesTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SignificantAccountingPoliciesTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SignificantAccountingPoliciesTextBlock" xlink:to="lab_us-gaap_SignificantAccountingPoliciesTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_CumulativeEffectPeriodOfAdoptionDomain_69204edc-aa39-4c84-9334-74eabb184a82_terseLabel_en-US" xlink:label="lab_srt_CumulativeEffectPeriodOfAdoptionDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cumulative Effect, Period of Adoption [Domain]</link:label>
    <link:label id="lab_srt_CumulativeEffectPeriodOfAdoptionDomain_label_en-US" xlink:label="lab_srt_CumulativeEffectPeriodOfAdoptionDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cumulative Effect, Period of Adoption [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionDomain" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionDomain" xlink:to="lab_srt_CumulativeEffectPeriodOfAdoptionDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_currency_AllCurrenciesDomain_7593c06b-3c67-4a1a-8f54-edd638c0e52e_terseLabel_en-US" xlink:label="lab_currency_AllCurrenciesDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">All Currencies [Domain]</link:label>
    <link:label id="lab_currency_AllCurrenciesDomain_label_en-US" xlink:label="lab_currency_AllCurrenciesDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">All Currencies [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_currency_AllCurrenciesDomain" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_AllCurrenciesDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_currency_AllCurrenciesDomain" xlink:to="lab_currency_AllCurrenciesDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInOperatingActivities_9418cc6a-9b15-49c4-a246-6245fde07d4a_totalLabel_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net cash provided by operating activities</link:label>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInOperatingActivities_label_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Cash Provided by (Used in) Operating Activities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:to="lab_us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_LossContingencyNumberOfLawsuits_ffbbcca1-1df2-4151-be11-2407599e369d_terseLabel_en-US" xlink:label="lab_amgn_LossContingencyNumberOfLawsuits" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Number of lawsuits</link:label>
    <link:label id="lab_amgn_LossContingencyNumberOfLawsuits_label_en-US" xlink:label="lab_amgn_LossContingencyNumberOfLawsuits" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, Number Of Lawsuits</link:label>
    <link:label id="lab_amgn_LossContingencyNumberOfLawsuits_documentation_en-US" xlink:label="lab_amgn_LossContingencyNumberOfLawsuits" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, Number Of Lawsuits</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LossContingencyNumberOfLawsuits" xlink:href="amgn-20210930.xsd#amgn_LossContingencyNumberOfLawsuits"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_LossContingencyNumberOfLawsuits" xlink:to="lab_amgn_LossContingencyNumberOfLawsuits" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_338dbcf8-9f7e-4eb0-9a7e-0450a5d34b89_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, Recurring and Nonrecurring [Table]</link:label>
    <link:label id="lab_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_label_en-US" xlink:label="lab_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value, Recurring and Nonrecurring [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:to="lab_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtInstrumentTable_29aa5db2-5a29-49a9-b5f2-042cdabb6d4a_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Long-term Debt Instruments [Table]</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentTable_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Long-term Debt Instruments [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentTable" xlink:to="lab_us-gaap_DebtInstrumentTable" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityTaxIdentificationNumber_1f31d338-f0c4-4598-b7c1-5be016af6f31_terseLabel_en-US" xlink:label="lab_dei_EntityTaxIdentificationNumber" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Tax Identification Number</link:label>
    <link:label id="lab_dei_EntityTaxIdentificationNumber_label_en-US" xlink:label="lab_dei_EntityTaxIdentificationNumber" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Tax Identification Number</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityTaxIdentificationNumber" xlink:to="lab_dei_EntityTaxIdentificationNumber" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SubsequentEventLineItems_42d449c6-880a-46c5-aaf9-05500483f02d_terseLabel_en-US" xlink:label="lab_us-gaap_SubsequentEventLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Subsequent Event [Line Items]</link:label>
    <link:label id="lab_us-gaap_SubsequentEventLineItems_label_en-US" xlink:label="lab_us-gaap_SubsequentEventLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Subsequent Event [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SubsequentEventLineItems" xlink:to="lab_us-gaap_SubsequentEventLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_StatementGeographicalAxis_624058d7-2454-4528-9b96-56467615ad75_terseLabel_en-US" xlink:label="lab_srt_StatementGeographicalAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Geographical [Axis]</link:label>
    <link:label id="lab_srt_StatementGeographicalAxis_label_en-US" xlink:label="lab_srt_StatementGeographicalAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Geographical [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementGeographicalAxis" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_StatementGeographicalAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_StatementGeographicalAxis" xlink:to="lab_srt_StatementGeographicalAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_abaf0518-986f-44c0-ad4a-65fb2b9380d8_terseLabel_en-US" xlink:label="lab_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Values Derivatives Balance Sheet Location By Derivative Contract Type By Hedging Designation [Table]</link:label>
    <link:label id="lab_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_label_en-US" xlink:label="lab_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Values Derivatives, Balance Sheet Location, by Derivative Contract Type [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable" xlink:to="lab_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent_7a25ab79-d8f4-466f-8dc4-d3ddfc1b8ecb_terseLabel_en-US" xlink:label="lab_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event</link:label>
    <link:label id="lab_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent_label_en-US" xlink:label="lab_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event</link:label>
    <link:label id="lab_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent_documentation_en-US" xlink:label="lab_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent" xlink:href="amgn-20210930.xsd#amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent" xlink:to="lab_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_015ccf1a-7df6-4692-abcb-2e3fe47168ea_terseLabel_en-US" xlink:label="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">4.563% notes due 2048 (4.563% 2048 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_66b20bf9-625a-48a0-ab22-42593828d467_verboseLabel_en-US" xlink:label="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">4.563% notes due 2048 (4.563% 2048 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_label_en-US" xlink:label="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Four Point Five Six Three Percent Notes Due Two Zero Four Eight [Member]</link:label>
    <link:label id="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_documentation_en-US" xlink:label="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Four Point Five Six Three Percent Notes Due Two Zero Four Eight [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember" xlink:href="amgn-20210930.xsd#amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember" xlink:to="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_14ecac6b-ead1-4624-b15b-b3c295f618de_verboseLabel_en-US" xlink:label="lab_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Basic (in shares)</link:label>
    <link:label id="lab_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_197373cf-337a-44b5-8dbb-c742091c859c_terseLabel_en-US" xlink:label="lab_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Weighted-average shares for basic EPS (in shares)</link:label>
    <link:label id="lab_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_label_en-US" xlink:label="lab_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Weighted Average Number of Shares Outstanding, Basic</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:to="lab_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EarningsPerShareDiluted_5c684d85-af03-4821-916a-3c1a72fd07cf_verboseLabel_en-US" xlink:label="lab_us-gaap_EarningsPerShareDiluted" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Diluted (in usd per share)</link:label>
    <link:label id="lab_us-gaap_EarningsPerShareDiluted_bde5836f-6b08-4451-b024-8218e4f9ab74_terseLabel_en-US" xlink:label="lab_us-gaap_EarningsPerShareDiluted" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Diluted EPS (in usd per share)</link:label>
    <link:label id="lab_us-gaap_EarningsPerShareDiluted_label_en-US" xlink:label="lab_us-gaap_EarningsPerShareDiluted" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Earnings Per Share, Diluted</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareDiluted"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EarningsPerShareDiluted" xlink:to="lab_us-gaap_EarningsPerShareDiluted" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_e38862d4-f297-4c00-8068-f6bbf8790f7a_verboseLabel_en-US" xlink:label="lab_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Effect of dilutive securities (in shares)</link:label>
    <link:label id="lab_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_label_en-US" xlink:label="lab_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Weighted Average Number Diluted Shares Outstanding Adjustment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment" xlink:to="lab_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ProductMember_9ef2fd8f-40c9-4337-8246-ffb7480857f5_terseLabel_en-US" xlink:label="lab_us-gaap_ProductMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Product sales [Member]</link:label>
    <link:label id="lab_us-gaap_ProductMember_label_en-US" xlink:label="lab_us-gaap_ProductMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Product [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ProductMember" xlink:to="lab_us-gaap_ProductMember" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityListingsExchangeAxis_17fc6cb9-ee25-4070-ace5-0e7889f4b9ea_terseLabel_en-US" xlink:label="lab_dei_EntityListingsExchangeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Listings, Exchange [Axis]</link:label>
    <link:label id="lab_dei_EntityListingsExchangeAxis_label_en-US" xlink:label="lab_dei_EntityListingsExchangeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Listings, Exchange [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityListingsExchangeAxis" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityListingsExchangeAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityListingsExchangeAxis" xlink:to="lab_dei_EntityListingsExchangeAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_3bd45439-30c3-4a7f-9654-cf5505315d73_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedging Relationship [Axis]</link:label>
    <link:label id="lab_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_label_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hedging Relationship [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis" xlink:to="lab_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_currency_CHF_d5477b13-b382-43ab-b55b-6e0e1bcec1ca_terseLabel_en-US" xlink:label="lab_currency_CHF" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Switzerland, Francs</link:label>
    <link:label id="lab_currency_CHF_label_en-US" xlink:label="lab_currency_CHF" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Switzerland, Francs</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_currency_CHF" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_CHF"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_currency_CHF" xlink:to="lab_currency_CHF" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NonUsMember_bfc211d3-f617-47b8-b55b-1dfead6a34c8_terseLabel_en-US" xlink:label="lab_us-gaap_NonUsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">ROW [Member]</link:label>
    <link:label id="lab_us-gaap_NonUsMember_label_en-US" xlink:label="lab_us-gaap_NonUsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Non-US [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonUsMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NonUsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NonUsMember" xlink:to="lab_us-gaap_NonUsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SubsequentEventsTextBlock_2f18cfc7-a1b6-4df0-8c94-63997480cd27_terseLabel_en-US" xlink:label="lab_us-gaap_SubsequentEventsTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Subsequent events</link:label>
    <link:label id="lab_us-gaap_SubsequentEventsTextBlock_label_en-US" xlink:label="lab_us-gaap_SubsequentEventsTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Subsequent Events [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventsTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SubsequentEventsTextBlock" xlink:to="lab_us-gaap_SubsequentEventsTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_DerivativeInstrumentNameAxis_256b072f-2a3a-4fd4-97e5-b96137e31028_terseLabel_en-US" xlink:label="lab_amgn_DerivativeInstrumentNameAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instrument, Name [Axis]</link:label>
    <link:label id="lab_amgn_DerivativeInstrumentNameAxis_label_en-US" xlink:label="lab_amgn_DerivativeInstrumentNameAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instrument, Name [Axis]</link:label>
    <link:label id="lab_amgn_DerivativeInstrumentNameAxis_documentation_en-US" xlink:label="lab_amgn_DerivativeInstrumentNameAxis" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instrument, Name</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DerivativeInstrumentNameAxis" xlink:href="amgn-20210930.xsd#amgn_DerivativeInstrumentNameAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_DerivativeInstrumentNameAxis" xlink:to="lab_amgn_DerivativeInstrumentNameAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IntangibleAssetsNetExcludingGoodwill_4ce640fd-9e7a-4c34-aabf-858e33cd6106_verboseLabel_en-US" xlink:label="lab_us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Intangible assets, net</link:label>
    <link:label id="lab_us-gaap_IntangibleAssetsNetExcludingGoodwill_c9fb7fce-03a5-4f82-b0a3-05220282c548_totalLabel_en-US" xlink:label="lab_us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Intangible assets, net</link:label>
    <link:label id="lab_us-gaap_IntangibleAssetsNetExcludingGoodwill_label_en-US" xlink:label="lab_us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Intangible Assets, Net (Excluding Goodwill)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:to="lab_us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ComprehensiveIncomeNetOfTax_76a01241-69d7-4508-a1a4-c2f42b3d1a60_totalLabel_en-US" xlink:label="lab_us-gaap_ComprehensiveIncomeNetOfTax" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Comprehensive income</link:label>
    <link:label id="lab_us-gaap_ComprehensiveIncomeNetOfTax_label_en-US" xlink:label="lab_us-gaap_ComprehensiveIncomeNetOfTax" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Comprehensive Income (Loss), Net of Tax, Attributable to Parent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax" xlink:to="lab_us-gaap_ComprehensiveIncomeNetOfTax" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_OtezlaANDAPatentLitigationMember_d0eeb858-fb9c-4aca-bd88-d2da3db3e37e_terseLabel_en-US" xlink:label="lab_amgn_OtezlaANDAPatentLitigationMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Otezla ANDA Patent Litigation [Member]</link:label>
    <link:label id="lab_amgn_OtezlaANDAPatentLitigationMember_label_en-US" xlink:label="lab_amgn_OtezlaANDAPatentLitigationMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Otezla ANDA Patent Litigation [Member]</link:label>
    <link:label id="lab_amgn_OtezlaANDAPatentLitigationMember_documentation_en-US" xlink:label="lab_amgn_OtezlaANDAPatentLitigationMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Otezla ANDA Patent Litigation</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtezlaANDAPatentLitigationMember" xlink:href="amgn-20210930.xsd#amgn_OtezlaANDAPatentLitigationMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OtezlaANDAPatentLitigationMember" xlink:to="lab_amgn_OtezlaANDAPatentLitigationMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_EquityMethodInvestmentChangeInCarryingValueOther_9ea393af-c074-4189-b5e2-27dc20eaa253_terseLabel_en-US" xlink:label="lab_amgn_EquityMethodInvestmentChangeInCarryingValueOther" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investment, Change In Carrying Value, Other</link:label>
    <link:label id="lab_amgn_EquityMethodInvestmentChangeInCarryingValueOther_label_en-US" xlink:label="lab_amgn_EquityMethodInvestmentChangeInCarryingValueOther" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investment, Change In Carrying Value, Other</link:label>
    <link:label id="lab_amgn_EquityMethodInvestmentChangeInCarryingValueOther_documentation_en-US" xlink:label="lab_amgn_EquityMethodInvestmentChangeInCarryingValueOther" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Method Investment, Change In Carrying Value, Other</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_EquityMethodInvestmentChangeInCarryingValueOther" xlink:href="amgn-20210930.xsd#amgn_EquityMethodInvestmentChangeInCarryingValueOther"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_EquityMethodInvestmentChangeInCarryingValueOther" xlink:to="lab_amgn_EquityMethodInvestmentChangeInCarryingValueOther" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInFinancingActivities_e8e80f76-13fd-4ee4-94f2-575e006d92b8_totalLabel_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net cash used in financing activities</link:label>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInFinancingActivities_label_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Cash Provided by (Used in) Financing Activities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:to="lab_us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_TwoPointFourFivePercentNotesDue2030Member_e906a08c-481b-4a2d-97be-e7f0f634b7c2_terseLabel_en-US" xlink:label="lab_amgn_TwoPointFourFivePercentNotesDue2030Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.45% notes due 2030 (2.45% 2030 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointFourFivePercentNotesDue2030Member_label_en-US" xlink:label="lab_amgn_TwoPointFourFivePercentNotesDue2030Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Four Five Percent Notes Due 2030 [Member]</link:label>
    <link:label id="lab_amgn_TwoPointFourFivePercentNotesDue2030Member_documentation_en-US" xlink:label="lab_amgn_TwoPointFourFivePercentNotesDue2030Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Four Five Percent Notes Due 2030 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointFourFivePercentNotesDue2030Member" xlink:href="amgn-20210930.xsd#amgn_TwoPointFourFivePercentNotesDue2030Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointFourFivePercentNotesDue2030Member" xlink:to="lab_amgn_TwoPointFourFivePercentNotesDue2030Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_6b1b4bb0-dabe-47ea-8e4e-01545b945e4c_verboseLabel_en-US" xlink:label="lab_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Shares used in calculation of earnings per share:</link:label>
    <link:label id="lab_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_3b3f4c95-a5ce-41c3-aad7-4f0a68a7ddf0_terseLabel_en-US" xlink:label="lab_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Shares (Denominator):</link:label>
    <link:label id="lab_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_label_en-US" xlink:label="lab_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Weighted Average Number of Shares Outstanding, Diluted [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:to="lab_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_LossContingencyAppealPeriod_05a0c793-bc0a-4078-9c78-49933b6fa6a0_terseLabel_en-US" xlink:label="lab_amgn_LossContingencyAppealPeriod" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, appeal period</link:label>
    <link:label id="lab_amgn_LossContingencyAppealPeriod_label_en-US" xlink:label="lab_amgn_LossContingencyAppealPeriod" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, appeal period</link:label>
    <link:label id="lab_amgn_LossContingencyAppealPeriod_documentation_en-US" xlink:label="lab_amgn_LossContingencyAppealPeriod" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingency, appeal period</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LossContingencyAppealPeriod" xlink:href="amgn-20210930.xsd#amgn_LossContingencyAppealPeriod"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_LossContingencyAppealPeriod" xlink:to="lab_amgn_LossContingencyAppealPeriod" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncomeLossFromEquityMethodInvestments_ac0a5839-b776-4c06-b96b-02f871eb2625_terseLabel_en-US" xlink:label="lab_us-gaap_IncomeLossFromEquityMethodInvestments" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income (Loss) from Equity Method Investments</link:label>
    <link:label id="lab_us-gaap_IncomeLossFromEquityMethodInvestments_label_en-US" xlink:label="lab_us-gaap_IncomeLossFromEquityMethodInvestments" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income (Loss) from Equity Method Investments</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestments"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncomeLossFromEquityMethodInvestments" xlink:to="lab_us-gaap_IncomeLossFromEquityMethodInvestments" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_FivePointSevenFivePercentNotesDue2040Member_9079c568-493c-4f4f-81e2-9b18c504d635_terseLabel_en-US" xlink:label="lab_amgn_FivePointSevenFivePercentNotesDue2040Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">5.75% notes due 2040 (5.75% 2040 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FivePointSevenFivePercentNotesDue2040Member_label_en-US" xlink:label="lab_amgn_FivePointSevenFivePercentNotesDue2040Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Five Point Seven Five Percent Notes Due 2040 [Member]</link:label>
    <link:label id="lab_amgn_FivePointSevenFivePercentNotesDue2040Member_documentation_en-US" xlink:label="lab_amgn_FivePointSevenFivePercentNotesDue2040Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Five Point Seven Five Percent Notes Due 2040 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointSevenFivePercentNotesDue2040Member" xlink:href="amgn-20210930.xsd#amgn_FivePointSevenFivePercentNotesDue2040Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FivePointSevenFivePercentNotesDue2040Member" xlink:to="lab_amgn_FivePointSevenFivePercentNotesDue2040Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_RecoveryOfDirectCosts_4bd585b9-3c60-4b36-adf0-7835aacfbb2b_terseLabel_en-US" xlink:label="lab_us-gaap_RecoveryOfDirectCosts" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net costs recovered</link:label>
    <link:label id="lab_us-gaap_RecoveryOfDirectCosts_label_en-US" xlink:label="lab_us-gaap_RecoveryOfDirectCosts" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Recovery of Direct Costs</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RecoveryOfDirectCosts" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RecoveryOfDirectCosts"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_RecoveryOfDirectCosts" xlink:to="lab_us-gaap_RecoveryOfDirectCosts" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_BusinessAcquisitionAcquireeDomain_a8ba2b30-396d-465b-9318-ea0701276a86_terseLabel_en-US" xlink:label="lab_us-gaap_BusinessAcquisitionAcquireeDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Acquisition, Acquiree [Domain]</link:label>
    <link:label id="lab_us-gaap_BusinessAcquisitionAcquireeDomain_label_en-US" xlink:label="lab_us-gaap_BusinessAcquisitionAcquireeDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Business Acquisition, Acquiree [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain" xlink:to="lab_us-gaap_BusinessAcquisitionAcquireeDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_KyprolisMember_b77247f8-eab8-45de-ac46-beb2ae317a8f_terseLabel_en-US" xlink:label="lab_amgn_KyprolisMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">KYPROLIS&#174; (carfilzomib) [Member]</link:label>
    <link:label id="lab_amgn_KyprolisMember_label_en-US" xlink:label="lab_amgn_KyprolisMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Kyprolis [Member]</link:label>
    <link:label id="lab_amgn_KyprolisMember_documentation_en-US" xlink:label="lab_amgn_KyprolisMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Kyprolis [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_KyprolisMember" xlink:href="amgn-20210930.xsd#amgn_KyprolisMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_KyprolisMember" xlink:to="lab_amgn_KyprolisMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueDisclosuresTextBlock_2417719d-5dde-4a9e-a1cb-3c5e00afe784_verboseLabel_en-US" xlink:label="lab_us-gaap_FairValueDisclosuresTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair value measurement</link:label>
    <link:label id="lab_us-gaap_FairValueDisclosuresTextBlock_label_en-US" xlink:label="lab_us-gaap_FairValueDisclosuresTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Disclosures [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueDisclosuresTextBlock" xlink:to="lab_us-gaap_FairValueDisclosuresTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccountsPayableCurrent_9c0f61fa-1597-4ae3-b0c8-d4c1d12f9e7e_verboseLabel_en-US" xlink:label="lab_us-gaap_AccountsPayableCurrent" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accounts payable</link:label>
    <link:label id="lab_us-gaap_AccountsPayableCurrent_label_en-US" xlink:label="lab_us-gaap_AccountsPayableCurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accounts Payable, Current</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccountsPayableCurrent" xlink:to="lab_us-gaap_AccountsPayableCurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtSecuritiesPayableMember_5f6bce92-ece8-4938-b1aa-aed193f9a4cb_terseLabel_en-US" xlink:label="lab_us-gaap_DebtSecuritiesPayableMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities Payable [Member]</link:label>
    <link:label id="lab_us-gaap_DebtSecuritiesPayableMember_label_en-US" xlink:label="lab_us-gaap_DebtSecuritiesPayableMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities Payable [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesPayableMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesPayableMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtSecuritiesPayableMember" xlink:to="lab_us-gaap_DebtSecuritiesPayableMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DepreciationDepletionAndAmortization_d4ab9d02-337f-47c8-9398-5f6e4d510119_verboseLabel_en-US" xlink:label="lab_us-gaap_DepreciationDepletionAndAmortization" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Depreciation, amortization and other</link:label>
    <link:label id="lab_us-gaap_DepreciationDepletionAndAmortization_label_en-US" xlink:label="lab_us-gaap_DepreciationDepletionAndAmortization" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Depreciation, Depletion and Amortization</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DepreciationDepletionAndAmortization" xlink:to="lab_us-gaap_DepreciationDepletionAndAmortization" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_f8870586-a8a6-495b-97e8-dc1e3236d32f_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair value of each major class of financial assets and liabilities measured at fair value on a recurring basis</link:label>
    <link:label id="lab_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:to="lab_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_00b4e2ae-a25f-434d-8200-163d40d57060_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total estimated amortization of finite-lived intangible assets for 2024</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Year Three</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntitiesTable_87d94d5e-d293-4652-9383-b15be4c362a3_terseLabel_en-US" xlink:label="lab_dei_EntitiesTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entities [Table]</link:label>
    <link:label id="lab_dei_EntitiesTable_label_en-US" xlink:label="lab_dei_EntitiesTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entities [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntitiesTable" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntitiesTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntitiesTable" xlink:to="lab_dei_EntitiesTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccumulatedOtherComprehensiveIncomeMember_b42f6851-8a26-48e5-98e5-89e3d76f60c9_terseLabel_en-US" xlink:label="lab_us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated other comprehensive loss [Member]</link:label>
    <link:label id="lab_us-gaap_AccumulatedOtherComprehensiveIncomeMember_d0dd40e2-8a6b-4ad4-b926-83f567ee8d21_verboseLabel_en-US" xlink:label="lab_us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">AOCI [Member]</link:label>
    <link:label id="lab_us-gaap_AccumulatedOtherComprehensiveIncomeMember_label_en-US" xlink:label="lab_us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">AOCI Attributable to Parent [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:to="lab_us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_35f3f52e-cadd-42ce-95dd-b2dc3516f072_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total estimated amortization of finite-lived intangible assets for the six months ending December 31, 2021</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Remainder of Fiscal Year</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncreaseDecreaseInInventories_c3ddefbe-01e7-4d0a-bee6-67ca72832a74_negatedLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInInventories" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Inventories</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInInventories_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInInventories" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) in Inventories</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInInventories"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncreaseDecreaseInInventories" xlink:to="lab_us-gaap_IncreaseDecreaseInInventories" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommonStockSharesOutstanding_073bb2a3-0e2f-4d9f-b94c-0c85e4c3f10d_verboseLabel_en-US" xlink:label="lab_us-gaap_CommonStockSharesOutstanding" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock and additional paid-in capital, shares outstanding</link:label>
    <link:label id="lab_us-gaap_CommonStockSharesOutstanding_07b0feea-fe46-4e84-b48a-0f7052c91f8c_periodStartLabel_en-US" xlink:label="lab_us-gaap_CommonStockSharesOutstanding" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Beginning Balance, Shares</link:label>
    <link:label id="lab_us-gaap_CommonStockSharesOutstanding_d6d462f5-51bb-4167-8f44-ea57621830fd_periodEndLabel_en-US" xlink:label="lab_us-gaap_CommonStockSharesOutstanding" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Ending Balance, Shares</link:label>
    <link:label id="lab_us-gaap_CommonStockSharesOutstanding_label_en-US" xlink:label="lab_us-gaap_CommonStockSharesOutstanding" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common Stock, Shares, Outstanding</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommonStockSharesOutstanding" xlink:to="lab_us-gaap_CommonStockSharesOutstanding" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_a981620f-f66d-4e09-9148-9bf61f11eaae_terseLabel_en-US" xlink:label="lab_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Instruments [Domain]</link:label>
    <link:label id="lab_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_label_en-US" xlink:label="lab_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Financial Instruments [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain" xlink:to="lab_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax_5ffcd7c2-a372-4c51-9a3d-7b0b2ead33e7_verboseLabel_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total unrealized gains (losses)</link:label>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax_label_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification, before Tax</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" xlink:to="lab_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeTable_16fcbcd7-00fa-4dc7-9fcd-4db0ef56baa5_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative [Table]</link:label>
    <link:label id="lab_us-gaap_DerivativeTable_label_en-US" xlink:label="lab_us-gaap_DerivativeTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeTable" xlink:to="lab_us-gaap_DerivativeTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AlternativeInvestment_5c0ad9b4-f96b-43e4-9a82-89c532f72ec3_terseLabel_en-US" xlink:label="lab_us-gaap_AlternativeInvestment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Alternative investments</link:label>
    <link:label id="lab_us-gaap_AlternativeInvestment_label_en-US" xlink:label="lab_us-gaap_AlternativeInvestment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Alternative Investment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AlternativeInvestment" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AlternativeInvestment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AlternativeInvestment" xlink:to="lab_us-gaap_AlternativeInvestment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CostOfGoodsAndServicesSold_8332c840-3187-46a4-bcc4-8a3a918b7548_terseLabel_en-US" xlink:label="lab_us-gaap_CostOfGoodsAndServicesSold" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cost of sales</link:label>
    <link:label id="lab_us-gaap_CostOfGoodsAndServicesSold_label_en-US" xlink:label="lab_us-gaap_CostOfGoodsAndServicesSold" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cost of Goods and Services Sold</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CostOfGoodsAndServicesSold" xlink:to="lab_us-gaap_CostOfGoodsAndServicesSold" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_RevenuesAbstract_acc1d020-adec-4a6b-a8f6-7056fc3aa6e4_verboseLabel_en-US" xlink:label="lab_us-gaap_RevenuesAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Revenues:</link:label>
    <link:label id="lab_us-gaap_RevenuesAbstract_label_en-US" xlink:label="lab_us-gaap_RevenuesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Revenues [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenuesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenuesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_RevenuesAbstract" xlink:to="lab_us-gaap_RevenuesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_3ae2a995-f6bf-4453-9d44-7e026e019f7f_terseLabel_en-US" xlink:label="lab_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">1.25% &#8364;1,250 million notes due 2022 (1.25% 2022 euro Notes) [Member]</link:label>
    <link:label id="lab_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_label_en-US" xlink:label="lab_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">One Point Two Five Percent Euro Notes due Two Zero Two Two [Member]</link:label>
    <link:label id="lab_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_documentation_en-US" xlink:label="lab_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">One Point Two Five Percent Euro Notes due Two Zero Two Two [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember" xlink:href="amgn-20210930.xsd#amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember" xlink:to="lab_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_3865e03a-f39c-4cb7-89b2-131a6a183a1b_terseLabel_en-US" xlink:label="lab_amgn_ThreePointSixTwoFivePercentNotesDue2024Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">3.625% notes due 2024 (3.625% 2024 Notes) [Member]</link:label>
    <link:label id="lab_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_label_en-US" xlink:label="lab_amgn_ThreePointSixTwoFivePercentNotesDue2024Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point Six Two Five Percent Notes Due 2024 [Member]</link:label>
    <link:label id="lab_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_documentation_en-US" xlink:label="lab_amgn_ThreePointSixTwoFivePercentNotesDue2024Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point Six Two Five Percent Notes Due 2024 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointSixTwoFivePercentNotesDue2024Member" xlink:href="amgn-20210930.xsd#amgn_ThreePointSixTwoFivePercentNotesDue2024Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ThreePointSixTwoFivePercentNotesDue2024Member" xlink:to="lab_amgn_ThreePointSixTwoFivePercentNotesDue2024Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent_58e4720f-784f-4c25-95ec-56e242946413_terseLabel_en-US" xlink:label="lab_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Unrealized gains</link:label>
    <link:label id="lab_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent_label_en-US" xlink:label="lab_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">OCI, before Reclassifications, before Tax, Attributable to Parent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent" xlink:to="lab_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ProductAndServiceOtherMember_564fe757-eb4c-461c-bca5-55cdb7c5077f_terseLabel_en-US" xlink:label="lab_us-gaap_ProductAndServiceOtherMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other revenues [Member]</link:label>
    <link:label id="lab_us-gaap_ProductAndServiceOtherMember_label_en-US" xlink:label="lab_us-gaap_ProductAndServiceOtherMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Product and Service, Other [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductAndServiceOtherMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductAndServiceOtherMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ProductAndServiceOtherMember" xlink:to="lab_us-gaap_ProductAndServiceOtherMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_A2030And2021NoteHedgesMember_a7700b9f-4a51-4f6f-91fb-ca96c20c0755_terseLabel_en-US" xlink:label="lab_amgn_A2030And2021NoteHedgesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2030 And 2021 Note Hedges</link:label>
    <link:label id="lab_amgn_A2030And2021NoteHedgesMember_label_en-US" xlink:label="lab_amgn_A2030And2021NoteHedgesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2030 And 2021 Note Hedges [Member]</link:label>
    <link:label id="lab_amgn_A2030And2021NoteHedgesMember_documentation_en-US" xlink:label="lab_amgn_A2030And2021NoteHedgesMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2030 And 2021 Note Hedges</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_A2030And2021NoteHedgesMember" xlink:href="amgn-20210930.xsd#amgn_A2030And2021NoteHedgesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_A2030And2021NoteHedgesMember" xlink:to="lab_amgn_A2030And2021NoteHedgesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncomeStatementLocationDomain_165e2194-a005-49fa-b895-0190e5433ca3_terseLabel_en-US" xlink:label="lab_us-gaap_IncomeStatementLocationDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income Statement Location [Domain]</link:label>
    <link:label id="lab_us-gaap_IncomeStatementLocationDomain_label_en-US" xlink:label="lab_us-gaap_IncomeStatementLocationDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income Statement Location [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncomeStatementLocationDomain" xlink:to="lab_us-gaap_IncomeStatementLocationDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1_ad1045e0-a813-4213-b0ec-874d9d60f907_terseLabel_en-US" xlink:label="lab_us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Noncash or Part Noncash Acquisition, Investments Acquired</link:label>
    <link:label id="lab_us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1_label_en-US" xlink:label="lab_us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Noncash or Part Noncash Acquisition, Investments Acquired</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1" xlink:to="lab_us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleTable_2b1eb2da-dddd-4f22-8cab-e1ffb4f747cd_terseLabel_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale [Table]</link:label>
    <link:label id="lab_us-gaap_DebtSecuritiesAvailableForSaleTable_label_en-US" xlink:label="lab_us-gaap_DebtSecuritiesAvailableForSaleTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-sale [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleTable" xlink:to="lab_us-gaap_DebtSecuritiesAvailableForSaleTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LossContingenciesLineItems_e99d0155-15d4-4d20-b232-96086b29eaf6_terseLabel_en-US" xlink:label="lab_us-gaap_LossContingenciesLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingencies [Line Items]</link:label>
    <link:label id="lab_us-gaap_LossContingenciesLineItems_label_en-US" xlink:label="lab_us-gaap_LossContingenciesLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingencies [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingenciesLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LossContingenciesLineItems" xlink:to="lab_us-gaap_LossContingenciesLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PropertyPlantAndEquipmentNet_0a434b9c-ae0c-4c35-886f-61fc07b27a05_verboseLabel_en-US" xlink:label="lab_us-gaap_PropertyPlantAndEquipmentNet" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Property, plant and equipment, net</link:label>
    <link:label id="lab_us-gaap_PropertyPlantAndEquipmentNet_label_en-US" xlink:label="lab_us-gaap_PropertyPlantAndEquipmentNet" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Property, Plant and Equipment, Net</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet" xlink:to="lab_us-gaap_PropertyPlantAndEquipmentNet" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_OnePointSixFivePercent2028NotesMember_d6be08fe-880a-4f50-bb2d-e8c7d51fd939_terseLabel_en-US" xlink:label="lab_amgn_OnePointSixFivePercent2028NotesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">1.65% notes due 2028 (1.65% 2028 Notes) [Member}</link:label>
    <link:label id="lab_amgn_OnePointSixFivePercent2028NotesMember_label_en-US" xlink:label="lab_amgn_OnePointSixFivePercent2028NotesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">One point six five percent 2028 Notes [Member]</link:label>
    <link:label id="lab_amgn_OnePointSixFivePercent2028NotesMember_documentation_en-US" xlink:label="lab_amgn_OnePointSixFivePercent2028NotesMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">One point six five percent 2028 Notes</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointSixFivePercent2028NotesMember" xlink:href="amgn-20210930.xsd#amgn_OnePointSixFivePercent2028NotesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OnePointSixFivePercent2028NotesMember" xlink:to="lab_amgn_OnePointSixFivePercent2028NotesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherLiabilitiesNoncurrent_c102630e-2f7c-45e6-8cc3-5cc69bcbd594_verboseLabel_en-US" xlink:label="lab_us-gaap_OtherLiabilitiesNoncurrent" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other noncurrent liabilities</link:label>
    <link:label id="lab_us-gaap_OtherLiabilitiesNoncurrent_label_en-US" xlink:label="lab_us-gaap_OtherLiabilitiesNoncurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Liabilities, Noncurrent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherLiabilitiesNoncurrent" xlink:to="lab_us-gaap_OtherLiabilitiesNoncurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ResidentialMortgageBackedSecuritiesMember_393ae987-e3d2-4f0a-ac15-a4b2d06575e9_terseLabel_en-US" xlink:label="lab_us-gaap_ResidentialMortgageBackedSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Residential mortgage-backed securities [Member]</link:label>
    <link:label id="lab_us-gaap_ResidentialMortgageBackedSecuritiesMember_label_en-US" xlink:label="lab_us-gaap_ResidentialMortgageBackedSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Residential Mortgage Backed Securities [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResidentialMortgageBackedSecuritiesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember" xlink:to="lab_us-gaap_ResidentialMortgageBackedSecuritiesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge_442f69b3-e2e2-4798-a577-09765a194921_terseLabel_en-US" xlink:label="lab_us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Length of time hedged in foreign currency contracts (or less)</link:label>
    <link:label id="lab_us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge_label_en-US" xlink:label="lab_us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maximum Length of Time, Foreign Currency Cash Flow Hedge</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge" xlink:to="lab_us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ProposedAdditionalIncomeTax_4fbbdeaf-73aa-4a0a-836d-1099bcaf4819_terseLabel_en-US" xlink:label="lab_amgn_ProposedAdditionalIncomeTax" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proposed additional income tax</link:label>
    <link:label id="lab_amgn_ProposedAdditionalIncomeTax_label_en-US" xlink:label="lab_amgn_ProposedAdditionalIncomeTax" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proposed additional income tax</link:label>
    <link:label id="lab_amgn_ProposedAdditionalIncomeTax_documentation_en-US" xlink:label="lab_amgn_ProposedAdditionalIncomeTax" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proposed additional income tax</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ProposedAdditionalIncomeTax" xlink:href="amgn-20210930.xsd#amgn_ProposedAdditionalIncomeTax"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ProposedAdditionalIncomeTax" xlink:to="lab_amgn_ProposedAdditionalIncomeTax" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_fda21988-bde3-4ff0-8832-e0af5c3e6032_terseLabel_en-US" xlink:label="lab_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.60% notes due 2026 (2.60% 2026 notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_label_en-US" xlink:label="lab_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Six Zero Notes Due Two Zero Two Six [Member]</link:label>
    <link:label id="lab_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_documentation_en-US" xlink:label="lab_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Point Six Zero Notes Due Two Zero Two Six [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember" xlink:href="amgn-20210930.xsd#amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember" xlink:to="lab_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfDebtInstrumentsTextBlock_9d4bdb8a-57e8-4267-aef7-e94928b7f924_verboseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfDebtInstrumentsTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of borrowings</link:label>
    <link:label id="lab_us-gaap_ScheduleOfDebtInstrumentsTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfDebtInstrumentsTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Long-term Debt Instruments [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfDebtInstrumentsTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock" xlink:to="lab_us-gaap_ScheduleOfDebtInstrumentsTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtInstrumentLineItems_9d7afc20-7a85-4f5a-a167-00becb7d4cec_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument [Line Items]</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentLineItems_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentLineItems" xlink:to="lab_us-gaap_DebtInstrumentLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_RepaymentsOfLongTermDebt_3e7706c5-8d7c-4ab7-9332-d1131a4ffc62_negatedLabel_en-US" xlink:label="lab_us-gaap_RepaymentsOfLongTermDebt" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Repayment of debt</link:label>
    <link:label id="lab_us-gaap_RepaymentsOfLongTermDebt_label_en-US" xlink:label="lab_us-gaap_RepaymentsOfLongTermDebt" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Repayments of Long-term Debt</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_RepaymentsOfLongTermDebt" xlink:to="lab_us-gaap_RepaymentsOfLongTermDebt" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EarningsPerShareAbstract_98552bd2-08bb-4ff1-a237-c8b01d21c3fe_verboseLabel_en-US" xlink:label="lab_us-gaap_EarningsPerShareAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Earnings per share:</link:label>
    <link:label id="lab_us-gaap_EarningsPerShareAbstract_f6cfec69-2f64-4344-bb78-f2276081aebd_terseLabel_en-US" xlink:label="lab_us-gaap_EarningsPerShareAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Earnings Per Share [Abstract]</link:label>
    <link:label id="lab_us-gaap_EarningsPerShareAbstract_label_en-US" xlink:label="lab_us-gaap_EarningsPerShareAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Earnings Per Share [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EarningsPerShareAbstract" xlink:to="lab_us-gaap_EarningsPerShareAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_DerivativeAssetsFairValueDisclosureAbstract_11ee1104-699f-4546-bbc4-ee8d36ea6eb3_verboseLabel_en-US" xlink:label="lab_amgn_DerivativeAssetsFairValueDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivatives:</link:label>
    <link:label id="lab_amgn_DerivativeAssetsFairValueDisclosureAbstract_label_en-US" xlink:label="lab_amgn_DerivativeAssetsFairValueDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Assets Fair Value Disclosure [Abstract]</link:label>
    <link:label id="lab_amgn_DerivativeAssetsFairValueDisclosureAbstract_documentation_en-US" xlink:label="lab_amgn_DerivativeAssetsFairValueDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative assets.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DerivativeAssetsFairValueDisclosureAbstract" xlink:href="amgn-20210930.xsd#amgn_DerivativeAssetsFairValueDisclosureAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_DerivativeAssetsFairValueDisclosureAbstract" xlink:to="lab_amgn_DerivativeAssetsFairValueDisclosureAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount_026d972a-6928-4ed4-9a0c-9b6aec94a71a_terseLabel_en-US" xlink:label="lab_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Securities without Readily Determinable Fair Value, Upward Price Adjustment, Annual Amount</link:label>
    <link:label id="lab_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount_label_en-US" xlink:label="lab_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Securities without Readily Determinable Fair Value, Upward Price Adjustment, Annual Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount" xlink:to="lab_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_AccumulatedOtherAdjustmentAttributabletoParentMember_92a44abb-4c8b-4b3a-855f-d2a5d9a5b795_terseLabel_en-US" xlink:label="lab_amgn_AccumulatedOtherAdjustmentAttributabletoParentMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other [Member]</link:label>
    <link:label id="lab_amgn_AccumulatedOtherAdjustmentAttributabletoParentMember_label_en-US" xlink:label="lab_amgn_AccumulatedOtherAdjustmentAttributabletoParentMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated Other Adjustment Attributable to Parent [Member]</link:label>
    <link:label id="lab_amgn_AccumulatedOtherAdjustmentAttributabletoParentMember_documentation_en-US" xlink:label="lab_amgn_AccumulatedOtherAdjustmentAttributabletoParentMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated Other Adjustment Attributable to Parent [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AccumulatedOtherAdjustmentAttributabletoParentMember" xlink:href="amgn-20210930.xsd#amgn_AccumulatedOtherAdjustmentAttributabletoParentMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_AccumulatedOtherAdjustmentAttributabletoParentMember" xlink:to="lab_amgn_AccumulatedOtherAdjustmentAttributabletoParentMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_50017108-7d21-4f7b-b60b-ecdad5759dbc_terseLabel_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">(Losses) gains on foreign currency translation</link:label>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_4602fb2e-b4d3-4df5-adf7-8218dd5d5e18_verboseLabel_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Foreign currency translation adjustments</link:label>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_label_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" xlink:to="lab_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss_62da51cc-ca39-4b7d-aa9a-f4b79c422f35_terseLabel_en-US" xlink:label="lab_us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Securities, FV-NI, Unrealized Gain (Loss)</link:label>
    <link:label id="lab_us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss_label_en-US" xlink:label="lab_us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Equity Securities, FV-NI, Unrealized Gain (Loss)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss" xlink:to="lab_us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_DocumentQuarterlyReport_a6d74eb8-aef4-4d9f-a633-920b70eb55f4_terseLabel_en-US" xlink:label="lab_dei_DocumentQuarterlyReport" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Quarterly Report</link:label>
    <link:label id="lab_dei_DocumentQuarterlyReport_label_en-US" xlink:label="lab_dei_DocumentQuarterlyReport" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Quarterly Report</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentQuarterlyReport" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentQuarterlyReport"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_DocumentQuarterlyReport" xlink:to="lab_dei_DocumentQuarterlyReport" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncreaseDecreaseInOtherOperatingAssets_e1290de3-41f1-4f25-bcc2-16d79caf042c_negatedLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOtherOperatingAssets" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other assets</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInOtherOperatingAssets_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOtherOperatingAssets" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) in Other Operating Assets</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets" xlink:to="lab_us-gaap_IncreaseDecreaseInOtherOperatingAssets" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_OtezlaMember_ea73b6b0-571f-423b-9eeb-671e94e518e8_terseLabel_en-US" xlink:label="lab_amgn_OtezlaMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Otezla (apremilast) [Member]</link:label>
    <link:label id="lab_amgn_OtezlaMember_label_en-US" xlink:label="lab_amgn_OtezlaMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Otezla [Member]</link:label>
    <link:label id="lab_amgn_OtezlaMember_documentation_en-US" xlink:label="lab_amgn_OtezlaMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Otezla [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtezlaMember" xlink:href="amgn-20210930.xsd#amgn_OtezlaMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OtezlaMember" xlink:to="lab_amgn_OtezlaMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ForeignExchangeContractMember_06ff89c4-b79a-4025-8e7a-25758843d937_terseLabel_en-US" xlink:label="lab_us-gaap_ForeignExchangeContractMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Foreign currency contract [Member]</link:label>
    <link:label id="lab_us-gaap_ForeignExchangeContractMember_eb4b38f4-6276-45ad-9b35-57b4014f3bfb_verboseLabel_en-US" xlink:label="lab_us-gaap_ForeignExchangeContractMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Foreign currency contracts [Member]</link:label>
    <link:label id="lab_us-gaap_ForeignExchangeContractMember_label_en-US" xlink:label="lab_us-gaap_ForeignExchangeContractMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Foreign Exchange Contract [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ForeignExchangeContractMember" xlink:to="lab_us-gaap_ForeignExchangeContractMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_473b6836-8b7f-4b1c-b2a7-41bde6b53a39_verboseLabel_en-US" xlink:label="lab_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proceeds from sales of marketable securities</link:label>
    <link:label id="lab_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_label_en-US" xlink:label="lab_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proceeds from Sale of Debt Securities, Available-for-sale</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt" xlink:to="lab_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityCommonStockSharesOutstanding_6f1b038c-d7e9-49dd-adc8-73aefb95d6f5_terseLabel_en-US" xlink:label="lab_dei_EntityCommonStockSharesOutstanding" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Common Stock, Shares Outstanding</link:label>
    <link:label id="lab_dei_EntityCommonStockSharesOutstanding_label_en-US" xlink:label="lab_dei_EntityCommonStockSharesOutstanding" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Common Stock, Shares Outstanding</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCommonStockSharesOutstanding" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCommonStockSharesOutstanding"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityCommonStockSharesOutstanding" xlink:to="lab_dei_EntityCommonStockSharesOutstanding" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_445719f9-479d-44d8-a762-8ba492ed0173_terseLabel_en-US" xlink:label="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification out of Accumulated Other Comprehensive Income [Table]</link:label>
    <link:label id="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_label_en-US" xlink:label="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification out of Accumulated Other Comprehensive Income [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable" xlink:to="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_0c6026c3-c99b-4486-9351-f62ce4c96d57_verboseLabel_en-US" xlink:label="lab_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivatives:</link:label>
    <link:label id="lab_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_label_en-US" xlink:label="lab_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Financial Instruments Liabilities Fair Value Disclosure [Abstract]</link:label>
    <link:label id="lab_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_documentation_en-US" xlink:label="lab_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative financial instruments liabilities fair value disclosure.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract" xlink:href="amgn-20210930.xsd#amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract" xlink:to="lab_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CostsAndExpensesAbstract_08c3b433-8144-4952-b6f1-0fc0ae9f7d2d_verboseLabel_en-US" xlink:label="lab_us-gaap_CostsAndExpensesAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Operating expenses:</link:label>
    <link:label id="lab_us-gaap_CostsAndExpensesAbstract_label_en-US" xlink:label="lab_us-gaap_CostsAndExpensesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Costs and Expenses [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpensesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostsAndExpensesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CostsAndExpensesAbstract" xlink:to="lab_us-gaap_CostsAndExpensesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LongTermDebtNoncurrent_b06a5660-01af-43ef-bb6b-6808a8048d78_verboseLabel_en-US" xlink:label="lab_us-gaap_LongTermDebtNoncurrent" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term debt</link:label>
    <link:label id="lab_us-gaap_LongTermDebtNoncurrent_6878d4b8-4f54-4a23-abad-608e7c18a501_terseLabel_en-US" xlink:label="lab_us-gaap_LongTermDebtNoncurrent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total long-term debt</link:label>
    <link:label id="lab_us-gaap_LongTermDebtNoncurrent_label_en-US" xlink:label="lab_us-gaap_LongTermDebtNoncurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term Debt, Excluding Current Maturities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LongTermDebtNoncurrent" xlink:to="lab_us-gaap_LongTermDebtNoncurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LiabilitiesFairValueDisclosureAbstract_023457b7-15d9-4239-9f8b-de37b751d70d_verboseLabel_en-US" xlink:label="lab_us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liabilities:</link:label>
    <link:label id="lab_us-gaap_LiabilitiesFairValueDisclosureAbstract_label_en-US" xlink:label="lab_us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liabilities, Fair Value Disclosure [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosureAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:to="lab_us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_210471c5-beee-4a8b-9dc7-41b497780944_terseLabel_en-US" xlink:label="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.00% &#8364;750 million notes due 2026 (2.00% 2026 euro Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_fdcca7b1-d125-4513-b955-985a1d472770_verboseLabel_en-US" xlink:label="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">2.00% 2026 euro Notes [Member]</link:label>
    <link:label id="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_label_en-US" xlink:label="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Percent Euro Notes Due Two Thousand Twenty Six [Member]</link:label>
    <link:label id="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_documentation_en-US" xlink:label="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Two Percent Euro Notes Due Two Thousand Twenty Six [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember" xlink:href="amgn-20210930.xsd#amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember" xlink:to="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_DocumentFiscalPeriodFocus_7af21240-54f8-48c0-96fa-449a3d0c69e8_terseLabel_en-US" xlink:label="lab_dei_DocumentFiscalPeriodFocus" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Fiscal Period Focus</link:label>
    <link:label id="lab_dei_DocumentFiscalPeriodFocus_label_en-US" xlink:label="lab_dei_DocumentFiscalPeriodFocus" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Document Fiscal Period Focus</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalPeriodFocus" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentFiscalPeriodFocus"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_DocumentFiscalPeriodFocus" xlink:to="lab_dei_DocumentFiscalPeriodFocus" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_EffectiveIncomeTaxRateContinuingOperations_01f708ae-856c-4ff4-988b-ad828697141c_terseLabel_en-US" xlink:label="lab_us-gaap_EffectiveIncomeTaxRateContinuingOperations" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Effective income tax rate</link:label>
    <link:label id="lab_us-gaap_EffectiveIncomeTaxRateContinuingOperations_label_en-US" xlink:label="lab_us-gaap_EffectiveIncomeTaxRateContinuingOperations" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Effective Income Tax Rate Reconciliation, Percent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperations"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations" xlink:to="lab_us-gaap_EffectiveIncomeTaxRateContinuingOperations" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_4186fd14-d162-4a60-955c-b81ccfe6a792_terseLabel_en-US" xlink:label="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification out of Accumulated Other Comprehensive Income [Domain]</link:label>
    <link:label id="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_label_en-US" xlink:label="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification out of Accumulated Other Comprehensive Income [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain" xlink:to="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InvestmentTypeCategorizationMember_c65f1833-f844-4bad-b7a9-93f9f8992f46_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentTypeCategorizationMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments [Domain]</link:label>
    <link:label id="lab_us-gaap_InvestmentTypeCategorizationMember_label_en-US" xlink:label="lab_us-gaap_InvestmentTypeCategorizationMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Investments [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeCategorizationMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentTypeCategorizationMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember" xlink:to="lab_us-gaap_InvestmentTypeCategorizationMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_512665d6-d19e-4742-983a-d1b0570cbfaa_periodStartLabel_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash and cash equivalents at beginning of period</link:label>
    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_0c330245-74a7-46ad-9f06-73e996fa367b_periodEndLabel_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash and cash equivalents at end of period</link:label>
    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_label_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:to="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:type="arc" order="1"/>
    <link:label id="lab_country_US_cc152072-0f47-4e0d-9bbe-a632e91f402a_terseLabel_en-US" xlink:label="lab_country_US" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">US [Member]</link:label>
    <link:label id="lab_country_US_label_en-US" xlink:label="lab_country_US" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">UNITED STATES</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_country_US" xlink:href="https://xbrl.sec.gov/country/2021/country-2021.xsd#country_US"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_country_US" xlink:to="lab_country_US" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommonStockParOrStatedValuePerShare_2c328e8c-5af6-48a5-81d7-e793dab86519_verboseLabel_en-US" xlink:label="lab_us-gaap_CommonStockParOrStatedValuePerShare" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock and additional paid-in capital, par value (in usd per share)</link:label>
    <link:label id="lab_us-gaap_CommonStockParOrStatedValuePerShare_label_en-US" xlink:label="lab_us-gaap_CommonStockParOrStatedValuePerShare" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common Stock, Par or Stated Value Per Share</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommonStockParOrStatedValuePerShare" xlink:to="lab_us-gaap_CommonStockParOrStatedValuePerShare" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember_1254bc51-8178-4425-b2e0-44a2a61b0b4f_terseLabel_en-US" xlink:label="lab_amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Research and Development Technology Rights [Member]</link:label>
    <link:label id="lab_amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember_label_en-US" xlink:label="lab_amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Acquired Research And Development Technology Rights [Member]</link:label>
    <link:label id="lab_amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember_documentation_en-US" xlink:label="lab_amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Acquired research and development technology rights.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember" xlink:href="amgn-20210930.xsd#amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember" xlink:to="lab_amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AssetsCurrentAbstract_de94eca1-3c7d-41f2-ae46-5d8cbe4c1305_verboseLabel_en-US" xlink:label="lab_us-gaap_AssetsCurrentAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current assets:</link:label>
    <link:label id="lab_us-gaap_AssetsCurrentAbstract_label_en-US" xlink:label="lab_us-gaap_AssetsCurrentAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Assets, Current [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrentAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsCurrentAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AssetsCurrentAbstract" xlink:to="lab_us-gaap_AssetsCurrentAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_5e7421bd-0adc-4035-8c9c-268defc16501_terseLabel_en-US" xlink:label="lab_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Comprehensive Income [Abstract]</link:label>
    <link:label id="lab_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_label_en-US" xlink:label="lab_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Comprehensive Income [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:to="lab_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_be360081-08e2-4ee8-96f7-7ca45dac1c41_verboseLabel_en-US" xlink:label="lab_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other</link:label>
    <link:label id="lab_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_label_en-US" xlink:label="lab_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Proceeds from (Payments for) Other Financing Activities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromPaymentsForOtherFinancingActivities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities" xlink:to="lab_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsGross_b0354011-a251-443b-b6ad-1839ecd32ce1_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsGross" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Gross carrying amounts</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsGross_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsGross" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Assets, Gross</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsGross" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsGross" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityCentralIndexKey_8f7a6583-f43a-48f9-94ec-d1fad4493505_terseLabel_en-US" xlink:label="lab_dei_EntityCentralIndexKey" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Central Index Key</link:label>
    <link:label id="lab_dei_EntityCentralIndexKey_label_en-US" xlink:label="lab_dei_EntityCentralIndexKey" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Central Index Key</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCentralIndexKey"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityCentralIndexKey" xlink:to="lab_dei_EntityCentralIndexKey" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LondonInterbankOfferedRateLIBORMember_dff26ec2-f746-4874-9f6c-bb0b324db7bd_terseLabel_en-US" xlink:label="lab_us-gaap_LondonInterbankOfferedRateLIBORMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">London Interbank Offered Rate (LIBOR) [Member]</link:label>
    <link:label id="lab_us-gaap_LondonInterbankOfferedRateLIBORMember_label_en-US" xlink:label="lab_us-gaap_LondonInterbankOfferedRateLIBORMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">London Interbank Offered Rate (LIBOR) [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LondonInterbankOfferedRateLIBORMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LondonInterbankOfferedRateLIBORMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LondonInterbankOfferedRateLIBORMember" xlink:to="lab_us-gaap_LondonInterbankOfferedRateLIBORMember" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_SecurityExchangeName_d527ce8e-1c3d-44f5-8a32-91cec8cfce09_terseLabel_en-US" xlink:label="lab_dei_SecurityExchangeName" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Security Exchange Name</link:label>
    <link:label id="lab_dei_SecurityExchangeName_label_en-US" xlink:label="lab_dei_SecurityExchangeName" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Security Exchange Name</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_SecurityExchangeName"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_SecurityExchangeName" xlink:to="lab_dei_SecurityExchangeName" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_f925d049-595d-4d94-b5fa-f504830ccdd0_terseLabel_en-US" xlink:label="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated Other Comprehensive Income (Loss) [Line Items]</link:label>
    <link:label id="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_label_en-US" xlink:label="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated Other Comprehensive Income (Loss) [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems" xlink:to="lab_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent_bfea0bba-797b-4039-8947-7ed08dd9806b_terseLabel_en-US" xlink:label="lab_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification adjustments to income</link:label>
    <link:label id="lab_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent_label_en-US" xlink:label="lab_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification from AOCI, Current Period, before Tax, Attributable to Parent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" xlink:to="lab_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CashAndCashEquivalentsFairValueDisclosure_6eb9eff5-69b4-4aea-98d5-6c7e2315e68d_terseLabel_en-US" xlink:label="lab_us-gaap_CashAndCashEquivalentsFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash and cash equivalents</link:label>
    <link:label id="lab_us-gaap_CashAndCashEquivalentsFairValueDisclosure_label_en-US" xlink:label="lab_us-gaap_CashAndCashEquivalentsFairValueDisclosure" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash and Cash Equivalents, Fair Value Disclosure</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure" xlink:to="lab_us-gaap_CashAndCashEquivalentsFairValueDisclosure" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_ce5c9217-2523-423c-b643-36b1ca44bd30_verboseLabel_en-US" xlink:label="lab_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Diluted (in shares)</link:label>
    <link:label id="lab_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_83bc79c7-5196-4ed7-ae3f-0a438111b68d_totalLabel_en-US" xlink:label="lab_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Weighted-average shares for diluted EPS (in shares)</link:label>
    <link:label id="lab_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_label_en-US" xlink:label="lab_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Weighted Average Number of Shares Outstanding, Diluted</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:to="lab_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTax_b7d9605a-db00-4f4c-82a6-045599ea924d_terseLabel_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other comprehensive income (loss), net of taxes</link:label>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTax_label_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Comprehensive Income (Loss), Net of Tax</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:to="lab_us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncomeTaxDisclosureTextBlock_6cfad808-1324-43e3-b3d3-bacaad37d2f7_verboseLabel_en-US" xlink:label="lab_us-gaap_IncomeTaxDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income taxes</link:label>
    <link:label id="lab_us-gaap_IncomeTaxDisclosureTextBlock_label_en-US" xlink:label="lab_us-gaap_IncomeTaxDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Income Tax Disclosure [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxDisclosureTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncomeTaxDisclosureTextBlock" xlink:to="lab_us-gaap_IncomeTaxDisclosureTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LongtermDebtTypeAxis_b8d91f2c-8a78-4cea-9117-0b24dc6b366b_terseLabel_en-US" xlink:label="lab_us-gaap_LongtermDebtTypeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term Debt, Type [Axis]</link:label>
    <link:label id="lab_us-gaap_LongtermDebtTypeAxis_label_en-US" xlink:label="lab_us-gaap_LongtermDebtTypeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Long-term Debt, Type [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LongtermDebtTypeAxis" xlink:to="lab_us-gaap_LongtermDebtTypeAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_NeumoraTherapeuticsIncMember_8090ea74-bee2-459e-88ee-4cd88cc38637_terseLabel_en-US" xlink:label="lab_amgn_NeumoraTherapeuticsIncMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Neumora Therapeutics, Inc. [Member]</link:label>
    <link:label id="lab_amgn_NeumoraTherapeuticsIncMember_label_en-US" xlink:label="lab_amgn_NeumoraTherapeuticsIncMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Neumora Therapeutics, Inc. [Member]</link:label>
    <link:label id="lab_amgn_NeumoraTherapeuticsIncMember_documentation_en-US" xlink:label="lab_amgn_NeumoraTherapeuticsIncMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Neumora Therapeutics, Inc.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_NeumoraTherapeuticsIncMember" xlink:href="amgn-20210930.xsd#amgn_NeumoraTherapeuticsIncMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_NeumoraTherapeuticsIncMember" xlink:to="lab_amgn_NeumoraTherapeuticsIncMember" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_CurrentFiscalYearEndDate_90194a67-e14e-4732-bcea-b78f5b2eff0b_terseLabel_en-US" xlink:label="lab_dei_CurrentFiscalYearEndDate" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current Fiscal Year End Date</link:label>
    <link:label id="lab_dei_CurrentFiscalYearEndDate_label_en-US" xlink:label="lab_dei_CurrentFiscalYearEndDate" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Current Fiscal Year End Date</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CurrentFiscalYearEndDate" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CurrentFiscalYearEndDate"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_CurrentFiscalYearEndDate" xlink:to="lab_dei_CurrentFiscalYearEndDate" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StockholdersEquityNoteDisclosureTextBlock_5aca3a5e-4ab2-4b20-a987-6ed8f3c0b1fc_verboseLabel_en-US" xlink:label="lab_us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stockholders' equity</link:label>
    <link:label id="lab_us-gaap_StockholdersEquityNoteDisclosureTextBlock_label_en-US" xlink:label="lab_us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Stockholders' Equity Note Disclosure [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:to="lab_us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_6b18a24e-d891-4cac-9bb3-80fb5ebc088d_verboseLabel_en-US" xlink:label="lab_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash&#160;flow hedges [Member]</link:label>
    <link:label id="lab_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_label_en-US" xlink:label="lab_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated Gain (Loss), Net, Cash Flow Hedge, Parent [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember" xlink:to="lab_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_TeneobioIncMember_eba68420-99d1-4f0a-94d5-1164fa2ef343_terseLabel_en-US" xlink:label="lab_amgn_TeneobioIncMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Teneobio Inc.</link:label>
    <link:label id="lab_amgn_TeneobioIncMember_label_en-US" xlink:label="lab_amgn_TeneobioIncMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Teneobio Inc. [Member]</link:label>
    <link:label id="lab_amgn_TeneobioIncMember_documentation_en-US" xlink:label="lab_amgn_TeneobioIncMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Teneobio Inc.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TeneobioIncMember" xlink:href="amgn-20210930.xsd#amgn_TeneobioIncMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TeneobioIncMember" xlink:to="lab_amgn_TeneobioIncMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_ccead560-3c56-44d3-ab15-61a4a7bf3718_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total estimated amortization of finite-lived intangible assets for 2026</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Year Five</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StatementOfCashFlowsAbstract_ca5bcd41-7b36-45ce-ad83-0eeac2dbe674_terseLabel_en-US" xlink:label="lab_us-gaap_StatementOfCashFlowsAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Cash Flows [Abstract]</link:label>
    <link:label id="lab_us-gaap_StatementOfCashFlowsAbstract_label_en-US" xlink:label="lab_us-gaap_StatementOfCashFlowsAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement of Cash Flows [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract" xlink:to="lab_us-gaap_StatementOfCashFlowsAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PaymentsToAcquireEquityMethodInvestments_f7a734d3-a8ad-402a-a506-497b3e10d07d_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_PaymentsToAcquireEquityMethodInvestments" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Purchases of equity method investments</link:label>
    <link:label id="lab_us-gaap_PaymentsToAcquireEquityMethodInvestments_b572a9cf-31c2-4ea2-bd82-f1779326f9c2_terseLabel_en-US" xlink:label="lab_us-gaap_PaymentsToAcquireEquityMethodInvestments" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Payments to Acquire Equity Method Investments</link:label>
    <link:label id="lab_us-gaap_PaymentsToAcquireEquityMethodInvestments_label_en-US" xlink:label="lab_us-gaap_PaymentsToAcquireEquityMethodInvestments" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Payments to Acquire Equity Method Investments</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireEquityMethodInvestments" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireEquityMethodInvestments"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PaymentsToAcquireEquityMethodInvestments" xlink:to="lab_us-gaap_PaymentsToAcquireEquityMethodInvestments" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ClassOfStockLineItems_d8a4fae0-92ba-47f9-9091-39615cc71986_terseLabel_en-US" xlink:label="lab_us-gaap_ClassOfStockLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Class of Stock [Line Items]</link:label>
    <link:label id="lab_us-gaap_ClassOfStockLineItems_label_en-US" xlink:label="lab_us-gaap_ClassOfStockLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Class of Stock [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ClassOfStockLineItems" xlink:to="lab_us-gaap_ClassOfStockLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NondesignatedMember_803bbbf1-c410-49f3-9574-0d1d592a6fe0_terseLabel_en-US" xlink:label="lab_us-gaap_NondesignatedMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivatives not designated as hedging instrument [Member]</link:label>
    <link:label id="lab_us-gaap_NondesignatedMember_label_en-US" xlink:label="lab_us-gaap_NondesignatedMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Not Designated as Hedging Instrument [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NondesignatedMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NondesignatedMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NondesignatedMember" xlink:to="lab_us-gaap_NondesignatedMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_146798cd-425a-41b1-9823-d2185259e5c1_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Assets, Major Class Name [Domain]</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Assets, Major Class Name [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_4db227c4-2274-40c6-b95e-39d046a80ece_terseLabel_en-US" xlink:label="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Indefinite-lived Intangible Assets [Line Items]</link:label>
    <link:label id="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_label_en-US" xlink:label="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Indefinite-lived Intangible Assets [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems" xlink:to="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue_d09776cb-3c8b-4a3e-8be3-2e5d065fd1cc_terseLabel_en-US" xlink:label="lab_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturing after three years through five years</link:label>
    <link:label id="lab_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue_label_en-US" xlink:label="lab_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Available-For-Sale Securities, Debt Maturities, After Three Through Five Years, Fair Value</link:label>
    <link:label id="lab_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue_documentation_en-US" xlink:label="lab_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Available-For-Sale Securities, Debt Maturities, After Three Through Five Years, Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue" xlink:href="amgn-20210930.xsd#amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue" xlink:to="lab_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInInvestingActivities_398b5a4e-d90e-429d-8d1d-c2818ee6d606_totalLabel_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net cash provided by (used in) investing activities</link:label>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInInvestingActivities_label_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Cash Provided by (Used in) Investing Activities</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:to="lab_us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_d3fd04c7-7496-4455-a196-97dfd28d90a0_verboseLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Changes in operating assets and liabilities, net of acquisitions:</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Increase (Decrease) in Operating Capital [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:to="lab_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_c3303239-b623-4a3c-9297-e268b32bed1e_verboseLabel_en-US" xlink:label="lab_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated depreciation and amortization on property, plant and equipment</link:label>
    <link:label id="lab_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_label_en-US" xlink:label="lab_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:to="lab_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_38147ea6-c9bf-4e77-9e38-9777d818f141_terseLabel_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">(Losses) gains on available-for-sale securities</link:label>
    <link:label id="lab_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_label_en-US" xlink:label="lab_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Comprehensive Income (Loss), Available-for-sale Securities Adjustment, Net of Tax, Portion Attributable to Parent</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent" xlink:to="lab_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_7a01eaca-4702-4077-ade5-b2eecf986c87_verboseLabel_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash flows from operating activities:</link:label>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_label_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Cash Provided by (Used in) Operating Activities [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:to="lab_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ConsolidationPolicyTextBlock_71d2330d-1ef1-482e-80f2-9c6526428393_verboseLabel_en-US" xlink:label="lab_us-gaap_ConsolidationPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Principles of consolidation</link:label>
    <link:label id="lab_us-gaap_ConsolidationPolicyTextBlock_label_en-US" xlink:label="lab_us-gaap_ConsolidationPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Consolidation, Policy [Policy Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConsolidationPolicyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConsolidationPolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ConsolidationPolicyTextBlock" xlink:to="lab_us-gaap_ConsolidationPolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LiabilitiesCurrent_5b4ed45d-b624-4266-b1e1-00407b9344a2_totalLabel_en-US" xlink:label="lab_us-gaap_LiabilitiesCurrent" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total current liabilities</link:label>
    <link:label id="lab_us-gaap_LiabilitiesCurrent_label_en-US" xlink:label="lab_us-gaap_LiabilitiesCurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Liabilities, Current</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LiabilitiesCurrent" xlink:to="lab_us-gaap_LiabilitiesCurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1_83baaf25-ae48-49cf-beb0-e00e2e069283_terseLabel_en-US" xlink:label="lab_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Gains (losses) on fair value hedging relationships, Hedged items</link:label>
    <link:label id="lab_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1_label_en-US" xlink:label="lab_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Change in Unrealized Gain (Loss) on Hedged Item in Fair Value Hedge</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1" xlink:to="lab_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ClassOfStockDomain_215dd778-8b4a-46d3-8d16-bb3404a733f2_terseLabel_en-US" xlink:label="lab_us-gaap_ClassOfStockDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Class of Stock [Domain]</link:label>
    <link:label id="lab_us-gaap_ClassOfStockDomain_label_en-US" xlink:label="lab_us-gaap_ClassOfStockDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Class of Stock [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfStockDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ClassOfStockDomain" xlink:to="lab_us-gaap_ClassOfStockDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_PaymentsToAcquireBusinessesGross_9ddeb6ee-55bc-440e-83d0-c4f1ceb7137e_terseLabel_en-US" xlink:label="lab_us-gaap_PaymentsToAcquireBusinessesGross" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cash paid</link:label>
    <link:label id="lab_us-gaap_PaymentsToAcquireBusinessesGross_label_en-US" xlink:label="lab_us-gaap_PaymentsToAcquireBusinessesGross" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Payments to Acquire Businesses, Gross</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesGross" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesGross"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PaymentsToAcquireBusinessesGross" xlink:to="lab_us-gaap_PaymentsToAcquireBusinessesGross" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_OtherShortTermInterestBearingSecuritiesMember_a17679ee-f3df-47fe-acef-dc00adce3a2b_verboseLabel_en-US" xlink:label="lab_amgn_OtherShortTermInterestBearingSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other short-term interest-bearing securities [Member]</link:label>
    <link:label id="lab_amgn_OtherShortTermInterestBearingSecuritiesMember_label_en-US" xlink:label="lab_amgn_OtherShortTermInterestBearingSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Short Term Interest Bearing Securities [Member]</link:label>
    <link:label id="lab_amgn_OtherShortTermInterestBearingSecuritiesMember_documentation_en-US" xlink:label="lab_amgn_OtherShortTermInterestBearingSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other short-term interest bearing securities.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherShortTermInterestBearingSecuritiesMember" xlink:href="amgn-20210930.xsd#amgn_OtherShortTermInterestBearingSecuritiesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OtherShortTermInterestBearingSecuritiesMember" xlink:to="lab_amgn_OtherShortTermInterestBearingSecuritiesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_HospiraMember_160832ff-b679-48f5-9dae-f81a1979640e_terseLabel_en-US" xlink:label="lab_amgn_HospiraMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hospira, Inc. [Member]</link:label>
    <link:label id="lab_amgn_HospiraMember_label_en-US" xlink:label="lab_amgn_HospiraMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hospira [Member]</link:label>
    <link:label id="lab_amgn_HospiraMember_documentation_en-US" xlink:label="lab_amgn_HospiraMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Hospira [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_HospiraMember" xlink:href="amgn-20210930.xsd#amgn_HospiraMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_HospiraMember" xlink:to="lab_amgn_HospiraMember" xlink:type="arc" order="1"/>
    <link:label id="lab_currency_EUR_a9e79893-b31f-4ca7-bb78-641d740b0b34_terseLabel_en-US" xlink:label="lab_currency_EUR" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Euro Member Countries, Euro</link:label>
    <link:label id="lab_currency_EUR_label_en-US" xlink:label="lab_currency_EUR" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Euro Member Countries, Euro</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_currency_EUR" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_EUR"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_currency_EUR" xlink:to="lab_currency_EUR" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ThreePointOneFivePercentNotesDue2040Member_faa6a337-1231-42a8-a488-1bfd7ce21256_terseLabel_en-US" xlink:label="lab_amgn_ThreePointOneFivePercentNotesDue2040Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">3.15% notes due 2040 (3.15% 2040 Notes) [Member]</link:label>
    <link:label id="lab_amgn_ThreePointOneFivePercentNotesDue2040Member_label_en-US" xlink:label="lab_amgn_ThreePointOneFivePercentNotesDue2040Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point One Five Percent Notes Due 2040 [Member]</link:label>
    <link:label id="lab_amgn_ThreePointOneFivePercentNotesDue2040Member_documentation_en-US" xlink:label="lab_amgn_ThreePointOneFivePercentNotesDue2040Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point One Five Percent Notes Due 2040 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointOneFivePercentNotesDue2040Member" xlink:href="amgn-20210930.xsd#amgn_ThreePointOneFivePercentNotesDue2040Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ThreePointOneFivePercentNotesDue2040Member" xlink:to="lab_amgn_ThreePointOneFivePercentNotesDue2040Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_a994f7fc-be2f-42ad-b267-f1b71046633c_terseLabel_en-US" xlink:label="lab_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification out of Accumulated Other Comprehensive Income [Line Items]</link:label>
    <link:label id="lab_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_label_en-US" xlink:label="lab_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification Adjustment out of Accumulated Other Comprehensive Income [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems" xlink:to="lab_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_57267193-7603-41ba-b05a-b3945de9cdb4_terseLabel_en-US" xlink:label="lab_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">1.85% notes due 2021 (1.85% 2021 Notes) [Member]</link:label>
    <link:label id="lab_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_label_en-US" xlink:label="lab_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">One Point Eight Five Percent Notes Due Two Zero Two One [Member]</link:label>
    <link:label id="lab_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_documentation_en-US" xlink:label="lab_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">One Point Eight Five Percent Notes Due Two Zero Two One [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember" xlink:href="amgn-20210930.xsd#amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember" xlink:to="lab_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_GoodwillForeignCurrencyTranslationGainLoss_5d861e27-a094-4924-91b4-7c4ae08a61e9_terseLabel_en-US" xlink:label="lab_us-gaap_GoodwillForeignCurrencyTranslationGainLoss" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Currency translation adjustment</link:label>
    <link:label id="lab_us-gaap_GoodwillForeignCurrencyTranslationGainLoss_label_en-US" xlink:label="lab_us-gaap_GoodwillForeignCurrencyTranslationGainLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Goodwill, Foreign Currency Translation Gain (Loss)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillForeignCurrencyTranslationGainLoss" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GoodwillForeignCurrencyTranslationGainLoss"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_GoodwillForeignCurrencyTranslationGainLoss" xlink:to="lab_us-gaap_GoodwillForeignCurrencyTranslationGainLoss" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_MoneyMarketFundsMember_1e2c96e7-561d-4d6a-b609-526d78ab366c_verboseLabel_en-US" xlink:label="lab_us-gaap_MoneyMarketFundsMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Money market mutual funds [Member]</link:label>
    <link:label id="lab_us-gaap_MoneyMarketFundsMember_label_en-US" xlink:label="lab_us-gaap_MoneyMarketFundsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Money Market Funds [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MoneyMarketFundsMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MoneyMarketFundsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_MoneyMarketFundsMember" xlink:to="lab_us-gaap_MoneyMarketFundsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_LossContingenciesTable_c798c6a3-a883-42de-a2ce-082aa1a34dc3_terseLabel_en-US" xlink:label="lab_us-gaap_LossContingenciesTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingencies [Table]</link:label>
    <link:label id="lab_us-gaap_LossContingenciesTable_label_en-US" xlink:label="lab_us-gaap_LossContingenciesTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Loss Contingencies [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingenciesTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LossContingenciesTable" xlink:to="lab_us-gaap_LossContingenciesTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_d09ce29b-c7dc-43f0-974d-5a89f89e3473_terseLabel_en-US" xlink:label="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification out of Accumulated Other Comprehensive Income [Member]</link:label>
    <link:label id="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_label_en-US" xlink:label="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Reclassification out of Accumulated Other Comprehensive Income [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember" xlink:to="lab_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityAddressPostalZipCode_e886cb58-48ec-49d9-8a82-f17ce689cc0c_terseLabel_en-US" xlink:label="lab_dei_EntityAddressPostalZipCode" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Address, Postal Zip Code</link:label>
    <link:label id="lab_dei_EntityAddressPostalZipCode_label_en-US" xlink:label="lab_dei_EntityAddressPostalZipCode" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Entity Address, Postal Zip Code</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressPostalZipCode"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityAddressPostalZipCode" xlink:to="lab_dei_EntityAddressPostalZipCode" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_9eb9b2c5-9c5c-400d-9365-59e09e3996f3_negatedLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Unamortized bond discounts, premiums and issuance costs, net</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet" xlink:to="lab_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_9b181300-90ae-4e9a-b4af-2bba0aea8e45_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instruments, Gain (Loss) [Table]</link:label>
    <link:label id="lab_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_label_en-US" xlink:label="lab_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Instruments, Gain (Loss) [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:to="lab_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DebtInstrumentNameDomain_8947998d-d45b-4d9b-91d9-c49930a618a3_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentNameDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument, Name [Domain]</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentNameDomain_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentNameDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Instrument, Name [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentNameDomain" xlink:to="lab_us-gaap_DebtInstrumentNameDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_Security12bTitle_27f16298-04dd-4d42-bd02-94738536bfdd_terseLabel_en-US" xlink:label="lab_dei_Security12bTitle" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Title of 12(b) Security</link:label>
    <link:label id="lab_dei_Security12bTitle_label_en-US" xlink:label="lab_dei_Security12bTitle" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Title of 12(b) Security</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_Security12bTitle"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_Security12bTitle" xlink:to="lab_dei_Security12bTitle" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_OtherAssetsCurrent_3f363706-85b9-4503-9621-a25e4d948d71_verboseLabel_en-US" xlink:label="lab_us-gaap_OtherAssetsCurrent" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other current assets</link:label>
    <link:label id="lab_us-gaap_OtherAssetsCurrent_label_en-US" xlink:label="lab_us-gaap_OtherAssetsCurrent" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other Assets, Current</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsCurrent" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherAssetsCurrent"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherAssetsCurrent" xlink:to="lab_us-gaap_OtherAssetsCurrent" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_StatementTable_b173f7ca-0a19-49a6-bef3-d44612a8364c_terseLabel_en-US" xlink:label="lab_us-gaap_StatementTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement [Table]</link:label>
    <link:label id="lab_us-gaap_StatementTable_label_en-US" xlink:label="lab_us-gaap_StatementTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statement [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StatementTable" xlink:to="lab_us-gaap_StatementTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_52179d8e-ccbf-4eb9-b392-0b57497399d3_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Collaborative Arrangement and Arrangement Other than Collaborative [Table]</link:label>
    <link:label id="lab_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_label_en-US" xlink:label="lab_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Collaborative Arrangement and Arrangement Other than Collaborative [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable" xlink:to="lab_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AssetBackedSecuritiesMember_a03b8aae-8223-46c5-8d68-eed3a5dd4dcf_terseLabel_en-US" xlink:label="lab_us-gaap_AssetBackedSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other mortgage- and asset-backed securities [Member]</link:label>
    <link:label id="lab_us-gaap_AssetBackedSecuritiesMember_label_en-US" xlink:label="lab_us-gaap_AssetBackedSecuritiesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Asset-backed Securities [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetBackedSecuritiesMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetBackedSecuritiesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AssetBackedSecuritiesMember" xlink:to="lab_us-gaap_AssetBackedSecuritiesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_af19730d-5e0e-4235-82c2-9bbb95ddfd2b_terseLabel_en-US" xlink:label="lab_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other recent accounting pronouncements</link:label>
    <link:label id="lab_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_label_en-US" xlink:label="lab_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">New Accounting Pronouncements, Policy [Policy Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:to="lab_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember_524b5f24-5d5d-4bfe-8bf5-a5c53d94a19a_verboseLabel_en-US" xlink:label="lab_amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued liabilities/Other noncurrent liabilities [Member]</link:label>
    <link:label id="lab_amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember_label_en-US" xlink:label="lab_amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued Liabilities Other Non Current Liabilities [Member]</link:label>
    <link:label id="lab_amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember_documentation_en-US" xlink:label="lab_amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Accrued liabilities/other non-current liabilities.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember" xlink:href="amgn-20210930.xsd#amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember" xlink:to="lab_amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_RangeAxis_afaec836-05cf-4ffc-a0ad-197c761b9834_terseLabel_en-US" xlink:label="lab_srt_RangeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statistical Measurement [Axis]</link:label>
    <link:label id="lab_srt_RangeAxis_label_en-US" xlink:label="lab_srt_RangeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Statistical Measurement [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_RangeAxis" xlink:to="lab_srt_RangeAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeFairValueOfDerivativeLiability_6825b985-2e80-43d3-a6b0-4fae02e31f1d_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeFairValueOfDerivativeLiability" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Total derivative liabilities, fair value</link:label>
    <link:label id="lab_us-gaap_DerivativeFairValueOfDerivativeLiability_label_en-US" xlink:label="lab_us-gaap_DerivativeFairValueOfDerivativeLiability" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative Liability, Fair Value, Gross Liability</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeLiability" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeLiability"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeFairValueOfDerivativeLiability" xlink:to="lab_us-gaap_DerivativeFairValueOfDerivativeLiability" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SubsequentEventMember_d63b8d0f-00f1-4251-ae99-b10369a89d5c_terseLabel_en-US" xlink:label="lab_us-gaap_SubsequentEventMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Subsequent Event [Member]</link:label>
    <link:label id="lab_us-gaap_SubsequentEventMember_label_en-US" xlink:label="lab_us-gaap_SubsequentEventMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Subsequent Event [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SubsequentEventMember" xlink:to="lab_us-gaap_SubsequentEventMember" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_CoverAbstract_e13a66f4-eba2-44be-8d8a-c2c3af762479_terseLabel_en-US" xlink:label="lab_dei_CoverAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cover [Abstract]</link:label>
    <link:label id="lab_dei_CoverAbstract_label_en-US" xlink:label="lab_dei_CoverAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Cover [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CoverAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_CoverAbstract" xlink:to="lab_dei_CoverAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DerivativeBasisSpreadOnVariableRate_4fe22f46-8f46-4713-b9df-c9377be2619e_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeBasisSpreadOnVariableRate" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative, Basis Spread on Variable Rate</link:label>
    <link:label id="lab_us-gaap_DerivativeBasisSpreadOnVariableRate_label_en-US" xlink:label="lab_us-gaap_DerivativeBasisSpreadOnVariableRate" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Derivative, Basis Spread on Variable Rate</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeBasisSpreadOnVariableRate" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeBasisSpreadOnVariableRate"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DerivativeBasisSpreadOnVariableRate" xlink:to="lab_us-gaap_DerivativeBasisSpreadOnVariableRate" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_16090edd-c2fa-40ec-a5bc-7ff8ffa27722_terseLabel_en-US" xlink:label="lab_amgn_ThreePointSixTwoFivePercentNotesDue2022Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">3.625% notes due 2022 (3.625% 2022 Notes) [Member]</link:label>
    <link:label id="lab_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_label_en-US" xlink:label="lab_amgn_ThreePointSixTwoFivePercentNotesDue2022Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point Six Two Five Percent Notes Due 2022 [Member]</link:label>
    <link:label id="lab_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_documentation_en-US" xlink:label="lab_amgn_ThreePointSixTwoFivePercentNotesDue2022Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Three Point Six Two Five Percent Notes Due 2022 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointSixTwoFivePercentNotesDue2022Member" xlink:href="amgn-20210930.xsd#amgn_ThreePointSixTwoFivePercentNotesDue2022Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ThreePointSixTwoFivePercentNotesDue2022Member" xlink:to="lab_amgn_ThreePointSixTwoFivePercentNotesDue2022Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsNet_a611a05c-e62b-4608-81ce-5027dec224a0_totalLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsNet" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Other intangible assets, net</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsNet_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsNet" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Finite-Lived Intangible Assets, Net</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsNet" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_Goodwill_f2c02c92-a5c8-4e2a-90b3-dae17a4af235_terseLabel_en-US" xlink:label="lab_us-gaap_Goodwill" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Goodwill</link:label>
    <link:label id="lab_us-gaap_Goodwill_af8c86cb-52a4-4bfb-b10b-7944fd67e944_periodStartLabel_en-US" xlink:label="lab_us-gaap_Goodwill" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Beginning balance</link:label>
    <link:label id="lab_us-gaap_Goodwill_a3353dda-8b68-403b-99a6-6da6d0a37058_periodEndLabel_en-US" xlink:label="lab_us-gaap_Goodwill" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Ending balance</link:label>
    <link:label id="lab_us-gaap_Goodwill_label_en-US" xlink:label="lab_us-gaap_Goodwill" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Goodwill</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Goodwill"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_Goodwill" xlink:to="lab_us-gaap_Goodwill" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_BasicAndDilutedEarningPerShareAbstract_ef4a05bd-cf39-45f7-8337-195a92f10fab_verboseLabel_en-US" xlink:label="lab_amgn_BasicAndDilutedEarningPerShareAbstract" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Computation of basic and diluted earnings per share</link:label>
    <link:label id="lab_amgn_BasicAndDilutedEarningPerShareAbstract_label_en-US" xlink:label="lab_amgn_BasicAndDilutedEarningPerShareAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Basic And Diluted Earning Per Share [Abstract]</link:label>
    <link:label id="lab_amgn_BasicAndDilutedEarningPerShareAbstract_documentation_en-US" xlink:label="lab_amgn_BasicAndDilutedEarningPerShareAbstract" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Basic and diluted earning per share.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_BasicAndDilutedEarningPerShareAbstract" xlink:href="amgn-20210930.xsd#amgn_BasicAndDilutedEarningPerShareAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_BasicAndDilutedEarningPerShareAbstract" xlink:to="lab_amgn_BasicAndDilutedEarningPerShareAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_currency_USD_c570907c-a756-45ae-b96b-a16e0a3d1cd5_terseLabel_en-US" xlink:label="lab_currency_USD" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">United States of America, Dollars</link:label>
    <link:label id="lab_currency_USD_label_en-US" xlink:label="lab_currency_USD" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">United States of America, Dollars</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_currency_USD" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_USD"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_currency_USD" xlink:to="lab_currency_USD" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember_0e9c1b11-4e04-48f3-8451-0af2a8edddfc_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Measured at Net Asset Value Per Share [Member]</link:label>
    <link:label id="lab_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember_label_en-US" xlink:label="lab_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair Value Measured at Net Asset Value Per Share [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember" xlink:to="lab_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ForwardContractsMember_881d5b43-483b-4ee4-9a11-8d4f67e192a5_verboseLabel_en-US" xlink:label="lab_us-gaap_ForwardContractsMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Foreign currency forward contracts [Member]</link:label>
    <link:label id="lab_us-gaap_ForwardContractsMember_label_en-US" xlink:label="lab_us-gaap_ForwardContractsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Forward Contracts [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForwardContractsMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForwardContractsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ForwardContractsMember" xlink:to="lab_us-gaap_ForwardContractsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_ScenarioUnspecifiedDomain_b59b27ba-4b04-48d4-be47-e4a84fc9e2c4_terseLabel_en-US" xlink:label="lab_srt_ScenarioUnspecifiedDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Scenario [Domain]</link:label>
    <link:label id="lab_srt_ScenarioUnspecifiedDomain_label_en-US" xlink:label="lab_srt_ScenarioUnspecifiedDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Scenario [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ScenarioUnspecifiedDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_ScenarioUnspecifiedDomain" xlink:to="lab_srt_ScenarioUnspecifiedDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfGoodwillTextBlock_3656c2d2-d414-4eb0-bf6b-93437bd54d0e_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfGoodwillTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of goodwill</link:label>
    <link:label id="lab_us-gaap_ScheduleOfGoodwillTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfGoodwillTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Goodwill [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfGoodwillTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfGoodwillTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfGoodwillTextBlock" xlink:to="lab_us-gaap_ScheduleOfGoodwillTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SubsequentEventTypeAxis_a18358b5-49ae-4972-9c3f-b7c2016fe04f_terseLabel_en-US" xlink:label="lab_us-gaap_SubsequentEventTypeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Subsequent Event Type [Axis]</link:label>
    <link:label id="lab_us-gaap_SubsequentEventTypeAxis_label_en-US" xlink:label="lab_us-gaap_SubsequentEventTypeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Subsequent Event Type [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SubsequentEventTypeAxis" xlink:to="lab_us-gaap_SubsequentEventTypeAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock_79c6a170-a999-412a-8575-2fa633cac118_verboseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Fair values of derivatives included in the Condensed Consolidated Balance Sheets</link:label>
    <link:label id="lab_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock_label_en-US" xlink:label="lab_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Derivative Instruments in Statement of Financial Position, Fair Value [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock" xlink:to="lab_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DevelopedTechnologyRightsMember_1285b397-743e-4631-b050-519479f2b114_verboseLabel_en-US" xlink:label="lab_us-gaap_DevelopedTechnologyRightsMember" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Developed-Product-Technology Rights [Member]</link:label>
    <link:label id="lab_us-gaap_DevelopedTechnologyRightsMember_label_en-US" xlink:label="lab_us-gaap_DevelopedTechnologyRightsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Developed Technology Rights [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DevelopedTechnologyRightsMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DevelopedTechnologyRightsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DevelopedTechnologyRightsMember" xlink:to="lab_us-gaap_DevelopedTechnologyRightsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_f18dbe2c-2bb1-454d-9281-98c4e6de14de_terseLabel_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturing in one year or less</link:label>
    <link:label id="lab_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_label_en-US" xlink:label="lab_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue" xlink:to="lab_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_ForeignCurrencyAndCrossCurrencySwapsMember_7ef569a6-c965-4202-b5fc-d456e1428218_terseLabel_en-US" xlink:label="lab_amgn_ForeignCurrencyAndCrossCurrencySwapsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Foreign currency and cross currency swap contracts [Member]</link:label>
    <link:label id="lab_amgn_ForeignCurrencyAndCrossCurrencySwapsMember_label_en-US" xlink:label="lab_amgn_ForeignCurrencyAndCrossCurrencySwapsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Foreign Currency and Cross Currency Swaps [Member]</link:label>
    <link:label id="lab_amgn_ForeignCurrencyAndCrossCurrencySwapsMember_documentation_en-US" xlink:label="lab_amgn_ForeignCurrencyAndCrossCurrencySwapsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Foreign currency and cross currency swaps.</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ForeignCurrencyAndCrossCurrencySwapsMember" xlink:href="amgn-20210930.xsd#amgn_ForeignCurrencyAndCrossCurrencySwapsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ForeignCurrencyAndCrossCurrencySwapsMember" xlink:to="lab_amgn_ForeignCurrencyAndCrossCurrencySwapsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_d803afc3-e4db-4ed0-930f-5380c779936c_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Investment Income [Line Items]</link:label>
    <link:label id="lab_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_label_en-US" xlink:label="lab_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Net Investment Income [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems" xlink:to="lab_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_d43e3601-2907-4901-8559-a9bcb127bfbe_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Finite-Lived Intangible Assets [Table]</link:label>
    <link:label id="lab_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_label_en-US" xlink:label="lab_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Schedule of Finite-Lived Intangible Assets [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable" xlink:to="lab_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_1d040252-3184-451e-b258-db07b88a9d85_terseLabel_en-US" xlink:label="lab_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]</link:label>
    <link:label id="lab_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_label_en-US" xlink:label="lab_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems" xlink:to="lab_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember_94735615-2113-445e-8a63-a4d57df22160_terseLabel_en-US" xlink:label="lab_us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common stock and additional paid-in capital [Member]</link:label>
    <link:label id="lab_us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember_label_en-US" xlink:label="lab_us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Common Stock Including Additional Paid in Capital [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember" xlink:to="lab_us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember" xlink:type="arc" order="1"/>
    <link:label id="lab_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue_46b73507-311a-4ffd-818d-d1cd29b68838_terseLabel_en-US" xlink:label="lab_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Maturing after one year through three years</link:label>
    <link:label id="lab_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue_label_en-US" xlink:label="lab_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Available-For Sale Securities, Debt Maturities, After One Through Three Years, Fair Value</link:label>
    <link:label id="lab_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue_documentation_en-US" xlink:label="lab_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xmlns:xml="http://www.w3.org/XML/1998/namespace" xml:lang="en-US">Available-For Sale Securities, Debt Maturities, After One Through Three Years, Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue" xlink:href="amgn-20210930.xsd#amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue" xlink:to="lab_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue" xlink:type="arc" order="1"/>
  </link:labelLink>
</link:linkbase>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.PRE
<SEQUENCE>9
<FILENAME>amgn-20210930_pre.xml
<DESCRIPTION>XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE DOCUMENT
<TEXT>
<XBRL>
<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2021 Workiva-->
<!--r:e5235af6-2e2c-44cc-b741-bc0b6d42fa8f,g:5c86b37c-c57f-4c71-acc2-468d6efa37c1-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.amgen.com/role/CoverPage" xlink:type="simple" xlink:href="amgn-20210930.xsd#CoverPage"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/CoverPage" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_218997a6-e671-4ca4-b06c-709c2e1793f3" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntitiesTable_01b57b85-be53-43d0-975c-30963e42dd18" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntitiesTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_218997a6-e671-4ca4-b06c-709c2e1793f3" xlink:to="loc_dei_EntitiesTable_01b57b85-be53-43d0-975c-30963e42dd18" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityListingsExchangeAxis_d1c213f4-9da7-4285-8718-54c9983da559" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityListingsExchangeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntitiesTable_01b57b85-be53-43d0-975c-30963e42dd18" xlink:to="loc_dei_EntityListingsExchangeAxis_d1c213f4-9da7-4285-8718-54c9983da559" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_ExchangeDomain_256f6c3f-dbe1-4db2-add8-e76890adaf7b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_ExchangeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsExchangeAxis_d1c213f4-9da7-4285-8718-54c9983da559" xlink:to="loc_dei_ExchangeDomain_256f6c3f-dbe1-4db2-add8-e76890adaf7b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_exch_XNGS_413afd56-e23a-469d-82c1-c9a5303a7998" xlink:href="https://xbrl.sec.gov/exch/2021/exch-2021.xsd#exch_XNGS"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_ExchangeDomain_256f6c3f-dbe1-4db2-add8-e76890adaf7b" xlink:to="loc_exch_XNGS_413afd56-e23a-469d-82c1-c9a5303a7998" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_2661aba9-85d4-4d0f-9ac1-04dc6daf1fc5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntitiesTable_01b57b85-be53-43d0-975c-30963e42dd18" xlink:to="loc_us-gaap_StatementClassOfStockAxis_2661aba9-85d4-4d0f-9ac1-04dc6daf1fc5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_fd4c96f4-deb0-483b-a1a1-8d0c12c50571" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfStockDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_2661aba9-85d4-4d0f-9ac1-04dc6daf1fc5" xlink:to="loc_us-gaap_ClassOfStockDomain_fd4c96f4-deb0-483b-a1a1-8d0c12c50571" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_6e491290-cf54-4f63-8ac6-3eebcdb3efb8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_fd4c96f4-deb0-483b-a1a1-8d0c12c50571" xlink:to="loc_us-gaap_CommonStockMember_6e491290-cf54-4f63-8ac6-3eebcdb3efb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_A1.250SeniorNotesDue2022Member_358d3b33-f5fc-40cf-8078-6b3815eabfb8" xlink:href="amgn-20210930.xsd#amgn_A1.250SeniorNotesDue2022Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_fd4c96f4-deb0-483b-a1a1-8d0c12c50571" xlink:to="loc_amgn_A1.250SeniorNotesDue2022Member_358d3b33-f5fc-40cf-8078-6b3815eabfb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_A2.00SeniorNotesDue2026Member_843ade05-721b-4a72-8822-e0660c02f527" xlink:href="amgn-20210930.xsd#amgn_A2.00SeniorNotesDue2026Member"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_fd4c96f4-deb0-483b-a1a1-8d0c12c50571" xlink:to="loc_amgn_A2.00SeniorNotesDue2026Member_843ade05-721b-4a72-8822-e0660c02f527" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityInformationLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntitiesTable_01b57b85-be53-43d0-975c-30963e42dd18" xlink:to="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_d2b7d437-af72-4593-9a03-e3b1b89d68c6" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_DocumentType_d2b7d437-af72-4593-9a03-e3b1b89d68c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentQuarterlyReport_4fee6c6a-4076-437c-beed-27a9d33c2d5d" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentQuarterlyReport"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_DocumentQuarterlyReport_4fee6c6a-4076-437c-beed-27a9d33c2d5d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_bd278e5b-1973-45cc-a2c9-aa53746f98cf" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_DocumentPeriodEndDate_bd278e5b-1973-45cc-a2c9-aa53746f98cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentTransitionReport_b679502b-098d-4c5f-80b5-262623c93d92" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentTransitionReport"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_DocumentTransitionReport_b679502b-098d-4c5f-80b5-262623c93d92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_2ca92a42-6d56-4f29-9c7b-e924a575eeb2" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityFileNumber_2ca92a42-6d56-4f29-9c7b-e924a575eeb2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_0a799626-c61f-45b8-8f2c-d27c711feffd" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityRegistrantName_0a799626-c61f-45b8-8f2c-d27c711feffd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_ff06d7ef-7303-4fe7-b8aa-fe1aba6410c0" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityCentralIndexKey_ff06d7ef-7303-4fe7-b8aa-fe1aba6410c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_eca216e4-fb32-48ce-b140-96c472870c27" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_AmendmentFlag_eca216e4-fb32-48ce-b140-96c472870c27" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalYearFocus_b9373172-93cd-4023-abfe-15c063f3750b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentFiscalYearFocus"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_DocumentFiscalYearFocus_b9373172-93cd-4023-abfe-15c063f3750b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalPeriodFocus_a6e44e17-b981-49b8-a181-48211da9e5e1" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentFiscalPeriodFocus"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_DocumentFiscalPeriodFocus_a6e44e17-b981-49b8-a181-48211da9e5e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CurrentFiscalYearEndDate_74833464-c03e-4081-8abb-9d3aba7c441f" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CurrentFiscalYearEndDate"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_CurrentFiscalYearEndDate_74833464-c03e-4081-8abb-9d3aba7c441f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_38672f86-f5c4-408b-a483-4538206f6266" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityIncorporationStateCountryCode_38672f86-f5c4-408b-a483-4538206f6266" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_a63b595c-91bf-4c23-b237-5a0c78211aab" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityTaxIdentificationNumber_a63b595c-91bf-4c23-b237-5a0c78211aab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_36cd7e63-3c05-4c2b-a04d-6802f3eacc6b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityAddressAddressLine1_36cd7e63-3c05-4c2b-a04d-6802f3eacc6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_1f5608b0-3b93-4e9e-999d-105e3c20322c" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityAddressCityOrTown_1f5608b0-3b93-4e9e-999d-105e3c20322c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_6c88e06a-45a0-49da-a6b3-8264644bc58b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityAddressStateOrProvince_6c88e06a-45a0-49da-a6b3-8264644bc58b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_fae8f267-b2e7-4b6c-a1ce-6718e8ba488a" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityAddressPostalZipCode_fae8f267-b2e7-4b6c-a1ce-6718e8ba488a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_147e05b0-b86b-498e-945c-92f837ee4dee" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_CityAreaCode_147e05b0-b86b-498e-945c-92f837ee4dee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_d28dd0c9-fd7c-4791-a5ec-176025eb7516" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_LocalPhoneNumber_d28dd0c9-fd7c-4791-a5ec-176025eb7516" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_2e921c9f-7da3-459a-ada0-353cfc4a3a85" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_Security12bTitle_2e921c9f-7da3-459a-ada0-353cfc4a3a85" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_7dd4d5c4-455b-417a-87bd-b0034b48fd7c" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_TradingSymbol_7dd4d5c4-455b-417a-87bd-b0034b48fd7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_357c417e-0ef4-4bcc-8b02-e26b97e787de" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_SecurityExchangeName_357c417e-0ef4-4bcc-8b02-e26b97e787de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCurrentReportingStatus_cf011862-01d1-4e5c-9b10-ea03a54e9641" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCurrentReportingStatus"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityCurrentReportingStatus_cf011862-01d1-4e5c-9b10-ea03a54e9641" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInteractiveDataCurrent_14d33b15-38a6-4812-b355-911d79444830" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityInteractiveDataCurrent"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityInteractiveDataCurrent_14d33b15-38a6-4812-b355-911d79444830" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFilerCategory_63bfbf25-f81b-4a4f-9154-9a45d0ca41c1" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityFilerCategory"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityFilerCategory_63bfbf25-f81b-4a4f-9154-9a45d0ca41c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntitySmallBusiness_d836a9ed-0878-4377-8675-61a0183d40bb" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntitySmallBusiness"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntitySmallBusiness_d836a9ed-0878-4377-8675-61a0183d40bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_c0b137f5-d92a-486a-bebe-50c26ff5f80b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityEmergingGrowthCompany_c0b137f5-d92a-486a-bebe-50c26ff5f80b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityShellCompany_1b578911-d757-454e-977b-e7c58cf8cb0e" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityShellCompany"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityShellCompany_1b578911-d757-454e-977b-e7c58cf8cb0e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_fc252067-055b-4b22-90f0-bbfa79e8843f" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCommonStockSharesOutstanding"/>
    <link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityInformationLineItems_79324acf-4f7f-426b-8166-1174ee26de67" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_fc252067-055b-4b22-90f0-bbfa79e8843f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome" xlink:type="simple" xlink:href="amgn-20210930.xsd#CondensedConsolidatedStatementsofComprehensiveIncome"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_19a17d30-e479-49b0-aad6-24c955593c30" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_34f39faa-86da-467b-9bb7-1197e2940b10" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_19a17d30-e479-49b0-aad6-24c955593c30" xlink:to="loc_us-gaap_NetIncomeLoss_34f39faa-86da-467b-9bb7-1197e2940b10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract_6ecfdc07-bf03-4171-a3e1-32c8e4de73f7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_19a17d30-e479-49b0-aad6-24c955593c30" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract_6ecfdc07-bf03-4171-a3e1-32c8e4de73f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_531fa054-8352-4826-afde-13190f6f2b6a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract_6ecfdc07-bf03-4171-a3e1-32c8e4de73f7" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_531fa054-8352-4826-afde-13190f6f2b6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_0f60a8a6-75e0-4b0c-99ab-33ef4c93ac0c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract_6ecfdc07-bf03-4171-a3e1-32c8e4de73f7" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_0f60a8a6-75e0-4b0c-99ab-33ef4c93ac0c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_b1b781d9-59bb-4ce0-a3af-c450a76d6483" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract_6ecfdc07-bf03-4171-a3e1-32c8e4de73f7" xlink:to="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_b1b781d9-59bb-4ce0-a3af-c450a76d6483" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent_2f977176-2d4b-4ff5-9837-d6899e59ef55" xlink:href="amgn-20210930.xsd#amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract_6ecfdc07-bf03-4171-a3e1-32c8e4de73f7" xlink:to="loc_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent_2f977176-2d4b-4ff5-9837-d6899e59ef55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_71ad91ba-5bbf-489a-a63a-1fdb0ddfc1b9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract_6ecfdc07-bf03-4171-a3e1-32c8e4de73f7" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_71ad91ba-5bbf-489a-a63a-1fdb0ddfc1b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_97627613-83b3-4d95-aae7-47759d0741b1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_19a17d30-e479-49b0-aad6-24c955593c30" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_97627613-83b3-4d95-aae7-47759d0741b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome" xlink:type="simple" xlink:href="amgn-20210930.xsd#CondensedConsolidatedStatementsofIncome"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementAbstract_875fa8a6-ca00-4057-aef3-153e219a7ec6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_b2bffd96-2f75-4386-a786-fb5fd3508977" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_875fa8a6-ca00-4057-aef3-153e219a7ec6" xlink:to="loc_us-gaap_StatementTable_b2bffd96-2f75-4386-a786-fb5fd3508977" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_5d2336af-11bb-4f80-96d5-ce6cd02c97c4" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_b2bffd96-2f75-4386-a786-fb5fd3508977" xlink:to="loc_srt_ProductOrServiceAxis_5d2336af-11bb-4f80-96d5-ce6cd02c97c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_24c59671-596b-47a3-b917-a354cd837113" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_5d2336af-11bb-4f80-96d5-ce6cd02c97c4" xlink:to="loc_srt_ProductsAndServicesDomain_24c59671-596b-47a3-b917-a354cd837113" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_e3e889f1-ecd3-4059-acbd-4e19ad6f039d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_24c59671-596b-47a3-b917-a354cd837113" xlink:to="loc_us-gaap_ProductMember_e3e889f1-ecd3-4059-acbd-4e19ad6f039d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductAndServiceOtherMember_feded7b8-df39-487a-bebc-ff0b8396f1ab" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductAndServiceOtherMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_24c59671-596b-47a3-b917-a354cd837113" xlink:to="loc_us-gaap_ProductAndServiceOtherMember_feded7b8-df39-487a-bebc-ff0b8396f1ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_b2bffd96-2f75-4386-a786-fb5fd3508977" xlink:to="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenuesAbstract_3a19ba09-1350-4960-b8a8-fe897be03157" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenuesAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_RevenuesAbstract_3a19ba09-1350-4960-b8a8-fe897be03157" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_09614b7d-3865-4a28-a33f-c5d9c7669e8d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenuesAbstract_3a19ba09-1350-4960-b8a8-fe897be03157" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_09614b7d-3865-4a28-a33f-c5d9c7669e8d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostsAndExpensesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_15ee6ec4-0517-40fd-978e-aad6e0506b65" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_15ee6ec4-0517-40fd-978e-aad6e0506b65" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost_341563d2-0b0a-4635-b41b-c1f6c6898d41" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost_341563d2-0b0a-4635-b41b-c1f6c6898d41" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_80886054-d94a-4bb0-88a2-1541658c9de4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:to="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_80886054-d94a-4bb0-88a2-1541658c9de4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_e6e9f977-73cf-43f7-9ac2-48d4a5a88e7a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_e6e9f977-73cf-43f7-9ac2-48d4a5a88e7a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherGeneralExpense_a8888703-036c-474f-8384-68903ef92599" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherGeneralExpense"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:to="loc_us-gaap_OtherGeneralExpense_a8888703-036c-474f-8384-68903ef92599" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses_e10bfffc-4ea6-453f-8feb-611e8d609fa1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostsAndExpenses"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_6ec3d016-a37e-463d-823f-a2fbb4f9b89d" xlink:to="loc_us-gaap_CostsAndExpenses_e10bfffc-4ea6-453f-8feb-611e8d609fa1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_ff02d73b-79fa-4754-bcc0-515d23e118ec" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_OperatingIncomeLoss_ff02d73b-79fa-4754-bcc0-515d23e118ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebt_85770760-d55d-4a99-bb3d-33a224bcfcdb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestExpenseDebt"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_InterestExpenseDebt_85770760-d55d-4a99-bb3d-33a224bcfcdb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_5eb92c64-97a2-48f5-a761-f16df3afe102" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NonoperatingIncomeExpense"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_5eb92c64-97a2-48f5-a761-f16df3afe102" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_ac55f0b9-10fa-41e1-8d63-a01d85b1d529" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_ac55f0b9-10fa-41e1-8d63-a01d85b1d529" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_3b47bf84-a8d8-4b5d-8cdc-8d77b2c8b323" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_3b47bf84-a8d8-4b5d-8cdc-8d77b2c8b323" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_b9a6eb70-7c94-44e8-a09e-43c6eccbacfd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_NetIncomeLoss_b9a6eb70-7c94-44e8-a09e-43c6eccbacfd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_72e69f9d-cb40-4fae-a26f-43e040553bf9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_EarningsPerShareAbstract_72e69f9d-cb40-4fae-a26f-43e040553bf9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_9225ee63-dc9d-4611-8efe-ff108fa1b3b5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareBasic"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_72e69f9d-cb40-4fae-a26f-43e040553bf9" xlink:to="loc_us-gaap_EarningsPerShareBasic_9225ee63-dc9d-4611-8efe-ff108fa1b3b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_4059413e-4cfd-4973-92ea-17778cf5989e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareDiluted"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_72e69f9d-cb40-4fae-a26f-43e040553bf9" xlink:to="loc_us-gaap_EarningsPerShareDiluted_4059413e-4cfd-4973-92ea-17778cf5989e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_de7f44b4-6475-4ad1-872d-1b53fade021a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_b8149d8a-1002-429f-bc84-45bf128a6c2d" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_de7f44b4-6475-4ad1-872d-1b53fade021a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_6af2a997-de41-401d-b068-b67e574d8e97" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_de7f44b4-6475-4ad1-872d-1b53fade021a" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_6af2a997-de41-401d-b068-b67e574d8e97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_af7ab5aa-7367-4262-a05b-85e1f6ca23df" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_de7f44b4-6475-4ad1-872d-1b53fade021a" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_af7ab5aa-7367-4262-a05b-85e1f6ca23df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/CondensedConsolidatedBalanceSheets" xlink:type="simple" xlink:href="amgn-20210930.xsd#CondensedConsolidatedBalanceSheets"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/CondensedConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_eed7b3e8-0091-4cb7-9fbc-9e1ea2ef514b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsAbstract_2798ac91-cc41-4373-bf53-ab051873e99c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_eed7b3e8-0091-4cb7-9fbc-9e1ea2ef514b" xlink:to="loc_us-gaap_AssetsAbstract_2798ac91-cc41-4373-bf53-ab051873e99c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrentAbstract_d397655e-0fbf-47cd-8360-12b461941d2b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_2798ac91-cc41-4373-bf53-ab051873e99c" xlink:to="loc_us-gaap_AssetsCurrentAbstract_d397655e-0fbf-47cd-8360-12b461941d2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_6300135f-b2a1-4c1a-ae2e-c318e3ed35f3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_d397655e-0fbf-47cd-8360-12b461941d2b" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_6300135f-b2a1-4c1a-ae2e-c318e3ed35f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_3d5517dd-297e-4074-b0fe-e093460863ec" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_d397655e-0fbf-47cd-8360-12b461941d2b" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_3d5517dd-297e-4074-b0fe-e093460863ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_7e8596f4-2208-4d7d-8408-ef569d685a22" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_d397655e-0fbf-47cd-8360-12b461941d2b" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_7e8596f4-2208-4d7d-8408-ef569d685a22" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_7cb089e2-8c5c-413b-86ad-c60d71e8a4c1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryNet"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_d397655e-0fbf-47cd-8360-12b461941d2b" xlink:to="loc_us-gaap_InventoryNet_7cb089e2-8c5c-413b-86ad-c60d71e8a4c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsCurrent_6f2d01dd-6212-4883-95e9-4360b4a6b7fc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherAssetsCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_d397655e-0fbf-47cd-8360-12b461941d2b" xlink:to="loc_us-gaap_OtherAssetsCurrent_6f2d01dd-6212-4883-95e9-4360b4a6b7fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_39d09ca4-6762-4c81-b1aa-b9fde9ccbd88" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_d397655e-0fbf-47cd-8360-12b461941d2b" xlink:to="loc_us-gaap_AssetsCurrent_39d09ca4-6762-4c81-b1aa-b9fde9ccbd88" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_a292ee10-d0c6-4bdb-a4d2-16327e6b406d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_2798ac91-cc41-4373-bf53-ab051873e99c" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_a292ee10-d0c6-4bdb-a4d2-16327e6b406d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_66cd1443-6176-4d13-898f-326187734e59" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_2798ac91-cc41-4373-bf53-ab051873e99c" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_66cd1443-6176-4d13-898f-326187734e59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_aaff1e2b-1c18-4a87-b904-d1834a33d811" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Goodwill"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_2798ac91-cc41-4373-bf53-ab051873e99c" xlink:to="loc_us-gaap_Goodwill_aaff1e2b-1c18-4a87-b904-d1834a33d811" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_0c6a7e7b-19ab-4145-a8c5-bbe5cf9fe49f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_2798ac91-cc41-4373-bf53-ab051873e99c" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_0c6a7e7b-19ab-4145-a8c5-bbe5cf9fe49f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_c95f4a28-c76a-4d25-ab4a-fbeba6d9e1cf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Assets"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_2798ac91-cc41-4373-bf53-ab051873e99c" xlink:to="loc_us-gaap_Assets_c95f4a28-c76a-4d25-ab4a-fbeba6d9e1cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_cb110445-7973-437b-8bdb-07572178ad77" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_eed7b3e8-0091-4cb7-9fbc-9e1ea2ef514b" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_cb110445-7973-437b-8bdb-07572178ad77" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_6a4651cd-4d0a-40f7-b4f0-90dd7feea015" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_cb110445-7973-437b-8bdb-07572178ad77" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_6a4651cd-4d0a-40f7-b4f0-90dd7feea015" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_f50a2249-0025-486e-b146-252ad2092a22" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_6a4651cd-4d0a-40f7-b4f0-90dd7feea015" xlink:to="loc_us-gaap_AccountsPayableCurrent_f50a2249-0025-486e-b146-252ad2092a22" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_c69236d5-024d-4293-887b-841e575761d2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_6a4651cd-4d0a-40f7-b4f0-90dd7feea015" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_c69236d5-024d-4293-887b-841e575761d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_dda00d81-febb-4aae-b224-eb78238679d2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_6a4651cd-4d0a-40f7-b4f0-90dd7feea015" xlink:to="loc_us-gaap_LongTermDebtCurrent_dda00d81-febb-4aae-b224-eb78238679d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_f9f5079a-bbdc-4c73-825c-5d4b6aee0f5f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_6a4651cd-4d0a-40f7-b4f0-90dd7feea015" xlink:to="loc_us-gaap_LiabilitiesCurrent_f9f5079a-bbdc-4c73-825c-5d4b6aee0f5f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_785ba630-d80d-4f38-844a-32407d4f71d9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_cb110445-7973-437b-8bdb-07572178ad77" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_785ba630-d80d-4f38-844a-32407d4f71d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent_f939f2cf-970a-4d62-8de7-933d65de6c2d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilityForUncertainTaxPositionsNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_cb110445-7973-437b-8bdb-07572178ad77" xlink:to="loc_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent_f939f2cf-970a-4d62-8de7-933d65de6c2d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_13e20cb0-9f4d-4ca5-b86d-04fa7642b577" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_cb110445-7973-437b-8bdb-07572178ad77" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_13e20cb0-9f4d-4ca5-b86d-04fa7642b577" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_27a62e4d-4dc4-4ad5-b00d-d8c1aeee92d3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_cb110445-7973-437b-8bdb-07572178ad77" xlink:to="loc_us-gaap_CommitmentsAndContingencies_27a62e4d-4dc4-4ad5-b00d-d8c1aeee92d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityAbstract_49159bb0-1c0e-4ccb-bff2-c6d550c9c675" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquityAbstract"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_cb110445-7973-437b-8bdb-07572178ad77" xlink:to="loc_us-gaap_StockholdersEquityAbstract_49159bb0-1c0e-4ccb-bff2-c6d550c9c675" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStocksIncludingAdditionalPaidInCapital_ca5e36b2-e668-4f56-9622-5c480aa6f84e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStocksIncludingAdditionalPaidInCapital"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_49159bb0-1c0e-4ccb-bff2-c6d550c9c675" xlink:to="loc_us-gaap_CommonStocksIncludingAdditionalPaidInCapital_ca5e36b2-e668-4f56-9622-5c480aa6f84e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_b252b475-36ad-4f34-9bf2-5d484a92eeff" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_49159bb0-1c0e-4ccb-bff2-c6d550c9c675" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_b252b475-36ad-4f34-9bf2-5d484a92eeff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_998f2559-6060-480c-b01c-fd886a056042" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_49159bb0-1c0e-4ccb-bff2-c6d550c9c675" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_998f2559-6060-480c-b01c-fd886a056042" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_a24744c7-52a4-487e-99a9-fbc3b4d3c725" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_49159bb0-1c0e-4ccb-bff2-c6d550c9c675" xlink:to="loc_us-gaap_StockholdersEquity_a24744c7-52a4-487e-99a9-fbc3b4d3c725" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_132c59c4-9d2b-4e35-bd5a-3625dfaf74d9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_cb110445-7973-437b-8bdb-07572178ad77" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_132c59c4-9d2b-4e35-bd5a-3625dfaf74d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="simple" xlink:href="amgn-20210930.xsd#CondensedConsolidatedBalanceSheetsParenthetical"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_02dba963-3014-4c79-b7c5-c2c6f0ed977c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_56318aac-45eb-4732-8a09-14edd8bec347" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_02dba963-3014-4c79-b7c5-c2c6f0ed977c" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_56318aac-45eb-4732-8a09-14edd8bec347" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_66d55966-fca6-40a4-919f-b299c70dc061" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_02dba963-3014-4c79-b7c5-c2c6f0ed977c" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_66d55966-fca6-40a4-919f-b299c70dc061" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_c77f82d5-eefd-4b55-9296-211407c8008d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_02dba963-3014-4c79-b7c5-c2c6f0ed977c" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_c77f82d5-eefd-4b55-9296-211407c8008d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity" xlink:type="simple" xlink:href="amgn-20210930.xsd#CondensedConsolidatedStatementsofStockholdersEquity"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_3a57f376-6270-4628-a20e-5265db73d3cf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_33eac8b5-949e-4ba3-96af-c0e2c192568b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_3a57f376-6270-4628-a20e-5265db73d3cf" xlink:to="loc_us-gaap_StatementTable_33eac8b5-949e-4ba3-96af-c0e2c192568b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_5eb507c1-aa0f-4f27-b0df-466e4860d39a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_33eac8b5-949e-4ba3-96af-c0e2c192568b" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_5eb507c1-aa0f-4f27-b0df-466e4860d39a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_599f2207-121e-4a67-91af-411e6783e81f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_5eb507c1-aa0f-4f27-b0df-466e4860d39a" xlink:to="loc_us-gaap_EquityComponentDomain_599f2207-121e-4a67-91af-411e6783e81f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_5a6945df-cac4-4ad1-9749-3d66cd104a62" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_599f2207-121e-4a67-91af-411e6783e81f" xlink:to="loc_us-gaap_CommonStockMember_5a6945df-cac4-4ad1-9749-3d66cd104a62" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember_ae6946da-dc5e-42c2-90f7-13282e5bc168" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_599f2207-121e-4a67-91af-411e6783e81f" xlink:to="loc_us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember_ae6946da-dc5e-42c2-90f7-13282e5bc168" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_b17d60d5-54e6-4e6f-8276-582774d38207" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_599f2207-121e-4a67-91af-411e6783e81f" xlink:to="loc_us-gaap_RetainedEarningsMember_b17d60d5-54e6-4e6f-8276-582774d38207" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_ff0047c2-cd55-49cb-aa0f-95e9e6da8334" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_599f2207-121e-4a67-91af-411e6783e81f" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_ff0047c2-cd55-49cb-aa0f-95e9e6da8334" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_aec6d8be-38bc-40fe-9f8f-95d5a5090400" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_33eac8b5-949e-4ba3-96af-c0e2c192568b" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_aec6d8be-38bc-40fe-9f8f-95d5a5090400" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_03180f8f-adb3-40fa-9c55-2cc3b71072e7" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_aec6d8be-38bc-40fe-9f8f-95d5a5090400" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_03180f8f-adb3-40fa-9c55-2cc3b71072e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_dfe4ea6b-29ce-4512-b6ca-5e74102d04ed" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_03180f8f-adb3-40fa-9c55-2cc3b71072e7" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_dfe4ea6b-29ce-4512-b6ca-5e74102d04ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_5f94fa09-2283-41f1-a42d-0e3657288b82" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_33eac8b5-949e-4ba3-96af-c0e2c192568b" xlink:to="loc_us-gaap_StatementLineItems_5f94fa09-2283-41f1-a42d-0e3657288b82" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_5f94fa09-2283-41f1-a42d-0e3657288b82" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_ca1a7796-50c9-4813-baef-44adba643da3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_ca1a7796-50c9-4813-baef-44adba643da3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_7d0ef42e-40b2-4fe6-9406-d0c13bfa53d9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_StockholdersEquity_7d0ef42e-40b2-4fe6-9406-d0c13bfa53d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_de95967f-886f-44f3-a122-d89570687679" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_NetIncomeLoss_de95967f-886f-44f3-a122-d89570687679" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_65f2b100-ff0e-48ad-80ac-c5ff205b7ee2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_65f2b100-ff0e-48ad-80ac-c5ff205b7ee2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DividendsCommonStockCash_ecd78bc3-5f33-43e8-8eb5-e013661a7214" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DividendsCommonStockCash"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_DividendsCommonStockCash_ecd78bc3-5f33-43e8-8eb5-e013661a7214" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_93ea35ef-164b-458d-9a59-b3e6f7fd8357" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_93ea35ef-164b-458d-9a59-b3e6f7fd8357" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_7f2dd661-abc3-47b3-8381-6d5d9f42d1a4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_7f2dd661-abc3-47b3-8381-6d5d9f42d1a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_02d9c41e-ecfa-41df-b5eb-9edac59345c8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_02d9c41e-ecfa-41df-b5eb-9edac59345c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet_92478de4-37a5-440a-8503-883690b3ed14" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet_92478de4-37a5-440a-8503-883690b3ed14" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares_87cfe528-8915-4f44-9089-7ccc31a77113" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchasedAndRetiredDuringPeriodShares"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares_87cfe528-8915-4f44-9089-7ccc31a77113" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue_845a955f-f7e3-457e-8bf1-5af290c4d245" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchasedAndRetiredDuringPeriodValue"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue_845a955f-f7e3-457e-8bf1-5af290c4d245" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityOther_930e64a8-d828-458c-8d21-8901a29b9b9b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquityOther"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_StockholdersEquityOther_930e64a8-d828-458c-8d21-8901a29b9b9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_eacb84a7-ada4-4b0d-ba68-27ccefb4224e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_eacb84a7-ada4-4b0d-ba68-27ccefb4224e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_ee56688e-773f-45f7-8486-2cd7fbfb1651" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_192e0229-260d-46d8-8973-f4fefdea15c1" xlink:to="loc_us-gaap_StockholdersEquity_ee56688e-773f-45f7-8486-2cd7fbfb1651" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquityParenthetical" xlink:type="simple" xlink:href="amgn-20210930.xsd#CondensedConsolidatedStatementsofStockholdersEquityParenthetical"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquityParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_59e0f0b6-5305-4619-abd5-9d5a6345b4d0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockDividendsPerShareDeclared_be8e6e68-6059-4cc7-8517-fe5328dc78f7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockDividendsPerShareDeclared"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_59e0f0b6-5305-4619-abd5-9d5a6345b4d0" xlink:to="loc_us-gaap_CommonStockDividendsPerShareDeclared_be8e6e68-6059-4cc7-8517-fe5328dc78f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="simple" xlink:href="amgn-20210930.xsd#CondensedConsolidatedStatementsofCashFlows"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_d035736e-09c7-448f-9b1e-473ebbabf3e7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_26550966-8de3-4c94-8722-aeaf15bf6fb4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_d035736e-09c7-448f-9b1e-473ebbabf3e7" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_26550966-8de3-4c94-8722-aeaf15bf6fb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_75b32ddd-17d1-4bed-865e-e19aebe8f24b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_26550966-8de3-4c94-8722-aeaf15bf6fb4" xlink:to="loc_us-gaap_NetIncomeLoss_75b32ddd-17d1-4bed-865e-e19aebe8f24b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_0c74d03a-c1ad-420f-8f73-005aa8200739" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_26550966-8de3-4c94-8722-aeaf15bf6fb4" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_0c74d03a-c1ad-420f-8f73-005aa8200739" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxesAndTaxCredits_e87db15e-69b9-4a42-a77d-148c582a4018" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DeferredIncomeTaxesAndTaxCredits"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_26550966-8de3-4c94-8722-aeaf15bf6fb4" xlink:to="loc_us-gaap_DeferredIncomeTaxesAndTaxCredits_e87db15e-69b9-4a42-a77d-148c582a4018" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_1e4358a6-f45c-4eed-9724-91f0dfc7275c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_26550966-8de3-4c94-8722-aeaf15bf6fb4" xlink:to="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_1e4358a6-f45c-4eed-9724-91f0dfc7275c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoncashIncomeExpense_97e17d56-64bd-4a6e-a222-62265b2e57eb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherNoncashIncomeExpense"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_26550966-8de3-4c94-8722-aeaf15bf6fb4" xlink:to="loc_us-gaap_OtherNoncashIncomeExpense_97e17d56-64bd-4a6e-a222-62265b2e57eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_cf1fe9c8-c78e-4771-9c17-f3eabe2bbbc2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_26550966-8de3-4c94-8722-aeaf15bf6fb4" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_cf1fe9c8-c78e-4771-9c17-f3eabe2bbbc2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_cd04063f-2721-48ac-ae82-0f115c14e79c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_cf1fe9c8-c78e-4771-9c17-f3eabe2bbbc2" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_cd04063f-2721-48ac-ae82-0f115c14e79c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_5cfe30fc-1eb1-4dde-a3f9-9a25a83c9bb8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInInventories"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_cf1fe9c8-c78e-4771-9c17-f3eabe2bbbc2" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_5cfe30fc-1eb1-4dde-a3f9-9a25a83c9bb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_0301420d-e8f6-40be-84a9-a30268274535" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_cf1fe9c8-c78e-4771-9c17-f3eabe2bbbc2" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_0301420d-e8f6-40be-84a9-a30268274535" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_dc8fcc3a-982e-48fe-82b5-a6a52f7aa93e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_cf1fe9c8-c78e-4771-9c17-f3eabe2bbbc2" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_dc8fcc3a-982e-48fe-82b5-a6a52f7aa93e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable_ca4d5c90-4130-4211-aee7-52a441c6643d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_cf1fe9c8-c78e-4771-9c17-f3eabe2bbbc2" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable_ca4d5c90-4130-4211-aee7-52a441c6643d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_IncreaseDecreaseInNoncurrentTaxLiability_56f86704-e52a-4b5f-ade6-c848d0765ba0" xlink:href="amgn-20210930.xsd#amgn_IncreaseDecreaseInNoncurrentTaxLiability"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_cf1fe9c8-c78e-4771-9c17-f3eabe2bbbc2" xlink:to="loc_amgn_IncreaseDecreaseInNoncurrentTaxLiability_56f86704-e52a-4b5f-ade6-c848d0765ba0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_523648aa-3860-4b23-8f69-d0815624d176" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingLiabilities"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_cf1fe9c8-c78e-4771-9c17-f3eabe2bbbc2" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_523648aa-3860-4b23-8f69-d0815624d176" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4bee42c-b274-456b-8451-1dd6d3fedac3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_26550966-8de3-4c94-8722-aeaf15bf6fb4" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4bee42c-b274-456b-8451-1dd6d3fedac3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4b0a8a8e-6dc9-4092-8b91-1ecfc55b0e86" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_d035736e-09c7-448f-9b1e-473ebbabf3e7" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4b0a8a8e-6dc9-4092-8b91-1ecfc55b0e86" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_346eaecf-b45c-45b9-962d-d25be54d80be" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4b0a8a8e-6dc9-4092-8b91-1ecfc55b0e86" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_346eaecf-b45c-45b9-962d-d25be54d80be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireMarketableSecurities_38c363b5-4e57-4f59-9141-cc914c383cef" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireMarketableSecurities"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4b0a8a8e-6dc9-4092-8b91-1ecfc55b0e86" xlink:to="loc_us-gaap_PaymentsToAcquireMarketableSecurities_38c363b5-4e57-4f59-9141-cc914c383cef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_f358df98-7112-4dab-810f-64afb8a23827" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4b0a8a8e-6dc9-4092-8b91-1ecfc55b0e86" xlink:to="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_f358df98-7112-4dab-810f-64afb8a23827" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_3a2b0fa2-1d1d-4edf-903b-d35a24b419d5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4b0a8a8e-6dc9-4092-8b91-1ecfc55b0e86" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_3a2b0fa2-1d1d-4edf-903b-d35a24b419d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_280dc239-ac68-457e-b121-642b84e786d9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4b0a8a8e-6dc9-4092-8b91-1ecfc55b0e86" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_280dc239-ac68-457e-b121-642b84e786d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireEquityMethodInvestments_273eb6fc-0561-4b46-b4cb-281c9ba35a92" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireEquityMethodInvestments"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4b0a8a8e-6dc9-4092-8b91-1ecfc55b0e86" xlink:to="loc_us-gaap_PaymentsToAcquireEquityMethodInvestments_273eb6fc-0561-4b46-b4cb-281c9ba35a92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_120612bd-7d7f-4939-9eec-d5c24db09c63" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsForProceedsFromOtherInvestingActivities"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4b0a8a8e-6dc9-4092-8b91-1ecfc55b0e86" xlink:to="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_120612bd-7d7f-4939-9eec-d5c24db09c63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_9360e307-edc1-4909-8810-34bb8e8dbe32" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4b0a8a8e-6dc9-4092-8b91-1ecfc55b0e86" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_9360e307-edc1-4909-8810-34bb8e8dbe32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_600dcdd8-e896-47c8-9d7a-6899165f15b5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_d035736e-09c7-448f-9b1e-473ebbabf3e7" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_600dcdd8-e896-47c8-9d7a-6899165f15b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_0452bf79-7415-4cdf-b586-147a5bdcb576" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromIssuanceOfLongTermDebt"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_600dcdd8-e896-47c8-9d7a-6899165f15b5" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_0452bf79-7415-4cdf-b586-147a5bdcb576" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_8033ab99-d714-4fdd-a778-1038b7140d49" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_600dcdd8-e896-47c8-9d7a-6899165f15b5" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_8033ab99-d714-4fdd-a778-1038b7140d49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_ecdb620e-1ce3-43df-9533-f4539f269e67" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_600dcdd8-e896-47c8-9d7a-6899165f15b5" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_ecdb620e-1ce3-43df-9533-f4539f269e67" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDividendsCommonStock_286edf4e-0307-4353-9337-be076e46d2ea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsOfDividendsCommonStock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_600dcdd8-e896-47c8-9d7a-6899165f15b5" xlink:to="loc_us-gaap_PaymentsOfDividendsCommonStock_286edf4e-0307-4353-9337-be076e46d2ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_f280f81e-c04d-4b80-8eca-41cc2da29a05" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromPaymentsForOtherFinancingActivities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_600dcdd8-e896-47c8-9d7a-6899165f15b5" xlink:to="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_f280f81e-c04d-4b80-8eca-41cc2da29a05" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_b7999be2-ddac-4223-b7ea-ad55f2646608" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_600dcdd8-e896-47c8-9d7a-6899165f15b5" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_b7999be2-ddac-4223-b7ea-ad55f2646608" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_e01b5fe4-f87b-49b0-b173-3737979bbc86" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_d035736e-09c7-448f-9b1e-473ebbabf3e7" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_e01b5fe4-f87b-49b0-b173-3737979bbc86" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_715bee69-9862-464f-be02-6762ccb18900" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_d035736e-09c7-448f-9b1e-473ebbabf3e7" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_715bee69-9862-464f-be02-6762ccb18900" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_d91c8703-7163-40b4-8385-6eb14a687c34" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_d035736e-09c7-448f-9b1e-473ebbabf3e7" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_d91c8703-7163-40b4-8385-6eb14a687c34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/Summaryofsignificantaccountingpolicies" xlink:type="simple" xlink:href="amgn-20210930.xsd#Summaryofsignificantaccountingpolicies"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/Summaryofsignificantaccountingpolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_438c0d5e-718e-4a92-a435-e5bb1777caae" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SignificantAccountingPoliciesTextBlock_f4be9064-f4c0-4f87-9e6a-349d053dc2a6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SignificantAccountingPoliciesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_438c0d5e-718e-4a92-a435-e5bb1777caae" xlink:to="loc_us-gaap_SignificantAccountingPoliciesTextBlock_f4be9064-f4c0-4f87-9e6a-349d053dc2a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesPolicies" xlink:type="simple" xlink:href="amgn-20210930.xsd#SummaryofsignificantaccountingpoliciesPolicies"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_8c084be6-4a11-48f0-97e2-715262d5aa7f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_NatureOfOperationsPolicyTextBlock_7ae7327d-7399-46fc-be81-6fbeef07855e" xlink:href="amgn-20210930.xsd#amgn_NatureOfOperationsPolicyTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_8c084be6-4a11-48f0-97e2-715262d5aa7f" xlink:to="loc_amgn_NatureOfOperationsPolicyTextBlock_7ae7327d-7399-46fc-be81-6fbeef07855e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_BasisOfPresentationPolicyTextBlock_6e4a3ea0-b372-4475-b470-9d0cd9c426b5" xlink:href="amgn-20210930.xsd#amgn_BasisOfPresentationPolicyTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_8c084be6-4a11-48f0-97e2-715262d5aa7f" xlink:to="loc_amgn_BasisOfPresentationPolicyTextBlock_6e4a3ea0-b372-4475-b470-9d0cd9c426b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConsolidationPolicyTextBlock_fefa7cab-62b0-4eec-abc0-9f8f041f0228" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConsolidationPolicyTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_8c084be6-4a11-48f0-97e2-715262d5aa7f" xlink:to="loc_us-gaap_ConsolidationPolicyTextBlock_fefa7cab-62b0-4eec-abc0-9f8f041f0228" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UseOfEstimates_4da44e6a-7701-42e5-8dcd-5e24759fcb6f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_UseOfEstimates"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_8c084be6-4a11-48f0-97e2-715262d5aa7f" xlink:to="loc_us-gaap_UseOfEstimates_4da44e6a-7701-42e5-8dcd-5e24759fcb6f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_07e3a3a5-aa95-48d4-bbff-abf17782e0f8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PropertyPlantAndEquipmentPolicyTextBlock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_8c084be6-4a11-48f0-97e2-715262d5aa7f" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_07e3a3a5-aa95-48d4-bbff-abf17782e0f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_bf0d026a-5c23-42c3-8dfe-e657a4443f78" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_8c084be6-4a11-48f0-97e2-715262d5aa7f" xlink:to="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_bf0d026a-5c23-42c3-8dfe-e657a4443f78" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#SummaryofsignificantaccountingpoliciesDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_bd4bf82e-f495-40a9-8d99-8b4b9e7858bb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfOperatingSegments_30a21db4-c4b1-481a-949e-1c4cce2115f7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NumberOfOperatingSegments"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_bd4bf82e-f495-40a9-8d99-8b4b9e7858bb" xlink:to="loc_us-gaap_NumberOfOperatingSegments_30a21db4-c4b1-481a-949e-1c4cce2115f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_cca53fd7-9f13-4201-ac58-5eb57291a1e4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_bd4bf82e-f495-40a9-8d99-8b4b9e7858bb" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_cca53fd7-9f13-4201-ac58-5eb57291a1e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitions" xlink:type="simple" xlink:href="amgn-20210930.xsd#BusinessCombinationsandAssetAcquisitions"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitions" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationAndAssetAcquisitionAbstract_88a2e9bb-7db1-4702-8ee8-7e6c0f3d4bee" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationAndAssetAcquisitionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationDisclosureTextBlock_5611c2f7-f284-4d42-bd59-ec13fd01fa5f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationAndAssetAcquisitionAbstract_88a2e9bb-7db1-4702-8ee8-7e6c0f3d4bee" xlink:to="loc_us-gaap_BusinessCombinationDisclosureTextBlock_5611c2f7-f284-4d42-bd59-ec13fd01fa5f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsTables" xlink:type="simple" xlink:href="amgn-20210930.xsd#BusinessCombinationsandAssetAcquisitionsTables"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationAndAssetAcquisitionAbstract_196d877f-0e1c-4585-ba3d-8846b4ce7d3b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationAndAssetAcquisitionAbstract"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#BusinessCombinationsandAssetAcquisitionsDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationAndAssetAcquisitionAbstract_5d1436fc-27b1-403c-8a36-402bd0887fb3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationAndAssetAcquisitionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_9a8b9cf6-68f4-411d-b8ab-2bb0a2e769b3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationAndAssetAcquisitionAbstract_5d1436fc-27b1-403c-8a36-402bd0887fb3" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_9a8b9cf6-68f4-411d-b8ab-2bb0a2e769b3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_0d307722-28ae-4d64-862a-a557efa092e8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_9a8b9cf6-68f4-411d-b8ab-2bb0a2e769b3" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_0d307722-28ae-4d64-862a-a557efa092e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_20ec96fc-24a0-4c45-a97d-0d13c2aba933" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_0d307722-28ae-4d64-862a-a557efa092e8" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_20ec96fc-24a0-4c45-a97d-0d13c2aba933" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePrimeTherapeuticsIncMember_eb6c0986-eedc-4add-915d-a5a7a6d1b8bf" xlink:href="amgn-20210930.xsd#amgn_FivePrimeTherapeuticsIncMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_20ec96fc-24a0-4c45-a97d-0d13c2aba933" xlink:to="loc_amgn_FivePrimeTherapeuticsIncMember_eb6c0986-eedc-4add-915d-a5a7a6d1b8bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_1ab7a436-11d2-4dd4-ab88-3677ef9bceed" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_9a8b9cf6-68f4-411d-b8ab-2bb0a2e769b3" xlink:to="loc_us-gaap_BusinessAcquisitionLineItems_1ab7a436-11d2-4dd4-ab88-3677ef9bceed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_27fd380e-1b29-4256-8b7e-a2405d4242c3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_1ab7a436-11d2-4dd4-ab88-3677ef9bceed" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_27fd380e-1b29-4256-8b7e-a2405d4242c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_2189d45e-963d-43ef-9889-3ca193942673" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_1ab7a436-11d2-4dd4-ab88-3677ef9bceed" xlink:to="loc_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff_2189d45e-963d-43ef-9889-3ca193942673" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_03bc988b-22df-404c-8608-050ad7319149" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_1ab7a436-11d2-4dd4-ab88-3677ef9bceed" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_03bc988b-22df-404c-8608-050ad7319149" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther_39dc343d-80a6-4ee1-95e8-761040c4cfe9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_1ab7a436-11d2-4dd4-ab88-3677ef9bceed" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther_39dc343d-80a6-4ee1-95e8-761040c4cfe9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets_4a47bd92-3d07-4275-a796-f4e0cd8ca847" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_1ab7a436-11d2-4dd4-ab88-3677ef9bceed" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets_4a47bd92-3d07-4275-a796-f4e0cd8ca847" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/Revenues" xlink:type="simple" xlink:href="amgn-20210930.xsd#Revenues"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/Revenues" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_ffde7c50-e921-45b3-b160-be7d1361719d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerTextBlock_8f5bbbd3-dd8a-4e73-abfc-5ed44a3ee176" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_ffde7c50-e921-45b3-b160-be7d1361719d" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerTextBlock_8f5bbbd3-dd8a-4e73-abfc-5ed44a3ee176" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/RevenuesTables" xlink:type="simple" xlink:href="amgn-20210930.xsd#RevenuesTables"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/RevenuesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_e304dd45-a0a7-4aea-9467-2b16b52eeb34" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueTableTextBlock_36a12231-1202-4925-9311-4b41366bc1c0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DisaggregationOfRevenueTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_e304dd45-a0a7-4aea-9467-2b16b52eeb34" xlink:to="loc_us-gaap_DisaggregationOfRevenueTableTextBlock_36a12231-1202-4925-9311-4b41366bc1c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/RevenuesDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#RevenuesDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/RevenuesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_a2bff0ab-0e5f-47fa-a065-4ac1f8909570" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfOperatingSegments_d4045716-f43a-45c3-a9ba-1b0f2c9dbea9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NumberOfOperatingSegments"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_a2bff0ab-0e5f-47fa-a065-4ac1f8909570" xlink:to="loc_us-gaap_NumberOfOperatingSegments_d4045716-f43a-45c3-a9ba-1b0f2c9dbea9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_8574438d-da32-4e24-8b1c-5d6d2d194fd3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_a2bff0ab-0e5f-47fa-a065-4ac1f8909570" xlink:to="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_8574438d-da32-4e24-8b1c-5d6d2d194fd3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_7ff770ea-5844-4160-be1c-12004dc2e0d3" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_8574438d-da32-4e24-8b1c-5d6d2d194fd3" xlink:to="loc_srt_ProductOrServiceAxis_7ff770ea-5844-4160-be1c-12004dc2e0d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_3066e3a3-9386-41ce-9968-89c12f4a74f0" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_7ff770ea-5844-4160-be1c-12004dc2e0d3" xlink:to="loc_srt_ProductsAndServicesDomain_3066e3a3-9386-41ce-9968-89c12f4a74f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_3066e3a3-9386-41ce-9968-89c12f4a74f0" xlink:to="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_EnbrelMember_ba4cf9ae-af4a-4223-aa7a-27c323edd987" xlink:href="amgn-20210930.xsd#amgn_EnbrelMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_EnbrelMember_ba4cf9ae-af4a-4223-aa7a-27c323edd987" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ProliaMember_de6d8fbb-e16a-4382-b1ad-29f7f844f687" xlink:href="amgn-20210930.xsd#amgn_ProliaMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_ProliaMember_de6d8fbb-e16a-4382-b1ad-29f7f844f687" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtezlaMember_b8632ce9-0c96-49f5-8e8c-a3b2da534332" xlink:href="amgn-20210930.xsd#amgn_OtezlaMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_OtezlaMember_b8632ce9-0c96-49f5-8e8c-a3b2da534332" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_XgevaMember_0d6c22e9-c9be-4b35-9668-d01fe93f7252" xlink:href="amgn-20210930.xsd#amgn_XgevaMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_XgevaMember_0d6c22e9-c9be-4b35-9668-d01fe93f7252" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_NeulastaMember_de8e75ce-2db9-450d-a4a5-2d9739c7ac74" xlink:href="amgn-20210930.xsd#amgn_NeulastaMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_NeulastaMember_de8e75ce-2db9-450d-a4a5-2d9739c7ac74" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AranespMember_467ffdef-5554-4e10-b9ef-2093e2655b21" xlink:href="amgn-20210930.xsd#amgn_AranespMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_AranespMember_467ffdef-5554-4e10-b9ef-2093e2655b21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_RepathaevolocumabMember_3e650132-cfe6-4b01-82a3-66699840e7d9" xlink:href="amgn-20210930.xsd#amgn_RepathaevolocumabMember"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_RepathaevolocumabMember_3e650132-cfe6-4b01-82a3-66699840e7d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_KyprolisMember_db9bf625-8a42-49f9-811b-cefe4ba16795" xlink:href="amgn-20210930.xsd#amgn_KyprolisMember"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_KyprolisMember_db9bf625-8a42-49f9-811b-cefe4ba16795" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherProductsMember_44b9bd68-a5e6-446a-82a1-64cbcd32408b" xlink:href="amgn-20210930.xsd#amgn_OtherProductsMember"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductMember_20d4f516-2270-4f07-8012-daa7875bd073" xlink:to="loc_amgn_OtherProductsMember_44b9bd68-a5e6-446a-82a1-64cbcd32408b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductAndServiceOtherMember_f512d27c-d3f1-4f61-ba4d-19e0f81598bd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductAndServiceOtherMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_3066e3a3-9386-41ce-9968-89c12f4a74f0" xlink:to="loc_us-gaap_ProductAndServiceOtherMember_f512d27c-d3f1-4f61-ba4d-19e0f81598bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementGeographicalAxis_2a55b762-cd04-4f07-9553-b1809e63aba9" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_StatementGeographicalAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_8574438d-da32-4e24-8b1c-5d6d2d194fd3" xlink:to="loc_srt_StatementGeographicalAxis_2a55b762-cd04-4f07-9553-b1809e63aba9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain_0ecd1e14-ad14-41af-922b-f928d89d28ad" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_SegmentGeographicalDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_StatementGeographicalAxis_2a55b762-cd04-4f07-9553-b1809e63aba9" xlink:to="loc_srt_SegmentGeographicalDomain_0ecd1e14-ad14-41af-922b-f928d89d28ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_country_US_ed6f850f-5e2a-4882-8b45-dec637cc0ac5" xlink:href="https://xbrl.sec.gov/country/2021/country-2021.xsd#country_US"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_0ecd1e14-ad14-41af-922b-f928d89d28ad" xlink:to="loc_country_US_ed6f850f-5e2a-4882-8b45-dec637cc0ac5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonUsMember_4c57f565-3125-440a-bfc5-e5af24bb4e72" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NonUsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_0ecd1e14-ad14-41af-922b-f928d89d28ad" xlink:to="loc_us-gaap_NonUsMember_4c57f565-3125-440a-bfc5-e5af24bb4e72" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_8ca69801-dd5e-4c6e-8711-960314cecaf5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_8574438d-da32-4e24-8b1c-5d6d2d194fd3" xlink:to="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_8ca69801-dd5e-4c6e-8711-960314cecaf5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_1aeefe0d-865a-49fc-b8f7-dc72da691917" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_8ca69801-dd5e-4c6e-8711-960314cecaf5" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_1aeefe0d-865a-49fc-b8f7-dc72da691917" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/Incometaxes" xlink:type="simple" xlink:href="amgn-20210930.xsd#Incometaxes"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/Incometaxes" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_2032712d-c671-43c5-869e-ac399343e92a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureTextBlock_66db1d66-cfd4-4345-b50d-0decc2bc75c4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_2032712d-c671-43c5-869e-ac399343e92a" xlink:to="loc_us-gaap_IncomeTaxDisclosureTextBlock_66db1d66-cfd4-4345-b50d-0decc2bc75c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/IncometaxesDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#IncometaxesDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/IncometaxesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_6d83f450-e575-4aae-9263-3be2904ecd79" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_8151701d-3638-4a20-b208-58256ca39f99" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperations"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_6d83f450-e575-4aae-9263-3be2904ecd79" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_8151701d-3638-4a20-b208-58256ca39f99" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions_d97ae5e3-62dd-4537-ab0c-ceae767a6b97" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_6d83f450-e575-4aae-9263-3be2904ecd79" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions_d97ae5e3-62dd-4537-ab0c-ceae767a6b97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AlternativeInvestmentNetGainLoss_6b258998-4e6c-4e8b-95e1-fe608f22c104" xlink:href="amgn-20210930.xsd#amgn_AlternativeInvestmentNetGainLoss"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_6d83f450-e575-4aae-9263-3be2904ecd79" xlink:to="loc_amgn_AlternativeInvestmentNetGainLoss_6b258998-4e6c-4e8b-95e1-fe608f22c104" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ProposedAdditionalIncomeTax_933dc6ee-5ecd-4773-a9a9-516fe43788bc" xlink:href="amgn-20210930.xsd#amgn_ProposedAdditionalIncomeTax"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_6d83f450-e575-4aae-9263-3be2904ecd79" xlink:to="loc_amgn_ProposedAdditionalIncomeTax_933dc6ee-5ecd-4773-a9a9-516fe43788bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_RepatriationTaxOnProposedAdditionalTax_deb32383-fd96-41de-972e-3a3e5e4c5e86" xlink:href="amgn-20210930.xsd#amgn_RepatriationTaxOnProposedAdditionalTax"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_6d83f450-e575-4aae-9263-3be2904ecd79" xlink:to="loc_amgn_RepatriationTaxOnProposedAdditionalTax_deb32383-fd96-41de-972e-3a3e5e4c5e86" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/Earningspershare" xlink:type="simple" xlink:href="amgn-20210930.xsd#Earningspershare"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/Earningspershare" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_f73c5d3e-f9f0-4b8d-97d6-345b163583e6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareTextBlock_7692867e-abf7-4179-b2ab-5d4221e9af08" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_f73c5d3e-f9f0-4b8d-97d6-345b163583e6" xlink:to="loc_us-gaap_EarningsPerShareTextBlock_7692867e-abf7-4179-b2ab-5d4221e9af08" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/EarningspershareTables" xlink:type="simple" xlink:href="amgn-20210930.xsd#EarningspershareTables"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/EarningspershareTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_24cbae3b-2f48-4d70-8f86-da0b3b4e68be" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_e7693177-89e3-4d11-a588-a423e4d48d45" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_24cbae3b-2f48-4d70-8f86-da0b3b4e68be" xlink:to="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_e7693177-89e3-4d11-a588-a423e4d48d45" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/EarningspershareDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#EarningspershareDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/EarningspershareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_0da3ebf7-0596-4524-a93c-aeaca15503cd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_BasicAndDilutedEarningPerShareAbstract_7f86416e-1758-458a-8230-ee69eb4b0b89" xlink:href="amgn-20210930.xsd#amgn_BasicAndDilutedEarningPerShareAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_0da3ebf7-0596-4524-a93c-aeaca15503cd" xlink:to="loc_amgn_BasicAndDilutedEarningPerShareAbstract_7f86416e-1758-458a-8230-ee69eb4b0b89" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAbstract_3253a0f8-0f69-4258-90d5-f5bdba7caed9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLossAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_BasicAndDilutedEarningPerShareAbstract_7f86416e-1758-458a-8230-ee69eb4b0b89" xlink:to="loc_us-gaap_NetIncomeLossAbstract_3253a0f8-0f69-4258-90d5-f5bdba7caed9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_93061668-770e-4da3-9ed0-56a38711412d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetIncomeLossAbstract_3253a0f8-0f69-4258-90d5-f5bdba7caed9" xlink:to="loc_us-gaap_NetIncomeLoss_93061668-770e-4da3-9ed0-56a38711412d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_283d1a05-98f9-435e-8416-4ce58ea51ed6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_BasicAndDilutedEarningPerShareAbstract_7f86416e-1758-458a-8230-ee69eb4b0b89" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_283d1a05-98f9-435e-8416-4ce58ea51ed6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_0271a251-dfcf-4c9b-bdb2-efa180c15fdc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_283d1a05-98f9-435e-8416-4ce58ea51ed6" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_0271a251-dfcf-4c9b-bdb2-efa180c15fdc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_190cd362-2dbc-4520-adcf-80106c4f3157" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_283d1a05-98f9-435e-8416-4ce58ea51ed6" xlink:to="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_190cd362-2dbc-4520-adcf-80106c4f3157" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_bce8d58c-b156-4580-8437-67b0e021d5c6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_283d1a05-98f9-435e-8416-4ce58ea51ed6" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_bce8d58c-b156-4580-8437-67b0e021d5c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_50fed891-f0dc-4ac9-83cf-6e61ddf9ecbd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareBasic"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_BasicAndDilutedEarningPerShareAbstract_7f86416e-1758-458a-8230-ee69eb4b0b89" xlink:to="loc_us-gaap_EarningsPerShareBasic_50fed891-f0dc-4ac9-83cf-6e61ddf9ecbd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_99997b47-321a-4b1d-847c-35ab40a28a6b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareDiluted"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_BasicAndDilutedEarningPerShareAbstract_7f86416e-1758-458a-8230-ee69eb4b0b89" xlink:to="loc_us-gaap_EarningsPerShareDiluted_99997b47-321a-4b1d-847c-35ab40a28a6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/Collaborations" xlink:type="simple" xlink:href="amgn-20210930.xsd#Collaborations"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/Collaborations" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_dd4ca50a-d225-4d2c-ae7d-547e054e2f1c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_a5bd0691-ec6d-4d6a-861c-26c1f288bbf2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CollaborativeArrangementDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_dd4ca50a-d225-4d2c-ae7d-547e054e2f1c" xlink:to="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_a5bd0691-ec6d-4d6a-861c-26c1f288bbf2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/CollaborationsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#CollaborationsDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/CollaborationsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_5aface2e-366e-46e8-83a8-a4cc20141767" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_da5e15af-cca0-45aa-a28f-522a1deed315" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_5aface2e-366e-46e8-83a8-a4cc20141767" xlink:to="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_da5e15af-cca0-45aa-a28f-522a1deed315" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfArrangementAxis_3ce18461-9a24-4202-9928-d6a044033551" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TypeOfArrangementAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_da5e15af-cca0-45aa-a28f-522a1deed315" xlink:to="loc_us-gaap_TypeOfArrangementAxis_3ce18461-9a24-4202-9928-d6a044033551" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_12b2dbe6-958b-46d3-95c4-a7852d1bfcca" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfArrangementAxis_3ce18461-9a24-4202-9928-d6a044033551" xlink:to="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_12b2dbe6-958b-46d3-95c4-a7852d1bfcca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_BeiGeneMember_2bd2f05a-86aa-4bc0-9a6c-e031b579b9e9" xlink:href="amgn-20210930.xsd#amgn_BeiGeneMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_12b2dbe6-958b-46d3-95c4-a7852d1bfcca" xlink:to="loc_amgn_BeiGeneMember_2bd2f05a-86aa-4bc0-9a6c-e031b579b9e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_KyowaKirinCoLtdMember_e0c1fead-8a43-4b34-b3cd-0ed613e6db1d" xlink:href="amgn-20210930.xsd#amgn_KyowaKirinCoLtdMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_12b2dbe6-958b-46d3-95c4-a7852d1bfcca" xlink:to="loc_amgn_KyowaKirinCoLtdMember_e0c1fead-8a43-4b34-b3cd-0ed613e6db1d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_180d4380-7518-42a7-b5c2-41dc23702468" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_da5e15af-cca0-45aa-a28f-522a1deed315" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_180d4380-7518-42a7-b5c2-41dc23702468" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_95959d1b-c25a-4d7a-b187-5a7c6123044a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_180d4380-7518-42a7-b5c2-41dc23702468" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_95959d1b-c25a-4d7a-b187-5a7c6123044a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_e7500688-85f7-4736-ac25-63660a940626" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_95959d1b-c25a-4d7a-b187-5a7c6123044a" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_e7500688-85f7-4736-ac25-63660a940626" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_cf9f7420-346f-4810-a87d-9742d9508fee" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BalanceSheetLocationAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_da5e15af-cca0-45aa-a28f-522a1deed315" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_cf9f7420-346f-4810-a87d-9742d9508fee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_002ac029-3bb7-40a6-a3a2-cbb3ff53b9de" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BalanceSheetLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_cf9f7420-346f-4810-a87d-9742d9508fee" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_002ac029-3bb7-40a6-a3a2-cbb3ff53b9de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCurrentAssetsMember_d14e9d37-cc5d-4559-b562-0ab1823751c5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherCurrentAssetsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_002ac029-3bb7-40a6-a3a2-cbb3ff53b9de" xlink:to="loc_us-gaap_OtherCurrentAssetsMember_d14e9d37-cc5d-4559-b562-0ab1823751c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_0ba56a67-4757-43ba-8a2b-01a446c12102" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_da5e15af-cca0-45aa-a28f-522a1deed315" xlink:to="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_0ba56a67-4757-43ba-8a2b-01a446c12102" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross_cc5e5a81-70bd-4006-ad55-83ebc3af4489" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_0ba56a67-4757-43ba-8a2b-01a446c12102" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross_cc5e5a81-70bd-4006-ad55-83ebc3af4489" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RecoveryOfDirectCosts_082d0e2e-8b7e-4f8d-aea4-f7868129210f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RecoveryOfDirectCosts"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_0ba56a67-4757-43ba-8a2b-01a446c12102" xlink:to="loc_us-gaap_RecoveryOfDirectCosts_082d0e2e-8b7e-4f8d-aea4-f7868129210f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_RecoveryOfDirectCostsReceivable_4602e225-3ff5-4552-838b-534ff9797059" xlink:href="amgn-20210930.xsd#amgn_RecoveryOfDirectCostsReceivable"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_0ba56a67-4757-43ba-8a2b-01a446c12102" xlink:to="loc_amgn_RecoveryOfDirectCostsReceivable_4602e225-3ff5-4552-838b-534ff9797059" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_UpFrontPayment_383648c8-41d3-4bbe-81bb-82d9242451e5" xlink:href="amgn-20210930.xsd#amgn_UpFrontPayment"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_0ba56a67-4757-43ba-8a2b-01a446c12102" xlink:to="loc_amgn_UpFrontPayment_383648c8-41d3-4bbe-81bb-82d9242451e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments_9897dfc2-e55f-49ea-95b5-12ba2d222902" xlink:href="amgn-20210930.xsd#amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_0ba56a67-4757-43ba-8a2b-01a446c12102" xlink:to="loc_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments_9897dfc2-e55f-49ea-95b5-12ba2d222902" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/Investments" xlink:type="simple" xlink:href="amgn-20210930.xsd#Investments"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/Investments" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_d9a66e44-80c0-4193-8897-7224d49a2a38" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock_f7abb8f1-6dc0-49ea-9d23-7e79299b567b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_d9a66e44-80c0-4193-8897-7224d49a2a38" xlink:to="loc_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock_f7abb8f1-6dc0-49ea-9d23-7e79299b567b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InvestmentsTables" xlink:type="simple" xlink:href="amgn-20210930.xsd#InvestmentsTables"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/InvestmentsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_4230e8ce-3186-4691-a37c-865094cccb4b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock_01fca0e0-5cbb-479c-ab4b-9cd75d181a37" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_4230e8ce-3186-4691-a37c-865094cccb4b" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock_01fca0e0-5cbb-479c-ab4b-9cd75d181a37" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock_e674f7f7-ca4c-440c-b1f5-0081f240d2c3" xlink:href="amgn-20210930.xsd#amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_4230e8ce-3186-4691-a37c-865094cccb4b" xlink:to="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock_e674f7f7-ca4c-440c-b1f5-0081f240d2c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock_fddf8293-50c5-49cd-9bf8-a1710099d4c5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_4230e8ce-3186-4691-a37c-865094cccb4b" xlink:to="loc_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock_fddf8293-50c5-49cd-9bf8-a1710099d4c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InvestmentsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#InvestmentsDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/InvestmentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_07c335ad-a254-451c-a943-7e845b2d5778" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_ac09d47f-0104-47c5-b935-c9f3750782ae" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_07c335ad-a254-451c-a943-7e845b2d5778" xlink:to="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_ac09d47f-0104-47c5-b935-c9f3750782ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_502e3d69-6e40-4278-a110-24f4eabb4630" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_ac09d47f-0104-47c5-b935-c9f3750782ae" xlink:to="loc_us-gaap_FinancialInstrumentAxis_502e3d69-6e40-4278-a110-24f4eabb4630" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_502e3d69-6e40-4278-a110-24f4eabb4630" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasurySecuritiesMember_65a61102-cd41-4b05-b60f-d302cf50a3ab" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USTreasurySecuritiesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_us-gaap_USTreasurySecuritiesMember_65a61102-cd41-4b05-b60f-d302cf50a3ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasuryBillSecuritiesMember_f884fb1f-526a-4e7f-800c-4fe1cdb30134" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USTreasuryBillSecuritiesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_us-gaap_USTreasuryBillSecuritiesMember_f884fb1f-526a-4e7f-800c-4fe1cdb30134" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_bc9ab264-03b8-4f5e-9d10-a5606810e8d0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USGovernmentAgenciesDebtSecuritiesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_bc9ab264-03b8-4f5e-9d10-a5606810e8d0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_ff5164c5-d2eb-4436-8368-ae56c08a45bc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignGovernmentDebtSecuritiesMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_ff5164c5-d2eb-4436-8368-ae56c08a45bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesFinancialMember_91e42795-e536-4833-b846-08f3f557688f" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesFinancialMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_amgn_CorporateDebtSecuritiesFinancialMember_91e42795-e536-4833-b846-08f3f557688f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesIndustrialMember_9e5e513e-247b-4263-a1cb-078efe81e068" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesIndustrialMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_amgn_CorporateDebtSecuritiesIndustrialMember_9e5e513e-247b-4263-a1cb-078efe81e068" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesOtherMember_03c02b51-d8ef-402b-833d-a2c38743a3e9" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesOtherMember"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_amgn_CorporateDebtSecuritiesOtherMember_03c02b51-d8ef-402b-833d-a2c38743a3e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_5dee3023-a73c-48de-980e-51df1b5cc2bd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResidentialMortgageBackedSecuritiesMember"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_5dee3023-a73c-48de-980e-51df1b5cc2bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetBackedSecuritiesMember_268592ef-1506-4e02-94c4-e7a711a6fa50" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetBackedSecuritiesMember"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_us-gaap_AssetBackedSecuritiesMember_268592ef-1506-4e02-94c4-e7a711a6fa50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MoneyMarketFundsMember_20a48b01-8e53-4472-af08-3d518ebff32b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MoneyMarketFundsMember"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_us-gaap_MoneyMarketFundsMember_20a48b01-8e53-4472-af08-3d518ebff32b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherShortTermInterestBearingSecuritiesMember_d7016f8f-3a97-4bd5-9041-56a0c0fd9baf" xlink:href="amgn-20210930.xsd#amgn_OtherShortTermInterestBearingSecuritiesMember"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_66bdb254-7bf0-433c-ae48-ef9fa0f9a29b" xlink:to="loc_amgn_OtherShortTermInterestBearingSecuritiesMember_d7016f8f-3a97-4bd5-9041-56a0c0fd9baf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_a62ccaaa-05c1-48fb-b4b5-5d8d53c4097a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_ac09d47f-0104-47c5-b935-c9f3750782ae" xlink:to="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_a62ccaaa-05c1-48fb-b4b5-5d8d53c4097a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_1400da32-2299-4de4-811a-3c56c706d1e5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_a62ccaaa-05c1-48fb-b4b5-5d8d53c4097a" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_1400da32-2299-4de4-811a-3c56c706d1e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_54d2ca50-57da-419c-89ca-9af04ad87176" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_a62ccaaa-05c1-48fb-b4b5-5d8d53c4097a" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_54d2ca50-57da-419c-89ca-9af04ad87176" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_9ab8a13f-49e2-492b-9217-d9e143f0f0cd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_a62ccaaa-05c1-48fb-b4b5-5d8d53c4097a" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_9ab8a13f-49e2-492b-9217-d9e143f0f0cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_1b522a93-eda1-4674-b271-2238b1b70756" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_a62ccaaa-05c1-48fb-b4b5-5d8d53c4097a" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_1b522a93-eda1-4674-b271-2238b1b70756" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#InvestmentsFairValuesbyClassificationDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_0ef5fb2e-20d2-4ccc-b1a1-762627b647d9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_63a78cbe-7587-46d5-9128-05bae29b685e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_0ef5fb2e-20d2-4ccc-b1a1-762627b647d9" xlink:to="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_63a78cbe-7587-46d5-9128-05bae29b685e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_9b824acf-1681-415c-9445-d7bec1ca55a9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_63a78cbe-7587-46d5-9128-05bae29b685e" xlink:to="loc_us-gaap_FinancialInstrumentAxis_9b824acf-1681-415c-9445-d7bec1ca55a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_ff4d72e9-a405-4b8c-aba5-f564f687bf18" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_9b824acf-1681-415c-9445-d7bec1ca55a9" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_ff4d72e9-a405-4b8c-aba5-f564f687bf18" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AvailableForSalesInvestmentsMember_bdfe9f55-2574-4c03-bc8d-c1f04ddc80bb" xlink:href="amgn-20210930.xsd#amgn_AvailableForSalesInvestmentsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_ff4d72e9-a405-4b8c-aba5-f564f687bf18" xlink:to="loc_amgn_AvailableForSalesInvestmentsMember_bdfe9f55-2574-4c03-bc8d-c1f04ddc80bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_ddd641b7-853a-4f1b-949d-80a2ea1164e8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_63a78cbe-7587-46d5-9128-05bae29b685e" xlink:to="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_ddd641b7-853a-4f1b-949d-80a2ea1164e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract_803038e1-d64c-4683-ac19-94e5f7a08586" xlink:href="amgn-20210930.xsd#amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_ddd641b7-853a-4f1b-949d-80a2ea1164e8" xlink:to="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract_803038e1-d64c-4683-ac19-94e5f7a08586" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_041ffce8-103e-4148-8d29-85d23a06ea7c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract_803038e1-d64c-4683-ac19-94e5f7a08586" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_041ffce8-103e-4148-8d29-85d23a06ea7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_8ce72115-fc0d-44f1-8264-927bd7caba6e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract_803038e1-d64c-4683-ac19-94e5f7a08586" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_8ce72115-fc0d-44f1-8264-927bd7caba6e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_99eb2ed3-fb07-4921-b9e4-b1d166af4940" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract_803038e1-d64c-4683-ac19-94e5f7a08586" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_99eb2ed3-fb07-4921-b9e4-b1d166af4940" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InvestmentsAvailableforsaleInvestmentsDetailsTextual" xlink:type="simple" xlink:href="amgn-20210930.xsd#InvestmentsAvailableforsaleInvestmentsDetailsTextual"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/InvestmentsAvailableforsaleInvestmentsDetailsTextual" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_bb5d2e94-d7f6-4b42-8e53-52c8ec5820e4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Cash_0962a066-1952-4673-a91e-73fb1df6b175" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Cash"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_bb5d2e94-d7f6-4b42-8e53-52c8ec5820e4" xlink:to="loc_us-gaap_Cash_0962a066-1952-4673-a91e-73fb1df6b175" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGain_096228d0-eaf2-4100-af4f-24362c889649" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleRealizedGain"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_bb5d2e94-d7f6-4b42-8e53-52c8ec5820e4" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGain_096228d0-eaf2-4100-af4f-24362c889649" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss_54178037-45c9-4ad1-a577-c95c99d655cf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_bb5d2e94-d7f6-4b42-8e53-52c8ec5820e4" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss_54178037-45c9-4ad1-a577-c95c99d655cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#InvestmentsFairValuesbyContractualMaturityDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_1a94ee0e-6aad-4da4-98d5-88e76584db7c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_1c4fc21d-3b47-4cf7-8b19-e74376afa07a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_1a94ee0e-6aad-4da4-98d5-88e76584db7c" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_1c4fc21d-3b47-4cf7-8b19-e74376afa07a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue_66513709-0c5a-49b4-be84-de248b797948" xlink:href="amgn-20210930.xsd#amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_1a94ee0e-6aad-4da4-98d5-88e76584db7c" xlink:to="loc_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue_66513709-0c5a-49b4-be84-de248b797948" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue_d191fd36-6541-42ec-a6f1-a3cf4233f06e" xlink:href="amgn-20210930.xsd#amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_1a94ee0e-6aad-4da4-98d5-88e76584db7c" xlink:to="loc_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue_d191fd36-6541-42ec-a6f1-a3cf4233f06e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_f85046b9-d6bc-4cb6-9727-aadf60f8eec5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_1a94ee0e-6aad-4da4-98d5-88e76584db7c" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_f85046b9-d6bc-4cb6-9727-aadf60f8eec5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_fbbbc778-ecdc-4844-9df5-d1a76e4f1f85" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_1a94ee0e-6aad-4da4-98d5-88e76584db7c" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_fbbbc778-ecdc-4844-9df5-d1a76e4f1f85" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual" xlink:type="simple" xlink:href="amgn-20210930.xsd#InvestmentsEquitySecuritiesDetailsTextual"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_752037ca-70b8-4955-b3ba-b0411833c9be" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleTable_dc6b2bdd-0afe-4721-8141-1cb5d76f714f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_752037ca-70b8-4955-b3ba-b0411833c9be" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleTable_dc6b2bdd-0afe-4721-8141-1cb5d76f714f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1be4c653-5c6c-4f7a-87fc-2131d528c824" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleTable_dc6b2bdd-0afe-4721-8141-1cb5d76f714f" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1be4c653-5c6c-4f7a-87fc-2131d528c824" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0652bf8f-25f5-4600-86d5-6b6847e79ebf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1be4c653-5c6c-4f7a-87fc-2131d528c824" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0652bf8f-25f5-4600-86d5-6b6847e79ebf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_629fc006-e61b-4fb0-b4be-1cf525fc595e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0652bf8f-25f5-4600-86d5-6b6847e79ebf" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_629fc006-e61b-4fb0-b4be-1cf525fc595e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6c0f24ca-f009-446e-abcf-92daa77833ed" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleTable_dc6b2bdd-0afe-4721-8141-1cb5d76f714f" xlink:to="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6c0f24ca-f009-446e-abcf-92daa77833ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNi_abce743b-2485-45e6-a6ac-759c4b4e456b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesFvNi"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6c0f24ca-f009-446e-abcf-92daa77833ed" xlink:to="loc_us-gaap_EquitySecuritiesFvNi_abce743b-2485-45e6-a6ac-759c4b4e456b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss_fd7a09dc-616c-431c-88ac-921546479281" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6c0f24ca-f009-446e-abcf-92daa77833ed" xlink:to="loc_us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss_fd7a09dc-616c-431c-88ac-921546479281" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount_c5750a92-8c8b-47c7-b3c0-d3c9b4683431" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6c0f24ca-f009-446e-abcf-92daa77833ed" xlink:to="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount_c5750a92-8c8b-47c7-b3c0-d3c9b4683431" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_ef2f4423-83b3-48f1-941b-121a18fe6135" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestments"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6c0f24ca-f009-446e-abcf-92daa77833ed" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_ef2f4423-83b3-48f1-941b-121a18fe6135" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount_948979d7-365d-455a-96e0-7da84252f778" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_6c0f24ca-f009-446e-abcf-92daa77833ed" xlink:to="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount_948979d7-365d-455a-96e0-7da84252f778" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_b93f983f-d51e-4fee-80a1-be6f438904a5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_b93f983f-d51e-4fee-80a1-be6f438904a5" xlink:to="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_f6592fe0-ed31-4f9c-a9a2-0eed67af7f0d" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:to="loc_srt_RangeAxis_f6592fe0-ed31-4f9c-a9a2-0eed67af7f0d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_bc5316d4-4a2c-4886-8469-502a08f77c6a" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_f6592fe0-ed31-4f9c-a9a2-0eed67af7f0d" xlink:to="loc_srt_RangeMember_bc5316d4-4a2c-4886-8469-502a08f77c6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_160642ca-47e6-4547-9ff7-1a30f99bcd08" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_bc5316d4-4a2c-4886-8469-502a08f77c6a" xlink:to="loc_srt_MinimumMember_160642ca-47e6-4547-9ff7-1a30f99bcd08" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_e0126858-c223-45c4-811d-7e2a1a501cb2" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_bc5316d4-4a2c-4886-8469-502a08f77c6a" xlink:to="loc_srt_MaximumMember_e0126858-c223-45c4-811d-7e2a1a501cb2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_61809484-e91a-4123-82a9-dde6423c6ef4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_61809484-e91a-4123-82a9-dde6423c6ef4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_f69df2ec-5c75-4aec-a100-6df710d14239" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_61809484-e91a-4123-82a9-dde6423c6ef4" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_f69df2ec-5c75-4aec-a100-6df710d14239" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_BeiGeneMember_02a19e17-37b3-4887-84d6-b74c1c71122d" xlink:href="amgn-20210930.xsd#amgn_BeiGeneMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_f69df2ec-5c75-4aec-a100-6df710d14239" xlink:to="loc_amgn_BeiGeneMember_02a19e17-37b3-4887-84d6-b74c1c71122d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_NeumoraTherapeuticsIncMember_36007dd5-b635-4b06-bfb8-47ce46482da8" xlink:href="amgn-20210930.xsd#amgn_NeumoraTherapeuticsIncMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_f69df2ec-5c75-4aec-a100-6df710d14239" xlink:to="loc_amgn_NeumoraTherapeuticsIncMember_36007dd5-b635-4b06-bfb8-47ce46482da8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeAxis_797d86fb-c466-41e9-8999-6c0597e4f9e1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentTypeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:to="loc_us-gaap_InvestmentTypeAxis_797d86fb-c466-41e9-8999-6c0597e4f9e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeCategorizationMember_17f78e7c-19ae-46a8-bf99-8c0f1f7f8a85" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentTypeCategorizationMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentTypeAxis_797d86fb-c466-41e9-8999-6c0597e4f9e1" xlink:to="loc_us-gaap_InvestmentTypeCategorizationMember_17f78e7c-19ae-46a8-bf99-8c0f1f7f8a85" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_PartnershipInterestMember_bcc19985-e783-466d-8445-857f1932638b" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_PartnershipInterestMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember_17f78e7c-19ae-46a8-bf99-8c0f1f7f8a85" xlink:to="loc_srt_PartnershipInterestMember_bcc19985-e783-466d-8445-857f1932638b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_03540ea3-d96e-462a-9c6a-0ec9578651a6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_03540ea3-d96e-462a-9c6a-0ec9578651a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_420f8c49-c1a6-4da4-8629-9bb6e197c0e4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_03540ea3-d96e-462a-9c6a-0ec9578651a6" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_420f8c49-c1a6-4da4-8629-9bb6e197c0e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember_0b037561-b49a-4d41-9913-e1dbecd311a6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_420f8c49-c1a6-4da4-8629-9bb6e197c0e4" xlink:to="loc_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember_0b037561-b49a-4d41-9913-e1dbecd311a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_61bec9ed-8749-4346-b767-686772103073" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_61bec9ed-8749-4346-b767-686772103073" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_3afb0699-cc28-4285-a467-f96d31586534" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_61bec9ed-8749-4346-b767-686772103073" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_3afb0699-cc28-4285-a467-f96d31586534" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_b27c1c0d-10a8-4ff0-b917-7cfe1df0b2e6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_3afb0699-cc28-4285-a467-f96d31586534" xlink:to="loc_us-gaap_SubsequentEventMember_b27c1c0d-10a8-4ff0-b917-7cfe1df0b2e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable_0ef2b317-9884-4cba-9340-f446f8f7b79f" xlink:to="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestments_a9db1116-4110-4573-b496-2ca26dc8cf2a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestments"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_EquityMethodInvestments_a9db1116-4110-4573-b496-2ca26dc8cf2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentAggregateCost_cac31594-9473-46e0-bd73-b5d0cbd52f2a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentAggregateCost"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_EquityMethodInvestmentAggregateCost_cac31594-9473-46e0-bd73-b5d0cbd52f2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AlternativeInvestment_7d2eff53-c3a0-4f54-a727-a3f8923ee64e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AlternativeInvestment"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_AlternativeInvestment_7d2eff53-c3a0-4f54-a727-a3f8923ee64e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AlternativeInvestmentNetGainLoss_054d42ef-f2f4-4753-a565-491e1717ec8f" xlink:href="amgn-20210930.xsd#amgn_AlternativeInvestmentNetGainLoss"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_amgn_AlternativeInvestmentNetGainLoss_054d42ef-f2f4-4753-a565-491e1717ec8f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_753723d4-5c40-4db5-a0e5-b9bac2e74a7e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentOwnershipPercentage"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_753723d4-5c40-4db5-a0e5-b9bac2e74a7e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentQuotedMarketValue_9f3351dd-98e2-4963-adea-28fa74f636b8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentQuotedMarketValue"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_EquityMethodInvestmentQuotedMarketValue_9f3351dd-98e2-4963-adea-28fa74f636b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity_880496c1-b24c-4533-870d-c52060ddd27b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity_880496c1-b24c-4533-870d-c52060ddd27b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_6fe43d66-7040-48de-b3a2-ebd2dab2aee5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_6fe43d66-7040-48de-b3a2-ebd2dab2aee5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentsFairValueDisclosure_0a1a4c8b-96c6-47d4-8162-01365f7b31c9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityMethodInvestmentsFairValueDisclosure"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_EquityMethodInvestmentsFairValueDisclosure_0a1a4c8b-96c6-47d4-8162-01365f7b31c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_EquityMethodInvestmentChangeInCarryingValue_954a7685-d27a-4bcf-bec4-c0a134b10955" xlink:href="amgn-20210930.xsd#amgn_EquityMethodInvestmentChangeInCarryingValue"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_amgn_EquityMethodInvestmentChangeInCarryingValue_954a7685-d27a-4bcf-bec4-c0a134b10955" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_ba28fee1-39bf-4391-ae28-7479549f01c1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestments"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_ba28fee1-39bf-4391-ae28-7479549f01c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity_7c373e6b-689e-4385-9193-a35e7b5d99c7" xlink:href="amgn-20210930.xsd#amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity_7c373e6b-689e-4385-9193-a35e7b5d99c7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_EquityMethodInvestmentChangeInCarryingValueOther_7480a973-c2a5-4de7-a22d-643b97b6ffd6" xlink:href="amgn-20210930.xsd#amgn_EquityMethodInvestmentChangeInCarryingValueOther"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_amgn_EquityMethodInvestmentChangeInCarryingValueOther_7480a973-c2a5-4de7-a22d-643b97b6ffd6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireEquityMethodInvestments_d20723b5-9bce-492e-9e09-bdfe795f0530" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireEquityMethodInvestments"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_PaymentsToAcquireEquityMethodInvestments_d20723b5-9bce-492e-9e09-bdfe795f0530" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1_79beaec0-5790-4996-b1e2-b3459a71f8cc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems_7bcc852d-5550-4b38-bc4e-428825aa1abb" xlink:to="loc_us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1_79beaec0-5790-4996-b1e2-b3459a71f8cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/Inventories" xlink:type="simple" xlink:href="amgn-20210930.xsd#Inventories"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/Inventories" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_d409d1f5-a1c0-46fd-a648-87081ddfaa3f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureTextBlock_9686f2e4-e80a-4960-99de-093a4913271d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_d409d1f5-a1c0-46fd-a648-87081ddfaa3f" xlink:to="loc_us-gaap_InventoryDisclosureTextBlock_9686f2e4-e80a-4960-99de-093a4913271d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InventoriesTables" xlink:type="simple" xlink:href="amgn-20210930.xsd#InventoriesTables"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/InventoriesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_31d5244e-b8e1-4de7-86c0-bdee802d0221" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_e9aff9d3-9591-4bf7-adc8-ea6b8d6746b9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfInventoryCurrentTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_31d5244e-b8e1-4de7-86c0-bdee802d0221" xlink:to="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_e9aff9d3-9591-4bf7-adc8-ea6b8d6746b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/InventoriesDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#InventoriesDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/InventoriesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_4383174d-95aa-4eaf-a33f-2e6162010e69" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryRawMaterialsNetOfReserves_03978720-f3e3-4524-8029-a3f2e97adad4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryRawMaterialsNetOfReserves"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_4383174d-95aa-4eaf-a33f-2e6162010e69" xlink:to="loc_us-gaap_InventoryRawMaterialsNetOfReserves_03978720-f3e3-4524-8029-a3f2e97adad4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryWorkInProcessNetOfReserves_548edd8a-5eba-4d26-84f1-f6e7329e8e58" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryWorkInProcessNetOfReserves"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_4383174d-95aa-4eaf-a33f-2e6162010e69" xlink:to="loc_us-gaap_InventoryWorkInProcessNetOfReserves_548edd8a-5eba-4d26-84f1-f6e7329e8e58" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_a2911449-195c-4602-9795-f6f1f144f298" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryFinishedGoodsNetOfReserves"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_4383174d-95aa-4eaf-a33f-2e6162010e69" xlink:to="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_a2911449-195c-4602-9795-f6f1f144f298" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_f7eb8b6b-1423-4b43-b178-390353a53193" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryNet"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_4383174d-95aa-4eaf-a33f-2e6162010e69" xlink:to="loc_us-gaap_InventoryNet_f7eb8b6b-1423-4b43-b178-390353a53193" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/Goodwillandotherintangibleassets" xlink:type="simple" xlink:href="amgn-20210930.xsd#Goodwillandotherintangibleassets"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/Goodwillandotherintangibleassets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_be637f96-4d9e-4294-9bcb-495688300e69" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_dd11d608-67bc-49a6-ae24-bed4003cecab" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_be637f96-4d9e-4294-9bcb-495688300e69" xlink:to="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_dd11d608-67bc-49a6-ae24-bed4003cecab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/GoodwillandotherintangibleassetsTables" xlink:type="simple" xlink:href="amgn-20210930.xsd#GoodwillandotherintangibleassetsTables"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/GoodwillandotherintangibleassetsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_7a8b9f92-4e1d-45a1-837f-899922fb9cf1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfGoodwillTextBlock_e7feadeb-f2f8-48a7-94df-63206dd6cb29" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfGoodwillTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_7a8b9f92-4e1d-45a1-837f-899922fb9cf1" xlink:to="loc_us-gaap_ScheduleOfGoodwillTextBlock_e7feadeb-f2f8-48a7-94df-63206dd6cb29" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ScheduleOfIntangibleAssetsTableTextBlock_d3bffd68-7f65-40f7-8a0f-20b9f51dec87" xlink:href="amgn-20210930.xsd#amgn_ScheduleOfIntangibleAssetsTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_7a8b9f92-4e1d-45a1-837f-899922fb9cf1" xlink:to="loc_amgn_ScheduleOfIntangibleAssetsTableTextBlock_d3bffd68-7f65-40f7-8a0f-20b9f51dec87" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/GoodwillandotherintangibleassetsGoodwillRollForwardDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#GoodwillandotherintangibleassetsGoodwillRollForwardDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/GoodwillandotherintangibleassetsGoodwillRollForwardDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_f27d7f59-53ca-4dc6-b10b-2f5370f0809f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillRollForward_e74bab5e-60be-47dc-a240-bd9e209e3dd6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GoodwillRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_f27d7f59-53ca-4dc6-b10b-2f5370f0809f" xlink:to="loc_us-gaap_GoodwillRollForward_e74bab5e-60be-47dc-a240-bd9e209e3dd6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_875d3e32-9c4b-483f-8244-e61ff06ce8fd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Goodwill"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_e74bab5e-60be-47dc-a240-bd9e209e3dd6" xlink:to="loc_us-gaap_Goodwill_875d3e32-9c4b-483f-8244-e61ff06ce8fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillForeignCurrencyTranslationGainLoss_46d45e37-d6a1-4298-8eec-2a2c06cf492e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GoodwillForeignCurrencyTranslationGainLoss"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_e74bab5e-60be-47dc-a240-bd9e209e3dd6" xlink:to="loc_us-gaap_GoodwillForeignCurrencyTranslationGainLoss_46d45e37-d6a1-4298-8eec-2a2c06cf492e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_8939b9b3-cd04-4999-b685-00886fe29359" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Goodwill"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_e74bab5e-60be-47dc-a240-bd9e209e3dd6" xlink:to="loc_us-gaap_Goodwill_8939b9b3-cd04-4999-b685-00886fe29359" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_e57d8e24-252b-4720-ba1f-273b28447a92" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_57e46cb6-f4e6-444b-9ebe-4888aaf902ca" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_e57d8e24-252b-4720-ba1f-273b28447a92" xlink:to="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_57e46cb6-f4e6-444b-9ebe-4888aaf902ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_9bf36dae-2b87-437c-912d-c57990c84124" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_57e46cb6-f4e6-444b-9ebe-4888aaf902ca" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_9bf36dae-2b87-437c-912d-c57990c84124" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_c862744d-b32f-498e-8dd9-29712c071d56" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_9bf36dae-2b87-437c-912d-c57990c84124" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_c862744d-b32f-498e-8dd9-29712c071d56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InProcessResearchAndDevelopmentMember_92670c44-6be1-4f45-91ba-b3f573d4fe3d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InProcessResearchAndDevelopmentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_c862744d-b32f-498e-8dd9-29712c071d56" xlink:to="loc_us-gaap_InProcessResearchAndDevelopmentMember_92670c44-6be1-4f45-91ba-b3f573d4fe3d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_b6e2a943-d9a7-4501-a472-85e56a84ff92" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_57e46cb6-f4e6-444b-9ebe-4888aaf902ca" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_b6e2a943-d9a7-4501-a472-85e56a84ff92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_c838ea69-87de-467b-af1f-8761d70408d4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_b6e2a943-d9a7-4501-a472-85e56a84ff92" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_c838ea69-87de-467b-af1f-8761d70408d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_241b8f5b-d7f4-4543-a1f0-10f9a38d7108" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_e57d8e24-252b-4720-ba1f-273b28447a92" xlink:to="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_241b8f5b-d7f4-4543-a1f0-10f9a38d7108" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_53ba9f94-1ce7-47df-a4f5-9d1ccb2a96cb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_241b8f5b-d7f4-4543-a1f0-10f9a38d7108" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_53ba9f94-1ce7-47df-a4f5-9d1ccb2a96cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_32678af4-5a31-48da-9652-3aad68943efe" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_53ba9f94-1ce7-47df-a4f5-9d1ccb2a96cb" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_32678af4-5a31-48da-9652-3aad68943efe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DevelopedTechnologyRightsMember_8bded74a-01ef-4660-90b6-7ea36d2cf644" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DevelopedTechnologyRightsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_32678af4-5a31-48da-9652-3aad68943efe" xlink:to="loc_us-gaap_DevelopedTechnologyRightsMember_8bded74a-01ef-4660-90b6-7ea36d2cf644" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LicensingAgreementsMember_55466aab-a592-4dd1-8e06-477c78f06652" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LicensingAgreementsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_32678af4-5a31-48da-9652-3aad68943efe" xlink:to="loc_us-gaap_LicensingAgreementsMember_55466aab-a592-4dd1-8e06-477c78f06652" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketingRelatedIntangibleAssetsMember_39fee953-3301-4126-bd12-8b47cad74afb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MarketingRelatedIntangibleAssetsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_32678af4-5a31-48da-9652-3aad68943efe" xlink:to="loc_us-gaap_MarketingRelatedIntangibleAssetsMember_39fee953-3301-4126-bd12-8b47cad74afb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember_f3dcd2f0-6492-4852-bbb7-1bed6c8f087d" xlink:href="amgn-20210930.xsd#amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_32678af4-5a31-48da-9652-3aad68943efe" xlink:to="loc_amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember_f3dcd2f0-6492-4852-bbb7-1bed6c8f087d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_65ffa905-1c76-4ea0-9d8a-4b095bea4498" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_241b8f5b-d7f4-4543-a1f0-10f9a38d7108" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_65ffa905-1c76-4ea0-9d8a-4b095bea4498" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_4307a436-bb84-4e79-badd-c56566fb8458" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_65ffa905-1c76-4ea0-9d8a-4b095bea4498" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_4307a436-bb84-4e79-badd-c56566fb8458" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_d22a3714-9725-4d08-8767-8b5f3400fae4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_65ffa905-1c76-4ea0-9d8a-4b095bea4498" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_d22a3714-9725-4d08-8767-8b5f3400fae4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_7f857929-1354-4a43-9947-274705edf818" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_65ffa905-1c76-4ea0-9d8a-4b095bea4498" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_7f857929-1354-4a43-9947-274705edf818" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_IdentifiableIntangibleAssetsGross_5612e7df-dacc-4b21-b8f8-25bcbd660a21" xlink:href="amgn-20210930.xsd#amgn_IdentifiableIntangibleAssetsGross"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_e57d8e24-252b-4720-ba1f-273b28447a92" xlink:to="loc_amgn_IdentifiableIntangibleAssetsGross_5612e7df-dacc-4b21-b8f8-25bcbd660a21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization_52f9c9f7-8cb3-4c26-949a-297fc7f7940d" xlink:href="amgn-20210930.xsd#amgn_IdentifiableIntangibleAssetsAccumulatedAmortization"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_e57d8e24-252b-4720-ba1f-273b28447a92" xlink:to="loc_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization_52f9c9f7-8cb3-4c26-949a-297fc7f7940d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_797aa872-35a7-48b7-ac26-1d91e65683f8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_e57d8e24-252b-4720-ba1f-273b28447a92" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_797aa872-35a7-48b7-ac26-1d91e65683f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/GoodwillandotherintangibleassetsDetailsTextual" xlink:type="simple" xlink:href="amgn-20210930.xsd#GoodwillandotherintangibleassetsDetailsTextual"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/GoodwillandotherintangibleassetsDetailsTextual" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_3bb7bf2d-b619-4ee9-87e5-d188e11ccf76" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_24fd4e45-4910-4933-a52b-754ea164044f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_3bb7bf2d-b619-4ee9-87e5-d188e11ccf76" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_24fd4e45-4910-4933-a52b-754ea164044f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_3ce3c9b1-90d3-4202-9d4b-dc4e930848de" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_3bb7bf2d-b619-4ee9-87e5-d188e11ccf76" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_3ce3c9b1-90d3-4202-9d4b-dc4e930848de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_d56f8bdb-a084-4798-9222-011d7587882a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_3bb7bf2d-b619-4ee9-87e5-d188e11ccf76" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_d56f8bdb-a084-4798-9222-011d7587882a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_586d5b5c-6a79-4096-8281-9c325dfd62d1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_3bb7bf2d-b619-4ee9-87e5-d188e11ccf76" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_586d5b5c-6a79-4096-8281-9c325dfd62d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_e5ee615c-f12a-4dd5-9dd9-70236530e27b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_3bb7bf2d-b619-4ee9-87e5-d188e11ccf76" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_e5ee615c-f12a-4dd5-9dd9-70236530e27b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_9b48b5d4-eff5-47e9-84fe-36ab1294b403" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_3bb7bf2d-b619-4ee9-87e5-d188e11ccf76" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_9b48b5d4-eff5-47e9-84fe-36ab1294b403" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_73cf2e30-8009-4b02-b314-c4729e0aa42b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_3bb7bf2d-b619-4ee9-87e5-d188e11ccf76" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_73cf2e30-8009-4b02-b314-c4729e0aa42b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/Financingarrangements" xlink:type="simple" xlink:href="amgn-20210930.xsd#Financingarrangements"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/Financingarrangements" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_b5e33443-1546-4bff-976d-b80f60fc59fa" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureTextBlock_da0ad20c-a53c-41e1-8e71-34986da3bd52" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_b5e33443-1546-4bff-976d-b80f60fc59fa" xlink:to="loc_us-gaap_DebtDisclosureTextBlock_da0ad20c-a53c-41e1-8e71-34986da3bd52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/FinancingarrangementsTables" xlink:type="simple" xlink:href="amgn-20210930.xsd#FinancingarrangementsTables"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/FinancingarrangementsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_b58f10e5-7fca-45b5-8530-539704ba1727" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_6ad5cb6a-8531-479f-b006-852bf9da50e0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfDebtInstrumentsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_b58f10e5-7fca-45b5-8530-539704ba1727" xlink:to="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_6ad5cb6a-8531-479f-b006-852bf9da50e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInterestRateDerivativesTableTextBlock_50b45b8c-92a3-4215-a768-07485da5df97" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfInterestRateDerivativesTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_b58f10e5-7fca-45b5-8530-539704ba1727" xlink:to="loc_us-gaap_ScheduleOfInterestRateDerivativesTableTextBlock_50b45b8c-92a3-4215-a768-07485da5df97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock_78634c37-77be-4bbb-8ffc-7fa611b3651b" xlink:href="amgn-20210930.xsd#amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_b58f10e5-7fca-45b5-8530-539704ba1727" xlink:to="loc_amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock_78634c37-77be-4bbb-8ffc-7fa611b3651b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_36ffef18-c084-4091-889b-74d8406130d4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_ad13080d-be65-47ed-94a2-93edfc65176d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_36ffef18-c084-4091-889b-74d8406130d4" xlink:to="loc_us-gaap_DebtInstrumentTable_ad13080d-be65-47ed-94a2-93edfc65176d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_088a2c5c-9674-4b03-9e4b-13f5c0c88df3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_ad13080d-be65-47ed-94a2-93edfc65176d" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_088a2c5c-9674-4b03-9e4b-13f5c0c88df3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_d6a411cf-5c4d-486b-9707-c6e489ee2e1a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_088a2c5c-9674-4b03-9e4b-13f5c0c88df3" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_d6a411cf-5c4d-486b-9707-c6e489ee2e1a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesPayableToBanksMember_4310b28e-dab7-4b4e-909a-03a706431a34" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NotesPayableToBanksMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_d6a411cf-5c4d-486b-9707-c6e489ee2e1a" xlink:to="loc_us-gaap_NotesPayableToBanksMember_4310b28e-dab7-4b4e-909a-03a706431a34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_88ed0d38-b843-4336-8d56-48f0022b9271" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_ad13080d-be65-47ed-94a2-93edfc65176d" xlink:to="loc_us-gaap_DebtInstrumentAxis_88ed0d38-b843-4336-8d56-48f0022b9271" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_88ed0d38-b843-4336-8d56-48f0022b9271" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointFiveZeroPercentNotesDue2020Member_4af966c6-7f87-4712-8b42-876d9391a1a3" xlink:href="amgn-20210930.xsd#amgn_FourPointFiveZeroPercentNotesDue2020Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FourPointFiveZeroPercentNotesDue2020Member_4af966c6-7f87-4712-8b42-876d9391a1a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_757520f7-c1f1-45f0-9f01-d191205eef31" xlink:href="amgn-20210930.xsd#amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_757520f7-c1f1-45f0-9f01-d191205eef31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FloatingRateNotesDue2020Member_51f2c38d-ad52-4fe1-92b7-db937c90af86" xlink:href="amgn-20210930.xsd#amgn_FloatingRateNotesDue2020Member"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FloatingRateNotesDue2020Member_51f2c38d-ad52-4fe1-92b7-db937c90af86" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointTwoZeroNotesDue2020Member_a2fa0133-78e0-4eef-8bbf-04b3f49256a3" xlink:href="amgn-20210930.xsd#amgn_TwoPointTwoZeroNotesDue2020Member"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointTwoZeroNotesDue2020Member_a2fa0133-78e0-4eef-8bbf-04b3f49256a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointFourFivePercentNotesDue2020Member_f6a54a3d-02d0-416a-b32a-831e2ab1e550" xlink:href="amgn-20210930.xsd#amgn_ThreePointFourFivePercentNotesDue2020Member"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointFourFivePercentNotesDue2020Member_f6a54a3d-02d0-416a-b32a-831e2ab1e550" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointOneZeroPercentNotesDue2021Member_f6e5ff1e-4d44-4c63-a019-193a954c0d7f" xlink:href="amgn-20210930.xsd#amgn_FourPointOneZeroPercentNotesDue2021Member"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FourPointOneZeroPercentNotesDue2021Member_f6e5ff1e-4d44-4c63-a019-193a954c0d7f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_b5e53404-6314-4f3e-9b3a-f4406e2c9974" xlink:href="amgn-20210930.xsd#amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_b5e53404-6314-4f3e-9b3a-f4406e2c9974" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_d486f7f4-dbeb-47e8-873a-d727c05835da" xlink:href="amgn-20210930.xsd#amgn_ThreePointEightSevenFivePercentNotesDue2021Member"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_d486f7f4-dbeb-47e8-873a-d727c05835da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_be716109-47e1-4671-ac66-48f5aba7e213" xlink:href="amgn-20210930.xsd#amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_be716109-47e1-4671-ac66-48f5aba7e213" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_de615baf-0629-4cc4-9f17-ef5478080bc4" xlink:href="amgn-20210930.xsd#amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_de615baf-0629-4cc4-9f17-ef5478080bc4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointSixFiveNotesDue2022Member_c0027964-4417-4d77-b85b-0940e5305a2b" xlink:href="amgn-20210930.xsd#amgn_TwoPointSixFiveNotesDue2022Member"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointSixFiveNotesDue2022Member_c0027964-4417-4d77-b85b-0940e5305a2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_eb1c6536-38a0-4031-95c7-157f43fb742d" xlink:href="amgn-20210930.xsd#amgn_ThreePointSixTwoFivePercentNotesDue2022Member"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_eb1c6536-38a0-4031-95c7-157f43fb742d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_5716f2b9-fd52-440c-83c8-7894d127f589" xlink:href="amgn-20210930.xsd#amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_5716f2b9-fd52-440c-83c8-7894d127f589" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_8caf08c4-fd60-4667-aebc-71d5e702d196" xlink:href="amgn-20210930.xsd#amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_8caf08c4-fd60-4667-aebc-71d5e702d196" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_73e222c4-7ef6-4572-9b28-a2428d3b8161" xlink:href="amgn-20210930.xsd#amgn_ThreePointSixTwoFivePercentNotesDue2024Member"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_73e222c4-7ef6-4572-9b28-a2428d3b8161" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember_4c923ac0-5714-44bc-8baa-7cf79aa24a23" xlink:href="amgn-20210930.xsd#amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember_4c923ac0-5714-44bc-8baa-7cf79aa24a23" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_ee87a604-ac34-4acf-914d-d404ce160535" xlink:href="amgn-20210930.xsd#amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_ee87a604-ac34-4acf-914d-d404ce160535" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_9c9be88a-e0cd-48b0-b843-dc19689c243b" xlink:href="amgn-20210930.xsd#amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_9c9be88a-e0cd-48b0-b843-dc19689c243b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_7f535730-4001-43ef-9213-5739d41aa1a2" xlink:href="amgn-20210930.xsd#amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_7f535730-4001-43ef-9213-5739d41aa1a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_79926e5b-eb1c-46e6-a7a4-2e02db9f47c2" xlink:href="amgn-20210930.xsd#amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_79926e5b-eb1c-46e6-a7a4-2e02db9f47c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember_312fed0a-9f78-4c4f-b19f-5aa8f5cd4d62" xlink:href="amgn-20210930.xsd#amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember_312fed0a-9f78-4c4f-b19f-5aa8f5cd4d62" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointTwoZeroNotesDue2027Member_da37739e-7116-406a-8384-05fa1c190a98" xlink:href="amgn-20210930.xsd#amgn_ThreePointTwoZeroNotesDue2027Member"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointTwoZeroNotesDue2027Member_da37739e-7116-406a-8384-05fa1c190a98" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointSixFivePercent2028NotesMember_44c80fb4-9dc9-4d7c-b6a3-593215fd4d0b" xlink:href="amgn-20210930.xsd#amgn_OnePointSixFivePercent2028NotesMember"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_OnePointSixFivePercent2028NotesMember_44c80fb4-9dc9-4d7c-b6a3-593215fd4d0b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPercentPoundSterlingNotesDue2029Member_36d18026-117d-4313-8898-63d9d22ae3ca" xlink:href="amgn-20210930.xsd#amgn_FourPercentPoundSterlingNotesDue2029Member"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FourPercentPoundSterlingNotesDue2029Member_36d18026-117d-4313-8898-63d9d22ae3ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointFourFivePercentNotesDue2030Member_bde81b0b-6ae4-45a6-a3a8-cf29a91cd9bc" xlink:href="amgn-20210930.xsd#amgn_TwoPointFourFivePercentNotesDue2030Member"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointFourFivePercentNotesDue2030Member_bde81b0b-6ae4-45a6-a3a8-cf29a91cd9bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointThreeZeroPercentNotesDue2031Member_a19f7c54-8458-4374-948e-b170c0012463" xlink:href="amgn-20210930.xsd#amgn_TwoPointThreeZeroPercentNotesDue2031Member"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointThreeZeroPercentNotesDue2031Member_a19f7c54-8458-4374-948e-b170c0012463" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointZeroPercent2032NotesMemberMember_dbf3a147-39f7-4168-95f8-790d2ce422db" xlink:href="amgn-20210930.xsd#amgn_TwoPointZeroPercent2032NotesMemberMember"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointZeroPercent2032NotesMemberMember_dbf3a147-39f7-4168-95f8-790d2ce422db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_6fc89102-eef3-42aa-91b8-5e4db26a8daf" xlink:href="amgn-20210930.xsd#amgn_SixPointThreeSevenFivePercentNotesDue2037Member"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_6fc89102-eef3-42aa-91b8-5e4db26a8daf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_SixPointNineZeroPercentNotesDue2038Member_95acd192-140a-43b7-ba7d-dfc98f107824" xlink:href="amgn-20210930.xsd#amgn_SixPointNineZeroPercentNotesDue2038Member"/>
    <link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_SixPointNineZeroPercentNotesDue2038Member_95acd192-140a-43b7-ba7d-dfc98f107824" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_SixPointFourZeroPercentNotesDue2039Member_3cdbe74e-371a-4a32-b5e8-1ae08fc7f7be" xlink:href="amgn-20210930.xsd#amgn_SixPointFourZeroPercentNotesDue2039Member"/>
    <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_SixPointFourZeroPercentNotesDue2039Member_3cdbe74e-371a-4a32-b5e8-1ae08fc7f7be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointOneFivePercentNotesDue2040Member_d0146d85-deff-44d3-91a5-a2b007696493" xlink:href="amgn-20210930.xsd#amgn_ThreePointOneFivePercentNotesDue2040Member"/>
    <link:presentationArc order="31" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointOneFivePercentNotesDue2040Member_d0146d85-deff-44d3-91a5-a2b007696493" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointSevenFivePercentNotesDue2040Member_036f4812-8983-418e-9158-b9b97226b469" xlink:href="amgn-20210930.xsd#amgn_FivePointSevenFivePercentNotesDue2040Member"/>
    <link:presentationArc order="32" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FivePointSevenFivePercentNotesDue2040Member_036f4812-8983-418e-9158-b9b97226b469" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointEightZeroPercent2041NotesMember_0eaa0ce1-6eed-416d-bc7c-c80b178f2e16" xlink:href="amgn-20210930.xsd#amgn_TwoPointEightZeroPercent2041NotesMember"/>
    <link:presentationArc order="33" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointEightZeroPercent2041NotesMember_0eaa0ce1-6eed-416d-bc7c-c80b178f2e16" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointNineFivePercentNotesDue2041Member_d22dd03d-1f1e-454a-b53c-5b8d852b2896" xlink:href="amgn-20210930.xsd#amgn_FourPointNineFivePercentNotesDue2041Member"/>
    <link:presentationArc order="34" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FourPointNineFivePercentNotesDue2041Member_d22dd03d-1f1e-454a-b53c-5b8d852b2896" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointOneFivePercentNotesDue2041Member_481ab4aa-8eb4-4a25-b236-e4dd024d1fdf" xlink:href="amgn-20210930.xsd#amgn_FivePointOneFivePercentNotesDue2041Member"/>
    <link:presentationArc order="35" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FivePointOneFivePercentNotesDue2041Member_481ab4aa-8eb4-4a25-b236-e4dd024d1fdf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointSixFivePercentNotesDue2042Member_2e42e448-9351-4450-9a34-5aa7126be226" xlink:href="amgn-20210930.xsd#amgn_FivePointSixFivePercentNotesDue2042Member"/>
    <link:presentationArc order="36" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FivePointSixFivePercentNotesDue2042Member_2e42e448-9351-4450-9a34-5aa7126be226" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointThreeSevenFivePercentNotesDue2043Member_4a96aab8-e74f-4e1d-9bad-242bc77ba9e1" xlink:href="amgn-20210930.xsd#amgn_FivePointThreeSevenFivePercentNotesDue2043Member"/>
    <link:presentationArc order="37" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FivePointThreeSevenFivePercentNotesDue2043Member_4a96aab8-e74f-4e1d-9bad-242bc77ba9e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_81d5eeb4-c4c3-4159-bd2b-e9c5600f2b98" xlink:href="amgn-20210930.xsd#amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember"/>
    <link:presentationArc order="38" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_81d5eeb4-c4c3-4159-bd2b-e9c5600f2b98" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_fdaffd75-94c7-439d-94b9-57b74788d9bd" xlink:href="amgn-20210930.xsd#amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember"/>
    <link:presentationArc order="39" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_fdaffd75-94c7-439d-94b9-57b74788d9bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ThreePointThreeSevenFivePercentNotesDue2050Member_1c01b9ff-badb-4075-839f-3bfdbd921d48" xlink:href="amgn-20210930.xsd#amgn_ThreePointThreeSevenFivePercentNotesDue2050Member"/>
    <link:presentationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_ThreePointThreeSevenFivePercentNotesDue2050Member_1c01b9ff-badb-4075-839f-3bfdbd921d48" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_22f3c910-1df9-4868-8600-71985f78e20a" xlink:href="amgn-20210930.xsd#amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember"/>
    <link:presentationArc order="41" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_22f3c910-1df9-4868-8600-71985f78e20a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_A300NotesDue20523002052NotesMember_ee19846b-156f-42cc-9b64-800474f8973c" xlink:href="amgn-20210930.xsd#amgn_A300NotesDue20523002052NotesMember"/>
    <link:presentationArc order="42" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_A300NotesDue20523002052NotesMember_ee19846b-156f-42cc-9b64-800474f8973c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember_6761fcf9-fddf-402c-bb79-98fe47bf62bb" xlink:href="amgn-20210930.xsd#amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember"/>
    <link:presentationArc order="43" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember_6761fcf9-fddf-402c-bb79-98fe47bf62bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherNotesDue2097Member_e4869098-7d86-480a-800a-589202936ae9" xlink:href="amgn-20210930.xsd#amgn_OtherNotesDue2097Member"/>
    <link:presentationArc order="44" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9774bf46-88ff-4f3e-9e5d-54cfae441307" xlink:to="loc_amgn_OtherNotesDue2097Member_e4869098-7d86-480a-800a-589202936ae9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_ad13080d-be65-47ed-94a2-93edfc65176d" xlink:to="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_fdb29e68-21a2-4a70-a4bf-8c9a3b52845e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_fdb29e68-21a2-4a70-a4bf-8c9a3b52845e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_568ad685-382d-4063-be2a-058ced9493ab" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_568ad685-382d-4063-be2a-058ced9493ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_d110d79a-0a12-46f8-8f2a-6b18a169c3ad" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_d110d79a-0a12-46f8-8f2a-6b18a169c3ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease_19431668-802b-41e9-b486-182c0ba65154" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease_19431668-802b-41e9-b486-182c0ba65154" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLongTermDebt_d4da2e54-e736-4b3f-8361-ab4d7ed04ec2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherLongTermDebt"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_OtherLongTermDebt_d4da2e54-e736-4b3f-8361-ab4d7ed04ec2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_fb248b08-e9ae-46e5-9b24-4212047561cf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebt"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_LongTermDebt_fb248b08-e9ae-46e5-9b24-4212047561cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_804ced31-af9d-4d38-92cc-b41aacb36759" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_LongTermDebtCurrent_804ced31-af9d-4d38-92cc-b41aacb36759" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_096fc810-1cca-4445-8688-db67e9ccd7bf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_096fc810-1cca-4445-8688-db67e9ccd7bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_b9d1aa10-a111-4b19-9750-05b1a598642a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentFaceAmount"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_b9d1aa10-a111-4b19-9750-05b1a598642a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent_cb7fa4e8-0bc7-40ea-b6ce-7861ac06095b" xlink:href="amgn-20210930.xsd#amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_88fbdb7d-3900-4be6-8a72-bda218f880be" xlink:to="loc_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent_cb7fa4e8-0bc7-40ea-b6ce-7861ac06095b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DebtExchangeAdditionalCashConsideration_cea65700-69f0-4978-9a8b-e911183daeee" xlink:href="amgn-20210930.xsd#amgn_DebtExchangeAdditionalCashConsideration"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_36ffef18-c084-4091-889b-74d8406130d4" xlink:to="loc_amgn_DebtExchangeAdditionalCashConsideration_cea65700-69f0-4978-9a8b-e911183daeee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/FinancingarrangementsDetailsTextual" xlink:type="simple" xlink:href="amgn-20210930.xsd#FinancingarrangementsDetailsTextual"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/FinancingarrangementsDetailsTextual" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_d8821e0c-c4ea-4c04-9e23-1ee4b403fa16" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_2758bf5d-4533-4add-9e02-2982b7965919" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_d8821e0c-c4ea-4c04-9e23-1ee4b403fa16" xlink:to="loc_us-gaap_DebtInstrumentTable_2758bf5d-4533-4add-9e02-2982b7965919" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_beeb000a-0e44-43ce-9995-ab812cb2de9d" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_2758bf5d-4533-4add-9e02-2982b7965919" xlink:to="loc_srt_RangeAxis_beeb000a-0e44-43ce-9995-ab812cb2de9d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_0535d903-8fc1-46a6-8ff6-16c38e2e07bd" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_beeb000a-0e44-43ce-9995-ab812cb2de9d" xlink:to="loc_srt_RangeMember_0535d903-8fc1-46a6-8ff6-16c38e2e07bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_5f1c7ec4-4dcb-416d-b2c7-21d61405fd1c" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_0535d903-8fc1-46a6-8ff6-16c38e2e07bd" xlink:to="loc_srt_MinimumMember_5f1c7ec4-4dcb-416d-b2c7-21d61405fd1c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_c547812e-207c-46b0-8a42-7abc9d3e7499" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_0535d903-8fc1-46a6-8ff6-16c38e2e07bd" xlink:to="loc_srt_MaximumMember_c547812e-207c-46b0-8a42-7abc9d3e7499" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_04941e4f-619c-40f0-bad4-40a484f62887" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_2758bf5d-4533-4add-9e02-2982b7965919" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_04941e4f-619c-40f0-bad4-40a484f62887" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_07015ab7-01c3-41fe-889a-14f55a4242bd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_04941e4f-619c-40f0-bad4-40a484f62887" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_07015ab7-01c3-41fe-889a-14f55a4242bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesPayableToBanksMember_4c04f847-aa07-4c5b-8f4d-102930105e4d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NotesPayableToBanksMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_07015ab7-01c3-41fe-889a-14f55a4242bd" xlink:to="loc_us-gaap_NotesPayableToBanksMember_4c04f847-aa07-4c5b-8f4d-102930105e4d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesPayableMember_2394a7b2-ff31-42d6-8314-0da70c3bff70" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesPayableMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_07015ab7-01c3-41fe-889a-14f55a4242bd" xlink:to="loc_us-gaap_DebtSecuritiesPayableMember_2394a7b2-ff31-42d6-8314-0da70c3bff70" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_647ddc06-a42a-464c-87c8-a07d8b9b90b4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_2758bf5d-4533-4add-9e02-2982b7965919" xlink:to="loc_us-gaap_DebtInstrumentAxis_647ddc06-a42a-464c-87c8-a07d8b9b90b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_647ddc06-a42a-464c-87c8-a07d8b9b90b4" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_5ef57bdf-756a-4b3c-bfeb-f59bc65b15f5" xlink:href="amgn-20210930.xsd#amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:to="loc_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_5ef57bdf-756a-4b3c-bfeb-f59bc65b15f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_29964810-e523-4a2e-aae9-3d92dabf26f4" xlink:href="amgn-20210930.xsd#amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:to="loc_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_29964810-e523-4a2e-aae9-3d92dabf26f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember_ddcbfb3a-cb51-4d7d-b659-bad6f71fa986" xlink:href="amgn-20210930.xsd#amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:to="loc_amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember_ddcbfb3a-cb51-4d7d-b659-bad6f71fa986" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointSixFivePercent2028NotesMember_16e0d392-87bf-439b-9407-6e256241777b" xlink:href="amgn-20210930.xsd#amgn_OnePointSixFivePercent2028NotesMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:to="loc_amgn_OnePointSixFivePercent2028NotesMember_16e0d392-87bf-439b-9407-6e256241777b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointZeroPercent2032NotesMemberMember_1f08906d-d837-4326-ba46-543c067e1826" xlink:href="amgn-20210930.xsd#amgn_TwoPointZeroPercent2032NotesMemberMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:to="loc_amgn_TwoPointZeroPercent2032NotesMemberMember_1f08906d-d837-4326-ba46-543c067e1826" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointEightZeroPercent2041NotesMember_6ba8987a-3362-4991-b6f4-878bf8dd9b77" xlink:href="amgn-20210930.xsd#amgn_TwoPointEightZeroPercent2041NotesMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:to="loc_amgn_TwoPointEightZeroPercent2041NotesMember_6ba8987a-3362-4991-b6f4-878bf8dd9b77" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_A300NotesDue20523002052NotesMember_40d682f6-da8c-4494-9aea-924ee006d7ce" xlink:href="amgn-20210930.xsd#amgn_A300NotesDue20523002052NotesMember"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_42357637-0766-4c8d-a511-9a98b7870d85" xlink:to="loc_amgn_A300NotesDue20523002052NotesMember_40d682f6-da8c-4494-9aea-924ee006d7ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_14ec9b2d-647a-49dc-a474-cd0b6d454993" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_2758bf5d-4533-4add-9e02-2982b7965919" xlink:to="loc_us-gaap_DebtInstrumentLineItems_14ec9b2d-647a-49dc-a474-cd0b6d454993" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_cfb0066c-ea21-46f0-aec5-aec2e8535a87" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14ec9b2d-647a-49dc-a474-cd0b6d454993" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_cfb0066c-ea21-46f0-aec5-aec2e8535a87" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_a62baad1-25cf-4d38-82f4-918e0f4d6e95" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14ec9b2d-647a-49dc-a474-cd0b6d454993" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_a62baad1-25cf-4d38-82f4-918e0f4d6e95" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_52963c18-75af-4f13-adf7-0bd33675760d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentFaceAmount"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14ec9b2d-647a-49dc-a474-cd0b6d454993" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_52963c18-75af-4f13-adf7-0bd33675760d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent_7bf27c6e-e0e6-4c01-ae76-c575783cda93" xlink:href="amgn-20210930.xsd#amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14ec9b2d-647a-49dc-a474-cd0b6d454993" xlink:to="loc_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent_7bf27c6e-e0e6-4c01-ae76-c575783cda93" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount_dd841c9f-4552-4b07-b1ee-404186d8e223" xlink:href="amgn-20210930.xsd#amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14ec9b2d-647a-49dc-a474-cd0b6d454993" xlink:to="loc_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount_dd841c9f-4552-4b07-b1ee-404186d8e223" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#FinancingarrangementsinterestrateswapstextualinterimonlyDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_7699fcec-1e5d-4cb9-bcdc-3f8a53de2a0e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_811ff76d-e984-4fa8-a333-c9a4e5091f00" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_7699fcec-1e5d-4cb9-bcdc-3f8a53de2a0e" xlink:to="loc_us-gaap_DebtInstrumentTable_811ff76d-e984-4fa8-a333-c9a4e5091f00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_53651157-20f2-4440-affd-6d8be466b644" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_811ff76d-e984-4fa8-a333-c9a4e5091f00" xlink:to="loc_us-gaap_DebtInstrumentAxis_53651157-20f2-4440-affd-6d8be466b644" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_4c51bcb6-64e5-42a6-8781-fb8575e4cfe7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_53651157-20f2-4440-affd-6d8be466b644" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_4c51bcb6-64e5-42a6-8781-fb8575e4cfe7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointFourFivePercentNotesDue2030Member_ab9b8c1c-d9f3-4cb9-ad0e-79199f838655" xlink:href="amgn-20210930.xsd#amgn_TwoPointFourFivePercentNotesDue2030Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_4c51bcb6-64e5-42a6-8781-fb8575e4cfe7" xlink:to="loc_amgn_TwoPointFourFivePercentNotesDue2030Member_ab9b8c1c-d9f3-4cb9-ad0e-79199f838655" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointThreeZeroPercentNotesDue2031Member_46681be0-a216-41c2-8505-376e983899ab" xlink:href="amgn-20210930.xsd#amgn_TwoPointThreeZeroPercentNotesDue2031Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_4c51bcb6-64e5-42a6-8781-fb8575e4cfe7" xlink:to="loc_amgn_TwoPointThreeZeroPercentNotesDue2031Member_46681be0-a216-41c2-8505-376e983899ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_e42f9ad3-67d9-4667-845d-d9a58d20fbf2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_811ff76d-e984-4fa8-a333-c9a4e5091f00" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_e42f9ad3-67d9-4667-845d-d9a58d20fbf2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_ca583ed8-0cf1-4401-a00c-a1e140a1072d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_e42f9ad3-67d9-4667-845d-d9a58d20fbf2" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_ca583ed8-0cf1-4401-a00c-a1e140a1072d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesPayableToBanksMember_e2b1de45-b351-4858-9681-20579d1b9ad1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NotesPayableToBanksMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_ca583ed8-0cf1-4401-a00c-a1e140a1072d" xlink:to="loc_us-gaap_NotesPayableToBanksMember_e2b1de45-b351-4858-9681-20579d1b9ad1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateAxis_02ec207c-31a0-4891-8fe8-c89c99c8439a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_VariableRateAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_811ff76d-e984-4fa8-a333-c9a4e5091f00" xlink:to="loc_us-gaap_VariableRateAxis_02ec207c-31a0-4891-8fe8-c89c99c8439a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateDomain_2c9bf048-0029-4868-9fb9-004b98cd7860" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_VariableRateDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateAxis_02ec207c-31a0-4891-8fe8-c89c99c8439a" xlink:to="loc_us-gaap_VariableRateDomain_2c9bf048-0029-4868-9fb9-004b98cd7860" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_e85922aa-f9f9-4d2b-8cdd-bda9e9380ee2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LondonInterbankOfferedRateLIBORMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateDomain_2c9bf048-0029-4868-9fb9-004b98cd7860" xlink:to="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_e85922aa-f9f9-4d2b-8cdd-bda9e9380ee2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_5cc63d50-c34c-470a-b086-26683d7a533e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_811ff76d-e984-4fa8-a333-c9a4e5091f00" xlink:to="loc_us-gaap_DebtInstrumentLineItems_5cc63d50-c34c-470a-b086-26683d7a533e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeNotionalAmount_c7aba347-965a-4c29-aa4d-8a01b6a99743" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeNotionalAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5cc63d50-c34c-470a-b086-26683d7a533e" xlink:to="loc_us-gaap_DerivativeNotionalAmount_c7aba347-965a-4c29-aa4d-8a01b6a99743" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_45fa52df-7af0-4814-9c8a-44bdd34b0901" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5cc63d50-c34c-470a-b086-26683d7a533e" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_45fa52df-7af0-4814-9c8a-44bdd34b0901" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeBasisSpreadOnVariableRate_27be2726-f3ef-4319-a9c4-914c7f0c8ee0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeBasisSpreadOnVariableRate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5cc63d50-c34c-470a-b086-26683d7a533e" xlink:to="loc_us-gaap_DerivativeBasisSpreadOnVariableRate_27be2726-f3ef-4319-a9c4-914c7f0c8ee0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/Stockholdersequity" xlink:type="simple" xlink:href="amgn-20210930.xsd#Stockholdersequity"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/Stockholdersequity" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_664c353d-d5ac-444b-b6f2-298902710a01" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_259ab35e-99bc-4656-88d4-32c9fd6ba3c4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_664c353d-d5ac-444b-b6f2-298902710a01" xlink:to="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_259ab35e-99bc-4656-88d4-32c9fd6ba3c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/StockholdersequityTables" xlink:type="simple" xlink:href="amgn-20210930.xsd#StockholdersequityTables"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/StockholdersequityTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_651ae821-a4ba-43ae-8859-3a7631ecb0d2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_StockRepurchaseProgramTableTextBlock_24235947-cec6-4e4e-b2f8-ca9e8a95d6d5" xlink:href="amgn-20210930.xsd#amgn_StockRepurchaseProgramTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_651ae821-a4ba-43ae-8859-3a7631ecb0d2" xlink:to="loc_amgn_StockRepurchaseProgramTableTextBlock_24235947-cec6-4e4e-b2f8-ca9e8a95d6d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock_eae54583-e1dd-43dc-b09a-0b251c203b71" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_651ae821-a4ba-43ae-8859-3a7631ecb0d2" xlink:to="loc_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock_eae54583-e1dd-43dc-b09a-0b251c203b71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock_761a52f9-782b-46fb-8637-0f57d167ed76" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_651ae821-a4ba-43ae-8859-3a7631ecb0d2" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock_761a52f9-782b-46fb-8637-0f57d167ed76" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/StockholdersequityShareRepurchaseProgramDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#StockholdersequityShareRepurchaseProgramDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/StockholdersequityShareRepurchaseProgramDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_fc0420d9-93c6-4c59-b7e0-63ca48fcece4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchasedDuringPeriodShares_8f14aec1-39d5-40ef-b6f6-b7ea731e7cd1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchasedDuringPeriodShares"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_fc0420d9-93c6-4c59-b7e0-63ca48fcece4" xlink:to="loc_us-gaap_StockRepurchasedDuringPeriodShares_8f14aec1-39d5-40ef-b6f6-b7ea731e7cd1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchasedDuringPeriodValue_c9b6d95d-6294-4e0a-983d-3fcf58ab395f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchasedDuringPeriodValue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_fc0420d9-93c6-4c59-b7e0-63ca48fcece4" xlink:to="loc_us-gaap_StockRepurchasedDuringPeriodValue_c9b6d95d-6294-4e0a-983d-3fcf58ab395f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/StockholdersequityDetailsTextualDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#StockholdersequityDetailsTextualDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/StockholdersequityDetailsTextualDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_b092b9bc-98e7-436c-a9b5-d60c3fa4ab4d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_396790c3-9e46-4088-a633-c6ee329431e7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_b092b9bc-98e7-436c-a9b5-d60c3fa4ab4d" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_396790c3-9e46-4088-a633-c6ee329431e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementScenarioAxis_c71a16ec-2e64-4852-aae7-2b86ff2908a8" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_StatementScenarioAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_396790c3-9e46-4088-a633-c6ee329431e7" xlink:to="loc_srt_StatementScenarioAxis_c71a16ec-2e64-4852-aae7-2b86ff2908a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain_ba8ec5b4-734f-4d86-817c-403d5f3dcc8b" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ScenarioUnspecifiedDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_StatementScenarioAxis_c71a16ec-2e64-4852-aae7-2b86ff2908a8" xlink:to="loc_srt_ScenarioUnspecifiedDomain_ba8ec5b4-734f-4d86-817c-403d5f3dcc8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioForecastMember_a6913cf1-787d-4d75-b231-47a0ad3611bc" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ScenarioForecastMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ScenarioUnspecifiedDomain_ba8ec5b4-734f-4d86-817c-403d5f3dcc8b" xlink:to="loc_srt_ScenarioForecastMember_a6913cf1-787d-4d75-b231-47a0ad3611bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_afb0e5d6-3a3c-42ac-9815-8a711ad2ee60" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_396790c3-9e46-4088-a633-c6ee329431e7" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_afb0e5d6-3a3c-42ac-9815-8a711ad2ee60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_72161dcb-131c-4642-97ef-b2e0cba2d86f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_afb0e5d6-3a3c-42ac-9815-8a711ad2ee60" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_72161dcb-131c-4642-97ef-b2e0cba2d86f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_9be879c8-81bc-421d-8222-3f8badef47ec" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_72161dcb-131c-4642-97ef-b2e0cba2d86f" xlink:to="loc_us-gaap_SubsequentEventMember_9be879c8-81bc-421d-8222-3f8badef47ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_6c14c434-ff77-4ca9-a7b7-ee1fe2f10b66" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_396790c3-9e46-4088-a633-c6ee329431e7" xlink:to="loc_us-gaap_ClassOfStockLineItems_6c14c434-ff77-4ca9-a7b7-ee1fe2f10b66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramAuthorizedAmount1_0975e861-5856-40d0-9611-3fb145ca7779" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchaseProgramAuthorizedAmount1"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_6c14c434-ff77-4ca9-a7b7-ee1fe2f10b66" xlink:to="loc_us-gaap_StockRepurchaseProgramAuthorizedAmount1_0975e861-5856-40d0-9611-3fb145ca7779" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_7575b07e-0ad8-4c3e-a3b5-e50427cd609e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_6c14c434-ff77-4ca9-a7b7-ee1fe2f10b66" xlink:to="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_7575b07e-0ad8-4c3e-a3b5-e50427cd609e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockDividendsPerShareDeclared_28f505d0-68f3-4978-b565-6338095b0e5c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockDividendsPerShareDeclared"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_6c14c434-ff77-4ca9-a7b7-ee1fe2f10b66" xlink:to="loc_us-gaap_CommonStockDividendsPerShareDeclared_28f505d0-68f3-4978-b565-6338095b0e5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockDividendsPerShareCashPaid_d7424013-20cf-47e9-bb5d-f646a85e4216" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockDividendsPerShareCashPaid"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_6c14c434-ff77-4ca9-a7b7-ee1fe2f10b66" xlink:to="loc_us-gaap_CommonStockDividendsPerShareCashPaid_d7424013-20cf-47e9-bb5d-f646a85e4216" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#StockholdersequityComponentsofAOCIDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_57169b49-21ad-4645-b91f-901f9c3b8b3c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_5dea8f9f-ab51-4142-a2cd-4216099bc1af" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_57169b49-21ad-4645-b91f-901f9c3b8b3c" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_5dea8f9f-ab51-4142-a2cd-4216099bc1af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_0509bca9-730c-4121-bed8-f581a46f1760" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_5dea8f9f-ab51-4142-a2cd-4216099bc1af" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_0509bca9-730c-4121-bed8-f581a46f1760" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_ba4b5704-c8f2-44e4-9a2a-8f6760b0ae55" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_0509bca9-730c-4121-bed8-f581a46f1760" xlink:to="loc_us-gaap_EquityComponentDomain_ba4b5704-c8f2-44e4-9a2a-8f6760b0ae55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedTranslationAdjustmentMember_dfc0f91f-2c23-4220-b07c-1a7d733e3531" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedTranslationAdjustmentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_ba4b5704-c8f2-44e4-9a2a-8f6760b0ae55" xlink:to="loc_us-gaap_AccumulatedTranslationAdjustmentMember_dfc0f91f-2c23-4220-b07c-1a7d733e3531" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_295f3b53-fbf7-4861-bbd3-77327699aa0b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_ba4b5704-c8f2-44e4-9a2a-8f6760b0ae55" xlink:to="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_295f3b53-fbf7-4861-bbd3-77327699aa0b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember_94542e6a-7583-447f-a331-02d8a322e9d7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_ba4b5704-c8f2-44e4-9a2a-8f6760b0ae55" xlink:to="loc_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember_94542e6a-7583-447f-a331-02d8a322e9d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AccumulatedOtherAdjustmentAttributabletoParentMember_0b737372-05c6-4002-92c3-1ed607d2159b" xlink:href="amgn-20210930.xsd#amgn_AccumulatedOtherAdjustmentAttributabletoParentMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_ba4b5704-c8f2-44e4-9a2a-8f6760b0ae55" xlink:to="loc_amgn_AccumulatedOtherAdjustmentAttributabletoParentMember_0b737372-05c6-4002-92c3-1ed607d2159b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_9e37a4c0-d9bc-4430-aa3f-d638eab0e4b4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_ba4b5704-c8f2-44e4-9a2a-8f6760b0ae55" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_9e37a4c0-d9bc-4430-aa3f-d638eab0e4b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_aab1666c-9699-433f-a160-bfc3c88f997c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_5dea8f9f-ab51-4142-a2cd-4216099bc1af" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_aab1666c-9699-433f-a160-bfc3c88f997c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_aab1666c-9699-433f-a160-bfc3c88f997c" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_28f39203-8577-4de6-98ab-324999f24492" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:to="loc_us-gaap_StockholdersEquity_28f39203-8577-4de6-98ab-324999f24492" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_770a9e72-99d3-44a0-a37a-c08fb40e6eea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_770a9e72-99d3-44a0-a37a-c08fb40e6eea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent_a4c68551-1bea-4331-bd0f-310816049013" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:to="loc_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent_a4c68551-1bea-4331-bd0f-310816049013" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent_46acbf94-42c4-4803-9aa0-4c8e77e54148" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:to="loc_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent_46acbf94-42c4-4803-9aa0-4c8e77e54148" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax_9fe6eb5d-6b48-4765-bb52-484d31f4c770" xlink:href="amgn-20210930.xsd#amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:to="loc_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax_9fe6eb5d-6b48-4765-bb52-484d31f4c770" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1_f77c7279-8c4c-4d57-bcf0-d234cedaae39" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1_f77c7279-8c4c-4d57-bcf0-d234cedaae39" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_0bc6d631-5046-4803-b28c-631a74be16ae" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e68b32bb-11a7-4a7a-8911-93b04f3dc420" xlink:to="loc_us-gaap_StockholdersEquity_0bc6d631-5046-4803-b28c-631a74be16ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#StockholdersequityReclassificationsoutofAOCIDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_64942fc2-2a2e-48ad-9bdc-1720a5ad5530" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_64942fc2-2a2e-48ad-9bdc-1720a5ad5530" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_3a09f67e-087b-4d0e-a36b-e0ad60e5d254" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_3a09f67e-087b-4d0e-a36b-e0ad60e5d254" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_db58e41e-efca-4d2a-a6ba-ffcf3a435791" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_3a09f67e-087b-4d0e-a36b-e0ad60e5d254" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_db58e41e-efca-4d2a-a6ba-ffcf3a435791" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_21d8896d-8224-4454-a375-debe3ae5b6bd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_db58e41e-efca-4d2a-a6ba-ffcf3a435791" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_21d8896d-8224-4454-a375-debe3ae5b6bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_c308d4bf-38f3-4f86-a21a-870e005b9203" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_c308d4bf-38f3-4f86-a21a-870e005b9203" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_7e9df12a-fcee-4e74-a28c-8cabe339c85d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_c308d4bf-38f3-4f86-a21a-870e005b9203" xlink:to="loc_us-gaap_HedgingRelationshipDomain_7e9df12a-fcee-4e74-a28c-8cabe339c85d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgingMember_fef45c42-cd37-4282-b864-9e05f2e86aee" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashFlowHedgingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingRelationshipDomain_7e9df12a-fcee-4e74-a28c-8cabe339c85d" xlink:to="loc_us-gaap_CashFlowHedgingMember_fef45c42-cd37-4282-b864-9e05f2e86aee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_b8528da5-cfa9-437e-b835-87e042aa95a2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_b8528da5-cfa9-437e-b835-87e042aa95a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_cf847c0f-6a68-40cb-8bba-9f4c8c35ebfe" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_b8528da5-cfa9-437e-b835-87e042aa95a2" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_cf847c0f-6a68-40cb-8bba-9f4c8c35ebfe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember_9f2beaef-00d7-4d18-af9c-d9b4529389a7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_cf847c0f-6a68-40cb-8bba-9f4c8c35ebfe" xlink:to="loc_us-gaap_ForeignExchangeContractMember_9f2beaef-00d7-4d18-af9c-d9b4529389a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CrossCurrencySwapContractsMember_46196dca-907c-4137-b9b5-ddb97a5e84f9" xlink:href="amgn-20210930.xsd#amgn_CrossCurrencySwapContractsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_cf847c0f-6a68-40cb-8bba-9f4c8c35ebfe" xlink:to="loc_amgn_CrossCurrencySwapContractsMember_46196dca-907c-4137-b9b5-ddb97a5e84f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_1012c4d2-ba25-41d5-92e0-6f6a17c6fa63" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_1012c4d2-ba25-41d5-92e0-6f6a17c6fa63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_20e6ea85-0264-40fa-a493-3b2fc3a267f7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_1012c4d2-ba25-41d5-92e0-6f6a17c6fa63" xlink:to="loc_us-gaap_EquityComponentDomain_20e6ea85-0264-40fa-a493-3b2fc3a267f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_b7720206-d2de-422d-aeb8-057af5dcab5b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_20e6ea85-0264-40fa-a493-3b2fc3a267f7" xlink:to="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_b7720206-d2de-422d-aeb8-057af5dcab5b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember_f5df7967-ce0c-465f-a420-ba2ab49f0fe1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_20e6ea85-0264-40fa-a493-3b2fc3a267f7" xlink:to="loc_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember_f5df7967-ce0c-465f-a420-ba2ab49f0fe1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_06f0c5c7-f86c-4c7c-8478-92e1665832a4" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:to="loc_srt_ProductOrServiceAxis_06f0c5c7-f86c-4c7c-8478-92e1665832a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_270fd7f0-70af-44a5-8a94-cf4f3e4641a1" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_06f0c5c7-f86c-4c7c-8478-92e1665832a4" xlink:to="loc_srt_ProductsAndServicesDomain_270fd7f0-70af-44a5-8a94-cf4f3e4641a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_252b4dfe-9b5f-458c-83ba-e41735ec4161" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_270fd7f0-70af-44a5-8a94-cf4f3e4641a1" xlink:to="loc_us-gaap_ProductMember_252b4dfe-9b5f-458c-83ba-e41735ec4161" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_027939de-b557-43d6-b829-b1b67fec7546" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_e3f8b861-cb9c-43e9-8fbd-9c190002e2be" xlink:to="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_027939de-b557-43d6-b829-b1b67fec7546" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_98625b91-9f61-4bb2-8ed3-a09f5b94635d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_027939de-b557-43d6-b829-b1b67fec7546" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_98625b91-9f61-4bb2-8ed3-a09f5b94635d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_5e571f75-00c7-4d40-b9ca-3b9ae7edd0d8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NonoperatingIncomeExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_027939de-b557-43d6-b829-b1b67fec7546" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_5e571f75-00c7-4d40-b9ca-3b9ae7edd0d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_03c6c1cc-7623-4468-b7ae-d961322b7533" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_027939de-b557-43d6-b829-b1b67fec7546" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_03c6c1cc-7623-4468-b7ae-d961322b7533" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_f2fbaff4-0af2-49ac-a059-cf7f367a1140" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_027939de-b557-43d6-b829-b1b67fec7546" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_f2fbaff4-0af2-49ac-a059-cf7f367a1140" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_349a71e8-11d0-43ca-9962-8f4ebae7f364" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_027939de-b557-43d6-b829-b1b67fec7546" xlink:to="loc_us-gaap_NetIncomeLoss_349a71e8-11d0-43ca-9962-8f4ebae7f364" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/Fairvaluemeasurement" xlink:type="simple" xlink:href="amgn-20210930.xsd#Fairvaluemeasurement"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/Fairvaluemeasurement" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_c0b8fc65-d99a-470e-a62f-4048098b9d34" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresTextBlock_bd3dcd79-43c6-45f7-bc6d-4cbe6c761db6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_c0b8fc65-d99a-470e-a62f-4048098b9d34" xlink:to="loc_us-gaap_FairValueDisclosuresTextBlock_bd3dcd79-43c6-45f7-bc6d-4cbe6c761db6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/FairvaluemeasurementTables" xlink:type="simple" xlink:href="amgn-20210930.xsd#FairvaluemeasurementTables"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/FairvaluemeasurementTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_22f41e34-fbac-45a0-b85d-803e8678e15e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_f8eef8d1-8d85-40a9-96f9-27aa44556167" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_22f41e34-fbac-45a0-b85d-803e8678e15e" xlink:to="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_f8eef8d1-8d85-40a9-96f9-27aa44556167" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/FairvaluemeasurementDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#FairvaluemeasurementDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/FairvaluemeasurementDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_15b1c86d-9b11-4674-bfd9-a993a0dd70df" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_3254f57a-09f9-45e1-a40b-f0220870d0aa" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_15b1c86d-9b11-4674-bfd9-a993a0dd70df" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_3254f57a-09f9-45e1-a40b-f0220870d0aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_4cb3cd75-3ae7-4855-86e9-799f48cee935" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_3254f57a-09f9-45e1-a40b-f0220870d0aa" xlink:to="loc_us-gaap_FinancialInstrumentAxis_4cb3cd75-3ae7-4855-86e9-799f48cee935" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_4cb3cd75-3ae7-4855-86e9-799f48cee935" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasurySecuritiesMember_d12916a4-32c8-4b27-9e7c-b6e73bad384d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USTreasurySecuritiesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_us-gaap_USTreasurySecuritiesMember_d12916a4-32c8-4b27-9e7c-b6e73bad384d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasuryBillSecuritiesMember_a6b4eff2-118d-492b-a7d8-763edc26f143" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USTreasuryBillSecuritiesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_us-gaap_USTreasuryBillSecuritiesMember_a6b4eff2-118d-492b-a7d8-763edc26f143" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_25605224-5735-4b1f-ac8e-cd255ab4bea2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USGovernmentAgenciesDebtSecuritiesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_25605224-5735-4b1f-ac8e-cd255ab4bea2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_4b6b5d2b-08f7-45dc-af86-02f7ae4aaf1a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignGovernmentDebtSecuritiesMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_4b6b5d2b-08f7-45dc-af86-02f7ae4aaf1a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesFinancialMember_54b7aa0d-46e8-4552-919f-49804ce3a81a" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesFinancialMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_amgn_CorporateDebtSecuritiesFinancialMember_54b7aa0d-46e8-4552-919f-49804ce3a81a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesIndustrialMember_643cf216-2ed1-45e3-8860-977e334d1cb3" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesIndustrialMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_amgn_CorporateDebtSecuritiesIndustrialMember_643cf216-2ed1-45e3-8860-977e334d1cb3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CorporateDebtSecuritiesOtherMember_677a4215-ef85-43a7-9404-50168cac97da" xlink:href="amgn-20210930.xsd#amgn_CorporateDebtSecuritiesOtherMember"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_amgn_CorporateDebtSecuritiesOtherMember_677a4215-ef85-43a7-9404-50168cac97da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_b5f4b33f-a8e7-4e13-b1b1-e3dfea1f5e32" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResidentialMortgageBackedSecuritiesMember"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_b5f4b33f-a8e7-4e13-b1b1-e3dfea1f5e32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetBackedSecuritiesMember_d3dd6030-f248-4e86-b7e0-50d462158d5d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetBackedSecuritiesMember"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_us-gaap_AssetBackedSecuritiesMember_d3dd6030-f248-4e86-b7e0-50d462158d5d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MoneyMarketFundsMember_49acab65-c1ce-4ea9-9f40-d476116a068a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MoneyMarketFundsMember"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_us-gaap_MoneyMarketFundsMember_49acab65-c1ce-4ea9-9f40-d476116a068a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherShortTermInterestBearingSecuritiesMember_cd0da086-b517-4e96-aab4-9206aa970345" xlink:href="amgn-20210930.xsd#amgn_OtherShortTermInterestBearingSecuritiesMember"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_7a8ea2c1-4dd9-460f-8109-4933b8e091df" xlink:to="loc_amgn_OtherShortTermInterestBearingSecuritiesMember_cd0da086-b517-4e96-aab4-9206aa970345" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_334d60c9-d6a6-4bfb-9e82-1b3c0cbeca97" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_3254f57a-09f9-45e1-a40b-f0220870d0aa" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_334d60c9-d6a6-4bfb-9e82-1b3c0cbeca97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_22dc9423-5348-4537-a845-93c64fd9def0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_334d60c9-d6a6-4bfb-9e82-1b3c0cbeca97" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_22dc9423-5348-4537-a845-93c64fd9def0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_87a3e4ca-6bf1-492d-8507-5694055520c3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_22dc9423-5348-4537-a845-93c64fd9def0" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_87a3e4ca-6bf1-492d-8507-5694055520c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_0065aec3-12c2-4250-81eb-5c87aeb68831" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel2Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_22dc9423-5348-4537-a845-93c64fd9def0" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_0065aec3-12c2-4250-81eb-5c87aeb68831" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_e594a643-fee3-494e-a7c8-fb930814ba3d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel3Member"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_22dc9423-5348-4537-a845-93c64fd9def0" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_e594a643-fee3-494e-a7c8-fb930814ba3d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_b8442367-6cf0-4c39-92d8-fcd0088ff1d6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_3254f57a-09f9-45e1-a40b-f0220870d0aa" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_b8442367-6cf0-4c39-92d8-fcd0088ff1d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_59922e29-ae1f-4725-b2c5-935f33a8bc09" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_b8442367-6cf0-4c39-92d8-fcd0088ff1d6" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_59922e29-ae1f-4725-b2c5-935f33a8bc09" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember_732a4583-c3dc-4821-a3cc-f0a1c8f31699" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_59922e29-ae1f-4725-b2c5-935f33a8bc09" xlink:to="loc_us-gaap_ForeignExchangeContractMember_732a4583-c3dc-4821-a3cc-f0a1c8f31699" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CrossCurrencySwapContractsMember_e07e66c8-6be5-4e29-bc7e-20ce9f200a64" xlink:href="amgn-20210930.xsd#amgn_CrossCurrencySwapContractsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_59922e29-ae1f-4725-b2c5-935f33a8bc09" xlink:to="loc_amgn_CrossCurrencySwapContractsMember_e07e66c8-6be5-4e29-bc7e-20ce9f200a64" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember_b80f715c-593b-4780-83ea-bcd5394d384e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateSwapMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_59922e29-ae1f-4725-b2c5-935f33a8bc09" xlink:to="loc_us-gaap_InterestRateSwapMember_b80f715c-593b-4780-83ea-bcd5394d384e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_993b119c-91a8-451b-8405-c82412e5e4d4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_3254f57a-09f9-45e1-a40b-f0220870d0aa" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_993b119c-91a8-451b-8405-c82412e5e4d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosureAbstract_4830e02e-0363-45eb-af4d-736e64d48694" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsFairValueDisclosureAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_993b119c-91a8-451b-8405-c82412e5e4d4" xlink:to="loc_us-gaap_AssetsFairValueDisclosureAbstract_4830e02e-0363-45eb-af4d-736e64d48694" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_d59bf30f-5b51-45d6-b39c-d0e188f57705" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_4830e02e-0363-45eb-af4d-736e64d48694" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_d59bf30f-5b51-45d6-b39c-d0e188f57705" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNi_df8d9006-dd86-470f-93f0-7138730b1af5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquitySecuritiesFvNi"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_4830e02e-0363-45eb-af4d-736e64d48694" xlink:to="loc_us-gaap_EquitySecuritiesFvNi_df8d9006-dd86-470f-93f0-7138730b1af5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DerivativeAssetsFairValueDisclosureAbstract_ef24e271-d3af-43a5-a875-2921a9b0c9bc" xlink:href="amgn-20210930.xsd#amgn_DerivativeAssetsFairValueDisclosureAbstract"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_4830e02e-0363-45eb-af4d-736e64d48694" xlink:to="loc_amgn_DerivativeAssetsFairValueDisclosureAbstract_ef24e271-d3af-43a5-a875-2921a9b0c9bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure_af03c229-6e08-41a7-8c56-ef07b310cfff" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignCurrencyContractAssetFairValueDisclosure"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_DerivativeAssetsFairValueDisclosureAbstract_ef24e271-d3af-43a5-a875-2921a9b0c9bc" xlink:to="loc_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure_af03c229-6e08-41a7-8c56-ef07b310cfff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateFairValueHedgeAssetAtFairValue_84cdbfe6-061f-4b6e-8d0a-2bb6c0a706dc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateFairValueHedgeAssetAtFairValue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_DerivativeAssetsFairValueDisclosureAbstract_ef24e271-d3af-43a5-a875-2921a9b0c9bc" xlink:to="loc_us-gaap_InterestRateFairValueHedgeAssetAtFairValue_84cdbfe6-061f-4b6e-8d0a-2bb6c0a706dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_138b17bf-6ece-44b0-9526-e392176ee5af" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_4830e02e-0363-45eb-af4d-736e64d48694" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_138b17bf-6ece-44b0-9526-e392176ee5af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_77889367-b105-43ff-9ee2-60290e1da71d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosureAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_993b119c-91a8-451b-8405-c82412e5e4d4" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_77889367-b105-43ff-9ee2-60290e1da71d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_0174f8d7-974b-492c-95e1-67bdeef8ba62" xlink:href="amgn-20210930.xsd#amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_77889367-b105-43ff-9ee2-60290e1da71d" xlink:to="loc_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_0174f8d7-974b-492c-95e1-67bdeef8ba62" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_3683a701-add8-4ea7-a946-51d2efc5ed52" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_0174f8d7-974b-492c-95e1-67bdeef8ba62" xlink:to="loc_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_3683a701-add8-4ea7-a946-51d2efc5ed52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_6c701fa2-efc3-4b7f-8963-6ee08a13d189" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_0174f8d7-974b-492c-95e1-67bdeef8ba62" xlink:to="loc_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_6c701fa2-efc3-4b7f-8963-6ee08a13d189" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_5cb62aa4-8ffd-4e4e-b5ec-5fc7e79e430c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_0174f8d7-974b-492c-95e1-67bdeef8ba62" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_5cb62aa4-8ffd-4e4e-b5ec-5fc7e79e430c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_fd298085-4471-408a-acb6-45c6bbfdcaea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_77889367-b105-43ff-9ee2-60290e1da71d" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosure_fd298085-4471-408a-acb6-45c6bbfdcaea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/FairvaluemeasurementDetailsTextual" xlink:type="simple" xlink:href="amgn-20210930.xsd#FairvaluemeasurementDetailsTextual"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/FairvaluemeasurementDetailsTextual" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_b6893caa-db15-4598-8b2a-674b43698740" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge_25cfecb8-1a0f-4cb2-a874-247e9961c9f2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_b6893caa-db15-4598-8b2a-674b43698740" xlink:to="loc_us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge_25cfecb8-1a0f-4cb2-a874-247e9961c9f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesPayableFairValueDisclosure_d45d3add-e1b3-432c-890d-cc72c731a121" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NotesPayableFairValueDisclosure"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_b6893caa-db15-4598-8b2a-674b43698740" xlink:to="loc_us-gaap_NotesPayableFairValueDisclosure_d45d3add-e1b3-432c-890d-cc72c731a121" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_68cc21c4-7abe-4b01-979d-33dac199a3d1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebt"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_b6893caa-db15-4598-8b2a-674b43698740" xlink:to="loc_us-gaap_LongTermDebt_68cc21c4-7abe-4b01-979d-33dac199a3d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/SubsequentEvents" xlink:type="simple" xlink:href="amgn-20210930.xsd#SubsequentEvents"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/SubsequentEvents" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_96371bac-45fa-4a22-9e0b-f56d45a8b813" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventsAbstract"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/SubsequentEventsTables" xlink:type="simple" xlink:href="amgn-20210930.xsd#SubsequentEventsTables"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/SubsequentEventsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_634fe531-448d-48cd-9e8e-98e8b56364ea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventsAbstract"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/SubsequentEventsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#SubsequentEventsDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/SubsequentEventsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_230d8000-8561-4888-a5b6-6036101724cb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventsAbstract"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/Derivativeinstruments" xlink:type="simple" xlink:href="amgn-20210930.xsd#Derivativeinstruments"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/Derivativeinstruments" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_d465e082-a2a8-444b-9d65-ebf211352085" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock_1ea2b890-8339-4079-99af-746f524440f3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_d465e082-a2a8-444b-9d65-ebf211352085" xlink:to="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock_1ea2b890-8339-4079-99af-746f524440f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/DerivativeinstrumentsTables" xlink:type="simple" xlink:href="amgn-20210930.xsd#DerivativeinstrumentsTables"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/DerivativeinstrumentsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_a62a330f-4079-4f73-bbd2-3f942c16f87d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock_78efec25-d53b-4448-b1ac-cbc89288e159" xlink:href="amgn-20210930.xsd#amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_a62a330f-4079-4f73-bbd2-3f942c16f87d" xlink:to="loc_amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock_78efec25-d53b-4448-b1ac-cbc89288e159" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock_e89587c0-73bc-4620-9801-f68f97cb8aca" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_a62a330f-4079-4f73-bbd2-3f942c16f87d" xlink:to="loc_us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock_e89587c0-73bc-4620-9801-f68f97cb8aca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock_4ddace64-2e25-4259-89f9-6ea68ac311b9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_a62a330f-4079-4f73-bbd2-3f942c16f87d" xlink:to="loc_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock_4ddace64-2e25-4259-89f9-6ea68ac311b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock_f8d84112-f564-47b1-b8c9-7df25437c3f6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_a62a330f-4079-4f73-bbd2-3f942c16f87d" xlink:to="loc_us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock_f8d84112-f564-47b1-b8c9-7df25437c3f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock_59981238-0ced-4103-8c06-ac1e0d2da7a8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_a62a330f-4079-4f73-bbd2-3f942c16f87d" xlink:to="loc_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock_59981238-0ced-4103-8c06-ac1e0d2da7a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual" xlink:type="simple" xlink:href="amgn-20210930.xsd#DerivativeinstrumentsDetailsTextual"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_c08bdd93-55b6-4dcd-86f2-aebd5f546db7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_c08bdd93-55b6-4dcd-86f2-aebd5f546db7" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByLiabilityClassAxis_59cace25-f199-411f-ace0-ae576f13b756" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByLiabilityClassAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_us-gaap_FairValueByLiabilityClassAxis_59cace25-f199-411f-ace0-ae576f13b756" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_0ce589c9-5a87-4e64-afe8-f03d46a37b1a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_59cace25-f199-411f-ace0-ae576f13b756" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_0ce589c9-5a87-4e64-afe8-f03d46a37b1a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMember_fb6f82b2-1a2a-4eb2-a33b-70e810a50da3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_0ce589c9-5a87-4e64-afe8-f03d46a37b1a" xlink:to="loc_us-gaap_LongTermDebtMember_fb6f82b2-1a2a-4eb2-a33b-70e810a50da3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_f7f201c5-af17-4a1a-9d78-35e9ce28230d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_f7f201c5-af17-4a1a-9d78-35e9ce28230d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_fde69c5c-bb5c-4b28-92f3-010d52d737f3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_f7f201c5-af17-4a1a-9d78-35e9ce28230d" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_fde69c5c-bb5c-4b28-92f3-010d52d737f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationAxis_b4addb1e-4814-45d7-b1b9-551f64ce45e8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingDesignationAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_us-gaap_HedgingDesignationAxis_b4addb1e-4814-45d7-b1b9-551f64ce45e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_06b6b9f8-9198-422a-8b1b-2b9658be5a07" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingDesignationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingDesignationAxis_b4addb1e-4814-45d7-b1b9-551f64ce45e8" xlink:to="loc_us-gaap_HedgingDesignationDomain_06b6b9f8-9198-422a-8b1b-2b9658be5a07" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_193a62b7-3e8a-4c29-93c9-efda5594937b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingDesignationDomain_06b6b9f8-9198-422a-8b1b-2b9658be5a07" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_193a62b7-3e8a-4c29-93c9-efda5594937b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NondesignatedMember_010057d7-37d2-4b35-868e-366b110b4b37" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NondesignatedMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingDesignationDomain_06b6b9f8-9198-422a-8b1b-2b9658be5a07" xlink:to="loc_us-gaap_NondesignatedMember_010057d7-37d2-4b35-868e-366b110b4b37" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_82b3ea10-c79f-462b-b31c-942dc0118f93" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_82b3ea10-c79f-462b-b31c-942dc0118f93" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_6933ab0e-0593-4d7f-a94f-3595444966be" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_82b3ea10-c79f-462b-b31c-942dc0118f93" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_6933ab0e-0593-4d7f-a94f-3595444966be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForwardContractsMember_62f10251-4a03-4584-a1b6-4a5f7215a3fb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForwardContractsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_6933ab0e-0593-4d7f-a94f-3595444966be" xlink:to="loc_us-gaap_ForwardContractsMember_62f10251-4a03-4584-a1b6-4a5f7215a3fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ForeignCurrencyAndCrossCurrencySwapsMember_7bce1572-5590-46a2-8693-b5430e4aaabb" xlink:href="amgn-20210930.xsd#amgn_ForeignCurrencyAndCrossCurrencySwapsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_6933ab0e-0593-4d7f-a94f-3595444966be" xlink:to="loc_amgn_ForeignCurrencyAndCrossCurrencySwapsMember_7bce1572-5590-46a2-8693-b5430e4aaabb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember_9ffc129d-15a2-4bd2-a5c5-a1139cff4359" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateSwapMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_6933ab0e-0593-4d7f-a94f-3595444966be" xlink:to="loc_us-gaap_InterestRateSwapMember_9ffc129d-15a2-4bd2-a5c5-a1139cff4359" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_d7ee97ed-bdf7-40d1-a074-1ad2c59a8120" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_us-gaap_DebtInstrumentAxis_d7ee97ed-bdf7-40d1-a074-1ad2c59a8120" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_03305bfc-0692-443d-b672-cb7433b44fea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_d7ee97ed-bdf7-40d1-a074-1ad2c59a8120" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_03305bfc-0692-443d-b672-cb7433b44fea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointFourFivePercentNotesDue2030Member_c71f6bd2-2351-48d7-8892-66a568100b53" xlink:href="amgn-20210930.xsd#amgn_TwoPointFourFivePercentNotesDue2030Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_03305bfc-0692-443d-b672-cb7433b44fea" xlink:to="loc_amgn_TwoPointFourFivePercentNotesDue2030Member_c71f6bd2-2351-48d7-8892-66a568100b53" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPointThreeZeroPercentNotesDue2031Member_6f05dad8-2c00-4ee5-b52f-9067a4b742de" xlink:href="amgn-20210930.xsd#amgn_TwoPointThreeZeroPercentNotesDue2031Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_03305bfc-0692-443d-b672-cb7433b44fea" xlink:to="loc_amgn_TwoPointThreeZeroPercentNotesDue2031Member_6f05dad8-2c00-4ee5-b52f-9067a4b742de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_d262bd13-a9dc-4f5d-a9dc-7fd3887bef81" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_d262bd13-a9dc-4f5d-a9dc-7fd3887bef81" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_d40c83a0-e90c-4c7f-a29f-c2005ac49ff9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_d262bd13-a9dc-4f5d-a9dc-7fd3887bef81" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_d40c83a0-e90c-4c7f-a29f-c2005ac49ff9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesPayableToBanksMember_46f4269d-723b-4230-8e60-6278a4d7b959" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NotesPayableToBanksMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_d40c83a0-e90c-4c7f-a29f-c2005ac49ff9" xlink:to="loc_us-gaap_NotesPayableToBanksMember_46f4269d-723b-4230-8e60-6278a4d7b959" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DerivativeInstrumentNameAxis_2cfded0a-8769-4748-805d-e23d6985a8f3" xlink:href="amgn-20210930.xsd#amgn_DerivativeInstrumentNameAxis"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_amgn_DerivativeInstrumentNameAxis_2cfded0a-8769-4748-805d-e23d6985a8f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_DerivativeInstrumentNameDomain_69b5d704-fa03-459d-b1a0-996f6dc75e8f" xlink:href="amgn-20210930.xsd#amgn_DerivativeInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_DerivativeInstrumentNameAxis_2cfded0a-8769-4748-805d-e23d6985a8f3" xlink:to="loc_amgn_DerivativeInstrumentNameDomain_69b5d704-fa03-459d-b1a0-996f6dc75e8f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_A2030And2021NoteHedgesMember_3abbee80-d5f9-4861-a648-33e09dea94c9" xlink:href="amgn-20210930.xsd#amgn_A2030And2021NoteHedgesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_DerivativeInstrumentNameDomain_69b5d704-fa03-459d-b1a0-996f6dc75e8f" xlink:to="loc_amgn_A2030And2021NoteHedgesMember_3abbee80-d5f9-4861-a648-33e09dea94c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_90a36aee-d650-40db-bcd0-33dcc1126b92" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_915e5a2d-f61d-4ff8-b312-3d71b599938d" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_90a36aee-d650-40db-bcd0-33dcc1126b92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeNotionalAmount_36301aa5-ebd8-4b1d-9e88-6220489d7e51" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeNotionalAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_90a36aee-d650-40db-bcd0-33dcc1126b92" xlink:to="loc_us-gaap_DerivativeNotionalAmount_36301aa5-ebd8-4b1d-9e88-6220489d7e51" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months_5c59b9ea-c34b-4362-b723-431ebb1066ba" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_90a36aee-d650-40db-bcd0-33dcc1126b92" xlink:to="loc_us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months_5c59b9ea-c34b-4362-b723-431ebb1066ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_348c50ab-17e6-4ad2-be5c-5ce8a457a669" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_90a36aee-d650-40db-bcd0-33dcc1126b92" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_348c50ab-17e6-4ad2-be5c-5ce8a457a669" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#DerivativeinstrumentsCrosscurrencySwapsDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_c0fdc63e-5c34-457a-98bf-e811436daa82" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeTable_48afce5a-317c-4a9d-bf25-5c0e1172bf7a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_c0fdc63e-5c34-457a-98bf-e811436daa82" xlink:to="loc_us-gaap_DerivativeTable_48afce5a-317c-4a9d-bf25-5c0e1172bf7a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_6d991916-1c40-4ca4-8f61-acf83c79574d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeTable_48afce5a-317c-4a9d-bf25-5c0e1172bf7a" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_6d991916-1c40-4ca4-8f61-acf83c79574d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_31e6437a-8104-41bf-8782-d7c5368b0063" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_6d991916-1c40-4ca4-8f61-acf83c79574d" xlink:to="loc_us-gaap_HedgingRelationshipDomain_31e6437a-8104-41bf-8782-d7c5368b0063" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgingMember_a65ac1ac-554e-47d2-bec3-823af633ec6b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashFlowHedgingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingRelationshipDomain_31e6437a-8104-41bf-8782-d7c5368b0063" xlink:to="loc_us-gaap_CashFlowHedgingMember_a65ac1ac-554e-47d2-bec3-823af633ec6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_a9154491-9415-4ea6-8c7e-c513dfbfdda9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeTable_48afce5a-317c-4a9d-bf25-5c0e1172bf7a" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_a9154491-9415-4ea6-8c7e-c513dfbfdda9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_01e8780b-e137-45be-880c-b8b5f3bc4f02" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_a9154491-9415-4ea6-8c7e-c513dfbfdda9" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_01e8780b-e137-45be-880c-b8b5f3bc4f02" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CrossCurrencySwapContractsMember_88baae03-4fe2-43c8-80d6-83bf2776fc71" xlink:href="amgn-20210930.xsd#amgn_CrossCurrencySwapContractsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_01e8780b-e137-45be-880c-b8b5f3bc4f02" xlink:to="loc_amgn_CrossCurrencySwapContractsMember_88baae03-4fe2-43c8-80d6-83bf2776fc71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CurrencyAxis_9a9afd81-9d8e-4f0b-820b-024495974319" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CurrencyAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeTable_48afce5a-317c-4a9d-bf25-5c0e1172bf7a" xlink:to="loc_srt_CurrencyAxis_9a9afd81-9d8e-4f0b-820b-024495974319" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_currency_AllCurrenciesDomain_6604c395-3883-4863-a13d-8fc070f326fc" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_AllCurrenciesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CurrencyAxis_9a9afd81-9d8e-4f0b-820b-024495974319" xlink:to="loc_currency_AllCurrenciesDomain_6604c395-3883-4863-a13d-8fc070f326fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_currency_EUR_5882394e-259c-46e7-bb03-979a9e8e104d" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_EUR"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_currency_AllCurrenciesDomain_6604c395-3883-4863-a13d-8fc070f326fc" xlink:to="loc_currency_EUR_5882394e-259c-46e7-bb03-979a9e8e104d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_currency_CHF_e6cb1acc-abfa-4591-8537-c998ebf5e751" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_CHF"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_currency_AllCurrenciesDomain_6604c395-3883-4863-a13d-8fc070f326fc" xlink:to="loc_currency_CHF_e6cb1acc-abfa-4591-8537-c998ebf5e751" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_currency_GBP_4f2066fa-3908-40ac-8242-74cd2e7ea948" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_GBP"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_currency_AllCurrenciesDomain_6604c395-3883-4863-a13d-8fc070f326fc" xlink:to="loc_currency_GBP_4f2066fa-3908-40ac-8242-74cd2e7ea948" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_currency_USD_dea145be-87da-485a-a0e9-13237c465efd" xlink:href="https://xbrl.sec.gov/currency/2021/currency-2021.xsd#currency_USD"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_currency_AllCurrenciesDomain_6604c395-3883-4863-a13d-8fc070f326fc" xlink:to="loc_currency_USD_dea145be-87da-485a-a0e9-13237c465efd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_3a686517-6a11-4b1d-a173-0127d151369b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeTable_48afce5a-317c-4a9d-bf25-5c0e1172bf7a" xlink:to="loc_us-gaap_DebtInstrumentAxis_3a686517-6a11-4b1d-a173-0127d151369b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_37d0f2e6-24a9-4a60-b62e-7b37bfe70bff" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_3a686517-6a11-4b1d-a173-0127d151369b" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_37d0f2e6-24a9-4a60-b62e-7b37bfe70bff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember_ea45f2d5-b9f1-49b1-913a-04370b7041a6" xlink:href="amgn-20210930.xsd#amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_37d0f2e6-24a9-4a60-b62e-7b37bfe70bff" xlink:to="loc_amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember_ea45f2d5-b9f1-49b1-913a-04370b7041a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_430a6a3a-9bd8-4361-86fa-41905f84cc56" xlink:href="amgn-20210930.xsd#amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_37d0f2e6-24a9-4a60-b62e-7b37bfe70bff" xlink:to="loc_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_430a6a3a-9bd8-4361-86fa-41905f84cc56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_b7952098-b8bb-495d-bda1-415184f37b0e" xlink:href="amgn-20210930.xsd#amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_37d0f2e6-24a9-4a60-b62e-7b37bfe70bff" xlink:to="loc_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_b7952098-b8bb-495d-bda1-415184f37b0e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_5dcead17-6c34-43c5-912e-4d2547712ad4" xlink:href="amgn-20210930.xsd#amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_37d0f2e6-24a9-4a60-b62e-7b37bfe70bff" xlink:to="loc_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_5dcead17-6c34-43c5-912e-4d2547712ad4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FourPercentPoundSterlingNotesDue2029Member_aff5c601-d259-4016-9b7c-ee42d7c38177" xlink:href="amgn-20210930.xsd#amgn_FourPercentPoundSterlingNotesDue2029Member"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_37d0f2e6-24a9-4a60-b62e-7b37bfe70bff" xlink:to="loc_amgn_FourPercentPoundSterlingNotesDue2029Member_aff5c601-d259-4016-9b7c-ee42d7c38177" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLineItems_c4aa70e3-a36e-4ba6-84ba-1e2ea8853f2a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeLineItems"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeTable_48afce5a-317c-4a9d-bf25-5c0e1172bf7a" xlink:to="loc_us-gaap_DerivativeLineItems_c4aa70e3-a36e-4ba6-84ba-1e2ea8853f2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeNotionalAmount_b0a92eb0-56cd-483d-a6de-c76925394ccd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeNotionalAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLineItems_c4aa70e3-a36e-4ba6-84ba-1e2ea8853f2a" xlink:to="loc_us-gaap_DerivativeNotionalAmount_b0a92eb0-56cd-483d-a6de-c76925394ccd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFixedInterestRate_390e7eeb-d06b-4a4a-b142-6b36d378aa58" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeFixedInterestRate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLineItems_c4aa70e3-a36e-4ba6-84ba-1e2ea8853f2a" xlink:to="loc_us-gaap_DerivativeFixedInterestRate_390e7eeb-d06b-4a4a-b142-6b36d378aa58" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_afd36c2b-5d39-4c04-8a88-2672f16326b2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_87f75a0f-62a2-4e0e-934a-b870cc8dda90" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_afd36c2b-5d39-4c04-8a88-2672f16326b2" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_87f75a0f-62a2-4e0e-934a-b870cc8dda90" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_d8394c2d-d301-4bc5-9382-13335df93c64" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_87f75a0f-62a2-4e0e-934a-b870cc8dda90" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_d8394c2d-d301-4bc5-9382-13335df93c64" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_0fbc60ea-6a66-44de-a447-6fe59328d6ee" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_d8394c2d-d301-4bc5-9382-13335df93c64" xlink:to="loc_us-gaap_HedgingRelationshipDomain_0fbc60ea-6a66-44de-a447-6fe59328d6ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgingMember_67f297f0-b68f-4270-9f8b-14d061905c0a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashFlowHedgingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingRelationshipDomain_0fbc60ea-6a66-44de-a447-6fe59328d6ee" xlink:to="loc_us-gaap_CashFlowHedgingMember_67f297f0-b68f-4270-9f8b-14d061905c0a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_5041c7f2-c36c-489d-9c2a-d347ddb1c3dd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_87f75a0f-62a2-4e0e-934a-b870cc8dda90" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_5041c7f2-c36c-489d-9c2a-d347ddb1c3dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_f0fac6f9-6308-47c4-a3b3-6d5602ba2a2e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_5041c7f2-c36c-489d-9c2a-d347ddb1c3dd" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_f0fac6f9-6308-47c4-a3b3-6d5602ba2a2e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember_b08f3727-0587-416e-bc08-d005fa577989" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_f0fac6f9-6308-47c4-a3b3-6d5602ba2a2e" xlink:to="loc_us-gaap_ForeignExchangeContractMember_b08f3727-0587-416e-bc08-d005fa577989" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CrossCurrencySwapContractsMember_e9a6585f-b21f-4f9a-970d-4837330c1e2a" xlink:href="amgn-20210930.xsd#amgn_CrossCurrencySwapContractsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_f0fac6f9-6308-47c4-a3b3-6d5602ba2a2e" xlink:to="loc_amgn_CrossCurrencySwapContractsMember_e9a6585f-b21f-4f9a-970d-4837330c1e2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_dd5d8737-d3d9-4e6e-ad15-c6b5261b90b6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_87f75a0f-62a2-4e0e-934a-b870cc8dda90" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_dd5d8737-d3d9-4e6e-ad15-c6b5261b90b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax_7b45aea6-0939-4404-a318-64bf01339642" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_dd5d8737-d3d9-4e6e-ad15-c6b5261b90b6" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax_7b45aea6-0939-4404-a318-64bf01339642" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_1a149bed-4d7a-4299-80c0-524d485df111" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeTable_4027a53b-b0b1-48e3-ba49-ff46a745e38b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_1a149bed-4d7a-4299-80c0-524d485df111" xlink:to="loc_us-gaap_DerivativeTable_4027a53b-b0b1-48e3-ba49-ff46a745e38b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByLiabilityClassAxis_a8082dc9-42ca-428a-9996-823389212acb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByLiabilityClassAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeTable_4027a53b-b0b1-48e3-ba49-ff46a745e38b" xlink:to="loc_us-gaap_FairValueByLiabilityClassAxis_a8082dc9-42ca-428a-9996-823389212acb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_4e6520e4-2158-49ba-a6c6-417c49b7d47c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_a8082dc9-42ca-428a-9996-823389212acb" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_4e6520e4-2158-49ba-a6c6-417c49b7d47c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LongTermDebtCurrentMaturitiesMember_9025b259-e72f-43fb-a0c5-b22c8375b4a9" xlink:href="amgn-20210930.xsd#amgn_LongTermDebtCurrentMaturitiesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_4e6520e4-2158-49ba-a6c6-417c49b7d47c" xlink:to="loc_amgn_LongTermDebtCurrentMaturitiesMember_9025b259-e72f-43fb-a0c5-b22c8375b4a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMember_78ac143b-da7a-466d-a188-4d32ab91753f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_4e6520e4-2158-49ba-a6c6-417c49b7d47c" xlink:to="loc_us-gaap_LongTermDebtMember_78ac143b-da7a-466d-a188-4d32ab91753f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLineItems_d911e339-e924-473f-9115-ccae93bbe2df" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeTable_4027a53b-b0b1-48e3-ba49-ff46a745e38b" xlink:to="loc_us-gaap_DerivativeLineItems_d911e339-e924-473f-9115-ccae93bbe2df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgedLiabilityFairValueHedge_1af59a8f-9c83-4072-877b-fa061deb157b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgedLiabilityFairValueHedge"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLineItems_d911e339-e924-473f-9115-ccae93bbe2df" xlink:to="loc_us-gaap_HedgedLiabilityFairValueHedge_1af59a8f-9c83-4072-877b-fa061deb157b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease_5dbaf4c5-0797-4b2d-b54b-5376de6fe158" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLineItems_d911e339-e924-473f-9115-ccae93bbe2df" xlink:to="loc_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease_5dbaf4c5-0797-4b2d-b54b-5376de6fe158" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_HedgedLiabilityDiscontinuedFairValueHedge_eabb5722-647d-4b19-b116-cb6d812d6a6b" xlink:href="amgn-20210930.xsd#amgn_HedgedLiabilityDiscontinuedFairValueHedge"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLineItems_d911e339-e924-473f-9115-ccae93bbe2df" xlink:to="loc_amgn_HedgedLiabilityDiscontinuedFairValueHedge_eabb5722-647d-4b19-b116-cb6d812d6a6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease_63ca20cc-13ba-4906-9289-f3d340901667" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLineItems_d911e339-e924-473f-9115-ccae93bbe2df" xlink:to="loc_us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease_63ca20cc-13ba-4906-9289-f3d340901667" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_88114059-2ddb-48a7-a03c-909489fa51b6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_958b2362-e40e-4855-9ef7-be526c60cae3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_88114059-2ddb-48a7-a03c-909489fa51b6" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_958b2362-e40e-4855-9ef7-be526c60cae3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_24625f0d-c362-4027-a97c-ca0232e305ff" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_958b2362-e40e-4855-9ef7-be526c60cae3" xlink:to="loc_srt_ProductOrServiceAxis_24625f0d-c362-4027-a97c-ca0232e305ff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_5153615a-4a9f-41c1-bbc4-a807ef313662" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_24625f0d-c362-4027-a97c-ca0232e305ff" xlink:to="loc_srt_ProductsAndServicesDomain_5153615a-4a9f-41c1-bbc4-a807ef313662" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_74071d95-52a0-41bf-99f7-87441188bed3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_5153615a-4a9f-41c1-bbc4-a807ef313662" xlink:to="loc_us-gaap_ProductMember_74071d95-52a0-41bf-99f7-87441188bed3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_b80c8996-6d99-4573-adcf-10c29287b3cb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_958b2362-e40e-4855-9ef7-be526c60cae3" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_b80c8996-6d99-4573-adcf-10c29287b3cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_68068efd-212b-41c2-9424-83104c2769ea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_b80c8996-6d99-4573-adcf-10c29287b3cb" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_68068efd-212b-41c2-9424-83104c2769ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_16a4d193-d9fa-4d84-aaa5-f066bc516769" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_68068efd-212b-41c2-9424-83104c2769ea" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_16a4d193-d9fa-4d84-aaa5-f066bc516769" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_d3c74e51-ec36-4ef2-8a50-139e4f75f5ae" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_958b2362-e40e-4855-9ef7-be526c60cae3" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_d3c74e51-ec36-4ef2-8a50-139e4f75f5ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_0d98b614-433f-4112-9ed7-892845c77871" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_d3c74e51-ec36-4ef2-8a50-139e4f75f5ae" xlink:to="loc_us-gaap_EquityComponentDomain_0d98b614-433f-4112-9ed7-892845c77871" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_6c4d2f10-5cb5-4127-a763-99cb99b4f3f7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_0d98b614-433f-4112-9ed7-892845c77871" xlink:to="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_6c4d2f10-5cb5-4127-a763-99cb99b4f3f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_f289392f-e5fc-4a7a-99a3-6c7efb123534" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_958b2362-e40e-4855-9ef7-be526c60cae3" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_f289392f-e5fc-4a7a-99a3-6c7efb123534" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_0ef0a904-189d-4e3b-a575-3921d8e5baa3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_f289392f-e5fc-4a7a-99a3-6c7efb123534" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_0ef0a904-189d-4e3b-a575-3921d8e5baa3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember_39c6db4f-5ac8-4cac-a17f-26a76ef5cb12" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_0ef0a904-189d-4e3b-a575-3921d8e5baa3" xlink:to="loc_us-gaap_ForeignExchangeContractMember_39c6db4f-5ac8-4cac-a17f-26a76ef5cb12" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CrossCurrencySwapContractsMember_dbb9a9f4-3578-4601-9183-1daf754e4641" xlink:href="amgn-20210930.xsd#amgn_CrossCurrencySwapContractsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_0ef0a904-189d-4e3b-a575-3921d8e5baa3" xlink:to="loc_amgn_CrossCurrencySwapContractsMember_dbb9a9f4-3578-4601-9183-1daf754e4641" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember_e346355d-cffe-422f-b651-c5f0baf1f9f3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateSwapMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_0ef0a904-189d-4e3b-a575-3921d8e5baa3" xlink:to="loc_us-gaap_InterestRateSwapMember_e346355d-cffe-422f-b651-c5f0baf1f9f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_233c815e-fe54-4252-9237-9647f6366bcf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_958b2362-e40e-4855-9ef7-be526c60cae3" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_233c815e-fe54-4252-9237-9647f6366bcf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_91c1f03e-d6dd-45ab-8979-9de2351b8df4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_233c815e-fe54-4252-9237-9647f6366bcf" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_91c1f03e-d6dd-45ab-8979-9de2351b8df4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_2605c90d-4d1e-49b3-ae29-c6ba047ba05f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NonoperatingIncomeExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_233c815e-fe54-4252-9237-9647f6366bcf" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_2605c90d-4d1e-49b3-ae29-c6ba047ba05f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebt_d6ac1413-0ccf-4fa8-aedc-ac11c9882d37" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestExpenseDebt"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_233c815e-fe54-4252-9237-9647f6366bcf" xlink:to="loc_us-gaap_InterestExpenseDebt_d6ac1413-0ccf-4fa8-aedc-ac11c9882d37" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1_0197c83e-8233-4113-bfe9-c6415d23f506" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_233c815e-fe54-4252-9237-9647f6366bcf" xlink:to="loc_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1_0197c83e-8233-4113-bfe9-c6415d23f506" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1_5d96087f-c571-4ed0-901b-018f3d8dec7c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_233c815e-fe54-4252-9237-9647f6366bcf" xlink:to="loc_us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1_5d96087f-c571-4ed0-901b-018f3d8dec7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#DerivativeinstrumentsFairValueofDerivativesDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_56cdd5c2-8868-48ff-b4f4-72961bce4829" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_bdfec912-97ea-4581-badf-3c2c9d0cda0a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_56cdd5c2-8868-48ff-b4f4-72961bce4829" xlink:to="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_bdfec912-97ea-4581-badf-3c2c9d0cda0a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationAxis_6dfb66ac-fa49-487a-930b-f57ec28abfa5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingDesignationAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_bdfec912-97ea-4581-badf-3c2c9d0cda0a" xlink:to="loc_us-gaap_HedgingDesignationAxis_6dfb66ac-fa49-487a-930b-f57ec28abfa5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_44748cbe-98f7-4654-85d7-6e444a8b1055" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HedgingDesignationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingDesignationAxis_6dfb66ac-fa49-487a-930b-f57ec28abfa5" xlink:to="loc_us-gaap_HedgingDesignationDomain_44748cbe-98f7-4654-85d7-6e444a8b1055" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_976c58a8-4065-4725-9bda-69ef0d14e6a0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingDesignationDomain_44748cbe-98f7-4654-85d7-6e444a8b1055" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_976c58a8-4065-4725-9bda-69ef0d14e6a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NondesignatedMember_fef4dde4-1f20-47fb-9d87-47db9fe1f594" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NondesignatedMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingDesignationDomain_44748cbe-98f7-4654-85d7-6e444a8b1055" xlink:to="loc_us-gaap_NondesignatedMember_fef4dde4-1f20-47fb-9d87-47db9fe1f594" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_2d50f2ec-0756-43c6-87d8-ea01689efb83" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_bdfec912-97ea-4581-badf-3c2c9d0cda0a" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_2d50f2ec-0756-43c6-87d8-ea01689efb83" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_f5b52be5-4b40-4955-bfa6-182585a59336" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_2d50f2ec-0756-43c6-87d8-ea01689efb83" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_f5b52be5-4b40-4955-bfa6-182585a59336" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember_283a244a-93b4-447d-954b-924884ee6b8b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_f5b52be5-4b40-4955-bfa6-182585a59336" xlink:to="loc_us-gaap_ForeignExchangeContractMember_283a244a-93b4-447d-954b-924884ee6b8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_CrossCurrencySwapContractsMember_cba910d9-b9a6-41c3-82da-989c9890403e" xlink:href="amgn-20210930.xsd#amgn_CrossCurrencySwapContractsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_f5b52be5-4b40-4955-bfa6-182585a59336" xlink:to="loc_amgn_CrossCurrencySwapContractsMember_cba910d9-b9a6-41c3-82da-989c9890403e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember_63d4b70a-406c-476d-b61a-ca4943446563" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateSwapMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_f5b52be5-4b40-4955-bfa6-182585a59336" xlink:to="loc_us-gaap_InterestRateSwapMember_63d4b70a-406c-476d-b61a-ca4943446563" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_73d994a1-7a4a-4951-bd59-c9ade06b2e4e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BalanceSheetLocationAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_bdfec912-97ea-4581-badf-3c2c9d0cda0a" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_73d994a1-7a4a-4951-bd59-c9ade06b2e4e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_c3f21ea3-c4b5-4b4f-9f6f-01154d571224" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BalanceSheetLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_73d994a1-7a4a-4951-bd59-c9ade06b2e4e" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_c3f21ea3-c4b5-4b4f-9f6f-01154d571224" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtherCurrentNoncurrentAssetsMember_2fcd3d93-23df-4b74-a86c-1dfb6221e3cf" xlink:href="amgn-20210930.xsd#amgn_OtherCurrentNoncurrentAssetsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_c3f21ea3-c4b5-4b4f-9f6f-01154d571224" xlink:to="loc_amgn_OtherCurrentNoncurrentAssetsMember_2fcd3d93-23df-4b74-a86c-1dfb6221e3cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember_f79e79be-7058-4fa7-93f3-1a0fac7486d0" xlink:href="amgn-20210930.xsd#amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_c3f21ea3-c4b5-4b4f-9f6f-01154d571224" xlink:to="loc_amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember_f79e79be-7058-4fa7-93f3-1a0fac7486d0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCurrentAssetsMember_5345e317-75b5-4087-9e4f-ce26f98c4817" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherCurrentAssetsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_c3f21ea3-c4b5-4b4f-9f6f-01154d571224" xlink:to="loc_us-gaap_OtherCurrentAssetsMember_5345e317-75b5-4087-9e4f-ce26f98c4817" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesMember_81b3234b-91b1-4de0-b5ba-ca925c170127" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccruedLiabilitiesMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_c3f21ea3-c4b5-4b4f-9f6f-01154d571224" xlink:to="loc_us-gaap_AccruedLiabilitiesMember_81b3234b-91b1-4de0-b5ba-ca925c170127" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativesFairValueLineItems_a7723455-256e-4b65-bd6c-79bd919248f2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativesFairValueLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_bdfec912-97ea-4581-badf-3c2c9d0cda0a" xlink:to="loc_us-gaap_DerivativesFairValueLineItems_a7723455-256e-4b65-bd6c-79bd919248f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract_88b244b5-31cd-4282-8cd6-6c5cc6e67049" xlink:href="amgn-20210930.xsd#amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_a7723455-256e-4b65-bd6c-79bd919248f2" xlink:to="loc_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract_88b244b5-31cd-4282-8cd6-6c5cc6e67049" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssetFairValueNetAbstract_4f07d9b8-da31-4479-b4be-5489c152248b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeAssetFairValueNetAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract_88b244b5-31cd-4282-8cd6-6c5cc6e67049" xlink:to="loc_us-gaap_DerivativeAssetFairValueNetAbstract_4f07d9b8-da31-4479-b4be-5489c152248b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_4ae7c70e-3daf-485a-980a-2c36ddda69f5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeAsset"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeAssetFairValueNetAbstract_4f07d9b8-da31-4479-b4be-5489c152248b" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_4ae7c70e-3daf-485a-980a-2c36ddda69f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilityFairValueNetAbstract_af807093-c46a-4fc6-95a6-f4f1663c790e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeLiabilityFairValueNetAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract_88b244b5-31cd-4282-8cd6-6c5cc6e67049" xlink:to="loc_us-gaap_DerivativeLiabilityFairValueNetAbstract_af807093-c46a-4fc6-95a6-f4f1663c790e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_1f8d3baf-72b0-4e82-9455-0717f1a2816f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeLiability"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLiabilityFairValueNetAbstract_af807093-c46a-4fc6-95a6-f4f1663c790e" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_1f8d3baf-72b0-4e82-9455-0717f1a2816f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/Contingenciesandcommitments" xlink:type="simple" xlink:href="amgn-20210930.xsd#Contingenciesandcommitments"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/Contingenciesandcommitments" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_f654dd46-73ed-4893-8eff-15f8ebc134f0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_84430cc5-b7b6-4abc-ad27-ec12a5bfdb24" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_f654dd46-73ed-4893-8eff-15f8ebc134f0" xlink:to="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_84430cc5-b7b6-4abc-ad27-ec12a5bfdb24" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/ContingenciesandcommitmentsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#ContingenciesandcommitmentsDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/ContingenciesandcommitmentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_e315ef9d-605d-4dca-a060-ad0faf24d219" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesTable_ee42aa44-9c60-40cc-afa7-6e02658afafb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingenciesTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_e315ef9d-605d-4dca-a060-ad0faf24d219" xlink:to="loc_us-gaap_LossContingenciesTable_ee42aa44-9c60-40cc-afa7-6e02658afafb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_d371d030-e321-4c53-8e79-32519dffd45e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_ee42aa44-9c60-40cc-afa7-6e02658afafb" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_d371d030-e321-4c53-8e79-32519dffd45e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_6e130849-f5ea-431b-bc8e-15356ccaf066" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_d371d030-e321-4c53-8e79-32519dffd45e" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_6e130849-f5ea-431b-bc8e-15356ccaf066" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_95ab7892-e80c-42fe-bfb8-542c38078632" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_6e130849-f5ea-431b-bc8e-15356ccaf066" xlink:to="loc_us-gaap_SubsequentEventMember_95ab7892-e80c-42fe-bfb8-542c38078632" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_8db50c94-e050-485e-bb4a-c07b58c439f4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingenciesByNatureOfContingencyAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_ee42aa44-9c60-40cc-afa7-6e02658afafb" xlink:to="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_8db50c94-e050-485e-bb4a-c07b58c439f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNatureDomain_912b80c5-f549-4128-9a34-5342beb50974" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyNatureDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_8db50c94-e050-485e-bb4a-c07b58c439f4" xlink:to="loc_us-gaap_LossContingencyNatureDomain_912b80c5-f549-4128-9a34-5342beb50974" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_PatentTrialAndAppealBoardPatentChallengesMember_0ec2c49c-6196-4b03-abcb-6f32c8c272db" xlink:href="amgn-20210930.xsd#amgn_PatentTrialAndAppealBoardPatentChallengesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyNatureDomain_912b80c5-f549-4128-9a34-5342beb50974" xlink:to="loc_amgn_PatentTrialAndAppealBoardPatentChallengesMember_0ec2c49c-6196-4b03-abcb-6f32c8c272db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseAxis_1bfe297b-f9c7-461b-ba70-721ec4d3cddc" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_LitigationCaseAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_ee42aa44-9c60-40cc-afa7-6e02658afafb" xlink:to="loc_srt_LitigationCaseAxis_1bfe297b-f9c7-461b-ba70-721ec4d3cddc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_LitigationCaseTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseAxis_1bfe297b-f9c7-461b-ba70-721ec4d3cddc" xlink:to="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_HospiraMember_4d48f517-f85e-4d17-9504-b98a77d9abb0" xlink:href="amgn-20210930.xsd#amgn_HospiraMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_HospiraMember_4d48f517-f85e-4d17-9504-b98a77d9abb0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_KANJINTIPatentLitigationMember_2d64f659-d1cd-4367-81c5-c30d76363002" xlink:href="amgn-20210930.xsd#amgn_KANJINTIPatentLitigationMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_KANJINTIPatentLitigationMember_2d64f659-d1cd-4367-81c5-c30d76363002" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_HumiraBiosimilarAntitrustClassActionsMember_78879f3e-a4d2-46cc-a3fb-537aded09293" xlink:href="amgn-20210930.xsd#amgn_HumiraBiosimilarAntitrustClassActionsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_HumiraBiosimilarAntitrustClassActionsMember_78879f3e-a4d2-46cc-a3fb-537aded09293" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_SensiparAntitrustClassActionsMember_59969e00-7806-42c7-ba9f-2ad0e083c95b" xlink:href="amgn-20210930.xsd#amgn_SensiparAntitrustClassActionsMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_SensiparAntitrustClassActionsMember_59969e00-7806-42c7-ba9f-2ad0e083c95b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_KyprolisMember_805ef105-9264-444a-9490-4d2e84e3149d" xlink:href="amgn-20210930.xsd#amgn_KyprolisMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_KyprolisMember_805ef105-9264-444a-9490-4d2e84e3149d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_KyprolisANDAPatentLitigationMember_b7a2ff18-a9d9-42fe-834e-af883902a7a3" xlink:href="amgn-20210930.xsd#amgn_KyprolisANDAPatentLitigationMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_KyprolisANDAPatentLitigationMember_b7a2ff18-a9d9-42fe-834e-af883902a7a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_NovartisPharmaAGMember_9116cfb4-2524-4261-a5db-ad368ce8eb6b" xlink:href="amgn-20210930.xsd#amgn_NovartisPharmaAGMember"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_NovartisPharmaAGMember_9116cfb4-2524-4261-a5db-ad368ce8eb6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_OtezlaANDAPatentLitigationMember_2893bb87-7a74-4ac5-8ce7-faa9a004f2e8" xlink:href="amgn-20210930.xsd#amgn_OtezlaANDAPatentLitigationMember"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_2baab3bd-281e-44ed-afe1-fa992745f014" xlink:to="loc_amgn_OtezlaANDAPatentLitigationMember_2893bb87-7a74-4ac5-8ce7-faa9a004f2e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingenciesLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_ee42aa44-9c60-40cc-afa7-6e02658afafb" xlink:to="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LitigationSettlementDamagesSoughtValue_eb1d60ed-2b69-490e-922a-135cb61ed010" xlink:href="amgn-20210930.xsd#amgn_LitigationSettlementDamagesSoughtValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_amgn_LitigationSettlementDamagesSoughtValue_eb1d60ed-2b69-490e-922a-135cb61ed010" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_be3aec0f-401d-4ded-bbd4-c0ea71bc9dc5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LitigationSettlementAmountAwardedFromOtherParty"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_be3aec0f-401d-4ded-bbd4-c0ea71bc9dc5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_e9c7af8c-5152-4b12-a75d-8765752f279d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyPatentsAllegedlyInfringedNumber"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_e9c7af8c-5152-4b12-a75d-8765752f279d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LossContingencyNumberOfLawsuits_8806d0cc-1c98-4115-85eb-7f16f197b724" xlink:href="amgn-20210930.xsd#amgn_LossContingencyNumberOfLawsuits"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_amgn_LossContingencyNumberOfLawsuits_8806d0cc-1c98-4115-85eb-7f16f197b724" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNumberOfPlaintiffs_1b1e7e90-06f8-4ff0-951d-756686808450" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyNumberOfPlaintiffs"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_LossContingencyNumberOfPlaintiffs_1b1e7e90-06f8-4ff0-951d-756686808450" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LossContingencyPatentsExpiredNumber_1302fcaf-dbdc-4ed2-9275-77d77d9d6586" xlink:href="amgn-20210930.xsd#amgn_LossContingencyPatentsExpiredNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_amgn_LossContingencyPatentsExpiredNumber_1302fcaf-dbdc-4ed2-9275-77d77d9d6586" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_LossContingencyAppealPeriod_38840a1f-2a56-4ab9-b07b-5784b6ba6a4c" xlink:href="amgn-20210930.xsd#amgn_LossContingencyAppealPeriod"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_amgn_LossContingencyAppealPeriod_38840a1f-2a56-4ab9-b07b-5784b6ba6a4c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_NumberOfAssertedPatents_270f5332-07da-479e-8e9f-ea1bb92218a8" xlink:href="amgn-20210930.xsd#amgn_NumberOfAssertedPatents"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_amgn_NumberOfAssertedPatents_270f5332-07da-479e-8e9f-ea1bb92218a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LitigationSettlementExpense_6c909a14-d844-4ac1-849a-8a37f0b50d90" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LitigationSettlementExpense"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_LitigationSettlementExpense_6c909a14-d844-4ac1-849a-8a37f0b50d90" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyClaimsSettledNumber_d4ac59f4-c89c-49d7-8b93-a17fb78341f2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyClaimsSettledNumber"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_LossContingencyClaimsSettledNumber_d4ac59f4-c89c-49d7-8b93-a17fb78341f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainContingencyPatentsFoundInfringedUponNumber_a1469445-9c25-414c-8f63-a3d3e88a7f50" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GainContingencyPatentsFoundInfringedUponNumber"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_GainContingencyPatentsFoundInfringedUponNumber_a1469445-9c25-414c-8f63-a3d3e88a7f50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyPendingClaimsNumber_4686f662-772a-4e27-857d-4f152f4ef2c8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyPendingClaimsNumber"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_ef067067-5038-41b0-b0d9-77323844e584" xlink:to="loc_us-gaap_LossContingencyPendingClaimsNumber_4686f662-772a-4e27-857d-4f152f4ef2c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/Subsequentevents" xlink:type="simple" xlink:href="amgn-20210930.xsd#Subsequentevents"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/Subsequentevents" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_cdd91c00-29c1-4729-8364-ca0cd24aea48" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsTextBlock_6f807f6b-d413-48dc-a74d-6f3c3d423665" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_cdd91c00-29c1-4729-8364-ca0cd24aea48" xlink:to="loc_us-gaap_SubsequentEventsTextBlock_6f807f6b-d413-48dc-a74d-6f3c3d423665" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.amgen.com/role/SubsequenteventsDetails" xlink:type="simple" xlink:href="amgn-20210930.xsd#SubsequenteventsDetails"/>
  <link:presentationLink xlink:role="http://www.amgen.com/role/SubsequenteventsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_2f7fa6b6-0a44-4947-a9b9-dc8c6813dc06" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTable_08933f88-cec4-48ff-a3d1-bcbb7cfe09c0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_2f7fa6b6-0a44-4947-a9b9-dc8c6813dc06" xlink:to="loc_us-gaap_SubsequentEventTable_08933f88-cec4-48ff-a3d1-bcbb7cfe09c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementScenarioAxis_c92011cd-558e-4244-b000-27f5465a8c0b" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_StatementScenarioAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_08933f88-cec4-48ff-a3d1-bcbb7cfe09c0" xlink:to="loc_srt_StatementScenarioAxis_c92011cd-558e-4244-b000-27f5465a8c0b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain_2714fb9a-1360-43dd-9ef1-03343c67c686" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ScenarioUnspecifiedDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_StatementScenarioAxis_c92011cd-558e-4244-b000-27f5465a8c0b" xlink:to="loc_srt_ScenarioUnspecifiedDomain_2714fb9a-1360-43dd-9ef1-03343c67c686" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioForecastMember_37c7ed8f-be12-42ef-a852-4d7e34d224f8" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ScenarioForecastMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ScenarioUnspecifiedDomain_2714fb9a-1360-43dd-9ef1-03343c67c686" xlink:to="loc_srt_ScenarioForecastMember_37c7ed8f-be12-42ef-a852-4d7e34d224f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_baccf25a-f8e0-4276-8636-81f1fbabb1ab" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_08933f88-cec4-48ff-a3d1-bcbb7cfe09c0" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_baccf25a-f8e0-4276-8636-81f1fbabb1ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_9d324147-144f-4d15-b7e3-f11219a14c38" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_baccf25a-f8e0-4276-8636-81f1fbabb1ab" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_9d324147-144f-4d15-b7e3-f11219a14c38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_TeneobioIncMember_ce22d6ff-6b93-4829-a631-7255d16b183a" xlink:href="amgn-20210930.xsd#amgn_TeneobioIncMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_9d324147-144f-4d15-b7e3-f11219a14c38" xlink:to="loc_amgn_TeneobioIncMember_ce22d6ff-6b93-4829-a631-7255d16b183a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_b1a4ae76-de6d-4b45-947e-387259aa3f2a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_08933f88-cec4-48ff-a3d1-bcbb7cfe09c0" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_b1a4ae76-de6d-4b45-947e-387259aa3f2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_624b7d05-51ef-4399-8955-dd70b8916629" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_b1a4ae76-de6d-4b45-947e-387259aa3f2a" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_624b7d05-51ef-4399-8955-dd70b8916629" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_fca423df-7fa1-4ea2-8c08-3c8e9ee582c4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_624b7d05-51ef-4399-8955-dd70b8916629" xlink:to="loc_us-gaap_SubsequentEventMember_fca423df-7fa1-4ea2-8c08-3c8e9ee582c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventLineItems_87282682-c37c-44b3-b71d-137ddc48eb15" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_08933f88-cec4-48ff-a3d1-bcbb7cfe09c0" xlink:to="loc_us-gaap_SubsequentEventLineItems_87282682-c37c-44b3-b71d-137ddc48eb15" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_UpFrontPayment_077b74a9-97db-48e5-a904-6a37364ede6e" xlink:href="amgn-20210930.xsd#amgn_UpFrontPayment"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_87282682-c37c-44b3-b71d-137ddc48eb15" xlink:to="loc_amgn_UpFrontPayment_077b74a9-97db-48e5-a904-6a37364ede6e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions_a8c90466-1a18-45d0-a85a-760d5f88f887" xlink:href="amgn-20210930.xsd#amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_87282682-c37c-44b3-b71d-137ddc48eb15" xlink:to="loc_amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions_a8c90466-1a18-45d0-a85a-760d5f88f887" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesGross_87661944-6032-4367-a335-9cc94e5e345d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesGross"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_87282682-c37c-44b3-b71d-137ddc48eb15" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesGross_87661944-6032-4367-a335-9cc94e5e345d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_bd7e3a65-12e4-4e20-88bc-f18d442e9eb8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_87282682-c37c-44b3-b71d-137ddc48eb15" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_bd7e3a65-12e4-4e20-88bc-f18d442e9eb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>10
<FILENAME>amgn-20210930_htm.xml
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<XML>
<?xml version="1.0" encoding="utf-8"?>
<xbrl
  xml:lang="en-US"
  xmlns="http://www.xbrl.org/2003/instance"
  xmlns:amgn="http://www.amgen.com/20210930"
  xmlns:country="http://xbrl.sec.gov/country/2021"
  xmlns:currency="http://xbrl.sec.gov/currency/2021"
  xmlns:dei="http://xbrl.sec.gov/dei/2021"
  xmlns:exch="http://xbrl.sec.gov/exch/2021"
  xmlns:iso4217="http://www.xbrl.org/2003/iso4217"
  xmlns:link="http://www.xbrl.org/2003/linkbase"
  xmlns:srt="http://fasb.org/srt/2021-01-31"
  xmlns:us-gaap="http://fasb.org/us-gaap/2021-01-31"
  xmlns:xbrldi="http://xbrl.org/2006/xbrldi"
  xmlns:xlink="http://www.w3.org/1999/xlink"
  xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <link:schemaRef xlink:href="amgn-20210930.xsd" xlink:type="simple"/>
    <context id="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i0be1039089ac48b9949c7220072783f8_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:EntityListingsExchangeAxis">exch:XNGS</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i7aae778309b84991a0bcd8e16938fcf6_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">amgn:A1.250SeniorNotesDue2022Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:EntityListingsExchangeAxis">exch:XNGS</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="if48b7c2672244974ae505e9c06ea1da9_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis">amgn:A2.00SeniorNotesDue2026Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="dei:EntityListingsExchangeAxis">exch:XNGS</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="id260522a4d634e208edb416383a7443e_I20211028">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <instant>2021-10-28</instant>
        </period>
    </context>
    <context id="i237db287808149dc88791dd0402e8c8d_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="icc3aae43096e4ee2941dfecfdc9776ad_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i3eb445431b634cc6b3e61727cef7b877_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i556e038dae96477cbe84bc1653ed5883_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i488eb65c564543e1895d64ea848f40c4_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductAndServiceOtherMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="id0ffdac343f944aaa636865f0a68567e_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductAndServiceOtherMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="iddf8eed0ade74615b203cae47895e098_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductAndServiceOtherMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ia3ba4d704ab343159b80e5ecde0bf68b_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductAndServiceOtherMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i5c9f553a648c448983067995570fff40_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i74edd277075b4be0b03a288e4d476372_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="if5d69d61a77e45e8a5690b1247306be3_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i3fa2d8396a304f96bf7624f5d6125c76_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i091ea451ee5b401e9a692e47a31d079b_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i85eb1be2504f43d5b6b300dc199131eb_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i8fd3f59d080644dfb1308254046fba14_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="iaea9ac2193424d918f03fbf56ef30362_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ia7cc3209b62b4e859989adf72041bfb0_D20210101-20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-03-31</endDate>
        </period>
    </context>
    <context id="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-03-31</endDate>
        </period>
    </context>
    <context id="i8ff5ee6ed2904950abde3e69e298a888_D20210101-20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-03-31</endDate>
        </period>
    </context>
    <context id="i7969d970f6a54e60804bc95280496c8b_D20210101-20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-03-31</endDate>
        </period>
    </context>
    <context id="i2dcd4eff17124be29dcc8becb0415e77_D20210101-20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-03-31</endDate>
        </period>
    </context>
    <context id="ib60c8e3ee5494c37bc18cec8bd0c619c_I20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-03-31</instant>
        </period>
    </context>
    <context id="i79a13e6805f34de1abc4d45f73bf3010_I20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-03-31</instant>
        </period>
    </context>
    <context id="ifd05c4dcf2974888bb7ea94987a2302e_I20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-03-31</instant>
        </period>
    </context>
    <context id="i02d7483a082146bca57a490cca649110_I20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-03-31</instant>
        </period>
    </context>
    <context id="i65ba920729294b6ca0d58b7c3d55da64_I20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <instant>2021-03-31</instant>
        </period>
    </context>
    <context id="i7a34b44a0b684692a8ce01f962435f05_D20210401-20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-04-01</startDate>
            <endDate>2021-06-30</endDate>
        </period>
    </context>
    <context id="if25ef868ecd240a3b1467e666429713f_D20210401-20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <startDate>2021-04-01</startDate>
            <endDate>2021-06-30</endDate>
        </period>
    </context>
    <context id="ic34d84ceeae14872821180cf4d7c1fc9_D20210401-20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-04-01</startDate>
            <endDate>2021-06-30</endDate>
        </period>
    </context>
    <context id="ibcaee6c81e1645c98fc9f7046d1c84b0_D20210401-20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-04-01</startDate>
            <endDate>2021-06-30</endDate>
        </period>
    </context>
    <context id="i2ed57ff3dbc9401b9e0afd3df0e57952_D20210401-20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-04-01</startDate>
            <endDate>2021-06-30</endDate>
        </period>
    </context>
    <context id="ib91fd46e082e435c8604678dba5c6807_I20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-06-30</instant>
        </period>
    </context>
    <context id="i3ee32787b0ee44f7835a1897d7ccc133_I20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-06-30</instant>
        </period>
    </context>
    <context id="ib9c55bd482c8427c869df819585fe64b_I20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-06-30</instant>
        </period>
    </context>
    <context id="i9d079f6d807e45a8b0ea7b4bf5ca1b1c_I20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-06-30</instant>
        </period>
    </context>
    <context id="ibb4ad07750104a41ad551ce7e97f7afe_I20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <instant>2021-06-30</instant>
        </period>
    </context>
    <context id="i6271ffbf65cf467783eea9a8f4a54fb0_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i984e708e2ca94952a077181e38e25d78_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i967296e305e04ee0ba9de8194bd5c859_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ia9f1d012da3a43b89a1c71ec6c7599ff_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i326b605172394be1a3158d27be23c5d3_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="id005bde0830f48398b26dea00beb0a27_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i3deeda31d541496fbfdcf359358e2e31_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ic860f31327384ad08f5dbf6d59cdb763_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i9383ea8be6554a1fab020c889f98f560_I20191231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2019-12-31</instant>
        </period>
    </context>
    <context id="i9fa8d9073cbb4a5e8bd57d0450a06268_I20191231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2019-12-31</instant>
        </period>
    </context>
    <context id="i27c34688721e4c3eab67f6dfab55e1ea_I20191231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2019-12-31</instant>
        </period>
    </context>
    <context id="i3b1542b7bb8c42d092dd7b4a59e1c916_I20191231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2019-12-31</instant>
        </period>
    </context>
    <context id="id63942c02328404c8dac62b9840ef120_I20191231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <instant>2019-12-31</instant>
        </period>
    </context>
    <context id="iac88abda0f2a4f44ab3e6e7248813631_I20191231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CumulativeEffectPeriodOfAdoptionAxis">srt:CumulativeEffectPeriodOfAdoptionAdjustmentMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2019-12-31</instant>
        </period>
    </context>
    <context id="i093220b291f2482d91c2fbc2c9ffff00_I20191231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CumulativeEffectPeriodOfAdoptionAxis">srt:CumulativeEffectPeriodOfAdoptionAdjustmentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2019-12-31</instant>
        </period>
    </context>
    <context id="ic041513a75144cdd9d651b4d92760425_D20200101-20200331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-03-31</endDate>
        </period>
    </context>
    <context id="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-03-31</endDate>
        </period>
    </context>
    <context id="i1203a51d54b041baa767dda74da28ae7_D20200101-20200331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-03-31</endDate>
        </period>
    </context>
    <context id="i2ce25f9016044114882e77dd2ae1c3db_D20200101-20200331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-03-31</endDate>
        </period>
    </context>
    <context id="i8d2a343e4cc5455eb9ba7ef31b5fc432_D20200101-20200331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-03-31</endDate>
        </period>
    </context>
    <context id="ibc414a46e88b4e40a79c00cb9bfd0717_I20200331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-03-31</instant>
        </period>
    </context>
    <context id="i8ff21ac5e59f4e1c9aaf71c8a6427a9b_I20200331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-03-31</instant>
        </period>
    </context>
    <context id="ieb7177b91ced43c4bb32d3c71fc60664_I20200331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-03-31</instant>
        </period>
    </context>
    <context id="i9ab337ca3f8b490685a1514d21ef0795_I20200331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-03-31</instant>
        </period>
    </context>
    <context id="i97aafa8c1ca149ab98952ad235869d3d_I20200331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <instant>2020-03-31</instant>
        </period>
    </context>
    <context id="iad1c7381eead460f9f20a42237bbc0ab_D20200401-20200630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-04-01</startDate>
            <endDate>2020-06-30</endDate>
        </period>
    </context>
    <context id="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <startDate>2020-04-01</startDate>
            <endDate>2020-06-30</endDate>
        </period>
    </context>
    <context id="ia9f6aa7d77f443dfb9ccbbf4060d7af0_D20200401-20200630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-04-01</startDate>
            <endDate>2020-06-30</endDate>
        </period>
    </context>
    <context id="if8027892520a4ca5bd94f4c5cfcec8a0_D20200401-20200630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-04-01</startDate>
            <endDate>2020-06-30</endDate>
        </period>
    </context>
    <context id="i7896d230ca994182af0336d7fc0f319c_D20200401-20200630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-04-01</startDate>
            <endDate>2020-06-30</endDate>
        </period>
    </context>
    <context id="ia393209bc348462397965e66e877a084_I20200630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-06-30</instant>
        </period>
    </context>
    <context id="i8a3527abf717402c896edf9e49b60c2b_I20200630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-06-30</instant>
        </period>
    </context>
    <context id="i9c61b9be9ad3458088feb12ba9d330d6_I20200630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-06-30</instant>
        </period>
    </context>
    <context id="ib5bc8ed5ffb54e45bdec39111af0f8d5_I20200630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-06-30</instant>
        </period>
    </context>
    <context id="i0d016fa4aa4b4b0b8d61f8f03d2b1ad9_I20200630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <instant>2020-06-30</instant>
        </period>
    </context>
    <context id="i2fdcbf2c5023490a8467f390d0945384_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ia0027870c8424e858af8516bb7a32d5b_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ia750b0fd2e8d494f82d6c68132072625_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="if9b3a6e30225464792dc4e6abbd3a015_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="id0c6f5eb460b4312bb606fc4ad30a816_I20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-09-30</instant>
        </period>
    </context>
    <context id="i7ca21439af704771b81a4e07e28ca15c_I20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:CommonStockIncludingAdditionalPaidInCapitalMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-09-30</instant>
        </period>
    </context>
    <context id="i18ba9dc7e2ca40f5b5ccd5e684f54c7a_I20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:RetainedEarningsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-09-30</instant>
        </period>
    </context>
    <context id="i5368a3d307444f2c801d6b1d0963ec11_I20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-09-30</instant>
        </period>
    </context>
    <context id="i1a997bb47af74377a26fb3c2164ec5a6_I20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <instant>2020-09-30</instant>
        </period>
    </context>
    <context id="i65976c78d95c49118311d26eb3256876_D20210416-20210416">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:FivePrimeTherapeuticsIncMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-04-16</startDate>
            <endDate>2021-04-16</endDate>
        </period>
    </context>
    <context id="ifd83e7d77b084c5d854ddc58d39a3bcf_I20210416">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:FivePrimeTherapeuticsIncMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-04-16</instant>
        </period>
    </context>
    <context id="ic6cdb58f08f6497e9571e255839b182e_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="idb19909eae6245c0b192e54299cbf115_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="iff8d101adf4b402f8cf46cf5dcd93486_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i8c7cf69cd4834e9c85f4459b2de8d602_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i881925882b374e84accf889451f21493_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i3580e2b0cb29470bad2033dc2b011286_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i928ab90d0db745ea81bb2a93d965f16e_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ia5bb4cc11d6c483d8309a8c954255a3c_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i5ad790cbfd31467bb8daa208b16d7e6e_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="iee4b7620a6e94b15a0ee2efa21046c26_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ic41a377f5b39468994f26d4f4fb0aa51_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i9e2067897ce84b959d0906d105ab21e8_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ica2c1ae056384bd5808311f2c76005bd_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i1e4fbb00243e4f62ba164169062363bd_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="id03562c57df94c4695307d990b6d880d_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ie59bcfe33b8147c0b1c58739ec6f4501_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i7d0db737d136412cabc053873e3c0f55_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i997de67b4d8041fd92aa65650ae56646_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i6be8feef3fae4c3ab81bc1a648281c8c_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ib1e795008cb04855b4f4ada989eec622_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i7fb5d6e70e864ca9a24965da716a59f9_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i8f5c65603d3b495a97c04bb49c2930c7_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="if2f93bdf48274317b1da0bbaad739897_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i6d80e26ad167494498b23e0ca5271458_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i17187759eba94aadb3d31a3510ebf19e_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i641be115cab64df981d42cdd9261ce71_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i368f295d54bd4525bb8eb6714d3d0066_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="icf361ee93a5a459fb961382bfdaab897_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="iae3f58a4ca5c4ee6b7a5efa557d3239e_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i89c0f0d97cef4bd6b1184caf279f571a_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i739f696b931d4702b3df5ae6ca746716_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="if968e6327f794c59a9ba65fc3208a8f6_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ic9d9abb7215c47c2a1aca1be0668980f_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i5b3ef1a8e7f545cfa45814ef6cc1e9ef_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i65474b7854d64aadbcea001bcca67fcc_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="id84e814556764ab79f45c36978bd96e4_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i39b00b7d625e4f6487ec0db17bdc442d_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i817db5726ac748d4bd491dbef24298e8_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="if48659bf944e4492a4dafa719e7083d0_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i7b514b2a404649a58ac1b9f9087c9ed6_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i69c93666703d4eac86caffd587b7db7d_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i0dea61c77564492ab39c0a6ee2a71ffb_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i643c94b54a124674bdf0a819e67e429b_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i21f6d8435c474c6980866635aeee71e9_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i0c97db9ff3494e8c8961a94b3979974b_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i36d299d1d5a642cca156e5411c4b4fc8_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ifadfb5ce284249b49c5b541e46f8fd6d_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ibb9fffae57f44694bf945745287d733a_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i2f0871bad93240bd851a8f0aaa387350_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i10acdfdcf69c40c2a0bdc6d3e81fb337_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i23817bdf825e4ae1ac3362ea0639d136_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i0beb71107b234faea29110b3fa9d8a98_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ic81b8501b6db4aee88091da6a3afdf07_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="if807b6245b86445088eb952987a6b469_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ia3c6be49d4364b1f9f7490f5b324e697_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i2032ce010c324b94be367952c9e7ba79_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i8b0da7f54b9d44ec896bac0ef1d0eb58_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i05cbea6753bb40cc89759fbeb6e01550_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ia48b8184147044458082feb5ea147e49_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i99ffbf75ddf84e1e9245421a8c01d767_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="idab45a332369432d9ebd6f50b96a8f56_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ica6caa6433a24945a279239a702b2abf_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ic1bb05a1b59b4da5902e961b2a5533a0_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i7cbcc55bfaff415a96eaa73c996dbb6a_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:EnbrelMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="iaf3073b6b8e349c9b88d3cb4f719e628_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ib9e71fbc76704655955f107a3a191a9c_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ide3ecdc601c44f8d89456132330e9af2_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i17357cd18fe541d0a042e9ee59c93b38_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ib3777a2c9f034e97919676bb7754de25_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i6b5f2a9043d945b08ec0167f3cfed9f2_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:ProliaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i95957399b3a14e7383788a66404fcbbb_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i78293d5fa71b41ef9cc01a231545bab2_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i195420e0531242db9f936a0127259be3_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="if0fb79f0bfbc4e51b7cb42fd1d71c840_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i68bf0dc18c0d4ffa9e9a898ff74c54f1_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ibe1bd36ce26a43fe9cb844c7326c4e54_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtezlaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i7da33cf805a445869662f5abc2106d6d_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ia6106c345460401c9e03019b7c080699_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i443bd36291d548a0aa9856e73206eac6_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="id7ca09709e904974a92ad3adb8b9fd77_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i98005524cd124b8c966a68f6bdcfb8fc_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i5b4401a3903c4c908d2eb7fe95caad21_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:XgevaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i3cd61c0be22f4420b7238ce5a6df9130_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="iae6381714cfe468aa29ce147540ec7e9_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i96040b94405a4bd1a72890459e71ee00_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="iad909099174b42f681a09827cb78f0a7_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i9445f98f484747b89af2e9d73ea09d95_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ib01fa4a797464e63b788127b5705e442_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:NeulastaMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i4f38a5540cd04d718fff14e7bd440bf3_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ia48c696724e24052ae23b516c63d79e2_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ic91169bf44324e9c8beba26b3f9827e7_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i749f9c098fc64abb9167bd96645abed7_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="id2cb108abc1b4ddc9555fa47ab4e573b_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i576d061a6ae043e0829b0988a7faa3ec_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:AranespMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ic52c02bf054740ada11032b24246ae68_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ic6cc0b13a201477e8bdc3a92299b7b68_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="id29b4587abfe4026b9589b04316507cb_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i99a4a03013b04d41935e841bd095d3a7_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i6a2c38f1abb049d190286ec739f3d8ae_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ieb422a6656b54be5afd83d1c3557841c_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:RepathaevolocumabMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="iee523348acf64084b9744fc397411af6_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ie2fb5db5ef234ceba2e63133b46811d9_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ia1236d7f1db54d0cbbb4bb10634d9cbd_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i700316332e8941abafe598d080cee8ed_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i2237615b64f7401e880801b52e994daf_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i3367f489225f42e490b5ec1bd448da76_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:KyprolisMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ie4393fb731674dae95e49ebf43c2dc17_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i2d608ed82a0642d2bd3d2585175ab0df_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i7ec4a6f423c548c287970aa87131e9c9_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i277af735bdea4ca1ad4911bd0724214d_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i547f36d7acb3432789479ca670e2143f_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i6ddfacf19b5b4634890a1b86f11498d4_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">amgn:OtherProductsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="iec4ac6803eb24d47ae70292430854aee_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i11c711a9331e402aa04c6f1100a9a662_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="icc040f113aa74ff9aa98ca66ae336cbf_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">country:US</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i03039f45f78c4280b4623c349760790f_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="srt:StatementGeographicalAxis">us-gaap:NonUsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i91b6753ab42449599e1e80924db35109_I20210531">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <instant>2021-05-31</instant>
        </period>
    </context>
    <context id="icb5563aa4d0b4e68b3266d16db71f2a1_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">amgn:KyowaKirinCoLtdMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i1dfc25edd9d84950bcbf296614e005a4_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:TypeOfArrangementAxis">amgn:KyowaKirinCoLtdMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i0523566bb4bd4ac7a167861d41b07412_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i8db023e72bf0457098764c83dfe06255_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i3022e170e868460588b8873ad8b918de_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ic7d3b5bd8e574e95949520f4cff15af1_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i507488fbf87d4c6296eb13e3e0006fbf_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i8ba30f0c09fc4bfd9fe36a47079d2854_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i54f838959ac943e79d09dcf9e6faada4_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i84edbdc908bc4493a769cf963ac32f28_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i6a8d71c465184aa38c33193a90315560_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:AvailableForSalesInvestmentsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="if5d779b254da4c18b8454e5bf7051777_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:AvailableForSalesInvestmentsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ib2b89ed4eb094c5f966961837399b7ca_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ia0271b62203b4afbbefbea6461a32a14_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i88ba0aea99ef48b08518a135f9c253ef_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:BeiGeneMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ib7d74024b547459c9c043788d26b2171_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:BeiGeneMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i425bed6d2b57481aba5c27ce44f41234_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:BeiGeneMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i14a1d9538f0a492885a9966112c392aa_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:NeumoraTherapeuticsIncMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i3c3ace434f6b40b4a14815a09b06178b_D20210930-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:NeumoraTherapeuticsIncMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-09-30</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ic38268b0440c4532956b86d64e30b988_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueMeasuredAtNetAssetValuePerShareMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:InvestmentTypeAxis">srt:PartnershipInterestMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i84a786cd4d99438e85fec21c4c798f36_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueMeasuredAtNetAssetValuePerShareMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:InvestmentTypeAxis">srt:PartnershipInterestMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i01c954a7c8fa422990f7456e349536ec_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueMeasuredAtNetAssetValuePerShareMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:InvestmentTypeAxis">srt:PartnershipInterestMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i9a95e7ba909f487d97ae171134923478_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueMeasuredAtNetAssetValuePerShareMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:InvestmentTypeAxis">srt:PartnershipInterestMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i2fcb95887a864539b58641131094dfd5_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueMeasuredAtNetAssetValuePerShareMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:InvestmentTypeAxis">srt:PartnershipInterestMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i7d119868ff92459e8484a254322dda06_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueMeasuredAtNetAssetValuePerShareMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:InvestmentTypeAxis">srt:PartnershipInterestMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i9160bae8d5f74cf4a23fbe7ba32fa1b6_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:DevelopedTechnologyRightsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ibb2cb97dcaa2448f8abb52ea2809f752_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:DevelopedTechnologyRightsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="iccda3c90f3ea4d7ca11b1e7e5979139f_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:LicensingAgreementsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i7bfe3a17c67f48848b0a262301253745_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:LicensingAgreementsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ie5cd36de21a24c3a974d783bc31683e3_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:MarketingRelatedIntangibleAssetsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ifa42c9c20230405db95ebc7c2717a086_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:MarketingRelatedIntangibleAssetsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i823fc181443240599bbbbaad667a7fd2_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">amgn:AcquiredResearchAndDevelopmentTechnologyRightsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i3c93fbbb176e41ab97226ab5c020020d_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FiniteLivedIntangibleAssetsByMajorClassAxis">amgn:AcquiredResearchAndDevelopmentTechnologyRightsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i62a4ce9947344dd28aeec0db74164aef_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IndefiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:InProcessResearchAndDevelopmentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i858e9c4fb9dc48f1b8c2568fc92c7dfd_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:IndefiniteLivedIntangibleAssetsByMajorClassAxis">us-gaap:InProcessResearchAndDevelopmentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i28a3a2e4d2f24ec1ab05429cee726f75_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i1d8b35fb400b4d018ac1fc3ac92c4e11_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="iba85a821e6d84b96a52fc42ef1b75604_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ia88d5a3b1b5c414db7ff8890b7c96f91_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i1a04775f93b24e3c83787a805db33fd7_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSixFiveNotesDue2022Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i071cb4027c8549148b8bd96aea3e7c5c_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSixFiveNotesDue2022Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ib744f296eafb4f8d88d2a38efb8a48a3_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointSixTwoFivePercentNotesDue2022Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ie50a52f9a64743be865aca69358499b2_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointSixTwoFivePercentNotesDue2022Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="id0d88ff8ca444d28a9d31155d2af6123_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="iaccb7326e7d146e0aafad220d316b604_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="id7b48ebaee8d4fddada565c9d549a4af_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="id1e3e3f0ae1a4a3fb3b7e07bf050efd6_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i14cb17bbd31f41deb2c7c3feb4b40b34_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointSixTwoFivePercentNotesDue2024Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i3f99f7b28ace4d3b80f5f9385a149eaf_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointSixTwoFivePercentNotesDue2024Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i3e1c0c3571924fcf9795dd47036e02c4_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i1ad59cf770774b36883e5e3f187962e3_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ib8287a44e2c445c2acd186f4936f5772_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i6be009b691aa4576ac79c8915e21298d_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i35556fe1ea36409196d95de0bec85fae_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPercentEuroNotesDueTwoThousandTwentySixMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="iee3ca7ca07cc4b1b82dc3946ebca7fda_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPercentEuroNotesDueTwoThousandTwentySixMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i52dee93b650b4cd8868ed20f7cf964bc_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSixZeroNotesDueTwoZeroTwoSixMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i98166ba2f34643ffafa2e088bf573187_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSixZeroNotesDueTwoZeroTwoSixMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ib9a2ddc95a504747aa69a99a4d875fea_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointFiveZeroPercentPoundSterlingNotesDue2026Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ic87056a5fa024aba8b55cbd31c06353a_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointFiveZeroPercentPoundSterlingNotesDue2026Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i5285c4d278d54713b60c0cc0f87aa46a_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i6bb96c6e9f4048dfa94c91a4ab648b6a_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i705890d8cae541638f21f7669dbe4b04_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointTwoZeroNotesDue2027Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ieb62499093c345529236e71f444d0853_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointTwoZeroNotesDue2027Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ibda3099c78a845a98d23ce711d8447f6_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointSixFivePercent2028NotesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ibb2e9e5c4f2a4bbf841a6bc671651b19_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointSixFivePercent2028NotesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i407ab77f9d0440acae9fe2fc19c63542_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPercentPoundSterlingNotesDue2029Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i000f9a5c0b8f4cd99faa556d2ea850e6_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPercentPoundSterlingNotesDue2029Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ia3569d0c6bcd4203a1148cb8dda584fe_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointFourFivePercentNotesDue2030Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="id46fc442a7f34ba2afc285c190d4a3c5_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointFourFivePercentNotesDue2030Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i2c54babb8e9f4eb8b43722a88181da66_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointThreeZeroPercentNotesDue2031Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i2f896bd90bd24cfcbf6f31271e9148e9_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointThreeZeroPercentNotesDue2031Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i220407dac7c34df4809bfc677b8b3503_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointZeroPercent2032NotesMemberMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i10faa7c13c3447bbbc7cfae536e3c802_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:SixPointThreeSevenFivePercentNotesDue2037Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ia6787d1b183a4eaf8408dbce1815a07c_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:SixPointThreeSevenFivePercentNotesDue2037Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="iac7d798f49894466bc42c0153cdf0595_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:SixPointNineZeroPercentNotesDue2038Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ib5e6389f8cf6478dbebef3136cee8c23_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:SixPointNineZeroPercentNotesDue2038Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i512d102f92cd4cc2833291c7e8cd520d_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:SixPointFourZeroPercentNotesDue2039Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i6af736050aa24649ab1cfff13dee1b92_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:SixPointFourZeroPercentNotesDue2039Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i99981976037d4cef90e95f33441854b2_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointOneFivePercentNotesDue2040Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="id540a747481347329775d9396bb889d2_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointOneFivePercentNotesDue2040Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i00fb0934241248439eae35efb4b7888e_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointSevenFivePercentNotesDue2040Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ib61d19755e0742c09a249871a640ecd1_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointSevenFivePercentNotesDue2040Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="id14f137f4c5e454687d4fbce9656c938_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointEightZeroPercent2041NotesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="id4a29b7b702446d0b6a2302a87559c9a_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointNineFivePercentNotesDue2041Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i891f05772784463faf20ad97f433010d_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointNineFivePercentNotesDue2041Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i1175ce0d1778434ab2f82d1aeb58bf2e_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointOneFivePercentNotesDue2041Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="iad10456565dc49e7bc078124e8cd8fe1_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointOneFivePercentNotesDue2041Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ia5815daee6a4476eba6259b8d47fe654_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointSixFivePercentNotesDue2042Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i5dfbce0b73c242c8baa5ce827dad9a2c_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointSixFivePercentNotesDue2042Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="if7316ee9f235452f8616207596971771_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointThreeSevenFivePercentNotesDue2043Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i1675c34a9e9f402db5c00ceb852bb0b6_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointThreeSevenFivePercentNotesDue2043Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i0fd6f6c0e19b45a0b4db95bced8c11a2_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i93a7eb973f5245969d84a7be7e597722_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ied462f3ca0734341b45ec582dc99c7cf_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i3a969d07d31f43ee8b8793eb8498e57b_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i27a15eba71944c9f9d27a09b187b5445_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointThreeSevenFivePercentNotesDue2050Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="if178d7d786ea47c094645c6a4aac66f9_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ThreePointThreeSevenFivePercentNotesDue2050Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="iceaad247ba05416ca273ec699ead3eb8_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i36d572d0be7b4f45b4a95c96ad590314_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i2471f208310742da8d39936484269aa5_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:A300NotesDue20523002052NotesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="iabc69f9b3f0d4959883895ba0b604099_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:A300NotesDue20523002052NotesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="iab6eca48d1b2444986c10a3c8b80b044_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="if155164e9eda4b7494a946338f4c79fb_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i33b3f55471c04aefa2d6d4d4486a0ee1_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OtherNotesDue2097Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i98d314d0c5ac49429ee3c71c38d086dc_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OtherNotesDue2097Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i33a19bf9151948efb174bed3a79387f0_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ifc54ee979f3c450d94595dd648269176_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointSixFivePercent2028NotesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="id79db748ed1c48398fe671a31ee535e0_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointZeroPercent2032NotesMemberMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ie5587a9964dd43d2a6782cd812ea6608_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointEightZeroPercent2041NotesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ic6452876c4b84f979e9f7d07007ec855_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:A300NotesDue20523002052NotesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ia312c6387bbf40488704796f2339d92c_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:RangeAxis">srt:MinimumMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:DebtSecuritiesPayableMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ic5275f5bc2cf4d60a35166b9ec79a4c2_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:RangeAxis">srt:MaximumMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:DebtSecuritiesPayableMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i434c36284fce4b0fb4ec413faf8330f4_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointFourFivePercentNotesDue2030Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:VariableRateAxis">us-gaap:LondonInterbankOfferedRateLIBORMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i4eb0394fe4684ccdb9a301bd5115028c_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPointThreeZeroPercentNotesDue2031Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:LongtermDebtTypeAxis">us-gaap:NotesPayableToBanksMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:VariableRateAxis">us-gaap:LondonInterbankOfferedRateLIBORMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i461e1d1d258d4b4faf9c477a92b85a30_D20210301-20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <startDate>2021-03-01</startDate>
            <endDate>2021-03-31</endDate>
        </period>
    </context>
    <context id="iccfbc695297d4e6b87ea624adb1a3149_D20210901-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <startDate>2021-09-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ib619731edd7541fe8568acd19da059d6_D20210601-20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <startDate>2021-06-01</startDate>
            <endDate>2021-06-30</endDate>
        </period>
    </context>
    <context id="i57518655effb4de5bdcffb7396c85dc7_D20210701-20210731">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-07-31</endDate>
        </period>
    </context>
    <context id="idad3dab92e834ac98e9986b58ed4d7d9_D20201201-20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
        </entity>
        <period>
            <startDate>2020-12-01</startDate>
            <endDate>2020-12-31</endDate>
        </period>
    </context>
    <context id="i0f1af52b3cdc45b69ad881a053131e62_D20211001-20211031">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:SubsequentEventTypeAxis">us-gaap:SubsequentEventMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-01</startDate>
            <endDate>2021-10-31</endDate>
        </period>
    </context>
    <context id="i9b08bc2a35ad4f1b92f1a9c32d536e07_D20211208-20211208">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:StatementScenarioAxis">srt:ScenarioForecastMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-12-08</startDate>
            <endDate>2021-12-08</endDate>
        </period>
    </context>
    <context id="i770b083713ae40d5abf6f7e80c8202c5_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedTranslationAdjustmentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ic6813714a49c4e1ebb1c7f61614d435a_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i8bf4fb9fc5bc4ef5b53a1d2a4b2dbe24_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="if822d7ae834a4a6cbea8ec7441e99f34_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">amgn:AccumulatedOtherAdjustmentAttributabletoParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ic640b9e0658f45ddb2d1866ae9c0d679_D20210101-20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedTranslationAdjustmentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-03-31</endDate>
        </period>
    </context>
    <context id="i362a946d783d4675a1537219335e1ecf_D20210101-20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-03-31</endDate>
        </period>
    </context>
    <context id="i3490a417c3664ea28df867c0b5b64b99_D20210101-20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-03-31</endDate>
        </period>
    </context>
    <context id="i4f043f0296ab40adbbd000e3a19b8263_D20210101-20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">amgn:AccumulatedOtherAdjustmentAttributabletoParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-03-31</endDate>
        </period>
    </context>
    <context id="i3cb26c116a8243b290d914005b2701d7_I20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedTranslationAdjustmentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-03-31</instant>
        </period>
    </context>
    <context id="i1bc84cd5a4d7427f8ea0603f5c4fab36_I20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-03-31</instant>
        </period>
    </context>
    <context id="i12d709ededf44d88909a52a34d1b6465_I20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-03-31</instant>
        </period>
    </context>
    <context id="i36d381395cab48a3a0a38dacd23b095d_I20210331">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">amgn:AccumulatedOtherAdjustmentAttributabletoParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-03-31</instant>
        </period>
    </context>
    <context id="i77c6d51206434679bcbf62756fdc2646_D20210401-20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedTranslationAdjustmentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-04-01</startDate>
            <endDate>2021-06-30</endDate>
        </period>
    </context>
    <context id="ic28cfd96645b4c7caed54e18d250141a_D20210401-20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-04-01</startDate>
            <endDate>2021-06-30</endDate>
        </period>
    </context>
    <context id="i132b85ef12554699b07d3501175ff54f_D20210401-20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-04-01</startDate>
            <endDate>2021-06-30</endDate>
        </period>
    </context>
    <context id="if0969aa8ef414908986e6dbb1310e704_D20210401-20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">amgn:AccumulatedOtherAdjustmentAttributabletoParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-04-01</startDate>
            <endDate>2021-06-30</endDate>
        </period>
    </context>
    <context id="ia5b73fcb215b4f1fb5f74cc40aac6a12_I20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedTranslationAdjustmentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-06-30</instant>
        </period>
    </context>
    <context id="if425fe5fd2294df9a8d0f639c5037ec9_I20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-06-30</instant>
        </period>
    </context>
    <context id="id85f7578a3bc49ca89f363dce5fb32aa_I20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-06-30</instant>
        </period>
    </context>
    <context id="i0fdb28b3619543a79bc3b17b1cc0a2d4_I20210630">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">amgn:AccumulatedOtherAdjustmentAttributabletoParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-06-30</instant>
        </period>
    </context>
    <context id="ief03f026e49a44918a54a590451e6db3_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedTranslationAdjustmentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i98ef59b24516466ebfc3d73a98308ecf_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i719883141b814809a34bc70ed81e53a0_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i45a15717cb5141c5864e39d52a2a95fc_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">amgn:AccumulatedOtherAdjustmentAttributabletoParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ieede5746b0d64fdbbf75791dacc0ef9d_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedTranslationAdjustmentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i672a17c30f404de680e008be9b6464aa_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i9660b813f8e644d8b66ad3118538f278_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i24a9272b1ce44928aa5b6ba2a3c47e9f_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">amgn:AccumulatedOtherAdjustmentAttributabletoParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i32d3947cf2c945deb867f411799b6962_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i671c24fb8d22406aa2608b0eaf66e7ea_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i605067db02764f2ca67c7def81eb8b61_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i956f0c0215934258b02d8cc62b9f996d_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i774914ff61704f25a808fe591907f07a_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i3bd653c39f1d495b9c484952593554a1_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i66702e11ddcd4d94b4f6a53b4231f09f_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ice9f1dfc8f83445b9b89ebcebe763f1a_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ibd9038c5b623433f87f5b5ece6980092_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i74e3224ed0df4d7b844d1e04f9657708_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="iba01b07f6b98472d83708a5396a4df3b_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i67a805bd27be4c1fb6e4f9f773fd62d8_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i7702c711db32401d9e72b707815b70d5_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="if763cdb48cee4124a55a518d0549ffcd_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ifd7b5626cee240a48eb61b6441030918_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="iee30caa26817491b92bd2d46a5a5214d_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i826a29ed0f7a402ea34f70df227b7521_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i7d76b8e7f94f45cc9e548d9fb2040f2d_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i37882f19b0784eccafabfe836dc51f25_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="if0fb1e0d683243249078c344db9e3287_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ie0b4aff0ec6c41e18c08f8a27f8d35d6_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i9bf07042070142818b2dcc65da76d130_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i1b770f2bad0a458bb80d6080d416e653_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i1b4470fbc2904831b9b368445e211ea4_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i33c195572dca4fbf824c6e47b083ab07_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i63f7d63505ec40e78832bd42bf718996_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i25e32e59bf21440087114ea6114b506b_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="iab7f53e834574888ab2bc9ca340df3f0_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i668050cd480a44d59980ffd4209aa796_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i9d7900fb43d041f4bbfa2d693a513c61_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i222681c138f44598b25427e0b8ccae76_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="idb72f426587a4ec5befa804534b12722_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i25541eb9d6c34199be9b71a30ee0401d_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i9e90f12e90a449639d72687889f2e95a_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ied5df9df96c04c2ba41897fd892ef61f_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="id8e22719623e4f98b17f615c76dbb3bd_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="icef3bcd64f2c4ba38b4e195178b28e0a_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i06db08463971480086be884f8fb2f0d5_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i891c6c71b8e7435ea6af4ad541a9f170_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i905b99ada59844fe9615f05632d936ba_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="id43e4d99182d4a8fa11017c14d8cff33_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i0345015d43454b10b538d7fe7b901fa5_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i7d9048c66277472987f2e5c853ea849f_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="if46f80f8f61a471bbd2f2cd5ffc18024_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ifb485de2ab374debabfd24e341e4d676_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasurySecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ibbe73c36ec8a41f991d38edd0c64bb47_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ib8fabc2c97464ca0bbc9f7eb0a1fce39_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i9c8094c8dc344979833ee0c0a4184c0f_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:USTreasuryBillSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ic99616af30c6481c95e52063cc58aab7_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="id4322deb32b242dc9dc95226e1f24e7a_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i5720d28c85fd42cf9bf79344cb93f92e_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">us-gaap:MoneyMarketFundsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i2dc6f4e8be7843d6aaca2adf5f4c6884_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="id158e2e208fe42f6babb0bf2b8d9c0fd_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i0d6271a8a04b419399a0b38f81c5198f_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FinancialInstrumentAxis">amgn:OtherShortTermInterestBearingSecuritiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ie0f44542e8c740659e299accf3ca4908_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ie342e06932cb4eb09ce0c2794ac21c83_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i54877d697b024c418e4690308061e7d5_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i454c26ac3d9f4433aebd4f00ce56ef66_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i367c35eaeba64e7dacfc5f757575d411_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i5d128d2186654d918c38f7fc1d9b358c_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i17fe29849f934c778d329dd2ac540b0f_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i1f484e76b00143c49d1ffb0c04e1aa31_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i62f678821295404c8ddc6c8b0b67d7e2_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i2cc8acfb8b1c4f2eaf54f3edfd2fca61_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i84e77eb97532442da0b8735429da4ecc_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel1Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ifc9c4b5754af40009253488e23ef0207_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel2Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i69ee586072574a02b0f1bc1f4029919c_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis">us-gaap:FairValueInputsLevel3Member</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i1197e68d9d604430b8ce3c78e941f5f2_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i0d2698f3fe114fea898dbd1bedfa2f5c_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForwardContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i393a4aa6df064753bb52276e7ee04a5d_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForwardContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i7734e6b3c1704f4d8a988d1a61348a77_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i399b619e02804ea2ba1db1e14f9ab716_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:EUR</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ib1e612626d9f43b0b769e555166d81e3_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:USD</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ifc7f48af9c2b4b2681e9bd3d3af61b12_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="iba8a92586e2b4417a662a578f1511b3c_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:CHF</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i850f90a0299d43458bd33796e0371d13_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:USD</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i1ee3b6969d0e47798c3ab0adfa9e44d6_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPercentEuroNotesDueTwoThousandTwentySixMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i3334c66245af46b9a585510eebce55e0_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:EUR</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPercentEuroNotesDueTwoThousandTwentySixMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="if435a46c948846aca4c19571c1f10bc9_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:USD</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:TwoPercentEuroNotesDueTwoThousandTwentySixMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="if10b3957b204438a86f3b2309e56842a_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointFiveZeroPercentPoundSterlingNotesDue2026Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i5e8c12261fc243ddbd412fb565f1b116_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:GBP</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointFiveZeroPercentPoundSterlingNotesDue2026Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i603ad1820fef4e8a8f960404cd15b244_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:USD</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FivePointFiveZeroPercentPoundSterlingNotesDue2026Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="id9403f32bf014bd1a180b462efe73171_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPercentPoundSterlingNotesDue2029Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="iece903822c1c413ba21f23e1a3a8817b_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:GBP</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPercentPoundSterlingNotesDue2029Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="if9749c18ee4d4475925e12e9fb9d6ec4_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:CurrencyAxis">currency:USD</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis">amgn:FourPercentPoundSterlingNotesDue2029Member</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ia82e4d4dd7624199b0b9823339e7521e_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="idfede3337ef54161bc5bd47fd541f5ef_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="icc5c639f364e45baa662901e97a7de40_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i01d039e9716e4293aacd1732c82a9104_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i429f2cf41442431d854b0802e1818b63_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="if6773803670d44b2ae4b1519c9996aac_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i5c44b32339c742969f187797f4ae3956_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="icb1c3e075c0447c0a8d96118c3b1ccc0_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i53af41683cb14e598e98d0cdd138caeb_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i9a23429c3e7047b1be61aaf1c0cd68ff_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i4dfa001ded2a48d2a902aa13f44f8684_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i3253252da82e4f4cb4e51fe1f6a14b85_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentsGainLossByHedgingRelationshipAxis">us-gaap:CashFlowHedgingMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i5d9649b14f6944e6b32f46773afd94df_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i93734d89c57d45e99c00e58787a09f5e_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ifb6251f8399b4dc69935ab1011467098_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="amgn:DerivativeInstrumentNameAxis">amgn:A2030And2021NoteHedgesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i44869b7e4ad641a5bc2667496e4c4b2c_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByLiabilityClassAxis">amgn:LongTermDebtCurrentMaturitiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ia18546e9b5354e3da7193d7dab9c11f3_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByLiabilityClassAxis">amgn:LongTermDebtCurrentMaturitiesMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i040b7e3625734005983b800042806116_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByLiabilityClassAxis">us-gaap:LongTermDebtMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="if82a04ddb1484b4d9d685c69534d60ee_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:FairValueByLiabilityClassAxis">us-gaap:LongTermDebtMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i189a6a6830c84033985ac2eb0166844f_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i84ce59b928bc4625b81e9ba243566b0b_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i44310cb41e2e4aaabf0dc581c8c2c4ea_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i2b29edf642674757a33b45fcec1cc8b4_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="icc69b7bd76f6439ea5993cfe7cab843b_D20210701-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-07-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="i2368706943c748edb9e18c4bf06ef9ad_D20210101-20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-01-01</startDate>
            <endDate>2021-09-30</endDate>
        </period>
    </context>
    <context id="ieccef0ffb45a4fdcbd44c752c16e6068_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i503ef52a14c747cb9fab04a1e85b81d1_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:ProductOrServiceAxis">us-gaap:ProductMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="iaef608c4412a4e94ba0fb53cc211b333_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i1da13ce0b09e46ae9200663802380083_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis">us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis">us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i7c59c26b885d420cbebeaff7c5823719_D20200701-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-07-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="ife3621a3597c4b819c57657a0cacdc1d_D20200101-20200930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2020-01-01</startDate>
            <endDate>2020-09-30</endDate>
        </period>
    </context>
    <context id="i6967f808be0e42dd8d431bf91fbf8fda_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForwardContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:NondesignatedMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="icf8902c539da490aa8f154995bfad656_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForwardContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:NondesignatedMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i3847de63b915449dacb3fe5ac480d2d4_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:OtherCurrentNoncurrentAssetsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i6dd8345dd5db4bef839be567148829c8_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:AccruedLiabilitiesOtherNonCurrentLiabilitiesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i66933df39b94465f8542b2c374051858_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:OtherCurrentNoncurrentAssetsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="iae17d6c368384d6081046e9199b88942_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:AccruedLiabilitiesOtherNonCurrentLiabilitiesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i6dc0acd554d1417d8ee9828564a05a4d_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:OtherCurrentNoncurrentAssetsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="id9f3f0d26a574ed0a5c0ee09137be2a1_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:AccruedLiabilitiesOtherNonCurrentLiabilitiesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="ic5f888563c394d598153a924bfacbca4_I20210930">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-09-30</instant>
        </period>
    </context>
    <context id="i78df11bae6c9411f901b63b66ef4b7d7_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:OtherCurrentNoncurrentAssetsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i03f545cb57bd498bb5e65da04d641b83_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:AccruedLiabilitiesOtherNonCurrentLiabilitiesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:ForeignExchangeContractMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ie0dc252346c94bbc92e44b537f39ccd3_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:OtherCurrentNoncurrentAssetsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i91c7206f80d44590a0419f271b3f7a9e_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:AccruedLiabilitiesOtherNonCurrentLiabilitiesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">amgn:CrossCurrencySwapContractsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i44a11e7c427b47569c640463a3089cf8_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:OtherCurrentNoncurrentAssetsMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="ide90c3477b63435f97b32f9aba190c02_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BalanceSheetLocationAxis">amgn:AccruedLiabilitiesOtherNonCurrentLiabilitiesMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:DerivativeInstrumentRiskAxis">us-gaap:InterestRateSwapMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i76a5a06206924308b632f5ca3c34bd97_I20201231">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:HedgingDesignationAxis">us-gaap:DesignatedAsHedgingInstrumentMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2020-12-31</instant>
        </period>
    </context>
    <context id="i2cc9eff2f67a40c98702116571cdb627_D20210928-20210928">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:LitigationCaseAxis">amgn:OtezlaANDAPatentLitigationMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-09-28</startDate>
            <endDate>2021-09-28</endDate>
        </period>
    </context>
    <context id="idaf73178159c45d5ba7f7dde88688204_D20211012-20211012">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:LitigationCaseAxis">amgn:OtezlaANDAPatentLitigationMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsequentEventTypeAxis">us-gaap:SubsequentEventMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-12</startDate>
            <endDate>2021-10-12</endDate>
        </period>
    </context>
    <context id="i7e4af91b19174262910dae2ac9317e09_I20211026">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="srt:LitigationCaseAxis">amgn:NovartisPharmaAGMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsequentEventTypeAxis">us-gaap:SubsequentEventMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-10-26</instant>
        </period>
    </context>
    <context id="i7b7289e4de274a45a8d257b031b3ad23_D20211019-20211019">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:TeneobioIncMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsequentEventTypeAxis">us-gaap:SubsequentEventMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <startDate>2021-10-19</startDate>
            <endDate>2021-10-19</endDate>
        </period>
    </context>
    <context id="i83f84ec51bef4ffe9c7bfc9f4c177613_I20211019">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0000318154</identifier>
            <segment>
                <xbrldi:explicitMember dimension="us-gaap:BusinessAcquisitionAxis">amgn:TeneobioIncMember</xbrldi:explicitMember>
                <xbrldi:explicitMember dimension="us-gaap:SubsequentEventTypeAxis">us-gaap:SubsequentEventMember</xbrldi:explicitMember>
            </segment>
        </entity>
        <period>
            <instant>2021-10-19</instant>
        </period>
    </context>
    <unit id="shares">
        <measure>shares</measure>
    </unit>
    <unit id="usd">
        <measure>iso4217:USD</measure>
    </unit>
    <unit id="usdPerShare">
        <divide>
            <unitNumerator>
                <measure>iso4217:USD</measure>
            </unitNumerator>
            <unitDenominator>
                <measure>shares</measure>
            </unitDenominator>
        </divide>
    </unit>
    <unit id="segment">
        <measure>amgn:segment</measure>
    </unit>
    <unit id="number">
        <measure>pure</measure>
    </unit>
    <unit id="eur">
        <measure>iso4217:EUR</measure>
    </unit>
    <unit id="chf">
        <measure>iso4217:CHF</measure>
    </unit>
    <unit id="gbp">
        <measure>iso4217:GBP</measure>
    </unit>
    <unit id="patent">
        <measure>amgn:patent</measure>
    </unit>
    <unit id="claim">
        <measure>amgn:claim</measure>
    </unit>
    <dei:EntityCentralIndexKey
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80L2ZyYWc6NTgwMmNmMDJkMTM4NDg3ZWJmNDg2NDU2MGNiYjcyNGIvdGFibGU6YWI4YjQzYzVhOGZlNDIzNGIzOTk3Njc2OWY1MmQyYzQvdGFibGVyYW5nZTphYjhiNDNjNWE4ZmU0MjM0YjM5OTc2NzY5ZjUyZDJjNF8yLTEtMS0xLTA_a259e83e-1971-42a8-944f-101c820bef02">0000318154</dei:EntityCentralIndexKey>
    <dei:AmendmentFlag
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80L2ZyYWc6NTgwMmNmMDJkMTM4NDg3ZWJmNDg2NDU2MGNiYjcyNGIvdGFibGU6YWI4YjQzYzVhOGZlNDIzNGIzOTk3Njc2OWY1MmQyYzQvdGFibGVyYW5nZTphYjhiNDNjNWE4ZmU0MjM0YjM5OTc2NzY5ZjUyZDJjNF8zLTEtMS0xLTA_b289863b-5dce-449f-baa8-fb48283e794a">false</dei:AmendmentFlag>
    <dei:DocumentFiscalYearFocus
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80L2ZyYWc6NTgwMmNmMDJkMTM4NDg3ZWJmNDg2NDU2MGNiYjcyNGIvdGFibGU6YWI4YjQzYzVhOGZlNDIzNGIzOTk3Njc2OWY1MmQyYzQvdGFibGVyYW5nZTphYjhiNDNjNWE4ZmU0MjM0YjM5OTc2NzY5ZjUyZDJjNF81LTEtMS0xLTU0MTIy_2838faf5-3e6f-457b-b16c-d9137b17e940">2021</dei:DocumentFiscalYearFocus>
    <dei:DocumentFiscalPeriodFocus
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80L2ZyYWc6NTgwMmNmMDJkMTM4NDg3ZWJmNDg2NDU2MGNiYjcyNGIvdGFibGU6YWI4YjQzYzVhOGZlNDIzNGIzOTk3Njc2OWY1MmQyYzQvdGFibGVyYW5nZTphYjhiNDNjNWE4ZmU0MjM0YjM5OTc2NzY5ZjUyZDJjNF81LTEtMS0xLTA_7639efbf-99c5-416f-bfb6-5c0f4255e294">Q3</dei:DocumentFiscalPeriodFocus>
    <dei:CurrentFiscalYearEndDate
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80L2ZyYWc6NTgwMmNmMDJkMTM4NDg3ZWJmNDg2NDU2MGNiYjcyNGIvdGFibGU6YWI4YjQzYzVhOGZlNDIzNGIzOTk3Njc2OWY1MmQyYzQvdGFibGVyYW5nZTphYjhiNDNjNWE4ZmU0MjM0YjM5OTc2NzY5ZjUyZDJjNF82LTEtMS0xLTA_b43fb2e1-fba2-4961-a541-d1237c96ee9e">--12-31</dei:CurrentFiscalYearEndDate>
    <dei:DocumentType
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODcy_5098ae13-da97-40d3-ad90-a48852a8e5d7">10-Q</dei:DocumentType>
    <dei:DocumentQuarterlyReport
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6MTE1MDBkOGNhMjk2NDkyM2JiMjhlMDg1MGFhZmViOTAvdGFibGVyYW5nZToxMTUwMGQ4Y2EyOTY0OTIzYmIyOGUwODUwYWFmZWI5MF8wLTAtMS0xLTA_b4f7a63f-4a09-4934-ba7f-71d0f4ba271c">true</dei:DocumentQuarterlyReport>
    <dei:DocumentPeriodEndDate
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xMzE_2726dbc7-e341-4dfe-b3ae-1c1a2e96c08f">2021-09-30</dei:DocumentPeriodEndDate>
    <dei:DocumentTransitionReport
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NDJiNThhM2FmN2JhNGRmMjliYWQzYmZjOWMzNzFjOGUvdGFibGVyYW5nZTo0MmI1OGEzYWY3YmE0ZGYyOWJhZDNiZmM5YzM3MWM4ZV8wLTAtMS0xLTA_47b6984e-317a-4d0b-9107-ecd5ab90b666">false</dei:DocumentTransitionReport>
    <dei:EntityFileNumber
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODc0_d381cec3-e9eb-40eb-a35e-747b999cc1d3">001-37702</dei:EntityFileNumber>
    <dei:EntityRegistrantName
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODY3_1644b52f-680a-4ff8-ba46-75eae265b7e2">Amgen Inc.</dei:EntityRegistrantName>
    <dei:EntityIncorporationStateCountryCode
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6MWNlNWIyMTRkYWNiNGI5YWJkYjA5NDU3NDVjNzNlNTIvdGFibGVyYW5nZToxY2U1YjIxNGRhY2I0YjlhYmRiMDk0NTc0NWM3M2U1Ml8wLTAtMS0xLTA_f4263497-edba-4c3c-a703-0199a24e461b">DE</dei:EntityIncorporationStateCountryCode>
    <dei:EntityTaxIdentificationNumber
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6MWNlNWIyMTRkYWNiNGI5YWJkYjA5NDU3NDVjNzNlNTIvdGFibGVyYW5nZToxY2U1YjIxNGRhY2I0YjlhYmRiMDk0NTc0NWM3M2U1Ml8wLTItMS0xLTA_1ed287b7-31d0-467e-a965-882cce569bc3">95-3540776</dei:EntityTaxIdentificationNumber>
    <dei:EntityAddressAddressLine1
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6MWNlNWIyMTRkYWNiNGI5YWJkYjA5NDU3NDVjNzNlNTIvdGFibGVyYW5nZToxY2U1YjIxNGRhY2I0YjlhYmRiMDk0NTc0NWM3M2U1Ml8zLTAtMS0xLTA_08bd9431-d9b1-43be-b6e6-df1e33fce189">One Amgen Center Drive</dei:EntityAddressAddressLine1>
    <dei:EntityAddressPostalZipCode
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6MWNlNWIyMTRkYWNiNGI5YWJkYjA5NDU3NDVjNzNlNTIvdGFibGVyYW5nZToxY2U1YjIxNGRhY2I0YjlhYmRiMDk0NTc0NWM3M2U1Ml8zLTItMS0xLTA_faddb23d-08c4-4492-acbe-63d97e1ae11a">91320-1799</dei:EntityAddressPostalZipCode>
    <dei:EntityAddressCityOrTown
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6MWNlNWIyMTRkYWNiNGI5YWJkYjA5NDU3NDVjNzNlNTIvdGFibGVyYW5nZToxY2U1YjIxNGRhY2I0YjlhYmRiMDk0NTc0NWM3M2U1Ml80LTAtMS0xLTA_6a5786cc-25b9-4569-9751-ad6c9ac4308a">Thousand Oaks</dei:EntityAddressCityOrTown>
    <dei:EntityAddressStateOrProvince
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6MWNlNWIyMTRkYWNiNGI5YWJkYjA5NDU3NDVjNzNlNTIvdGFibGVyYW5nZToxY2U1YjIxNGRhY2I0YjlhYmRiMDk0NTc0NWM3M2U1Ml81LTAtMS0xLTA_348e16ae-507f-44da-8eb2-a9b4d3fb96af">CA</dei:EntityAddressStateOrProvince>
    <dei:CityAreaCode
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODY4_42af7afd-fbcd-40b2-ad8f-ad5076b49529">805</dei:CityAreaCode>
    <dei:LocalPhoneNumber
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODY5_1872a273-8fb7-412f-9c18-dd2564d33d13">447-1000</dei:LocalPhoneNumber>
    <dei:Security12bTitle
      contextRef="i0be1039089ac48b9949c7220072783f8_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8xLTAtMS0xLTA_c7c82290-2911-4168-b52c-96db3934e996">Common stock, $0.0001 par value</dei:Security12bTitle>
    <dei:TradingSymbol
      contextRef="i0be1039089ac48b9949c7220072783f8_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8xLTEtMS0xLTA_fd9aaf25-a6c0-40bf-928a-ac64d8c8578c">AMGN</dei:TradingSymbol>
    <dei:SecurityExchangeName
      contextRef="i0be1039089ac48b9949c7220072783f8_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8xLTItMS0xLTA_3482e6ef-9ea0-4d90-b937-b9114eed53c0">NASDAQ</dei:SecurityExchangeName>
    <dei:Security12bTitle
      contextRef="i7aae778309b84991a0bcd8e16938fcf6_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8yLTAtMS0xLTA_f7972174-e3b3-4712-84f6-6b6fede80040">1.250% Senior Notes due 2022</dei:Security12bTitle>
    <dei:TradingSymbol
      contextRef="i7aae778309b84991a0bcd8e16938fcf6_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8yLTEtMS0xLTA_b2ae11ba-f914-4006-a201-99662cca82c4">AMGN22</dei:TradingSymbol>
    <dei:SecurityExchangeName
      contextRef="i7aae778309b84991a0bcd8e16938fcf6_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8yLTItMS0xLTA_5985b67f-6cb6-4c4d-b1d6-f54cb6d18689">NASDAQ</dei:SecurityExchangeName>
    <dei:Security12bTitle
      contextRef="if48b7c2672244974ae505e9c06ea1da9_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8zLTAtMS0xLTA_8a806c17-1a3f-44b0-ab8b-0626dabf4a49">2.00% Senior Notes due 2026</dei:Security12bTitle>
    <dei:TradingSymbol
      contextRef="if48b7c2672244974ae505e9c06ea1da9_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8zLTEtMS0xLTA_614973cf-0dc2-438e-98dd-e79245cdb9d1">AMGN26</dei:TradingSymbol>
    <dei:SecurityExchangeName
      contextRef="if48b7c2672244974ae505e9c06ea1da9_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6NTVkNjBhNjIyYzkzNDIzMzg0ODBlOWM1MzQ3OGFiYWEvdGFibGVyYW5nZTo1NWQ2MGE2MjJjOTM0MjMzODQ4MGU5YzUzNDc4YWJhYV8zLTItMS0xLTA_fb6d0664-2a1a-4003-8f1e-f95efb14ad86">NASDAQ</dei:SecurityExchangeName>
    <dei:EntityCurrentReportingStatus
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODc1_b06e80d0-1b3f-4339-8d22-31b2dc23dda6">Yes</dei:EntityCurrentReportingStatus>
    <dei:EntityInteractiveDataCurrent
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODc2_e38573d7-707d-482a-9c50-5d41f843e500">Yes</dei:EntityInteractiveDataCurrent>
    <dei:EntityFilerCategory
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6M2Y4Mjk2MzgzMGUwNDc4ZWFkNGE3NjdjNzliN2YzYzgvdGFibGVyYW5nZTozZjgyOTYzODMwZTA0NzhlYWQ0YTc2N2M3OWI3ZjNjOF8wLTAtMS0xLTA_1e4c7208-7897-4684-aa47-bf7b4bdee48a">Large Accelerated Filer</dei:EntityFilerCategory>
    <dei:EntitySmallBusiness
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6M2Y4Mjk2MzgzMGUwNDc4ZWFkNGE3NjdjNzliN2YzYzgvdGFibGVyYW5nZTozZjgyOTYzODMwZTA0NzhlYWQ0YTc2N2M3OWI3ZjNjOF8xLTEtMS0xLTA_a579792c-b6af-465b-971d-9ac121080a94">false</dei:EntitySmallBusiness>
    <dei:EntityEmergingGrowthCompany
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGFibGU6M2Y4Mjk2MzgzMGUwNDc4ZWFkNGE3NjdjNzliN2YzYzgvdGFibGVyYW5nZTozZjgyOTYzODMwZTA0NzhlYWQ0YTc2N2M3OWI3ZjNjOF8xLTMtMS0xLTA_9ba691c7-9a63-45a3-9da9-c45b3f0755f0">false</dei:EntityEmergingGrowthCompany>
    <dei:EntityShellCompany
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODcw_6279dec5-86ed-4e6c-bea2-5b2700e52c53">false</dei:EntityShellCompany>
    <dei:EntityCommonStockSharesOutstanding
      contextRef="id260522a4d634e208edb416383a7443e_I20211028"
      decimals="0"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xL2ZyYWc6NWQ3NDE5OTliZDU5NGQ3MWI1NTUzMGE5OThhNGY4ZDEvdGV4dHJlZ2lvbjo1ZDc0MTk5OWJkNTk0ZDcxYjU1NTMwYTk5OGE0ZjhkMV8xODEw_2c134a1d-cc84-4174-b22a-689e66b99df2"
      unitRef="shares">563265902</dei:EntityCommonStockSharesOutstanding>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i237db287808149dc88791dd0402e8c8d_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMy0xLTEtMS0w_ff29ea1e-ea60-4f6a-8628-3606bbd07914"
      unitRef="usd">6320000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="icc3aae43096e4ee2941dfecfdc9776ad_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMy0zLTEtMS0w_5c20c93e-45a0-43e1-aad8-369b7e18c3c6"
      unitRef="usd">6104000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i3eb445431b634cc6b3e61727cef7b877_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMy01LTEtMS0w_16c8f25e-7b9e-4696-8116-e3fe10888409"
      unitRef="usd">18026000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i556e038dae96477cbe84bc1653ed5883_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMy03LTEtMS0w_533cab51-3c88-4291-849e-212c66973fdb"
      unitRef="usd">17906000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i488eb65c564543e1895d64ea848f40c4_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNC0xLTEtMS0w_29185add-a4c6-49ea-ae8c-145a10a45d76"
      unitRef="usd">386000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="id0ffdac343f944aaa636865f0a68567e_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNC0zLTEtMS0w_36dab01a-0276-46b5-af94-aad9417b485c"
      unitRef="usd">319000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="iddf8eed0ade74615b203cae47895e098_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNC01LTEtMS0w_c64cd7a6-5ec6-46b1-9574-3ac1388b7074"
      unitRef="usd">1107000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ia3ba4d704ab343159b80e5ecde0bf68b_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNC03LTEtMS0w_82599f48-6b55-4fa9-b5a7-a463434ea4b0"
      unitRef="usd">884000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNS0xLTEtMS0w_b31f25e4-2219-4fb8-aeaa-a67074be9667"
      unitRef="usd">6706000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNS0zLTEtMS0w_76d26fb3-3a06-4d8a-b7f7-8536d4465afe"
      unitRef="usd">6423000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNS01LTEtMS0w_d0faca0a-01ab-416c-ac76-59666dfc7b98"
      unitRef="usd">19133000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfNS03LTEtMS0w_e59f4cda-bb20-46b9-b3b3-87095ce5930d"
      unitRef="usd">18790000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:CostOfGoodsAndServicesSold
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOC0xLTEtMS0w_7512a45b-dfe7-4df3-8f78-bc4f4307cb8c"
      unitRef="usd">1609000000</us-gaap:CostOfGoodsAndServicesSold>
    <us-gaap:CostOfGoodsAndServicesSold
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOC0zLTEtMS0w_30704ad1-73a3-4140-9e35-f55e80205e6e"
      unitRef="usd">1561000000</us-gaap:CostOfGoodsAndServicesSold>
    <us-gaap:CostOfGoodsAndServicesSold
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOC01LTEtMS0w_a2870e92-906b-4aac-ad35-94e773e3cada"
      unitRef="usd">4736000000</us-gaap:CostOfGoodsAndServicesSold>
    <us-gaap:CostOfGoodsAndServicesSold
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOC03LTEtMS0w_d162c859-e3e3-4335-90f2-9f72acb32d9b"
      unitRef="usd">4562000000</us-gaap:CostOfGoodsAndServicesSold>
    <us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOS0xLTEtMS0w_5b1aa03f-7cba-42c6-af35-0b203e732e3c"
      unitRef="usd">1422000000</us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost>
    <us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOS0zLTEtMS0w_95f42a84-073c-4742-9ec5-aa82f0817deb"
      unitRef="usd">1062000000</us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost>
    <us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOS01LTEtMS0w_29436589-8c4b-4748-b7bd-db1121f2c67a"
      unitRef="usd">3471000000</us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost>
    <us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfOS03LTEtMS0w_444901cc-a9ed-4af0-b63e-4d1263d99455"
      unitRef="usd">2978000000</us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost>
    <us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTAtMS0xLTEtMA_619dbd92-9f7d-450e-850b-847e6f6d0fe3"
      unitRef="usd">0</us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff>
    <us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTAtMy0xLTEtMA_f1033f78-c365-42c1-8e13-3627c300a547"
      unitRef="usd">0</us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff>
    <us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTAtNS0xLTEtMA_39afd2c4-419f-4dd1-851d-0b178deb69ae"
      unitRef="usd">1505000000</us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff>
    <us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTAtNy0xLTEtMA_ec4b80ce-3138-4d55-882d-936a60e7dfd9"
      unitRef="usd">0</us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff>
    <us-gaap:SellingGeneralAndAdministrativeExpense
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTEtMS0xLTEtMA_5c590541-afe8-4403-87e6-5d3b424e415b"
      unitRef="usd">1305000000</us-gaap:SellingGeneralAndAdministrativeExpense>
    <us-gaap:SellingGeneralAndAdministrativeExpense
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTEtMy0xLTEtMA_0ca0f98b-6730-4907-9027-c999fd5c6e31"
      unitRef="usd">1346000000</us-gaap:SellingGeneralAndAdministrativeExpense>
    <us-gaap:SellingGeneralAndAdministrativeExpense
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTEtNS0xLTEtMA_edb1b611-75a5-42d9-8965-dc0a7a49f6e4"
      unitRef="usd">3943000000</us-gaap:SellingGeneralAndAdministrativeExpense>
    <us-gaap:SellingGeneralAndAdministrativeExpense
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTEtNy0xLTEtMA_05fbfad3-902b-4138-8311-55d6e1ad3f6e"
      unitRef="usd">3957000000</us-gaap:SellingGeneralAndAdministrativeExpense>
    <us-gaap:OtherGeneralExpense
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTItMS0xLTEtMA_6da49cd1-95ec-4b1e-bbf2-e014d087f8d5"
      unitRef="usd">-8000000</us-gaap:OtherGeneralExpense>
    <us-gaap:OtherGeneralExpense
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTItMy0xLTEtMA_3a45fffe-879b-49fb-acbc-4f204991a519"
      unitRef="usd">1000000</us-gaap:OtherGeneralExpense>
    <us-gaap:OtherGeneralExpense
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTItNS0xLTEtMA_abd6f9db-acdb-4c37-883b-75554f6485c1"
      unitRef="usd">143000000</us-gaap:OtherGeneralExpense>
    <us-gaap:OtherGeneralExpense
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTItNy0xLTEtMA_4cf71ccc-8d70-4cd4-b9af-a61c2738725b"
      unitRef="usd">162000000</us-gaap:OtherGeneralExpense>
    <us-gaap:CostsAndExpenses
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTMtMS0xLTEtMA_08d16305-1ab2-437e-8653-1ee80bab1469"
      unitRef="usd">4328000000</us-gaap:CostsAndExpenses>
    <us-gaap:CostsAndExpenses
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTMtMy0xLTEtMA_ae247b7b-84de-408e-8259-3128764beb35"
      unitRef="usd">3970000000</us-gaap:CostsAndExpenses>
    <us-gaap:CostsAndExpenses
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTMtNS0xLTEtMA_1a5b8aff-f418-40c5-8ac7-724c4d507754"
      unitRef="usd">13798000000</us-gaap:CostsAndExpenses>
    <us-gaap:CostsAndExpenses
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTMtNy0xLTEtMA_f8db8374-e08a-4102-868e-8cbc135436d2"
      unitRef="usd">11659000000</us-gaap:CostsAndExpenses>
    <us-gaap:OperatingIncomeLoss
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTUtMS0xLTEtMA_cef5b2e8-7bed-4f11-ae48-4525779c7ecb"
      unitRef="usd">2378000000</us-gaap:OperatingIncomeLoss>
    <us-gaap:OperatingIncomeLoss
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTUtMy0xLTEtMA_6d69ae4c-1238-4905-b279-e76f9d64da23"
      unitRef="usd">2453000000</us-gaap:OperatingIncomeLoss>
    <us-gaap:OperatingIncomeLoss
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTUtNS0xLTEtMA_17c9b1e3-7874-4f79-958e-187496ccddd6"
      unitRef="usd">5335000000</us-gaap:OperatingIncomeLoss>
    <us-gaap:OperatingIncomeLoss
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTUtNy0xLTEtMA_225a927c-a681-47a1-86bc-4ff84ceb57ba"
      unitRef="usd">7131000000</us-gaap:OperatingIncomeLoss>
    <us-gaap:InterestExpenseDebt
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTgtMS0xLTEtMA_e905e146-0842-4819-9fd2-1b1f94b8ca02"
      unitRef="usd">296000000</us-gaap:InterestExpenseDebt>
    <us-gaap:InterestExpenseDebt
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTgtMy0xLTEtMA_5f2f6be6-a138-4301-85c6-cad8fd6e850e"
      unitRef="usd">302000000</us-gaap:InterestExpenseDebt>
    <us-gaap:InterestExpenseDebt
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTgtNS0xLTEtMA_63b5be27-febf-4544-867a-d58acb0a4c6c"
      unitRef="usd">862000000</us-gaap:InterestExpenseDebt>
    <us-gaap:InterestExpenseDebt
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTgtNy0xLTEtMA_ef77d121-0960-4a4b-904a-ec3db8c8325e"
      unitRef="usd">944000000</us-gaap:InterestExpenseDebt>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTktMS0xLTEtMA_50f25787-f8b7-4286-9223-104aac7a2f6a"
      unitRef="usd">73000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTktMy0xLTEtMA_fc7c6426-e226-4770-a569-b617c3f6a612"
      unitRef="usd">55000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTktNS0xLTEtMA_a6b453ed-7e85-4974-b7c2-ea074d62dfe9"
      unitRef="usd">97000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMTktNy0xLTEtMA_aaa5c8a8-3684-4790-8977-73e23e7a0b08"
      unitRef="usd">69000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjEtMS0xLTEtMA_032f8411-1800-42b6-9873-3a8b3ab88382"
      unitRef="usd">2155000000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjEtMy0xLTEtMA_e3972ed9-e23c-450c-af31-acf2891edad3"
      unitRef="usd">2206000000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjEtNS0xLTEtMA_802ee86c-47d4-4c0d-8ba0-0c65caaec3ca"
      unitRef="usd">4570000000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjEtNy0xLTEtMA_31941506-162a-43cf-aaaf-b9ec30ee0531"
      unitRef="usd">6256000000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjMtMS0xLTEtMA_10b83845-ca5c-4148-9a2a-a45ff9491c02"
      unitRef="usd">271000000</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjMtMy0xLTEtMA_5ef2bb2e-949f-4937-b927-fc6b4c4a5fd1"
      unitRef="usd">185000000</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjMtNS0xLTEtMA_8c158659-09b5-4ffd-b97b-f22cc921cbe8"
      unitRef="usd">576000000</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjMtNy0xLTEtMA_aafef26c-f993-4715-82b8-d2b82f8e857d"
      unitRef="usd">607000000</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:NetIncomeLoss
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjUtMS0xLTEtMA_016e3109-c6c5-43a8-aef9-d6fc35e593a4"
      unitRef="usd">1884000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjUtMy0xLTEtMA_788e49e3-ba25-4e7f-b871-f0d7c44a78c5"
      unitRef="usd">2021000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjUtNS0xLTEtMA_b2da8217-15ee-4eeb-8789-b03afc4c415c"
      unitRef="usd">3994000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjUtNy0xLTEtMA_fcf5024a-0d1e-41d0-9096-a35d9410c2c6"
      unitRef="usd">5649000000</us-gaap:NetIncomeLoss>
    <us-gaap:EarningsPerShareBasic
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjgtMS0xLTEtMA_af6ca99f-3921-4a2c-906f-b3c95cd914b6"
      unitRef="usdPerShare">3.32</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareBasic
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjgtMy0xLTEtMA_14a04564-cb13-4b12-b911-f72482494c0d"
      unitRef="usdPerShare">3.45</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareBasic
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjgtNS0xLTEtMA_38a9a622-df3c-4831-b037-608c9ead27f4"
      unitRef="usdPerShare">6.98</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareBasic
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjgtNy0xLTEtMA_5e4e15e5-c325-4bb8-a88c-77ef967ca7cd"
      unitRef="usdPerShare">9.61</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareDiluted
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjktMS0xLTEtMA_10aa7977-4fef-4802-9668-0cba122ea879"
      unitRef="usdPerShare">3.31</us-gaap:EarningsPerShareDiluted>
    <us-gaap:EarningsPerShareDiluted
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjktMy0xLTEtMA_1d96efe5-e572-40cd-9999-f84804a5619a"
      unitRef="usdPerShare">3.43</us-gaap:EarningsPerShareDiluted>
    <us-gaap:EarningsPerShareDiluted
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjktNS0xLTEtMA_52c2d3a3-8e19-4934-9ce8-2c7d1d6090cc"
      unitRef="usdPerShare">6.93</us-gaap:EarningsPerShareDiluted>
    <us-gaap:EarningsPerShareDiluted
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMjktNy0xLTEtMA_3b864ea6-7687-475f-89e8-f6a21b6ce569"
      unitRef="usdPerShare">9.54</us-gaap:EarningsPerShareDiluted>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzItMS0xLTEtMA_ad16d9f0-7086-44b4-bf05-42784325bfe0"
      unitRef="shares">567000000</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzItMy0xLTEtMA_f477fb3f-36cb-4542-9b45-b8bbee5bbc62"
      unitRef="shares">585000000</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzItNS0xLTEtMA_1a5d64eb-10c8-4adc-b514-2493ff0ce933"
      unitRef="shares">572000000</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzItNy0xLTEtMA_c3d376fa-eb20-4afb-b3dd-986288434de2"
      unitRef="shares">588000000</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzMtMS0xLTEtMA_cbc5ed98-d146-498c-b176-7d5a7ea6f7e4"
      unitRef="shares">570000000</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzMtMy0xLTEtMA_e818a9de-fb1e-4571-a318-31fab4bbb5e6"
      unitRef="shares">589000000</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzMtNS0xLTEtMA_c6a05d1d-ce89-416c-97ab-6af2629ac788"
      unitRef="shares">576000000</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xNi9mcmFnOmZmZjNjYjQxYmZiNjRiZDU4Nzc3OGJhZTU2ZGU1ZjYzL3RhYmxlOjEyNTAzM2M1NmYzMTQxNGQ5MDlhZjI0MjA5NzAwNzIxL3RhYmxlcmFuZ2U6MTI1MDMzYzU2ZjMxNDE0ZDkwOWFmMjQyMDk3MDA3MjFfMzMtNy0xLTEtMA_a967d968-04d4-4628-9d98-fbd3b0b8e29d"
      unitRef="shares">592000000</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:NetIncomeLoss
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfMi0xLTEtMS0w_e3da7c8d-ac98-4e86-9fb9-e0024d20494d"
      unitRef="usd">1884000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfMi0zLTEtMS0w_1ff34e75-a045-439a-a1f9-6e33b6cc1d0b"
      unitRef="usd">2021000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfMi01LTEtMS0w_cdf928ff-1c82-44ca-80ef-02671f90d69a"
      unitRef="usd">3994000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfMi03LTEtMS0w_036cba6f-8fd2-4bec-8054-1fd73d635bcc"
      unitRef="usd">5649000000</us-gaap:NetIncomeLoss>
    <us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNC0xLTEtMS0w_11ea642d-7bcd-478c-8305-45299f16e581"
      unitRef="usd">-35000000</us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent>
    <us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNC0zLTEtMS0w_1785c386-69d5-4ee1-96f8-f52825ea9641"
      unitRef="usd">14000000</us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent>
    <us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNC01LTEtMS0w_de9b864b-2379-496b-9542-80fb930f2cf2"
      unitRef="usd">-60000000</us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent>
    <us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNC03LTEtMS0w_8c3f0bcb-f4df-488b-8b34-9d648971376d"
      unitRef="usd">-41000000</us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNS0xLTEtMS0w_36c5334f-0f6b-4c3e-ba58-2b136d1250c6"
      unitRef="usd">99000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNS0zLTEtMS0w_72bbe74a-8b42-445c-89e7-43014f8f4e4e"
      unitRef="usd">-128000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNS01LTEtMS0w_15abf3ee-19d0-40bc-bbab-af97e98dc240"
      unitRef="usd">241000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNS03LTEtMS0w_c2c4d810-1f8a-4ffa-844f-2df599a035bc"
      unitRef="usd">-305000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent>
    <us-gaap:OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNi0xLTEtMS0w_3bf8de49-872e-42af-9418-b73118a9e9cf"
      unitRef="usd">-1000000</us-gaap:OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent>
    <us-gaap:OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNi0zLTEtMS0w_d817164a-6184-4b29-8d14-f226203076fe"
      unitRef="usd">1000000</us-gaap:OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent>
    <us-gaap:OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNi01LTEtMS0w_d6d0c4d3-85e5-4298-a8d5-68446e4c06d4"
      unitRef="usd">-1000000</us-gaap:OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent>
    <us-gaap:OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNi03LTEtMS0w_c526f443-3519-4722-a881-16f7d143a654"
      unitRef="usd">-20000000</us-gaap:OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent>
    <amgn:OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNy0xLTEtMS0w_df02dd81-165c-422f-a6d1-d5dff7ce0fdb"
      unitRef="usd">-3000000</amgn:OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent>
    <amgn:OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNy0zLTEtMS0w_47637a9a-3f05-4b42-8e3b-02e8f87d5157"
      unitRef="usd">-7000000</amgn:OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent>
    <amgn:OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNy01LTEtMS0w_90eef492-3b49-4d08-9e8c-16f03cd463c1"
      unitRef="usd">-3000000</amgn:OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent>
    <amgn:OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfNy03LTEtMS0w_3bbae791-9e58-4585-b0db-2bf4146c649d"
      unitRef="usd">-9000000</amgn:OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOC0xLTEtMS0w_6840ff1d-7548-4037-aa7c-52e76c31ed31"
      unitRef="usd">60000000</us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOC0zLTEtMS0w_6996e3fe-7253-4a16-bab6-e21c6ff043ee"
      unitRef="usd">-120000000</us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOC01LTEtMS0w_9d1cc307-9877-4f35-97d2-83123cbece41"
      unitRef="usd">177000000</us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOC03LTEtMS0w_07e37f4b-4313-45b8-897a-1f8431fb1be2"
      unitRef="usd">-375000000</us-gaap:OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent>
    <us-gaap:ComprehensiveIncomeNetOfTax
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOS0xLTEtMS0w_32a78785-5d36-4318-b488-bb1abd79ec31"
      unitRef="usd">1944000000</us-gaap:ComprehensiveIncomeNetOfTax>
    <us-gaap:ComprehensiveIncomeNetOfTax
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOS0zLTEtMS0w_88920489-91c2-4f50-9381-8055ccb2827d"
      unitRef="usd">1901000000</us-gaap:ComprehensiveIncomeNetOfTax>
    <us-gaap:ComprehensiveIncomeNetOfTax
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOS01LTEtMS0w_c5a14e3c-6b70-468b-9938-967efc95032e"
      unitRef="usd">4171000000</us-gaap:ComprehensiveIncomeNetOfTax>
    <us-gaap:ComprehensiveIncomeNetOfTax
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xOS9mcmFnOjA5NDJlMTQ0NjVkZTRkMmQ4YWUyNmVmZDRkY2MwYmQ2L3RhYmxlOjVhN2E2MmQ5MjY0ZjQwYzFhMjg0MmIzOWE3MzcyZjVlL3RhYmxlcmFuZ2U6NWE3YTYyZDkyNjRmNDBjMWEyODQyYjM5YTczNzJmNWVfOS03LTEtMS0w_364e87e7-50ae-4a35-aa41-8bf14ebafb3e"
      unitRef="usd">5274000000</us-gaap:ComprehensiveIncomeNetOfTax>
    <us-gaap:CashAndCashEquivalentsAtCarryingValue
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNC0xLTEtMS0w_38b55c79-39df-4f47-aa29-585e80705ecd"
      unitRef="usd">11969000000</us-gaap:CashAndCashEquivalentsAtCarryingValue>
    <us-gaap:CashAndCashEquivalentsAtCarryingValue
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNC0zLTEtMS0w_38692a39-f473-4577-88d9-7507ec510443"
      unitRef="usd">6266000000</us-gaap:CashAndCashEquivalentsAtCarryingValue>
    <us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNS0xLTEtMS0w_61add535-189d-4fb5-a60d-bb6c41c50406"
      unitRef="usd">952000000</us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent>
    <us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNS0zLTEtMS0w_58f8ad69-b851-4976-b87f-a7d3353cd1dd"
      unitRef="usd">4381000000</us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent>
    <us-gaap:AccountsReceivableNetCurrent
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNi0xLTEtMS0w_2b2a1110-275f-4f1b-b518-9ab4e62c47d3"
      unitRef="usd">4765000000</us-gaap:AccountsReceivableNetCurrent>
    <us-gaap:AccountsReceivableNetCurrent
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNi0zLTEtMS0w_1cce1e8e-113e-4131-9cf3-6dd57326ef21"
      unitRef="usd">4525000000</us-gaap:AccountsReceivableNetCurrent>
    <us-gaap:InventoryNet
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNy0xLTEtMS0w_d46b3cf8-e476-4242-900a-297cd92fc47f"
      unitRef="usd">4152000000</us-gaap:InventoryNet>
    <us-gaap:InventoryNet
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfNy0zLTEtMS0w_871a5322-7542-4e6f-9fc0-80deae96bde4"
      unitRef="usd">3893000000</us-gaap:InventoryNet>
    <us-gaap:OtherAssetsCurrent
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfOC0xLTEtMS0w_c8dc15bc-186e-4383-a6b5-e447c97c93eb"
      unitRef="usd">2542000000</us-gaap:OtherAssetsCurrent>
    <us-gaap:OtherAssetsCurrent
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfOC0zLTEtMS0w_923cc3f1-d034-46d4-bd3c-15136e0f1548"
      unitRef="usd">2079000000</us-gaap:OtherAssetsCurrent>
    <us-gaap:AssetsCurrent
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfOS0xLTEtMS0w_dadc3666-4bd4-4cc6-b5f6-204801bb714a"
      unitRef="usd">24380000000</us-gaap:AssetsCurrent>
    <us-gaap:AssetsCurrent
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfOS0zLTEtMS0w_611c5216-0dcc-4b59-aef0-bb1907ff66ba"
      unitRef="usd">21144000000</us-gaap:AssetsCurrent>
    <us-gaap:PropertyPlantAndEquipmentNet
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTEtMS0xLTEtMA_f96e452d-d9d9-44a5-81e6-c01317eadf34"
      unitRef="usd">4982000000</us-gaap:PropertyPlantAndEquipmentNet>
    <us-gaap:PropertyPlantAndEquipmentNet
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTEtMy0xLTEtMA_be08ef93-7ac9-4086-aabd-a49d21a90dcc"
      unitRef="usd">4889000000</us-gaap:PropertyPlantAndEquipmentNet>
    <us-gaap:IntangibleAssetsNetExcludingGoodwill
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTItMS0xLTEtMA_ee9e8019-162d-4205-bcb8-0252c385d70a"
      unitRef="usd">14659000000</us-gaap:IntangibleAssetsNetExcludingGoodwill>
    <us-gaap:IntangibleAssetsNetExcludingGoodwill
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTItMy0xLTEtMA_d36f4fce-0b4c-4cea-a773-7e7148d9394a"
      unitRef="usd">16587000000</us-gaap:IntangibleAssetsNetExcludingGoodwill>
    <us-gaap:Goodwill
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTMtMS0xLTEtMA_16385a6c-ba2c-47e9-b20f-f2505c6c0f53"
      unitRef="usd">14665000000</us-gaap:Goodwill>
    <us-gaap:Goodwill
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTMtMy0xLTEtMA_ff3b5dee-19c9-48c4-9931-1e115180c602"
      unitRef="usd">14689000000</us-gaap:Goodwill>
    <us-gaap:OtherAssetsNoncurrent
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTQtMS0xLTEtMA_ba580bea-1d79-43a9-bf95-51c67da43524"
      unitRef="usd">6307000000</us-gaap:OtherAssetsNoncurrent>
    <us-gaap:OtherAssetsNoncurrent
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTQtMy0xLTEtMA_a343e2bb-137c-4b4b-ae3c-d3c71e233f54"
      unitRef="usd">5639000000</us-gaap:OtherAssetsNoncurrent>
    <us-gaap:Assets
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTUtMS0xLTEtMA_18a84c68-a2e0-4130-907a-664a8419e72b"
      unitRef="usd">64993000000</us-gaap:Assets>
    <us-gaap:Assets
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTUtMy0xLTEtMA_9f796a69-9fa9-498d-a832-1e4916064ce5"
      unitRef="usd">62948000000</us-gaap:Assets>
    <us-gaap:AccountsPayableCurrent
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTktMS0xLTEtMA_628ba315-7186-4c5c-89c0-7c7790989413"
      unitRef="usd">1171000000</us-gaap:AccountsPayableCurrent>
    <us-gaap:AccountsPayableCurrent
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMTktMy0xLTEtMA_e9b2a729-9fb0-4819-9f0f-f745093e1cf4"
      unitRef="usd">1421000000</us-gaap:AccountsPayableCurrent>
    <us-gaap:AccruedLiabilitiesCurrent
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjAtMS0xLTEtMA_dec26657-8bc4-4da0-82c4-37da405bde42"
      unitRef="usd">9383000000</us-gaap:AccruedLiabilitiesCurrent>
    <us-gaap:AccruedLiabilitiesCurrent
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjAtMy0xLTEtMA_8a31aac8-8d1d-489a-bf0c-b98c2001bcf2"
      unitRef="usd">10141000000</us-gaap:AccruedLiabilitiesCurrent>
    <us-gaap:LongTermDebtCurrent
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjEtMS0xLTEtMA_c0a3143e-c4d9-4e16-b5c9-2cbbbec6710f"
      unitRef="usd">4288000000</us-gaap:LongTermDebtCurrent>
    <us-gaap:LongTermDebtCurrent
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjEtMy0xLTEtMA_8eed8da4-c848-429d-b4b9-4f23c0831c7c"
      unitRef="usd">91000000</us-gaap:LongTermDebtCurrent>
    <us-gaap:LiabilitiesCurrent
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjItMS0xLTEtMA_339a9d28-90e0-41e7-af46-5ba41d5ff315"
      unitRef="usd">14842000000</us-gaap:LiabilitiesCurrent>
    <us-gaap:LiabilitiesCurrent
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjItMy0xLTEtMA_8c861cbb-4566-46f2-9de8-8f80640200ec"
      unitRef="usd">11653000000</us-gaap:LiabilitiesCurrent>
    <us-gaap:LongTermDebtNoncurrent
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjQtMS0xLTEtMA_f8a656b5-9c8f-4a72-8b0c-1bbbc298964c"
      unitRef="usd">33291000000</us-gaap:LongTermDebtNoncurrent>
    <us-gaap:LongTermDebtNoncurrent
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjQtMy0xLTEtMA_db958e75-5761-4c96-bff1-38cb3ebe9e04"
      unitRef="usd">32895000000</us-gaap:LongTermDebtNoncurrent>
    <us-gaap:LiabilityForUncertainTaxPositionsNoncurrent
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjUtMS0xLTEtMA_b7444edb-6aae-454a-a80f-8f47156e818b"
      unitRef="usd">6483000000</us-gaap:LiabilityForUncertainTaxPositionsNoncurrent>
    <us-gaap:LiabilityForUncertainTaxPositionsNoncurrent
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjUtMy0xLTEtMA_4033155d-59bb-4ff3-8f2f-cbd3cabd36df"
      unitRef="usd">6968000000</us-gaap:LiabilityForUncertainTaxPositionsNoncurrent>
    <us-gaap:OtherLiabilitiesNoncurrent
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjYtMS0xLTEtMA_03c505e2-133d-49ea-8f8c-5ae2fa554185"
      unitRef="usd">2160000000</us-gaap:OtherLiabilitiesNoncurrent>
    <us-gaap:OtherLiabilitiesNoncurrent
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjYtMy0xLTEtMA_c8ff25b3-d10e-4655-9522-c7e0b3e4e9f8"
      unitRef="usd">2023000000</us-gaap:OtherLiabilitiesNoncurrent>
    <us-gaap:CommitmentsAndContingencies
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjgtMS0xLTEtMA_8f299b4a-1f6b-4b32-90ba-eb5aad33b413"
      unitRef="usd"
      xsi:nil="true"/>
    <us-gaap:CommitmentsAndContingencies
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMjgtMy0xLTEtMA_ee0ffaba-37b0-4a69-9b71-73604e90aeef"
      unitRef="usd"
      xsi:nil="true"/>
    <us-gaap:CommonStockParOrStatedValuePerShare
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMC0xLTEtMC90ZXh0cmVnaW9uOjUzYTE5MGI2NGViMDQxM2Q5MzMxNjZlN2U4NjkzNmEzXzQ5_ddffa4ab-e128-419c-94f3-0196f0dbc161"
      unitRef="usdPerShare">0.0001</us-gaap:CommonStockParOrStatedValuePerShare>
    <us-gaap:CommonStockParOrStatedValuePerShare
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMC0xLTEtMC90ZXh0cmVnaW9uOjUzYTE5MGI2NGViMDQxM2Q5MzMxNjZlN2U4NjkzNmEzXzQ5_dec66248-c364-4409-a559-081228fe4af0"
      unitRef="usdPerShare">0.0001</us-gaap:CommonStockParOrStatedValuePerShare>
    <us-gaap:CommonStockSharesAuthorized
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMC0xLTEtMC90ZXh0cmVnaW9uOjUzYTE5MGI2NGViMDQxM2Q5MzMxNjZlN2U4NjkzNmEzXzYz_700557e7-00d7-49cf-8b2a-62e3a76356fb"
      unitRef="shares">2750000000</us-gaap:CommonStockSharesAuthorized>
    <us-gaap:CommonStockSharesAuthorized
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMC0xLTEtMC90ZXh0cmVnaW9uOjUzYTE5MGI2NGViMDQxM2Q5MzMxNjZlN2U4NjkzNmEzXzYz_8acb803f-00c1-4953-8190-980f2b64a5a8"
      unitRef="shares">2750000000</us-gaap:CommonStockSharesAuthorized>
    <us-gaap:CommonStockSharesOutstanding
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMC0xLTEtMC90ZXh0cmVnaW9uOjUzYTE5MGI2NGViMDQxM2Q5MzMxNjZlN2U4NjkzNmEzXzk3_3673c112-1438-4863-adb0-d7400e68ec17"
      unitRef="shares">565000000.0</us-gaap:CommonStockSharesOutstanding>
    <us-gaap:CommonStockSharesOutstanding
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMC0xLTEtMC90ZXh0cmVnaW9uOjUzYTE5MGI2NGViMDQxM2Q5MzMxNjZlN2U4NjkzNmEzXzExNw_09c687d0-d45d-4de4-b611-2796f6480bcd"
      unitRef="shares">578300000</us-gaap:CommonStockSharesOutstanding>
    <us-gaap:CommonStocksIncludingAdditionalPaidInCapital
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMS0xLTEtMA_07000854-7c12-4e1d-a616-6f53f96f8b4e"
      unitRef="usd">31989000000</us-gaap:CommonStocksIncludingAdditionalPaidInCapital>
    <us-gaap:CommonStocksIncludingAdditionalPaidInCapital
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzEtMy0xLTEtMA_c56f12d6-b22b-45c7-a9b0-0ead682d3b9d"
      unitRef="usd">31802000000</us-gaap:CommonStocksIncludingAdditionalPaidInCapital>
    <us-gaap:RetainedEarningsAccumulatedDeficit
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzItMS0xLTEtMA_53f25641-def1-458f-aba3-3c3a06d65e41"
      unitRef="usd">-22964000000</us-gaap:RetainedEarningsAccumulatedDeficit>
    <us-gaap:RetainedEarningsAccumulatedDeficit
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzItMy0xLTEtMA_8d3731e9-6091-4cf2-a554-9a09946cff5c"
      unitRef="usd">-21408000000</us-gaap:RetainedEarningsAccumulatedDeficit>
    <us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzMtMS0xLTEtMA_16aee6af-9354-4dbf-afcb-7ca9902f4425"
      unitRef="usd">-808000000</us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzMtMy0xLTEtMA_de5d90b4-324b-45ee-be23-9f8cb5a2809d"
      unitRef="usd">-985000000</us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:StockholdersEquity
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzQtMS0xLTEtMA_72c34e55-8b8e-41a1-89eb-671d8173328b"
      unitRef="usd">8217000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzQtMy0xLTEtMA_448f2387-70ec-4242-928c-6bd5d0573175"
      unitRef="usd">9409000000</us-gaap:StockholdersEquity>
    <us-gaap:LiabilitiesAndStockholdersEquity
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzUtMS0xLTEtMA_fcc32715-a9ec-43a3-bc46-9cc0a28852ac"
      unitRef="usd">64993000000</us-gaap:LiabilitiesAndStockholdersEquity>
    <us-gaap:LiabilitiesAndStockholdersEquity
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yMi9mcmFnOjY2NWY1ZGZkMDE5NDRjMTA5ZDdmZTJlMjcwNWY4ODdkL3RhYmxlOmVmODM0NmZmZjkxODQwNWRiNzFmM2E1NDRhY2UyYjZjL3RhYmxlcmFuZ2U6ZWY4MzQ2ZmZmOTE4NDA1ZGI3MWYzYTU0NGFjZTJiNmNfMzUtMy0xLTEtMA_42f2ed98-5c5f-4d19-a36f-5ac4f4e28a9a"
      unitRef="usd">62948000000</us-gaap:LiabilitiesAndStockholdersEquity>
    <us-gaap:CommonStockSharesOutstanding
      contextRef="i091ea451ee5b401e9a692e47a31d079b_I20201231"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMS0xLTEtMS0w_02d3606d-393f-4ec4-90d6-c30e4d1ce9f6"
      unitRef="shares">578300000</us-gaap:CommonStockSharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="i85eb1be2504f43d5b6b300dc199131eb_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMS0zLTEtMS0w_5c27968c-ea84-4d19-8669-98ea84f08344"
      unitRef="usd">31802000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i8fd3f59d080644dfb1308254046fba14_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMS01LTEtMS0w_f6524f96-6e81-4a36-b0e9-86748eae2d9f"
      unitRef="usd">-21408000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="iaea9ac2193424d918f03fbf56ef30362_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMS03LTEtMS0w_53ac440f-c9d6-4268-82f3-83e28a808365"
      unitRef="usd">-985000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMS05LTEtMS0w_841908f0-dd19-4bcb-b38e-deb1a3f48085"
      unitRef="usd">9409000000</us-gaap:StockholdersEquity>
    <us-gaap:NetIncomeLoss
      contextRef="ia7cc3209b62b4e859989adf72041bfb0_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMy01LTEtMS0w_2a83d540-1c6b-4245-ad8b-46e81600c1c1"
      unitRef="usd">1646000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMy05LTEtMS0w_48ee226d-b885-4ad4-a6da-9b91851684d0"
      unitRef="usd">1646000000</us-gaap:NetIncomeLoss>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTax
      contextRef="i8ff5ee6ed2904950abde3e69e298a888_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNC03LTEtMS0w_cb465528-454e-49a1-a120-d13ff656566c"
      unitRef="usd">152000000</us-gaap:OtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTax
      contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNC05LTEtMS0w_cabc0571-6237-4e92-b9ec-680d1297c2ec"
      unitRef="usd">152000000</us-gaap:OtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:CommonStockDividendsPerShareDeclared
      contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNS0wLTEtMS0wL3RleHRyZWdpb246NmI2NjcxOWI2NDEwNGVlNDgxNjg0ODIzNjkxOGU3ZDRfNDE_9109223a-6d0f-4de2-bdcf-4cc4165d1789"
      unitRef="usdPerShare">1.76</us-gaap:CommonStockDividendsPerShareDeclared>
    <us-gaap:DividendsCommonStockCash
      contextRef="ia7cc3209b62b4e859989adf72041bfb0_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNS01LTEtMS0w_d6b13b9e-4205-46db-9588-7d4a7eafdd6c"
      unitRef="usd">1012000000</us-gaap:DividendsCommonStockCash>
    <us-gaap:DividendsCommonStockCash
      contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNS05LTEtMS0w_9b4d8557-c2e8-463d-91d9-6fb8cf931423"
      unitRef="usd">1012000000</us-gaap:DividendsCommonStockCash>
    <us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation
      contextRef="i7969d970f6a54e60804bc95280496c8b_D20210101-20210331"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNi0xLTEtMS0w_112b2527-7d7d-4f84-97f8-b42aab3e3357"
      unitRef="shares">700000</us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation>
    <us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation
      contextRef="i2dcd4eff17124be29dcc8becb0415e77_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNi0zLTEtMS0w_5894f068-c357-4ff6-b15c-ef294e00bf03"
      unitRef="usd">6000000</us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation>
    <us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation
      contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNi05LTEtMS0w_2448cd8a-a8b4-40c1-8f1b-3170a60b59e7"
      unitRef="usd">6000000</us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="i2dcd4eff17124be29dcc8becb0415e77_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNy0zLTEtMS0w_bd2a553d-e226-497c-b61e-41d79dea6bda"
      unitRef="usd">57000000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfNy05LTEtMS0w_39408182-007a-4096-861f-1cb5817f67ab"
      unitRef="usd">57000000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet
      contextRef="i2dcd4eff17124be29dcc8becb0415e77_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfOC0zLTEtMS0w_2e0de5ca-22fc-4d91-8aff-30b3c9e03f96"
      unitRef="usd">-59000000</us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet>
    <us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet
      contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfOC05LTEtMS0w_9a9dda57-b39a-427f-8949-6595709b50b2"
      unitRef="usd">-59000000</us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodShares
      contextRef="i7969d970f6a54e60804bc95280496c8b_D20210101-20210331"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfOS0xLTEtMS0w_8aaca0a4-5481-4f36-a186-eadf56f4d458"
      unitRef="shares">3700000</us-gaap:StockRepurchasedAndRetiredDuringPeriodShares>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodValue
      contextRef="ia7cc3209b62b4e859989adf72041bfb0_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfOS01LTEtMS0w_3f7ab1a9-aced-4d05-8cc5-305c6cb54e22"
      unitRef="usd">865000000</us-gaap:StockRepurchasedAndRetiredDuringPeriodValue>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodValue
      contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfOS05LTEtMS0w_5466f643-71f7-4a17-b4bf-b250f69f564c"
      unitRef="usd">865000000</us-gaap:StockRepurchasedAndRetiredDuringPeriodValue>
    <us-gaap:CommonStockSharesOutstanding
      contextRef="ib60c8e3ee5494c37bc18cec8bd0c619c_I20210331"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTAtMS0xLTEtMA_55fd3402-fbe0-4a86-8485-d77749adf67b"
      unitRef="shares">575300000</us-gaap:CommonStockSharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="i79a13e6805f34de1abc4d45f73bf3010_I20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTAtMy0xLTEtMA_be263d06-5dc4-4e64-92c1-1252085a9d9d"
      unitRef="usd">31806000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="ifd05c4dcf2974888bb7ea94987a2302e_I20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTAtNS0xLTEtMA_45e372f7-607d-4e94-9d81-2add5c83b268"
      unitRef="usd">-21639000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i02d7483a082146bca57a490cca649110_I20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTAtNy0xLTEtMA_8957a366-68b8-4ce0-baa9-6021d5b46636"
      unitRef="usd">-833000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i65ba920729294b6ca0d58b7c3d55da64_I20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTAtOS0xLTEtMA_873c47e9-8c4d-4964-930c-b6efe9927e3d"
      unitRef="usd">9334000000</us-gaap:StockholdersEquity>
    <us-gaap:NetIncomeLoss
      contextRef="i7a34b44a0b684692a8ce01f962435f05_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTItNS0xLTEtMA_fbf543bf-7003-48ee-a46c-d9cdfeba710a"
      unitRef="usd">464000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTItOS0xLTEtMA_61957c05-a602-4a00-86db-7edb36f99d3f"
      unitRef="usd">464000000</us-gaap:NetIncomeLoss>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTax
      contextRef="ic34d84ceeae14872821180cf4d7c1fc9_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTMtNy0xLTEtMA_42015501-5633-4ddb-8847-047e84db6153"
      unitRef="usd">-35000000</us-gaap:OtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTax
      contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTMtOS0xLTEtMA_efc0a28c-261b-4439-aa9b-794ae78efb15"
      unitRef="usd">-35000000</us-gaap:OtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation
      contextRef="ibcaee6c81e1645c98fc9f7046d1c84b0_D20210401-20210630"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTUtMS0xLTEtMA_7e5736e8-fa53-477d-93a5-56a8a6f54a59"
      unitRef="shares">800000</us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation>
    <us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation
      contextRef="i2ed57ff3dbc9401b9e0afd3df0e57952_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTUtMy0xLTEtMA_b852b89c-ca87-45d3-8f94-ee91ee1f74e4"
      unitRef="usd">47000000</us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation>
    <us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation
      contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTUtOS0xLTEtMA_8801a2b9-fc02-4a59-ad06-8bff0af0c834"
      unitRef="usd">47000000</us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="i2ed57ff3dbc9401b9e0afd3df0e57952_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTYtMy0xLTEtMA_9d07ab84-1d18-4a0d-a91d-568ce1327dd5"
      unitRef="usd">100000000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTYtOS0xLTEtMA_aa7fd2c6-957c-4fa1-8240-c2b5d2e6f2a6"
      unitRef="usd">100000000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet
      contextRef="i2ed57ff3dbc9401b9e0afd3df0e57952_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTctMy0xLTEtMA_4c557748-4443-41a1-ba93-d802a3fc2b3e"
      unitRef="usd">-76000000</us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet>
    <us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet
      contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTctOS0xLTEtMA_c369fa61-b9b4-48a9-bbf9-67012992c94a"
      unitRef="usd">-76000000</us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodShares
      contextRef="ibcaee6c81e1645c98fc9f7046d1c84b0_D20210401-20210630"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTgtMS0xLTEtMA_0d4278f3-9b0f-4f07-8e92-e1a186f6e676"
      unitRef="shares">6500000</us-gaap:StockRepurchasedAndRetiredDuringPeriodShares>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodValue
      contextRef="i7a34b44a0b684692a8ce01f962435f05_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTgtNS0xLTEtMA_00dc1319-a58f-4fc8-9f16-0443395c5d13"
      unitRef="usd">1592000000</us-gaap:StockRepurchasedAndRetiredDuringPeriodValue>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodValue
      contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTgtOS0xLTEtMA_dd25a054-471b-41be-814b-aa9835648be4"
      unitRef="usd">1592000000</us-gaap:StockRepurchasedAndRetiredDuringPeriodValue>
    <us-gaap:StockholdersEquityOther
      contextRef="i7a34b44a0b684692a8ce01f962435f05_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTktNS0xLTEtMA_d7746640-c7f1-4e5d-87cc-b262c923b8f0"
      unitRef="usd">5000000</us-gaap:StockholdersEquityOther>
    <us-gaap:StockholdersEquityOther
      contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMTktOS0xLTEtMA_61259cd1-95ec-4346-968a-e74ca7a5cd0d"
      unitRef="usd">5000000</us-gaap:StockholdersEquityOther>
    <us-gaap:CommonStockSharesOutstanding
      contextRef="ib91fd46e082e435c8604678dba5c6807_I20210630"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjAtMS0xLTEtMA_59bf37ac-35c2-4504-928f-7dadd3063794"
      unitRef="shares">569600000</us-gaap:CommonStockSharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="i3ee32787b0ee44f7835a1897d7ccc133_I20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjAtMy0xLTEtMA_1cc20ef0-3c83-4e3c-8b0f-bdd95728fe45"
      unitRef="usd">31877000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="ib9c55bd482c8427c869df819585fe64b_I20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjAtNS0xLTEtMA_27b02754-b190-4268-9721-c6d5cd883602"
      unitRef="usd">-22762000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i9d079f6d807e45a8b0ea7b4bf5ca1b1c_I20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjAtNy0xLTEtMA_e2c427f2-e12c-4abd-8027-5c8e0f897853"
      unitRef="usd">-868000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="ibb4ad07750104a41ad551ce7e97f7afe_I20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjAtOS0xLTEtMA_25d678de-bbae-4a1d-acb9-b333c3b08d18"
      unitRef="usd">8247000000</us-gaap:StockholdersEquity>
    <us-gaap:NetIncomeLoss
      contextRef="i6271ffbf65cf467783eea9a8f4a54fb0_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjItNS0xLTEtMA_841df04b-4906-4c6c-bc4b-1558207f794a"
      unitRef="usd">1884000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjItOS0xLTEtMA_3bcd5da5-95c8-40e0-8387-9856130dbb0b"
      unitRef="usd">1884000000</us-gaap:NetIncomeLoss>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTax
      contextRef="i984e708e2ca94952a077181e38e25d78_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjMtNy0xLTEtMA_69fb9784-08fd-466c-b412-fe2d014432b1"
      unitRef="usd">60000000</us-gaap:OtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTax
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjMtOS0xLTEtMA_619cb7f5-dc49-4e5c-825c-ff9c380ceb01"
      unitRef="usd">60000000</us-gaap:OtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:CommonStockDividendsPerShareDeclared
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjQtMC0xLTEtMC90ZXh0cmVnaW9uOmZhZTNmNmU0YjU5ZjQ5YjBiZTMxZTJlNTMyYTAyZjNlXzQx_cc1e1b10-737f-45a2-a3b6-32d3a51bc32b"
      unitRef="usdPerShare">1.76</us-gaap:CommonStockDividendsPerShareDeclared>
    <us-gaap:DividendsCommonStockCash
      contextRef="i6271ffbf65cf467783eea9a8f4a54fb0_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjQtNS0xLTEtMA_242f7802-922f-4daa-a265-fd6e1f408a3c"
      unitRef="usd">1017000000</us-gaap:DividendsCommonStockCash>
    <us-gaap:DividendsCommonStockCash
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjQtOS0xLTEtMA_42e60471-821c-4d03-be8e-9db30194ad6b"
      unitRef="usd">1017000000</us-gaap:DividendsCommonStockCash>
    <us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation
      contextRef="i967296e305e04ee0ba9de8194bd5c859_D20210701-20210930"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjUtMS0xLTEtMA_f85d447a-ff03-45c9-a47e-df3669fe2e3c"
      unitRef="shares">0</us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation>
    <us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation
      contextRef="ia9f1d012da3a43b89a1c71ec6c7599ff_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjUtMy0xLTEtMA_df9cec2e-05cc-4430-89f5-7ae811b29322"
      unitRef="usd">9000000</us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation>
    <us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjUtOS0xLTEtMA_e9fd6506-4133-49de-a05e-dbb476572308"
      unitRef="usd">9000000</us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="ia9f1d012da3a43b89a1c71ec6c7599ff_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjYtMy0xLTEtMA_56a83445-2979-44a5-8df4-f08f796a7945"
      unitRef="usd">111000000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjYtOS0xLTEtMA_65a7dde2-6b88-4ef4-aefa-af7e8e73974b"
      unitRef="usd">111000000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet
      contextRef="ia9f1d012da3a43b89a1c71ec6c7599ff_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjctMy0xLTEtMA_aea9b38f-8701-4b3e-87a1-0ec3d3ee0995"
      unitRef="usd">-8000000</us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet>
    <us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjctOS0xLTEtMA_4f7de278-4e80-4f53-91e6-028257e8b030"
      unitRef="usd">-8000000</us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodShares
      contextRef="i967296e305e04ee0ba9de8194bd5c859_D20210701-20210930"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjgtMS0xLTEtMA_bddb69c6-1f23-4573-9919-8758da4829e2"
      unitRef="shares">4600000</us-gaap:StockRepurchasedAndRetiredDuringPeriodShares>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodValue
      contextRef="i6271ffbf65cf467783eea9a8f4a54fb0_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjgtNS0xLTEtMA_0ccaa74a-cdec-4100-abbb-23b0492a79fd"
      unitRef="usd">1069000000</us-gaap:StockRepurchasedAndRetiredDuringPeriodValue>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodValue
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMjgtOS0xLTEtMA_f9c6ed4a-c87b-4393-b449-0f4cfcdc5fc6"
      unitRef="usd">1069000000</us-gaap:StockRepurchasedAndRetiredDuringPeriodValue>
    <us-gaap:CommonStockSharesOutstanding
      contextRef="i326b605172394be1a3158d27be23c5d3_I20210930"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMzAtMS0xLTEtMA_5530e033-7381-4fe8-a56d-37caec0e33bc"
      unitRef="shares">565000000.0</us-gaap:CommonStockSharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="id005bde0830f48398b26dea00beb0a27_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMzAtMy0xLTEtMA_fa66c90a-bfbd-4d19-87cf-343dcfe422a8"
      unitRef="usd">31989000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i3deeda31d541496fbfdcf359358e2e31_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMzAtNS0xLTEtMA_9a02a6d1-84f4-48a9-a8e4-471bdcdc4f1a"
      unitRef="usd">-22964000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="ic860f31327384ad08f5dbf6d59cdb763_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMzAtNy0xLTEtMA_6296c165-604d-4222-92a7-307dc541ee11"
      unitRef="usd">-808000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOjA0YWU4MmQ3N2IyMDRiYmY4NTFhMGQ1NDk0NGQzYTNiL3RhYmxlcmFuZ2U6MDRhZTgyZDc3YjIwNGJiZjg1MWEwZDU0OTQ0ZDNhM2JfMzAtOS0xLTEtMA_04575772-1f0b-4eea-b091-bf2f1f1ed313"
      unitRef="usd">8217000000</us-gaap:StockholdersEquity>
    <us-gaap:CommonStockSharesOutstanding
      contextRef="i9383ea8be6554a1fab020c889f98f560_I20191231"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMS0xLTEtMS0w_b0377c35-91ed-439a-a8f8-0efc7863e12e"
      unitRef="shares">591400000</us-gaap:CommonStockSharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="i9fa8d9073cbb4a5e8bd57d0450a06268_I20191231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMS0zLTEtMS0w_d0fc4e3f-8ef7-4455-a0b4-18bf233f12b9"
      unitRef="usd">31531000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i27c34688721e4c3eab67f6dfab55e1ea_I20191231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMS01LTEtMS0w_1de432bd-23e0-4747-9e52-92c3e9b8063c"
      unitRef="usd">-21330000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i3b1542b7bb8c42d092dd7b4a59e1c916_I20191231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMS03LTEtMS0w_b8e8791d-2bf2-4cf3-8d3c-dc183818bbfe"
      unitRef="usd">-528000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="id63942c02328404c8dac62b9840ef120_I20191231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMS05LTEtMS0w_c7acded9-e5b4-4903-aa38-aaed7c266e6a"
      unitRef="usd">9673000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="iac88abda0f2a4f44ab3e6e7248813631_I20191231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMi01LTEtMS0w_822dd258-a0e8-4507-9d72-1741a8a2e9f2"
      unitRef="usd">-2000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i093220b291f2482d91c2fbc2c9ffff00_I20191231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMi05LTEtMS0w_0e782a23-b519-49e5-b5ed-0a2592ec897f"
      unitRef="usd">-2000000</us-gaap:StockholdersEquity>
    <us-gaap:NetIncomeLoss
      contextRef="ic041513a75144cdd9d651b4d92760425_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMy01LTEtMS0w_7c494a36-9c51-440b-b893-eedde139868e"
      unitRef="usd">1825000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMy05LTEtMS0w_0be10005-802b-496c-8858-9c317c052cfc"
      unitRef="usd">1825000000</us-gaap:NetIncomeLoss>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTax
      contextRef="i1203a51d54b041baa767dda74da28ae7_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNC03LTEtMS0w_e27043e2-8d19-4266-8fc3-298daaec5c02"
      unitRef="usd">-134000000</us-gaap:OtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTax
      contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNC05LTEtMS0w_b4569ea1-bb7c-45d3-ba28-bc7f59c30b57"
      unitRef="usd">-134000000</us-gaap:OtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:CommonStockDividendsPerShareDeclared
      contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNS0wLTEtMS0wL3RleHRyZWdpb246OWM4ZWQ3OGIxNzNmNGJmZmI1MzQ2M2M4Zjk2MGJkMmNfNDE_d3764b02-c491-4a7a-b9a0-5ca8220f5016"
      unitRef="usdPerShare">1.60</us-gaap:CommonStockDividendsPerShareDeclared>
    <us-gaap:DividendsCommonStockCash
      contextRef="ic041513a75144cdd9d651b4d92760425_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNS01LTEtMS0w_80441d65-49e0-43bf-bd0a-cbbe69c7251d"
      unitRef="usd">938000000</us-gaap:DividendsCommonStockCash>
    <us-gaap:DividendsCommonStockCash
      contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNS05LTEtMS0w_237fc524-3e48-4973-9ba5-99e30bc84e34"
      unitRef="usd">938000000</us-gaap:DividendsCommonStockCash>
    <us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation
      contextRef="i2ce25f9016044114882e77dd2ae1c3db_D20200101-20200331"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNi0xLTEtMS0w_b15d7e21-2439-4701-9062-d9887da8efe9"
      unitRef="shares">900000</us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation>
    <us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation
      contextRef="i8d2a343e4cc5455eb9ba7ef31b5fc432_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNi0zLTEtMS0w_d095a377-d4c9-4129-9154-2de80cdba10c"
      unitRef="usd">10000000</us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation>
    <us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation
      contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNi05LTEtMS0w_0c918ecd-1272-4d56-b0f6-e5708fc601dd"
      unitRef="usd">10000000</us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="i8d2a343e4cc5455eb9ba7ef31b5fc432_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNy0zLTEtMS0w_89fc0005-3248-472a-bbc0-856de21115ae"
      unitRef="usd">52000000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfNy05LTEtMS0w_c111f44d-e959-415f-9684-e8a7d73b6fae"
      unitRef="usd">52000000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet
      contextRef="i8d2a343e4cc5455eb9ba7ef31b5fc432_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfOC0zLTEtMS0w_2c71b982-9c64-430a-b855-6d207b8f20ff"
      unitRef="usd">-68000000</us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet>
    <us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet
      contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfOC05LTEtMS0w_535a63e9-5634-4461-b5cc-b22f4ad0b9cf"
      unitRef="usd">-68000000</us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodShares
      contextRef="i2ce25f9016044114882e77dd2ae1c3db_D20200101-20200331"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfOS0xLTEtMS0w_c920933d-6842-4b9b-9a69-5161cfadb3f0"
      unitRef="shares">4300000</us-gaap:StockRepurchasedAndRetiredDuringPeriodShares>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodValue
      contextRef="ic041513a75144cdd9d651b4d92760425_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfOS01LTEtMS0w_48153983-eaae-4a98-8200-d3064f0beee6"
      unitRef="usd">933000000</us-gaap:StockRepurchasedAndRetiredDuringPeriodValue>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodValue
      contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfOS05LTEtMS0w_e3b4454a-b875-475d-86e5-da5b31cc8e17"
      unitRef="usd">933000000</us-gaap:StockRepurchasedAndRetiredDuringPeriodValue>
    <us-gaap:CommonStockSharesOutstanding
      contextRef="ibc414a46e88b4e40a79c00cb9bfd0717_I20200331"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTAtMS0xLTEtMA_629821a8-4c23-413a-a5bc-0eb2a76af587"
      unitRef="shares">588000000.0</us-gaap:CommonStockSharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="i8ff21ac5e59f4e1c9aaf71c8a6427a9b_I20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTAtMy0xLTEtMA_f57dfd3c-ae9b-4fa7-b29f-b91fb8470421"
      unitRef="usd">31525000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="ieb7177b91ced43c4bb32d3c71fc60664_I20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTAtNS0xLTEtMA_2fc859c1-85a0-416d-b147-985a7cdabb7a"
      unitRef="usd">-21378000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i9ab337ca3f8b490685a1514d21ef0795_I20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTAtNy0xLTEtMA_c5661163-3c68-444d-b8df-25670f9e45e8"
      unitRef="usd">-662000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i97aafa8c1ca149ab98952ad235869d3d_I20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTAtOS0xLTEtMA_512407ee-7a94-44ae-9af5-029e212217de"
      unitRef="usd">9485000000</us-gaap:StockholdersEquity>
    <us-gaap:NetIncomeLoss
      contextRef="iad1c7381eead460f9f20a42237bbc0ab_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTItNS0xLTEtMA_0467a147-f5de-4fa7-803b-bf41d9b65385"
      unitRef="usd">1803000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTItOS0xLTEtMA_249bac9c-bd56-4a41-a869-6287f2fe694b"
      unitRef="usd">1803000000</us-gaap:NetIncomeLoss>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTax
      contextRef="ia9f6aa7d77f443dfb9ccbbf4060d7af0_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTMtNy0xLTEtMA_c9447911-29e1-49ec-8f93-109923bb1799"
      unitRef="usd">-121000000</us-gaap:OtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTax
      contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTMtOS0xLTEtMA_39447008-de74-4d43-8730-edfb4f33da14"
      unitRef="usd">-121000000</us-gaap:OtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation
      contextRef="if8027892520a4ca5bd94f4c5cfcec8a0_D20200401-20200630"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTUtMS0xLTEtMA_ed32e901-735f-41af-9ed3-3b3f7a259265"
      unitRef="shares">1000000.0</us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation>
    <us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation
      contextRef="i7896d230ca994182af0336d7fc0f319c_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTUtMy0xLTEtMA_aaa7407c-68da-49d9-9cc1-4a9c62fc7606"
      unitRef="usd">65000000</us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation>
    <us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation
      contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTUtOS0xLTEtMA_b959a4ac-b113-43d4-b7a4-480cbc3b7780"
      unitRef="usd">65000000</us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="i7896d230ca994182af0336d7fc0f319c_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTYtMy0xLTEtMA_c8531d37-e580-4834-9e14-bfc589673e6f"
      unitRef="usd">101000000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTYtOS0xLTEtMA_4b066a1e-1817-4938-9e3b-1647fd6e49d6"
      unitRef="usd">101000000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet
      contextRef="i7896d230ca994182af0336d7fc0f319c_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTctMy0xLTEtMA_d08b5f4a-3e20-4875-b532-8549b770e12f"
      unitRef="usd">-81000000</us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet>
    <us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet
      contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTctOS0xLTEtMA_9a1212d6-0914-41f4-9ccf-835b56dadbd9"
      unitRef="usd">-81000000</us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodShares
      contextRef="if8027892520a4ca5bd94f4c5cfcec8a0_D20200401-20200630"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTgtMS0xLTEtMA_da457d7e-51fc-4d51-ad07-10e9a505d2fa"
      unitRef="shares">2600000</us-gaap:StockRepurchasedAndRetiredDuringPeriodShares>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodValue
      contextRef="iad1c7381eead460f9f20a42237bbc0ab_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTgtNS0xLTEtMA_08d23eee-694d-4394-adec-cb53e20b4bb4"
      unitRef="usd">591000000</us-gaap:StockRepurchasedAndRetiredDuringPeriodValue>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodValue
      contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTgtOS0xLTEtMA_eed53ef5-ceb2-4276-9003-a6920d2d4da9"
      unitRef="usd">591000000</us-gaap:StockRepurchasedAndRetiredDuringPeriodValue>
    <us-gaap:StockholdersEquityOther
      contextRef="iad1c7381eead460f9f20a42237bbc0ab_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTktNS0xLTEtMA_59480b55-6a89-429f-9e05-fce081b82ab8"
      unitRef="usd">-2000000</us-gaap:StockholdersEquityOther>
    <us-gaap:StockholdersEquityOther
      contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMTktOS0xLTEtMA_831f4f28-5942-438f-8b75-a3358b2e3374"
      unitRef="usd">-2000000</us-gaap:StockholdersEquityOther>
    <us-gaap:CommonStockSharesOutstanding
      contextRef="ia393209bc348462397965e66e877a084_I20200630"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjAtMS0xLTEtMA_b1036765-4f79-4100-bb0e-d9bf08b0d7e3"
      unitRef="shares">586400000</us-gaap:CommonStockSharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="i8a3527abf717402c896edf9e49b60c2b_I20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjAtMy0xLTEtMA_87e6e9f8-fac8-4a29-95cb-616fbbeffe18"
      unitRef="usd">31610000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i9c61b9be9ad3458088feb12ba9d330d6_I20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjAtNS0xLTEtMA_0ac1b8cf-40e7-4503-8090-bdbfca88d0dc"
      unitRef="usd">-20168000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="ib5bc8ed5ffb54e45bdec39111af0f8d5_I20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjAtNy0xLTEtMA_6841c96b-ccd0-4ef2-9717-6c5de67879cd"
      unitRef="usd">-783000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i0d016fa4aa4b4b0b8d61f8f03d2b1ad9_I20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjAtOS0xLTEtMA_d2a39fea-3c7b-467f-b03e-5341fc3bfe21"
      unitRef="usd">10659000000</us-gaap:StockholdersEquity>
    <us-gaap:NetIncomeLoss
      contextRef="i2fdcbf2c5023490a8467f390d0945384_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjItNS0xLTEtMA_68adddae-5206-448a-97b5-448461bf2714"
      unitRef="usd">2021000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjItOS0xLTEtMA_22d1face-27a8-4f93-bbb9-3b4f54e9d62a"
      unitRef="usd">2021000000</us-gaap:NetIncomeLoss>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTax
      contextRef="ia0027870c8424e858af8516bb7a32d5b_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjMtNy0xLTEtMA_0538b09e-e3b1-479c-929e-7f2a62399cb1"
      unitRef="usd">-120000000</us-gaap:OtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:OtherComprehensiveIncomeLossNetOfTax
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjMtOS0xLTEtMA_484659b9-f289-4be3-bf01-1e037e109137"
      unitRef="usd">-120000000</us-gaap:OtherComprehensiveIncomeLossNetOfTax>
    <us-gaap:CommonStockDividendsPerShareDeclared
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjQtMC0xLTEtMC90ZXh0cmVnaW9uOjBlMDYzYWVmNzhiNTQ1ZWE4MTIwZmQ5NjA4MjJkNWJlXzQw_68398fa7-acb0-45e8-81e6-73c70a844ded"
      unitRef="usdPerShare">1.60</us-gaap:CommonStockDividendsPerShareDeclared>
    <us-gaap:DividendsCommonStockCash
      contextRef="i2fdcbf2c5023490a8467f390d0945384_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjQtNS0xLTEtMA_4a672290-c819-41e1-bdf5-cfbf6037d937"
      unitRef="usd">952000000</us-gaap:DividendsCommonStockCash>
    <us-gaap:DividendsCommonStockCash
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjQtOS0xLTEtMA_f3654aa1-528b-4cfc-884c-f9541aba52d2"
      unitRef="usd">952000000</us-gaap:DividendsCommonStockCash>
    <us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation
      contextRef="ia750b0fd2e8d494f82d6c68132072625_D20200701-20200930"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjUtMS0xLTEtMA_ea43bf4e-f1ff-4923-814f-9d92a7a98300"
      unitRef="shares">100000</us-gaap:StockIssuedDuringPeriodSharesShareBasedCompensation>
    <us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation
      contextRef="if9b3a6e30225464792dc4e6abbd3a015_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjUtMy0xLTEtMA_9150c62e-2ced-48f8-ab85-9b5d081844cf"
      unitRef="usd">5000000</us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation>
    <us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjUtOS0xLTEtMA_b6a26a1a-ca32-4d23-a49b-01da11b5d5e2"
      unitRef="usd">5000000</us-gaap:StockIssuedDuringPeriodValueShareBasedCompensation>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="if9b3a6e30225464792dc4e6abbd3a015_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjYtMy0xLTEtMA_986b0d4f-600c-4bc0-b79d-09457d0ca10e"
      unitRef="usd">109000000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjYtOS0xLTEtMA_bf963ad2-8e1f-4080-95ea-f19a52a732c0"
      unitRef="usd">109000000</us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue>
    <us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet
      contextRef="if9b3a6e30225464792dc4e6abbd3a015_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjctMy0xLTEtMA_c63f6ecc-676f-4f6e-b30c-2daa76b07e77"
      unitRef="usd">-11000000</us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet>
    <us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjctOS0xLTEtMA_77f1226c-e88a-49ef-a8e2-98c08c8db405"
      unitRef="usd">-11000000</us-gaap:AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodShares
      contextRef="ia750b0fd2e8d494f82d6c68132072625_D20200701-20200930"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjgtMS0xLTEtMA_197bf668-0d15-4e57-a0df-66aad163a546"
      unitRef="shares">3000000.0</us-gaap:StockRepurchasedAndRetiredDuringPeriodShares>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodValue
      contextRef="i2fdcbf2c5023490a8467f390d0945384_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjgtNS0xLTEtMA_ccc9f54c-bc4f-444a-afc1-33e5a9961261"
      unitRef="usd">752000000</us-gaap:StockRepurchasedAndRetiredDuringPeriodValue>
    <us-gaap:StockRepurchasedAndRetiredDuringPeriodValue
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjgtOS0xLTEtMA_431ed549-965d-4b88-a7c2-fb35368bc4bf"
      unitRef="usd">752000000</us-gaap:StockRepurchasedAndRetiredDuringPeriodValue>
    <us-gaap:CommonStockSharesOutstanding
      contextRef="id0c6f5eb460b4312bb606fc4ad30a816_I20200930"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjktMS0xLTEtMA_d2502aac-0952-49e0-947a-0aa57b19c214"
      unitRef="shares">583500000</us-gaap:CommonStockSharesOutstanding>
    <us-gaap:StockholdersEquity
      contextRef="i7ca21439af704771b81a4e07e28ca15c_I20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjktMy0xLTEtMA_8786ccf3-afa9-4c8a-85b0-1ee1845c5edf"
      unitRef="usd">31713000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i18ba9dc7e2ca40f5b5ccd5e684f54c7a_I20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjktNS0xLTEtMA_90ba0c75-39a5-444b-9c37-77a34d5cd1e0"
      unitRef="usd">-19851000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i5368a3d307444f2c801d6b1d0963ec11_I20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjktNy0xLTEtMA_df91f94c-153b-478b-927f-e548efd7427b"
      unitRef="usd">-903000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i1a997bb47af74377a26fb3c2164ec5a6_I20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yNS9mcmFnOjEwYWE2MTI0MThhZjQ2MDQ4ZDI1N2M4ZGU5ZmRlODQ3L3RhYmxlOmFjMjIwZjQ0YTczNDQ1NzJiNDU5YmY0ODIzZGFkMzU0L3RhYmxlcmFuZ2U6YWMyMjBmNDRhNzM0NDU3MmI0NTliZjQ4MjNkYWQzNTRfMjktOS0xLTEtMA_e258371b-8609-4625-a9a8-b4d72a0e07d0"
      unitRef="usd">10959000000</us-gaap:StockholdersEquity>
    <us-gaap:NetIncomeLoss
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMy0xLTEtMS0w_528eb014-e4f7-44a3-a2b6-47d16664455f"
      unitRef="usd">3994000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMy0zLTEtMS0w_d796a6ee-fff0-480a-b7f2-3f1a701546f0"
      unitRef="usd">5649000000</us-gaap:NetIncomeLoss>
    <us-gaap:DepreciationDepletionAndAmortization
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNC0xLTEtMS0w_29729e64-6408-40f9-9ae0-97510ef23552"
      unitRef="usd">2546000000</us-gaap:DepreciationDepletionAndAmortization>
    <us-gaap:DepreciationDepletionAndAmortization
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNC0zLTEtMS0w_057a30c0-cbbd-4a6a-8640-3a1f1a8038b8"
      unitRef="usd">2728000000</us-gaap:DepreciationDepletionAndAmortization>
    <us-gaap:DeferredIncomeTaxesAndTaxCredits
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNS0xLTEtMS0w_08c42bad-737f-40bc-8967-c76be62120c7"
      unitRef="usd">-264000000</us-gaap:DeferredIncomeTaxesAndTaxCredits>
    <us-gaap:DeferredIncomeTaxesAndTaxCredits
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNS0zLTEtMS0w_6387e396-242f-4fcb-8969-2e7456a8b8bd"
      unitRef="usd">-339000000</us-gaap:DeferredIncomeTaxesAndTaxCredits>
    <us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNi0xLTEtMS0w_ed974ff0-7cf3-455f-ae2e-8423b794fe25"
      unitRef="usd">1505000000</us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff>
    <us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNi0zLTEtMS0w_be3adaaa-55cf-4277-b5f6-72d5b68cd938"
      unitRef="usd">0</us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff>
    <us-gaap:OtherNoncashIncomeExpense
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNy0xLTEtMS0w_ac4c60e0-be85-4dae-bad5-e8325de7851e"
      unitRef="usd">-187000000</us-gaap:OtherNoncashIncomeExpense>
    <us-gaap:OtherNoncashIncomeExpense
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfNy0zLTEtMS0w_5585512e-317b-41ff-bee7-fedb5665250a"
      unitRef="usd">-270000000</us-gaap:OtherNoncashIncomeExpense>
    <us-gaap:IncreaseDecreaseInAccountsReceivable
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfOS0xLTEtMS0w_ca57aa33-10cb-4135-88ed-4eb82bea043c"
      unitRef="usd">269000000</us-gaap:IncreaseDecreaseInAccountsReceivable>
    <us-gaap:IncreaseDecreaseInAccountsReceivable
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfOS0zLTEtMS0w_c6ca3694-b604-4d05-ba53-c9bad6269a55"
      unitRef="usd">31000000</us-gaap:IncreaseDecreaseInAccountsReceivable>
    <us-gaap:IncreaseDecreaseInInventories
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTAtMS0xLTEtMA_9faec344-05a6-4452-b7f6-78a3ecd42190"
      unitRef="usd">215000000</us-gaap:IncreaseDecreaseInInventories>
    <us-gaap:IncreaseDecreaseInInventories
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTAtMy0xLTEtMA_75da856b-dafb-407c-86f7-6ce095150444"
      unitRef="usd">316000000</us-gaap:IncreaseDecreaseInInventories>
    <us-gaap:IncreaseDecreaseInOtherOperatingAssets
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTEtMS0xLTEtMA_4b868ffc-6b7d-47ab-9ff7-922b9eb5191c"
      unitRef="usd">373000000</us-gaap:IncreaseDecreaseInOtherOperatingAssets>
    <us-gaap:IncreaseDecreaseInOtherOperatingAssets
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTEtMy0xLTEtMA_2f4193e6-bd3b-4bd5-a3bf-c331325c53f6"
      unitRef="usd">-64000000</us-gaap:IncreaseDecreaseInOtherOperatingAssets>
    <us-gaap:IncreaseDecreaseInAccountsPayable
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTItMS0xLTEtMA_325aa58d-af87-46c4-9161-bb63a2f6c3c9"
      unitRef="usd">-260000000</us-gaap:IncreaseDecreaseInAccountsPayable>
    <us-gaap:IncreaseDecreaseInAccountsPayable
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTItMy0xLTEtMA_729c4f8e-c96f-44f5-be2a-314a76c910b0"
      unitRef="usd">-202000000</us-gaap:IncreaseDecreaseInAccountsPayable>
    <us-gaap:IncreaseDecreaseInAccruedIncomeTaxesPayable
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTMtMS0xLTEtMA_2b9e5d76-8901-45cb-901b-10214146fdf4"
      unitRef="usd">-719000000</us-gaap:IncreaseDecreaseInAccruedIncomeTaxesPayable>
    <us-gaap:IncreaseDecreaseInAccruedIncomeTaxesPayable
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTMtMy0xLTEtMA_15f2fe9d-88b1-48d2-84ef-287a340d6a96"
      unitRef="usd">-301000000</us-gaap:IncreaseDecreaseInAccruedIncomeTaxesPayable>
    <amgn:IncreaseDecreaseInNoncurrentTaxLiability
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTQtMS0xLTEtMA_4af9b816-b11e-4af1-ad64-a64dd7877722"
      unitRef="usd">102000000</amgn:IncreaseDecreaseInNoncurrentTaxLiability>
    <amgn:IncreaseDecreaseInNoncurrentTaxLiability
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTQtMy0xLTEtMA_44d5654a-5289-4524-8a08-e90435749aba"
      unitRef="usd">110000000</amgn:IncreaseDecreaseInNoncurrentTaxLiability>
    <us-gaap:IncreaseDecreaseInOtherOperatingLiabilities
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTUtMS0xLTEtMA_255d1abf-bb07-4c42-8deb-7adfd32e2351"
      unitRef="usd">219000000</us-gaap:IncreaseDecreaseInOtherOperatingLiabilities>
    <us-gaap:IncreaseDecreaseInOtherOperatingLiabilities
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTUtMy0xLTEtMA_b329c2a1-4523-4be9-9632-89a82f9c74d9"
      unitRef="usd">712000000</us-gaap:IncreaseDecreaseInOtherOperatingLiabilities>
    <us-gaap:NetCashProvidedByUsedInOperatingActivities
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTYtMS0xLTEtMA_153068b0-4ef5-44a3-b8cd-9025d1affdf8"
      unitRef="usd">6453000000</us-gaap:NetCashProvidedByUsedInOperatingActivities>
    <us-gaap:NetCashProvidedByUsedInOperatingActivities
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTYtMy0xLTEtMA_cf918b75-0012-4166-b982-b9d05eede1d6"
      unitRef="usd">8344000000</us-gaap:NetCashProvidedByUsedInOperatingActivities>
    <us-gaap:PaymentsToAcquireBusinessesNetOfCashAcquired
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTgtMS0xLTEtMA_608a82e2-f5a3-466d-80ef-e88ad334a857"
      unitRef="usd">1639000000</us-gaap:PaymentsToAcquireBusinessesNetOfCashAcquired>
    <us-gaap:PaymentsToAcquireBusinessesNetOfCashAcquired
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTgtMy0xLTEtMA_8c7ff196-f509-494d-ac0f-f0c2b489300a"
      unitRef="usd">0</us-gaap:PaymentsToAcquireBusinessesNetOfCashAcquired>
    <us-gaap:PaymentsToAcquireMarketableSecurities
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTktMS0xLTEtMA_6d2111b3-57fb-44dd-8eb3-322b34cc5dc3"
      unitRef="usd">8901000000</us-gaap:PaymentsToAcquireMarketableSecurities>
    <us-gaap:PaymentsToAcquireMarketableSecurities
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMTktMy0xLTEtMA_79a623c2-cded-4ff4-ad91-a309a3143cc8"
      unitRef="usd">5329000000</us-gaap:PaymentsToAcquireMarketableSecurities>
    <us-gaap:ProceedsFromSaleOfAvailableForSaleSecuritiesDebt
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjAtMS0xLTEtMA_95774a50-54f1-4617-bfda-768ec2873c5d"
      unitRef="usd">4403000000</us-gaap:ProceedsFromSaleOfAvailableForSaleSecuritiesDebt>
    <us-gaap:ProceedsFromSaleOfAvailableForSaleSecuritiesDebt
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjAtMy0xLTEtMA_7dd9ea5a-6a8e-4788-a1d0-52cb7c75af8d"
      unitRef="usd">2597000000</us-gaap:ProceedsFromSaleOfAvailableForSaleSecuritiesDebt>
    <us-gaap:ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjEtMS0xLTEtMA_222e56a2-bcc3-4b62-967e-2214e9679168"
      unitRef="usd">7927000000</us-gaap:ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities>
    <us-gaap:ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjEtMy0xLTEtMA_f200c10d-70e1-4d74-a05c-0857b61596a8"
      unitRef="usd">2338000000</us-gaap:ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities>
    <us-gaap:PaymentsToAcquirePropertyPlantAndEquipment
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjMtMS0xLTEtMA_49fd8c22-6abb-4b96-902b-8306b7974400"
      unitRef="usd">593000000</us-gaap:PaymentsToAcquirePropertyPlantAndEquipment>
    <us-gaap:PaymentsToAcquirePropertyPlantAndEquipment
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjMtMy0xLTEtMA_bc467f87-215d-48b5-a3cb-5c0579807515"
      unitRef="usd">435000000</us-gaap:PaymentsToAcquirePropertyPlantAndEquipment>
    <us-gaap:PaymentsToAcquireEquityMethodInvestments
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjQtMS0xLTEtMA_f22be5dd-abaa-4618-a789-e9dce6d4482b"
      unitRef="usd">154000000</us-gaap:PaymentsToAcquireEquityMethodInvestments>
    <us-gaap:PaymentsToAcquireEquityMethodInvestments
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjQtMy0xLTEtMA_7c5dc45b-baea-4741-8ae9-6e93ebb04bca"
      unitRef="usd">3154000000</us-gaap:PaymentsToAcquireEquityMethodInvestments>
    <us-gaap:PaymentsForProceedsFromOtherInvestingActivities
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjUtMS0xLTEtMA_e696c439-cc1e-480d-b8c4-29b756352bbc"
      unitRef="usd">80000000</us-gaap:PaymentsForProceedsFromOtherInvestingActivities>
    <us-gaap:PaymentsForProceedsFromOtherInvestingActivities
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjUtMy0xLTEtMA_f6645411-86a0-43da-adc5-f3431834f416"
      unitRef="usd">34000000</us-gaap:PaymentsForProceedsFromOtherInvestingActivities>
    <us-gaap:NetCashProvidedByUsedInInvestingActivities
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjYtMS0xLTEtMA_c5d829bd-aa33-459d-a88c-7cdc02d1869e"
      unitRef="usd">963000000</us-gaap:NetCashProvidedByUsedInInvestingActivities>
    <us-gaap:NetCashProvidedByUsedInInvestingActivities
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjYtMy0xLTEtMA_ca5ef050-c636-4b98-92e9-3220700e93f8"
      unitRef="usd">-4017000000</us-gaap:NetCashProvidedByUsedInInvestingActivities>
    <us-gaap:ProceedsFromIssuanceOfLongTermDebt
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjgtMS0xLTEtMA_e0abfc46-cca4-4a1a-860a-60451a0c53cf"
      unitRef="usd">4946000000</us-gaap:ProceedsFromIssuanceOfLongTermDebt>
    <us-gaap:ProceedsFromIssuanceOfLongTermDebt
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjgtMy0xLTEtMA_f3bfb1ec-5608-4d17-8409-791c56bb27e3"
      unitRef="usd">8914000000</us-gaap:ProceedsFromIssuanceOfLongTermDebt>
    <us-gaap:RepaymentsOfLongTermDebt
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjktMS0xLTEtMA_6ddd4561-a898-416c-9a88-1a9fe130d8ad"
      unitRef="usd">0</us-gaap:RepaymentsOfLongTermDebt>
    <us-gaap:RepaymentsOfLongTermDebt
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMjktMy0xLTEtMA_9736462c-0e13-4571-8b92-28dbe57771ba"
      unitRef="usd">5000000000</us-gaap:RepaymentsOfLongTermDebt>
    <us-gaap:PaymentsForRepurchaseOfCommonStock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzEtMS0xLTEtMA_12fe3aa9-8f6a-40af-a527-eae28be3f1e6"
      unitRef="usd">3532000000</us-gaap:PaymentsForRepurchaseOfCommonStock>
    <us-gaap:PaymentsForRepurchaseOfCommonStock
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzEtMy0xLTEtMA_4076ff53-e1cf-49b6-bf06-a163958054cd"
      unitRef="usd">2281000000</us-gaap:PaymentsForRepurchaseOfCommonStock>
    <us-gaap:PaymentsOfDividendsCommonStock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzItMS0xLTEtMA_ac273f95-d044-49f4-b162-a73465522ac4"
      unitRef="usd">3023000000</us-gaap:PaymentsOfDividendsCommonStock>
    <us-gaap:PaymentsOfDividendsCommonStock
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzItMy0xLTEtMA_dcb04943-28b1-4278-bd43-d5e44e02e9b9"
      unitRef="usd">2823000000</us-gaap:PaymentsOfDividendsCommonStock>
    <us-gaap:ProceedsFromPaymentsForOtherFinancingActivities
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzQtMS0xLTEtMA_6e9472a9-cff6-4932-821e-a9c6132e8ebf"
      unitRef="usd">-104000000</us-gaap:ProceedsFromPaymentsForOtherFinancingActivities>
    <us-gaap:ProceedsFromPaymentsForOtherFinancingActivities
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzQtMy0xLTEtMA_c74d8258-1663-4659-a6a3-97b85e98ef38"
      unitRef="usd">-87000000</us-gaap:ProceedsFromPaymentsForOtherFinancingActivities>
    <us-gaap:NetCashProvidedByUsedInFinancingActivities
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzUtMS0xLTEtMA_52635159-7af3-4651-9122-7a7dc54b238c"
      unitRef="usd">-1713000000</us-gaap:NetCashProvidedByUsedInFinancingActivities>
    <us-gaap:NetCashProvidedByUsedInFinancingActivities
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzUtMy0xLTEtMA_b6e5a5b1-b336-40f4-99e8-07551d8fe2c8"
      unitRef="usd">-1277000000</us-gaap:NetCashProvidedByUsedInFinancingActivities>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzYtMS0xLTEtMA_a18dfc5e-b071-4233-a22d-cd68e4d08ca6"
      unitRef="usd">5703000000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzYtMy0xLTEtMA_0f7937b1-6457-49bb-8a7a-1bffbbdb1560"
      unitRef="usd">3050000000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzctMS0xLTEtMA_c3f47fcb-a505-416e-a45e-77e805bebd2e"
      unitRef="usd">6266000000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
      contextRef="id63942c02328404c8dac62b9840ef120_I20191231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzctMy0xLTEtMA_4295d9f0-4d4f-4ec7-b68e-c4624b60f3e1"
      unitRef="usd">6037000000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzgtMS0xLTEtMA_e2e130a1-d72f-4f54-840e-2ec9bed9a6ed"
      unitRef="usd">11969000000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
      contextRef="i1a997bb47af74377a26fb3c2164ec5a6_I20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8yOC9mcmFnOjJkMGE0NjAxZTY3NTQyZGM5MDBhODBkN2JlNTViOWEyL3RhYmxlOmRlNjc2YjI3NmU5MjRiNmNiMzg3NjFjZWU4NDBhZmE5L3RhYmxlcmFuZ2U6ZGU2NzZiMjc2ZTkyNGI2Y2IzODc2MWNlZTg0MGFmYTlfMzgtMy0xLTEtMA_336f4261-f078-4b67-a3b3-3ad5d4f246f2"
      unitRef="usd">9087000000</us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents>
    <us-gaap:SignificantAccountingPoliciesTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMzI3Mw_0a4fb2e0-9b55-4b26-abe6-0031dc1cd5e0">Summary of significant accounting policies&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Business&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Amgen Inc. (including its subsidiaries, referred to as &#x201c;Amgen,&#x201d; &#x201c;the Company,&#x201d; &#x201c;we,&#x201d; &#x201c;our&#x201d; or &#x201c;us&#x201d;) is a global biotechnology pioneer that discovers, develops, manufactures and delivers innovative human therapeutics.&#160;We operate in one business segment: human therapeutics.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Basis of presentation&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The financial information for the three and nine months ended September 30, 2021 and 2020, is unaudited but includes all adjustments (consisting of only normal, recurring adjustments unless otherwise indicated), which Amgen considers necessary for a fair presentation of its condensed consolidated results of operations for those periods. Interim results are not necessarily indicative of results for the full fiscal year.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The condensed consolidated financial statements should be read in conjunction with our consolidated financial statements and the notes thereto contained in our Annual Report on Form 10-K for the year ended December 31, 2020, and with our condensed consolidated financial statements and the notes thereto contained in our Quarterly Reports on Form 10-Q for the periods ended March 31, 2021 and June 30, 2021.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Principles of consolidation&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The condensed consolidated financial statements include the accounts of Amgen as well as its majority-owned subsidiaries. We do not have any significant interests in any&lt;/span&gt;&lt;span style="color:#ff0000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;variable interest entities. All material intercompany transactions and balances have been eliminated in consolidation.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Use of estimates&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The preparation of condensed consolidated financial statements in conformity with U.S. generally accepted accounting principles (GAAP) requires management to make estimates and assumptions that affect the amounts reported in the condensed consolidated financial statements and accompanying notes. Actual results may differ from those estimates.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Property, plant and equipment, net&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Property, plant and equipment is recorded at historical cost, net of accumulated depreciation and amortization of $9.2&#160;billion and $9.0 billion as of September 30, 2021 and December 31, 2020, respectively.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Recent accounting pronouncements&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;In March 2020, the Financial Accounting Standards Board (FASB) issued a new accounting standard to ease the financial reporting burdens caused by the expected market transition from the London Interbank Offered Rate (LIBOR) and other interbank offered rates to alternative reference rates, commonly referred to as reference rate reform. The new standard provides temporary optional expedients and exceptions to current GAAP guidance on contract modifications and hedge accounting. Specifically, a modification to transition to an alternative reference rate is treated as an event that does not require contract remeasurement or reassessment of a previous accounting treatment. Moreover, for all types of hedging relationships, an entity is permitted to change the reference rate without having to dedesignate the hedging relationship. The standard is generally effective for all contract modifications made and hedging relationships evaluated through December 31, 2022. In January 2021, the FASB issued a new accounting standard to expand on the scope of the original March 2020 standard to include derivative instruments on discounting transactions. We are currently evaluating the impacts that the two standards will have on our condensed consolidated financial statements.&lt;/span&gt;&lt;/div&gt;</us-gaap:SignificantAccountingPoliciesTextBlock>
    <amgn:NatureOfOperationsPolicyTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMzMwNw_6e1570de-d9e5-48ab-94e6-e25ee2cdc46f">&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Business&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Amgen Inc. (including its subsidiaries, referred to as &#x201c;Amgen,&#x201d; &#x201c;the Company,&#x201d; &#x201c;we,&#x201d; &#x201c;our&#x201d; or &#x201c;us&#x201d;) is a global biotechnology pioneer that discovers, develops, manufactures and delivers innovative human therapeutics.&#160;We operate in one business segment: human therapeutics.&lt;/span&gt;&lt;/div&gt;</amgn:NatureOfOperationsPolicyTextBlock>
    <us-gaap:NumberOfOperatingSegments
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMjUz_efda5004-ea88-467f-a02d-4c63c386cc0c"
      unitRef="segment">1</us-gaap:NumberOfOperatingSegments>
    <amgn:BasisOfPresentationPolicyTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMzI2Ng_c836ee22-052a-459e-980b-a71ccdc2ddea">&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Basis of presentation&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The financial information for the three and nine months ended September 30, 2021 and 2020, is unaudited but includes all adjustments (consisting of only normal, recurring adjustments unless otherwise indicated), which Amgen considers necessary for a fair presentation of its condensed consolidated results of operations for those periods. Interim results are not necessarily indicative of results for the full fiscal year.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The condensed consolidated financial statements should be read in conjunction with our consolidated financial statements and the notes thereto contained in our Annual Report on Form 10-K for the year ended December 31, 2020, and with our condensed consolidated financial statements and the notes thereto contained in our Quarterly Reports on Form 10-Q for the periods ended March 31, 2021 and June 30, 2021.&lt;/span&gt;&lt;/div&gt;</amgn:BasisOfPresentationPolicyTextBlock>
    <us-gaap:ConsolidationPolicyTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMzI0OA_cbe75e0b-38e1-439f-a541-92d4a9935dc8">&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Principles of consolidation&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The condensed consolidated financial statements include the accounts of Amgen as well as its majority-owned subsidiaries. We do not have any significant interests in any&lt;/span&gt;&lt;span style="color:#ff0000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;variable interest entities. All material intercompany transactions and balances have been eliminated in consolidation.&lt;/span&gt;&lt;/div&gt;</us-gaap:ConsolidationPolicyTextBlock>
    <us-gaap:UseOfEstimates
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMzI3Ng_5ff1e4ae-3881-4239-b692-0a7fea64f95e">&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Use of estimates&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The preparation of condensed consolidated financial statements in conformity with U.S. generally accepted accounting principles (GAAP) requires management to make estimates and assumptions that affect the amounts reported in the condensed consolidated financial statements and accompanying notes. Actual results may differ from those estimates.&lt;/span&gt;&lt;/div&gt;</us-gaap:UseOfEstimates>
    <us-gaap:PropertyPlantAndEquipmentPolicyTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMzI2NA_c42060f4-29e9-4bb4-b866-af4f35a85326">&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Property, plant and equipment, net&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Property, plant and equipment is recorded at historical cost, net of accumulated depreciation and amortization of $9.2&#160;billion and $9.0 billion as of September 30, 2021 and December 31, 2020, respectively.&lt;/span&gt;&lt;/div&gt;</us-gaap:PropertyPlantAndEquipmentPolicyTextBlock>
    <us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMTg5OA_06877cb9-5d99-41e1-ad40-d2ec966fae98"
      unitRef="usd">9200000000</us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment>
    <us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMTkwNQ_70d663f1-b9f3-478e-8c03-5b1cab971fc2"
      unitRef="usd">9000000000</us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment>
    <us-gaap:NewAccountingPronouncementsPolicyPolicyTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNC9mcmFnOjMzNmFmNDQ3YjExZTQ2NGY4NTU0ZDk4NGJkNTY2MDAyL3RleHRyZWdpb246MzM2YWY0NDdiMTFlNDY0Zjg1NTRkOTg0YmQ1NjYwMDJfMzI5Nw_806c23a9-af67-4694-8225-09e3e561cb49">&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Recent accounting pronouncements&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;In March 2020, the Financial Accounting Standards Board (FASB) issued a new accounting standard to ease the financial reporting burdens caused by the expected market transition from the London Interbank Offered Rate (LIBOR) and other interbank offered rates to alternative reference rates, commonly referred to as reference rate reform. The new standard provides temporary optional expedients and exceptions to current GAAP guidance on contract modifications and hedge accounting. Specifically, a modification to transition to an alternative reference rate is treated as an event that does not require contract remeasurement or reassessment of a previous accounting treatment. Moreover, for all types of hedging relationships, an entity is permitted to change the reference rate without having to dedesignate the hedging relationship. The standard is generally effective for all contract modifications made and hedging relationships evaluated through December 31, 2022. In January 2021, the FASB issued a new accounting standard to expand on the scope of the original March 2020 standard to include derivative instruments on discounting transactions. We are currently evaluating the impacts that the two standards will have on our condensed consolidated financial statements.&lt;/span&gt;&lt;/div&gt;</us-gaap:NewAccountingPronouncementsPolicyPolicyTextBlock>
    <us-gaap:BusinessCombinationDisclosureTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNy9mcmFnOmM1MzFiN2NmODEzZDRlNGNhZmEyMGNhMjA1MDNmNGM0L3RleHRyZWdpb246YzUzMWI3Y2Y4MTNkNGU0Y2FmYTIwY2EyMDUwM2Y0YzRfOTUy_332e78c6-385f-4e66-8731-bfad928bfa55">Acquisitions&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;On April 16, 2021, Amgen completed its acquisition of Five Prime Therapeutics, Inc. (Five Prime) for total consideration of $1.6&#160;billion, net of cash acquired. The purchase price was funded with cash on hand. This transaction was accounted for as an asset acquisition because substantially all the value of the assets acquired was concentrated in the intellectual property rights of bemarituzumab, a phase 3 trial-ready, first-in-class program for gastric cancer. Five Prime&#x2019;s operations have been included in our condensed consolidated financial statements commencing after the acquisition date.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;We allocated the consideration to acquire Five Prime to: the bemarituzumab in-process research and development (IPR&amp;amp;D) program of $1.5&#160;billion, which was expensed immediately in Acquired IPR&amp;amp;D expense in the Condensed Consolidated Statements of Income; deferred tax assets of $177&#160;million; and other net liabilities of $47&#160;million. The acquired IPR&amp;amp;D expense was not tax deductible.&lt;/span&gt;&lt;/div&gt;</us-gaap:BusinessCombinationDisclosureTextBlock>
    <us-gaap:PaymentsToAcquireBusinessesNetOfCashAcquired
      contextRef="i65976c78d95c49118311d26eb3256876_D20210416-20210416"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNy9mcmFnOmM1MzFiN2NmODEzZDRlNGNhZmEyMGNhMjA1MDNmNGM0L3RleHRyZWdpb246YzUzMWI3Y2Y4MTNkNGU0Y2FmYTIwY2EyMDUwM2Y0YzRfMTM2_93ee1082-b43b-42d4-9198-0db6a3bd7ea9"
      unitRef="usd">1600000000</us-gaap:PaymentsToAcquireBusinessesNetOfCashAcquired>
    <us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff
      contextRef="i65976c78d95c49118311d26eb3256876_D20210416-20210416"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNy9mcmFnOmM1MzFiN2NmODEzZDRlNGNhZmEyMGNhMjA1MDNmNGM0L3RleHRyZWdpb246YzUzMWI3Y2Y4MTNkNGU0Y2FmYTIwY2EyMDUwM2Y0YzRfNzI5_cc433a15-2bfc-401a-9eb9-7ecc489052b2"
      unitRef="usd">1500000000</us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff>
    <us-gaap:BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets
      contextRef="ifd83e7d77b084c5d854ddc58d39a3bcf_I20210416"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNy9mcmFnOmM1MzFiN2NmODEzZDRlNGNhZmEyMGNhMjA1MDNmNGM0L3RleHRyZWdpb246YzUzMWI3Y2Y4MTNkNGU0Y2FmYTIwY2EyMDUwM2Y0YzRfODY1_b6675964-a014-4f96-9b2c-2939eb6b5018"
      unitRef="usd">177000000</us-gaap:BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets>
    <us-gaap:BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther
      contextRef="ifd83e7d77b084c5d854ddc58d39a3bcf_I20210416"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8zNy9mcmFnOmM1MzFiN2NmODEzZDRlNGNhZmEyMGNhMjA1MDNmNGM0L3RleHRyZWdpb246YzUzMWI3Y2Y4MTNkNGU0Y2FmYTIwY2EyMDUwM2Y0YzRfODk4_c9c0156c-dab0-4f66-8ca2-fb048d07eb0d"
      unitRef="usd">47000000</us-gaap:BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther>
    <us-gaap:RevenueFromContractWithCustomerTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RleHRyZWdpb246NTQyN2ZkOWM3M2FhNDE2MDkzNWUwZjYzYTM2M2QyYTJfNTc0_370eaf6e-b1cb-4907-88cc-ea4a8953d073">Revenues&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;We operate in one business segment: human therapeutics. Therefore, results of our operations are reported on a consolidated basis for purposes of segment reporting, consistent with internal management reporting. Revenues by product and by geographic area, based on customers&#x2019; locations, are presented below. The majority of rest-of-world (ROW) revenues relates to products sold in Europe.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Revenues were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:32.818%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.133%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.133%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.823%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.133%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.133%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.133%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.144%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="33" style="border-bottom:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Three months ended September 30,&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;U.S.&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;ROW&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Total&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;U.S.&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;ROW&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Total&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Enbrel&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(etanercept)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,263&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;26&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,289&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,289&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;36&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,325&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Prolia&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt; (denosumab)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;530&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;273&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;803&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;478&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;223&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;701&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Otezla&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(apremilast)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;495&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;114&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;609&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;439&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;99&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;538&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;XGEVA&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt; (denosumab)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;372&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;145&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;517&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;363&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;118&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;481&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Neulasta&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(pegfilgrastim)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;360&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;55&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;415&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;484&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;71&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;555&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Aranesp&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(darbepoetin alfa)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;149&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;247&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;396&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;158&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;226&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;384&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Repatha&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(evolocumab)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;139&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;133&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;272&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;92&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;113&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;205&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;KYPROLIS&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(carfilzomib)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;198&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;95&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;293&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;173&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;87&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;260&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other products&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,052&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;674&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,726&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,142&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;513&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,655&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total product sales&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;(1)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,558&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,762&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,320&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,618&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,486&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,104&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other revenues&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;386&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;319&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total revenues&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,706&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,423&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="33" style="border-bottom:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Nine months ended September 30,&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;U.S.&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;ROW&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Total&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;U.S.&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;ROW&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Total&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;ENBREL&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,270&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;87&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,357&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,619&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;105&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,724&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Prolia&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,569&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;806&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,375&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,341&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;673&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,014&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Otezla&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,284&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;335&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,619&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,280&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;298&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,578&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;XGEVA&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt; &lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,061&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;412&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,473&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,036&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;361&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,397&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Neulasta&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,215&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;168&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,383&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,538&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;219&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,757&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Aranesp&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;409&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;709&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,118&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;489&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;704&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,193&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Repatha&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;421&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;423&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;844&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;331&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;303&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;634&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;KYPROLIS&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;547&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;277&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;824&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;527&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;266&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;793&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other products&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,059&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,974&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5,033&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,164&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,652&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,816&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total product sales&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;(1)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;12,835&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5,191&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;18,026&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;13,325&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,581&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;17,906&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other revenues&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,107&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;884&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total revenues&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;19,133&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;18,790&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-top:4pt;padding-left:13.5pt;text-indent:-13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;____________&lt;/span&gt;&lt;/div&gt;(1)&#160;&#160;&#160;&#160;Hedging gains and losses, which are included in product sales, were not material for the three and nine months ended September 30, 2021 and 2020.</us-gaap:RevenueFromContractWithCustomerTextBlock>
    <us-gaap:NumberOfOperatingSegments
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RleHRyZWdpb246NTQyN2ZkOWM3M2FhNDE2MDkzNWUwZjYzYTM2M2QyYTJfMjY_d2f6f122-54b4-4c80-b6bb-3931de2aab68"
      unitRef="segment">1</us-gaap:NumberOfOperatingSegments>
    <us-gaap:DisaggregationOfRevenueTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RleHRyZWdpb246NTQyN2ZkOWM3M2FhNDE2MDkzNWUwZjYzYTM2M2QyYTJfNTcy_dfd9d37f-0116-43c5-9d0b-9cefe5e1583f">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Revenues were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:32.818%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.133%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.133%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.823%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.133%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.133%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.133%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.144%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="33" style="border-bottom:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Three months ended September 30,&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;U.S.&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;ROW&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Total&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;U.S.&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;ROW&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Total&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Enbrel&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(etanercept)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,263&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;26&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,289&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,289&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;36&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,325&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Prolia&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt; (denosumab)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;530&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;273&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;803&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;478&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;223&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;701&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Otezla&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(apremilast)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;495&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;114&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;609&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;439&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;99&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;538&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;XGEVA&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt; (denosumab)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;372&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;145&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;517&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;363&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;118&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;481&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Neulasta&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(pegfilgrastim)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;360&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;55&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;415&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;484&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;71&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;555&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Aranesp&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(darbepoetin alfa)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;149&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;247&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;396&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;158&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;226&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;384&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Repatha&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(evolocumab)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;139&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;133&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;272&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;92&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;113&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;205&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;KYPROLIS&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(carfilzomib)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;198&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;95&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;293&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;173&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;87&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;260&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other products&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,052&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;674&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,726&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,142&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;513&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,655&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total product sales&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;(1)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,558&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,762&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,320&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,618&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,486&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,104&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other revenues&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;386&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;319&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total revenues&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,706&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,423&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="33" style="border-bottom:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Nine months ended September 30,&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;U.S.&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;ROW&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Total&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;U.S.&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;ROW&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Total&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;ENBREL&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,270&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;87&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,357&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,619&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;105&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,724&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Prolia&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,569&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;806&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,375&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,341&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;673&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,014&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Otezla&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,284&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;335&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,619&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,280&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;298&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,578&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;XGEVA&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt; &lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,061&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;412&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,473&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,036&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;361&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,397&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Neulasta&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,215&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;168&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,383&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,538&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;219&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,757&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Aranesp&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;409&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;709&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,118&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;489&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;704&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,193&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Repatha&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;421&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;423&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;844&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;331&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;303&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;634&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;KYPROLIS&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;547&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;277&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;824&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;527&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;266&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;793&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other products&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,059&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,974&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5,033&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,164&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,652&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,816&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total product sales&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;(1)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;12,835&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5,191&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;18,026&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;13,325&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,581&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;17,906&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other revenues&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,107&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;884&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total revenues&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;19,133&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;18,790&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-top:4pt;padding-left:13.5pt;text-indent:-13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;____________&lt;/span&gt;&lt;/div&gt;(1)&#160;&#160;&#160;&#160;Hedging gains and losses, which are included in product sales, were not material for the three and nine months ended September 30, 2021 and 2020.</us-gaap:DisaggregationOfRevenueTableTextBlock>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ic6cdb58f08f6497e9571e255839b182e_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMy0yLTEtMS0w_a561ef62-ed96-4bd9-9cc5-f742d187ab32"
      unitRef="usd">1263000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="idb19909eae6245c0b192e54299cbf115_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMy00LTEtMS0w_8b1f182c-93ff-4d5d-ae77-120db0bdf298"
      unitRef="usd">26000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="iff8d101adf4b402f8cf46cf5dcd93486_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMy02LTEtMS0w_dc78982f-4e0a-45e3-8af4-5ba7d7405767"
      unitRef="usd">1289000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i8c7cf69cd4834e9c85f4459b2de8d602_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMy04LTEtMS0w_1f157e3e-41d7-4fe6-940a-a9f279aaa72e"
      unitRef="usd">1289000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i881925882b374e84accf889451f21493_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMy0xMC0xLTEtMA_3520cc13-abfc-4ac4-83a8-7785fcbc6303"
      unitRef="usd">36000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i3580e2b0cb29470bad2033dc2b011286_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMy0xMi0xLTEtMA_1a962bd1-8391-41ca-8891-9417af9f48f3"
      unitRef="usd">1325000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i928ab90d0db745ea81bb2a93d965f16e_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNC0yLTEtMS0w_873e8465-16dc-45a0-b5ad-6e2912ad709d"
      unitRef="usd">530000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ia5bb4cc11d6c483d8309a8c954255a3c_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNC00LTEtMS0w_fc4e2f4f-a19d-46ba-894d-1257fbc617c0"
      unitRef="usd">273000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i5ad790cbfd31467bb8daa208b16d7e6e_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNC02LTEtMS0w_339ef089-0e1e-4662-9f09-3bc00e7f81e2"
      unitRef="usd">803000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="iee4b7620a6e94b15a0ee2efa21046c26_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNC04LTEtMS0w_14eaa7fb-e88d-41e9-b799-5bdece1a7536"
      unitRef="usd">478000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ic41a377f5b39468994f26d4f4fb0aa51_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNC0xMC0xLTEtMA_f87b722c-74ca-49a2-8296-8ec498ad5201"
      unitRef="usd">223000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i9e2067897ce84b959d0906d105ab21e8_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNC0xMi0xLTEtMA_d1d1ef08-a3d6-4552-96f1-80efbae1241b"
      unitRef="usd">701000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ica2c1ae056384bd5808311f2c76005bd_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNS0yLTEtMS0w_dbb652c1-e420-4c51-8c78-791c40d7b862"
      unitRef="usd">495000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i1e4fbb00243e4f62ba164169062363bd_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNS00LTEtMS0w_cfb60a81-f2dd-49c3-be3f-9a185a727b67"
      unitRef="usd">114000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="id03562c57df94c4695307d990b6d880d_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNS02LTEtMS0w_f2903dc8-661f-474a-ac39-b598fdf3c286"
      unitRef="usd">609000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ie59bcfe33b8147c0b1c58739ec6f4501_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNS04LTEtMS0w_1b45624b-6794-435d-b4d3-d7a4b10ccea3"
      unitRef="usd">439000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i7d0db737d136412cabc053873e3c0f55_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNS0xMC0xLTEtMA_7c7ec947-1867-4d96-b291-ea163ab10676"
      unitRef="usd">99000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i997de67b4d8041fd92aa65650ae56646_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNS0xMi0xLTEtMA_c572afa4-9934-402b-a98c-ce0631ad5f77"
      unitRef="usd">538000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i6be8feef3fae4c3ab81bc1a648281c8c_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi0yLTEtMS00MTE2Nw_77c5aecd-da84-46d0-ab54-70b25516d39d"
      unitRef="usd">372000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ib1e795008cb04855b4f4ada989eec622_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi00LTEtMS00MTE2Nw_3133836a-d541-48c6-ba53-a5f02530de85"
      unitRef="usd">145000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i7fb5d6e70e864ca9a24965da716a59f9_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi02LTEtMS00MTE2Nw_a49dd798-ede4-4bee-865d-561ce8d3c619"
      unitRef="usd">517000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i8f5c65603d3b495a97c04bb49c2930c7_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi04LTEtMS00MTE2Nw_e99be74a-9872-46b9-af06-6208a31253ed"
      unitRef="usd">363000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="if2f93bdf48274317b1da0bbaad739897_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi0xMC0xLTEtNDExNjc_f2bb95b3-0ec6-4982-a71f-361eeafc185a"
      unitRef="usd">118000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i6d80e26ad167494498b23e0ca5271458_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi0xMi0xLTEtNDExNjc_fe991410-454d-4cd6-a65c-b20ad0f4c368"
      unitRef="usd">481000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i17187759eba94aadb3d31a3510ebf19e_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi0yLTEtMS0w_5442f293-8b65-4935-8388-e9a2a4a8837a"
      unitRef="usd">360000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i641be115cab64df981d42cdd9261ce71_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi00LTEtMS0w_73cf3518-7959-4ea0-917e-d00c3b93db17"
      unitRef="usd">55000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i368f295d54bd4525bb8eb6714d3d0066_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi02LTEtMS0w_98eb94ca-231f-4d75-8224-69aadad33060"
      unitRef="usd">415000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="icf361ee93a5a459fb961382bfdaab897_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi04LTEtMS0w_9f71d935-e7d0-4df8-8070-e4ba0eddaf59"
      unitRef="usd">484000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="iae3f58a4ca5c4ee6b7a5efa557d3239e_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi0xMC0xLTEtMA_3dfd6920-b8c7-4236-9504-5aac6f14a3a1"
      unitRef="usd">71000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i89c0f0d97cef4bd6b1184caf279f571a_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfNi0xMi0xLTEtMA_6fb9878b-7e53-4857-81cb-49d978ddbc9c"
      unitRef="usd">555000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i739f696b931d4702b3df5ae6ca746716_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOC0yLTEtMS0w_69e5f02e-8ab5-451c-92ef-91ffd61b1e2d"
      unitRef="usd">149000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="if968e6327f794c59a9ba65fc3208a8f6_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOC00LTEtMS0w_c1f8f87c-ad0f-4b88-9393-715a8322bb17"
      unitRef="usd">247000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ic9d9abb7215c47c2a1aca1be0668980f_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOC02LTEtMS0w_bc9f5b44-92e2-4768-af0b-26f866c7226a"
      unitRef="usd">396000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i5b3ef1a8e7f545cfa45814ef6cc1e9ef_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOC04LTEtMS0w_9690b1e8-5649-4ad1-8093-c2507a856143"
      unitRef="usd">158000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i65474b7854d64aadbcea001bcca67fcc_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOC0xMC0xLTEtMA_9905eafc-6ed5-4a5b-8fb1-bc80a460269f"
      unitRef="usd">226000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="id84e814556764ab79f45c36978bd96e4_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOC0xMi0xLTEtMA_953aaef0-0e80-41af-9074-272d9e0ef5f2"
      unitRef="usd">384000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i39b00b7d625e4f6487ec0db17bdc442d_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOS0yLTEtMS0w_1df4398f-ef0a-49a7-ac99-3062bd8ffedc"
      unitRef="usd">139000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i817db5726ac748d4bd491dbef24298e8_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOS00LTEtMS0w_37c2b8a6-bca5-4af5-a74c-74c606323fd6"
      unitRef="usd">133000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="if48659bf944e4492a4dafa719e7083d0_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOS02LTEtMS0w_7c5b8761-cf6b-4747-929e-a19d503707c0"
      unitRef="usd">272000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i7b514b2a404649a58ac1b9f9087c9ed6_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOS04LTEtMS0w_ebc7b613-0789-4097-9bd5-9cb99ac411a8"
      unitRef="usd">92000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i69c93666703d4eac86caffd587b7db7d_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOS0xMC0xLTEtMA_146205d3-6142-4af6-af71-384613797538"
      unitRef="usd">113000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i0dea61c77564492ab39c0a6ee2a71ffb_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfOS0xMi0xLTEtMA_dfc12f87-a9d7-42f2-8d85-162ad9ad9720"
      unitRef="usd">205000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i643c94b54a124674bdf0a819e67e429b_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTAtMi0xLTEtMA_c8681913-9e91-4175-b5a9-baa6ed28dcc9"
      unitRef="usd">198000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i21f6d8435c474c6980866635aeee71e9_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTAtNC0xLTEtMA_bc36699a-cbba-48fa-8dfa-ab6411766938"
      unitRef="usd">95000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i0c97db9ff3494e8c8961a94b3979974b_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTAtNi0xLTEtMA_b4c39a63-a743-4a8d-9f28-a1fc8a55c9d4"
      unitRef="usd">293000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i36d299d1d5a642cca156e5411c4b4fc8_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTAtOC0xLTEtMA_f08e7698-834b-432e-aee5-03d7331a76fc"
      unitRef="usd">173000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ifadfb5ce284249b49c5b541e46f8fd6d_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTAtMTAtMS0xLTA_cfcf768a-dc7b-4272-a936-3a9a0b9fe8d7"
      unitRef="usd">87000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ibb9fffae57f44694bf945745287d733a_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTAtMTItMS0xLTA_3d23b444-4040-436b-b4c6-b0a9ae2dea29"
      unitRef="usd">260000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i2f0871bad93240bd851a8f0aaa387350_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTEtMi0xLTEtMA_afbbc328-a687-4503-b453-abf59edf2bbb"
      unitRef="usd">1052000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i10acdfdcf69c40c2a0bdc6d3e81fb337_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTEtNC0xLTEtMA_9688a464-b0b7-4cd9-9725-9601688b0bf0"
      unitRef="usd">674000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i23817bdf825e4ae1ac3362ea0639d136_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTEtNi0xLTEtMA_b6e5b8ff-7884-4aa4-af05-d10e42d995eb"
      unitRef="usd">1726000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i0beb71107b234faea29110b3fa9d8a98_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTEtOC0xLTEtMA_f8c5d900-ad67-4229-b6ad-10f387e5cce2"
      unitRef="usd">1142000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ic81b8501b6db4aee88091da6a3afdf07_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTEtMTAtMS0xLTA_eea2bd1a-6308-431b-a04e-ea2a816ca8d0"
      unitRef="usd">513000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="if807b6245b86445088eb952987a6b469_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTEtMTItMS0xLTA_e654a972-f8d8-4d3a-865c-b819fdad45fc"
      unitRef="usd">1655000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ia3c6be49d4364b1f9f7490f5b324e697_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTItMi0xLTEtMA_9c788d5a-b307-4d9e-82df-09062b90c22e"
      unitRef="usd">4558000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i2032ce010c324b94be367952c9e7ba79_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTItNC0xLTEtMA_ff609518-d18b-4c30-9364-c2c58ba7ecf7"
      unitRef="usd">1762000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i237db287808149dc88791dd0402e8c8d_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTItNi0xLTEtMA_07e2dc7d-ccae-4e9b-b244-48e590bbc993"
      unitRef="usd">6320000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i8b0da7f54b9d44ec896bac0ef1d0eb58_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTItOC0xLTEtMA_837333e1-b56f-44ad-8364-66b73356d31a"
      unitRef="usd">4618000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i05cbea6753bb40cc89759fbeb6e01550_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTItMTAtMS0xLTA_3108c977-2357-431a-94a2-ee1de3c7a58a"
      unitRef="usd">1486000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="icc3aae43096e4ee2941dfecfdc9776ad_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTItMTItMS0xLTA_68aa43f2-1c2b-45d2-884e-3106ba775070"
      unitRef="usd">6104000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i488eb65c564543e1895d64ea848f40c4_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTMtNi0xLTEtMA_29185add-a4c6-49ea-ae8c-145a10a45d76"
      unitRef="usd">386000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="id0ffdac343f944aaa636865f0a68567e_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTMtMTItMS0xLTA_36dab01a-0276-46b5-af94-aad9417b485c"
      unitRef="usd">319000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTQtNi0xLTEtMA_348c9739-fe62-41bb-98e2-ad33dc291ba2"
      unitRef="usd">6706000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTQtMTItMS0xLTA_7ff13a12-b0d0-42c3-836b-7cb434c7cab3"
      unitRef="usd">6423000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ia48b8184147044458082feb5ea147e49_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTktMi0xLTEtMA_8954affe-fbe3-423f-b816-4124c1a09c16"
      unitRef="usd">3270000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i99ffbf75ddf84e1e9245421a8c01d767_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTktNC0xLTEtMA_c4510e0e-1442-496c-b295-36d18ccdbae2"
      unitRef="usd">87000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="idab45a332369432d9ebd6f50b96a8f56_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTktNi0xLTEtMA_102d5de0-7bb3-4b3c-8376-b787d68de5bb"
      unitRef="usd">3357000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ica6caa6433a24945a279239a702b2abf_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTktOC0xLTEtMA_b3c838af-8f5f-4521-89c4-f7180cc4efe2"
      unitRef="usd">3619000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ic1bb05a1b59b4da5902e961b2a5533a0_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTktMTAtMS0xLTA_9831cf18-3f13-4e05-9245-debff2ad3ea1"
      unitRef="usd">105000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i7cbcc55bfaff415a96eaa73c996dbb6a_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMTktMTItMS0xLTA_3e731624-d05f-41a3-9237-142ec6d216de"
      unitRef="usd">3724000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="iaf3073b6b8e349c9b88d3cb4f719e628_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjAtMi0xLTEtMA_0e5d3e25-dfa5-429e-86e7-8c92e73cf90e"
      unitRef="usd">1569000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ib9e71fbc76704655955f107a3a191a9c_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjAtNC0xLTEtMA_017390a3-f89d-4294-8c96-a7935281e098"
      unitRef="usd">806000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ide3ecdc601c44f8d89456132330e9af2_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjAtNi0xLTEtMA_a8a214da-1acd-46cf-b594-35928f1a7662"
      unitRef="usd">2375000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i17357cd18fe541d0a042e9ee59c93b38_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjAtOC0xLTEtMA_c1fe4ea8-0a9a-40b3-a7e8-c5c80f3c21fd"
      unitRef="usd">1341000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ib3777a2c9f034e97919676bb7754de25_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjAtMTAtMS0xLTA_35d6002e-5f5f-4a09-ab13-449ade21fc82"
      unitRef="usd">673000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i6b5f2a9043d945b08ec0167f3cfed9f2_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjAtMTItMS0xLTA_960e28af-0fdf-4f35-a7ae-765877065a15"
      unitRef="usd">2014000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i95957399b3a14e7383788a66404fcbbb_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjEtMi0xLTEtMA_71c15aba-8e9c-4e05-ba7f-45dc025f9b28"
      unitRef="usd">1284000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i78293d5fa71b41ef9cc01a231545bab2_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjEtNC0xLTEtMA_c47a4321-c0e9-4bf4-bf1f-53d1520c398b"
      unitRef="usd">335000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i195420e0531242db9f936a0127259be3_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjEtNi0xLTEtMA_cb75c058-d9d1-4881-8149-af0fcc8d154a"
      unitRef="usd">1619000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="if0fb79f0bfbc4e51b7cb42fd1d71c840_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjEtOC0xLTEtMA_fcf2000b-cc7b-4db5-a7ee-0d32447a1f46"
      unitRef="usd">1280000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i68bf0dc18c0d4ffa9e9a898ff74c54f1_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjEtMTAtMS0xLTA_5ec06311-14c7-4922-ade7-a032dcb5e99f"
      unitRef="usd">298000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ibe1bd36ce26a43fe9cb844c7326c4e54_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjEtMTItMS0xLTA_b73ccc46-8b37-4a38-9dbd-912cf3bea94f"
      unitRef="usd">1578000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i7da33cf805a445869662f5abc2106d6d_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItMi0xLTEtNDExNTc_5cafc24c-d0c3-40eb-b409-e6eae599631c"
      unitRef="usd">1061000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ia6106c345460401c9e03019b7c080699_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItNC0xLTEtNDExNTc_b15a0936-cae3-4f68-83b9-535ad294ee25"
      unitRef="usd">412000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i443bd36291d548a0aa9856e73206eac6_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItNi0xLTEtNDExNTc_a58942a0-184b-43d7-8708-9fff02f71ba0"
      unitRef="usd">1473000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="id7ca09709e904974a92ad3adb8b9fd77_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItOC0xLTEtNDExNTc_7f9e608b-7653-45c5-9bb6-5ea16cddbfce"
      unitRef="usd">1036000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i98005524cd124b8c966a68f6bdcfb8fc_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItMTAtMS0xLTQxMTU3_6cd8c491-1bf9-4722-8c78-2673b2bffdce"
      unitRef="usd">361000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i5b4401a3903c4c908d2eb7fe95caad21_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItMTItMS0xLTQxMTU3_52c2c58e-bfd3-4db6-850d-06f33972d3b6"
      unitRef="usd">1397000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i3cd61c0be22f4420b7238ce5a6df9130_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItMi0xLTEtMA_a27038ea-44f9-417d-8fcc-adb9adea2083"
      unitRef="usd">1215000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="iae6381714cfe468aa29ce147540ec7e9_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItNC0xLTEtMA_2a195e2f-2124-485b-8d72-88016c62dee2"
      unitRef="usd">168000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i96040b94405a4bd1a72890459e71ee00_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItNi0xLTEtMA_4ea8dbfa-42cb-4f06-ba86-158f2b8188a0"
      unitRef="usd">1383000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="iad909099174b42f681a09827cb78f0a7_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItOC0xLTEtMA_81bf638c-49e5-4edd-a09e-bf2c182c65e5"
      unitRef="usd">1538000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i9445f98f484747b89af2e9d73ea09d95_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItMTAtMS0xLTA_1257a287-8ecc-4c4b-902d-900be84c0998"
      unitRef="usd">219000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ib01fa4a797464e63b788127b5705e442_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjItMTItMS0xLTA_5bacfd06-c605-42a9-8f52-556908244ceb"
      unitRef="usd">1757000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i4f38a5540cd04d718fff14e7bd440bf3_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjQtMi0xLTEtMA_87d1094a-d347-429c-b2a9-a262c2765f5e"
      unitRef="usd">409000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ia48c696724e24052ae23b516c63d79e2_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjQtNC0xLTEtMA_da7aef08-6ad2-4f4a-a471-3edea995bb5f"
      unitRef="usd">709000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ic91169bf44324e9c8beba26b3f9827e7_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjQtNi0xLTEtMA_f8d96815-b389-410b-8fe7-6e28538134df"
      unitRef="usd">1118000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i749f9c098fc64abb9167bd96645abed7_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjQtOC0xLTEtMA_78552b2f-db5c-4b5f-afc4-2a436fe06380"
      unitRef="usd">489000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="id2cb108abc1b4ddc9555fa47ab4e573b_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjQtMTAtMS0xLTA_d3854214-3564-4b2e-b1ab-32e263494abf"
      unitRef="usd">704000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i576d061a6ae043e0829b0988a7faa3ec_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjQtMTItMS0xLTA_295bb39a-255f-4c9a-9692-09583235be6c"
      unitRef="usd">1193000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ic52c02bf054740ada11032b24246ae68_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjUtMi0xLTEtMA_dc114cea-9539-4ea0-96c2-801610b7a8c9"
      unitRef="usd">421000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ic6cc0b13a201477e8bdc3a92299b7b68_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjUtNC0xLTEtMA_0661c60c-4bd0-4bc9-ba71-00b386bf9df5"
      unitRef="usd">423000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="id29b4587abfe4026b9589b04316507cb_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjUtNi0xLTEtMA_f2fd7175-45ab-48d6-9b6d-8cd9eb69ea36"
      unitRef="usd">844000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i99a4a03013b04d41935e841bd095d3a7_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjUtOC0xLTEtMA_b9dc6b17-b5b0-4d97-9263-2a8c2060928d"
      unitRef="usd">331000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i6a2c38f1abb049d190286ec739f3d8ae_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjUtMTAtMS0xLTA_94618f28-b884-4041-ae04-0c50c2aa3206"
      unitRef="usd">303000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ieb422a6656b54be5afd83d1c3557841c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjUtMTItMS0xLTA_42fb5881-f460-4d1d-83ca-a418ea6962be"
      unitRef="usd">634000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="iee523348acf64084b9744fc397411af6_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjYtMi0xLTEtMA_b8a91d72-8bde-4441-8322-fe0149780a9d"
      unitRef="usd">547000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ie2fb5db5ef234ceba2e63133b46811d9_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjYtNC0xLTEtMA_32281533-01a3-41c9-8b4c-4da438a68976"
      unitRef="usd">277000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ia1236d7f1db54d0cbbb4bb10634d9cbd_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjYtNi0xLTEtMA_5a42eed2-d4bf-4a68-a8be-9827b397df85"
      unitRef="usd">824000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i700316332e8941abafe598d080cee8ed_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjYtOC0xLTEtMA_468c318f-d52d-41f7-8258-72d6fd505d3f"
      unitRef="usd">527000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i2237615b64f7401e880801b52e994daf_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjYtMTAtMS0xLTA_5a0e7adc-68e3-4883-8057-f4a78eb3f640"
      unitRef="usd">266000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i3367f489225f42e490b5ec1bd448da76_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjYtMTItMS0xLTA_6922681d-e1c3-435b-b2b4-f7cd69b50351"
      unitRef="usd">793000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ie4393fb731674dae95e49ebf43c2dc17_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjctMi0xLTEtMA_492bfd42-aa3c-4d00-ba81-0fadee3c2458"
      unitRef="usd">3059000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i2d608ed82a0642d2bd3d2585175ab0df_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjctNC0xLTEtMA_a8d80599-153f-40e7-ba5e-c81b8906dd49"
      unitRef="usd">1974000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i7ec4a6f423c548c287970aa87131e9c9_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjctNi0xLTEtMA_dc9bc526-5216-41a1-9c28-263aefb22c49"
      unitRef="usd">5033000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i277af735bdea4ca1ad4911bd0724214d_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjctOC0xLTEtMA_300dfc12-33ac-48f0-a22e-4ca6c8d0dd8c"
      unitRef="usd">3164000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i547f36d7acb3432789479ca670e2143f_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjctMTAtMS0xLTA_db5d19a5-5b45-4d4e-89dd-5abe60f4d180"
      unitRef="usd">1652000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i6ddfacf19b5b4634890a1b86f11498d4_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjctMTItMS0xLTA_b6056282-36d2-4fdf-a33b-0db365915907"
      unitRef="usd">4816000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="iec4ac6803eb24d47ae70292430854aee_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjgtMi0xLTEtMA_09e2f6f8-ad00-428a-9b4f-011172c1187d"
      unitRef="usd">12835000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i11c711a9331e402aa04c6f1100a9a662_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjgtNC0xLTEtMA_2900f3d9-12bb-49cd-913d-1ddf2e5f37a6"
      unitRef="usd">5191000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i3eb445431b634cc6b3e61727cef7b877_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjgtNi0xLTEtMA_4b41e01e-9e92-4267-b6ec-b1eca7e18ee0"
      unitRef="usd">18026000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="icc040f113aa74ff9aa98ca66ae336cbf_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjgtOC0xLTEtMA_51698992-20db-4094-b016-5a557fcee687"
      unitRef="usd">13325000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i03039f45f78c4280b4623c349760790f_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjgtMTAtMS0xLTA_2ae2eec9-f4c2-4130-9d99-fe59e6213598"
      unitRef="usd">4581000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i556e038dae96477cbe84bc1653ed5883_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjgtMTItMS0xLTA_65c0704c-5dd2-4daf-82cd-67e3a72efa68"
      unitRef="usd">17906000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="iddf8eed0ade74615b203cae47895e098_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjktNi0xLTEtMA_c64cd7a6-5ec6-46b1-9574-3ac1388b7074"
      unitRef="usd">1107000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ia3ba4d704ab343159b80e5ecde0bf68b_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMjktMTItMS0xLTA_82599f48-6b55-4fa9-b5a7-a463434ea4b0"
      unitRef="usd">884000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMzAtNi0xLTEtMA_f34c55db-1186-4930-b8de-f183d77f5549"
      unitRef="usd">19133000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80MC9mcmFnOjU0MjdmZDljNzNhYTQxNjA5MzVlMGY2M2EzNjNkMmEyL3RhYmxlOjBmMzI0ODkzN2Y5ZjQ0MWJhZDkwOWJiNDIzMTY5OTVlL3RhYmxlcmFuZ2U6MGYzMjQ4OTM3ZjlmNDQxYmFkOTA5YmI0MjMxNjk5NWVfMzAtMTItMS0xLTA_44e23343-e94c-405e-8195-c7e1d7599d46"
      unitRef="usd">18790000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:IncomeTaxDisclosureTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfNDc4Nw_e66353e8-9815-4a8f-86ac-215e0de6746f">Income taxes&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The effective tax rate for the three and nine months ended September 30, 2021, was 12.6% for both periods, compared with rates of 8.4% and 9.7%, respectively, for the corresponding periods of the prior year.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The increase in our effective tax rate for the three and nine months ended September 30, 2021, was primarily due to the non-deductible IPR&amp;amp;D expense arising from the acquisition of Five Prime and prior year favorable items partially offset by a change in earnings mix. The effective tax rates differ from the federal statutory rate primarily as a result of foreign earnings from the Company&#x2019;s operations conducted in Puerto Rico, a territory of the United States treated as a foreign jurisdiction for U.S. tax purposes, that are subject to a tax incentive grant through 2035. In addition, the Company&#x2019;s operations conducted in Singapore are subject to a tax incentive grant through 2034. These foreign earnings are also subject to U.S. tax at a reduced rate of 10.5%.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The U.S. territory of Puerto Rico imposes an excise tax on the gross intercompany purchase price of goods and services from our manufacturer in Puerto Rico. The rate of 4% is effective through December 31, 2027. We account for the excise tax as a manufacturing cost that is capitalized in inventory and expensed in cost of sales when the related products are sold. For U.S. income tax purposes, the excise tax results in foreign tax credits that are generally recognized in our provision for income taxes when the excise tax is incurred.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;One or more of our legal entities file income tax returns in the U.S. federal jurisdiction, various U.S. state jurisdictions and certain foreign jurisdictions. Our income tax returns are routinely examined by tax authorities in those jurisdictions. Significant disputes may arise with tax authorities involving issues regarding the timing and amount of deductions, the use of tax credits and allocations of income and expenses among various tax jurisdictions because of differing interpretations of tax laws, regulations and relevant facts. In 2017, we received a Revenue Agent Report (RAR) and a modified RAR from the Internal Revenue Service (IRS) for the years 2010, 2011 and 2012 proposing significant adjustments that primarily relate to the allocation of profits between certain of our entities in the United States and the U.S. territory of Puerto Rico. We disagreed with the proposed adjustments and calculations and pursued a resolution with the IRS administrative appeals office. As previously reported, we were unable to reach resolution with the IRS appeals office. In July 2021, we filed a petition in the U.S. Tax Court to contest two duplicate Statutory Notices of Deficiency (Notices) for 2010, 2011 and 2012 that we received in May and July 2021. The duplicate Notices seek to increase our U.S. taxable income by an amount that would result in additional federal tax of approximately $3.6&#160;billion, plus interest. Any additional tax that could be imposed would be reduced by up to approximately $900&#160;million of repatriation tax previously accrued on our foreign earnings. In any event, we firmly believe that the IRS&#x2019;s positions in the Notices are without merit, and we will vigorously contest the Notices through the judicial process.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:112%"&gt;In addition, in 2020, we received an RAR and a modified RAR from the IRS for the years 2013, 2014 and 2015 also proposing significant adjustments that primarily relate to the allocation of profits between certain of our entities in the United States and the U.S. territory of Puerto Rico, similar to those proposed for the years 2010, 2011 and 2012. We disagree with the proposed adjustments and calculations and have been pursuing resolution with the IRS administrative appeals office. As a consequence of the Tax Court litigation for the 2010-2012 period, the IRS administrative appeals office recently informed us that it does not plan to engage in discussions at this time regarding the allocation of profits between our entities in the United States and the U.S. territory of Puerto Rico for the 2013-2015 period. We are currently under examination by the IRS for the years 2016, 2017 and 2018. We are also currently under examination by a number of other state and foreign tax jurisdictions.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:112%"&gt;Final resolution of these complex matters is not likely within the next 12 months. We believe our accrual for income tax liabilities is appropriate based on past experience, interpretations of tax law, application of the tax law to our facts and judgments about potential actions by tax authorities; however, due to the complexity of the provision for income taxes and uncertain resolution of these matters, the ultimate outcome of any tax matters may result in payments substantially greater than amounts accrued and could have a material adverse impact on our condensed consolidated financial statements. We are no longer subject to U.S. federal income tax examinations for the years ended on or before December 31, 2009.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;During the three and nine months ended September 30, 2021, the gross amounts of our unrecognized tax benefits (UTBs) increased $70 million and $180&#160;million, respectively, as a result of tax positions taken during the current year. Substantially all of the UTBs as of September 30, 2021, if recognized, would affect our effective tax rate.&lt;/span&gt;&lt;/div&gt;</us-gaap:IncomeTaxDisclosureTextBlock>
    <us-gaap:EffectiveIncomeTaxRateContinuingOperations
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="3"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfNjk_199677fc-029b-424e-80fc-3aa111545926"
      unitRef="number">0.126</us-gaap:EffectiveIncomeTaxRateContinuingOperations>
    <us-gaap:EffectiveIncomeTaxRateContinuingOperations
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="3"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfNjk_2f9649e1-39a4-41f7-aa1d-6db6e3f6b37b"
      unitRef="number">0.126</us-gaap:EffectiveIncomeTaxRateContinuingOperations>
    <us-gaap:EffectiveIncomeTaxRateContinuingOperations
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="3"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfMTA4_1eae16b8-ad7a-410e-823d-8c503b8399c2"
      unitRef="number">0.084</us-gaap:EffectiveIncomeTaxRateContinuingOperations>
    <us-gaap:EffectiveIncomeTaxRateContinuingOperations
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="3"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfMTA4_ee081196-76b8-4a29-89bc-d8c0400355a1"
      unitRef="number">0.084</us-gaap:EffectiveIncomeTaxRateContinuingOperations>
    <us-gaap:EffectiveIncomeTaxRateContinuingOperations
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="3"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfMTE1_db289517-e979-46f8-8cad-09916fcd1e41"
      unitRef="number">0.097</us-gaap:EffectiveIncomeTaxRateContinuingOperations>
    <amgn:ProposedAdditionalIncomeTax
      contextRef="i91b6753ab42449599e1e80924db35109_I20210531"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfMjc3OQ_e2c74c64-38af-420a-a6d8-67fff15b2192"
      unitRef="usd">3600000000</amgn:ProposedAdditionalIncomeTax>
    <amgn:RepatriationTaxOnProposedAdditionalTax
      contextRef="i91b6753ab42449599e1e80924db35109_I20210531"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfMjg3OQ_37ae7f3b-66f3-423b-8e29-bef1149679df"
      unitRef="usd">900000000</amgn:RepatriationTaxOnProposedAdditionalTax>
    <us-gaap:UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfNDU5Mg_20a3a5da-143f-488c-bdd0-557530ae5c5b"
      unitRef="usd">70000000</us-gaap:UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions>
    <us-gaap:UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80My9mcmFnOmExYzJiNDJmMmU5ZjQ2YzdiMGEzZTU1ZDljOTc0MWFiL3RleHRyZWdpb246YTFjMmI0MmYyZTlmNDZjN2IwYTNlNTVkOWM5NzQxYWJfNDU5OQ_8a4e05cf-d572-4a20-b2cb-342d727abb0c"
      unitRef="usd">180000000</us-gaap:UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions>
    <us-gaap:EarningsPerShareTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RleHRyZWdpb246YTMyZjgyN2MzYTkwNGI3MzliMzBjOGVhODVkZDc3ZTlfNzQ1_e717e76a-d832-4fef-9358-6b59c0a7b49d">Earnings per share&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The computation of basic earnings per share (EPS) is based on the weighted-average number of our common shares outstanding. The computation of diluted EPS is based on the weighted-average number of our common shares outstanding and dilutive potential common shares, which primarily include shares that may be issued under our stock option, restricted stock and performance unit award programs (collectively, dilutive securities), as determined by using the treasury stock method.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The computations for basic and diluted EPS were as follows (in millions, except per-share data):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:center"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:45.829%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.619%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.619%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.619%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.624%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:120%"&gt;Three months ended&lt;br/&gt;September 30,&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Nine months ended&lt;br/&gt;September 30,&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Income (Numerator):&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Net income for basic and diluted EPS&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,884&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,021&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,994&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5,649&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Shares (Denominator):&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Weighted-average shares for basic EPS&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;567&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;585&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;572&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;588&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Effect of dilutive securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Weighted-average shares for diluted EPS&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;570&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;589&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;576&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;592&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Basic EPS&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.32&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.45&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6.98&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9.61&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Diluted EPS&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.31&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.43&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6.93&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9.54&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;For the three and nine months ended September 30, 2021 and 2020, the number of antidilutive employee stock-based awards excluded from the computation of diluted EPS was not significant.&lt;/span&gt;&lt;/div&gt;</us-gaap:EarningsPerShareTextBlock>
    <us-gaap:ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RleHRyZWdpb246YTMyZjgyN2MzYTkwNGI3MzliMzBjOGVhODVkZDc3ZTlfNzYz_050c7f0e-f8a5-40ff-af6a-4eb1010ae3f6">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The computations for basic and diluted EPS were as follows (in millions, except per-share data):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:center"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:45.829%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.619%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.619%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.619%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.624%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:120%"&gt;Three months ended&lt;br/&gt;September 30,&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Nine months ended&lt;br/&gt;September 30,&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Income (Numerator):&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Net income for basic and diluted EPS&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,884&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,021&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,994&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5,649&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Shares (Denominator):&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Weighted-average shares for basic EPS&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;567&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;585&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;572&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;588&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Effect of dilutive securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Weighted-average shares for diluted EPS&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;570&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;589&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;576&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;592&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Basic EPS&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.32&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.45&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6.98&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9.61&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Diluted EPS&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.31&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.43&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6.93&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9.54&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</us-gaap:ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock>
    <us-gaap:NetIncomeLoss
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMy0xLTEtMS0w_e3da7c8d-ac98-4e86-9fb9-e0024d20494d"
      unitRef="usd">1884000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMy0zLTEtMS0w_1ff34e75-a045-439a-a1f9-6e33b6cc1d0b"
      unitRef="usd">2021000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMy01LTEtMS0w_cdf928ff-1c82-44ca-80ef-02671f90d69a"
      unitRef="usd">3994000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMy03LTEtMS0w_036cba6f-8fd2-4bec-8054-1fd73d635bcc"
      unitRef="usd">5649000000</us-gaap:NetIncomeLoss>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNi0xLTEtMS0w_ad16d9f0-7086-44b4-bf05-42784325bfe0"
      unitRef="shares">567000000</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNi0zLTEtMS0w_f477fb3f-36cb-4542-9b45-b8bbee5bbc62"
      unitRef="shares">585000000</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNi01LTEtMS0w_1a5d64eb-10c8-4adc-b514-2493ff0ce933"
      unitRef="shares">572000000</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberOfSharesOutstandingBasic
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNi03LTEtMS0w_c3d376fa-eb20-4afb-b3dd-986288434de2"
      unitRef="shares">588000000</us-gaap:WeightedAverageNumberOfSharesOutstandingBasic>
    <us-gaap:WeightedAverageNumberDilutedSharesOutstandingAdjustment
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNy0xLTEtMS0w_13ed1f45-c602-45cb-9d72-cdeff44bf6df"
      unitRef="shares">3000000</us-gaap:WeightedAverageNumberDilutedSharesOutstandingAdjustment>
    <us-gaap:WeightedAverageNumberDilutedSharesOutstandingAdjustment
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNy0zLTEtMS0w_cc019954-9477-45a4-b38a-8d660ad3a55c"
      unitRef="shares">4000000</us-gaap:WeightedAverageNumberDilutedSharesOutstandingAdjustment>
    <us-gaap:WeightedAverageNumberDilutedSharesOutstandingAdjustment
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNy01LTEtMS0w_c30e0c25-29f2-4136-9dfc-370dd4f247f0"
      unitRef="shares">4000000</us-gaap:WeightedAverageNumberDilutedSharesOutstandingAdjustment>
    <us-gaap:WeightedAverageNumberDilutedSharesOutstandingAdjustment
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfNy03LTEtMS0w_fb572659-14f7-450c-9302-4060413a0c31"
      unitRef="shares">4000000</us-gaap:WeightedAverageNumberDilutedSharesOutstandingAdjustment>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfOC0xLTEtMS0w_319e8e6e-2ae5-4a79-b412-21b6a3a8cb8a"
      unitRef="shares">570000000</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfOC0zLTEtMS0w_1b9dfc19-45e1-4782-b270-f7914f5926be"
      unitRef="shares">589000000</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfOC01LTEtMS0w_5bb39a2a-860d-416d-acdc-82976f5575dc"
      unitRef="shares">576000000</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfOC03LTEtMS0w_55b93733-f88f-4b08-9f89-e4b67cdb367c"
      unitRef="shares">592000000</us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding>
    <us-gaap:EarningsPerShareBasic
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTAtMS0xLTEtMA_598d8279-f390-4e5d-bca6-140305d7fdc4"
      unitRef="usdPerShare">3.32</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareBasic
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTAtMy0xLTEtMA_149ec296-de56-4b75-9749-8258e55dd424"
      unitRef="usdPerShare">3.45</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareBasic
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTAtNS0xLTEtMA_1d598ab2-152a-42ca-9729-4c62189dfa26"
      unitRef="usdPerShare">6.98</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareBasic
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTAtNy0xLTEtMA_01454821-0064-444b-a206-a3a6b6de86f0"
      unitRef="usdPerShare">9.61</us-gaap:EarningsPerShareBasic>
    <us-gaap:EarningsPerShareDiluted
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTEtMS0xLTEtMA_c2c2c858-601b-4d41-b70a-16c22292d755"
      unitRef="usdPerShare">3.31</us-gaap:EarningsPerShareDiluted>
    <us-gaap:EarningsPerShareDiluted
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTEtMy0xLTEtMA_ed715498-c2e5-4194-9c16-d8fc72e42f0d"
      unitRef="usdPerShare">3.43</us-gaap:EarningsPerShareDiluted>
    <us-gaap:EarningsPerShareDiluted
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTEtNS0xLTEtMA_b89629b3-46a6-4e8a-97cd-8b528d37a977"
      unitRef="usdPerShare">6.93</us-gaap:EarningsPerShareDiluted>
    <us-gaap:EarningsPerShareDiluted
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80Ni9mcmFnOmEzMmY4MjdjM2E5MDRiNzM5YjMwYzhlYTg1ZGQ3N2U5L3RhYmxlOjA3N2M3NmJlNTBkMDQzZDA5YWFmODMzYTlhNTgxMzNjL3RhYmxlcmFuZ2U6MDc3Yzc2YmU1MGQwNDNkMDlhYWY4MzNhOWE1ODEzM2NfMTEtNy0xLTEtMA_17aae5b6-c5d8-48a1-bda3-91804f1637e9"
      unitRef="usdPerShare">9.54</us-gaap:EarningsPerShareDiluted>
    <us-gaap:CollaborativeArrangementDisclosureTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xMDg4L2ZyYWc6OGY5MDIzYmQyNTAwNDI0YjhlMWZhNzAzOTE2NjBlM2UvdGV4dHJlZ2lvbjo4ZjkwMjNiZDI1MDA0MjRiOGUxZmE3MDM5MTY2MGUzZV83Njk2NTgxNDA3MTUw_80ab5851-3aee-4df1-b20e-1938494e140f">Collaborations&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;On July 30, 2021, we closed our collaboration and licensing agreement with Kyowa Kirin Co., Ltd. (KKC) to jointly develop and commercialize an anti-OX40 fully human monoclonal antibody (AMG 451) worldwide, except in Japan. AMG 451 is for the treatment of atopic dermatitis, with potential in other autoimmune diseases.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Under the terms of the agreement, we will lead the global development, manufacturing and commercialization of AMG 451, except in Japan. KKC will co-promote AMG 451 with Amgen in the United States and have opt-in rights to co-promote AMG 451 in various other markets outside the United States, including in Europe and Asia. &lt;/span&gt;&lt;/div&gt;We made an upfront payment of $400&#160;million to KKC that was recognized in Research and development (R&amp;amp;D) expense in the third quarter of 2021. Amgen and KKC will share equally the global development costs, except in Japan, and the U.S. commercialization costs. Outside of the United States and Japan, any commercialization costs incurred by KKC will be reimbursed by Amgen. We may also be required to make milestone payments of up to $850&#160;million contingent upon the achievement of certain regulatory events and commercial thresholds. We will also pay KKC significant double-digit royalties on global sales, except in Japan.</us-gaap:CollaborativeArrangementDisclosureTextBlock>
    <amgn:UpFrontPayment
      contextRef="icb5563aa4d0b4e68b3266d16db71f2a1_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xMDg4L2ZyYWc6OGY5MDIzYmQyNTAwNDI0YjhlMWZhNzAzOTE2NjBlM2UvdGV4dHJlZ2lvbjo4ZjkwMjNiZDI1MDA0MjRiOGUxZmE3MDM5MTY2MGUzZV83Njk2NTgxNDA3MjA2_8ac5ea96-8c62-46ed-a72a-16ab2a334425"
      unitRef="usd">400000000</amgn:UpFrontPayment>
    <amgn:RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments
      contextRef="i1dfc25edd9d84950bcbf296614e005a4_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV8xMDg4L2ZyYWc6OGY5MDIzYmQyNTAwNDI0YjhlMWZhNzAzOTE2NjBlM2UvdGV4dHJlZ2lvbjo4ZjkwMjNiZDI1MDA0MjRiOGUxZmE3MDM5MTY2MGUzZV83Njk2NTgxNDA3MjIw_44061ebc-03a8-480a-9e22-dfb02723135d"
      unitRef="usd">850000000</amgn:RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments>
    <us-gaap:InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNDY5NQ_382040d9-5fb7-47c7-9153-03f722213269">Investments&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Available-for-sale investments&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The amortized cost, gross unrealized gains, gross unrealized losses and fair values of interest-bearing securities, which are considered available-for-sale, by type of security were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:1pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:42.174%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.350%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.350%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.350%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.356%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Types of securities as of September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Amortized&lt;br/&gt;cost&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Gross&lt;br/&gt;unrealized&lt;br/&gt;gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Gross&lt;br/&gt;unrealized&lt;br/&gt;losses&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair&lt;br/&gt;values&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;51&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;51&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury bills&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,900&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,900&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Money market mutual funds&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;8,323&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;8,323&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other short-term interest-bearing securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total interest-bearing securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;12,275&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;12,275&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div&gt;&lt;span&gt;&lt;br/&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:42.174%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.350%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.350%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.350%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.356%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Types of securities as of December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Amortized&lt;br/&gt;cost&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Gross&lt;br/&gt;unrealized&lt;br/&gt;gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Gross&lt;br/&gt;unrealized&lt;br/&gt;losses&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair&lt;br/&gt;values&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;129&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;130&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury bills&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,948&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,948&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Money market mutual funds&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,765&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,765&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other short-term interest-bearing securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total interest-bearing securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9,844&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9,845&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The fair values of interest-bearing securities by location in the Condensed Consolidated Balance Sheets were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:64.397%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.423%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated Balance Sheets locations&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cash and cash equivalents&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;11,323&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5,464&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Marketable securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;952&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,381&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total interest-bearing securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;12,275&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9,845&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Cash and cash equivalents in the above table excludes bank account cash of $646 million and $802&#160;million as of September 30, 2021 and December 31, 2020, respectively.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The fair values of available-for-sale investments by contractual maturity were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:64.397%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.423%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Contractual maturities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Maturing in one year or less&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;12,275&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9,795&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Maturing after one year through three years&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;50&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total available-for-sale investments &lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;12,275&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9,845&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;For the three and nine months ended September 30, 2021 and 2020, realized gains and losses on interest-bearing securities were not material. Realized gains and losses on interest-bearing securities are recorded in Other income, net, in the Condensed Consolidated Statements of Income. The cost of securities sold is based on the specific-identification method.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The primary objective of our investment portfolio is to maintain safety of principal, prudent levels of liquidity and acceptable levels of risk. Our investment policy limits interest-bearing security investments to certain types of debt and money market instruments issued by institutions with investment-grade credit ratings, and it places restrictions on maturities and concentration by asset class and issuer. &lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Equity securities&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;We held investments in equity securities with readily determinable fair values (publicly traded securities) of $608 million and $477 million as of September 30, 2021 and December 31, 2020, respectively, which are included in Other noncurrent assets in the Condensed Consolidated Balance Sheets. For the three months ended September 30, 2021 and 2020, net unrealized gains on publicly traded securities were $135&#160;million and $60&#160;million, respectively. For the nine months ended September 30, 2021 and 2020, net unrealized gains on publicly traded securities were $104&#160;million and $65&#160;million, respectively. Realized gains and losses on sales of publicly traded securities for the three and nine months ended September 30, 2021 and 2020 were not material.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;We held investments of $255 million and $203 million in equity securities without readily determinable fair values as of September 30, 2021 and December 31, 2020, respectively, which are included in Other noncurrent assets in the Condensed Consolidated Balance Sheets. For the three months ended September 30, 2021 and 2020, gains due to upward adjustments on these securities were $94&#160;million and $12&#160;million, respectively. For the nine months ended September 30, 2021 and 2020, gains due to upward adjustments on these securities were $129&#160;million and $20&#160;million, respectively. Downward adjustments on these securities were not material. Adjustments were based on observable price transactions.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Equity method investments &lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;BeiGene, Ltd.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;As of September 30, 2021, we had an ownership interest of approximately 20.3% in BeiGene, Ltd. (BeiGene), which is included in Other noncurrent assets in the Condensed Consolidated Balance Sheets and accounted for under the equity method of accounting. We amortize the difference between the fair value of equity securities acquired and our proportionate share of the carrying value of the underlying net assets of BeiGene over the useful lives of the assets that gave rise to this basis difference. This amortization and our share of the results of operations of BeiGene are included in &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Other income, net&lt;/span&gt;&lt;span style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;, in the Condensed Consolidated Statements of Income one quarter in arrears, which began in the second quarter of 2020. &lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;During the three and nine months ended September 30, 2021, the carrying value of our equity investment was adjusted by our share of BeiGene&#x2019;s net loss of $98&#160;million and $181&#160;million, respectively, and amortization of the basis difference of $44&#160;million and $128&#160;million, respectively. During the three and nine months ended September 30, 2021, the carrying value increased by $18&#160;million and $56&#160;million, respectively, from the impact of BeiGene ownership transactions. In addition, during the three and nine months ended September 30, 2021, we increased the carrying value by $50&#160;million as a result of our purchase of additional shares directly from BeiGene. As of September 30, 2021, the carrying value and fair value of our investment in BeiGene totaled $2.7 billion and $6.9 billion, respectively. As of September 30, 2021, we believe the carrying value of our equity investment in BeiGene is fully recoverable.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Neumora Therapeutics, Inc.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt; On September 30, 2021, we acquired approximately 25.9% ownership interest in Neumora Therapeutics, Inc. (Neumora), a privately held company, for $257&#160;million, which is included in Other noncurrent assets in the Condensed Consolidated Balance Sheets, in exchange for a $100&#160;million cash payment and $157&#160;million in noncash consideration primarily related to future services. Although our equity investment provides us with the ability to exercise significant influence over Neumora, we have elected the fair value option to account for our equity investment. Under the fair value option, changes in the fair value of the investment are recognized through earnings each reporting period. We believe the fair value option best reflects the economics of the underlying transaction. &lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Limited partnerships&lt;/span&gt;&lt;/div&gt;&lt;div style="text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;We held limited partnership investments of $556 million and $496 million as of September 30, 2021 and December 31, 2020, respectively, which are included in Other noncurrent assets in the Condensed Consolidated Balance Sheets. These investments, primarily investment funds of early-stage biotechnology companies, are accounted for by using the equity method of accounting and are measured by using our proportionate share of the net asset values of the underlying investments held by the limited partnerships as a practical expedient. These investments are typically redeemable only through distributions upon liquidation of the underlying assets. As of September 30, 2021, unfunded additional commitments to be made for these investments during the next several years were not material. For the three months ended September 30, 2021 and 2020, net unrealized gains and losses on our limited partnership investments were a net loss of $43&#160;million and a net gain of $63&#160;million, respectively. For the nine months ended September 30, 2021 and 2020, net unrealized gains from our limited partnership investments were $122&#160;million and $73&#160;million, respectively.&lt;/span&gt;&lt;/div&gt;</us-gaap:InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock>
    <us-gaap:DebtSecuritiesAvailableForSaleTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNDc0MA_d807850d-f0b6-4038-bb00-ebf94d23945e">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The amortized cost, gross unrealized gains, gross unrealized losses and fair values of interest-bearing securities, which are considered available-for-sale, by type of security were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:1pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:42.174%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.350%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.350%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.350%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.356%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Types of securities as of September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Amortized&lt;br/&gt;cost&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Gross&lt;br/&gt;unrealized&lt;br/&gt;gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Gross&lt;br/&gt;unrealized&lt;br/&gt;losses&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair&lt;br/&gt;values&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;51&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;51&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury bills&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,900&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,900&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Money market mutual funds&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;8,323&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;8,323&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other short-term interest-bearing securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total interest-bearing securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;12,275&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;12,275&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div&gt;&lt;span&gt;&lt;br/&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:42.174%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.350%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.350%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.350%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.356%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Types of securities as of December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Amortized&lt;br/&gt;cost&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Gross&lt;br/&gt;unrealized&lt;br/&gt;gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Gross&lt;br/&gt;unrealized&lt;br/&gt;losses&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair&lt;br/&gt;values&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;129&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;130&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury bills&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,948&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,948&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Money market mutual funds&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,765&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,765&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other short-term interest-bearing securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total interest-bearing securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9,844&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9,845&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</us-gaap:DebtSecuritiesAvailableForSaleTableTextBlock>
    <us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis
      contextRef="i0523566bb4bd4ac7a167861d41b07412_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMS0yLTEtMS0w_7b0fc87c-cfff-464b-afd9-7bdc622f8de9"
      unitRef="usd">51000000</us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
      contextRef="i0523566bb4bd4ac7a167861d41b07412_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMS00LTEtMS0w_3b258ead-7562-4417-8b7a-62071e24e378"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
      contextRef="i0523566bb4bd4ac7a167861d41b07412_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMS02LTEtMS0w_177ed699-3cc2-4b97-9151-a7a7b2a871f4"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i0523566bb4bd4ac7a167861d41b07412_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMS04LTEtMS0w_17c0bbc2-e3ba-43fc-8ff5-db8cd27ec069"
      unitRef="usd">51000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis
      contextRef="i8db023e72bf0457098764c83dfe06255_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMi0yLTEtMS0w_cb30ac17-49ef-41c8-bc77-d9a877ab8664"
      unitRef="usd">3900000000</us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
      contextRef="i8db023e72bf0457098764c83dfe06255_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMi00LTEtMS0w_fd467c46-c02d-48ae-87e1-b1fb3bd7b63b"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
      contextRef="i8db023e72bf0457098764c83dfe06255_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMi02LTEtMS0w_f8c34fb0-81c7-4045-9d69-df5d6a5949d7"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i8db023e72bf0457098764c83dfe06255_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMi04LTEtMS0w_5e740994-1b85-439b-8f1c-ea290c7dfd02"
      unitRef="usd">3900000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis
      contextRef="i3022e170e868460588b8873ad8b918de_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTItMi0xLTEtMA_c2e011ab-f19f-4bc4-a6d7-4918e68681ec"
      unitRef="usd">8323000000</us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
      contextRef="i3022e170e868460588b8873ad8b918de_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTItNC0xLTEtMA_f6b7a9b8-9067-4650-a445-165de43c2156"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
      contextRef="i3022e170e868460588b8873ad8b918de_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTItNi0xLTEtMA_6ad8effe-96ec-4b27-add2-c8b30964d721"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i3022e170e868460588b8873ad8b918de_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTItOC0xLTEtMA_6f86a523-42eb-4e81-a66f-d4d978051383"
      unitRef="usd">8323000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis
      contextRef="ic7d3b5bd8e574e95949520f4cff15af1_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTMtMi0xLTEtMA_baf0a0dc-2b07-4046-ada5-c5d2614072a7"
      unitRef="usd">1000000</us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
      contextRef="ic7d3b5bd8e574e95949520f4cff15af1_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTMtNC0xLTEtMA_e6d7686d-4b47-464b-916e-dcdf30675cf5"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
      contextRef="ic7d3b5bd8e574e95949520f4cff15af1_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTMtNi0xLTEtMA_e84df3c2-f5b8-480c-8723-a5e9d54a3f2b"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="ic7d3b5bd8e574e95949520f4cff15af1_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTMtOC0xLTEtMA_a2887273-b074-48a4-a0de-d7f88ac583ab"
      unitRef="usd">1000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTYtMi0xLTEtMA_c2ac0ba4-d62b-40d7-a486-9d95188417ee"
      unitRef="usd">12275000000</us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTYtNC0xLTEtMA_5cba5501-c49f-4214-b611-c88e190f4e0c"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTYtNi0xLTEtMA_691bfb98-5a11-46e5-99a5-e6dc6f16079f"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjA4OGY1Njc2ZmQ5YjRhMTY5NWFjZmZkYzIxNGY0ZWUyL3RhYmxlcmFuZ2U6MDg4ZjU2NzZmZDliNGExNjk1YWNmZmRjMjE0ZjRlZTJfMTYtOC0xLTEtMA_803a0be5-b278-4d56-bca1-fc3793897cb2"
      unitRef="usd">12275000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis
      contextRef="i507488fbf87d4c6296eb13e3e0006fbf_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMS0yLTEtMS0w_b073ae35-8215-4e16-868f-dc0ab8e62044"
      unitRef="usd">129000000</us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
      contextRef="i507488fbf87d4c6296eb13e3e0006fbf_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMS00LTEtMS0w_2f3a8107-4b10-42bc-93f7-588ef43562c3"
      unitRef="usd">1000000</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
      contextRef="i507488fbf87d4c6296eb13e3e0006fbf_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMS02LTEtMS0w_ec1b261e-c11a-43a0-a498-c046ad0fda54"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i507488fbf87d4c6296eb13e3e0006fbf_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMS04LTEtMS0w_821c9976-2b6a-489d-a07c-4b9cfee84192"
      unitRef="usd">130000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis
      contextRef="i8ba30f0c09fc4bfd9fe36a47079d2854_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMi0yLTEtMS0w_97c901c1-2670-465a-9637-c30c6456e7e7"
      unitRef="usd">4948000000</us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
      contextRef="i8ba30f0c09fc4bfd9fe36a47079d2854_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMi00LTEtMS0w_47a979ee-0eeb-4bf8-bfbe-cc0bbd08057a"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
      contextRef="i8ba30f0c09fc4bfd9fe36a47079d2854_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMi02LTEtMS0w_05a49f0d-ebab-402b-92e9-d78d9de0bf02"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i8ba30f0c09fc4bfd9fe36a47079d2854_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMi04LTEtMS0w_3ab40ab0-f380-433e-adba-cd1731f50414"
      unitRef="usd">4948000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis
      contextRef="i54f838959ac943e79d09dcf9e6faada4_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTItMi0xLTEtMA_a1ea0363-8b4b-4fe8-9b00-734896df6c49"
      unitRef="usd">4765000000</us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
      contextRef="i54f838959ac943e79d09dcf9e6faada4_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTItNC0xLTEtMA_ea07f742-3a42-43e8-8076-46991b766b67"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
      contextRef="i54f838959ac943e79d09dcf9e6faada4_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTItNi0xLTEtMA_88ceae73-b76c-49d4-8658-bab9efa3fd43"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i54f838959ac943e79d09dcf9e6faada4_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTItOC0xLTEtMA_52e58e2a-858d-44f7-9d72-fcf6545f4169"
      unitRef="usd">4765000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis
      contextRef="i84edbdc908bc4493a769cf963ac32f28_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTMtMi0xLTEtMA_feb3b98c-84f0-4040-82fa-f2bda0660dda"
      unitRef="usd">2000000</us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
      contextRef="i84edbdc908bc4493a769cf963ac32f28_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTMtNC0xLTEtMA_dce2acfe-619f-4371-a5dc-f2b7adee31ed"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
      contextRef="i84edbdc908bc4493a769cf963ac32f28_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTMtNi0xLTEtMA_3b701d2a-b586-4162-acd6-7eda21a99452"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i84edbdc908bc4493a769cf963ac32f28_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTMtOC0xLTEtMA_b458b5f4-6da7-4186-94c9-4982908fb40f"
      unitRef="usd">2000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTQtMi0xLTEtMA_de87e067-e85e-42de-9309-ebac2da99dff"
      unitRef="usd">9844000000</us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTQtNC0xLTEtMA_9d39308f-b619-495c-9c8a-269369c78c17"
      unitRef="usd">1000000</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax>
    <us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTQtNi0xLTEtMA_0e29cb00-59d6-44c6-a8e2-e2705894efd4"
      unitRef="usd">0</us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOjZiN2Q0ZWIyMmY2MzQ4YzliOTY4ZWE5OGFjNjY1MDJjL3RhYmxlcmFuZ2U6NmI3ZDRlYjIyZjYzNDhjOWI5NjhlYTk4YWM2NjUwMmNfMTQtOC0xLTEtMA_52474026-260e-4659-987c-6febf6db20c2"
      unitRef="usd">9845000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <amgn:FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNDc1Nw_1a4c348a-d27a-401e-b876-83d4882296de">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The fair values of interest-bearing securities by location in the Condensed Consolidated Balance Sheets were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:64.397%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.423%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated Balance Sheets locations&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cash and cash equivalents&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;11,323&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5,464&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Marketable securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;952&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,381&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total interest-bearing securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;12,275&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9,845&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</amgn:FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock>
    <us-gaap:CashAndCashEquivalentsFairValueDisclosure
      contextRef="i6a8d71c465184aa38c33193a90315560_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmY5M2FhZWEyNzZmNDRiMGJhMTUzZTE2NTYzYTM5OGEzL3RhYmxlcmFuZ2U6ZjkzYWFlYTI3NmY0NGIwYmExNTNlMTY1NjNhMzk4YTNfMS0yLTEtMS0w_b77aa85a-efac-467b-871a-4b4696e3529b"
      unitRef="usd">11323000000</us-gaap:CashAndCashEquivalentsFairValueDisclosure>
    <us-gaap:CashAndCashEquivalentsFairValueDisclosure
      contextRef="if5d779b254da4c18b8454e5bf7051777_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmY5M2FhZWEyNzZmNDRiMGJhMTUzZTE2NTYzYTM5OGEzL3RhYmxlcmFuZ2U6ZjkzYWFlYTI3NmY0NGIwYmExNTNlMTY1NjNhMzk4YTNfMS00LTEtMS0w_75ac1cf6-465d-4dde-8d4e-ac1a37b05270"
      unitRef="usd">5464000000</us-gaap:CashAndCashEquivalentsFairValueDisclosure>
    <us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent
      contextRef="i6a8d71c465184aa38c33193a90315560_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmY5M2FhZWEyNzZmNDRiMGJhMTUzZTE2NTYzYTM5OGEzL3RhYmxlcmFuZ2U6ZjkzYWFlYTI3NmY0NGIwYmExNTNlMTY1NjNhMzk4YTNfMi0yLTEtMS0w_249418f4-987a-4ec9-95bb-5885ea7c2ae1"
      unitRef="usd">952000000</us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent>
    <us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent
      contextRef="if5d779b254da4c18b8454e5bf7051777_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmY5M2FhZWEyNzZmNDRiMGJhMTUzZTE2NTYzYTM5OGEzL3RhYmxlcmFuZ2U6ZjkzYWFlYTI3NmY0NGIwYmExNTNlMTY1NjNhMzk4YTNfMi00LTEtMS0w_733acc17-5986-4520-aad0-ee495ff83b67"
      unitRef="usd">4381000000</us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i6a8d71c465184aa38c33193a90315560_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmY5M2FhZWEyNzZmNDRiMGJhMTUzZTE2NTYzYTM5OGEzL3RhYmxlcmFuZ2U6ZjkzYWFlYTI3NmY0NGIwYmExNTNlMTY1NjNhMzk4YTNfMy0yLTEtMS0w_5f453225-9ed7-48c4-843a-67954baa2c04"
      unitRef="usd">12275000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="if5d779b254da4c18b8454e5bf7051777_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmY5M2FhZWEyNzZmNDRiMGJhMTUzZTE2NTYzYTM5OGEzL3RhYmxlcmFuZ2U6ZjkzYWFlYTI3NmY0NGIwYmExNTNlMTY1NjNhMzk4YTNfMy00LTEtMS0w_7c9fbe7f-377b-4e89-9f83-95cbcdc32da5"
      unitRef="usd">9845000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:Cash
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNDcw_f874d811-43b7-432d-bbbf-3903e25680f5"
      unitRef="usd">646000000</us-gaap:Cash>
    <us-gaap:Cash
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNDc3_8dc7b353-8703-4a5d-9c54-8ebaf2585b86"
      unitRef="usd">802000000</us-gaap:Cash>
    <us-gaap:InvestmentsClassifiedByContractualMaturityDateTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNDcwMw_577848ef-d0a8-4182-ab39-26be4fdd1488">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The fair values of available-for-sale investments by contractual maturity were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:64.397%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.423%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Contractual maturities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Maturing in one year or less&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;12,275&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9,795&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Maturing after one year through three years&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;50&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total available-for-sale investments &lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;12,275&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9,845&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</us-gaap:InvestmentsClassifiedByContractualMaturityDateTableTextBlock>
    <us-gaap:AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmJkN2ExNjFmZGE4OTQ4ZGJiN2FhNjhhYThlMjgwODJlL3RhYmxlcmFuZ2U6YmQ3YTE2MWZkYTg5NDhkYmI3YWE2OGFhOGUyODA4MmVfMS0yLTEtMS0w_e3c79901-7b00-4d89-8ace-b053bcefc92f"
      unitRef="usd">12275000000</us-gaap:AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue>
    <us-gaap:AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmJkN2ExNjFmZGE4OTQ4ZGJiN2FhNjhhYThlMjgwODJlL3RhYmxlcmFuZ2U6YmQ3YTE2MWZkYTg5NDhkYmI3YWE2OGFhOGUyODA4MmVfMS00LTEtMS0w_2fe9b5ac-bb85-43b5-b568-2a71cf1339a5"
      unitRef="usd">9795000000</us-gaap:AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue>
    <amgn:AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmJkN2ExNjFmZGE4OTQ4ZGJiN2FhNjhhYThlMjgwODJlL3RhYmxlcmFuZ2U6YmQ3YTE2MWZkYTg5NDhkYmI3YWE2OGFhOGUyODA4MmVfMi0yLTEtMS0w_20f860f8-5d70-44fb-8818-0ddab4737473"
      unitRef="usd">0</amgn:AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue>
    <amgn:AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmJkN2ExNjFmZGE4OTQ4ZGJiN2FhNjhhYThlMjgwODJlL3RhYmxlcmFuZ2U6YmQ3YTE2MWZkYTg5NDhkYmI3YWE2OGFhOGUyODA4MmVfMi00LTEtMS0w_713bb288-3486-4adc-81db-eeb22b882f47"
      unitRef="usd">50000000</amgn:AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmJkN2ExNjFmZGE4OTQ4ZGJiN2FhNjhhYThlMjgwODJlL3RhYmxlcmFuZ2U6YmQ3YTE2MWZkYTg5NDhkYmI3YWE2OGFhOGUyODA4MmVfNy0yLTEtMS0w_62539ff8-409c-4fe0-a1b3-5fc8f5b202d4"
      unitRef="usd">12275000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RhYmxlOmJkN2ExNjFmZGE4OTQ4ZGJiN2FhNjhhYThlMjgwODJlL3RhYmxlcmFuZ2U6YmQ3YTE2MWZkYTg5NDhkYmI3YWE2OGFhOGUyODA4MmVfNy00LTEtMS0w_bb29db13-fc82-4178-b02b-94fa6437403c"
      unitRef="usd">9845000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:EquitySecuritiesFvNi
      contextRef="ib2b89ed4eb094c5f966961837399b7ca_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMTQ4OA_0d7d248b-77f5-4e77-8f6f-a39beaf986c5"
      unitRef="usd">608000000</us-gaap:EquitySecuritiesFvNi>
    <us-gaap:EquitySecuritiesFvNi
      contextRef="ia0271b62203b4afbbefbea6461a32a14_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMTQ5NQ_103cb2b0-529d-475d-acc6-f7e896d6990b"
      unitRef="usd">477000000</us-gaap:EquitySecuritiesFvNi>
    <us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMTcwNA_ce850d56-9a36-4635-a150-418df433efa1"
      unitRef="usd">135000000</us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss>
    <us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMTcxMQ_24842655-9503-4254-85ed-d1d92e53e271"
      unitRef="usd">60000000</us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss>
    <us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMTgzNA_0a6187bd-98f4-4c10-93ca-740a6e79a68d"
      unitRef="usd">104000000</us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss>
    <us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMTg1Mg_8936974f-4a49-4989-8570-ebdd5f8a09c9"
      unitRef="usd">65000000</us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss>
    <us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueAmount
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMjAxMg_02b46afa-f8de-40f1-8c4a-9743720264ac"
      unitRef="usd">255000000</us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueAmount>
    <us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueAmount
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMjAxOQ_26c99ce5-bb58-4006-b0f6-c7590986d338"
      unitRef="usd">203000000</us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueAmount>
    <us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQwNDM4OQ_d428d37c-acfb-4cfe-9e83-204549ad6ea4"
      unitRef="usd">94000000</us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount>
    <us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQwNDQxOQ_90e4e7d4-1a2e-4957-843f-f0f7027cf577"
      unitRef="usd">12000000</us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount>
    <us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfODI0NjMzNzIyODE2OQ_686dea5f-4852-4496-a506-09d9bbe28859"
      unitRef="usd">129000000</us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount>
    <us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQwNDQwNg_de169609-7d2e-4882-a1c4-ea996f5d0703"
      unitRef="usd">20000000</us-gaap:EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount>
    <us-gaap:EquityMethodInvestmentOwnershipPercentage
      contextRef="i88ba0aea99ef48b08518a135f9c253ef_I20210930"
      decimals="3"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfOTg5NTYwNDY2MTA1Mw_344b8f0d-c165-4b9f-bb2f-efbf95ed4046"
      unitRef="number">0.203</us-gaap:EquityMethodInvestmentOwnershipPercentage>
    <us-gaap:IncomeLossFromEquityMethodInvestments
      contextRef="ib7d74024b547459c9c043788d26b2171_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDExOA_e3ef4bb8-8367-4e2e-b7cf-955d293b6eb1"
      unitRef="usd">-98000000</us-gaap:IncomeLossFromEquityMethodInvestments>
    <us-gaap:IncomeLossFromEquityMethodInvestments
      contextRef="i425bed6d2b57481aba5c27ce44f41234_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDEzOA_468ff9c0-ae9e-4ef8-9ead-cf046b8ba39b"
      unitRef="usd">-181000000</us-gaap:IncomeLossFromEquityMethodInvestments>
    <amgn:EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity
      contextRef="ib7d74024b547459c9c043788d26b2171_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDExMA_a51e5bff-aa74-437a-a846-ac35d1922700"
      unitRef="usd">44000000</amgn:EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity>
    <amgn:EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity
      contextRef="i425bed6d2b57481aba5c27ce44f41234_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDExNA_a851498e-4b19-44fb-b599-124e9b040991"
      unitRef="usd">128000000</amgn:EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity>
    <amgn:EquityMethodInvestmentChangeInCarryingValueOther
      contextRef="ib7d74024b547459c9c043788d26b2171_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDEwNg_e63ffbd2-26c0-4b6e-b47a-7fa0bfcbff62"
      unitRef="usd">18000000</amgn:EquityMethodInvestmentChangeInCarryingValueOther>
    <amgn:EquityMethodInvestmentChangeInCarryingValueOther
      contextRef="i425bed6d2b57481aba5c27ce44f41234_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDEwMg_f95213d0-5ac7-4a00-9ab1-844926e90daf"
      unitRef="usd">56000000</amgn:EquityMethodInvestmentChangeInCarryingValueOther>
    <amgn:EquityMethodInvestmentChangeInCarryingValue
      contextRef="ib7d74024b547459c9c043788d26b2171_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDI1Nw_609872ab-128a-4a45-b67e-7b15bb80ed74"
      unitRef="usd">50000000</amgn:EquityMethodInvestmentChangeInCarryingValue>
    <amgn:EquityMethodInvestmentChangeInCarryingValue
      contextRef="i425bed6d2b57481aba5c27ce44f41234_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDI1Nw_de51f072-77e9-4fc0-907a-8b267511d28e"
      unitRef="usd">50000000</amgn:EquityMethodInvestmentChangeInCarryingValue>
    <us-gaap:EquityMethodInvestments
      contextRef="i88ba0aea99ef48b08518a135f9c253ef_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfOTg5NTYwNDY2MjMxNQ_d40d12db-b66c-46d7-b84c-b273509818a1"
      unitRef="usd">2700000000</us-gaap:EquityMethodInvestments>
    <us-gaap:EquityMethodInvestmentQuotedMarketValue
      contextRef="i88ba0aea99ef48b08518a135f9c253ef_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfOTg5NTYwNDY2MjMyNA_4525a57c-7aa8-429a-bb64-5080d087d94d"
      unitRef="usd">6900000000</us-gaap:EquityMethodInvestmentQuotedMarketValue>
    <us-gaap:EquityMethodInvestmentOwnershipPercentage
      contextRef="i14a1d9538f0a492885a9966112c392aa_I20210930"
      decimals="3"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDE4MQ_c9da4339-ca7f-4ce8-a998-c775ea17e5da"
      unitRef="number">0.259</us-gaap:EquityMethodInvestmentOwnershipPercentage>
    <us-gaap:EquityMethodInvestmentAggregateCost
      contextRef="i14a1d9538f0a492885a9966112c392aa_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDE2Ng_55ed510c-915d-4d16-a7a5-b3ddd24ebb25"
      unitRef="usd">257000000</us-gaap:EquityMethodInvestmentAggregateCost>
    <us-gaap:PaymentsToAcquireEquityMethodInvestments
      contextRef="i3c3ace434f6b40b4a14815a09b06178b_D20210930-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDE4NQ_cf26715a-c00d-406c-a599-2f264fee1a4e"
      unitRef="usd">100000000</us-gaap:PaymentsToAcquireEquityMethodInvestments>
    <us-gaap:NoncashOrPartNoncashAcquisitionInvestmentsAcquired1
      contextRef="i3c3ace434f6b40b4a14815a09b06178b_D20210930-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfNzY5NjU4MTQxNDE4OQ_32eaf2b0-92ad-4ec6-b393-a29b891a4bd0"
      unitRef="usd">157000000</us-gaap:NoncashOrPartNoncashAcquisitionInvestmentsAcquired1>
    <us-gaap:AlternativeInvestment
      contextRef="ic38268b0440c4532956b86d64e30b988_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMjQ1OQ_9f024e6f-c6de-43f7-b194-4b7c3f818b22"
      unitRef="usd">556000000</us-gaap:AlternativeInvestment>
    <us-gaap:AlternativeInvestment
      contextRef="i84a786cd4d99438e85fec21c4c798f36_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMjQ2Ng_0ece5f1e-1455-4559-b5cc-1c16ae8b9f71"
      unitRef="usd">496000000</us-gaap:AlternativeInvestment>
    <amgn:AlternativeInvestmentNetGainLoss
      contextRef="i01c954a7c8fa422990f7456e349536ec_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMzIzMg_98de8dec-27a1-4fef-b29f-27f5c251ed2d"
      unitRef="usd">-43000000</amgn:AlternativeInvestmentNetGainLoss>
    <amgn:AlternativeInvestmentNetGainLoss
      contextRef="i9a95e7ba909f487d97ae171134923478_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMzIzOQ_0202569f-f6fe-405d-9b3b-3aab10a9e405"
      unitRef="usd">63000000</amgn:AlternativeInvestmentNetGainLoss>
    <amgn:AlternativeInvestmentNetGainLoss
      contextRef="i2fcb95887a864539b58641131094dfd5_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMzM2MA_b9b3e03e-eea4-427b-98bc-d6c0d7db75b6"
      unitRef="usd">122000000</amgn:AlternativeInvestmentNetGainLoss>
    <amgn:AlternativeInvestmentNetGainLoss
      contextRef="i7d119868ff92459e8484a254322dda06_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV80OS9mcmFnOjUzYjAyMTRhZjZiZDRhMjlhMGM5ZWEyZWE1MmExZGM3L3RleHRyZWdpb246NTNiMDIxNGFmNmJkNGEyOWEwYzllYTJlYTUyYTFkYzdfMzM2Nw_508b7074-848f-492c-bc4e-66da38541110"
      unitRef="usd">73000000</amgn:AlternativeInvestmentNetGainLoss>
    <us-gaap:InventoryDisclosureTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RleHRyZWdpb246MTE2MDZkZTNlYzRmNDgxMDkxZGYxODdlNmE0ODNjZTZfNzM_fea078b8-e46f-41a5-946e-303ddf58671b">Inventories&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Inventories consisted of the following (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:65.128%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.422%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Raw materials&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;667&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;486&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Work in process&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,313&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,437&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Finished goods&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,172&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;970&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt 2px 5.5pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total inventories&lt;/span&gt;&lt;/td&gt;&lt;td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,152&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,893&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</us-gaap:InventoryDisclosureTextBlock>
    <us-gaap:ScheduleOfInventoryCurrentTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RleHRyZWdpb246MTE2MDZkZTNlYzRmNDgxMDkxZGYxODdlNmE0ODNjZTZfNzg_39c79543-bb18-45b3-a21c-4394de6bd61d">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Inventories consisted of the following (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:65.128%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.422%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Raw materials&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;667&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;486&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Work in process&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,313&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,437&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Finished goods&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,172&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;970&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt 2px 5.5pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total inventories&lt;/span&gt;&lt;/td&gt;&lt;td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,152&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,893&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</us-gaap:ScheduleOfInventoryCurrentTableTextBlock>
    <us-gaap:InventoryRawMaterialsNetOfReserves
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfMS0xLTEtMS0w_546bcf9c-de4d-4441-bce8-bc0922d5a7b2"
      unitRef="usd">667000000</us-gaap:InventoryRawMaterialsNetOfReserves>
    <us-gaap:InventoryRawMaterialsNetOfReserves
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfMS0zLTEtMS0w_871c82e9-8ce4-480e-be4b-8b9016d716e0"
      unitRef="usd">486000000</us-gaap:InventoryRawMaterialsNetOfReserves>
    <us-gaap:InventoryWorkInProcessNetOfReserves
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfMi0xLTEtMS0w_1b9b4f84-44a4-4fb3-b9e8-f943e2384229"
      unitRef="usd">2313000000</us-gaap:InventoryWorkInProcessNetOfReserves>
    <us-gaap:InventoryWorkInProcessNetOfReserves
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfMi0zLTEtMS0w_c9279222-0622-4957-89c2-b740dfc34ecb"
      unitRef="usd">2437000000</us-gaap:InventoryWorkInProcessNetOfReserves>
    <us-gaap:InventoryFinishedGoodsNetOfReserves
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfMy0xLTEtMS0w_344c14c4-95aa-4f24-b454-f49872f4be85"
      unitRef="usd">1172000000</us-gaap:InventoryFinishedGoodsNetOfReserves>
    <us-gaap:InventoryFinishedGoodsNetOfReserves
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfMy0zLTEtMS0w_224e2f0f-fd1b-4ba9-b1ee-a2d130672fd8"
      unitRef="usd">970000000</us-gaap:InventoryFinishedGoodsNetOfReserves>
    <us-gaap:InventoryNet
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfNC0xLTEtMS0w_9dcdcbe7-6cce-4c13-b4b6-f0108cf6d308"
      unitRef="usd">4152000000</us-gaap:InventoryNet>
    <us-gaap:InventoryNet
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81Mi9mcmFnOjExNjA2ZGUzZWM0ZjQ4MTA5MWRmMTg3ZTZhNDgzY2U2L3RhYmxlOjNhZjc1N2RiNTI1MTQ0MDRiZjdmZWQzMDY4MmYxODhhL3RhYmxlcmFuZ2U6M2FmNzU3ZGI1MjUxNDQwNGJmN2ZlZDMwNjgyZjE4OGFfNC0zLTEtMS0w_693fe415-5e8b-4cf5-b344-df2b9e5845c4"
      unitRef="usd">3893000000</us-gaap:InventoryNet>
    <us-gaap:GoodwillAndIntangibleAssetsDisclosureTextBlock
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTkxMg_808b001b-8247-446a-8e8e-437babf35dde">Goodwill and other intangible assets&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Goodwill&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The change in the carrying amount of goodwill was as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.707%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:82.331%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.469%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Nine months ended&lt;br/&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Beginning balance&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;14,689&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Currency translation adjustment&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(24)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Ending balance&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;14,665&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="text-align:justify"&gt;&lt;span&gt;&lt;br/&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Other intangible assets&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Other intangible assets consisted of the following (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:32.087%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.426%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.426%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.426%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.426%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.426%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.433%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Gross&lt;br/&gt;carrying&lt;br/&gt;amounts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Accumulated&lt;br/&gt;amortization&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Other intangible&lt;br/&gt;assets, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Gross&lt;br/&gt;carrying&lt;br/&gt;amounts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Accumulated&lt;br/&gt;amortization&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Other intangible&lt;br/&gt;assets, net&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Finite-lived intangible assets:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Developed-product-technology rights&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;25,575&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(12,222)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;13,353&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;25,591&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(10,564)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;15,027&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Licensing rights&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,766&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(2,931)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;835&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,743&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(2,791)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;952&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Marketing-related rights&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,362&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1,099)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;263&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,367&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1,041)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;326&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Research and development technology rights&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,298&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1,120)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;178&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,317&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1,065)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;252&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total finite-lived intangible assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;32,001&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(17,372)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;14,629&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;32,018&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(15,461)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;16,557&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Indefinite-lived intangible assets:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;In-process research and development&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;30&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;30&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;30&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;30&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total other intangible assets&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;32,031&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(17,372)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;14,659&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;32,048&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(15,461)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;16,587&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="text-align:justify;text-indent:22.5pt"&gt;&lt;span&gt;&lt;br/&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Developed-product-technology rights consists of rights related to marketed products. Licensing rights primarily consists of contractual rights to receive future milestone, royalty and profit-sharing payments; capitalized payments to third parties for milestones related to regulatory approvals to commercialize products; and upfront payments associated with royalty obligations for marketed products. Marketing-related rights primarily consists of rights related to the sale and distribution of marketed products. R&amp;amp;D technology rights pertains to technologies used in R&amp;amp;D that have alternative future uses.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;IPR&amp;amp;D consists of R&amp;amp;D projects acquired in a business combination that are not complete at the time of acquisition due to remaining technological risks and/or lack of receipt of required regulatory approvals. We review IPR&amp;amp;D projects for impairment annually, whenever events or changes in circumstances indicate that the carrying amounts may not be recoverable and upon the establishment of technological feasibility or regulatory approval.&lt;/span&gt;&lt;/div&gt;During the three months ended September 30, 2021 and 2020, we recognized amortization associated with our finite-lived intangible assets of $642 million and $708 million, respectively. During the nine months ended September 30, 2021 and 2020, we recognized amortization associated with our finite-lived intangible assets of $1.9 billion and $2.1 billion, respectively. Amortization of intangible assets is primarily included in Cost of sales in the Condensed Consolidated Statements of Income. The total estimated amortization for our finite-lived intangible assets for the remaining three months ending December 31, 2021, and the years ending December 31, 2022, 2023, 2024, 2025 and 2026, are $0.6 billion, $2.5 billion, $2.4 billion, $2.4 billion, $2.2 billion and $1.8 billion, respectively.</us-gaap:GoodwillAndIntangibleAssetsDisclosureTextBlock>
    <us-gaap:ScheduleOfGoodwillTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTkyMw_d1b92ad7-8296-4f5a-ac87-02e7d405444f">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The change in the carrying amount of goodwill was as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.707%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:82.331%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.469%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Nine months ended&lt;br/&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Beginning balance&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;14,689&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Currency translation adjustment&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(24)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Ending balance&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;14,665&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</us-gaap:ScheduleOfGoodwillTextBlock>
    <us-gaap:Goodwill
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOjg4MTE1ZjlhZGI1YjRhOTc5M2Q5M2MzNDcyMzI0OGNiL3RhYmxlcmFuZ2U6ODgxMTVmOWFkYjViNGE5NzkzZDkzYzM0NzIzMjQ4Y2JfMS0xLTEtMS0w_98dc9c75-5136-4638-a98e-f5d18d4c3156"
      unitRef="usd">14689000000</us-gaap:Goodwill>
    <us-gaap:GoodwillForeignCurrencyTranslationGainLoss
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOjg4MTE1ZjlhZGI1YjRhOTc5M2Q5M2MzNDcyMzI0OGNiL3RhYmxlcmFuZ2U6ODgxMTVmOWFkYjViNGE5NzkzZDkzYzM0NzIzMjQ4Y2JfMi0xLTEtMS0w_57dcb140-f536-42a2-93f8-f6e2a6606e02"
      unitRef="usd">-24000000</us-gaap:GoodwillForeignCurrencyTranslationGainLoss>
    <us-gaap:Goodwill
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOjg4MTE1ZjlhZGI1YjRhOTc5M2Q5M2MzNDcyMzI0OGNiL3RhYmxlcmFuZ2U6ODgxMTVmOWFkYjViNGE5NzkzZDkzYzM0NzIzMjQ4Y2JfMy0xLTEtMS0w_1f201e21-631e-49d4-937b-e3fc786fa46f"
      unitRef="usd">14665000000</us-gaap:Goodwill>
    <amgn:ScheduleOfIntangibleAssetsTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTkxMA_47606a9c-5dfe-44db-b916-61f447167900">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Other intangible assets consisted of the following (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:32.087%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.426%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.426%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.426%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.426%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.426%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:9.433%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Gross&lt;br/&gt;carrying&lt;br/&gt;amounts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Accumulated&lt;br/&gt;amortization&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Other intangible&lt;br/&gt;assets, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Gross&lt;br/&gt;carrying&lt;br/&gt;amounts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Accumulated&lt;br/&gt;amortization&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Other intangible&lt;br/&gt;assets, net&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Finite-lived intangible assets:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Developed-product-technology rights&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;25,575&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(12,222)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;13,353&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;25,591&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(10,564)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;15,027&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Licensing rights&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,766&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(2,931)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;835&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,743&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(2,791)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;952&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Marketing-related rights&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,362&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1,099)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;263&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,367&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1,041)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;326&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Research and development technology rights&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,298&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1,120)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;178&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,317&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1,065)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;252&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total finite-lived intangible assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;32,001&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(17,372)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;14,629&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;32,018&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(15,461)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;16,557&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Indefinite-lived intangible assets:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;In-process research and development&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;30&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;30&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;30&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;30&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total other intangible assets&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;32,031&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(17,372)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;14,659&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;32,048&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(15,461)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;16,587&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</amgn:ScheduleOfIntangibleAssetsTableTextBlock>
    <us-gaap:FiniteLivedIntangibleAssetsGross
      contextRef="i9160bae8d5f74cf4a23fbe7ba32fa1b6_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMy0xLTEtMS0w_5ea507ab-dd61-4245-9be8-a6ea0bd1e125"
      unitRef="usd">25575000000</us-gaap:FiniteLivedIntangibleAssetsGross>
    <us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization
      contextRef="i9160bae8d5f74cf4a23fbe7ba32fa1b6_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMy0zLTEtMS0w_f07ca834-6219-4141-89a3-f112fe7d1812"
      unitRef="usd">12222000000</us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization>
    <us-gaap:FiniteLivedIntangibleAssetsNet
      contextRef="i9160bae8d5f74cf4a23fbe7ba32fa1b6_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMy01LTEtMS0w_f2d569c5-75f5-4721-a246-ead4e8f3ca3d"
      unitRef="usd">13353000000</us-gaap:FiniteLivedIntangibleAssetsNet>
    <us-gaap:FiniteLivedIntangibleAssetsGross
      contextRef="ibb2cb97dcaa2448f8abb52ea2809f752_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMy03LTEtMS0w_4a35e7d1-fed5-47c2-8e5e-e0095cd43f47"
      unitRef="usd">25591000000</us-gaap:FiniteLivedIntangibleAssetsGross>
    <us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization
      contextRef="ibb2cb97dcaa2448f8abb52ea2809f752_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMy05LTEtMS0w_c56a132b-56b1-4eac-998d-267fb0b8f168"
      unitRef="usd">10564000000</us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization>
    <us-gaap:FiniteLivedIntangibleAssetsNet
      contextRef="ibb2cb97dcaa2448f8abb52ea2809f752_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMy0xMS0xLTEtMA_25335458-49d0-4cbb-9ac8-96be0dba5a96"
      unitRef="usd">15027000000</us-gaap:FiniteLivedIntangibleAssetsNet>
    <us-gaap:FiniteLivedIntangibleAssetsGross
      contextRef="iccda3c90f3ea4d7ca11b1e7e5979139f_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNC0xLTEtMS0w_fc26d80f-8561-4490-97df-e990b5908c95"
      unitRef="usd">3766000000</us-gaap:FiniteLivedIntangibleAssetsGross>
    <us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization
      contextRef="iccda3c90f3ea4d7ca11b1e7e5979139f_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNC0zLTEtMS0w_86d5fd00-f9ab-472a-aba8-c7ead75472a0"
      unitRef="usd">2931000000</us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization>
    <us-gaap:FiniteLivedIntangibleAssetsNet
      contextRef="iccda3c90f3ea4d7ca11b1e7e5979139f_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNC01LTEtMS0w_62d402cb-549e-4849-b065-88f11dadc035"
      unitRef="usd">835000000</us-gaap:FiniteLivedIntangibleAssetsNet>
    <us-gaap:FiniteLivedIntangibleAssetsGross
      contextRef="i7bfe3a17c67f48848b0a262301253745_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNC03LTEtMS0w_e041a71a-869c-44e8-a639-e92dfac4bc69"
      unitRef="usd">3743000000</us-gaap:FiniteLivedIntangibleAssetsGross>
    <us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization
      contextRef="i7bfe3a17c67f48848b0a262301253745_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNC05LTEtMS0w_ad8b16b9-9787-4ec3-9356-70d520576352"
      unitRef="usd">2791000000</us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization>
    <us-gaap:FiniteLivedIntangibleAssetsNet
      contextRef="i7bfe3a17c67f48848b0a262301253745_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNC0xMS0xLTEtMA_6858b425-1181-4ebd-a779-c87541ee385c"
      unitRef="usd">952000000</us-gaap:FiniteLivedIntangibleAssetsNet>
    <us-gaap:FiniteLivedIntangibleAssetsGross
      contextRef="ie5cd36de21a24c3a974d783bc31683e3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNS0xLTEtMS0w_76f6d887-c7d3-4830-9c87-953e4ec82510"
      unitRef="usd">1362000000</us-gaap:FiniteLivedIntangibleAssetsGross>
    <us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization
      contextRef="ie5cd36de21a24c3a974d783bc31683e3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNS0zLTEtMS0w_bd74c6c5-1015-484a-afd9-0d0a89bdddc2"
      unitRef="usd">1099000000</us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization>
    <us-gaap:FiniteLivedIntangibleAssetsNet
      contextRef="ie5cd36de21a24c3a974d783bc31683e3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNS01LTEtMS0w_0f1f78ce-c837-441f-bebe-ce42b4af4dec"
      unitRef="usd">263000000</us-gaap:FiniteLivedIntangibleAssetsNet>
    <us-gaap:FiniteLivedIntangibleAssetsGross
      contextRef="ifa42c9c20230405db95ebc7c2717a086_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNS03LTEtMS0w_dbf0ca28-6112-4a77-af56-04015d403208"
      unitRef="usd">1367000000</us-gaap:FiniteLivedIntangibleAssetsGross>
    <us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization
      contextRef="ifa42c9c20230405db95ebc7c2717a086_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNS05LTEtMS0w_14c33ecf-3256-4ed4-81dc-6f021c8e0014"
      unitRef="usd">1041000000</us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization>
    <us-gaap:FiniteLivedIntangibleAssetsNet
      contextRef="ifa42c9c20230405db95ebc7c2717a086_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNS0xMS0xLTEtMA_f638f4d9-8aa9-4aa5-aff2-bd8d978cd7c7"
      unitRef="usd">326000000</us-gaap:FiniteLivedIntangibleAssetsNet>
    <us-gaap:FiniteLivedIntangibleAssetsGross
      contextRef="i823fc181443240599bbbbaad667a7fd2_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNi0xLTEtMS0w_eebde804-68d6-4a44-9aa3-30a8a062c174"
      unitRef="usd">1298000000</us-gaap:FiniteLivedIntangibleAssetsGross>
    <us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization
      contextRef="i823fc181443240599bbbbaad667a7fd2_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNi0zLTEtMS0w_046fbaa5-0d51-4001-adfc-a356aa964b19"
      unitRef="usd">1120000000</us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization>
    <us-gaap:FiniteLivedIntangibleAssetsNet
      contextRef="i823fc181443240599bbbbaad667a7fd2_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNi01LTEtMS0w_dda279aa-f29c-4150-882d-4171d685a661"
      unitRef="usd">178000000</us-gaap:FiniteLivedIntangibleAssetsNet>
    <us-gaap:FiniteLivedIntangibleAssetsGross
      contextRef="i3c93fbbb176e41ab97226ab5c020020d_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNi03LTEtMS0w_926d028b-916f-47d0-9bee-8a8ef8778724"
      unitRef="usd">1317000000</us-gaap:FiniteLivedIntangibleAssetsGross>
    <us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization
      contextRef="i3c93fbbb176e41ab97226ab5c020020d_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNi05LTEtMS0w_c42fadc3-407c-4dcc-9950-8cb4363eb72d"
      unitRef="usd">1065000000</us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization>
    <us-gaap:FiniteLivedIntangibleAssetsNet
      contextRef="i3c93fbbb176e41ab97226ab5c020020d_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNi0xMS0xLTEtMA_eafb08ad-ed19-4e97-b1f6-9be52ee985ed"
      unitRef="usd">252000000</us-gaap:FiniteLivedIntangibleAssetsNet>
    <us-gaap:FiniteLivedIntangibleAssetsGross
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNy0xLTEtMS0w_62f2de0e-536a-4bb9-b2a6-4969afb81554"
      unitRef="usd">32001000000</us-gaap:FiniteLivedIntangibleAssetsGross>
    <us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNy0zLTEtMS0w_161717a6-9bf8-431f-85ac-41ccfcb2ece2"
      unitRef="usd">17372000000</us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization>
    <us-gaap:FiniteLivedIntangibleAssetsNet
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNy01LTEtMS0w_9dba70a2-3a06-425a-b893-3913695d18a5"
      unitRef="usd">14629000000</us-gaap:FiniteLivedIntangibleAssetsNet>
    <us-gaap:FiniteLivedIntangibleAssetsGross
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNy03LTEtMS0w_8989105d-7e9d-4d5e-8aa4-cc78847746fe"
      unitRef="usd">32018000000</us-gaap:FiniteLivedIntangibleAssetsGross>
    <us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNy05LTEtMS0w_c7225c5a-0950-468f-8335-3d34718e5401"
      unitRef="usd">15461000000</us-gaap:FiniteLivedIntangibleAssetsAccumulatedAmortization>
    <us-gaap:FiniteLivedIntangibleAssetsNet
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfNy0xMS0xLTEtMA_d49bcf7d-a83a-4fc8-a8a0-5aecb1f953a6"
      unitRef="usd">16557000000</us-gaap:FiniteLivedIntangibleAssetsNet>
    <us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill
      contextRef="i62a4ce9947344dd28aeec0db74164aef_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfOS0xLTEtMS0w_cc839bf2-6537-4985-8f52-18532c1f9eed"
      unitRef="usd">30000000</us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill>
    <us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill
      contextRef="i62a4ce9947344dd28aeec0db74164aef_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfOS01LTEtMS0w_35e3a7ba-5ece-4e49-a081-06f47137a8cb"
      unitRef="usd">30000000</us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill>
    <us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill
      contextRef="i858e9c4fb9dc48f1b8c2568fc92c7dfd_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfOS03LTEtMS0w_b95d4f71-6937-480b-bc0f-bb79720315ec"
      unitRef="usd">30000000</us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill>
    <us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill
      contextRef="i858e9c4fb9dc48f1b8c2568fc92c7dfd_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfOS0xMS0xLTEtMA_3fe66bff-fa9d-47b1-856c-6bb61698f3d8"
      unitRef="usd">30000000</us-gaap:IndefiniteLivedIntangibleAssetsExcludingGoodwill>
    <amgn:IdentifiableIntangibleAssetsGross
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMTAtMS0xLTEtMA_f111a8ec-9c9a-472d-abe0-d2de0e5d6a42"
      unitRef="usd">32031000000</amgn:IdentifiableIntangibleAssetsGross>
    <amgn:IdentifiableIntangibleAssetsAccumulatedAmortization
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMTAtMy0xLTEtMA_303f10e1-ceaa-4a99-885a-b0acb7fa3ddc"
      unitRef="usd">17372000000</amgn:IdentifiableIntangibleAssetsAccumulatedAmortization>
    <us-gaap:IntangibleAssetsNetExcludingGoodwill
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMTAtNS0xLTEtMA_5ad73002-69a6-42dd-af33-2f52964b0961"
      unitRef="usd">14659000000</us-gaap:IntangibleAssetsNetExcludingGoodwill>
    <amgn:IdentifiableIntangibleAssetsGross
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMTAtNy0xLTEtMA_09086fd0-eaca-4c15-ac81-9068fbf27d36"
      unitRef="usd">32048000000</amgn:IdentifiableIntangibleAssetsGross>
    <amgn:IdentifiableIntangibleAssetsAccumulatedAmortization
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMTAtOS0xLTEtMA_825c73bb-c6d3-4392-828c-7e9587f06747"
      unitRef="usd">15461000000</amgn:IdentifiableIntangibleAssetsAccumulatedAmortization>
    <us-gaap:IntangibleAssetsNetExcludingGoodwill
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RhYmxlOmE2NzNmZTU1MGQzYzQ1ZjY5ZjJkNjBlODBiNjU0NTFlL3RhYmxlcmFuZ2U6YTY3M2ZlNTUwZDNjNDVmNjlmMmQ2MGU4MGI2NTQ1MWVfMTAtMTEtMS0xLTA_e48c27b7-7990-4794-bfbd-266e64fd46b9"
      unitRef="usd">16587000000</us-gaap:IntangibleAssetsNetExcludingGoodwill>
    <us-gaap:AmortizationOfIntangibleAssets
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTM5NA_8fdeada9-457a-46fe-ba87-12543bef952b"
      unitRef="usd">642000000</us-gaap:AmortizationOfIntangibleAssets>
    <us-gaap:AmortizationOfIntangibleAssets
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTQwMQ_7819d21d-ff0d-42d5-9bcc-0a5ffc419f73"
      unitRef="usd">708000000</us-gaap:AmortizationOfIntangibleAssets>
    <us-gaap:AmortizationOfIntangibleAssets
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTUzOQ_1e8aba80-5476-420c-a102-cf253040d380"
      unitRef="usd">1900000000</us-gaap:AmortizationOfIntangibleAssets>
    <us-gaap:AmortizationOfIntangibleAssets
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTU0Ng_1743b5e2-28dc-4286-816d-d4678cb2f12e"
      unitRef="usd">2100000000</us-gaap:AmortizationOfIntangibleAssets>
    <us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTg2MQ_cdd99e9a-8eb8-40b2-bf42-9cbee61d5a00"
      unitRef="usd">600000000</us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear>
    <us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTg2NQ_82f691c2-5080-477f-8758-33673989a9e0"
      unitRef="usd">2500000000</us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths>
    <us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTg2OQ_8dc92e32-a0de-4c77-a6bb-e4acfcf1e5f1"
      unitRef="usd">2400000000</us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo>
    <us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearThree
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTg3Mw_658ad877-a41d-4c55-a7a8-684a832596a4"
      unitRef="usd">2400000000</us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearThree>
    <us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFour
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTg3Nw_42a2b487-16ae-4694-8ee1-27b47f088b8d"
      unitRef="usd">2200000000</us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFour>
    <us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFive
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81NS9mcmFnOjIzN2M3YWFkNzcyZTQ1OGU4ZGQ4ZTIyNDMwNTljOWYxL3RleHRyZWdpb246MjM3YzdhYWQ3NzJlNDU4ZThkZDhlMjI0MzA1OWM5ZjFfMTg4NA_67ad68ae-7036-46c0-9053-ed819513baa9"
      unitRef="usd">1800000000</us-gaap:FiniteLivedIntangibleAssetsAmortizationExpenseYearFive>
    <us-gaap:DebtDisclosureTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNzY2_68b740c1-43e6-486d-96b0-df99b867bee7">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Our borrowings consisted of the following (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:65.128%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.422%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1.25% &#x20ac;1,250 million notes due 2022 (1.25% 2022 euro Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,448&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,527&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.70% notes due 2022 (2.70% 2022 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;500&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;500&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.65% notes due 2022 (2.65% 2022 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,500&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,500&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.625% notes due 2022 (3.625% 2022 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;750&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;750&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;0.41% CHF700 million bonds due 2023 (0.41% 2023 Swiss franc Bonds)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;751&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;791&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.25% notes due 2023 (2.25% 2023 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;750&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;750&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.625% notes due 2024 (3.625% 2024 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,400&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,400&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1.90% notes due 2025 (1.90% 2025 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;500&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;500&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.125% notes due 2025 (3.125% 2025 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,000&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,000&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.00% &#x20ac;750 million notes due 2026 (2.00% 2026 euro Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;869&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;916&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.60% notes due 2026 (2.60% 2026 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5.50% &#xa3;475 million notes due 2026 (5.50% 2026 pound sterling Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;640&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;649&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.20% notes due 2027 (2.20% 2027 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,750&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,750&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.20% notes due 2027 (3.20% 2027 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,000&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,000&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1.65% note due 2028 (1.65% 2028 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.00% &#xa3;700 million notes due 2029 (4.00% 2029 pound sterling Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;943&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;957&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.45% notes due 2030 (2.45% 2030 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.30% notes due 2031 (2.30% 2031 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.00% notes due 2032 (2.00% 2032 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6.375% notes due 2037 (6.375% 2037 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;478&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;478&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6.90% notes due 2038 (6.90% 2038 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;254&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;254&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6.40% notes due 2039 (6.40% 2039 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;333&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;333&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.15% notes due 2040 (3.15% 2040 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,000&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,000&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5.75% notes due 2040 (5.75% 2040 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;373&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;373&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.80% note due 2041 (2.80% 2041 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,150&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.95% notes due 2041 (4.95% 2041 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;600&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;600&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5.15% notes due 2041 (5.15% 2041 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;729&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;729&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5.65% notes due 2042 (5.65% 2042 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;415&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;415&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5.375% notes due 2043 (5.375% 2043 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;185&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;185&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.40% notes due 2045 (4.40% 2045 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.563% notes due 2048 (4.563% 2048 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,415&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,415&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.375% notes due 2050 (3.375% 2050 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.663% notes due 2051 (4.663% 2051 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,541&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,541&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.00% notes due 2052 (3.00% 2052 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,350&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.77% notes due 2053 (2.77% 2053 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;940&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;940&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other notes due 2097&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;100&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;100&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Unamortized bond discounts, premiums and issuance costs, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1,221)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1,188)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Fair value adjustments&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;371&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;566&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;15&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total carrying value of debt&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;37,579&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;32,986&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Less current portion&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(4,288)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(91)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total long-term debt&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;33,291&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;32,895&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;There are no material differences between the effective interest rates and coupon rates of any of our borrowings, except for the 4.563% 2048 Notes, the 4.663% 2051 Notes and the 2.77% 2053 Notes, which have effective interest rates of 6.3%, 5.6% and 5.2%, respectively.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;During the three months ended September 30, 2021, we issued $5.0&#160;billion of debt consisting of $1.25&#160;billion of the 1.65% 2028 Notes, $1.25&#160;billion of the 2.00% 2032 Notes, $1.15&#160;billion of the 2.80% 2041 Notes and $1.35&#160;billion of the 3.00% 2052 Notes. In the event of a change-in-control triggering event, as defined in the terms of the notes, we may be required to purchase all or a portion of these notes at a price equal to 101% of the principal amount of the notes plus accrued and unpaid interest. In addition, these notes may be redeemed at any time at our option, in whole or in part, at the principal amount of the notes being redeemed plus accrued and unpaid interest and a make-whole amount, which are defined by the terms of the notes. The notes may be redeemed without payment of make-whole amounts if redemption occurs during a specified period of time immediately prior to the maturing of the notes. Such time periods range from two months to six months prior to maturity.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;During the three months ended June 30, 2021, we entered into the following interest rate swap contracts: (i) $1.0&#160;billion notional amount with respect to the 2.45% 2030 Notes, resulting in an effective interest rate of three-month LIBOR plus 1.0% for that portion of the notes, and (ii) $500&#160;million notional amount with respect to the 2.30% 2031 Notes, resulting in an effective interest rate of three-month LIBOR plus 0.8% for that portion of the notes.&lt;/span&gt;&lt;/div&gt;</us-gaap:DebtDisclosureTextBlock>
    <us-gaap:ScheduleOfDebtInstrumentsTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNzU5_7f3972f8-33f4-45dc-a2d8-d4e92ab8076b">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Our borrowings consisted of the following (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:65.128%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.422%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1.25% &#x20ac;1,250 million notes due 2022 (1.25% 2022 euro Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,448&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,527&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.70% notes due 2022 (2.70% 2022 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;500&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;500&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.65% notes due 2022 (2.65% 2022 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,500&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,500&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.625% notes due 2022 (3.625% 2022 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;750&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;750&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;0.41% CHF700 million bonds due 2023 (0.41% 2023 Swiss franc Bonds)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;751&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;791&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.25% notes due 2023 (2.25% 2023 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;750&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;750&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.625% notes due 2024 (3.625% 2024 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,400&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,400&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1.90% notes due 2025 (1.90% 2025 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;500&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;500&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.125% notes due 2025 (3.125% 2025 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,000&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,000&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.00% &#x20ac;750 million notes due 2026 (2.00% 2026 euro Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;869&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;916&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.60% notes due 2026 (2.60% 2026 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5.50% &#xa3;475 million notes due 2026 (5.50% 2026 pound sterling Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;640&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;649&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.20% notes due 2027 (2.20% 2027 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,750&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,750&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.20% notes due 2027 (3.20% 2027 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,000&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,000&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1.65% note due 2028 (1.65% 2028 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.00% &#xa3;700 million notes due 2029 (4.00% 2029 pound sterling Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;943&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;957&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.45% notes due 2030 (2.45% 2030 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.30% notes due 2031 (2.30% 2031 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.00% notes due 2032 (2.00% 2032 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6.375% notes due 2037 (6.375% 2037 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;478&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;478&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6.90% notes due 2038 (6.90% 2038 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;254&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;254&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6.40% notes due 2039 (6.40% 2039 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;333&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;333&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.15% notes due 2040 (3.15% 2040 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,000&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,000&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5.75% notes due 2040 (5.75% 2040 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;373&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;373&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.80% note due 2041 (2.80% 2041 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,150&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.95% notes due 2041 (4.95% 2041 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;600&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;600&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5.15% notes due 2041 (5.15% 2041 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;729&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;729&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5.65% notes due 2042 (5.65% 2042 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;415&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;415&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5.375% notes due 2043 (5.375% 2043 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;185&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;185&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.40% notes due 2045 (4.40% 2045 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.563% notes due 2048 (4.563% 2048 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,415&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,415&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.375% notes due 2050 (3.375% 2050 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.663% notes due 2051 (4.663% 2051 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,541&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,541&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.00% notes due 2052 (3.00% 2052 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,350&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.77% notes due 2053 (2.77% 2053 Notes)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;940&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;940&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other notes due 2097&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;100&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;100&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Unamortized bond discounts, premiums and issuance costs, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1,221)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1,188)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Fair value adjustments&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;371&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;566&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;15&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total carrying value of debt&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;37,579&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;32,986&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Less current portion&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(4,288)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(91)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total long-term debt&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;33,291&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;32,895&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</us-gaap:ScheduleOfDebtInstrumentsTextBlock>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i28a3a2e4d2f24ec1ab05429cee726f75_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMS0wLTEtMS0wL3RleHRyZWdpb246ZTlmMDViZTgxYjQwNGQ5MjlhNzE1NjQ4MWFmY2E1YmVfNA_f963eee7-74ee-4477-958e-7a5ca5e071f0"
      unitRef="number">0.0125</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentFaceAmount
      contextRef="i28a3a2e4d2f24ec1ab05429cee726f75_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMS0wLTEtMS0wL3RleHRyZWdpb246ZTlmMDViZTgxYjQwNGQ5MjlhNzE1NjQ4MWFmY2E1YmVfNw_1dc731b6-e1a1-4045-8da9-68b986f48726"
      unitRef="eur">1250000000</us-gaap:DebtInstrumentFaceAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i28a3a2e4d2f24ec1ab05429cee726f75_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMS0xLTEtMS0w_796a708e-3103-4188-a6df-f71ab366bf92"
      unitRef="usd">1448000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i1d8b35fb400b4d018ac1fc3ac92c4e11_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMS0zLTEtMS0w_406b4953-5e29-44e2-baf3-52b5d9cefe28"
      unitRef="usd">1527000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="iba85a821e6d84b96a52fc42ef1b75604_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMi0wLTEtMS0wL3RleHRyZWdpb246MjBkZmZiZGFkYWE5NDJhMzhiYWNkNTYwZTViM2I1MzhfNA_a5bd67ab-1858-4ba4-8bf2-83e86a3fd1fc"
      unitRef="number">0.0270</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="iba85a821e6d84b96a52fc42ef1b75604_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMi0xLTEtMS0w_5283a12e-da3d-448a-a54b-dcca3c519cf1"
      unitRef="usd">500000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ia88d5a3b1b5c414db7ff8890b7c96f91_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMi0zLTEtMS0w_e3772fef-1987-4703-b07e-c713feedc9eb"
      unitRef="usd">500000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i1a04775f93b24e3c83787a805db33fd7_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMy0wLTEtMS0wL3RleHRyZWdpb246MWU3ZmQwMzZiMGM2NGI4Y2EyMmRmZmM5ZDQzZGY3ZDBfNA_aca13ab5-2234-4a19-9cde-827a25c90bc1"
      unitRef="number">0.0265</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i1a04775f93b24e3c83787a805db33fd7_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMy0xLTEtMS0w_0f0857dd-5e77-4d91-81f5-cabd07f5d572"
      unitRef="usd">1500000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i071cb4027c8549148b8bd96aea3e7c5c_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMy0zLTEtMS0w_070779e2-fb4d-4170-bd9c-0b9e504c36d1"
      unitRef="usd">1500000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="ib744f296eafb4f8d88d2a38efb8a48a3_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNC0wLTEtMS0wL3RleHRyZWdpb246NTI2N2Q5NmUwZDEwNGEwZWEwYzgyODc1ZjVmMWNiZGVfNA_bdf1eaf9-2d91-486f-a028-f01c3f191771"
      unitRef="number">0.03625</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ib744f296eafb4f8d88d2a38efb8a48a3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNC0xLTEtMS0w_1834e7b9-e9a5-4f80-9ed1-f174d4bf1217"
      unitRef="usd">750000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ie50a52f9a64743be865aca69358499b2_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNC0zLTEtMS0w_5e1d6f1c-a22b-4e2c-908e-8c94a99bbcfd"
      unitRef="usd">750000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="id0d88ff8ca444d28a9d31155d2af6123_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNS0wLTEtMS0wL3RleHRyZWdpb246Nzc5MDUyOTE4NjRhNGNhYmFiZDgyNjM5OTRjN2I4NjVfNA_9759bd28-d6b1-442f-9601-e4c0dac5ac67"
      unitRef="number">0.0041</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentFaceAmount
      contextRef="id0d88ff8ca444d28a9d31155d2af6123_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNS0wLTEtMS0wL3RleHRyZWdpb246Nzc5MDUyOTE4NjRhNGNhYmFiZDgyNjM5OTRjN2I4NjVfNw_1c72fcf6-91c5-4ccb-bf1b-44bdb9dc8e20"
      unitRef="chf">700000000</us-gaap:DebtInstrumentFaceAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="id0d88ff8ca444d28a9d31155d2af6123_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNS0xLTEtMS0w_b73fc250-973f-4f2a-97b3-417df60e425d"
      unitRef="usd">751000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="iaccb7326e7d146e0aafad220d316b604_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNS0zLTEtMS0w_d069955f-193e-42db-a82f-bf1ab8309f21"
      unitRef="usd">791000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="id7b48ebaee8d4fddada565c9d549a4af_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNi0wLTEtMS0wL3RleHRyZWdpb246MmNiZTQxOGRjYTIxNGNlNDk1N2NjZGJjZDNkNzE4ZmNfNA_6343e35a-09e9-4cb0-9267-cd15d7075e17"
      unitRef="number">0.0225</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="id7b48ebaee8d4fddada565c9d549a4af_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNi0xLTEtMS0w_edb10973-533d-4a23-893e-6efa8d5ab021"
      unitRef="usd">750000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="id1e3e3f0ae1a4a3fb3b7e07bf050efd6_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNi0zLTEtMS0w_a2cdd1b3-5b05-4c0e-8bcb-4dd4aba0d90b"
      unitRef="usd">750000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i14cb17bbd31f41deb2c7c3feb4b40b34_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNy0wLTEtMS0wL3RleHRyZWdpb246NjE0NzdkNmZkN2M2NGY1YjlhZDhhN2FmODNhYTE1MGFfNA_e690b70a-99a4-4c23-8bfb-a844c444b26b"
      unitRef="number">0.03625</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i14cb17bbd31f41deb2c7c3feb4b40b34_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNy0xLTEtMS0w_90d72ab5-b3cc-4e39-988b-37b19f9a3b1b"
      unitRef="usd">1400000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i3f99f7b28ace4d3b80f5f9385a149eaf_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfNy0zLTEtMS0w_1a9d2120-5769-4fee-9f6f-2fea0062f052"
      unitRef="usd">1400000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i3e1c0c3571924fcf9795dd47036e02c4_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfOC0wLTEtMS0wL3RleHRyZWdpb246ZDVmNWI5ZDllOWU4NDQyMDhjZDBkZTBhNGU1ZTY1M2NfNA_df7845b6-b6ba-4339-a10e-c5bf11c05fbc"
      unitRef="number">0.0190</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i3e1c0c3571924fcf9795dd47036e02c4_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfOC0xLTEtMS0w_dca8f5ac-59da-4b16-9799-5af92d282eb5"
      unitRef="usd">500000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i1ad59cf770774b36883e5e3f187962e3_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfOC0zLTEtMS0w_316a70ff-2aee-4367-a9ed-cfb3a152f30b"
      unitRef="usd">500000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="ib8287a44e2c445c2acd186f4936f5772_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfOS0wLTEtMS0wL3RleHRyZWdpb246ZWQ1OGIyMDdjZTgzNGY1OGIwNTcwMzg2NzBkMzJmY2VfNA_283d3e6c-0d5c-4f8b-8b26-ba7e896555dc"
      unitRef="number">0.03125</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ib8287a44e2c445c2acd186f4936f5772_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfOS0xLTEtMS0w_959da130-c4e2-42a0-8669-3b37943c165e"
      unitRef="usd">1000000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i6be009b691aa4576ac79c8915e21298d_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfOS0zLTEtMS0w_2450afa1-9f7e-465b-8eee-8f7af87b23d1"
      unitRef="usd">1000000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i35556fe1ea36409196d95de0bec85fae_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTAtMC0xLTEtMC90ZXh0cmVnaW9uOjZmZWM0ODA3OWI0YjRiNzBhNjIzNjVlZGM0ZDU4YjU4XzQ_4e7fa11c-cacd-4639-86bf-9f25e11c96fc"
      unitRef="number">0.0200</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentFaceAmount
      contextRef="i35556fe1ea36409196d95de0bec85fae_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTAtMC0xLTEtMC90ZXh0cmVnaW9uOjZmZWM0ODA3OWI0YjRiNzBhNjIzNjVlZGM0ZDU4YjU4Xzc_51e6df80-2eb4-4235-850b-93fbf60c1374"
      unitRef="eur">750000000</us-gaap:DebtInstrumentFaceAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i35556fe1ea36409196d95de0bec85fae_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTAtMS0xLTEtMA_92539352-146d-4f3d-8366-9da993612d69"
      unitRef="usd">869000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="iee3ca7ca07cc4b1b82dc3946ebca7fda_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTAtMy0xLTEtMA_eb310170-0ae0-4fe6-8e47-c6b9b8a13b5f"
      unitRef="usd">916000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i52dee93b650b4cd8868ed20f7cf964bc_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTEtMC0xLTEtMC90ZXh0cmVnaW9uOjIwN2M0Y2ViMzE1NDQ0MDQ4MzNhZjI2MjRkMzBjYTZhXzQ_7498db3e-5eb1-47c6-b324-8e2ac7fb2732"
      unitRef="number">0.0260</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i52dee93b650b4cd8868ed20f7cf964bc_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTEtMS0xLTEtMA_f6b35400-741b-472b-91c2-27a2441bff48"
      unitRef="usd">1250000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i98166ba2f34643ffafa2e088bf573187_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTEtMy0xLTEtMA_f9a59548-94a7-4837-8f96-37ec3074e60f"
      unitRef="usd">1250000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="ib9a2ddc95a504747aa69a99a4d875fea_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTItMC0xLTEtMC90ZXh0cmVnaW9uOjU5ZWQ4MDRhZjViMTQyZTdiZjg1MTQ3ZjgyNjBkMjQ3XzQ_a1f4a18b-56c4-4bc7-86ac-86ecec6cd778"
      unitRef="number">0.0550</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentFaceAmount
      contextRef="ib9a2ddc95a504747aa69a99a4d875fea_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTItMC0xLTEtMC90ZXh0cmVnaW9uOjU5ZWQ4MDRhZjViMTQyZTdiZjg1MTQ3ZjgyNjBkMjQ3Xzc_0ba14d0f-766b-4569-a2da-bfe87f70dc81"
      unitRef="gbp">475000000</us-gaap:DebtInstrumentFaceAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ib9a2ddc95a504747aa69a99a4d875fea_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTItMS0xLTEtMA_3d7b72e8-3667-4ea0-98e6-ba80e12265eb"
      unitRef="usd">640000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ic87056a5fa024aba8b55cbd31c06353a_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTItMy0xLTEtMA_e37654ef-42d9-4728-b507-9e2840255311"
      unitRef="usd">649000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i5285c4d278d54713b60c0cc0f87aa46a_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTMtMC0xLTEtMC90ZXh0cmVnaW9uOjJlY2Y0MjQzM2IxYTQzNDM5NGE4MjFhNmFlOGZjNzIxXzQ_b1e08b8c-47a3-4b68-a8f0-c5dea1833b63"
      unitRef="number">0.0220</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i5285c4d278d54713b60c0cc0f87aa46a_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTMtMS0xLTEtMA_9206508c-ecdd-480d-be02-5d9e70dcb831"
      unitRef="usd">1750000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i6bb96c6e9f4048dfa94c91a4ab648b6a_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTMtMy0xLTEtMA_de906531-c75a-4390-8362-dc1afb7eba4d"
      unitRef="usd">1750000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i705890d8cae541638f21f7669dbe4b04_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTQtMC0xLTEtMC90ZXh0cmVnaW9uOmEzYjczY2E0NDZhMzQ4ZjJhNzZiZmY2YjVlY2JiMjlkXzQ_ea5cb5db-e0fc-4969-a7f3-e558df922eba"
      unitRef="number">0.0320</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i705890d8cae541638f21f7669dbe4b04_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTQtMS0xLTEtMA_a5b7a7e1-ac67-4fcd-be5a-fb2f3b41a08e"
      unitRef="usd">1000000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ieb62499093c345529236e71f444d0853_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTQtMy0xLTEtMA_30f7945b-809f-4510-a49b-772c602720e1"
      unitRef="usd">1000000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="ibda3099c78a845a98d23ce711d8447f6_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTUtMC0xLTEtNDk1OS90ZXh0cmVnaW9uOmMzNjBkMDA2ZGE1YTQ4NTc4N2M4YjQ0ZjZmODFkMzhjXzc2OTY1ODEzOTQ0ODI_fff2d3a5-3aa1-4bec-a367-54dfa44096da"
      unitRef="number">0.0165</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ibda3099c78a845a98d23ce711d8447f6_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTUtMS0xLTEtNTE0Mw_8372be6c-69ad-4f6f-b86d-25f0e8fd9b56"
      unitRef="usd">1250000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ibb2e9e5c4f2a4bbf841a6bc671651b19_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTUtMy0xLTEtNTE0Mw_5ded548a-54a1-458a-84a8-b794bd8fa9d4"
      unitRef="usd">0</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i407ab77f9d0440acae9fe2fc19c63542_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTUtMC0xLTEtMC90ZXh0cmVnaW9uOjlhZjQxMTQ4MGUzZTRhZDNiYzUyYmFmYmVhMTMzOTkxXzQ_2e1e3d48-61a2-4f5f-8ba7-3c4226993a4c"
      unitRef="number">0.0400</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentFaceAmount
      contextRef="i407ab77f9d0440acae9fe2fc19c63542_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTUtMC0xLTEtMC90ZXh0cmVnaW9uOjlhZjQxMTQ4MGUzZTRhZDNiYzUyYmFmYmVhMTMzOTkxXzc_642d70c5-e7f3-458b-ad26-b95a91199a22"
      unitRef="gbp">700000000</us-gaap:DebtInstrumentFaceAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i407ab77f9d0440acae9fe2fc19c63542_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTUtMS0xLTEtMA_b5437edc-bc52-4252-8a5f-91c8df51a50c"
      unitRef="usd">943000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i000f9a5c0b8f4cd99faa556d2ea850e6_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTUtMy0xLTEtMA_46efea7c-cbea-44a3-8805-14e4f2731e95"
      unitRef="usd">957000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="ia3569d0c6bcd4203a1148cb8dda584fe_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTYtMC0xLTEtMC90ZXh0cmVnaW9uOjdkZTc0NTZjNGQzZTRmNDY5ZDVjYzEyMzk0ZWUxNDc0XzQ_36870ca1-3750-417f-acc7-dfac96f50a42"
      unitRef="number">0.0245</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ia3569d0c6bcd4203a1148cb8dda584fe_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTYtMS0xLTEtMA_83aede98-2ccb-461a-9a12-013123ff344f"
      unitRef="usd">1250000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="id46fc442a7f34ba2afc285c190d4a3c5_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTYtMy0xLTEtMA_64670b3c-da24-4c7d-964d-2fbada459a85"
      unitRef="usd">1250000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i2c54babb8e9f4eb8b43722a88181da66_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTctMC0xLTEtMC90ZXh0cmVnaW9uOjVhZGRkNTJiMzNiMDQ1NjU4NGQ2YmJmNDMyMWYzYTZjXzQ_19c0ff62-066b-4d05-89aa-a17d82a0507e"
      unitRef="number">0.0230</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i2c54babb8e9f4eb8b43722a88181da66_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTctMS0xLTEtMA_f6607fb1-7d64-4e29-9022-fe1a598139e3"
      unitRef="usd">1250000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i2f896bd90bd24cfcbf6f31271e9148e9_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTctMy0xLTEtMA_246f6ca7-f163-41c4-bc6e-05d6060a630f"
      unitRef="usd">1250000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i220407dac7c34df4809bfc677b8b3503_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTktMC0xLTEtNTYwNC90ZXh0cmVnaW9uOjI4MmJhNTYzNzgwZjQ5MWY4MDMxZjE4MDIxOGU3MGQwXzgyNDYzMzcyMDgzNjg_99fb8d5e-31f8-4ccd-8041-61c4ae49de70"
      unitRef="number">0.0200</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i220407dac7c34df4809bfc677b8b3503_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTktMS0xLTEtNTA4OA_26b5c033-93d9-4745-b928-57c79b517d3a"
      unitRef="usd">1250000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i10faa7c13c3447bbbc7cfae536e3c802_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTgtMC0xLTEtMC90ZXh0cmVnaW9uOmQ4MDVmNGRlMmM2YzQ1ODk5NGY2N2M1NGJhNzNlMGNkXzQ_8afc6e19-1c59-480d-a69b-bf8f2a9b31c3"
      unitRef="number">0.06375</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i10faa7c13c3447bbbc7cfae536e3c802_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTgtMS0xLTEtMA_a9c52a8f-15f2-4859-9fa5-f5b9e9a5953c"
      unitRef="usd">478000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ia6787d1b183a4eaf8408dbce1815a07c_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTgtMy0xLTEtMA_b8098161-bb75-43ee-ad81-9fb864a9ea7d"
      unitRef="usd">478000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="iac7d798f49894466bc42c0153cdf0595_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTktMC0xLTEtMC90ZXh0cmVnaW9uOmE1MWU1OTIzMzYwMTQxMjVhMTIxOTEzZTQ4MjY4NjkxXzQ_c3fb5360-a220-432b-b55f-5f9ef922292e"
      unitRef="number">0.0690</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="iac7d798f49894466bc42c0153cdf0595_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTktMS0xLTEtMA_126301c0-a107-40ef-af50-7a0972911e22"
      unitRef="usd">254000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ib5e6389f8cf6478dbebef3136cee8c23_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMTktMy0xLTEtMA_3b3a4b44-f141-4df6-84ba-a9eaf180b9ea"
      unitRef="usd">254000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i512d102f92cd4cc2833291c7e8cd520d_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjAtMC0xLTEtMC90ZXh0cmVnaW9uOjczY2JiYTliMTE0MTQzNDRiY2FiMzdiZDVlYzQ2YWRjXzQ_ee31a9e9-db6a-4dca-bcd4-122991d8ec78"
      unitRef="number">0.0640</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i512d102f92cd4cc2833291c7e8cd520d_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjAtMS0xLTEtMA_68641350-ad6d-45d7-acce-564b90f581fb"
      unitRef="usd">333000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i6af736050aa24649ab1cfff13dee1b92_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjAtMy0xLTEtMA_536290b3-9f19-4a92-8cc1-a3669af63408"
      unitRef="usd">333000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i99981976037d4cef90e95f33441854b2_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjEtMC0xLTEtMC90ZXh0cmVnaW9uOjkxZjE1ZjdmMTIzNDQ1NmJhNTIwYzkwYWU0N2JhY2NiXzQ_7387450e-c06e-4384-96fd-0300111dcc23"
      unitRef="number">0.0315</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i99981976037d4cef90e95f33441854b2_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjEtMS0xLTEtMA_190c671a-72ba-411a-b5c2-f17c84a56438"
      unitRef="usd">2000000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="id540a747481347329775d9396bb889d2_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjEtMy0xLTEtMA_34349e7f-763d-4778-a7c3-991ac4099596"
      unitRef="usd">2000000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i00fb0934241248439eae35efb4b7888e_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjItMC0xLTEtMC90ZXh0cmVnaW9uOmYxMjg4NWVjZWY0ZjQwYTE5MDEwYjFhMWZiMjg3NTQzXzQ_9b414dfc-b537-4c26-b559-da542f4513c0"
      unitRef="number">0.0575</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i00fb0934241248439eae35efb4b7888e_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjItMS0xLTEtMA_e4299913-0d7b-47b3-b125-199c88f54be5"
      unitRef="usd">373000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ib61d19755e0742c09a249871a640ecd1_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjItMy0xLTEtMA_e5256e6f-4046-44d3-951c-5ddee1c78c96"
      unitRef="usd">373000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="id14f137f4c5e454687d4fbce9656c938_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjUtMC0xLTEtNTI1Ni90ZXh0cmVnaW9uOjc0YzcxNjE2ZjQ2YTRmZGQ4OWVhN2NjYWI3NWU5MGNhXzc2OTY1ODEzOTQ0Nzk_71f1018d-9c22-4f62-bc85-dd25c1b00215"
      unitRef="number">0.0280</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="id14f137f4c5e454687d4fbce9656c938_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjUtMS0xLTEtNTA1NA_6144ef09-7a10-4308-b6f0-56c10a50fa7d"
      unitRef="usd">1150000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="id4a29b7b702446d0b6a2302a87559c9a_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjMtMC0xLTEtMC90ZXh0cmVnaW9uOjM2YmYxZDRlM2NlMDRmYWQ5OGE5MjNiMGEwNGM3NTllXzQ_846d996c-bcb4-4019-9643-7a6e814d1e99"
      unitRef="number">0.0495</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="id4a29b7b702446d0b6a2302a87559c9a_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjMtMS0xLTEtMA_05c75ab9-6c35-4662-ad65-7ee2d5d445d6"
      unitRef="usd">600000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i891f05772784463faf20ad97f433010d_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjMtMy0xLTEtMA_eb1a2930-48f2-4b98-9462-30a1b4023447"
      unitRef="usd">600000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i1175ce0d1778434ab2f82d1aeb58bf2e_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjQtMC0xLTEtMC90ZXh0cmVnaW9uOjFmZTUxMGUxZjY3OTQzYTRhYWViNTU3M2RlMjRhOGIyXzQ_4ac5cb80-1afb-4396-995a-f21ed9928658"
      unitRef="number">0.0515</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i1175ce0d1778434ab2f82d1aeb58bf2e_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjQtMS0xLTEtMA_2a756784-696c-473f-ba2f-cdb408417149"
      unitRef="usd">729000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="iad10456565dc49e7bc078124e8cd8fe1_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjQtMy0xLTEtMA_d410481d-7753-4b21-b608-036c7db49f1c"
      unitRef="usd">729000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="ia5815daee6a4476eba6259b8d47fe654_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjUtMC0xLTEtMC90ZXh0cmVnaW9uOjUxZjViN2QzZTQyODRlNmQ5MTJlZGQ0ZmEwNzJkNGQyXzQ_144bd1aa-0ea9-4dcb-9feb-b6d08cad4dde"
      unitRef="number">0.0565</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ia5815daee6a4476eba6259b8d47fe654_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjUtMS0xLTEtMA_da989ebd-b4f9-4912-a048-3ec258be5b0e"
      unitRef="usd">415000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i5dfbce0b73c242c8baa5ce827dad9a2c_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjUtMy0xLTEtMA_7dfe5b2c-6c17-4dec-83cc-f80b3db1b294"
      unitRef="usd">415000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="if7316ee9f235452f8616207596971771_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjYtMC0xLTEtMC90ZXh0cmVnaW9uOjYzZWEyZGNjZWY0ZjQzMDU4NDc3ZjI0NjMwNjU1Yzc4XzQ_c1c1094b-13c8-426a-a71e-b356cb25a998"
      unitRef="number">0.05375</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="if7316ee9f235452f8616207596971771_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjYtMS0xLTEtMA_39f32e99-d985-42fe-beed-c863a10a4fd5"
      unitRef="usd">185000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i1675c34a9e9f402db5c00ceb852bb0b6_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjYtMy0xLTEtMA_5c7602ba-8bb7-4e7f-b553-2ad72c605e6f"
      unitRef="usd">185000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i0fd6f6c0e19b45a0b4db95bced8c11a2_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjctMC0xLTEtMC90ZXh0cmVnaW9uOmIwMTRjODdiYzkyYzQ4ODhiOGFiYzZkMTJmMTcyMjI1XzQ_8272cc84-1541-43f4-b56e-981a4d768257"
      unitRef="number">0.0440</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i0fd6f6c0e19b45a0b4db95bced8c11a2_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjctMS0xLTEtMA_5b9bde14-2f98-4b99-b15e-fc9b8736bad6"
      unitRef="usd">2250000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i93a7eb973f5245969d84a7be7e597722_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjctMy0xLTEtMA_f7b9f2cc-f87e-4c15-92fd-17e17306dfc7"
      unitRef="usd">2250000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="ied462f3ca0734341b45ec582dc99c7cf_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjgtMC0xLTEtMC90ZXh0cmVnaW9uOmQ4YTc1ZDQ4YTZkOTQwYjVhYjQzZTJjMDJjNGMzMWQwXzQ_2dd28c99-e34a-4f2b-be59-4dbd9c6323c8"
      unitRef="number">0.04563</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="ied462f3ca0734341b45ec582dc99c7cf_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjgtMS0xLTEtMA_b0f44ddb-3ee2-4910-94fb-542d2d1d4128"
      unitRef="usd">1415000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i3a969d07d31f43ee8b8793eb8498e57b_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjgtMy0xLTEtMA_6bd1fa3a-75c7-4936-9127-d86dc82839a9"
      unitRef="usd">1415000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i27a15eba71944c9f9d27a09b187b5445_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjktMC0xLTEtMC90ZXh0cmVnaW9uOmY1OWE4ZTk5NjVmODQ5MTBiYmNjYTBlZTBjODU5NDJjXzQ_88e82543-827a-4aa9-b894-9eec41231d89"
      unitRef="number">0.03375</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i27a15eba71944c9f9d27a09b187b5445_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjktMS0xLTEtMA_69acfbeb-6ec8-4045-ab86-f737afa40e40"
      unitRef="usd">2250000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="if178d7d786ea47c094645c6a4aac66f9_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMjktMy0xLTEtMA_32946b2b-4902-4adb-a356-922d29256f25"
      unitRef="usd">2250000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="iceaad247ba05416ca273ec699ead3eb8_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzAtMC0xLTEtMC90ZXh0cmVnaW9uOmI1NmM5YzVmOGM3MzRlOGQ5MmM0MjA3NWU5Zjc5ODkxXzQ_99a5a96d-7b93-46c5-a8ee-f1ef98206546"
      unitRef="number">0.04663</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="iceaad247ba05416ca273ec699ead3eb8_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzAtMS0xLTEtMA_848ba306-22ad-4f97-9e06-17a38ed7e5f4"
      unitRef="usd">3541000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i36d572d0be7b4f45b4a95c96ad590314_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzAtMy0xLTEtMA_ca964c8f-583d-4733-b92b-8cc21a6be290"
      unitRef="usd">3541000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i2471f208310742da8d39936484269aa5_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzQtMC0xLTEtNTMyNi90ZXh0cmVnaW9uOmM1NjM0NDQ4MmI5NzQwZWNhMTk5ZTAwZjViOGMzZjYwXzgyNDYzMzcyMDgzODM_03f6d8ac-1c01-4d69-a500-d42bc5d680d4"
      unitRef="number">0.0300</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i2471f208310742da8d39936484269aa5_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzQtMS0xLTEtNTI5NA_f7372b76-78a7-4684-a034-06b589c41c3b"
      unitRef="usd">1350000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="iabc69f9b3f0d4959883895ba0b604099_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzQtMy0xLTEtNTI5NA_017902f7-f81d-4882-9bad-ebf8229d4d89"
      unitRef="usd">0</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="iab6eca48d1b2444986c10a3c8b80b044_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzEtMC0xLTEtMC90ZXh0cmVnaW9uOjZiZTk5YmEwZGQ0NzQzYjA5MzFhMTkyNzliZjc0OGM2XzQ_c83e1a0f-284e-4d1d-a871-3b1a7cd2e92f"
      unitRef="number">0.0277</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="iab6eca48d1b2444986c10a3c8b80b044_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzEtMS0xLTEtMA_7f064546-33c2-4148-89d8-753fd514b168"
      unitRef="usd">940000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="if155164e9eda4b7494a946338f4c79fb_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzEtMy0xLTEtMA_d6df2351-b2fa-4e69-a448-20608505044c"
      unitRef="usd">940000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i33b3f55471c04aefa2d6d4d4486a0ee1_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzItMS0xLTEtMA_ccf01916-1f1f-4c31-a302-6bc108b5025f"
      unitRef="usd">100000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentCarryingAmount
      contextRef="i98d314d0c5ac49429ee3c71c38d086dc_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzItMy0xLTEtMA_b641f4de-4a5d-4422-a6f5-793638a497b6"
      unitRef="usd">100000000</us-gaap:DebtInstrumentCarryingAmount>
    <us-gaap:DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzMtMS0xLTEtMA_1505cf53-6498-486f-92fa-05cd0613acb2"
      unitRef="usd">1221000000</us-gaap:DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet>
    <us-gaap:DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzMtMy0xLTEtMA_54400ff0-afa4-4655-97aa-d212d4212c3d"
      unitRef="usd">1188000000</us-gaap:DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet>
    <us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzQtMS0xLTEtMA_9f1c374e-f3c3-424b-a7da-19dc3441c568"
      unitRef="usd">371000000</us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease>
    <us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzQtMy0xLTEtMA_0e8855e7-df99-41a9-af6f-8f8cf81d34d5"
      unitRef="usd">566000000</us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease>
    <us-gaap:OtherLongTermDebt
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzUtMS0xLTEtMA_228adf5f-99fa-413e-ad70-f7bf23a95a78"
      unitRef="usd">15000000</us-gaap:OtherLongTermDebt>
    <us-gaap:OtherLongTermDebt
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzUtMy0xLTEtMA_2d3c1714-bff6-4614-b3ba-1c1243c4f1a6"
      unitRef="usd">5000000</us-gaap:OtherLongTermDebt>
    <us-gaap:LongTermDebt
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzYtMS0xLTEtMA_75b1d747-c5ba-4c2b-a63f-dde375434b3b"
      unitRef="usd">37579000000</us-gaap:LongTermDebt>
    <us-gaap:LongTermDebt
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzYtMy0xLTEtMA_7e9c9d82-cca2-4ae6-8631-085091185199"
      unitRef="usd">32986000000</us-gaap:LongTermDebt>
    <us-gaap:LongTermDebtCurrent
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzctMS0xLTEtMA_e0005307-96b7-4dae-9289-07cd440927e5"
      unitRef="usd">4288000000</us-gaap:LongTermDebtCurrent>
    <us-gaap:LongTermDebtCurrent
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzctMy0xLTEtMA_3609a304-6d79-4c58-a0b7-85ccfe4655e6"
      unitRef="usd">91000000</us-gaap:LongTermDebtCurrent>
    <us-gaap:LongTermDebtNoncurrent
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzgtMS0xLTEtMA_54904d7f-1b43-454c-bc6c-435c2e88f22a"
      unitRef="usd">33291000000</us-gaap:LongTermDebtNoncurrent>
    <us-gaap:LongTermDebtNoncurrent
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RhYmxlOjA4NTcyYjZkZjZjNjQ0Nzk4NzNhOWQ1YmFlNmYwYTEwL3RhYmxlcmFuZ2U6MDg1NzJiNmRmNmM2NDQ3OTg3M2E5ZDViYWU2ZjBhMTBfMzgtMy0xLTEtMA_031214c2-5b1e-408f-a6ef-f148f08a1dd3"
      unitRef="usd">32895000000</us-gaap:LongTermDebtNoncurrent>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="ied462f3ca0734341b45ec582dc99c7cf_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfMjAw_1dbf7d78-99fc-45f2-9abe-9d1583d4f68b"
      unitRef="number">0.04563</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="iceaad247ba05416ca273ec699ead3eb8_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfMjE5_5c058352-7dd2-41b2-90a0-b057abafdad7"
      unitRef="number">0.04663</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="iab6eca48d1b2444986c10a3c8b80b044_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfMjQx_907f6496-04e8-4e9b-8124-6ea02c0c579a"
      unitRef="number">0.0277</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentInterestRateEffectivePercentage
      contextRef="ied462f3ca0734341b45ec582dc99c7cf_I20210930"
      decimals="3"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfMjk1_9b61b314-09f0-4c56-b1ef-3945f5926d1a"
      unitRef="number">0.063</us-gaap:DebtInstrumentInterestRateEffectivePercentage>
    <us-gaap:DebtInstrumentInterestRateEffectivePercentage
      contextRef="iceaad247ba05416ca273ec699ead3eb8_I20210930"
      decimals="3"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfMjk5_b1da27f5-1b1c-442c-93cc-244e404e43b5"
      unitRef="number">0.056</us-gaap:DebtInstrumentInterestRateEffectivePercentage>
    <us-gaap:DebtInstrumentInterestRateEffectivePercentage
      contextRef="iab6eca48d1b2444986c10a3c8b80b044_I20210930"
      decimals="3"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfMzA2_95a00e2a-ca08-4f0b-8658-0c78caa3d21c"
      unitRef="number">0.052</us-gaap:DebtInstrumentInterestRateEffectivePercentage>
    <us-gaap:DebtInstrumentFaceAmount
      contextRef="i33a19bf9151948efb174bed3a79387f0_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDE4MA_c0a8a75a-182e-4bbf-9e5d-c192b5e5d229"
      unitRef="usd">5000000000</us-gaap:DebtInstrumentFaceAmount>
    <us-gaap:DebtInstrumentFaceAmount
      contextRef="ibda3099c78a845a98d23ce711d8447f6_I20210930"
      decimals="-7"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDE5NA_9cf4d702-4e57-4ab1-803d-29b8d40f0765"
      unitRef="usd">1250000000</us-gaap:DebtInstrumentFaceAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="ibda3099c78a845a98d23ce711d8447f6_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI2Mg_7ca8ca61-6341-42aa-8770-01422f4e9e6f"
      unitRef="number">0.0165</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentFaceAmount
      contextRef="i220407dac7c34df4809bfc677b8b3503_I20210930"
      decimals="-7"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDIwOQ_c559cc56-2218-40ef-b618-0391c551266e"
      unitRef="usd">1250000000</us-gaap:DebtInstrumentFaceAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i220407dac7c34df4809bfc677b8b3503_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI2OQ_78f0a80e-7f84-4106-8150-b5a86542708d"
      unitRef="number">0.0200</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentFaceAmount
      contextRef="id14f137f4c5e454687d4fbce9656c938_I20210930"
      decimals="-7"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDIyNA_53c36fd9-6b28-4385-b699-d66eef7c1c6d"
      unitRef="usd">1150000000</us-gaap:DebtInstrumentFaceAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="id14f137f4c5e454687d4fbce9656c938_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI3Ng_544741ec-c393-489c-9a2f-29739bc02373"
      unitRef="number">0.0280</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentFaceAmount
      contextRef="i2471f208310742da8d39936484269aa5_I20210930"
      decimals="-7"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDIzOQ_0b94350f-d524-485b-b4a9-ecf5fbf96cd5"
      unitRef="usd">1350000000</us-gaap:DebtInstrumentFaceAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i2471f208310742da8d39936484269aa5_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI4OQ_4f1427d4-3fba-4223-825d-be754be3d716"
      unitRef="number">0.0300</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <amgn:PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent
      contextRef="ifc54ee979f3c450d94595dd648269176_D20210701-20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI1NA_523f8b87-41a8-4243-8997-346eaaf5a1ba"
      unitRef="number">1.01</amgn:PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent>
    <amgn:PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent
      contextRef="id79db748ed1c48398fe671a31ee535e0_D20210701-20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI1NA_8efd579b-8c61-405e-945b-acb09ffd342c"
      unitRef="number">1.01</amgn:PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent>
    <amgn:PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent
      contextRef="ie5587a9964dd43d2a6782cd812ea6608_D20210701-20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI1NA_d247c102-5c07-40cf-a58c-c27290fdb4c4"
      unitRef="number">1.01</amgn:PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent>
    <amgn:PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent
      contextRef="ic6452876c4b84f979e9f7d07007ec855_D20210701-20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfODI0NjMzNzIxMDI1NA_e438867d-d6eb-44a1-b7ec-d97501bb5c04"
      unitRef="number">1.01</amgn:PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent>
    <amgn:DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount
      contextRef="ia312c6387bbf40488704796f2339d92c_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNzY5NjU4MTM5NjQyNQ_d8fef177-0654-43f4-b3c1-9ffc7948772a">P2M</amgn:DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount>
    <amgn:DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount
      contextRef="ic5275f5bc2cf4d60a35166b9ec79a4c2_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNzY5NjU4MTM5NjQ0NA_66de48cb-dc1a-407e-819b-0341a229fe7f">P6M</amgn:DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount>
    <us-gaap:DerivativeNotionalAmount
      contextRef="ia3569d0c6bcd4203a1148cb8dda584fe_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNDMz_b801bc97-a129-418a-a4d3-7b9efb4a7f41"
      unitRef="usd">1000000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="ia3569d0c6bcd4203a1148cb8dda584fe_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNDcy_d53bfa8f-f466-4f22-b676-29401cd1b010"
      unitRef="number">0.0245</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DerivativeBasisSpreadOnVariableRate
      contextRef="i434c36284fce4b0fb4ec413faf8330f4_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNTUz_435f1626-0fe2-4338-a7f3-c47f04d7c4d1"
      unitRef="number">0.010</us-gaap:DerivativeBasisSpreadOnVariableRate>
    <us-gaap:DerivativeNotionalAmount
      contextRef="i2c54babb8e9f4eb8b43722a88181da66_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNTk2_10aee310-d44d-433b-9e55-f30bfbaa3e49"
      unitRef="usd">500000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i2c54babb8e9f4eb8b43722a88181da66_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNjM1_d2829941-42ab-4106-9280-da3ec52d15d2"
      unitRef="number">0.0230</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DerivativeBasisSpreadOnVariableRate
      contextRef="i4eb0394fe4684ccdb9a301bd5115028c_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV81OC9mcmFnOjNjOGFkMDAzMzMyMTQ3Yjc4MmIxNDU2OGRiOGMyNmUxL3RleHRyZWdpb246M2M4YWQwMDMzMzIxNDdiNzgyYjE0NTY4ZGI4YzI2ZTFfNzE2_b58f9b40-0598-4043-8cce-926423078087"
      unitRef="number">0.008</us-gaap:DerivativeBasisSpreadOnVariableRate>
    <us-gaap:StockholdersEquityNoteDisclosureTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfOTQz_fac6f2be-d626-4298-b51f-75344d6c4633">Stockholders&#x2019; equity&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Stock repurchase program&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Activity under our stock repurchase program, on a trade date basis, was as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:42.321%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.496%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.496%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.496%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.501%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Shares&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Dollars&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Shares&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Dollars&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;First quarter&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.7&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;865&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.3&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;933&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Second quarter&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6.5&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,592&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.6&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;591&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Third quarter&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.6&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,069&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.0&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;752&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total stock repurchases&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;14.8&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,526&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9.9&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,276&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;In March 2021, our Board of Directors increased the amount authorized under our stock repurchase program by an additional $3.4&#160;billion. As of September 30, 2021&lt;/span&gt;&lt;span style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;, $2.9 billion of aut&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;horization remained available under our stock repurchase program. &lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;In October 2021, the Board of Directors increased the amount authorized under our stock repurchase program by an additional $4.5 billion.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Dividends&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;In July 2021, March 2021 and December 2020, the Board of Directors declared a quarterly cash dividend of $1.76 per share, which were paid in September 2021, June 2021 and March 2021, respectively. In October 2021, the Board of Directors declared a quarterly cash dividend of $1.76 per share, which will be paid on December 8, 2021.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Accumulated other comprehensive income (loss)&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The components of Accumulated other comprehensive income (loss) (AOCI) were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:45.537%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.987%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.987%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.987%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.987%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.995%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Foreign&lt;br/&gt;currency&lt;br/&gt;translation&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Cash&#160;flow&lt;br/&gt;hedges&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Available-for-sale&lt;br/&gt;securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Other&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;AOCI&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Balance as of December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(709)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(263)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(14)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(985)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency translation adjustments&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(39)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(39)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Unrealized gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;108&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;108&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Reclassification adjustments to income&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;133&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;133&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Income taxes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(51)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(51)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Balance as of March 31, 2021&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(748)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(73)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(13)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(833)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency translation adjustments&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;14&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;14&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Unrealized losses&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(31)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(31)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Reclassification adjustments to income&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(28)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(28)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Income taxes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;11&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;11&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Balance as of June 30, 2021&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(734)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(121)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(14)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(868)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency translation adjustments&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(35)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(35)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Unrealized gains (losses)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;16&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;15&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Reclassification adjustments to income&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;109&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;109&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(3)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(3)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Income taxes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(26)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(26)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Balance as of September 30, 2021&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(769)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(22)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(17)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(808)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;margin-top:7pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Reclassifications out of AOCI and into earnings, including related income tax expenses, were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:39.104%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:14.543%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:14.543%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:25.220%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Three months ended September 30,&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Components of AOCI&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated&lt;br/&gt;Statements of Income locations&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cash flow hedges:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contract (losses) gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(5)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;41&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Product sales&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contract (losses) gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(104)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;183&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(109)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;224&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Income before income taxes&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;23&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(49)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Provision for income taxes&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(86)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;175&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Net income&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Available-for-sale securities:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Net realized gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Provision for income taxes&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Net income&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="9" style="background-color:#ffffff;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Nine months ended September 30,&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Components of AOCI&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated&lt;br/&gt;Statements of Income locations&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cash flow hedges:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contract (losses) gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(24)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;158&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Product sales&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contract (losses) gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(190)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;101&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(214)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;259&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Income before income taxes&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;45&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(57)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Provision for income taxes&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(169)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;202&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Net income&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Available-for-sale securities:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Net realized gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;33&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(7)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Provision for income taxes&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;26&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Net income&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</us-gaap:StockholdersEquityNoteDisclosureTextBlock>
    <amgn:StockRepurchaseProgramTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfOTcy_94d14ea9-0d35-4fe1-b042-4a730f15cc91">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Activity under our stock repurchase program, on a trade date basis, was as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:42.321%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.496%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.496%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.496%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.501%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Shares&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Dollars&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Shares&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Dollars&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;First quarter&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.7&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;865&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.3&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;933&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Second quarter&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6.5&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,592&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.6&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;591&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Third quarter&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.6&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,069&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.0&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;752&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total stock repurchases&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;14.8&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,526&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;9.9&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2,276&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</amgn:StockRepurchaseProgramTableTextBlock>
    <us-gaap:StockRepurchasedDuringPeriodShares
      contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMi0xLTEtMS0w_ca5a1e39-e71e-4b8a-8079-73702ef424dd"
      unitRef="shares">3700000</us-gaap:StockRepurchasedDuringPeriodShares>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="icf54caf0fc7842769e0fe4a917d538ea_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMi0zLTEtMS0w_aa42f987-10c5-4128-b722-12ee1296fee8"
      unitRef="usd">865000000</us-gaap:StockRepurchasedDuringPeriodValue>
    <us-gaap:StockRepurchasedDuringPeriodShares
      contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMi01LTEtMS0w_f49c153a-b48e-4af3-9d54-173fa30e2c54"
      unitRef="shares">4300000</us-gaap:StockRepurchasedDuringPeriodShares>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="i7348d0393dc148e09ad7dc1d41c428bf_D20200101-20200331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMi03LTEtMS0w_9e858b14-8fec-48de-9ddf-c52b47e49105"
      unitRef="usd">933000000</us-gaap:StockRepurchasedDuringPeriodValue>
    <us-gaap:StockRepurchasedDuringPeriodShares
      contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMy0xLTEtMS0w_cc374c76-90ad-4a14-88ea-e312ef0fbca7"
      unitRef="shares">6500000</us-gaap:StockRepurchasedDuringPeriodShares>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="if25ef868ecd240a3b1467e666429713f_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMy0zLTEtMS0w_6b5067da-27e3-4068-8e29-4ba60f748599"
      unitRef="usd">1592000000</us-gaap:StockRepurchasedDuringPeriodValue>
    <us-gaap:StockRepurchasedDuringPeriodShares
      contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMy01LTEtMS0w_bbeb536d-8a9f-4176-a625-53fe8995d143"
      unitRef="shares">2600000</us-gaap:StockRepurchasedDuringPeriodShares>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="ie2deb582f0d74f2fad05be0b39bc5f5c_D20200401-20200630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfMy03LTEtMS0w_531990b4-1b2e-4973-a79e-a568d896e7bb"
      unitRef="usd">591000000</us-gaap:StockRepurchasedDuringPeriodValue>
    <us-gaap:StockRepurchasedDuringPeriodShares
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNC0xLTEtMS0w_442eaedc-03e0-4e72-9a34-f7c167c7f728"
      unitRef="shares">4600000</us-gaap:StockRepurchasedDuringPeriodShares>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNC0zLTEtMS0w_644d31f0-9954-477c-a7c6-da2f23799bd7"
      unitRef="usd">1069000000</us-gaap:StockRepurchasedDuringPeriodValue>
    <us-gaap:StockRepurchasedDuringPeriodShares
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNC01LTEtMS0w_57556fdc-4378-40db-aa5f-f0e32077c4d3"
      unitRef="shares">3000000.0</us-gaap:StockRepurchasedDuringPeriodShares>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNC03LTEtMS0w_89514413-4223-410c-9fb6-8ef05f5c4423"
      unitRef="usd">752000000</us-gaap:StockRepurchasedDuringPeriodValue>
    <us-gaap:StockRepurchasedDuringPeriodShares
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNS0xLTEtMS0w_90a3cbc3-05fb-4107-a7fb-abbd25661de7"
      unitRef="shares">14800000</us-gaap:StockRepurchasedDuringPeriodShares>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNS0zLTEtMS0w_5a6f8b24-ae49-4c8a-9e5d-c8a6d0348ac1"
      unitRef="usd">3526000000</us-gaap:StockRepurchasedDuringPeriodValue>
    <us-gaap:StockRepurchasedDuringPeriodShares
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-5"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNS01LTEtMS0w_f2e761d0-bad2-4a21-9a83-1d500c772b45"
      unitRef="shares">9900000</us-gaap:StockRepurchasedDuringPeriodShares>
    <us-gaap:StockRepurchasedDuringPeriodValue
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjMzMWQ4NmM1NzU0ZTQ4ZDE4NTI4YTEyODY4MGY0NWEwL3RhYmxlcmFuZ2U6MzMxZDg2YzU3NTRlNDhkMTg1MjhhMTI4NjgwZjQ1YTBfNS03LTEtMS0w_81ece32a-43d9-4ca6-a243-ad7e595d83ed"
      unitRef="usd">2276000000</us-gaap:StockRepurchasedDuringPeriodValue>
    <us-gaap:StockRepurchaseProgramAuthorizedAmount1
      contextRef="ibb4ad07750104a41ad551ce7e97f7afe_I20210630"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMjYw_7623c9a3-1e10-40ee-8bb7-bd8e28a65919"
      unitRef="usd">3400000000</us-gaap:StockRepurchaseProgramAuthorizedAmount1>
    <us-gaap:StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMjc0_131744ca-df23-4c02-9bf5-130663d736bc"
      unitRef="usd">2900000000</us-gaap:StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1>
    <us-gaap:CommonStockDividendsPerShareDeclared
      contextRef="i461e1d1d258d4b4faf9c477a92b85a30_D20210301-20210331"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODkzMA_3d65cc63-894e-420a-9b4f-8ecd23f94939"
      unitRef="usdPerShare">1.76</us-gaap:CommonStockDividendsPerShareDeclared>
    <us-gaap:CommonStockDividendsPerShareCashPaid
      contextRef="iccfbc695297d4e6b87ea624adb1a3149_D20210901-20210930"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODkzMA_5fdf3cc6-226f-4d8b-a4eb-daea7fa6fcc0"
      unitRef="usdPerShare">1.76</us-gaap:CommonStockDividendsPerShareCashPaid>
    <us-gaap:CommonStockDividendsPerShareCashPaid
      contextRef="ib619731edd7541fe8568acd19da059d6_D20210601-20210630"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODkzMA_640734ac-be18-46f8-99fd-f5ee46d66cee"
      unitRef="usdPerShare">1.76</us-gaap:CommonStockDividendsPerShareCashPaid>
    <us-gaap:CommonStockDividendsPerShareCashPaid
      contextRef="i461e1d1d258d4b4faf9c477a92b85a30_D20210301-20210331"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODkzMA_7fad2c34-0697-4b09-a8cf-4f8277407bac"
      unitRef="usdPerShare">1.76</us-gaap:CommonStockDividendsPerShareCashPaid>
    <us-gaap:CommonStockDividendsPerShareDeclared
      contextRef="i57518655effb4de5bdcffb7396c85dc7_D20210701-20210731"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODkzMA_c0ca5050-8cbc-4439-a1d5-6b56de8c2df2"
      unitRef="usdPerShare">1.76</us-gaap:CommonStockDividendsPerShareDeclared>
    <us-gaap:CommonStockDividendsPerShareDeclared
      contextRef="idad3dab92e834ac98e9986b58ed4d7d9_D20201201-20201231"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODkzMA_ec0340db-d4f4-42d4-a197-6c7e3c07243b"
      unitRef="usdPerShare">1.76</us-gaap:CommonStockDividendsPerShareDeclared>
    <us-gaap:CommonStockDividendsPerShareDeclared
      contextRef="i0f1af52b3cdc45b69ad881a053131e62_D20211001-20211031"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODk0MA_3f28d309-16bc-4dd6-9999-eb9418073e3d"
      unitRef="usdPerShare">1.76</us-gaap:CommonStockDividendsPerShareDeclared>
    <us-gaap:CommonStockDividendsPerShareCashPaid
      contextRef="i9b08bc2a35ad4f1b92f1a9c32d536e07_D20211208-20211208"
      decimals="2"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfMTA5OTUxMTYyODk0MA_4c06ed0d-d600-4b48-86c1-739b7062ba8b"
      unitRef="usdPerShare">1.76</us-gaap:CommonStockDividendsPerShareCashPaid>
    <us-gaap:ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfOTcz_ae48f3d5-041d-489d-838b-0de09fc329df">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The components of Accumulated other comprehensive income (loss) (AOCI) were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:45.537%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.987%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.987%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.987%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.987%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.995%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Foreign&lt;br/&gt;currency&lt;br/&gt;translation&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Cash&#160;flow&lt;br/&gt;hedges&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Available-for-sale&lt;br/&gt;securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Other&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;AOCI&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Balance as of December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(709)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(263)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(14)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(985)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency translation adjustments&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(39)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(39)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Unrealized gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;108&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;108&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Reclassification adjustments to income&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;133&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;133&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Income taxes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(51)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(51)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Balance as of March 31, 2021&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(748)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(73)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(13)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(833)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency translation adjustments&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;14&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;14&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Unrealized losses&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(31)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(31)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Reclassification adjustments to income&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(28)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(28)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Income taxes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;11&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;11&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Balance as of June 30, 2021&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(734)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(121)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(14)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(868)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency translation adjustments&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(35)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(35)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Unrealized gains (losses)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;16&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(1)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;15&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Reclassification adjustments to income&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;109&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;109&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(3)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(3)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Income taxes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(26)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(26)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;div&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Balance as of September 30, 2021&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(769)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(22)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(17)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(808)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</us-gaap:ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock>
    <us-gaap:StockholdersEquity
      contextRef="i770b083713ae40d5abf6f7e80c8202c5_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMS0xLTEtMS0w_19728695-df3d-4360-adba-987b03ca1c85"
      unitRef="usd">-709000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="ic6813714a49c4e1ebb1c7f61614d435a_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMS0zLTEtMS0w_6fabda9f-7b01-4ee9-a972-9bf411cea1da"
      unitRef="usd">-263000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i8bf4fb9fc5bc4ef5b53a1d2a4b2dbe24_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMS01LTEtMS0w_28b6e27d-6e0a-493a-afb1-638b938594ef"
      unitRef="usd">1000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="if822d7ae834a4a6cbea8ec7441e99f34_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMS03LTEtMS0w_8d208185-7aa7-4378-8013-442a233cf693"
      unitRef="usd">-14000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="iaea9ac2193424d918f03fbf56ef30362_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMS05LTEtMS0w_6679ed05-28d0-465e-960f-65232a1dccb6"
      unitRef="usd">-985000000</us-gaap:StockholdersEquity>
    <us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent
      contextRef="ic640b9e0658f45ddb2d1866ae9c0d679_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMy0xLTEtMS0w_4ac315a0-7d02-4bc4-91e6-4ed5c623d229"
      unitRef="usd">-39000000</us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent>
    <us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent
      contextRef="i8ff5ee6ed2904950abde3e69e298a888_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMy05LTEtMS0w_c5f01445-21b1-4d70-9235-700c688bac2c"
      unitRef="usd">-39000000</us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent>
    <us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent
      contextRef="i362a946d783d4675a1537219335e1ecf_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNC0zLTEtMS0w_16a91f21-2c33-4155-b80e-f1a1652839dd"
      unitRef="usd">108000000</us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent>
    <us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent
      contextRef="i3490a417c3664ea28df867c0b5b64b99_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNC01LTEtMS0w_2f85354f-a145-478c-b488-bc7dc08004d0"
      unitRef="usd">0</us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent>
    <us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent
      contextRef="i4f043f0296ab40adbbd000e3a19b8263_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNC03LTEtMS0w_80283aaf-a864-4cd6-a422-e0979849dc8a"
      unitRef="usd">0</us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent>
    <us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent
      contextRef="i8ff5ee6ed2904950abde3e69e298a888_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNC05LTEtMS0w_e05f5a8c-fdd3-4b62-bbc2-edb3bd08d71b"
      unitRef="usd">108000000</us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent>
    <us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent
      contextRef="i362a946d783d4675a1537219335e1ecf_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNS0zLTEtMS0w_31196791-1059-46f3-aa9b-edb424071476"
      unitRef="usd">133000000</us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent>
    <us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent
      contextRef="i3490a417c3664ea28df867c0b5b64b99_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNS01LTEtMS0w_e6f28df0-ad85-4cbc-a20d-ee8bd9c4fe8d"
      unitRef="usd">0</us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent>
    <us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent
      contextRef="i8ff5ee6ed2904950abde3e69e298a888_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNS05LTEtMS0w_b9beb08f-0959-40be-9c50-37a925d6a09d"
      unitRef="usd">133000000</us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent>
    <amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax
      contextRef="i4f043f0296ab40adbbd000e3a19b8263_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNi03LTEtMS0w_5095bc67-d829-4c58-82ce-bb0b6920f99b"
      unitRef="usd">1000000</amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax>
    <amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax
      contextRef="i8ff5ee6ed2904950abde3e69e298a888_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNi05LTEtMS0w_2b395b9d-4644-412c-b3ae-5bc2b1de2ae2"
      unitRef="usd">1000000</amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax>
    <us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1
      contextRef="ic640b9e0658f45ddb2d1866ae9c0d679_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNy0xLTEtMS0w_8bd428ef-6933-49ae-8873-5298a21f6685"
      unitRef="usd">0</us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1>
    <us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1
      contextRef="i362a946d783d4675a1537219335e1ecf_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNy0zLTEtMS0w_af52ca12-6f5f-4ff7-8a07-6bc0e84a3e11"
      unitRef="usd">-51000000</us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1>
    <us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1
      contextRef="i3490a417c3664ea28df867c0b5b64b99_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNy01LTEtMS0w_b4ab33ea-8fd8-442f-bf84-e30095328591"
      unitRef="usd">0</us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1>
    <us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1
      contextRef="i8ff5ee6ed2904950abde3e69e298a888_D20210101-20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfNy05LTEtMS0w_4eb423cc-3634-4ce4-a5a5-1dc9b8087076"
      unitRef="usd">-51000000</us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1>
    <us-gaap:StockholdersEquity
      contextRef="i3cb26c116a8243b290d914005b2701d7_I20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfOC0xLTEtMS0w_8e93dcff-8f04-42a5-9177-c3a101e31d36"
      unitRef="usd">-748000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i1bc84cd5a4d7427f8ea0603f5c4fab36_I20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfOC0zLTEtMS0w_57a1f7c0-3983-4f6e-bbc7-63f3a30c186a"
      unitRef="usd">-73000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i12d709ededf44d88909a52a34d1b6465_I20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfOC01LTEtMS0w_da733f7e-4069-4ca2-bc96-1aba393acefb"
      unitRef="usd">1000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i36d381395cab48a3a0a38dacd23b095d_I20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfOC03LTEtMS0w_7bf3e73b-0d11-45a4-8269-f7de7ccff8a2"
      unitRef="usd">-13000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i02d7483a082146bca57a490cca649110_I20210331"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfOC05LTEtMS0w_6953129c-abe8-4f8d-8a53-7c2445000d98"
      unitRef="usd">-833000000</us-gaap:StockholdersEquity>
    <us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent
      contextRef="i77c6d51206434679bcbf62756fdc2646_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTAtMS0xLTEtMA_705c97f9-c6b1-4973-a6de-b6a8ae31c667"
      unitRef="usd">14000000</us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent>
    <us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent
      contextRef="ic34d84ceeae14872821180cf4d7c1fc9_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTAtOS0xLTEtMA_a74ecd68-6df4-427e-a989-a36bf35d954f"
      unitRef="usd">14000000</us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent>
    <us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent
      contextRef="ic28cfd96645b4c7caed54e18d250141a_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTEtMy0xLTEtMA_70c2182a-de23-4211-855a-f13d8afc8fef"
      unitRef="usd">-31000000</us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent>
    <us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent
      contextRef="i132b85ef12554699b07d3501175ff54f_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTEtNS0xLTEtMA_a117cb19-3ffb-4ab4-aeaa-a708e8bf7026"
      unitRef="usd">0</us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent>
    <us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent
      contextRef="if0969aa8ef414908986e6dbb1310e704_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTEtNy0xLTEtMA_27cd91a7-5b1d-496f-b331-778ad8a65a81"
      unitRef="usd">0</us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent>
    <us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent
      contextRef="ic34d84ceeae14872821180cf4d7c1fc9_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTEtOS0xLTEtMA_da3de595-8d7b-41fe-b260-824b930e3dcb"
      unitRef="usd">-31000000</us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent>
    <us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent
      contextRef="ic28cfd96645b4c7caed54e18d250141a_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTItMy0xLTEtMA_b889429d-1c9f-4613-bef8-a46a6bed0c2d"
      unitRef="usd">-28000000</us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent>
    <us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent
      contextRef="i132b85ef12554699b07d3501175ff54f_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTItNS0xLTEtMA_337d0fd1-5de7-4fe3-9c3a-38b26fc79309"
      unitRef="usd">0</us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent>
    <us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent
      contextRef="ic34d84ceeae14872821180cf4d7c1fc9_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTItOS0xLTEtMA_7f5b7115-90a6-4086-bb20-f2036b96927e"
      unitRef="usd">-28000000</us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent>
    <amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax
      contextRef="if0969aa8ef414908986e6dbb1310e704_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTMtNy0xLTEtMA_567e9d44-1e88-4b70-99d6-a94df2dedccd"
      unitRef="usd">-1000000</amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax>
    <amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax
      contextRef="ic34d84ceeae14872821180cf4d7c1fc9_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTMtOS0xLTEtMA_86881443-1fa4-4d5d-abfb-532306b806ea"
      unitRef="usd">-1000000</amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax>
    <us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1
      contextRef="i77c6d51206434679bcbf62756fdc2646_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTQtMS0xLTEtMA_fe68093a-dc4f-4836-baad-25bf6d86cba0"
      unitRef="usd">0</us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1>
    <us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1
      contextRef="ic28cfd96645b4c7caed54e18d250141a_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTQtMy0xLTEtMA_0e8544f6-1772-4d9a-aaa8-34d4d6f6efc4"
      unitRef="usd">11000000</us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1>
    <us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1
      contextRef="i132b85ef12554699b07d3501175ff54f_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTQtNS0xLTEtMA_620bfd21-4a3f-4582-a4f2-d36dc0d6c96f"
      unitRef="usd">0</us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1>
    <us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1
      contextRef="ic34d84ceeae14872821180cf4d7c1fc9_D20210401-20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTQtOS0xLTEtMA_a6f150d7-5ddf-4812-b641-199476b345fb"
      unitRef="usd">11000000</us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1>
    <us-gaap:StockholdersEquity
      contextRef="ia5b73fcb215b4f1fb5f74cc40aac6a12_I20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTUtMS0xLTEtMA_fd09c747-6540-4ee1-a1c2-b5d26432ba67"
      unitRef="usd">-734000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="if425fe5fd2294df9a8d0f639c5037ec9_I20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTUtMy0xLTEtMA_ba552bb9-5d31-4cda-8374-977cc01d42f7"
      unitRef="usd">-121000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="id85f7578a3bc49ca89f363dce5fb32aa_I20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTUtNS0xLTEtMA_0d02c68b-298a-4619-be07-28ba9cc00bfa"
      unitRef="usd">1000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i0fdb28b3619543a79bc3b17b1cc0a2d4_I20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTUtNy0xLTEtMA_737e9bf2-1777-4115-87f3-dbd2541e95d1"
      unitRef="usd">-14000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i9d079f6d807e45a8b0ea7b4bf5ca1b1c_I20210630"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTUtOS0xLTEtMA_1668280b-8fa5-43c3-a6f0-15198ba9371f"
      unitRef="usd">-868000000</us-gaap:StockholdersEquity>
    <us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent
      contextRef="ief03f026e49a44918a54a590451e6db3_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTYtMS0xLTEtMA_56cc4cc9-86ed-4787-a037-bbe6b02c0a8d"
      unitRef="usd">-35000000</us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent>
    <us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent
      contextRef="i984e708e2ca94952a077181e38e25d78_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTYtOS0xLTEtMA_5b254c93-c40a-4efd-83ef-f22cfd3c6107"
      unitRef="usd">-35000000</us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent>
    <us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent
      contextRef="i98ef59b24516466ebfc3d73a98308ecf_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTctMy0xLTEtMA_183495b8-6722-45dd-8620-b4a70ad46eff"
      unitRef="usd">16000000</us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent>
    <us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent
      contextRef="i719883141b814809a34bc70ed81e53a0_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTctNS0xLTEtMA_28869821-cda1-474d-bddf-e00857b99478"
      unitRef="usd">-1000000</us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent>
    <us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent
      contextRef="i45a15717cb5141c5864e39d52a2a95fc_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTctNy0xLTEtMA_65b6a705-4732-4dd7-b3c8-b44262ffbcdf"
      unitRef="usd">0</us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent>
    <us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent
      contextRef="i984e708e2ca94952a077181e38e25d78_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTctOS0xLTEtMA_66649184-6b61-4934-91bf-e409801ce7db"
      unitRef="usd">15000000</us-gaap:OciBeforeReclassificationsBeforeTaxAttributableToParent>
    <us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent
      contextRef="i98ef59b24516466ebfc3d73a98308ecf_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTgtMy0xLTEtMA_77c9b7e4-334a-4f4a-8de5-6ca68929cf47"
      unitRef="usd">109000000</us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent>
    <us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent
      contextRef="i719883141b814809a34bc70ed81e53a0_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTgtNS0xLTEtMA_9d2eb7e6-2ba6-4e79-9f23-307b02b9aad3"
      unitRef="usd">0</us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent>
    <us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent
      contextRef="i984e708e2ca94952a077181e38e25d78_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTgtOS0xLTEtMA_b74da7ab-19a8-41d5-b3cc-a83e6fb34dd4"
      unitRef="usd">109000000</us-gaap:ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent>
    <amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax
      contextRef="i45a15717cb5141c5864e39d52a2a95fc_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTktNy0xLTEtMA_0379cee9-1cd8-48db-bb7f-c1dc6b1474fe"
      unitRef="usd">-3000000</amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax>
    <amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax
      contextRef="i984e708e2ca94952a077181e38e25d78_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMTktOS0xLTEtMA_8e2d8a11-2b82-4c54-86c7-e92d16c8ade5"
      unitRef="usd">-3000000</amgn:OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax>
    <us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1
      contextRef="ief03f026e49a44918a54a590451e6db3_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjAtMS0xLTEtMA_1da97942-c963-40d9-aca3-effbfd9a5c9d"
      unitRef="usd">0</us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1>
    <us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1
      contextRef="i98ef59b24516466ebfc3d73a98308ecf_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjAtMy0xLTEtMA_43797279-e738-4020-82a8-9da6a3fc9e58"
      unitRef="usd">-26000000</us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1>
    <us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1
      contextRef="i719883141b814809a34bc70ed81e53a0_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjAtNS0xLTEtMA_80162588-5817-44f7-b29f-4ca531ee1cf9"
      unitRef="usd">0</us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1>
    <us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1
      contextRef="i984e708e2ca94952a077181e38e25d78_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjAtOS0xLTEtMA_24281e17-30bd-4fe6-a595-0afa5ff12d06"
      unitRef="usd">-26000000</us-gaap:OtherComprehensiveIncomeLossTaxPortionAttributableToParent1>
    <us-gaap:StockholdersEquity
      contextRef="ieede5746b0d64fdbbf75791dacc0ef9d_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjEtMS0xLTEtMA_f2a7cf4a-5f3d-437a-984d-0e7fce6a3ddd"
      unitRef="usd">-769000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i672a17c30f404de680e008be9b6464aa_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjEtMy0xLTEtMA_e41f20d7-170f-44d8-9287-8a442cd65574"
      unitRef="usd">-22000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i9660b813f8e644d8b66ad3118538f278_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjEtNS0xLTEtMA_198bdc04-ff4b-4ae1-b009-df09775c6a58"
      unitRef="usd">0</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="i24a9272b1ce44928aa5b6ba2a3c47e9f_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjEtNy0xLTEtMA_4fe3a041-090e-463a-add6-5f9fffa9d907"
      unitRef="usd">-17000000</us-gaap:StockholdersEquity>
    <us-gaap:StockholdersEquity
      contextRef="ic860f31327384ad08f5dbf6d59cdb763_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjk4OWI3YjhhOWQyNDQ2YjViYTI0YWRkOWMxMGQxYThmL3RhYmxlcmFuZ2U6OTg5YjdiOGE5ZDI0NDZiNWJhMjRhZGQ5YzEwZDFhOGZfMjEtOS0xLTEtMA_7d42a4c3-0483-4b07-8aab-9fc223549db2"
      unitRef="usd">-808000000</us-gaap:StockholdersEquity>
    <us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RleHRyZWdpb246NmQ2NTBjNDE0ZTcxNDhlNmFhMGE5MTdmYThjNjdkMjdfOTM1_e197ed1b-4cb7-4dfc-b764-a546c97c0ced">&lt;div style="margin-bottom:8pt;margin-top:7pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Reclassifications out of AOCI and into earnings, including related income tax expenses, were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:39.104%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:14.543%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:14.543%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:25.220%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Three months ended September 30,&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Components of AOCI&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated&lt;br/&gt;Statements of Income locations&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cash flow hedges:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contract (losses) gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(5)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;41&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Product sales&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contract (losses) gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(104)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;183&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(109)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;224&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Income before income taxes&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;23&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(49)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Provision for income taxes&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(86)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;175&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Net income&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Available-for-sale securities:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Net realized gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Provision for income taxes&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Net income&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="9" style="background-color:#ffffff;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Nine months ended September 30,&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Components of AOCI&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated&lt;br/&gt;Statements of Income locations&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cash flow hedges:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contract (losses) gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(24)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;158&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Product sales&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contract (losses) gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(190)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;101&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(214)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;259&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Income before income taxes&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;45&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(57)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Provision for income taxes&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(169)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;202&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Net income&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Available-for-sale securities:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Net realized gains&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;33&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(7)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Provision for income taxes&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;26&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Net income&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i32d3947cf2c945deb867f411799b6962_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMy0yLTEtMS0w_f1229e8d-1280-4be6-9c17-08794318f31a"
      unitRef="usd">-5000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i671c24fb8d22406aa2608b0eaf66e7ea_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMy00LTEtMS0w_8b0203f0-cf93-439c-aba7-d2026d025905"
      unitRef="usd">41000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i605067db02764f2ca67c7def81eb8b61_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfNC0yLTEtMS0w_fe49ce8b-4916-4b8e-b5ef-e343aa56f617"
      unitRef="usd">-104000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i956f0c0215934258b02d8cc62b9f996d_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfNC00LTEtMS0w_16794c32-9b60-4702-80ea-fdfe35cf305f"
      unitRef="usd">183000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments
      contextRef="i774914ff61704f25a808fe591907f07a_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfNi0yLTEtMS0w_09e7e58d-8fa0-4c55-94f2-00cc8bea979c"
      unitRef="usd">-109000000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments
      contextRef="i3bd653c39f1d495b9c484952593554a1_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfNi00LTEtMS0w_38562b15-64c0-4c5d-91df-e86aef615b26"
      unitRef="usd">224000000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="i774914ff61704f25a808fe591907f07a_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfNy0yLTEtMS0w_5e75099e-cba6-435d-8f83-5a906f80bf0b"
      unitRef="usd">-23000000</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="i3bd653c39f1d495b9c484952593554a1_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfNy00LTEtMS0w_64e0f217-b29e-4f48-b09c-9e0b9480e45b"
      unitRef="usd">49000000</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:NetIncomeLoss
      contextRef="i774914ff61704f25a808fe591907f07a_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfOC0yLTEtMS0w_fea58ec8-5720-4229-9439-0934cafe538e"
      unitRef="usd">-86000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="i3bd653c39f1d495b9c484952593554a1_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfOC00LTEtMS0w_0dc4f723-1827-43a9-bcea-7cf6eb802686"
      unitRef="usd">175000000</us-gaap:NetIncomeLoss>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i66702e11ddcd4d94b4f6a53b4231f09f_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTAtMi0xLTEtMA_45f9b649-f66c-46a7-8ea3-6f11d2e1576d"
      unitRef="usd">0</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="ice9f1dfc8f83445b9b89ebcebe763f1a_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTAtNC0xLTEtMA_c7d30930-33a7-4f9c-bf4b-9d0d51c53d44"
      unitRef="usd">0</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="i66702e11ddcd4d94b4f6a53b4231f09f_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTEtMi0xLTEtMA_a8f49328-f491-49af-b3db-084a0b8e824a"
      unitRef="usd">0</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="ice9f1dfc8f83445b9b89ebcebe763f1a_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTEtNC0xLTEtMA_9d3dac9e-c7ec-4c20-8b57-38e51bdce998"
      unitRef="usd">0</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:NetIncomeLoss
      contextRef="i66702e11ddcd4d94b4f6a53b4231f09f_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTItMi0xLTEtMA_3e787878-a8cf-459b-878a-96a326fcb54d"
      unitRef="usd">0</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="ice9f1dfc8f83445b9b89ebcebe763f1a_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTItNC0xLTEtMA_8d0e7ecb-a071-4753-aaf5-57143645e9e9"
      unitRef="usd">0</us-gaap:NetIncomeLoss>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ibd9038c5b623433f87f5b5ece6980092_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTctMi0xLTEtMA_5ad4d4a3-3747-4490-be26-d17200dc78ba"
      unitRef="usd">-24000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i74e3224ed0df4d7b844d1e04f9657708_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTctNC0xLTEtMA_1ce87d44-af95-4540-9a00-5a46dedb0c05"
      unitRef="usd">158000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="iba01b07f6b98472d83708a5396a4df3b_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTgtMi0xLTEtMA_bf66088e-1d3b-4957-a570-a5289de4404c"
      unitRef="usd">-190000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i67a805bd27be4c1fb6e4f9f773fd62d8_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMTgtNC0xLTEtMA_c89c7466-0bac-4eee-b819-d49151b8b0db"
      unitRef="usd">101000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments
      contextRef="i7702c711db32401d9e72b707815b70d5_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjAtMi0xLTEtMA_3c330f32-1c31-46fd-91d1-f58f085ffbb4"
      unitRef="usd">-214000000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments>
    <us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments
      contextRef="if763cdb48cee4124a55a518d0549ffcd_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjAtNC0xLTEtMA_d57b4714-bd76-4698-9d86-80f2d04106e5"
      unitRef="usd">259000000</us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="i7702c711db32401d9e72b707815b70d5_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjEtMi0xLTEtMA_b873212d-06af-4c07-b8de-cc1f81014f5b"
      unitRef="usd">-45000000</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="if763cdb48cee4124a55a518d0549ffcd_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjEtNC0xLTEtMA_ba22bdfa-bd85-4572-b913-49e0a91fae9e"
      unitRef="usd">57000000</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:NetIncomeLoss
      contextRef="i7702c711db32401d9e72b707815b70d5_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjItMi0xLTEtMA_7963e816-9d33-4bf2-8372-bfd9d2f0eb59"
      unitRef="usd">-169000000</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="if763cdb48cee4124a55a518d0549ffcd_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjItNC0xLTEtMA_675fecd3-ba51-4f7b-80a8-6aa4e419c1b4"
      unitRef="usd">202000000</us-gaap:NetIncomeLoss>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="ifd7b5626cee240a48eb61b6441030918_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjQtMi0xLTEtMA_6459277a-8a0d-4e6b-8dc6-5b989f817b46"
      unitRef="usd">0</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="iee30caa26817491b92bd2d46a5a5214d_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjQtNC0xLTEtMA_1b1b700e-f1bf-418d-b83a-ed22898ab3dd"
      unitRef="usd">33000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="ifd7b5626cee240a48eb61b6441030918_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjUtMi0xLTEtMA_c1d26343-d47f-4404-b421-5bf70f589564"
      unitRef="usd">0</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:IncomeTaxExpenseBenefit
      contextRef="iee30caa26817491b92bd2d46a5a5214d_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjUtNC0xLTEtMA_2d5588a7-4dbc-46ec-b526-c50854fe09a1"
      unitRef="usd">7000000</us-gaap:IncomeTaxExpenseBenefit>
    <us-gaap:NetIncomeLoss
      contextRef="ifd7b5626cee240a48eb61b6441030918_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjYtMi0xLTEtMA_d753e9d1-37ec-4fb5-b9ad-0989391c7830"
      unitRef="usd">0</us-gaap:NetIncomeLoss>
    <us-gaap:NetIncomeLoss
      contextRef="iee30caa26817491b92bd2d46a5a5214d_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82MS9mcmFnOjZkNjUwYzQxNGU3MTQ4ZTZhYTBhOTE3ZmE4YzY3ZDI3L3RhYmxlOjExNzQ5NTg3YmFmYTRiN2FiYjQwNjE2Yjk4YTkwMmM3L3RhYmxlcmFuZ2U6MTE3NDk1ODdiYWZhNGI3YWJiNDA2MTZiOThhOTAyYzdfMjYtNC0xLTEtMA_1c44861a-2f50-4a04-8cd6-38cb9ee73296"
      unitRef="usd">26000000</us-gaap:NetIncomeLoss>
    <us-gaap:FairValueDisclosuresTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RleHRyZWdpb246MDBlOGE3MGFkYTlmNDA5Yzk4NTQ5YWNkM2NlMjA2NjBfNDM3NQ_1d2d0889-0ae0-44ad-9e5f-50b70e7d32f6">Fair value measurement&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;To estimate the fair value of our financial assets and liabilities, we use valuation approaches within a hierarchy that maximizes the use of observable inputs and minimizes the use of unobservable inputs by requiring that observable inputs be used when available. Observable inputs are inputs that market participants would use in pricing an asset or liability based on market data obtained from sources independent of the Company. Unobservable inputs are inputs that reflect the Company&#x2019;s assumptions about the inputs that market participants would use in pricing an asset or liability and are developed based on the best information available in the circumstances. The fair value hierarchy is divided into three levels based on the source of inputs as follows:&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:1pt;text-align:center;text-indent:22.5pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:98.391%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:6.180%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:2.177%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:89.243%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Level&#160;1&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Valuations based on unadjusted quoted prices in active markets for identical assets or liabilities that the Company has the ability to access&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Level&#160;2&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Valuations for which all significant inputs are observable either directly or indirectly&#x2014;other than Level 1 inputs&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Level&#160;3&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Valuations based on inputs that are unobservable and significant to the overall fair value measurement&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The availability of observable inputs can vary among different types of financial assets and liabilities. To the extent that the valuation is based on models or inputs that are less observable or unobservable in the market, the determination of fair value requires more judgment. In certain cases, the inputs used for measuring fair value may fall into different levels of the fair value hierarchy. In such cases, for financial statement disclosure purposes, the level in the fair value hierarchy within which the fair value measurement is categorized is based on the lowest level of input used that is significant to the overall fair value measurement.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The fair values of each major class of the Company&#x2019;s financial assets and liabilities measured at fair value on a recurring basis were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:40.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.788%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.788%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.788%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.796%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr style="height:12pt"&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Quoted&#160;prices in&lt;br/&gt;active&#160;markets&#160;for&lt;br/&gt;identical assets&lt;br/&gt;(Level 1)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Significant&lt;br/&gt;other&#160;observable&lt;br/&gt;inputs&lt;br/&gt;(Level 2)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Significant&lt;br/&gt;unobservable&lt;br/&gt;inputs&lt;br/&gt;(Level 3)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr style="height:12pt"&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr style="height:12pt"&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair value measurement as of September 30, 2021, using:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Total&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"&gt;Assets:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Available-for-sale securities:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;51&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;51&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury bills&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,900&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,900&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Money market mutual funds&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;8,323&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;8,323&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other short-term interest-bearing securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Equity securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;608&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;257&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;865&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Derivatives:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;127&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;127&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;119&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;119&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Interest rate swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;29&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;29&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;12,882&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;276&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;257&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;13,415&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"&gt;Liabilities:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Derivatives:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;54&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;54&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;360&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;360&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Interest rate swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;105&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;105&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;div style="padding-left:15.75pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Contingent consideration obligations&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;35&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;35&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total liabilities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;519&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;35&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;554&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:40.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.788%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.788%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.788%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.796%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr style="height:11pt"&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Quoted&#160;prices in&lt;br/&gt;active&#160;markets&#160;for&lt;br/&gt;identical assets&lt;br/&gt;(Level 1)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Significant&lt;br/&gt;other observable&lt;br/&gt;inputs&lt;br/&gt;(Level 2)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Significant&lt;br/&gt;unobservable&lt;br/&gt;inputs&lt;br/&gt;(Level 3)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr style="height:12pt"&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair value measurement as of December 31, 2020, using:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Total&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"&gt;Assets:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Available-for-sale securities:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;130&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;130&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury bills&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,948&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,948&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Money market mutual funds&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,765&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,765&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other short-term interest-bearing securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Equity securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;477&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;477&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Derivatives:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;28&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;28&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;255&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;255&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Interest rate swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;66&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;66&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;10,320&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;351&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;10,671&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"&gt;Liabilities:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Derivatives:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;237&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;237&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;318&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;318&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Interest rate swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;15&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;15&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;div style="padding-left:15.75pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Contingent consideration obligations&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;33&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;33&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total liabilities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;570&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;33&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;603&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="text-align:justify"&gt;&lt;span&gt;&lt;br/&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Interest-bearing and equity securities&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The fair values of our U.S. Treasury securities, money market mutual funds and equity investments in publicly traded securities are based on quoted market prices in active markets, with no valuation adjustment. The fair value of equity securities without readily determinable fair values are initially valued at the transaction price and subsequently valued based upon a combination of entity-specific financial information and publicly available market information for similar companies that have actively traded equity securities.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Derivatives&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;All of our foreign currency forward derivative contracts have maturities of three years or less, and all are with counterparties that have minimum credit ratings of A&#x2013; or equivalent by Standard &amp;amp; Poor&#x2019;s Financial Services LLC (S&amp;amp;P), Moody&#x2019;s Investors Service, Inc. (Moody&#x2019;s) or Fitch Ratings, Inc. (Fitch). We estimate the fair values of these contracts by taking into consideration valuations obtained from a third-party valuation service that uses an income-based industry-standard valuation model for which all significant inputs are observable either directly or indirectly. These inputs include foreign currency exchange rates, LIBOR, swap rates and obligor credit default swap rates. In addition, inputs for our foreign currency option contracts include implied volatility measures. These inputs, when applicable, are at commonly quoted intervals. See Note 13, Derivative instruments.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Our cross-currency swap contracts are with counterparties that have minimum credit ratings of A&#x2013; or equivalent by S&amp;amp;P, Moody&#x2019;s or Fitch. We estimate the fair values of these contracts by taking into consideration valuations obtained from a third-party valuation service that uses an income-based industry-standard valuation model for which all significant inputs are observable either directly or indirectly. These inputs include foreign currency exchange rates, LIBOR, swap rates, obligor credit default swap rates and cross-currency-basis swap spreads. See Note 13, Derivative instruments.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Our interest rate swap contracts are with counterparties that have minimum credit ratings of A&#x2013; or equivalent by S&amp;amp;P, Moody&#x2019;s or Fitch. We estimate the fair values of these contracts by using an income-based industry-standard valuation model for which all significant inputs are observable either directly or indirectly. These inputs include LIBOR, swap rates and obligor credit default swap rates. See Note 13, Derivative instruments.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;During the three and nine months ended September 30, 2021 and 2020, there were no material remeasurements to the fair values of assets and liabilities that are not measured at fair value on a recurring basis.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Summary of the fair values of other financial instruments&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Cash equivalents&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The fair values of cash equivalents approximate their carrying values due to the short-term nature of such financial instruments.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Borrowings&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;We estimated the fair values of our borrowings by using Level 2 inputs. As of September 30, 2021 and December 31, 2020, the aggregate fair values of our borrowings were $42.2 billion and $39.4 billion, respectively, and the carrying values were $37.6 billion and $33.0 billion, respectively.&lt;/span&gt;&lt;/div&gt;</us-gaap:FairValueDisclosuresTextBlock>
    <us-gaap:ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RleHRyZWdpb246MDBlOGE3MGFkYTlmNDA5Yzk4NTQ5YWNkM2NlMjA2NjBfNDM2Mw_f3df4040-9ca7-4404-b067-058aa25dfcbd">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The fair values of each major class of the Company&#x2019;s financial assets and liabilities measured at fair value on a recurring basis were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:40.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.788%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.788%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.788%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.796%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr style="height:12pt"&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Quoted&#160;prices in&lt;br/&gt;active&#160;markets&#160;for&lt;br/&gt;identical assets&lt;br/&gt;(Level 1)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Significant&lt;br/&gt;other&#160;observable&lt;br/&gt;inputs&lt;br/&gt;(Level 2)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Significant&lt;br/&gt;unobservable&lt;br/&gt;inputs&lt;br/&gt;(Level 3)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr style="height:12pt"&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr style="height:12pt"&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair value measurement as of September 30, 2021, using:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Total&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"&gt;Assets:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Available-for-sale securities:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;51&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;51&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury bills&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,900&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3,900&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Money market mutual funds&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;8,323&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;8,323&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other short-term interest-bearing securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Equity securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;608&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;257&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;865&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Derivatives:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;127&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;127&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;119&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;119&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Interest rate swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;29&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;29&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;12,882&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;276&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;257&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;13,415&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"&gt;Liabilities:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Derivatives:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;54&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;54&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;360&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;360&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Interest rate swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;105&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;105&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;div style="padding-left:15.75pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Contingent consideration obligations&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;35&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;35&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total liabilities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;519&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;35&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;554&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:40.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.788%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.788%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.788%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:12.796%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr style="height:11pt"&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Quoted&#160;prices in&lt;br/&gt;active&#160;markets&#160;for&lt;br/&gt;identical assets&lt;br/&gt;(Level 1)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Significant&lt;br/&gt;other observable&lt;br/&gt;inputs&lt;br/&gt;(Level 2)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Significant&lt;br/&gt;unobservable&lt;br/&gt;inputs&lt;br/&gt;(Level 3)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr style="height:12pt"&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair value measurement as of December 31, 2020, using:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Total&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"&gt;Assets:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Available-for-sale securities:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;130&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;130&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;U.S. Treasury bills&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,948&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,948&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Money market mutual funds&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,765&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4,765&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other short-term interest-bearing securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Equity securities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;477&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;477&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Derivatives:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;28&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;28&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;255&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;255&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Interest rate swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;66&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;66&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;10,320&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;351&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;10,671&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr style="height:15pt"&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%"&gt;Liabilities:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Derivatives:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;237&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;237&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;318&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;318&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Interest rate swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;15&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;15&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;div style="padding-left:15.75pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Contingent consideration obligations&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;33&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;33&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total liabilities&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;570&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;33&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;603&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;</us-gaap:ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i826a29ed0f7a402ea34f70df227b7521_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNS0yLTEtMS0w_0ae4db44-b77a-42ec-98b5-f76f1b841f49"
      unitRef="usd">51000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i7d76b8e7f94f45cc9e548d9fb2040f2d_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNS00LTEtMS0w_bf3a5ed4-e6e1-4162-ade8-6611d3e23f98"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i37882f19b0784eccafabfe836dc51f25_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNS02LTEtMS0w_03614a8d-9dee-49a6-a326-0cfd8462863c"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i0523566bb4bd4ac7a167861d41b07412_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNS04LTEtMS0w_a31516d1-deed-41cf-aebb-84ef61cfa48f"
      unitRef="usd">51000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="if0fb1e0d683243249078c344db9e3287_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNi0yLTEtMS0w_53a06fb1-5476-4225-9a13-15844c71dcd9"
      unitRef="usd">3900000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="ie0b4aff0ec6c41e18c08f8a27f8d35d6_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNi00LTEtMS0w_19607e61-e7e7-446a-8679-7b8206023633"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i9bf07042070142818b2dcc65da76d130_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNi02LTEtMS0w_5d59ecd2-b02a-4afb-9449-f841d1a83d26"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i8db023e72bf0457098764c83dfe06255_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfNi04LTEtMS0w_716218a1-eb14-4f13-b597-966e66925061"
      unitRef="usd">3900000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i1b770f2bad0a458bb80d6080d416e653_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTYtMi0xLTEtMA_7cd2d0ba-250a-48dc-a354-682cbf826b16"
      unitRef="usd">8323000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i1b4470fbc2904831b9b368445e211ea4_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTYtNC0xLTEtMA_492e5018-73c3-4709-8d5e-995411acce56"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i33c195572dca4fbf824c6e47b083ab07_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTYtNi0xLTEtMA_147fdef7-cc0b-4880-8cfa-c209de6bcb9f"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i3022e170e868460588b8873ad8b918de_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTYtOC0xLTEtMA_978b58d1-e6e8-43e7-91c0-f32de270bc2c"
      unitRef="usd">8323000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i63f7d63505ec40e78832bd42bf718996_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTctMi0xLTEtMA_0cd1fde1-ea20-4700-9586-d54574da180c"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i25e32e59bf21440087114ea6114b506b_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTctNC0xLTEtMA_e5f3a0b5-2278-4961-afcd-5640bda57b33"
      unitRef="usd">1000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="iab7f53e834574888ab2bc9ca340df3f0_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTctNi0xLTEtMA_6827b8cc-f2db-4f58-9904-47b14ac68511"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="ic7d3b5bd8e574e95949520f4cff15af1_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTctOC0xLTEtMA_a46a27b3-b6a8-4139-a050-df58bcf932d2"
      unitRef="usd">1000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:EquitySecuritiesFvNi
      contextRef="ib2b89ed4eb094c5f966961837399b7ca_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTgtMi0xLTEtMA_609b626b-c65c-460c-953a-0143d7fd76af"
      unitRef="usd">608000000</us-gaap:EquitySecuritiesFvNi>
    <us-gaap:EquitySecuritiesFvNi
      contextRef="i668050cd480a44d59980ffd4209aa796_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTgtNC0xLTEtMA_babedd22-518f-4564-a91e-a6fd993be8da"
      unitRef="usd">0</us-gaap:EquitySecuritiesFvNi>
    <us-gaap:EquitySecuritiesFvNi
      contextRef="i9d7900fb43d041f4bbfa2d693a513c61_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTgtNi0xLTEtMA_ec087135-e34f-49ff-944a-a11e81ed59ea"
      unitRef="usd">257000000</us-gaap:EquitySecuritiesFvNi>
    <us-gaap:EquitySecuritiesFvNi
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMTgtOC0xLTEtMA_6ab0345a-95e2-4d39-8fca-69d7769a6148"
      unitRef="usd">865000000</us-gaap:EquitySecuritiesFvNi>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="i222681c138f44598b25427e0b8ccae76_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjAtMi0xLTEtMA_228a3774-299e-42f9-b89a-f07b4287cde5"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="idb72f426587a4ec5befa804534b12722_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjAtNC0xLTEtMA_0f833fe8-a1f9-4fed-b397-4725fe1ef710"
      unitRef="usd">127000000</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="i25541eb9d6c34199be9b71a30ee0401d_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjAtNi0xLTEtMA_deba8c70-113a-4a75-9196-89103644dc65"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="i9e90f12e90a449639d72687889f2e95a_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjAtOC0xLTEtMA_bc124ce4-7949-4bfc-9287-88ff06dc8a8b"
      unitRef="usd">127000000</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="ied5df9df96c04c2ba41897fd892ef61f_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjEtMi0xLTEtMA_9016dcec-bed8-44a5-a6ff-425138db7cf5"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="id8e22719623e4f98b17f615c76dbb3bd_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjEtNC0xLTEtMA_190a600f-66aa-4684-9b8c-763d1853df98"
      unitRef="usd">119000000</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="icef3bcd64f2c4ba38b4e195178b28e0a_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjEtNi0xLTEtMA_04d3f672-8d0f-4a92-996f-df3f950a52de"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="i06db08463971480086be884f8fb2f0d5_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjEtOC0xLTEtMA_6282b28d-a667-40b3-af03-ce6a8b687ee2"
      unitRef="usd">119000000</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:InterestRateFairValueHedgeAssetAtFairValue
      contextRef="i891c6c71b8e7435ea6af4ad541a9f170_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjItMi0xLTEtMA_89b2ac78-8987-4cab-aa18-5b6a819b54ff"
      unitRef="usd">0</us-gaap:InterestRateFairValueHedgeAssetAtFairValue>
    <us-gaap:InterestRateFairValueHedgeAssetAtFairValue
      contextRef="i905b99ada59844fe9615f05632d936ba_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjItNC0xLTEtMA_e8ac2fb7-1e9f-4b4a-81af-a7058e029037"
      unitRef="usd">29000000</us-gaap:InterestRateFairValueHedgeAssetAtFairValue>
    <us-gaap:InterestRateFairValueHedgeAssetAtFairValue
      contextRef="id43e4d99182d4a8fa11017c14d8cff33_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjItNi0xLTEtMA_1f425a62-c0bc-416c-a2ee-82cf0c13bfad"
      unitRef="usd">0</us-gaap:InterestRateFairValueHedgeAssetAtFairValue>
    <us-gaap:InterestRateFairValueHedgeAssetAtFairValue
      contextRef="i0345015d43454b10b538d7fe7b901fa5_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjItOC0xLTEtMA_b7605d40-4c86-4a68-9d96-c3cc20245acc"
      unitRef="usd">29000000</us-gaap:InterestRateFairValueHedgeAssetAtFairValue>
    <us-gaap:AssetsFairValueDisclosure
      contextRef="ib2b89ed4eb094c5f966961837399b7ca_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjQtMi0xLTEtMA_1bcf9c35-e996-4bc6-b194-d577b731d7d4"
      unitRef="usd">12882000000</us-gaap:AssetsFairValueDisclosure>
    <us-gaap:AssetsFairValueDisclosure
      contextRef="i668050cd480a44d59980ffd4209aa796_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjQtNC0xLTEtMA_4fac71a4-16e6-4ae1-8e37-094b83358be6"
      unitRef="usd">276000000</us-gaap:AssetsFairValueDisclosure>
    <us-gaap:AssetsFairValueDisclosure
      contextRef="i9d7900fb43d041f4bbfa2d693a513c61_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjQtNi0xLTEtMA_7dabe0a6-64c7-4e7b-8d77-9bdd39a924db"
      unitRef="usd">257000000</us-gaap:AssetsFairValueDisclosure>
    <us-gaap:AssetsFairValueDisclosure
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjQtOC0xLTEtMA_301d042a-2d34-4886-b27c-709a6dd8dfdd"
      unitRef="usd">13415000000</us-gaap:AssetsFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="i222681c138f44598b25427e0b8ccae76_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjgtMi0xLTEtMA_650e4952-ed14-4db5-9bb2-f3d5616b39bc"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="idb72f426587a4ec5befa804534b12722_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjgtNC0xLTEtMA_504ee7a0-bed6-4f33-8615-c1c5f62b6a7b"
      unitRef="usd">54000000</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="i25541eb9d6c34199be9b71a30ee0401d_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjgtNi0xLTEtMA_fa34038a-5b57-43ca-91aa-7376a85731ea"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="i9e90f12e90a449639d72687889f2e95a_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjgtOC0xLTEtMA_06250bf9-8f7c-4369-9084-f83071b00718"
      unitRef="usd">54000000</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="ied5df9df96c04c2ba41897fd892ef61f_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjktMi0xLTEtMA_2bb59231-a5c9-4aed-8f96-5feaf6d557c8"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="id8e22719623e4f98b17f615c76dbb3bd_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjktNC0xLTEtMA_dab2ed6a-7543-4874-86f6-f7d752c78498"
      unitRef="usd">360000000</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="icef3bcd64f2c4ba38b4e195178b28e0a_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjktNi0xLTEtMA_ef1ad914-1994-4cf7-a58f-8d83c0d359e6"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="i06db08463971480086be884f8fb2f0d5_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMjktOC0xLTEtMA_e2c4bd84-1ac1-4a43-b1a9-7f3d37093cf1"
      unitRef="usd">360000000</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue
      contextRef="i891c6c71b8e7435ea6af4ad541a9f170_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzAtMi0xLTEtMA_763cb849-3dbd-4099-86b9-6bea38e8907f"
      unitRef="usd">0</us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue>
    <us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue
      contextRef="i905b99ada59844fe9615f05632d936ba_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzAtNC0xLTEtMA_f648e1b8-e45e-4bae-925f-2c67b1f84cf8"
      unitRef="usd">105000000</us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue>
    <us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue
      contextRef="id43e4d99182d4a8fa11017c14d8cff33_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzAtNi0xLTEtMA_344e3e32-a4b2-4d13-9f69-06c880b35fe4"
      unitRef="usd">0</us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue>
    <us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue
      contextRef="i0345015d43454b10b538d7fe7b901fa5_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzAtOC0xLTEtMA_3926d83b-fa0c-4fac-b0cf-c6f5898dec09"
      unitRef="usd">105000000</us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue>
    <us-gaap:BusinessCombinationContingentConsiderationLiability
      contextRef="ib2b89ed4eb094c5f966961837399b7ca_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzEtMi0xLTEtMA_4b0392d9-956a-42a4-bfce-a5bb13f4e695"
      unitRef="usd">0</us-gaap:BusinessCombinationContingentConsiderationLiability>
    <us-gaap:BusinessCombinationContingentConsiderationLiability
      contextRef="i668050cd480a44d59980ffd4209aa796_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzEtNC0xLTEtMA_346ba1db-95b5-4c3b-8e28-8f4da7ae4183"
      unitRef="usd">0</us-gaap:BusinessCombinationContingentConsiderationLiability>
    <us-gaap:BusinessCombinationContingentConsiderationLiability
      contextRef="i9d7900fb43d041f4bbfa2d693a513c61_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzEtNi0xLTEtMA_8c2b4425-18da-4b95-a225-18c142c269df"
      unitRef="usd">35000000</us-gaap:BusinessCombinationContingentConsiderationLiability>
    <us-gaap:BusinessCombinationContingentConsiderationLiability
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzEtOC0xLTEtMA_cecc1e26-dc8a-450a-963c-209b9e58c97c"
      unitRef="usd">35000000</us-gaap:BusinessCombinationContingentConsiderationLiability>
    <us-gaap:LiabilitiesFairValueDisclosure
      contextRef="ib2b89ed4eb094c5f966961837399b7ca_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzItMi0xLTEtMA_9a60ce38-b702-4595-9b4b-ba0e3bbe7347"
      unitRef="usd">0</us-gaap:LiabilitiesFairValueDisclosure>
    <us-gaap:LiabilitiesFairValueDisclosure
      contextRef="i668050cd480a44d59980ffd4209aa796_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzItNC0xLTEtMA_016c4ceb-8e3a-4d69-877b-42a424e68587"
      unitRef="usd">519000000</us-gaap:LiabilitiesFairValueDisclosure>
    <us-gaap:LiabilitiesFairValueDisclosure
      contextRef="i9d7900fb43d041f4bbfa2d693a513c61_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzItNi0xLTEtMA_6a092a82-f49b-4160-8396-9dcb205ad941"
      unitRef="usd">35000000</us-gaap:LiabilitiesFairValueDisclosure>
    <us-gaap:LiabilitiesFairValueDisclosure
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjBhNWRjMTJkZmNlMjQ3MWE4MjZiMDcwYzNmODczNGM3L3RhYmxlcmFuZ2U6MGE1ZGMxMmRmY2UyNDcxYTgyNmIwNzBjM2Y4NzM0YzdfMzItOC0xLTEtMA_0d6c183a-e0aa-4966-9a63-626b9443da55"
      unitRef="usd">554000000</us-gaap:LiabilitiesFairValueDisclosure>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i7d9048c66277472987f2e5c853ea849f_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNS0yLTEtMS0w_639f1da8-174e-4967-b188-6d2a0fd06280"
      unitRef="usd">130000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="if46f80f8f61a471bbd2f2cd5ffc18024_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNS00LTEtMS0w_1be347dd-cdfd-4f2d-b080-a79a27d56814"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="ifb485de2ab374debabfd24e341e4d676_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNS02LTEtMS0w_034d9586-40e6-4e47-a070-7179b59295cc"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i507488fbf87d4c6296eb13e3e0006fbf_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNS04LTEtMS0w_2d4bb2c0-c68c-4cee-881b-f7389b2705a9"
      unitRef="usd">130000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="ibbe73c36ec8a41f991d38edd0c64bb47_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNi0yLTEtMS0w_677ba725-5cdd-44f1-907a-22eba04972a7"
      unitRef="usd">4948000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="ib8fabc2c97464ca0bbc9f7eb0a1fce39_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNi00LTEtMS0w_079dc274-b2de-4ee0-87bc-023337926526"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i9c8094c8dc344979833ee0c0a4184c0f_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNi02LTEtMS0w_c6a6dd02-d242-4c53-ae67-850824359a3b"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i8ba30f0c09fc4bfd9fe36a47079d2854_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfNi04LTEtMS0w_88c85d93-1165-4043-af22-c86ec2abba73"
      unitRef="usd">4948000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="ic99616af30c6481c95e52063cc58aab7_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTYtMi0xLTEtMA_759fac78-42f8-442d-82c7-bf69792effd5"
      unitRef="usd">4765000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="id4322deb32b242dc9dc95226e1f24e7a_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTYtNC0xLTEtMA_342cb528-03ad-492f-a378-d55784864ee8"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i5720d28c85fd42cf9bf79344cb93f92e_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTYtNi0xLTEtMA_9378da22-c753-4cc7-86b0-b3edd514fff9"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i54f838959ac943e79d09dcf9e6faada4_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTYtOC0xLTEtMA_75f58e4f-9887-4156-b27c-973d35211fc3"
      unitRef="usd">4765000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i2dc6f4e8be7843d6aaca2adf5f4c6884_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTctMi0xLTEtMA_c896e08a-7b0b-46c6-b2be-64a1d15b0324"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="id158e2e208fe42f6babb0bf2b8d9c0fd_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTctNC0xLTEtMA_80b5f858-6df2-43d4-9c72-52e43dfcf8b7"
      unitRef="usd">2000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i0d6271a8a04b419399a0b38f81c5198f_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTctNi0xLTEtMA_d7978717-9463-4900-ae8b-d4a09a168d1c"
      unitRef="usd">0</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:AvailableForSaleSecuritiesDebtSecurities
      contextRef="i84edbdc908bc4493a769cf963ac32f28_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTctOC0xLTEtMA_2eb928e9-e2a3-4fba-bd6c-9cf44e44f851"
      unitRef="usd">2000000</us-gaap:AvailableForSaleSecuritiesDebtSecurities>
    <us-gaap:EquitySecuritiesFvNi
      contextRef="ia0271b62203b4afbbefbea6461a32a14_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTgtMi0xLTEtMA_6c1450cb-3551-410d-809a-0032386720d5"
      unitRef="usd">477000000</us-gaap:EquitySecuritiesFvNi>
    <us-gaap:EquitySecuritiesFvNi
      contextRef="ie0f44542e8c740659e299accf3ca4908_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTgtNC0xLTEtMA_84c83ddc-7e61-43b0-8e1d-faedb1705c4d"
      unitRef="usd">0</us-gaap:EquitySecuritiesFvNi>
    <us-gaap:EquitySecuritiesFvNi
      contextRef="ie342e06932cb4eb09ce0c2794ac21c83_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTgtNi0xLTEtMA_c1024950-6d85-479e-b929-8ca521110b06"
      unitRef="usd">0</us-gaap:EquitySecuritiesFvNi>
    <us-gaap:EquitySecuritiesFvNi
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMTgtOC0xLTEtMA_8d4b85cd-0ad3-443d-aa6d-d782e2e6c4f1"
      unitRef="usd">477000000</us-gaap:EquitySecuritiesFvNi>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="i54877d697b024c418e4690308061e7d5_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjAtMi0xLTEtMA_90d0a641-c7bf-4577-844f-21cd20b6c63f"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="i454c26ac3d9f4433aebd4f00ce56ef66_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjAtNC0xLTEtMA_8d9d4fe9-dff5-4e46-84d5-6016a7b586f9"
      unitRef="usd">28000000</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="i367c35eaeba64e7dacfc5f757575d411_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjAtNi0xLTEtMA_142c08cd-efb4-4bfa-98b4-c7609f27904a"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="i5d128d2186654d918c38f7fc1d9b358c_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjAtOC0xLTEtMA_b0256ec6-1c82-4b7c-83a9-9673a7fcbf9b"
      unitRef="usd">28000000</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="i17fe29849f934c778d329dd2ac540b0f_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjEtMi0xLTEtMA_4f80c360-dffa-486b-99eb-95e1a56317cb"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="i1f484e76b00143c49d1ffb0c04e1aa31_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjEtNC0xLTEtMA_72c8a9f4-9705-40aa-9378-d860bdab0a73"
      unitRef="usd">255000000</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="i62f678821295404c8ddc6c8b0b67d7e2_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjEtNi0xLTEtMA_2e4389e0-ee76-4caa-addc-ea9706776ca6"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractAssetFairValueDisclosure
      contextRef="i2cc8acfb8b1c4f2eaf54f3edfd2fca61_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjEtOC0xLTEtMA_7d2aef1a-2078-4d3b-94ff-f7b2c513f440"
      unitRef="usd">255000000</us-gaap:ForeignCurrencyContractAssetFairValueDisclosure>
    <us-gaap:InterestRateFairValueHedgeAssetAtFairValue
      contextRef="i84e77eb97532442da0b8735429da4ecc_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjItMi0xLTEtMA_b43d91c0-43cc-4465-a0b7-d69540f77cec"
      unitRef="usd">0</us-gaap:InterestRateFairValueHedgeAssetAtFairValue>
    <us-gaap:InterestRateFairValueHedgeAssetAtFairValue
      contextRef="ifc9c4b5754af40009253488e23ef0207_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjItNC0xLTEtMA_0021afd7-192c-4bc8-99b6-1bf0d1f83a35"
      unitRef="usd">66000000</us-gaap:InterestRateFairValueHedgeAssetAtFairValue>
    <us-gaap:InterestRateFairValueHedgeAssetAtFairValue
      contextRef="i69ee586072574a02b0f1bc1f4029919c_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjItNi0xLTEtMA_0a10c265-52c9-43f1-94dc-fd14f490bdbe"
      unitRef="usd">0</us-gaap:InterestRateFairValueHedgeAssetAtFairValue>
    <us-gaap:InterestRateFairValueHedgeAssetAtFairValue
      contextRef="i1197e68d9d604430b8ce3c78e941f5f2_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjItOC0xLTEtMA_43abfe45-d15a-4c6f-9333-d5e7698ddfdd"
      unitRef="usd">66000000</us-gaap:InterestRateFairValueHedgeAssetAtFairValue>
    <us-gaap:AssetsFairValueDisclosure
      contextRef="ia0271b62203b4afbbefbea6461a32a14_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjMtMi0xLTEtMA_59c95555-310a-4ccb-9d24-efce0a659d90"
      unitRef="usd">10320000000</us-gaap:AssetsFairValueDisclosure>
    <us-gaap:AssetsFairValueDisclosure
      contextRef="ie0f44542e8c740659e299accf3ca4908_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjMtNC0xLTEtMA_608d17ea-94e6-4f64-8eba-13f6910ca9b1"
      unitRef="usd">351000000</us-gaap:AssetsFairValueDisclosure>
    <us-gaap:AssetsFairValueDisclosure
      contextRef="ie342e06932cb4eb09ce0c2794ac21c83_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjMtNi0xLTEtMA_84e551e2-afa7-4184-a7aa-989d3494451b"
      unitRef="usd">0</us-gaap:AssetsFairValueDisclosure>
    <us-gaap:AssetsFairValueDisclosure
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjMtOC0xLTEtMA_64a18593-2ae1-45d1-ba22-760da12c9a51"
      unitRef="usd">10671000000</us-gaap:AssetsFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="i54877d697b024c418e4690308061e7d5_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjctMi0xLTEtMA_6c0da948-7445-4e7d-9ec9-0482a2c9f3fa"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="i454c26ac3d9f4433aebd4f00ce56ef66_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjctNC0xLTEtMA_ad416f9f-81cc-485d-b74b-f89ef2f360b5"
      unitRef="usd">237000000</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="i367c35eaeba64e7dacfc5f757575d411_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjctNi0xLTEtMA_11c6488f-08f7-47c6-b457-f7acab80e55e"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="i5d128d2186654d918c38f7fc1d9b358c_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjctOC0xLTEtMA_4efa764c-fc5d-46fc-b90c-80e6bf3a0ad9"
      unitRef="usd">237000000</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="i17fe29849f934c778d329dd2ac540b0f_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjgtMi0xLTEtMA_13fc96ca-eb84-4226-b78b-60c8c69463cd"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="i1f484e76b00143c49d1ffb0c04e1aa31_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjgtNC0xLTEtMA_5804231a-2449-4534-bc3b-ea433066852d"
      unitRef="usd">318000000</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="i62f678821295404c8ddc6c8b0b67d7e2_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjgtNi0xLTEtMA_f3da9320-c120-4222-81c8-e9d69d3c65fb"
      unitRef="usd">0</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure
      contextRef="i2cc8acfb8b1c4f2eaf54f3edfd2fca61_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjgtOC0xLTEtMA_2a7387b6-5e56-4efb-879d-247615dad3d3"
      unitRef="usd">318000000</us-gaap:ForeignCurrencyContractsLiabilityFairValueDisclosure>
    <us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue
      contextRef="i84e77eb97532442da0b8735429da4ecc_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjktMi0xLTEtMA_84b8c600-dd63-4b89-a795-37e7d456fb0f"
      unitRef="usd">0</us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue>
    <us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue
      contextRef="ifc9c4b5754af40009253488e23ef0207_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjktNC0xLTEtMA_dc9cfc59-ab6e-42af-b6af-9468b1aa4346"
      unitRef="usd">15000000</us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue>
    <us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue
      contextRef="i69ee586072574a02b0f1bc1f4029919c_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjktNi0xLTEtMA_18cae5d5-eb1a-4933-a6d5-895e64fbe594"
      unitRef="usd">0</us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue>
    <us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue
      contextRef="i1197e68d9d604430b8ce3c78e941f5f2_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMjktOC0xLTEtMA_11355877-863a-4205-ab07-1724868a3908"
      unitRef="usd">15000000</us-gaap:InterestRateFairValueHedgeLiabilityAtFairValue>
    <us-gaap:BusinessCombinationContingentConsiderationLiability
      contextRef="ia0271b62203b4afbbefbea6461a32a14_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzAtMi0xLTEtMA_7a736c1f-94b9-43cd-8a7e-4bc8a51fed6d"
      unitRef="usd">0</us-gaap:BusinessCombinationContingentConsiderationLiability>
    <us-gaap:BusinessCombinationContingentConsiderationLiability
      contextRef="ie0f44542e8c740659e299accf3ca4908_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzAtNC0xLTEtMA_6afb56e3-5179-46a7-96c0-bd58363dedd4"
      unitRef="usd">0</us-gaap:BusinessCombinationContingentConsiderationLiability>
    <us-gaap:BusinessCombinationContingentConsiderationLiability
      contextRef="ie342e06932cb4eb09ce0c2794ac21c83_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzAtNi0xLTEtMA_53fc1f53-491e-4dc8-9691-34e87bd1047e"
      unitRef="usd">33000000</us-gaap:BusinessCombinationContingentConsiderationLiability>
    <us-gaap:BusinessCombinationContingentConsiderationLiability
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzAtOC0xLTEtMA_238d6171-1b6b-4fb6-9777-6b5d2e072a40"
      unitRef="usd">33000000</us-gaap:BusinessCombinationContingentConsiderationLiability>
    <us-gaap:LiabilitiesFairValueDisclosure
      contextRef="ia0271b62203b4afbbefbea6461a32a14_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzEtMi0xLTEtMA_50a7a671-1604-41b2-8de0-accd5ce4337f"
      unitRef="usd">0</us-gaap:LiabilitiesFairValueDisclosure>
    <us-gaap:LiabilitiesFairValueDisclosure
      contextRef="ie0f44542e8c740659e299accf3ca4908_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzEtNC0xLTEtMA_bbe66dad-488e-42cd-9ef8-304c1f64a606"
      unitRef="usd">570000000</us-gaap:LiabilitiesFairValueDisclosure>
    <us-gaap:LiabilitiesFairValueDisclosure
      contextRef="ie342e06932cb4eb09ce0c2794ac21c83_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzEtNi0xLTEtMA_0e117619-c89e-459e-8729-90e6bbebc64f"
      unitRef="usd">33000000</us-gaap:LiabilitiesFairValueDisclosure>
    <us-gaap:LiabilitiesFairValueDisclosure
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RhYmxlOjE4ZDdlMmIyYzFhZTRlOTRiOTVlNzY4YTA2NTM3MmJkL3RhYmxlcmFuZ2U6MThkN2UyYjJjMWFlNGU5NGI5NWU3NjhhMDY1MzcyYmRfMzEtOC0xLTEtMA_e54eee54-421a-4574-a88a-5ad398fa3985"
      unitRef="usd">603000000</us-gaap:LiabilitiesFairValueDisclosure>
    <us-gaap:MaximumLengthOfTimeForeignCurrencyCashFlowHedge
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RleHRyZWdpb246MDBlOGE3MGFkYTlmNDA5Yzk4NTQ5YWNkM2NlMjA2NjBfMTkwNQ_6996dee3-8a8d-45f1-b012-21c3b7d4e126">P3Y</us-gaap:MaximumLengthOfTimeForeignCurrencyCashFlowHedge>
    <us-gaap:NotesPayableFairValueDisclosure
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RleHRyZWdpb246MDBlOGE3MGFkYTlmNDA5Yzk4NTQ5YWNkM2NlMjA2NjBfNDI4NA_8a55d0b1-7f03-49f7-9a93-5c2c67c9f1f9"
      unitRef="usd">42200000000</us-gaap:NotesPayableFairValueDisclosure>
    <us-gaap:NotesPayableFairValueDisclosure
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RleHRyZWdpb246MDBlOGE3MGFkYTlmNDA5Yzk4NTQ5YWNkM2NlMjA2NjBfNDI5MQ_98b1e458-14d3-4907-a5f8-ad590ae2bee3"
      unitRef="usd">39400000000</us-gaap:NotesPayableFairValueDisclosure>
    <us-gaap:LongTermDebt
      contextRef="if5d69d61a77e45e8a5690b1247306be3_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RleHRyZWdpb246MDBlOGE3MGFkYTlmNDA5Yzk4NTQ5YWNkM2NlMjA2NjBfNDMzOA_3cdc1212-7b54-4c94-839c-0a0e0f94e940"
      unitRef="usd">37600000000</us-gaap:LongTermDebt>
    <us-gaap:LongTermDebt
      contextRef="i3fa2d8396a304f96bf7624f5d6125c76_I20201231"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82NC9mcmFnOjAwZThhNzBhZGE5ZjQwOWM5ODU0OWFjZDNjZTIwNjYwL3RleHRyZWdpb246MDBlOGE3MGFkYTlmNDA5Yzk4NTQ5YWNkM2NlMjA2NjBfNDM0NQ_40efb6d8-8f5d-464a-a4b3-dde3810cf210"
      unitRef="usd">33000000000</us-gaap:LongTermDebt>
    <us-gaap:DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfOTYxNQ_386c430b-4b8e-46c6-8f7f-dee62b496f29">Derivative instruments&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The Company is exposed to foreign currency exchange rate and interest rate risks related to its business operations. To reduce our risks related to such exposures, we use or have used certain derivative instruments, including foreign currency forward, cross-currency swap, forward interest rate and interest rate swap contracts. We do not use derivatives for speculative- trading purposes.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Cash flow hedges&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;We are exposed to possible changes in the values of certain anticipated foreign currency cash flows resulting from changes in foreign currency exchange rates primarily associated with our euro-denominated international product sales. Increases and decreases in the cash flows associated with our international product sales due to movements in foreign currency exchange rates are partially offset by corresponding increases and decreases in the cash flows from our international operating expenses resulting from these foreign currency exchange rate movements. To further reduce our exposure to foreign currency exchange rate fluctuations with regard to our international product sales, we enter into foreign currency forward contracts to hedge a portion of our projected international product sales up to a maximum of three years into the future; and at any given point in time, a higher percentage of nearer-term projected product sales are being hedged than in successive periods.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;As of September 30, 2021 and December 31, 2020, we had outstanding foreign currency forward contracts with aggregate notional amounts of $5.7 billion and $5.1 billion, respectively. We have designated these foreign currency forward contracts, which are primarily euro based, as cash flow hedges. Accordingly, we report the unrealized gains and losses on these contracts in AOCI in the Condensed Consolidated Balance Sheets, and we reclassify them to Product sales in the Condensed Consolidated Statements of Income in the same periods during which the hedged transactions affect earnings.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;To hedge our exposure to foreign currency exchange rate risk associated with certain of our long-term debt denominated in foreign currencies, we enter into cross-currency swap contracts. Under the terms of such contracts, we paid euros, pounds sterling and Swiss francs and received U.S. dollars for the notional amounts at the inception of the contracts; and based on these notional amounts, we exchange interest payments at fixed rates over the lives of the contracts by paying U.S. dollars and receiving euros, pounds sterling and Swiss francs. In addition, we will pay U.S. dollars to and receive euros, pounds sterling and Swiss francs from the counterparties at the maturities of the contracts for these same notional amounts. The terms of these contracts correspond to the related hedged debt, thereby effectively converting the interest payments and principal repayment on the debt from euros, pounds sterling and Swiss francs to U.S. dollars. We have designated these cross-currency swap contracts as cash flow hedges. Accordingly, the unrealized gains and losses on these contracts are reported in AOCI in the Condensed Consolidated Balance Sheets and reclassified to Other income, net, in the Condensed Consolidated Statements of Income in the same periods during which the hedged debt affects earnings.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The notional amounts and interest rates of our cross-currency swaps as of September 30, 2021, were as follows (notional amounts in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:29.894%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.426%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Foreign currency&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;U.S. dollars&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Hedged notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Notional amounts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Interest rates&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Notional amounts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Interest rates&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1.25% 2022 euro Notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x20ac;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1.3&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,388&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.2&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;0.41% 2023 Swiss franc Bonds&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;CHF&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;700&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;0.4&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;704&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.4&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.00% 2026 euro Notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x20ac;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;750&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.0&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;833&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.9&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5.50% 2026 pound sterling Notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#xa3;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;475&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5.5&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;747&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6.0&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.00% 2029 pound sterling Notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#xa3;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;700&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.0&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,111&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.5&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#231f20;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;In connection with the anticipated issuance of long-term fixed-rate debt, we occasionally enter into forward interest rate contracts in order to hedge the variability in cash flows due to changes in the applicable U.S. Treasury rate between the time we enter into these contracts and the time the related debt is issued. Gains and losses on forward interest rate contracts, which are designated as cash flow hedges, are recognized in AOCI i&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;n the Condensed Consolidated Balance Sheets &lt;/span&gt;&lt;span style="color:#231f20;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;and are amortized into Interest expense, net, in the Condensed Consolidated Statements of Income over the lives of the associated debt issuances. Amounts recognized in connection with forward interest rate swaps during the nine months ended September 30, 2021, and amounts expected to be recognized during the subsequent 12 months are not material.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The unrealized gains and losses recognized in AOCI for our derivative instruments designated as cash flow hedges were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:center"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:45.245%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.619%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.619%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.473%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.624%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Three months ended&lt;br/&gt;September 30,&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Nine months ended&lt;br/&gt;September 30,&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Derivatives in cash flow hedging relationships&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;136&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(163)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;273&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(25)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(120)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;223&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(180)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(107)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 14.5pt;text-align:left;text-indent:-4.5pt;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total unrealized gains (losses)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;16&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;60&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;93&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(132)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Fair value hedges&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;To achieve a desired mix of fixed-rate and floating-rate debt, we entered into interest rate swap contracts that qualified for and were designated as fair value hedges. These interest rate swap contracts effectively convert fixed-rate coupons to floating-rate LIBOR-based coupons over the terms of the related hedge contracts. As of September 30, 2021 and December 31, 2020, we had interest rate swap contracts with aggregate notional amounts of $7.4&#160;billion and $5.9 billion, respectively, that hedge certain portions of our long-term debt issuances. During the three months ended June 30, 2021, we entered into $1.5&#160;billion of interest rate swap contracts to hedge portions of our 2.45% 2030 Notes and 2.30% 2031 Notes (see Note 10, Financing arrangements).&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;For interest rate swap contracts that qualify for and are designated as fair value hedges, we recognize in Interest expense, net, in the Condensed Consolidated Statements of Income the unrealized gain or loss on the derivative resulting from the change in fair value during the period, as well as the offsetting unrealized loss or gain of the hedged item resulting from the change in fair value during the period attributable to the hedged risk. If a hedging relationship involving an interest rate swap contract is terminated, the gain or loss realized on contract termination is recorded as an adjustment to the carrying value of the debt and amortized into Interest expense, net, over the remaining life of the previously hedged debt.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The hedged liabilities and related cumulative-basis adjustments for fair value hedges of those liabilities were recorded in the Condensed Consolidated Balance Sheets as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:37.496%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:13.519%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:13.519%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:13.519%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:13.527%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="text-align:center"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Carrying amounts of hedged liabilities&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:5.2pt;font-weight:700;line-height:100%;position:relative;top:-2.8pt;vertical-align:baseline"&gt;(1)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="text-align:center"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Cumulative amounts of fair value hedging adjustments related to the carrying amounts of the hedged liabilities&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:5.2pt;font-weight:700;line-height:100%;position:relative;top:-2.8pt;vertical-align:baseline"&gt;(2)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated Balance Sheets locations&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Current portion of long-term debt&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;840&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;89&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;90&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;89&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Long-term debt&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,809&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,258&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;281&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;477&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-top:7pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;____________&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;(1)&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt; &#160;&#160;&#160;&#160;Current portion of long-term debt includes $87 million and $89&#160;million of carrying value with discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively. Long-term debt includes $460 million and $525 million of carrying value with discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;(2)&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;&#160;&#160;&#160;&#160;Current portion of long-term debt includes $87 million and $89&#160;million of hedging adjustments on discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively. Long-term debt includes $360 million and $425 million of hedging adjustments on discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Impact of hedging transactions&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The following tables summarize the amounts recorded in income and expense line items and the effects thereon from fair value and cash flow hedging, including discontinued hedging relationships (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:center"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.561%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:40.309%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:7.710%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:7.710%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.151%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:7.710%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.151%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.155%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Three months ended September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Nine months ended September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Product sales&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Interest expense, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Product sales&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Interest expense, net&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total amounts recorded in income and (expense) line items presented in the Condensed Consolidated Statements of Income&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,320&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;73&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(296)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;18,026&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;97&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(862)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;The effects of cash flow and fair value hedging:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Losses on cash flow hedging relationships reclassified out of AOCI:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(5)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(24)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(104)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(190)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Gains (losses) on fair value hedging relationships&#x2014;interest rate swap agreements:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:11.25pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Hedged items&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;(1)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;54&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;195&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Derivatives designated as hedging instruments&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(31)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(128)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div&gt;&lt;span&gt;&lt;br/&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:center"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.561%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:40.309%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:7.710%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.151%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.151%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:7.710%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:7.710%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.155%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Three months ended September 30, 2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Nine months ended September 30, 2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Product sales&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Interest expense, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Product sales&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Interest expense, net&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total amounts recorded in income and (expense) line items presented in the Condensed Consolidated Statements of Income&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,104&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;55&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(302)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;17,906&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;69&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(944)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;The effects of cash flow and fair value hedging:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Gains on cash flow hedging relationships reclassified out of AOCI:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;41&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;158&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;183&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;101&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Gains (losses) on fair value hedging relationships&#x2014;interest rate swap agreements:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:11.25pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Hedged items&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;(1)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;35&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;215&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Derivatives designated as hedging instruments&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(13)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(150)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;__________&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;(1)&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;&#160;&#160;&#160;&#160;Gains on hedged items do not exactly offset losses on the related designated hedging instruments due to amortization of the cumulative amounts of fair value hedging adjustments included in the carrying amount of the hedged debt for discontinued hedging relationships and the recognition of gains on terminated hedges when the corresponding hedged item was paid down in the period.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;No portions of our cash flow hedge contracts were excluded from the assessment of hedge effectiveness. As of September 30, 2021, the net gains expected to be reclassified on our foreign currency and cross-currency swap contracts out of AOCI and into earnings during the next 12 months are not material.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Derivatives not designated as hedges&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;To reduce our exposure to foreign currency fluctuations in certain assets and liabilities denominated in foreign currencies, we enter into foreign currency forward contracts that are not designated as hedging transactions. Most of these exposures are hedged on a month-to-month basis. As of September 30, 2021 and December 31, 2020, the total notional amounts of these foreign currency forward contracts were $0.7 billion and $1.0 billion, respectively. Gains and losses recognized in earnings for our derivative instruments not designated as hedging instruments were not material for the three and nine months ended September 30, 2021 and 2020. &lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The fair values of derivatives included in the Condensed Consolidated Balance Sheets were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:37.496%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:18.344%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.695%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:18.344%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.701%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Derivative assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Derivative liabilities&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated&lt;br/&gt;Balance Sheets locations&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair&#160;values&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated&lt;br/&gt;Balance Sheets locations&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair&#160;values&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Derivatives designated as hedging&#160;instruments:&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other current assets/ Other noncurrent assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;127&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Accrued liabilities/ Other&#160;noncurrent liabilities&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;54&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other current assets/ Other noncurrent assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;119&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Accrued liabilities/ Other&#160;noncurrent liabilities&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;360&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Interest rate swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other current assets/ Other noncurrent assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;29&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Accrued liabilities/ Other&#160;noncurrent liabilities&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;105&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;div style="padding-left:15.75pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total derivatives designated as hedging instruments&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;275&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;519&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div&gt;&lt;span&gt;&lt;br/&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:37.496%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:18.344%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.695%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:18.344%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.701%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Derivative assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Derivative liabilities&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated&lt;br/&gt;Balance Sheets locations&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair&#160;values&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated&lt;br/&gt;Balance Sheets locations&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair&#160;values&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Derivatives designated as hedging instruments:&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other current assets/ Other noncurrent assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;28&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Accrued liabilities/ Other noncurrent liabilities&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;237&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other current assets/ Other noncurrent assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;255&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Accrued liabilities/ Other noncurrent liabilities&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;318&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Interest rate swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other current assets/ Other noncurrent assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;66&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Accrued liabilities/ Other noncurrent liabilities&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;15&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;div style="padding-left:15.75pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total derivatives designated as hedging instruments&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;349&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;570&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Our derivative contracts that were in liability positions as of September 30, 2021, contain certain credit-risk-related contingent provisions that would be triggered if (i)&#160;we were to undergo a change in control and (ii)&#160;our or the surviving entity&#x2019;s creditworthiness deteriorates, which is generally defined as having either a credit rating that is below investment grade or a materially weaker creditworthiness after the change in control. If these events were to occur, the counterparties would have the right, but not the obligation, to close the contracts under early-termination provisions. In such circumstances, the counterparties could request immediate settlement of these contracts for amounts that approximate the then current fair values of the contracts. In addition, our derivative contracts are not subject to any type of master netting arrangement, and amounts due either to or from a counterparty under the contracts may be offset against other amounts due either to or from the same counterparty only if an event of default or termination, as defined, were to occur.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The cash flow effects of our derivative contracts in the Condensed Consolidated Statements of Cash Flows are included in Net cash provided by operating activities, except for the settlement of notional amounts of cross-currency swaps, which are included in Net cash used in financing activities.&lt;/span&gt;&lt;/div&gt;</us-gaap:DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock>
    <us-gaap:DerivativeNotionalAmount
      contextRef="i0d2698f3fe114fea898dbd1bedfa2f5c_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfMTUwOQ_29697b04-8fc1-4196-bb92-daa82d45a51e"
      unitRef="usd">5700000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DerivativeNotionalAmount
      contextRef="i393a4aa6df064753bb52276e7ee04a5d_I20201231"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfMTUxNg_082e671f-4cb9-4556-98f7-13efc628f789"
      unitRef="usd">5100000000</us-gaap:DerivativeNotionalAmount>
    <amgn:ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfOTU1NQ_fa267390-b298-4398-bc6b-442b85468104">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The notional amounts and interest rates of our cross-currency swaps as of September 30, 2021, were as follows (notional amounts in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:29.894%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.420%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:15.426%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Foreign currency&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;U.S. dollars&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Hedged notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Notional amounts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Interest rates&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Notional amounts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Interest rates&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1.25% 2022 euro Notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x20ac;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,250&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1.3&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,388&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.2&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;0.41% 2023 Swiss franc Bonds&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;CHF&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;700&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;0.4&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;704&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.4&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.00% 2026 euro Notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x20ac;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;750&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;2.0&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;833&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;3.9&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5.50% 2026 pound sterling Notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#xa3;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;475&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;5.5&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;747&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6.0&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.00% 2029 pound sterling Notes&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#xa3;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;700&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.0&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;1,111&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;4.5&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;%&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</amgn:ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock>
    <us-gaap:DerivativeNotionalAmount
      contextRef="i7734e6b3c1704f4d8a988d1a61348a77_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfMy0yLTEtMS0w_46af1c7a-9a82-4c04-b96f-08ff7e386219"
      unitRef="eur">1250000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DerivativeFixedInterestRate
      contextRef="i399b619e02804ea2ba1db1e14f9ab716_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfMy00LTEtMS0w_f5d3a09a-60ea-4d28-8c74-c5948c724259"
      unitRef="number">0.013</us-gaap:DerivativeFixedInterestRate>
    <us-gaap:DerivativeNotionalAmount
      contextRef="i7734e6b3c1704f4d8a988d1a61348a77_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfMy02LTEtMS0w_1afbff94-6d23-4366-9aac-f2a1e0758410"
      unitRef="usd">1388000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DerivativeFixedInterestRate
      contextRef="ib1e612626d9f43b0b769e555166d81e3_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfMy04LTEtMS0w_fe47d4fb-669f-4e79-afc2-d546b125d81b"
      unitRef="number">0.032</us-gaap:DerivativeFixedInterestRate>
    <us-gaap:DerivativeNotionalAmount
      contextRef="ifc7f48af9c2b4b2681e9bd3d3af61b12_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNC0yLTEtMS0w_c1771bf7-be58-4c0f-bcf4-cb460a52680d"
      unitRef="chf">700000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DerivativeFixedInterestRate
      contextRef="iba8a92586e2b4417a662a578f1511b3c_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNC00LTEtMS0w_d020cec9-6326-4c46-9f56-7e18a97656cf"
      unitRef="number">0.004</us-gaap:DerivativeFixedInterestRate>
    <us-gaap:DerivativeNotionalAmount
      contextRef="ifc7f48af9c2b4b2681e9bd3d3af61b12_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNC02LTEtMS0w_d2ad863b-e01d-4db0-a1a1-7769cc77f8b5"
      unitRef="usd">704000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DerivativeFixedInterestRate
      contextRef="i850f90a0299d43458bd33796e0371d13_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNC04LTEtMS0w_9abcc88b-8e60-4031-8bba-cd43c4aea62b"
      unitRef="number">0.034</us-gaap:DerivativeFixedInterestRate>
    <us-gaap:DerivativeNotionalAmount
      contextRef="i1ee3b6969d0e47798c3ab0adfa9e44d6_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNS0yLTEtMS0w_a1ae7dab-7f18-44a0-9d28-d7c1c93c2afe"
      unitRef="eur">750000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DerivativeFixedInterestRate
      contextRef="i3334c66245af46b9a585510eebce55e0_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNS00LTEtMS0w_d22db526-4fc1-4254-b0a9-c6c3e2711154"
      unitRef="number">0.020</us-gaap:DerivativeFixedInterestRate>
    <us-gaap:DerivativeNotionalAmount
      contextRef="i1ee3b6969d0e47798c3ab0adfa9e44d6_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNS02LTEtMS0w_d783145e-dd0d-4b7b-8a97-8bdc323bcd0f"
      unitRef="usd">833000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DerivativeFixedInterestRate
      contextRef="if435a46c948846aca4c19571c1f10bc9_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNS04LTEtMS0w_1c6ef3ac-63a8-43ec-ad6e-2ed5723916b0"
      unitRef="number">0.039</us-gaap:DerivativeFixedInterestRate>
    <us-gaap:DerivativeNotionalAmount
      contextRef="if10b3957b204438a86f3b2309e56842a_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNi0yLTEtMS0w_a13c4e1d-7d8c-461e-a3b1-0a992780bb84"
      unitRef="gbp">475000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DerivativeFixedInterestRate
      contextRef="i5e8c12261fc243ddbd412fb565f1b116_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNi00LTEtMS0w_82effbc2-3dc4-4c48-867b-39e7bab7c2d0"
      unitRef="number">0.055</us-gaap:DerivativeFixedInterestRate>
    <us-gaap:DerivativeNotionalAmount
      contextRef="if10b3957b204438a86f3b2309e56842a_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNi02LTEtMS0w_f21efa09-9eab-49a6-a30c-3ac38a5c9f86"
      unitRef="usd">747000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DerivativeFixedInterestRate
      contextRef="i603ad1820fef4e8a8f960404cd15b244_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNi04LTEtMS0w_96608682-d3ee-4fdd-a487-90fa609e396e"
      unitRef="number">0.060</us-gaap:DerivativeFixedInterestRate>
    <us-gaap:DerivativeNotionalAmount
      contextRef="id9403f32bf014bd1a180b462efe73171_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNy0yLTEtMS0w_1b99733f-a41c-4e5f-8da8-f218cb04347a"
      unitRef="gbp">700000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DerivativeFixedInterestRate
      contextRef="iece903822c1c413ba21f23e1a3a8817b_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNy00LTEtMS0w_78bf4de2-47c1-4b21-8429-7d7d122c6952"
      unitRef="number">0.040</us-gaap:DerivativeFixedInterestRate>
    <us-gaap:DerivativeNotionalAmount
      contextRef="id9403f32bf014bd1a180b462efe73171_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNy02LTEtMS0w_7e8f46a4-4205-4563-bf27-c980c850375f"
      unitRef="usd">1111000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DerivativeFixedInterestRate
      contextRef="if9749c18ee4d4475925e12e9fb9d6ec4_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmMxY2QzYTMwYWQzNTRlZmRiOGY2YmU1OTE1N2E5OGRlL3RhYmxlcmFuZ2U6YzFjZDNhMzBhZDM1NGVmZGI4ZjZiZTU5MTU3YTk4ZGVfNy04LTEtMS0w_1f3cbd86-46d8-4fc5-8a5c-09cc3e664c1b"
      unitRef="number">0.045</us-gaap:DerivativeFixedInterestRate>
    <us-gaap:ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfOTU4OA_f3ec2d0f-9acd-4817-a6a2-d67f70df46de">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The unrealized gains and losses recognized in AOCI for our derivative instruments designated as cash flow hedges were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:center"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:45.245%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.619%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.619%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.473%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:11.624%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Three months ended&lt;br/&gt;September 30,&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Nine months ended&lt;br/&gt;September 30,&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Derivatives in cash flow hedging relationships&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;136&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(163)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;273&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(25)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(120)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;223&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(180)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(107)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 14.5pt;text-align:left;text-indent:-4.5pt;vertical-align:top"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total unrealized gains (losses)&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;16&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;60&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;93&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(132)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</us-gaap:ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax
      contextRef="ia82e4d4dd7624199b0b9823339e7521e_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMi0yLTEtMS0w_36f77d38-21b1-494c-bd53-b8ff1a6cb548"
      unitRef="usd">136000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax
      contextRef="idfede3337ef54161bc5bd47fd541f5ef_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMi00LTEtMS0w_13ec2e4c-a928-4ab9-9ecc-70a992fa789d"
      unitRef="usd">-163000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax
      contextRef="icc5c639f364e45baa662901e97a7de40_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMi02LTEtMS0w_bccc045b-03cd-4288-bbeb-c31cb7ee94a5"
      unitRef="usd">273000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax
      contextRef="i01d039e9716e4293aacd1732c82a9104_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMi04LTEtMS0w_93d7d777-bd7a-4398-869f-346c0195a0c9"
      unitRef="usd">-25000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax
      contextRef="i429f2cf41442431d854b0802e1818b63_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMy0yLTEtMS0w_fae9bff0-f15a-4ff7-8d02-e62678abb64d"
      unitRef="usd">-120000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax
      contextRef="if6773803670d44b2ae4b1519c9996aac_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMy00LTEtMS0w_0923f3bb-a640-4a4a-a368-e6de884dff89"
      unitRef="usd">223000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax
      contextRef="i5c44b32339c742969f187797f4ae3956_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMy02LTEtMS0w_a5797152-29af-468f-9cd9-6d7c0a98162a"
      unitRef="usd">-180000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax
      contextRef="icb1c3e075c0447c0a8d96118c3b1ccc0_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfMy04LTEtMS0w_672ca9da-f4e4-4ebb-b18a-796a790d5c66"
      unitRef="usd">-107000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax
      contextRef="i53af41683cb14e598e98d0cdd138caeb_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfNS0yLTEtMS0w_30a4949a-a882-4e59-b2e8-80eb5c9e6c4f"
      unitRef="usd">16000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax
      contextRef="i9a23429c3e7047b1be61aaf1c0cd68ff_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfNS00LTEtMS0w_0a1897ec-3b91-49a3-a685-81e7a2a03297"
      unitRef="usd">60000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax
      contextRef="i4dfa001ded2a48d2a902aa13f44f8684_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfNS02LTEtMS0w_e979382c-70fa-4c5f-bcef-1c7b468ead37"
      unitRef="usd">93000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax>
    <us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax
      contextRef="i3253252da82e4f4cb4e51fe1f6a14b85_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjNjY2VkN2NjM2RkODRmOTM4NzM0NDZkM2QyMjk3ZjMwL3RhYmxlcmFuZ2U6M2NjZWQ3Y2MzZGQ4NGY5Mzg3MzQ0NmQzZDIyOTdmMzBfNS04LTEtMS0w_049b1e3f-5d52-496a-9712-842c2ab7ceb0"
      unitRef="usd">-132000000</us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax>
    <us-gaap:DerivativeNotionalAmount
      contextRef="i5d9649b14f6944e6b32f46773afd94df_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNDc0OQ_b4c4cf55-0b87-408a-ac66-2d8c378429cd"
      unitRef="usd">7400000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DerivativeNotionalAmount
      contextRef="i93734d89c57d45e99c00e58787a09f5e_I20201231"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNDc1Ng_3e581e6b-acf6-4d54-b713-ef00e3d52f6d"
      unitRef="usd">5900000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DerivativeNotionalAmount
      contextRef="ifb6251f8399b4dc69935ab1011467098_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNDg5Ng_5290d673-bfc0-40d1-a026-8c62b0aeea8c"
      unitRef="usd">1500000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="ia3569d0c6bcd4203a1148cb8dda584fe_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNDk1Ng_a4b8ca7f-f36f-413c-ac9b-f3a3eaece057"
      unitRef="number">0.0245</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:DebtInstrumentInterestRateStatedPercentage
      contextRef="i2c54babb8e9f4eb8b43722a88181da66_I20210930"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNDk3NA_64ecda43-17f2-4649-b094-6426591c3723"
      unitRef="number">0.0230</us-gaap:DebtInstrumentInterestRateStatedPercentage>
    <us-gaap:ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfOTU5OQ_03c8ff6e-7f0e-496a-867c-cb95a52a4eac">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The hedged liabilities and related cumulative-basis adjustments for fair value hedges of those liabilities were recorded in the Condensed Consolidated Balance Sheets as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:37.496%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:13.519%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:13.519%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:13.519%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:13.527%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="text-align:center"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Carrying amounts of hedged liabilities&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:5.2pt;font-weight:700;line-height:100%;position:relative;top:-2.8pt;vertical-align:baseline"&gt;(1)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="text-align:center"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Cumulative amounts of fair value hedging adjustments related to the carrying amounts of the hedged liabilities&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:5.2pt;font-weight:700;line-height:100%;position:relative;top:-2.8pt;vertical-align:baseline"&gt;(2)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated Balance Sheets locations&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Current portion of long-term debt&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;840&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;89&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;90&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;89&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Long-term debt&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,809&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,258&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;281&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;477&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="margin-top:7pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;____________&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;(1)&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt; &#160;&#160;&#160;&#160;Current portion of long-term debt includes $87 million and $89&#160;million of carrying value with discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively. Long-term debt includes $460 million and $525 million of carrying value with discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;(2)&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;&#160;&#160;&#160;&#160;Current portion of long-term debt includes $87 million and $89&#160;million of hedging adjustments on discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively. Long-term debt includes $360 million and $425 million of hedging adjustments on discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively.&lt;/span&gt;&lt;/div&gt;</us-gaap:ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock>
    <us-gaap:HedgedLiabilityFairValueHedge
      contextRef="i44869b7e4ad641a5bc2667496e4c4b2c_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMi0yLTEtMS0w_479b2393-f33d-4957-aec4-dd948e50d3ce"
      unitRef="usd">840000000</us-gaap:HedgedLiabilityFairValueHedge>
    <us-gaap:HedgedLiabilityFairValueHedge
      contextRef="ia18546e9b5354e3da7193d7dab9c11f3_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMi00LTEtMS0w_2ec8a0a4-7a2c-4b6e-a3f4-8f9044145a0d"
      unitRef="usd">89000000</us-gaap:HedgedLiabilityFairValueHedge>
    <us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease
      contextRef="i44869b7e4ad641a5bc2667496e4c4b2c_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMi02LTEtMS0w_409d41ea-320c-4eec-9164-1ae6eeb88dce"
      unitRef="usd">90000000</us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease>
    <us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease
      contextRef="ia18546e9b5354e3da7193d7dab9c11f3_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMi04LTEtMS0w_9725522b-2736-47fc-8981-7b36b36987b5"
      unitRef="usd">89000000</us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease>
    <us-gaap:HedgedLiabilityFairValueHedge
      contextRef="i040b7e3625734005983b800042806116_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMy0yLTEtMS0w_4132880b-54a8-4760-84bd-7f74501e4017"
      unitRef="usd">6809000000</us-gaap:HedgedLiabilityFairValueHedge>
    <us-gaap:HedgedLiabilityFairValueHedge
      contextRef="if82a04ddb1484b4d9d685c69534d60ee_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMy00LTEtMS0w_a290e73e-7bdc-475a-9246-022d8ae8c5c5"
      unitRef="usd">6258000000</us-gaap:HedgedLiabilityFairValueHedge>
    <us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease
      contextRef="i040b7e3625734005983b800042806116_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMy02LTEtMS0w_f4ac1012-bc8c-4256-af1f-f1b7481f7894"
      unitRef="usd">281000000</us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease>
    <us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease
      contextRef="if82a04ddb1484b4d9d685c69534d60ee_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjY2NDk2ODZhOTQ2ZDQ0ZGVhNzhmMWI4YTVjZjJlNDE2L3RhYmxlcmFuZ2U6NjY0OTY4NmE5NDZkNDRkZWE3OGYxYjhhNWNmMmU0MTZfMy04LTEtMS0w_8779c9b9-d9c7-4736-8dc5-3edb9f066d0d"
      unitRef="usd">477000000</us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease>
    <amgn:HedgedLiabilityDiscontinuedFairValueHedge
      contextRef="i44869b7e4ad641a5bc2667496e4c4b2c_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNjAyMA_3ab4a755-519f-4181-a9a7-61eefb39fbef"
      unitRef="usd">87000000</amgn:HedgedLiabilityDiscontinuedFairValueHedge>
    <amgn:HedgedLiabilityDiscontinuedFairValueHedge
      contextRef="ia18546e9b5354e3da7193d7dab9c11f3_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNzY5NjU4MTQwNDE1OQ_164682f5-3dab-4f7c-b1bd-5556048bc20a"
      unitRef="usd">89000000</amgn:HedgedLiabilityDiscontinuedFairValueHedge>
    <amgn:HedgedLiabilityDiscontinuedFairValueHedge
      contextRef="i040b7e3625734005983b800042806116_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNjE0Mg_86fe4381-1207-471e-a852-f91e804a0ee9"
      unitRef="usd">460000000</amgn:HedgedLiabilityDiscontinuedFairValueHedge>
    <amgn:HedgedLiabilityDiscontinuedFairValueHedge
      contextRef="if82a04ddb1484b4d9d685c69534d60ee_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNjE0OQ_489dfccb-e115-4a6a-9259-cfd6a77b26af"
      unitRef="usd">525000000</amgn:HedgedLiabilityDiscontinuedFairValueHedge>
    <us-gaap:HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease
      contextRef="i44869b7e4ad641a5bc2667496e4c4b2c_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNjI4OA_1588cf9c-9cd1-409a-9b22-873a76983b24"
      unitRef="usd">87000000</us-gaap:HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease>
    <us-gaap:HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease
      contextRef="ia18546e9b5354e3da7193d7dab9c11f3_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNzY5NjU4MTQwNDE0Ng_b0bcbd7c-7793-44bc-838c-fde7ef26e3c9"
      unitRef="usd">89000000</us-gaap:HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease>
    <us-gaap:HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease
      contextRef="i040b7e3625734005983b800042806116_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNjQxMw_8f500ae4-525e-4b44-8740-02483ddcb49a"
      unitRef="usd">360000000</us-gaap:HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease>
    <us-gaap:HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease
      contextRef="if82a04ddb1484b4d9d685c69534d60ee_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNjQyMA_ef2ee5ad-7955-4a73-9429-2a297bb0ec37"
      unitRef="usd">425000000</us-gaap:HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease>
    <us-gaap:ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfOTU5MA_d736f285-def6-41fe-8362-e8b3a1a1f96c">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The following tables summarize the amounts recorded in income and expense line items and the effects thereon from fair value and cash flow hedging, including discontinued hedging relationships (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:center"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.561%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:40.309%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:7.710%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:7.710%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.151%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:7.710%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.151%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.155%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Three months ended September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Nine months ended September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Product sales&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Interest expense, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Product sales&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Interest expense, net&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total amounts recorded in income and (expense) line items presented in the Condensed Consolidated Statements of Income&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,320&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;73&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(296)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;18,026&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;97&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(862)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;The effects of cash flow and fair value hedging:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Losses on cash flow hedging relationships reclassified out of AOCI:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(5)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(24)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(104)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(190)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Gains (losses) on fair value hedging relationships&#x2014;interest rate swap agreements:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:11.25pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Hedged items&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;(1)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;54&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;195&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Derivatives designated as hedging instruments&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(31)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(128)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div&gt;&lt;span&gt;&lt;br/&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:center"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.561%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:40.309%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:7.710%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.151%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.151%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:7.710%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:7.710%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.534%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.155%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Three months ended September 30, 2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Nine months ended September 30, 2020&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Product sales&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Interest expense, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Product sales&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Other income, net&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Interest expense, net&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total amounts recorded in income and (expense) line items presented in the Condensed Consolidated Statements of Income&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;6,104&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;55&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(302)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;17,906&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;69&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(944)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;The effects of cash flow and fair value hedging:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Gains on cash flow hedging relationships reclassified out of AOCI:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;41&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;158&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;183&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;101&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Gains (losses) on fair value hedging relationships&#x2014;interest rate swap agreements:&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:11.25pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Hedged items&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;(1)&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;35&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;215&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Derivatives designated as hedging instruments&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(13)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;&#x2014;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;(150)&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div style="padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;__________&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;(1)&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;&#160;&#160;&#160;&#160;Gains on hedged items do not exactly offset losses on the related designated hedging instruments due to amortization of the cumulative amounts of fair value hedging adjustments included in the carrying amount of the hedged debt for discontinued hedging relationships and the recognition of gains on terminated hedges when the corresponding hedged item was paid down in the period.&lt;/span&gt;&lt;/div&gt;</us-gaap:ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i237db287808149dc88791dd0402e8c8d_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMy0yLTEtMS0w_ff29ea1e-ea60-4f6a-8628-3606bbd07914"
      unitRef="usd">6320000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMy00LTEtMS0w_50f25787-f8b7-4286-9223-104aac7a2f6a"
      unitRef="usd">73000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:InterestExpenseDebt
      contextRef="i5c9f553a648c448983067995570fff40_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMy02LTEtMS0w_60beef6d-075a-4780-b2c3-135950e20e71"
      unitRef="usd">296000000</us-gaap:InterestExpenseDebt>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i3eb445431b634cc6b3e61727cef7b877_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMy04LTEtMS0w_16c8f25e-7b9e-4696-8116-e3fe10888409"
      unitRef="usd">18026000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMy0xMC0xLTEtMA_a6b453ed-7e85-4974-b7c2-ea074d62dfe9"
      unitRef="usd">97000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:InterestExpenseDebt
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMy0xMi0xLTEtMA_33730618-6b0c-40e4-bf6b-43e3fdd300e2"
      unitRef="usd">862000000</us-gaap:InterestExpenseDebt>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i189a6a6830c84033985ac2eb0166844f_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfNi0yLTEtMS0w_e96719db-e1c7-4879-9f10-71bf00edc9d8"
      unitRef="usd">-5000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i84ce59b928bc4625b81e9ba243566b0b_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfNi04LTEtMS0w_660f36ba-353e-4b34-ba66-15596b9dfede"
      unitRef="usd">-24000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i44310cb41e2e4aaabf0dc581c8c2c4ea_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfNy00LTEtMS0w_ff0c280c-0988-4944-90ff-c1337c9e702e"
      unitRef="usd">-104000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i2b29edf642674757a33b45fcec1cc8b4_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfNy0xMC0xLTEtMA_cb39aac0-e0bb-4fb0-9a28-ec8576d37dc6"
      unitRef="usd">-190000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1
      contextRef="icc69b7bd76f6439ea5993cfe7cab843b_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMTAtNi0xLTEtMA_4b76b8a7-1f92-4288-bb91-16b7e4ba617c"
      unitRef="usd">54000000</us-gaap:ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1>
    <us-gaap:ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1
      contextRef="i2368706943c748edb9e18c4bf06ef9ad_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMTAtMTItMS0xLTA_e0f13045-16d7-4d87-954b-35353551a39e"
      unitRef="usd">195000000</us-gaap:ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1>
    <us-gaap:ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1
      contextRef="icc69b7bd76f6439ea5993cfe7cab843b_D20210701-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMTEtNi0xLTEtMA_01033cff-e7e3-4e02-aff4-bf2e0b886754"
      unitRef="usd">-31000000</us-gaap:ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1>
    <us-gaap:ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1
      contextRef="i2368706943c748edb9e18c4bf06ef9ad_D20210101-20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ1ZGYwYTdmOTBjYTQzOTU5N2IxNmY1ZDNhODYwYjc2L3RhYmxlcmFuZ2U6ZDVkZjBhN2Y5MGNhNDM5NTk3YjE2ZjVkM2E4NjBiNzZfMTEtMTItMS0xLTA_a88353fb-ed7f-4d91-8c7a-e0091f33d181"
      unitRef="usd">-128000000</us-gaap:ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="icc3aae43096e4ee2941dfecfdc9776ad_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMy0yLTEtMS0w_5c20c93e-45a0-43e1-aad8-369b7e18c3c6"
      unitRef="usd">6104000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMy00LTEtMS0w_fc7c6426-e226-4770-a569-b617c3f6a612"
      unitRef="usd">55000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:InterestExpenseDebt
      contextRef="i74edd277075b4be0b03a288e4d476372_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMy02LTEtMS0w_366316c7-ff2b-40a9-a2dc-80781b7d695a"
      unitRef="usd">302000000</us-gaap:InterestExpenseDebt>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i556e038dae96477cbe84bc1653ed5883_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMy04LTEtMS0w_533cab51-3c88-4291-849e-212c66973fdb"
      unitRef="usd">17906000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMy0xMC0xLTEtMA_aaa5c8a8-3684-4790-8977-73e23e7a0b08"
      unitRef="usd">69000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:InterestExpenseDebt
      contextRef="i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMy0xMi0xLTEtMA_a63d2d76-b257-41a6-ae59-bbefefcfe7fc"
      unitRef="usd">944000000</us-gaap:InterestExpenseDebt>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="ieccef0ffb45a4fdcbd44c752c16e6068_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfNi0yLTEtMS0w_4394ae65-2f39-4a83-838e-55ef6401a965"
      unitRef="usd">41000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
      contextRef="i503ef52a14c747cb9fab04a1e85b81d1_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfNi04LTEtMS0w_2dcf81c5-9dfc-4c1a-9396-a59bae34cd79"
      unitRef="usd">158000000</us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="iaef608c4412a4e94ba0fb53cc211b333_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfNy00LTEtMS0w_63291c89-6652-4542-80a0-fd5fe8cc5b50"
      unitRef="usd">183000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:NonoperatingIncomeExpense
      contextRef="i1da13ce0b09e46ae9200663802380083_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfNy0xMC0xLTEtMA_f1a877c4-f710-4557-abd7-945cbcc22233"
      unitRef="usd">101000000</us-gaap:NonoperatingIncomeExpense>
    <us-gaap:ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1
      contextRef="i7c59c26b885d420cbebeaff7c5823719_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMTAtNi0xLTEtMA_aa390963-4ab4-4a4a-90b8-1f19d464c5d1"
      unitRef="usd">35000000</us-gaap:ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1>
    <us-gaap:ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1
      contextRef="ife3621a3597c4b819c57657a0cacdc1d_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMTAtMTItMS0xLTA_ba14934d-6abf-48ea-8259-3ed0ff735fa2"
      unitRef="usd">215000000</us-gaap:ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1>
    <us-gaap:ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1
      contextRef="i7c59c26b885d420cbebeaff7c5823719_D20200701-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMTEtNi0xLTEtMA_a72ec516-54fd-4848-b89f-d6e0991fee57"
      unitRef="usd">-13000000</us-gaap:ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1>
    <us-gaap:ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1
      contextRef="ife3621a3597c4b819c57657a0cacdc1d_D20200101-20200930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjkzZDY3ZjM2MmE2OTRhN2E5OWY3MGQzNjQ0MzMzZWQ2L3RhYmxlcmFuZ2U6OTNkNjdmMzYyYTY5NGE3YTk5ZjcwZDM2NDQzMzNlZDZfMTEtMTItMS0xLTA_054ec489-8b54-4107-bfa9-dcf3b8beb9ec"
      unitRef="usd">-150000000</us-gaap:ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1>
    <us-gaap:DerivativeNotionalAmount
      contextRef="i6967f808be0e42dd8d431bf91fbf8fda_I20210930"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNzg1OA_43c96355-8251-46e5-8a7b-4efdc2007d89"
      unitRef="usd">700000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:DerivativeNotionalAmount
      contextRef="icf8902c539da490aa8f154995bfad656_I20201231"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfNzg2NQ_c5382435-a734-402d-bd87-874479fa37b8"
      unitRef="usd">1000000000</us-gaap:DerivativeNotionalAmount>
    <us-gaap:ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RleHRyZWdpb246ZjAwOTgyMGYwY2E1NDlmYzk1MDRiMzY4YzJmZDQ4MDlfOTU4MA_a3ae4b51-39e6-40f2-bcb0-eca1eb4c5024">&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The fair values of derivatives included in the Condensed Consolidated Balance Sheets were as follows (in millions):&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:37.496%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:18.344%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.695%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:18.344%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.701%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Derivative assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Derivative liabilities&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;September 30, 2021&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated&lt;br/&gt;Balance Sheets locations&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair&#160;values&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated&lt;br/&gt;Balance Sheets locations&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair&#160;values&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Derivatives designated as hedging&#160;instruments:&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other current assets/ Other noncurrent assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;127&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Accrued liabilities/ Other&#160;noncurrent liabilities&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;54&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other current assets/ Other noncurrent assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;119&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Accrued liabilities/ Other&#160;noncurrent liabilities&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;360&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Interest rate swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other current assets/ Other noncurrent assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;29&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Accrued liabilities/ Other&#160;noncurrent liabilities&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;105&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;div style="padding-left:15.75pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total derivatives designated as hedging instruments&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;275&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;519&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;&lt;div&gt;&lt;span&gt;&lt;br/&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt"&gt;&lt;table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"&gt;&lt;tr&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:37.496%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:18.344%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.695%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:18.344%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:0.530%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;td style="width:1.0%"/&gt;&lt;td style="width:8.701%"/&gt;&lt;td style="width:0.1%"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%"&gt;&#160;&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Derivative assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Derivative liabilities&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;December 31, 2020&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated&lt;br/&gt;Balance Sheets locations&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair&#160;values&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Condensed Consolidated&lt;br/&gt;Balance Sheets locations&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Fair&#160;values&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%"&gt;Derivatives designated as hedging instruments:&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Foreign currency contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other current assets/ Other noncurrent assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;28&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Accrued liabilities/ Other noncurrent liabilities&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;237&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Cross-currency swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other current assets/ Other noncurrent assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;255&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Accrued liabilities/ Other noncurrent liabilities&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;318&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Interest rate swap contracts&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Other current assets/ Other noncurrent assets&lt;/span&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;66&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;div style="padding-left:9pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Accrued liabilities/ Other noncurrent liabilities&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#ffffff;padding:0 1pt"/&gt;&lt;td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;15&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"&gt;&lt;div style="padding-left:15.75pt;text-indent:-9pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;Total derivatives designated as hedging instruments&lt;/span&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;349&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td colspan="3" style="background-color:#cceeff;padding:0 1pt"/&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;$&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"&gt;570&#160;&lt;/span&gt;&lt;/td&gt;&lt;td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;td colspan="3" style="display:none"/&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/div&gt;</us-gaap:ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock>
    <us-gaap:DerivativeFairValueOfDerivativeAsset
      contextRef="i3847de63b915449dacb3fe5ac480d2d4_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfMy00LTEtMS0w_c06744db-81d8-4214-ac2f-2fe38d86f6f0"
      unitRef="usd">127000000</us-gaap:DerivativeFairValueOfDerivativeAsset>
    <us-gaap:DerivativeFairValueOfDerivativeLiability
      contextRef="i6dd8345dd5db4bef839be567148829c8_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfMy04LTEtMS0w_f3c622d9-39b2-4fd4-8117-c60d8bed81b2"
      unitRef="usd">54000000</us-gaap:DerivativeFairValueOfDerivativeLiability>
    <us-gaap:DerivativeFairValueOfDerivativeAsset
      contextRef="i66933df39b94465f8542b2c374051858_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfNC00LTEtMS0w_bd0b92e8-4338-4501-be35-2128002cdc3f"
      unitRef="usd">119000000</us-gaap:DerivativeFairValueOfDerivativeAsset>
    <us-gaap:DerivativeFairValueOfDerivativeLiability
      contextRef="iae17d6c368384d6081046e9199b88942_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfNC04LTEtMS0w_44c2499c-c218-4e1e-be3d-f1b17a82a0ed"
      unitRef="usd">360000000</us-gaap:DerivativeFairValueOfDerivativeLiability>
    <us-gaap:DerivativeFairValueOfDerivativeAsset
      contextRef="i6dc0acd554d1417d8ee9828564a05a4d_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfNS00LTEtMS0w_db5f28ac-6700-458e-a74a-5801d13b6009"
      unitRef="usd">29000000</us-gaap:DerivativeFairValueOfDerivativeAsset>
    <us-gaap:DerivativeFairValueOfDerivativeLiability
      contextRef="id9f3f0d26a574ed0a5c0ee09137be2a1_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfNS04LTEtMS0w_bc85ddd4-f330-42aa-8946-8422a77994a5"
      unitRef="usd">105000000</us-gaap:DerivativeFairValueOfDerivativeLiability>
    <us-gaap:DerivativeFairValueOfDerivativeAsset
      contextRef="ic5f888563c394d598153a924bfacbca4_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfNy00LTEtMS0w_820827ad-ab03-455e-b302-e7afcf397f3b"
      unitRef="usd">275000000</us-gaap:DerivativeFairValueOfDerivativeAsset>
    <us-gaap:DerivativeFairValueOfDerivativeLiability
      contextRef="ic5f888563c394d598153a924bfacbca4_I20210930"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOjlkZTE2OTc0ZGE2NjRkNWVhZDBkMzhlYWE1ZDVhOTI4L3RhYmxlcmFuZ2U6OWRlMTY5NzRkYTY2NGQ1ZWFkMGQzOGVhYTVkNWE5MjhfNy04LTEtMS0w_9e2c8815-094e-463f-ba12-41d6aff42dd9"
      unitRef="usd">519000000</us-gaap:DerivativeFairValueOfDerivativeLiability>
    <us-gaap:DerivativeFairValueOfDerivativeAsset
      contextRef="i78df11bae6c9411f901b63b66ef4b7d7_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfMy00LTEtMS0w_3d258ed3-4550-401b-9364-5d3102b0f96d"
      unitRef="usd">28000000</us-gaap:DerivativeFairValueOfDerivativeAsset>
    <us-gaap:DerivativeFairValueOfDerivativeLiability
      contextRef="i03f545cb57bd498bb5e65da04d641b83_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfMy04LTEtMS0w_69d13c4f-27a6-4e54-8039-ad10faac0652"
      unitRef="usd">237000000</us-gaap:DerivativeFairValueOfDerivativeLiability>
    <us-gaap:DerivativeFairValueOfDerivativeAsset
      contextRef="ie0dc252346c94bbc92e44b537f39ccd3_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfNC00LTEtMS0w_ca93795f-5957-4532-bfb5-c5b65ebf9d9a"
      unitRef="usd">255000000</us-gaap:DerivativeFairValueOfDerivativeAsset>
    <us-gaap:DerivativeFairValueOfDerivativeLiability
      contextRef="i91c7206f80d44590a0419f271b3f7a9e_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfNC04LTEtMS0w_4c0f76c1-0d25-498f-bc87-38c2f5db21ee"
      unitRef="usd">318000000</us-gaap:DerivativeFairValueOfDerivativeLiability>
    <us-gaap:DerivativeFairValueOfDerivativeAsset
      contextRef="i44a11e7c427b47569c640463a3089cf8_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfNi00LTEtMS0w_4fd77662-9157-4276-b2d3-b8c7f2d0cf43"
      unitRef="usd">66000000</us-gaap:DerivativeFairValueOfDerivativeAsset>
    <us-gaap:DerivativeFairValueOfDerivativeLiability
      contextRef="ide90c3477b63435f97b32f9aba190c02_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfNi04LTEtMS0w_059b83af-ada9-4937-b6da-f99ef6697b4f"
      unitRef="usd">15000000</us-gaap:DerivativeFairValueOfDerivativeLiability>
    <us-gaap:DerivativeFairValueOfDerivativeAsset
      contextRef="i76a5a06206924308b632f5ca3c34bd97_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfNy00LTEtMS0w_79b72382-d867-40b0-ade4-f983a0fb59d5"
      unitRef="usd">349000000</us-gaap:DerivativeFairValueOfDerivativeAsset>
    <us-gaap:DerivativeFairValueOfDerivativeLiability
      contextRef="i76a5a06206924308b632f5ca3c34bd97_I20201231"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV82Ny9mcmFnOmYwMDk4MjBmMGNhNTQ5ZmM5NTA0YjM2OGMyZmQ0ODA5L3RhYmxlOmQ4ZDQ3YTZlNGEyNDQzNDFhMDRjMGNkNGIzNjgwZTMzL3RhYmxlcmFuZ2U6ZDhkNDdhNmU0YTI0NDM0MWEwNGMwY2Q0YjM2ODBlMzNfNy04LTEtMS0w_5b45e0bc-6878-4b2f-91c4-ffbc6d14bc4f"
      unitRef="usd">570000000</us-gaap:DerivativeFairValueOfDerivativeLiability>
    <us-gaap:CommitmentsAndContingenciesDisclosureTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83MC9mcmFnOjZmMzVmMjIzNjJhNzQwNjliZWM5MjRhMGNmOTY0NjdmL3RleHRyZWdpb246NmYzNWYyMjM2MmE3NDA2OWJlYzkyNGEwY2Y5NjQ2N2ZfOTA0OA_cdb77063-7d7e-4a32-96c8-00ca7004949e">Contingencies and commitments&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Contingencies&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;In the ordinary course of business, we are involved in various legal proceedings, government investigations and other matters that are complex in nature and have outcomes that are difficult to predict. See our Annual Report on Form 10-K for the year ended December 31, 2020, Part I, Item 1A. Risk Factors&#x2014;&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Our business may be affected by litigation and government investigations. &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;We describe our legal proceedings and other matters that are significant or that we believe could become significant in this footnote; in Note 19, Contingencies and commitments, to the consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2020; in Note 12, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended March 31, 2021; and in Note 13, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended June 30, 2021.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;We record accruals for loss contingencies to the extent that we conclude it is probable that a liability has been incurred and the amount of the related loss can be reasonably estimated. We evaluate, on a quarterly basis, developments in legal proceedings and other matters that could cause an increase or decrease in the amount of the liability that has been accrued previously.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Our legal proceedings involve various aspects of our business and a variety of claims, some of which present novel factual allegations and/or unique legal theories. In each of the matters described in this filing; in Note 19, Contingencies and commitments, to the consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2020; in Note 12, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended March 31, 2021; or in Note 13, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended June 30, 2021, in which we could incur a liability, our opponents seek an award of a not-yet-quantified amount of damages or an amount that is not material. In addition, a number of the matters pending against us are at very early stages of the legal process, which in complex proceedings of the sort we face often extend for several years. As a result, none of the matters described in this filing; in Note 19, Contingencies and commitments, to the consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2020; in Note 12, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended March 31, 2021; or in Note 13, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended June 30, 2021, in which we could incur a liability, have progressed sufficiently through discovery and/or the development of important factual information and legal issues to enable us to estimate a range of possible loss, if any, or such amounts are not material. While it is not possible to accurately predict or determine the eventual outcomes of these matters, an adverse determination in one or more of these matters currently pending could have a material adverse effect on our consolidated results of operations, financial position or cash flows.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Certain recent developments concerning our legal proceedings and other matters are discussed below:&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Abbreviated New Drug Application (ANDA) Patent Litigation&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Otezla&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt; ANDA Patent Litigation&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Amgen Inc. v. Sandoz Inc., et al.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;On September 28, 2021, consistent with its September 20, 2021 opinion and order, the U.S. District Court for the District of New Jersey (the New Jersey District Court) entered final judgment in favor of Amgen and against Zydus Pharmaceuticals (USA) Inc. (Zydus) with respect to claims 3 and 6 of U.S. Patent No. 7,427,638 (the &#x2019;638 Patent), claim 6 of U.S. Patent No. 8,455,536 (the &#x2019;536 Patent) and claims 2 and 27 of U.S. Patent No. 8,093,283 (the &#x2018;283 Patent); and final judgment in favor of Zydus and against Amgen with respect to claims 1 and 15 of U.S. Patent No. 7,893,101 (the &#x2018;101 Patent) and claims 2, 19 and 21 of U.S. Patent No. 10,092,541 (the &#x2019;541 Patent). The final judgment ordered that the effective date of any final approval by the U.S. Food and Drug Administration (FDA) of Zydus&#x2019;s ANDA must be after expiration of the three infringed patents (the &#x2019;638, &#x2019;536 and &#x2019;283 Patents) and any regulatory exclusivity to which Amgen may become entitled. The final judgment also includes an injunction prohibiting Zydus from making, using, offering to sell, or selling in the United States, or importing into the United States, Zydus&#x2019;s generic apremilast products during the term of the three infringed patents. &lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;On October 12, 2021, the New Jersey District Court also entered final judgment in favor of Amgen and against Sandoz Inc. (Sandoz) with respect to claims 3 and 6 of the &#x2019;638 Patent, claim 6 of the &#x2019;536 Patent and claims 1 and 15 of the &#x2019;101 Patent; and final judgment in favor of Sandoz and against Amgen with respect to claims 2, 19 and 21 of the &#x2019;541 Patent. The final judgment ordered that the effective date of any final approval by the FDA of Sandoz&#x2019;s ANDA must be after expiration of the three infringed patents (the &#x2019;638, &#x2019;536 and &#x2019;101 Patents) and any regulatory exclusivity to which Amgen may become entitled. The final judgment also includes an injunction prohibiting Sandoz from making, using, offering to sell, or selling in the United States, or importing into the United States, Sandoz&#x2019;s generic apremilast products during the term of the three infringed patents.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Zydus and Amgen filed notices of appeal to the U.S. Court of Appeals for the Federal Circuit (the Federal Circuit Court) on October 27, 2021 and October 28, 2021, respectively.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Sensipar&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;(cinacalcet) ANDA Patent Litigation&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Amgen Inc. v. Amneal Pharmaceuticals LLC, et al. (formerly, Amgen Inc. v. Aurobindo Pharma Ltd. et al.) &lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;On October 20, 2021, the U.S. District Court for the District of Delaware (the Delaware District Court) issued final judgment in favor of Piramal Healthcare UK Limited and Slate Run Pharmaceuticals LLC.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;ENBREL Patent Litigation&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Immunex Corporation, et al. v. Samsung Bioepis Co., Ltd.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;On November 2, 2021, Amgen and Samsung Bioepis Co., Ltd. (Bioepis), with the consent of Hoffmann-La Roche Inc. (Roche), jointly submitted to the New Jersey District Court a confidential stipulation and a form of final judgment and order of permanent injunction resolving the dispute between the parties and enjoining Bioepis from making, using, offering to sell, or selling within the United States, or importing into the United States, any product containing etanercept until the April 24, 2029 expiry of Roche&#x2019;s U.S. Patent No. 8,163,522.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Repatha&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt; Patent Litigation&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Patent Disputes in the International Region&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;National litigations in the United Kingdom, France, the Netherlands and Italy have been settled. In Germany, Sanofi-Aventis Deutschland GmbH and Regeneron Pharmaceuticals, Inc. have filed actions claiming they are entitled to damages arising from the provisional enforcement of an injunction against PRALUENT&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.47pt;font-weight:400;line-height:120%;position:relative;top:-3.48pt;vertical-align:baseline"&gt;&#xae; &lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;that was lifted after the European Patent Office Technical Board of Appeal&#x2019;s October 29, 2020 ruling that certain claims encompassing PRALUENT&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.47pt;font-weight:400;line-height:120%;position:relative;top:-3.48pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt; in Amgen&#x2019;s European Patent No. 2,215,124 were invalid.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;NEUPOGEN&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt; (filgrastim)/Neulasta&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline"&gt;&#xae;&lt;/span&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt; Patent Litigation&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Amgen Inc., et al. v. Pfizer Inc. et al.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;On September 8, 2021, pursuant to joint stipulation, the Delaware District Court dismissed the lawsuits regarding U.S. Patent Nos. 9,643,997 and 10,577,392.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:13.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Patent Trial and Appeal Board (PTAB) Challenge&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Apotex PTAB Challenge&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;On September 2, 2021, the Federal Circuit Court issued a remand to permit Amgen to request rehearing of the PTAB&#x2019;s final written decision holding that all claims of U.S. Patent No. 8.952,138 as unpatentable.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Pfizer PTAB Challenge&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;On February 10, 2021, Hospira, Inc. and Pfizer Inc. (collectively, Pfizer) filed a petition to institute inter partes review (IPR) proceeding at the U.S. Patent and Trademark Office (USPTO) of U.S. Patent No. 8,273,707 (the &#x2019;707 Patent), challenging claims of the &#x2019;707 Patent as unpatentable. Amgen&#x2019;s preliminary response was filed on May 18, 2021.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;On August 17, 2021, the PTAB of the USPTO granted Pfizer&#x2019;s petition to institute IPR of the &#x2019;707 Patent. On August 23, 2021, the PTAB issued the schedule for the proceeding, including oral argument (if requested) on May 18, 2022. &lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Breach of Contract Action&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Novartis Pharma AG v. Amgen Inc.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;On October 26, 2021, the U.S. District Court for the Southern District of New York held a status conference with the parties and set the dates for Novartis Pharma AG&#x2019;s (Novartis) opening brief for its motion for partial summary judgment on two claims, fraudulent inducement and negligent misrepresentation, to be due on January 14, 2022, Amgen&#x2019;s opposition to be due on February 14, 2022 and Novartis&#x2019; reply to be due on March 10, 2022. This motion, if granted, will not dispose of the entire case as other claims related to breach of contract remain pending.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;U.S. Tax Litigation&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"&gt;Amgen Inc. &amp;amp; Subsidiaries v. Commissioner of Internal Revenue&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;See Note 4, Income taxes, for discussion of the IRS tax dispute and the Company&#x2019;s petition in the U.S. Tax Court.&lt;/span&gt;&lt;/div&gt;</us-gaap:CommitmentsAndContingenciesDisclosureTextBlock>
    <us-gaap:GainContingencyPatentsFoundInfringedUponNumber
      contextRef="i2cc9eff2f67a40c98702116571cdb627_D20210928-20210928"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83MC9mcmFnOjZmMzVmMjIzNjJhNzQwNjliZWM5MjRhMGNmOTY0NjdmL3RleHRyZWdpb246NmYzNWYyMjM2MmE3NDA2OWJlYzkyNGEwY2Y5NjQ2N2ZfNzY5NjU4MTQzOTg5Mg_91efbe2e-7dc6-423c-b65d-167cbc96a344"
      unitRef="patent">3</us-gaap:GainContingencyPatentsFoundInfringedUponNumber>
    <us-gaap:GainContingencyPatentsFoundInfringedUponNumber
      contextRef="idaf73178159c45d5ba7f7dde88688204_D20211012-20211012"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83MC9mcmFnOjZmMzVmMjIzNjJhNzQwNjliZWM5MjRhMGNmOTY0NjdmL3RleHRyZWdpb246NmYzNWYyMjM2MmE3NDA2OWJlYzkyNGEwY2Y5NjQ2N2ZfNzY5NjU4MTQzOTg5Mw_e67f6a26-5a4c-4d5b-be8c-3deb0619eb95"
      unitRef="patent">3</us-gaap:GainContingencyPatentsFoundInfringedUponNumber>
    <us-gaap:GainContingencyPatentsFoundInfringedUponNumber
      contextRef="idaf73178159c45d5ba7f7dde88688204_D20211012-20211012"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83MC9mcmFnOjZmMzVmMjIzNjJhNzQwNjliZWM5MjRhMGNmOTY0NjdmL3RleHRyZWdpb246NmYzNWYyMjM2MmE3NDA2OWJlYzkyNGEwY2Y5NjQ2N2ZfNzY5NjU4MTQzOTg5NA_575302b2-7fca-40e9-a417-b6bfc9116c70"
      unitRef="patent">3</us-gaap:GainContingencyPatentsFoundInfringedUponNumber>
    <us-gaap:LossContingencyPendingClaimsNumber
      contextRef="i7e4af91b19174262910dae2ac9317e09_I20211026"
      decimals="INF"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83MC9mcmFnOjZmMzVmMjIzNjJhNzQwNjliZWM5MjRhMGNmOTY0NjdmL3RleHRyZWdpb246NmYzNWYyMjM2MmE3NDA2OWJlYzkyNGEwY2Y5NjQ2N2ZfODI0NjMzNzI1NDE0MQ_2741fd6e-ee32-49c1-8aa7-ec06f019bb04"
      unitRef="claim">2</us-gaap:LossContingencyPendingClaimsNumber>
    <us-gaap:SubsequentEventsTextBlock
      contextRef="i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83My9mcmFnOjlhYzgyOGNkN2E5ODQ2NzdiMDJiZjExNThmN2RjNGRhL3RleHRyZWdpb246OWFjODI4Y2Q3YTk4NDY3N2IwMmJmMTE1OGY3ZGM0ZGFfNDgy_0cdb7a59-3a78-4a60-a027-073e9f881323">Subsequent event&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;On October 19, 2021, Amgen completed its acquisition of Teneobio, Inc. (Teneobio), a privately held, clinical-stage biotechnology company developing a new class of biologics called heavy-chain only antibodies (HCAbs). Amgen acquired all outstanding shares in exchange for a $900&#160;million upfront payment, as well as future contingent milestone payments potentially worth up to an additional $1.6&#160;billion in cash upon the achievement of certain development and regulatory events.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The accounting impact of this acquisition and the results of operations for Teneobio will be included in our consolidated financial statements beginning in the fourth quarter of 2021. The initial accounting for this acquisition is incomplete, pending identification and measurement of the assets acquired and liabilities assumed.&lt;/span&gt;&lt;/div&gt;</us-gaap:SubsequentEventsTextBlock>
    <us-gaap:PaymentsToAcquireBusinessesGross
      contextRef="i7b7289e4de274a45a8d257b031b3ad23_D20211019-20211019"
      decimals="-6"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83My9mcmFnOjlhYzgyOGNkN2E5ODQ2NzdiMDJiZjExNThmN2RjNGRhL3RleHRyZWdpb246OWFjODI4Y2Q3YTk4NDY3N2IwMmJmMTE1OGY3ZGM0ZGFfNzY5NjU4MTM5NzcyNA_3a08b0d3-7b00-44a7-be29-94110bef1346"
      unitRef="usd">900000000</us-gaap:PaymentsToAcquireBusinessesGross>
    <us-gaap:BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh
      contextRef="i83f84ec51bef4ffe9c7bfc9f4c177613_I20211019"
      decimals="-8"
      id="id3VybDovL2RvY3MudjEvZG9jOjBiMmRkOTYxNTBlMzQwMjA4YTU3ZmFlYzIzZWMyZGE1L3NlYzowYjJkZDk2MTUwZTM0MDIwOGE1N2ZhZWMyM2VjMmRhNV83My9mcmFnOjlhYzgyOGNkN2E5ODQ2NzdiMDJiZjExNThmN2RjNGRhL3RleHRyZWdpb246OWFjODI4Y2Q3YTk4NDY3N2IwMmJmMTE1OGY3ZGM0ZGFfNzY5NjU4MTM5NzczOA_57620c29-635f-4eee-bdee-8640a7556438"
      unitRef="usd">1600000000</us-gaap:BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh>
</xbrl>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>11
<FILENAME>R1.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304056001928">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Cover Page - shares<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
<th class="th" colspan="1"></th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Oct. 28, 2021</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityInformationLineItems', window );"><strong>Entity Information [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_DocumentType', window );">Document Type</a></td>
<td class="text">10-Q<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_DocumentQuarterlyReport', window );">Document Quarterly Report</a></td>
<td class="text">true<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_DocumentPeriodEndDate', window );">Document Period End Date</a></td>
<td class="text">Sep. 30,  2021<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_DocumentTransitionReport', window );">Document Transition Report</a></td>
<td class="text">false<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityFileNumber', window );">Entity File Number</a></td>
<td class="text">001-37702<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityRegistrantName', window );">Entity Registrant Name</a></td>
<td class="text">Amgen Inc.<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityCentralIndexKey', window );">Entity Central Index Key</a></td>
<td class="text">0000318154<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_AmendmentFlag', window );">Amendment Flag</a></td>
<td class="text">false<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_DocumentFiscalYearFocus', window );">Document Fiscal Year Focus</a></td>
<td class="text">2021<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_DocumentFiscalPeriodFocus', window );">Document Fiscal Period Focus</a></td>
<td class="text">Q3<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_CurrentFiscalYearEndDate', window );">Current Fiscal Year End Date</a></td>
<td class="text">--12-31<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityIncorporationStateCountryCode', window );">Entity Incorporation, State or Country Code</a></td>
<td class="text">DE<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityTaxIdentificationNumber', window );">Entity Tax Identification Number</a></td>
<td class="text">95-3540776<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityAddressAddressLine1', window );">Entity Address, Address Line One</a></td>
<td class="text">One Amgen Center Drive<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityAddressCityOrTown', window );">Entity Address, City or Town</a></td>
<td class="text">Thousand Oaks<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityAddressStateOrProvince', window );">Entity Address, State or Province</a></td>
<td class="text">CA<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityAddressPostalZipCode', window );">Entity Address, Postal Zip Code</a></td>
<td class="text">91320-1799<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_CityAreaCode', window );">City Area Code</a></td>
<td class="text">805<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_LocalPhoneNumber', window );">Local Phone Number</a></td>
<td class="text">447-1000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityCurrentReportingStatus', window );">Entity Current Reporting Status</a></td>
<td class="text">Yes<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityInteractiveDataCurrent', window );">Entity Interactive Data Current</a></td>
<td class="text">Yes<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityFilerCategory', window );">Entity Filer Category</a></td>
<td class="text">Large Accelerated Filer<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntitySmallBusiness', window );">Entity Small Business</a></td>
<td class="text">false<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityEmergingGrowthCompany', window );">Entity Emerging Growth Company</a></td>
<td class="text">false<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityShellCompany', window );">Entity Shell Company</a></td>
<td class="text">false<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityCommonStockSharesOutstanding', window );">Entity Common Stock, Shares Outstanding</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">563,265,902<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityListingsExchangeAxis=exch_XNGS', window );">The NASDAQ Global Select Market [Member] | Common Stock [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityInformationLineItems', window );"><strong>Entity Information [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_Security12bTitle', window );">Title of 12(b) Security</a></td>
<td class="text">Common stock, $0.0001 par value<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_TradingSymbol', window );">Trading Symbol</a></td>
<td class="text">AMGN<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_SecurityExchangeName', window );">Security Exchange Name</a></td>
<td class="text">NASDAQ<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityListingsExchangeAxis=exch_XNGS', window );">The NASDAQ Global Select Market [Member] | 1.250% Senior Notes Due 2022 [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityInformationLineItems', window );"><strong>Entity Information [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_Security12bTitle', window );">Title of 12(b) Security</a></td>
<td class="text">1.250% Senior Notes due 2022<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_TradingSymbol', window );">Trading Symbol</a></td>
<td class="text">AMGN22<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_SecurityExchangeName', window );">Security Exchange Name</a></td>
<td class="text">NASDAQ<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityListingsExchangeAxis=exch_XNGS', window );">The NASDAQ Global Select Market [Member] | 2.00% Senior Notes Due 2026 [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityInformationLineItems', window );"><strong>Entity Information [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_Security12bTitle', window );">Title of 12(b) Security</a></td>
<td class="text">2.00% Senior Notes due 2026<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_TradingSymbol', window );">Trading Symbol</a></td>
<td class="text">AMGN26<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_SecurityExchangeName', window );">Security Exchange Name</a></td>
<td class="text">NASDAQ<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_AmendmentFlag">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the XBRL content amends previously-filed or accepted submission.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_AmendmentFlag</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_CityAreaCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Area code of city</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_CityAreaCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_CurrentFiscalYearEndDate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>End date of current fiscal year in the format --MM-DD.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_CurrentFiscalYearEndDate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:gMonthDayItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentFiscalPeriodFocus">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fiscal period values are FY, Q1, Q2, and Q3.  1st, 2nd and 3rd quarter 10-Q or 10-QT statements have value Q1, Q2, and Q3 respectively, with 10-K, 10-KT or other fiscal year statements having FY.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentFiscalPeriodFocus</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:fiscalPeriodItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentFiscalYearFocus">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>This is focus fiscal year of the document report in YYYY format. For a 2006 annual report, which may also provide financial information from prior periods, fiscal 2006 should be given as the fiscal year focus. Example: 2006.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentFiscalYearFocus</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:gYearItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentPeriodEndDate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>For the EDGAR submission types of Form 8-K: the date of the report, the date of the earliest event reported; for the EDGAR submission types of Form N-1A: the filing date; for all other submission types: the end of the reporting or transition period.  The format of the date is YYYY-MM-DD.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentPeriodEndDate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:dateItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentQuarterlyReport">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true only for a form used as an quarterly report.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Form 10-Q<br> -Number 240<br> -Section 308<br> -Subsection a<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentQuarterlyReport</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentTransitionReport">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true only for a form used as a transition report.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Forms 10-K, 10-Q, 20-F<br> -Number 240<br> -Section 13<br> -Subsection a-1<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentTransitionReport</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentType">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The type of document being provided (such as 10-K, 10-Q, 485BPOS, etc). The document type is limited to the same value as the supporting SEC submission type, or the word 'Other'.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentType</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:submissionTypeItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressAddressLine1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Address Line 1 such as Attn, Building Name, Street Name</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressAddressLine1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressCityOrTown">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Name of the City or Town</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressCityOrTown</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressPostalZipCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Code for the postal or zip code</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressPostalZipCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressStateOrProvince">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Name of the state or province.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressStateOrProvince</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:stateOrProvinceItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityCentralIndexKey">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>A unique 10-digit SEC-issued value to identify entities that have filed disclosures with the SEC. It is commonly abbreviated as CIK.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityCentralIndexKey</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:centralIndexKeyItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityCommonStockSharesOutstanding">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Indicate number of shares or other units outstanding of each of registrant's classes of capital or common stock or other ownership interests, if and as stated on cover of related periodic report. Where multiple classes or units exist define each class/interest by adding class of stock items such as Common Class A [Member], Common Class B [Member] or Partnership Interest [Member] onto the Instrument [Domain] of the Entity Listings, Instrument.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityCommonStockSharesOutstanding</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityCurrentReportingStatus">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Indicate 'Yes' or 'No' whether registrants (1) have filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that registrants were required to file such reports), and (2) have been subject to such filing requirements for the past 90 days. This information should be based on the registrant's current or most recent filing containing the related disclosure.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityCurrentReportingStatus</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:yesNoItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityEmergingGrowthCompany">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Indicate if registrant meets the emerging growth company criteria.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityEmergingGrowthCompany</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityFileNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Commission file number. The field allows up to 17 characters. The prefix may contain 1-3 digits, the sequence number may contain 1-8 digits, the optional suffix may contain 1-4 characters, and the fields are separated with a hyphen.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityFileNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:fileNumberItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityFilerCategory">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Indicate whether the registrant is one of the following: Large Accelerated Filer, Accelerated Filer, Non-accelerated Filer. Definitions of these categories are stated in Rule 12b-2 of the Exchange Act. This information should be based on the registrant's current or most recent filing containing the related disclosure.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityFilerCategory</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:filerCategoryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityIncorporationStateCountryCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Two-character EDGAR code representing the state or country of incorporation.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityIncorporationStateCountryCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:edgarStateCountryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityInformationLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityInformationLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityInteractiveDataCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit such files).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation S-T<br> -Number 232<br> -Section 405<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityInteractiveDataCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:yesNoItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityRegistrantName">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The exact name of the entity filing the report as specified in its charter, which is required by forms filed with the SEC.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityRegistrantName</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityShellCompany">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the registrant is a shell company as defined in Rule 12b-2 of the Exchange Act.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityShellCompany</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntitySmallBusiness">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Indicates that the company is a Smaller Reporting Company (SRC).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntitySmallBusiness</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityTaxIdentificationNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The Tax Identification Number (TIN), also known as an Employer Identification Number (EIN), is a unique 9-digit value assigned by the IRS.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityTaxIdentificationNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:employerIdItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_LocalPhoneNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Local phone number for entity.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_LocalPhoneNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_Security12bTitle">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Title of a 12(b) registered security.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_Security12bTitle</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:securityTitleItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_SecurityExchangeName">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Name of the Exchange on which a security is registered.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection d1-1<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_SecurityExchangeName</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:edgarExchangeCodeItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_TradingSymbol">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Trading symbol of an instrument as listed on an exchange.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_TradingSymbol</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:tradingSymbolItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityListingsExchangeAxis=exch_XNGS">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityListingsExchangeAxis=exch_XNGS</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementClassOfStockAxis=us-gaap_CommonStockMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementClassOfStockAxis=us-gaap_CommonStockMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementClassOfStockAxis=amgn_A1.250SeniorNotesDue2022Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementClassOfStockAxis=amgn_A1.250SeniorNotesDue2022Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementClassOfStockAxis=amgn_A2.00SeniorNotesDue2026Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementClassOfStockAxis=amgn_A2.00SeniorNotesDue2026Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>12
<FILENAME>R2.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304160574056">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Condensed Consolidated Statements of Comprehensive Income - USD ($)<br> $ in Millions</strong></div></th>
<th class="th" colspan="2">3 Months Ended</th>
<th class="th" colspan="2">9 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract', window );"><strong>Statement of Comprehensive Income [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income</a></td>
<td class="nump">$ 1,884<span></span>
</td>
<td class="nump">$ 2,021<span></span>
</td>
<td class="nump">$ 3,994<span></span>
</td>
<td class="nump">$ 5,649<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract', window );"><strong>Other comprehensive income (loss), net of reclassification adjustments and taxes:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent', window );">(Losses) gains on foreign currency translation</a></td>
<td class="num">(35)<span></span>
</td>
<td class="nump">14<span></span>
</td>
<td class="num">(60)<span></span>
</td>
<td class="num">(41)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent', window );">Gains (losses) on cash flow hedges</a></td>
<td class="nump">99<span></span>
</td>
<td class="num">(128)<span></span>
</td>
<td class="nump">241<span></span>
</td>
<td class="num">(305)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent', window );">(Losses) gains on available-for-sale securities</a></td>
<td class="num">(1)<span></span>
</td>
<td class="nump">1<span></span>
</td>
<td class="num">(1)<span></span>
</td>
<td class="num">(20)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent', window );">Other</a></td>
<td class="num">(3)<span></span>
</td>
<td class="num">(7)<span></span>
</td>
<td class="num">(3)<span></span>
</td>
<td class="num">(9)<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent', window );">Other comprehensive income (loss), net of taxes</a></td>
<td class="nump">60<span></span>
</td>
<td class="num">(120)<span></span>
</td>
<td class="nump">177<span></span>
</td>
<td class="num">(375)<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ComprehensiveIncomeNetOfTax', window );">Comprehensive income</a></td>
<td class="nump">$ 1,944<span></span>
</td>
<td class="nump">$ 1,901<span></span>
</td>
<td class="nump">$ 4,171<span></span>
</td>
<td class="nump">$ 5,274<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Other Comprehensive Income (Loss), Other Gains (Losses), Net of Tax, Portion Attributable to Parent</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ComprehensiveIncomeNetOfTax">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount after tax of increase (decrease) in equity from transactions and other events and circumstances from net income and other comprehensive income, attributable to parent entity. Excludes changes in equity resulting from investments by owners and distributions to owners.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(22))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(24))<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 5<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=d3e557-108580<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(26))<br> -URI http://asc.fasb.org/extlink&amp;oid=120399700&amp;loc=SL114874048-224260<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1B<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669625-108580<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1A<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669619-108580<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ComprehensiveIncomeNetOfTax</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetIncomeLoss">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(22))<br> -URI http://asc.fasb.org/extlink&amp;oid=120399700&amp;loc=SL114874048-224260<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22595-107794<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(18))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123482062&amp;loc=SL123482106-238011<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 50<br> -Paragraph 6<br> -URI http://asc.fasb.org/extlink&amp;oid=124431353&amp;loc=SL124452729-227067<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 8: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(20))<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br><br>Reference 9: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22499-107794<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 9<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22663-107794<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 17: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123596393&amp;loc=d3e14064-108612<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22583-107794<br><br>Reference 20: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 21: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=SL5780133-109256<br><br>Reference 22: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br><br>Reference 23: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22658-107794<br><br>Reference 24: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1A<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669619-108580<br><br>Reference 25: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 31<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8924-108599<br><br>Reference 26: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 27: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 28: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 205<br> -SubTopic 20<br> -Section 50<br> -Paragraph 7<br> -URI http://asc.fasb.org/extlink&amp;oid=109222650&amp;loc=SL51721683-107760<br><br>Reference 29: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1B<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669625-108580<br><br>Reference 30: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 31: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 32: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(B))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 33: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 34: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8906-108599<br><br>Reference 35: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetIncomeLoss</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount after tax and reclassification adjustments, of appreciation (loss) in value of unsold available-for-sale securities, attributable to parent entity. Excludes amounts related to other than temporary impairment (OTTI) loss.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1A<br> -Subparagraph (c)(3)<br> -URI http://asc.fasb.org/extlink&amp;oid=109239629&amp;loc=SL4573702-111684<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 45<br> -Paragraph 19<br> -URI http://asc.fasb.org/extlink&amp;oid=123454820&amp;loc=SL4569616-111683<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 45<br> -Paragraph 20<br> -URI http://asc.fasb.org/extlink&amp;oid=123454820&amp;loc=SL4569643-111683<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount after tax and reclassification adjustments of gain (loss) on foreign currency translation adjustments, foreign currency transactions designated and effective as economic hedges of a net investment in a foreign entity and intra-entity foreign currency transactions that are of a long-term-investment nature, attributable to parent entity.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 45<br> -Paragraph 20<br> -URI http://asc.fasb.org/extlink&amp;oid=123454820&amp;loc=SL4569643-111683<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1A<br> -Subparagraph (c)(3)<br> -URI http://asc.fasb.org/extlink&amp;oid=109239629&amp;loc=SL4573702-111684<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 45<br> -Paragraph 19<br> -URI http://asc.fasb.org/extlink&amp;oid=123454820&amp;loc=SL4569616-111683<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount, after tax and reclassification, of gain (loss) from derivative instrument designated and qualifying as cash flow hedge included in assessment of hedge effectiveness, attributable to parent.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 11<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=d3e637-108580<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount after tax of other comprehensive income (loss) attributable to parent entity.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1B<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669625-108580<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1A<br> -Subparagraph (c)(3)<br> -URI http://asc.fasb.org/extlink&amp;oid=109239629&amp;loc=SL4573702-111684<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 45<br> -Paragraph 20<br> -URI http://asc.fasb.org/extlink&amp;oid=123454820&amp;loc=SL4569643-111683<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1A<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669619-108580<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 45<br> -Paragraph 19<br> -URI http://asc.fasb.org/extlink&amp;oid=123454820&amp;loc=SL4569616-111683<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>13
<FILENAME>R3.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304055668920">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Condensed Consolidated Statements of Income - USD ($)<br> shares in Millions, $ in Millions</strong></div></th>
<th class="th" colspan="2">3 Months Ended</th>
<th class="th" colspan="2">9 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenuesAbstract', window );"><strong>Revenues:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">$ 6,706<span></span>
</td>
<td class="nump">$ 6,423<span></span>
</td>
<td class="nump">$ 19,133<span></span>
</td>
<td class="nump">$ 18,790<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CostsAndExpensesAbstract', window );"><strong>Operating expenses:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CostOfGoodsAndServicesSold', window );">Cost of sales</a></td>
<td class="nump">1,609<span></span>
</td>
<td class="nump">1,561<span></span>
</td>
<td class="nump">4,736<span></span>
</td>
<td class="nump">4,562<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost', window );">Research and development</a></td>
<td class="nump">1,422<span></span>
</td>
<td class="nump">1,062<span></span>
</td>
<td class="nump">3,471<span></span>
</td>
<td class="nump">2,978<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff', window );">Acquired in-process research and development</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="nump">1,505<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_SellingGeneralAndAdministrativeExpense', window );">Selling, general and administrative</a></td>
<td class="nump">1,305<span></span>
</td>
<td class="nump">1,346<span></span>
</td>
<td class="nump">3,943<span></span>
</td>
<td class="nump">3,957<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherGeneralExpense', window );">Other</a></td>
<td class="num">(8)<span></span>
</td>
<td class="nump">1<span></span>
</td>
<td class="nump">143<span></span>
</td>
<td class="nump">162<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CostsAndExpenses', window );">Total operating expenses</a></td>
<td class="nump">4,328<span></span>
</td>
<td class="nump">3,970<span></span>
</td>
<td class="nump">13,798<span></span>
</td>
<td class="nump">11,659<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OperatingIncomeLoss', window );">Operating income</a></td>
<td class="nump">2,378<span></span>
</td>
<td class="nump">2,453<span></span>
</td>
<td class="nump">5,335<span></span>
</td>
<td class="nump">7,131<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InterestExpenseDebt', window );">Interest expense, net</a></td>
<td class="num">(296)<span></span>
</td>
<td class="num">(302)<span></span>
</td>
<td class="num">(862)<span></span>
</td>
<td class="num">(944)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NonoperatingIncomeExpense', window );">Other income, net</a></td>
<td class="nump">73<span></span>
</td>
<td class="nump">55<span></span>
</td>
<td class="nump">97<span></span>
</td>
<td class="nump">69<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments', window );">Income before income taxes</a></td>
<td class="nump">2,155<span></span>
</td>
<td class="nump">2,206<span></span>
</td>
<td class="nump">4,570<span></span>
</td>
<td class="nump">6,256<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncomeTaxExpenseBenefit', window );">Provision for income taxes</a></td>
<td class="nump">271<span></span>
</td>
<td class="nump">185<span></span>
</td>
<td class="nump">576<span></span>
</td>
<td class="nump">607<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income</a></td>
<td class="nump">$ 1,884<span></span>
</td>
<td class="nump">$ 2,021<span></span>
</td>
<td class="nump">$ 3,994<span></span>
</td>
<td class="nump">$ 5,649<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EarningsPerShareAbstract', window );"><strong>Earnings per share:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EarningsPerShareBasic', window );">Basic (in usd per share)</a></td>
<td class="nump">$ 3.32<span></span>
</td>
<td class="nump">$ 3.45<span></span>
</td>
<td class="nump">$ 6.98<span></span>
</td>
<td class="nump">$ 9.61<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EarningsPerShareDiluted', window );">Diluted (in usd per share)</a></td>
<td class="nump">$ 3.31<span></span>
</td>
<td class="nump">$ 3.43<span></span>
</td>
<td class="nump">$ 6.93<span></span>
</td>
<td class="nump">$ 9.54<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract', window );"><strong>Shares used in calculation of earnings per share:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic', window );">Basic (in shares)</a></td>
<td class="nump">567<span></span>
</td>
<td class="nump">585<span></span>
</td>
<td class="nump">572<span></span>
</td>
<td class="nump">588<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding', window );">Diluted (in shares)</a></td>
<td class="nump">570<span></span>
</td>
<td class="nump">589<span></span>
</td>
<td class="nump">576<span></span>
</td>
<td class="nump">592<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=us-gaap_ProductMember', window );">Product sales [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenuesAbstract', window );"><strong>Revenues:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">$ 6,320<span></span>
</td>
<td class="nump">$ 6,104<span></span>
</td>
<td class="nump">$ 18,026<span></span>
</td>
<td class="nump">$ 17,906<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=us-gaap_ProductAndServiceOtherMember', window );">Other revenues [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenuesAbstract', window );"><strong>Revenues:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">$ 386<span></span>
</td>
<td class="nump">$ 319<span></span>
</td>
<td class="nump">$ 1,107<span></span>
</td>
<td class="nump">$ 884<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CostOfGoodsAndServicesSold">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The aggregate costs related to goods produced and sold and services rendered by an entity during the reporting period. This excludes costs incurred during the reporting period related to financial services rendered and other revenue generating activities.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 924<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB Topic 11.L)<br> -URI http://asc.fasb.org/extlink&amp;oid=6472922&amp;loc=d3e499488-122856<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03.2(a),(d))<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CostOfGoodsAndServicesSold</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CostsAndExpenses">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Total costs of sales and operating expenses for the period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03)<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CostsAndExpenses</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CostsAndExpensesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CostsAndExpensesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EarningsPerShareAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EarningsPerShareAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EarningsPerShareBasic">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The amount of net income (loss) for the period per each share of common stock or unit outstanding during the reporting period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (e)(4)<br> -URI http://asc.fasb.org/extlink&amp;oid=123482062&amp;loc=SL123482106-238011<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22583-107794<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=d3e1448-109256<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22595-107794<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 7<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=d3e1337-109256<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123482062&amp;loc=SL123482106-238011<br><br>Reference 9: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 55<br> -Paragraph 52<br> -URI http://asc.fasb.org/extlink&amp;oid=125512782&amp;loc=d3e4984-109258<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(23))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 55<br> -Paragraph 15<br> -URI http://asc.fasb.org/extlink&amp;oid=125512782&amp;loc=d3e3842-109258<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 7<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22644-107794<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124432515&amp;loc=d3e3550-109257<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(25))<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=d3e1252-109256<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=SL5780133-109256<br><br>Reference 17: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(27))<br> -URI http://asc.fasb.org/extlink&amp;oid=120399700&amp;loc=SL114874048-224260<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EarningsPerShareBasic</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EarningsPerShareDiluted">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The amount of net income (loss) for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 55<br> -Paragraph 52<br> -URI http://asc.fasb.org/extlink&amp;oid=125512782&amp;loc=d3e4984-109258<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 7<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22644-107794<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 55<br> -Paragraph 15<br> -URI http://asc.fasb.org/extlink&amp;oid=125512782&amp;loc=d3e3842-109258<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=d3e1252-109256<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22595-107794<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22583-107794<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=SL5780133-109256<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123482062&amp;loc=SL123482106-238011<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(27))<br> -URI http://asc.fasb.org/extlink&amp;oid=120399700&amp;loc=SL114874048-224260<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124432515&amp;loc=d3e3550-109257<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(23))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 7<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=d3e1337-109256<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (e)(4)<br> -URI http://asc.fasb.org/extlink&amp;oid=123482062&amp;loc=SL123482106-238011<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(25))<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EarningsPerShareDiluted</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of income (loss) from continuing operations before deduction of income tax expense (benefit) and income (loss) attributable to noncontrolling interest, and addition of income (loss) from equity method investments.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8906-108599<br><br>Reference 4: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 31<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8924-108599<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxExpenseBenefit">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB TOPIC 6.I.7)<br> -URI http://asc.fasb.org/extlink&amp;oid=122134291&amp;loc=d3e330036-122817<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section 50<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=121826272&amp;loc=d3e32672-109319<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -Subparagraph (h)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(h))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 9<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22663-107794<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 20<br> -Section 45<br> -Paragraph 2<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123586238&amp;loc=d3e38679-109324<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(9))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22658-107794<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxExpenseBenefit</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InterestExpenseDebt">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of the cost of borrowed funds accounted for as interest expense for debt.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 6<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466204&amp;loc=SL6036836-161870<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03.8)<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br><br>Reference 3: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69F<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495745-112612<br><br>Reference 4: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69E<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495743-112612<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1F<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495355-112611<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InterestExpenseDebt</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetIncomeLoss">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(22))<br> -URI http://asc.fasb.org/extlink&amp;oid=120399700&amp;loc=SL114874048-224260<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22595-107794<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(18))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123482062&amp;loc=SL123482106-238011<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 50<br> -Paragraph 6<br> -URI http://asc.fasb.org/extlink&amp;oid=124431353&amp;loc=SL124452729-227067<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 8: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(20))<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br><br>Reference 9: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22499-107794<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 9<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22663-107794<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 17: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123596393&amp;loc=d3e14064-108612<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22583-107794<br><br>Reference 20: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 21: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=SL5780133-109256<br><br>Reference 22: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br><br>Reference 23: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22658-107794<br><br>Reference 24: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1A<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669619-108580<br><br>Reference 25: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 31<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8924-108599<br><br>Reference 26: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 27: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 28: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 205<br> -SubTopic 20<br> -Section 50<br> -Paragraph 7<br> -URI http://asc.fasb.org/extlink&amp;oid=109222650&amp;loc=SL51721683-107760<br><br>Reference 29: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1B<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669625-108580<br><br>Reference 30: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 31: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 32: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(B))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 33: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 34: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8906-108599<br><br>Reference 35: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetIncomeLoss</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NonoperatingIncomeExpense">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The aggregate amount of income or expense from ancillary business-related activities (that is to say, excluding major activities considered part of the normal operations of the business).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03.7)<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NonoperatingIncomeExpense</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OperatingIncomeLoss">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The net result for the period of deducting operating expenses from operating revenues.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 31<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8924-108599<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8906-108599<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OperatingIncomeLoss</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherGeneralExpense">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of general expenses not normally included in Other Operating Costs and Expenses.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03.6)<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherGeneralExpense</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The amount of the write-off for research and development assets that were acquired in a transaction other than a business combination.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16265-109275<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The costs incurred in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, excluding in-process research and development acquired in a business combination consummated during the period. Excludes software research and development, which has a separate concept.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 730<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=6420194&amp;loc=d3e21568-108373<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8906-108599<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 40<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e9031-108599<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 41<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e9038-108599<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130543-203045<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 42<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e9054-108599<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 5<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130545-203045<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 924<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB Topic 11.L)<br> -URI http://asc.fasb.org/extlink&amp;oid=6472922&amp;loc=d3e499488-122856<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_RevenuesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_RevenuesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SellingGeneralAndAdministrativeExpense">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The aggregate total costs related to selling a firm's product and services, as well as all other general and administrative expenses. Direct selling expenses (for example, credit, warranty, and advertising) are expenses that can be directly linked to the sale of specific products. Indirect selling expenses are expenses that cannot be directly linked to the sale of specific products, for example telephone expenses, Internet, and postal charges. General and administrative expenses include salaries of non-sales personnel, rent, utilities, communication, etc.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03.4)<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SellingGeneralAndAdministrativeExpense</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The average number of shares or units issued and outstanding that are used in calculating diluted EPS or earnings per unit (EPU), determined based on the timing of issuance of shares or units in the period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124432515&amp;loc=d3e3550-109257<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 16<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=d3e1505-109256<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Number of [basic] shares or units, after adjustment for contingently issuable shares or units and other shares or units not deemed outstanding, determined by relating the portion of time within a reporting period that common shares or units have been outstanding to the total time in that period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124432515&amp;loc=d3e3550-109257<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=d3e1448-109256<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_WeightedAverageNumberOfSharesOutstandingBasic</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=us-gaap_ProductMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=us-gaap_ProductMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=us-gaap_ProductAndServiceOtherMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=us-gaap_ProductAndServiceOtherMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>14
<FILENAME>R4.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304056144376">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Condensed Consolidated Balance Sheets - USD ($)<br> $ in Millions</strong></div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsCurrentAbstract', window );"><strong>Current assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CashAndCashEquivalentsAtCarryingValue', window );">Cash and cash equivalents</a></td>
<td class="nump">$ 11,969<span></span>
</td>
<td class="nump">$ 6,266<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent', window );">Marketable securities</a></td>
<td class="nump">952<span></span>
</td>
<td class="nump">4,381<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AccountsReceivableNetCurrent', window );">Trade receivables, net</a></td>
<td class="nump">4,765<span></span>
</td>
<td class="nump">4,525<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InventoryNet', window );">Inventories</a></td>
<td class="nump">4,152<span></span>
</td>
<td class="nump">3,893<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherAssetsCurrent', window );">Other current assets</a></td>
<td class="nump">2,542<span></span>
</td>
<td class="nump">2,079<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsCurrent', window );">Total current assets</a></td>
<td class="nump">24,380<span></span>
</td>
<td class="nump">21,144<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_PropertyPlantAndEquipmentNet', window );">Property, plant and equipment, net</a></td>
<td class="nump">4,982<span></span>
</td>
<td class="nump">4,889<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IntangibleAssetsNetExcludingGoodwill', window );">Intangible assets, net</a></td>
<td class="nump">14,659<span></span>
</td>
<td class="nump">16,587<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_Goodwill', window );">Goodwill</a></td>
<td class="nump">14,665<span></span>
</td>
<td class="nump">14,689<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherAssetsNoncurrent', window );">Other noncurrent assets</a></td>
<td class="nump">6,307<span></span>
</td>
<td class="nump">5,639<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_Assets', window );">Total assets</a></td>
<td class="nump">64,993<span></span>
</td>
<td class="nump">62,948<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LiabilitiesCurrentAbstract', window );"><strong>Current liabilities:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AccountsPayableCurrent', window );">Accounts payable</a></td>
<td class="nump">1,171<span></span>
</td>
<td class="nump">1,421<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AccruedLiabilitiesCurrent', window );">Accrued liabilities</a></td>
<td class="nump">9,383<span></span>
</td>
<td class="nump">10,141<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongTermDebtCurrent', window );">Current portion of long-term debt</a></td>
<td class="nump">4,288<span></span>
</td>
<td class="nump">91<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LiabilitiesCurrent', window );">Total current liabilities</a></td>
<td class="nump">14,842<span></span>
</td>
<td class="nump">11,653<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongTermDebtNoncurrent', window );">Long-term debt</a></td>
<td class="nump">33,291<span></span>
</td>
<td class="nump">32,895<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent', window );">Long-term tax liabilities</a></td>
<td class="nump">6,483<span></span>
</td>
<td class="nump">6,968<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherLiabilitiesNoncurrent', window );">Other noncurrent liabilities</a></td>
<td class="nump">2,160<span></span>
</td>
<td class="nump">2,023<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommitmentsAndContingencies', window );">Contingencies and commitments</a></td>
<td class="text"> <span></span>
</td>
<td class="text"> <span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquityAbstract', window );"><strong>Stockholders&#8217; equity:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStocksIncludingAdditionalPaidInCapital', window );">Common stock and additional paid-in capital; $0.0001 par value; 2,750.0 shares authorized; outstanding&#8212;565.0 shares in 2021 and 578.3 shares in 2020</a></td>
<td class="nump">31,989<span></span>
</td>
<td class="nump">31,802<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RetainedEarningsAccumulatedDeficit', window );">Accumulated deficit</a></td>
<td class="num">(22,964)<span></span>
</td>
<td class="num">(21,408)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax', window );">Accumulated other comprehensive loss</a></td>
<td class="num">(808)<span></span>
</td>
<td class="num">(985)<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Total stockholders&#8217; equity</a></td>
<td class="nump">8,217<span></span>
</td>
<td class="nump">9,409<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LiabilitiesAndStockholdersEquity', window );">Total liabilities and stockholders&#8217; equity</a></td>
<td class="nump">$ 64,993<span></span>
</td>
<td class="nump">$ 62,948<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccountsPayableCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Carrying value as of the balance sheet date of liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.19(a))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccountsPayableCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccountsReceivableNetCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount, after allowance for credit loss, of right to consideration from customer for product sold and service rendered in normal course of business, classified as current.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 310<br> -SubTopic 10<br> -Section 45<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=124259787&amp;loc=d3e4428-111522<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(3))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 3: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=124098289&amp;loc=d3e6676-107765<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 310<br> -SubTopic 10<br> -Section 45<br> -Paragraph 9<br> -URI http://asc.fasb.org/extlink&amp;oid=124259787&amp;loc=d3e4531-111522<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccountsReceivableNetCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccruedLiabilitiesCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.20)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccruedLiabilitiesCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Accumulated change in equity from transactions and other events and circumstances from non-owner sources, net of tax effect, at period end. Excludes Net Income (Loss), and accumulated changes in equity from transactions resulting from investments by owners and distributions to owners. Includes foreign currency translation items, certain pension adjustments, unrealized gains and losses on certain investments in debt and equity securities, other than temporary impairment (OTTI) losses related to factors other than credit losses on available-for-sale and held-to-maturity debt securities that an entity does not intend to sell and it is not more likely than not that the entity will be required to sell before recovery of the amortized cost basis, as well as changes in the fair value of derivatives related to the effective portion of a designated cash flow hedge.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(30)(a)(4))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 11<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=d3e637-108580<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(a)(23)(a)(3))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400017&amp;loc=d3e572229-122910<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 14A<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669686-108580<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 40<br> -Section 65<br> -Paragraph 2<br> -Subparagraph (h)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=124501264&amp;loc=SL117420844-207641<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 40<br> -Section 65<br> -Paragraph 2<br> -Subparagraph (g)(2)(ii)<br> -URI http://asc.fasb.org/extlink&amp;oid=124501264&amp;loc=SL117420844-207641<br><br>Reference 7: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 14<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=d3e681-108580<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_Assets">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Sum of the carrying amounts as of the balance sheet date of all assets that are recognized. Assets are probable future economic benefits obtained or controlled by an entity as a result of past transactions or events.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03(11))<br> -URI http://asc.fasb.org/extlink&amp;oid=120398452&amp;loc=d3e534808-122878<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(a)(12))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400017&amp;loc=d3e572229-122910<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 8: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 50<br> -Paragraph 7<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124433192&amp;loc=SL2890621-112765<br><br>Reference 9: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 14: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123596393&amp;loc=d3e14064-108612<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(B))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 17: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (bb)<br> -URI http://asc.fasb.org/extlink&amp;oid=123419778&amp;loc=d3e5710-111685<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 45<br> -Paragraph 25<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=116870748&amp;loc=SL6758485-165988<br><br>Reference 20: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 21: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 22: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br><br>Reference 23: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8906-108599<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_Assets</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AssetsCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Sum of the carrying amounts as of the balance sheet date of all assets that are expected to be realized in cash, sold, or consumed within one year (or the normal operating cycle, if longer). Assets are probable future economic benefits obtained or controlled by an entity as a result of past transactions or events.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section 45<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=124098289&amp;loc=d3e6801-107765<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br><br>Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 50<br> -Paragraph 7<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124433192&amp;loc=SL2890621-112765<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.9)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 8: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123596393&amp;loc=d3e14064-108612<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 45<br> -Paragraph 25<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=116870748&amp;loc=SL6758485-165988<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(B))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br><br>Reference 15: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 17: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (bb)<br> -URI http://asc.fasb.org/extlink&amp;oid=123419778&amp;loc=d3e5710-111685<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 20: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=124098289&amp;loc=d3e6676-107765<br><br>Reference 21: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AssetsCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AssetsCurrentAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AssetsCurrentAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), classified as current.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 326<br> -SubTopic 30<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=124258926&amp;loc=SL82898722-210454<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 45<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=124260329&amp;loc=d3e26626-111562<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CashAndCashEquivalentsAtCarryingValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3044-108585<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124098289&amp;loc=d3e6676-107765<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.1)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CashAndCashEquivalentsAtCarryingValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommitmentsAndContingencies">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Represents the caption on the face of the balance sheet to indicate that the entity has entered into (1) purchase or supply arrangements that will require expending a portion of its resources to meet the terms thereof, and (2) is exposed to potential losses or, less frequently, gains, arising from (a) possible claims against a company's resources due to future performance under contract terms, and (b) possible losses or likely gains from uncertainties that will ultimately be resolved when one or more future events that are deemed likely to occur do occur or fail to occur.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.25)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03.(a),19)<br> -URI http://asc.fasb.org/extlink&amp;oid=120400017&amp;loc=d3e572229-122910<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03.17)<br> -URI http://asc.fasb.org/extlink&amp;oid=120398452&amp;loc=d3e534808-122878<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 450<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=121557415&amp;loc=d3e14326-108349<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommitmentsAndContingencies</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommonStocksIncludingAdditionalPaidInCapital">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of par value plus amounts in excess of par value or issuance value for common stock issued.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(30)(a)(1))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -URI http://asc.fasb.org/extlink&amp;oid=120397183&amp;loc=d3e187085-122770<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommonStocksIncludingAdditionalPaidInCapital</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_Goodwill">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount after accumulated impairment loss of an asset representing future economic benefits arising from other assets acquired in a business combination that are not individually identified and separately recognized.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03(10)(1))<br> -URI http://asc.fasb.org/extlink&amp;oid=120398452&amp;loc=d3e534808-122878<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 20<br> -Section 45<br> -Paragraph 5<br> -URI http://asc.fasb.org/extlink&amp;oid=120320667&amp;loc=SL49117168-202975<br><br>Reference 3: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 20<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=99380562&amp;loc=d3e13770-109266<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_Goodwill</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IntangibleAssetsNetExcludingGoodwill">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Sum of the carrying amounts of all intangible assets, excluding goodwill, as of the balance sheet date, net of accumulated amortization and impairment charges.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 2<br> -Subparagraph ((a)(1),(b))<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16323-109275<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=6388964&amp;loc=d3e16212-109274<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IntangibleAssetsNetExcludingGoodwill</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InventoryNet">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount after valuation and LIFO reserves of inventory expected to be sold, or consumed within one year or operating cycle, if longer.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124098289&amp;loc=d3e6676-107765<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.6(a))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InventoryNet</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LiabilitiesAndStockholdersEquity">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of liabilities and equity items, including the portion of equity attributable to noncontrolling interests, if any.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03(23))<br> -URI http://asc.fasb.org/extlink&amp;oid=120398452&amp;loc=d3e534808-122878<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(a)(25))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400017&amp;loc=d3e572229-122910<br><br>Reference 5: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(32))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 7: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123596393&amp;loc=d3e14064-108612<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LiabilitiesAndStockholdersEquity</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LiabilitiesCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Total obligations incurred as part of normal operations that are expected to be paid during the following twelve months or within one business cycle, if longer.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br><br>Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 50<br> -Paragraph 7<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124433192&amp;loc=SL2890621-112765<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 4: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 50<br> -Paragraph 7<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124433192&amp;loc=SL2890621-112765<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 45<br> -Paragraph 25<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=116870748&amp;loc=SL6758485-165988<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 7: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123419778&amp;loc=d3e5710-111685<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(B))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (bb)<br> -URI http://asc.fasb.org/extlink&amp;oid=123419778&amp;loc=d3e5710-111685<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 17: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123596393&amp;loc=d3e14064-108612<br><br>Reference 20: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.21)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LiabilitiesCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LiabilitiesCurrentAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LiabilitiesCurrentAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount recognized for uncertainty in income taxes classified as noncurrent.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.24)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LiabilityForUncertainTaxPositionsNoncurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LongTermDebtCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount, after unamortized (discount) premium and debt issuance costs, of long-term debt, classified as current. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.19,20)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LongTermDebtCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LongTermDebtNoncurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount after unamortized (discount) premium and debt issuance costs of long-term debt classified as noncurrent and excluding amounts to be repaid within one year or the normal operating cycle, if longer. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.22)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LongTermDebtNoncurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherAssetsCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of current assets classified as other.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.8)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherAssetsCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherAssetsNoncurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of noncurrent assets classified as other.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.17)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherAssetsNoncurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherLiabilitiesNoncurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of liabilities classified as other, due after one year or the normal operating cycle, if longer.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.24)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherLiabilitiesNoncurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PropertyPlantAndEquipmentNet">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount after accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business to produce goods and services and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(14))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 360<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=6391035&amp;loc=d3e2868-110229<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(a)(8))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400017&amp;loc=d3e572229-122910<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 360<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=124429447&amp;loc=SL124453093-239630<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(13))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 6: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PropertyPlantAndEquipmentNet</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_RetainedEarningsAccumulatedDeficit">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The cumulative amount of the reporting entity's undistributed earnings or deficit.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(30)(a)(3))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 10<br> -Section 65<br> -Paragraph 15<br> -Subparagraph (g)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=121322162&amp;loc=SL121327923-165333<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(a)(23)(a)(4))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400017&amp;loc=d3e572229-122910<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 40<br> -Section 65<br> -Paragraph 2<br> -Subparagraph (h)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=124501264&amp;loc=SL117420844-207641<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -URI http://asc.fasb.org/extlink&amp;oid=120397183&amp;loc=d3e187085-122770<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 40<br> -Section 65<br> -Paragraph 2<br> -Subparagraph (g)(2)(i)<br> -URI http://asc.fasb.org/extlink&amp;oid=124501264&amp;loc=SL117420844-207641<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_RetainedEarningsAccumulatedDeficit</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockholdersEquity">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Total of all stockholders' equity (deficit) items, net of receivables from officers, directors, owners, and affiliates of the entity which are attributable to the parent. The amount of the economic entity's stockholders' equity attributable to the parent excludes the amount of stockholders' equity which is allocable to that ownership interest in subsidiary equity which is not attributable to the parent (noncontrolling interest, minority interest). This excludes temporary equity and is sometimes called permanent equity.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 310<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SAB Topic 4.E)<br> -URI http://asc.fasb.org/extlink&amp;oid=122038336&amp;loc=d3e74512-122707<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(31))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(30))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 7: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123596393&amp;loc=d3e14064-108612<br><br>Reference 8: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockholdersEquity</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockholdersEquityAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockholdersEquityAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>15
<FILENAME>R5.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304144973896">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Condensed Consolidated Balance Sheets (Parenthetical) - $ / shares<br> shares in Millions</strong></div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StatementOfFinancialPositionAbstract', window );"><strong>Statement of Financial Position [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockParOrStatedValuePerShare', window );">Common stock and additional paid-in capital, par value (in usd per share)</a></td>
<td class="nump">$ 0.0001<span></span>
</td>
<td class="nump">$ 0.0001<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesAuthorized', window );">Common stock and additional paid-in capital, shares authorized</a></td>
<td class="nump">2,750.0<span></span>
</td>
<td class="nump">2,750.0<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Common stock and additional paid-in capital, shares outstanding</a></td>
<td class="nump">565.0<span></span>
</td>
<td class="nump">578.3<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommonStockParOrStatedValuePerShare">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Face amount or stated value per share of common stock.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommonStockParOrStatedValuePerShare</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommonStockSharesAuthorized">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The maximum number of common shares permitted to be issued by an entity's charter and bylaws.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommonStockSharesAuthorized</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommonStockSharesOutstanding">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Number of shares of common stock outstanding. Common stock represent the ownership interest in a corporation.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=d3e21463-112644<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommonStockSharesOutstanding</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementOfFinancialPositionAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementOfFinancialPositionAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>16
<FILENAME>R6.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304049128184">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Condensed Consolidated Statements of Stockholders' Equity - USD ($)<br> shares in Millions, $ in Millions</strong></div></th>
<th class="th"><div>Total</div></th>
<th class="th"><div>Cumulative effect of changes in accounting principles, net of tax</div></th>
<th class="th"><div>Number of shares of common stock [Member]</div></th>
<th class="th"><div>Common stock and additional paid-in capital [Member]</div></th>
<th class="th"><div>Accumulated deficit [Member]</div></th>
<th class="th">
<div>Accumulated deficit [Member] </div>
<div>Cumulative effect of changes in accounting principles, net of tax</div>
</th>
<th class="th"><div>Accumulated other comprehensive loss [Member]</div></th>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Beginning Balance, Shares at Dec. 31, 2019</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">591.4<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of beginning of period at Dec. 31, 2019</a></td>
<td class="nump">$ 9,673<span></span>
</td>
<td class="num">$ (2)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 31,531<span></span>
</td>
<td class="num">$ (21,330)<span></span>
</td>
<td class="num">$ (2)<span></span>
</td>
<td class="num">$ (528)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward', window );"><strong>Increase (Decrease) in Stockholders' Equity [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income for basic and diluted EPS</a></td>
<td class="nump">1,825<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1,825<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossNetOfTax', window );">Other comprehensive income (loss), net of taxes</a></td>
<td class="num">(134)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(134)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DividendsCommonStockCash', window );">Dividends declared on common stock</a></td>
<td class="num">(938)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(938)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation', window );">Issuance of common stock in connection with the Company&#8217;s equity award programs, Shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0.9<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation', window );">Issuance of common stock in connection with the Company&#8217;s equity award programs</a></td>
<td class="nump">10<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">10<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue', window );">Stock-based compensation expense</a></td>
<td class="nump">52<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">52<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet', window );">Tax impact related to employee stock-based compensation expense</a></td>
<td class="num">(68)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(68)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares', window );">Repurchases of common stock, Shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(4.3)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue', window );">Repurchases of common stock</a></td>
<td class="num">(933)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(933)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Ending Balance, Shares at Mar. 31, 2020</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">588.0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of end of period at Mar. 31, 2020</a></td>
<td class="nump">9,485<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">31,525<span></span>
</td>
<td class="num">(21,378)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(662)<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Beginning Balance, Shares at Dec. 31, 2019</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">591.4<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of beginning of period at Dec. 31, 2019</a></td>
<td class="nump">9,673<span></span>
</td>
<td class="num">$ (2)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">31,531<span></span>
</td>
<td class="num">(21,330)<span></span>
</td>
<td class="num">$ (2)<span></span>
</td>
<td class="num">(528)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward', window );"><strong>Increase (Decrease) in Stockholders' Equity [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income for basic and diluted EPS</a></td>
<td class="nump">5,649<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Ending Balance, Shares at Sep. 30, 2020</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">583.5<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of end of period at Sep. 30, 2020</a></td>
<td class="nump">10,959<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">31,713<span></span>
</td>
<td class="num">(19,851)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(903)<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Beginning Balance, Shares at Mar. 31, 2020</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">588.0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of beginning of period at Mar. 31, 2020</a></td>
<td class="nump">9,485<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">31,525<span></span>
</td>
<td class="num">(21,378)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(662)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward', window );"><strong>Increase (Decrease) in Stockholders' Equity [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income for basic and diluted EPS</a></td>
<td class="nump">1,803<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1,803<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossNetOfTax', window );">Other comprehensive income (loss), net of taxes</a></td>
<td class="num">(121)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(121)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation', window );">Issuance of common stock in connection with the Company&#8217;s equity award programs, Shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1.0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation', window );">Issuance of common stock in connection with the Company&#8217;s equity award programs</a></td>
<td class="nump">65<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">65<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue', window );">Stock-based compensation expense</a></td>
<td class="nump">101<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">101<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet', window );">Tax impact related to employee stock-based compensation expense</a></td>
<td class="num">(81)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(81)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares', window );">Repurchases of common stock, Shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(2.6)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue', window );">Repurchases of common stock</a></td>
<td class="num">(591)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(591)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquityOther', window );">Other</a></td>
<td class="num">(2)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(2)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Ending Balance, Shares at Jun. 30, 2020</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">586.4<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of end of period at Jun. 30, 2020</a></td>
<td class="nump">10,659<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">31,610<span></span>
</td>
<td class="num">(20,168)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(783)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward', window );"><strong>Increase (Decrease) in Stockholders' Equity [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income for basic and diluted EPS</a></td>
<td class="nump">2,021<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">2,021<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossNetOfTax', window );">Other comprehensive income (loss), net of taxes</a></td>
<td class="num">(120)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(120)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DividendsCommonStockCash', window );">Dividends declared on common stock</a></td>
<td class="num">(952)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(952)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation', window );">Issuance of common stock in connection with the Company&#8217;s equity award programs, Shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0.1<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation', window );">Issuance of common stock in connection with the Company&#8217;s equity award programs</a></td>
<td class="nump">5<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">5<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue', window );">Stock-based compensation expense</a></td>
<td class="nump">109<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">109<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet', window );">Tax impact related to employee stock-based compensation expense</a></td>
<td class="num">(11)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(11)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares', window );">Repurchases of common stock, Shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(3.0)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue', window );">Repurchases of common stock</a></td>
<td class="num">(752)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(752)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Ending Balance, Shares at Sep. 30, 2020</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">583.5<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of end of period at Sep. 30, 2020</a></td>
<td class="nump">$ 10,959<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">31,713<span></span>
</td>
<td class="num">(19,851)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(903)<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Beginning Balance, Shares at Dec. 31, 2020</a></td>
<td class="nump">578.3<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">578.3<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of beginning of period at Dec. 31, 2020</a></td>
<td class="nump">$ 9,409<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">31,802<span></span>
</td>
<td class="num">(21,408)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(985)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward', window );"><strong>Increase (Decrease) in Stockholders' Equity [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income for basic and diluted EPS</a></td>
<td class="nump">1,646<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1,646<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossNetOfTax', window );">Other comprehensive income (loss), net of taxes</a></td>
<td class="nump">152<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">152<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DividendsCommonStockCash', window );">Dividends declared on common stock</a></td>
<td class="num">(1,012)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(1,012)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation', window );">Issuance of common stock in connection with the Company&#8217;s equity award programs, Shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0.7<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation', window );">Issuance of common stock in connection with the Company&#8217;s equity award programs</a></td>
<td class="nump">6<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">6<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue', window );">Stock-based compensation expense</a></td>
<td class="nump">57<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">57<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet', window );">Tax impact related to employee stock-based compensation expense</a></td>
<td class="num">(59)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(59)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares', window );">Repurchases of common stock, Shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(3.7)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue', window );">Repurchases of common stock</a></td>
<td class="num">(865)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(865)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Ending Balance, Shares at Mar. 31, 2021</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">575.3<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of end of period at Mar. 31, 2021</a></td>
<td class="nump">$ 9,334<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">31,806<span></span>
</td>
<td class="num">(21,639)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(833)<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Beginning Balance, Shares at Dec. 31, 2020</a></td>
<td class="nump">578.3<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">578.3<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of beginning of period at Dec. 31, 2020</a></td>
<td class="nump">$ 9,409<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">31,802<span></span>
</td>
<td class="num">(21,408)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(985)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward', window );"><strong>Increase (Decrease) in Stockholders' Equity [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income for basic and diluted EPS</a></td>
<td class="nump">$ 3,994<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Ending Balance, Shares at Sep. 30, 2021</a></td>
<td class="nump">565.0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">565.0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of end of period at Sep. 30, 2021</a></td>
<td class="nump">$ 8,217<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">31,989<span></span>
</td>
<td class="num">(22,964)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(808)<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Beginning Balance, Shares at Mar. 31, 2021</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">575.3<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of beginning of period at Mar. 31, 2021</a></td>
<td class="nump">9,334<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">31,806<span></span>
</td>
<td class="num">(21,639)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(833)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward', window );"><strong>Increase (Decrease) in Stockholders' Equity [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income for basic and diluted EPS</a></td>
<td class="nump">464<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">464<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossNetOfTax', window );">Other comprehensive income (loss), net of taxes</a></td>
<td class="num">(35)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(35)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation', window );">Issuance of common stock in connection with the Company&#8217;s equity award programs, Shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0.8<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation', window );">Issuance of common stock in connection with the Company&#8217;s equity award programs</a></td>
<td class="nump">47<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">47<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue', window );">Stock-based compensation expense</a></td>
<td class="nump">100<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">100<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet', window );">Tax impact related to employee stock-based compensation expense</a></td>
<td class="num">(76)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(76)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares', window );">Repurchases of common stock, Shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(6.5)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue', window );">Repurchases of common stock</a></td>
<td class="num">(1,592)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(1,592)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquityOther', window );">Other</a></td>
<td class="nump">5<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">5<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Ending Balance, Shares at Jun. 30, 2021</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">569.6<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of end of period at Jun. 30, 2021</a></td>
<td class="nump">8,247<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">31,877<span></span>
</td>
<td class="num">(22,762)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(868)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward', window );"><strong>Increase (Decrease) in Stockholders' Equity [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income for basic and diluted EPS</a></td>
<td class="nump">1,884<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1,884<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossNetOfTax', window );">Other comprehensive income (loss), net of taxes</a></td>
<td class="nump">60<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">60<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DividendsCommonStockCash', window );">Dividends declared on common stock</a></td>
<td class="num">(1,017)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(1,017)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation', window );">Issuance of common stock in connection with the Company&#8217;s equity award programs, Shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0.0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation', window );">Issuance of common stock in connection with the Company&#8217;s equity award programs</a></td>
<td class="nump">9<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">9<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue', window );">Stock-based compensation expense</a></td>
<td class="nump">111<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">111<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet', window );">Tax impact related to employee stock-based compensation expense</a></td>
<td class="num">(8)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(8)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares', window );">Repurchases of common stock, Shares</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(4.6)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue', window );">Repurchases of common stock</a></td>
<td class="num">$ (1,069)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(1,069)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockSharesOutstanding', window );">Ending Balance, Shares at Sep. 30, 2021</a></td>
<td class="nump">565.0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">565.0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rc">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of end of period at Sep. 30, 2021</a></td>
<td class="nump">$ 8,217<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 31,989<span></span>
</td>
<td class="num">$ (22,964)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">$ (808)<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of increase (decrease) in additional paid in capital (APIC) resulting from a tax benefit (deficiency) associated with an share-based compensation plan other than an employee stock ownership plan (ESOP).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of increase to additional paid-in capital (APIC) for recognition of cost for award under share-based payment arrangement.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 20<br> -Section 55<br> -Paragraph 12<br> -URI http://asc.fasb.org/extlink&amp;oid=122142933&amp;loc=d3e11149-113907<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=120381028&amp;loc=d3e5047-113901<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 20<br> -Section 55<br> -Paragraph 13<br> -URI http://asc.fasb.org/extlink&amp;oid=122142933&amp;loc=d3e11178-113907<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 10<br> -Section 35<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=123468992&amp;loc=d3e4534-113899<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommonStockSharesOutstanding">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Number of shares of common stock outstanding. Common stock represent the ownership interest in a corporation.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=d3e21463-112644<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommonStockSharesOutstanding</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DividendsCommonStockCash">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of paid and unpaid common stock dividends declared with the form of settlement in cash.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -URI http://asc.fasb.org/extlink&amp;oid=120397183&amp;loc=d3e187085-122770<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DividendsCommonStockCash</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncreaseDecreaseInStockholdersEquityRollForward</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetIncomeLoss">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(22))<br> -URI http://asc.fasb.org/extlink&amp;oid=120399700&amp;loc=SL114874048-224260<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22595-107794<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(18))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123482062&amp;loc=SL123482106-238011<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 50<br> -Paragraph 6<br> -URI http://asc.fasb.org/extlink&amp;oid=124431353&amp;loc=SL124452729-227067<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 8: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(20))<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br><br>Reference 9: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22499-107794<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 9<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22663-107794<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 17: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123596393&amp;loc=d3e14064-108612<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22583-107794<br><br>Reference 20: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 21: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=SL5780133-109256<br><br>Reference 22: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br><br>Reference 23: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22658-107794<br><br>Reference 24: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1A<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669619-108580<br><br>Reference 25: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 31<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8924-108599<br><br>Reference 26: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 27: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 28: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 205<br> -SubTopic 20<br> -Section 50<br> -Paragraph 7<br> -URI http://asc.fasb.org/extlink&amp;oid=109222650&amp;loc=SL51721683-107760<br><br>Reference 29: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1B<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669625-108580<br><br>Reference 30: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 31: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 32: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(B))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 33: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 34: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8906-108599<br><br>Reference 35: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetIncomeLoss</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherComprehensiveIncomeLossNetOfTax">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount after tax and reclassification adjustments of other comprehensive income (loss).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1A<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669619-108580<br><br>Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=124431353&amp;loc=SL124442407-227067<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=d3e21463-112644<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 830<br> -SubTopic 30<br> -Section 45<br> -Paragraph 17<br> -URI http://asc.fasb.org/extlink&amp;oid=118261656&amp;loc=d3e32136-110900<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(21))<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 55<br> -Paragraph 15<br> -URI http://asc.fasb.org/extlink&amp;oid=124507222&amp;loc=d3e1436-108581<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 830<br> -SubTopic 30<br> -Section 45<br> -Paragraph 20<br> -URI http://asc.fasb.org/extlink&amp;oid=118261656&amp;loc=d3e32211-110900<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 830<br> -SubTopic 30<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=6450520&amp;loc=d3e32583-110901<br><br>Reference 9: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 50<br> -Paragraph 5<br> -URI http://asc.fasb.org/extlink&amp;oid=124431353&amp;loc=SL124442411-227067<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1B<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669625-108580<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(23))<br> -URI http://asc.fasb.org/extlink&amp;oid=120399700&amp;loc=SL114874048-224260<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(19))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherComprehensiveIncomeLossNetOfTax</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Number, after forfeiture, of shares or units issued under share-based payment arrangement. Excludes shares or units issued under employee stock ownership plan (ESOP).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=d3e21463-112644<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -URI http://asc.fasb.org/extlink&amp;oid=120397183&amp;loc=d3e187085-122770<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(28))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Value, after forfeiture, of shares issued under share-based payment arrangement. Excludes employee stock ownership plan (ESOP).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -URI http://asc.fasb.org/extlink&amp;oid=120397183&amp;loc=d3e187085-122770<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=120381028&amp;loc=d3e5047-113901<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(28))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 718<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (d)(1)<br> -URI http://asc.fasb.org/extlink&amp;oid=120381028&amp;loc=d3e5070-113901<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Number of shares that have been repurchased and retired during the period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(28))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -URI http://asc.fasb.org/extlink&amp;oid=120397183&amp;loc=d3e187085-122770<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=d3e21463-112644<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockRepurchasedAndRetiredDuringPeriodShares</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Equity impact of the value of stock that has been repurchased and retired during the period. The excess of the purchase price over par value can be charged against retained earnings (once the excess is fully allocated to additional paid in capital).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(28))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=d3e21463-112644<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -URI http://asc.fasb.org/extlink&amp;oid=120397183&amp;loc=d3e187085-122770<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockRepurchasedAndRetiredDuringPeriodValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockholdersEquity">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Total of all stockholders' equity (deficit) items, net of receivables from officers, directors, owners, and affiliates of the entity which are attributable to the parent. The amount of the economic entity's stockholders' equity attributable to the parent excludes the amount of stockholders' equity which is allocable to that ownership interest in subsidiary equity which is not attributable to the parent (noncontrolling interest, minority interest). This excludes temporary equity and is sometimes called permanent equity.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 310<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SAB Topic 4.E)<br> -URI http://asc.fasb.org/extlink&amp;oid=122038336&amp;loc=d3e74512-122707<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(31))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(30))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 7: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123596393&amp;loc=d3e14064-108612<br><br>Reference 8: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockholdersEquity</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockholdersEquityOther">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>This element represents movements included in the statement of changes in stockholders' equity which are not separately disclosed or provided for elsewhere in the taxonomy.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockholdersEquityOther</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>17
<FILENAME>R7.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304056133496">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Condensed Consolidated Statements of Stockholders' Equity (Parenthetical) - $ / shares<br></strong></div></th>
<th class="th" colspan="3">1 Months Ended</th>
<th class="th" colspan="4">3 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Jul. 31, 2021</div></th>
<th class="th"><div>Mar. 31, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Mar. 31, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Mar. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StatementOfStockholdersEquityAbstract', window );"><strong>Statement of Stockholders' Equity [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockDividendsPerShareDeclared', window );">Common stock, dividends declared per share (in usd per share)</a></td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="nump">$ 1.60<span></span>
</td>
<td class="nump">$ 1.60<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommonStockDividendsPerShareDeclared">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Aggregate dividends declared during the period for each share of common stock outstanding.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -URI http://asc.fasb.org/extlink&amp;oid=120397183&amp;loc=d3e187085-122770<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommonStockDividendsPerShareDeclared</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementOfStockholdersEquityAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementOfStockholdersEquityAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>18
<FILENAME>R8.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051477704">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Condensed Consolidated Statements of Cash Flows - USD ($)<br> $ in Millions</strong></div></th>
<th class="th" colspan="2">9 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract', window );"><strong>Cash flows from operating activities:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income</a></td>
<td class="nump">$ 3,994<span></span>
</td>
<td class="nump">$ 5,649<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DepreciationDepletionAndAmortization', window );">Depreciation, amortization and other</a></td>
<td class="nump">2,546<span></span>
</td>
<td class="nump">2,728<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DeferredIncomeTaxesAndTaxCredits', window );">Deferred income taxes</a></td>
<td class="num">(264)<span></span>
</td>
<td class="num">(339)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff', window );">Acquired in-process research and development</a></td>
<td class="nump">1,505<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherNoncashIncomeExpense', window );">Other items, net</a></td>
<td class="nump">187<span></span>
</td>
<td class="nump">270<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract', window );"><strong>Changes in operating assets and liabilities, net of acquisitions:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInAccountsReceivable', window );">Trade receivables, net</a></td>
<td class="num">(269)<span></span>
</td>
<td class="num">(31)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInInventories', window );">Inventories</a></td>
<td class="num">(215)<span></span>
</td>
<td class="num">(316)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInOtherOperatingAssets', window );">Other assets</a></td>
<td class="num">(373)<span></span>
</td>
<td class="nump">64<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInAccountsPayable', window );">Accounts payable</a></td>
<td class="num">(260)<span></span>
</td>
<td class="num">(202)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable', window );">Accrued income taxes, net</a></td>
<td class="num">(719)<span></span>
</td>
<td class="num">(301)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_IncreaseDecreaseInNoncurrentTaxLiability', window );">Long-term tax liabilities</a></td>
<td class="nump">102<span></span>
</td>
<td class="nump">110<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities', window );">Other liabilities</a></td>
<td class="nump">219<span></span>
</td>
<td class="nump">712<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetCashProvidedByUsedInOperatingActivities', window );">Net cash provided by operating activities</a></td>
<td class="nump">6,453<span></span>
</td>
<td class="nump">8,344<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract', window );"><strong>Cash flows from investing activities:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired', window );">Payments to Acquire Businesses, Net of Cash Acquired</a></td>
<td class="num">(1,639)<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_PaymentsToAcquireMarketableSecurities', window );">Purchases of marketable securities</a></td>
<td class="num">(8,901)<span></span>
</td>
<td class="num">(5,329)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt', window );">Proceeds from sales of marketable securities</a></td>
<td class="nump">4,403<span></span>
</td>
<td class="nump">2,597<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities', window );">Proceeds from maturities of marketable securities</a></td>
<td class="nump">7,927<span></span>
</td>
<td class="nump">2,338<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment', window );">Purchases of property, plant and equipment</a></td>
<td class="num">(593)<span></span>
</td>
<td class="num">(435)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_PaymentsToAcquireEquityMethodInvestments', window );">Purchases of equity method investments</a></td>
<td class="num">(154)<span></span>
</td>
<td class="num">(3,154)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_PaymentsForProceedsFromOtherInvestingActivities', window );">Other</a></td>
<td class="num">(80)<span></span>
</td>
<td class="num">(34)<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetCashProvidedByUsedInInvestingActivities', window );">Net cash provided by (used in) investing activities</a></td>
<td class="nump">963<span></span>
</td>
<td class="num">(4,017)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract', window );"><strong>Cash flows from financing activities:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ProceedsFromIssuanceOfLongTermDebt', window );">Net proceeds from issuance of debt</a></td>
<td class="nump">4,946<span></span>
</td>
<td class="nump">8,914<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RepaymentsOfLongTermDebt', window );">Repayment of debt</a></td>
<td class="nump">0<span></span>
</td>
<td class="num">(5,000)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_PaymentsForRepurchaseOfCommonStock', window );">Repurchases of common stock</a></td>
<td class="num">(3,532)<span></span>
</td>
<td class="num">(2,281)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_PaymentsOfDividendsCommonStock', window );">Dividends paid</a></td>
<td class="num">(3,023)<span></span>
</td>
<td class="num">(2,823)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities', window );">Other</a></td>
<td class="num">(104)<span></span>
</td>
<td class="num">(87)<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetCashProvidedByUsedInFinancingActivities', window );">Net cash used in financing activities</a></td>
<td class="num">(1,713)<span></span>
</td>
<td class="num">(1,277)<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect', window );">Increase in cash and cash equivalents</a></td>
<td class="nump">5,703<span></span>
</td>
<td class="nump">3,050<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents', window );">Cash and cash equivalents at beginning of period</a></td>
<td class="nump">6,266<span></span>
</td>
<td class="nump">6,037<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents', window );">Cash and cash equivalents at end of period</a></td>
<td class="nump">$ 11,969<span></span>
</td>
<td class="nump">$ 9,087<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_IncreaseDecreaseInNoncurrentTaxLiability">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Increase (Decrease) In Noncurrent Tax Liability</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_IncreaseDecreaseInNoncurrentTaxLiability</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of cash and cash equivalents, and cash and cash equivalents restricted to withdrawal or usage. Excludes amount for disposal group and discontinued operations. Cash includes, but is not limited to, currency on hand, demand deposits with banks or financial institutions, and other accounts with general characteristics of demand deposits. Cash equivalents include, but are not limited to, short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 24<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3521-108585<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3044-108585<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -URI http://asc.fasb.org/extlink&amp;oid=123431023&amp;loc=SL98516268-108586<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of increase (decrease) in cash, cash equivalents, and cash and cash equivalents restricted to withdrawal or usage; including effect from exchange rate change. Cash includes, but is not limited to, currency on hand, demand deposits with banks or financial institutions, and other accounts with general characteristics of demand deposits. Cash equivalents include, but are not limited to, short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 830<br> -SubTopic 230<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=123444420&amp;loc=d3e33268-110906<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 24<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3521-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DeferredIncomeTaxesAndTaxCredits">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of deferred income tax expense (benefit) and income tax credits.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DeferredIncomeTaxesAndTaxCredits</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DepreciationDepletionAndAmortization">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The aggregate expense recognized in the current period that allocates the cost of tangible assets, intangible assets, or depleting assets to periods that benefit from use of the assets.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -Subparagraph (e)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DepreciationDepletionAndAmortization</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncreaseDecreaseInAccountsPayable">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The increase (decrease) during the reporting period in the aggregate amount of liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncreaseDecreaseInAccountsPayable</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncreaseDecreaseInAccountsReceivable">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The increase (decrease) during the reporting period in amount due within one year (or one business cycle) from customers for the credit sale of goods and services.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncreaseDecreaseInAccountsReceivable</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The increase (decrease) during the period in the amount due for taxes based on the reporting entity's earnings or attributable to the entity's income earning process (business presence) within a given jurisdiction.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncreaseDecreaseInInventories">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The increase (decrease) during the reporting period in the aggregate value of all inventory held by the reporting entity, associated with underlying transactions that are classified as operating activities.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncreaseDecreaseInInventories</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncreaseDecreaseInOperatingCapitalAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncreaseDecreaseInOtherOperatingAssets">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of increase (decrease) in operating assets classified as other.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncreaseDecreaseInOtherOperatingAssets</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of increase (decrease) in operating liabilities classified as other.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncreaseDecreaseInOtherOperatingLiabilities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetCashProvidedByUsedInFinancingActivities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of cash inflow (outflow) from financing activities, including discontinued operations. Financing activity cash flows include obtaining resources from owners and providing them with a return on, and a return of, their investment; borrowing money and repaying amounts borrowed, or settling the obligation; and obtaining and paying for other resources obtained from creditors on long-term credit.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 24<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3521-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetCashProvidedByUsedInFinancingActivities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetCashProvidedByUsedInInvestingActivities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of cash inflow (outflow) from investing activities, including discontinued operations. Investing activity cash flows include making and collecting loans and acquiring and disposing of debt or equity instruments and property, plant, and equipment and other productive assets.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 24<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3521-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetCashProvidedByUsedInInvestingActivities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetCashProvidedByUsedInOperatingActivities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of cash inflow (outflow) from operating activities, including discontinued operations. Operating activity cash flows include transactions, adjustments, and changes in value not defined as investing or financing activities.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 25<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3536-108585<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 24<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3521-108585<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetCashProvidedByUsedInOperatingActivities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetIncomeLoss">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(22))<br> -URI http://asc.fasb.org/extlink&amp;oid=120399700&amp;loc=SL114874048-224260<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22595-107794<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(18))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123482062&amp;loc=SL123482106-238011<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 50<br> -Paragraph 6<br> -URI http://asc.fasb.org/extlink&amp;oid=124431353&amp;loc=SL124452729-227067<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 8: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(20))<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br><br>Reference 9: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22499-107794<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 9<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22663-107794<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 17: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123596393&amp;loc=d3e14064-108612<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22583-107794<br><br>Reference 20: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 21: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=SL5780133-109256<br><br>Reference 22: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br><br>Reference 23: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22658-107794<br><br>Reference 24: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1A<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669619-108580<br><br>Reference 25: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 31<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8924-108599<br><br>Reference 26: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 27: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 28: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 205<br> -SubTopic 20<br> -Section 50<br> -Paragraph 7<br> -URI http://asc.fasb.org/extlink&amp;oid=109222650&amp;loc=SL51721683-107760<br><br>Reference 29: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1B<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669625-108580<br><br>Reference 30: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 31: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 32: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(B))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 33: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 34: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8906-108599<br><br>Reference 35: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetIncomeLoss</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherNoncashIncomeExpense">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of income (expense) included in net income that results in no cash inflow (outflow), classified as other.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherNoncashIncomeExpense</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PaymentsForProceedsFromOtherInvestingActivities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of cash (inflow) outflow from investing activities classified as other.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 13<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3213-108585<br><br>Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 12<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3179-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PaymentsForProceedsFromOtherInvestingActivities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PaymentsForRepurchaseOfCommonStock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The cash outflow to reacquire common stock during the period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 15<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3291-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PaymentsForRepurchaseOfCommonStock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PaymentsOfDividendsCommonStock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of cash outflow in the form of ordinary dividends to common shareholders of the parent entity.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 15<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3291-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PaymentsOfDividendsCommonStock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The cash outflow associated with the acquisition of a business, net of the cash acquired from the purchase.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 13<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3213-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PaymentsToAcquireEquityMethodInvestments">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The cash outflow associated with the purchase of or advances to an equity method investments, which are investments in joint ventures and entities in which the entity has an equity ownership interest normally of 20 to 50 percent and exercises significant influence.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 13<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3213-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PaymentsToAcquireEquityMethodInvestments</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PaymentsToAcquireMarketableSecurities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of cash outflow for purchase of marketable security.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 45<br> -Paragraph 11<br> -URI http://asc.fasb.org/extlink&amp;oid=124260329&amp;loc=d3e26853-111562<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PaymentsToAcquireMarketableSecurities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The cash outflow associated with the acquisition of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale; includes cash outflows to pay for construction of self-constructed assets.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 13<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3213-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PaymentsToAcquirePropertyPlantAndEquipment</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ProceedsFromIssuanceOfLongTermDebt">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The cash inflow from a debt initially having maturity due after one year or beyond the operating cycle, if longer.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 14<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3255-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ProceedsFromIssuanceOfLongTermDebt</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of cash inflow from maturity, prepayment and call of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 45<br> -Paragraph 11<br> -URI http://asc.fasb.org/extlink&amp;oid=124260329&amp;loc=d3e26853-111562<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 11<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3151-108585<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 12<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3179-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of cash inflow (outflow) from financing activities classified as other.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 14<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3255-108585<br><br>Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 15<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3291-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ProceedsFromPaymentsForOtherFinancingActivities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of cash inflow from sale of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 45<br> -Paragraph 11<br> -URI http://asc.fasb.org/extlink&amp;oid=124260329&amp;loc=d3e26853-111562<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 11<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3151-108585<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 12<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3179-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_RepaymentsOfLongTermDebt">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The cash outflow for debt initially having maturity due after one year or beyond the normal operating cycle, if longer.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 15<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3291-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_RepaymentsOfLongTermDebt</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The amount of the write-off for research and development assets that were acquired in a transaction other than a business combination.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16265-109275<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>19
<FILENAME>R9.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304045777080">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Summary of significant accounting policies<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AccountingPoliciesAbstract', window );"><strong>Accounting Policies [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_SignificantAccountingPoliciesTextBlock', window );">Summary of significant accounting policies</a></td>
<td class="text">Summary of significant accounting policies<div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Business</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Amgen Inc. (including its subsidiaries, referred to as &#8220;Amgen,&#8221; &#8220;the Company,&#8221; &#8220;we,&#8221; &#8220;our&#8221; or &#8220;us&#8221;) is a global biotechnology pioneer that discovers, develops, manufactures and delivers innovative human therapeutics.&#160;We operate in one business segment: human therapeutics.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Basis of presentation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The financial information for the three and nine months ended September 30, 2021 and 2020, is unaudited but includes all adjustments (consisting of only normal, recurring adjustments unless otherwise indicated), which Amgen considers necessary for a fair presentation of its condensed consolidated results of operations for those periods. Interim results are not necessarily indicative of results for the full fiscal year.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The condensed consolidated financial statements should be read in conjunction with our consolidated financial statements and the notes thereto contained in our Annual Report on Form 10-K for the year ended December 31, 2020, and with our condensed consolidated financial statements and the notes thereto contained in our Quarterly Reports on Form 10-Q for the periods ended March 31, 2021 and June 30, 2021.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Principles of consolidation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The condensed consolidated financial statements include the accounts of Amgen as well as its majority-owned subsidiaries. We do not have any significant interests in any</span><span style="color:#ff0000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">variable interest entities. All material intercompany transactions and balances have been eliminated in consolidation.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Use of estimates</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The preparation of condensed consolidated financial statements in conformity with U.S. generally accepted accounting principles (GAAP) requires management to make estimates and assumptions that affect the amounts reported in the condensed consolidated financial statements and accompanying notes. Actual results may differ from those estimates.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Property, plant and equipment, net</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Property, plant and equipment is recorded at historical cost, net of accumulated depreciation and amortization of $9.2&#160;billion and $9.0 billion as of September 30, 2021 and December 31, 2020, respectively.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Recent accounting pronouncements</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In March 2020, the Financial Accounting Standards Board (FASB) issued a new accounting standard to ease the financial reporting burdens caused by the expected market transition from the London Interbank Offered Rate (LIBOR) and other interbank offered rates to alternative reference rates, commonly referred to as reference rate reform. The new standard provides temporary optional expedients and exceptions to current GAAP guidance on contract modifications and hedge accounting. Specifically, a modification to transition to an alternative reference rate is treated as an event that does not require contract remeasurement or reassessment of a previous accounting treatment. Moreover, for all types of hedging relationships, an entity is permitted to change the reference rate without having to dedesignate the hedging relationship. The standard is generally effective for all contract modifications made and hedging relationships evaluated through December 31, 2022. In January 2021, the FASB issued a new accounting standard to expand on the scope of the original March 2020 standard to include derivative instruments on discounting transactions. We are currently evaluating the impacts that the two standards will have on our condensed consolidated financial statements.</span></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccountingPoliciesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccountingPoliciesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SignificantAccountingPoliciesTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for all significant accounting policies of the reporting entity.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=123372394&amp;loc=d3e18726-107790<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -URI http://asc.fasb.org/topic&amp;trid=2122369<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SignificantAccountingPoliciesTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>20
<FILENAME>R10.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304045874312">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Business Combinations and Asset Acquisitions<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_BusinessCombinationAndAssetAcquisitionAbstract', window );"><strong>Business Combination and Asset Acquisition [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_BusinessCombinationDisclosureTextBlock', window );">Business Combination Disclosure [Text Block]</a></td>
<td class="text">Acquisitions<div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On April 16, 2021, Amgen completed its acquisition of Five Prime Therapeutics, Inc. (Five Prime) for total consideration of $1.6&#160;billion, net of cash acquired. The purchase price was funded with cash on hand. This transaction was accounted for as an asset acquisition because substantially all the value of the assets acquired was concentrated in the intellectual property rights of bemarituzumab, a phase 3 trial-ready, first-in-class program for gastric cancer. Five Prime&#8217;s operations have been included in our condensed consolidated financial statements commencing after the acquisition date.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We allocated the consideration to acquire Five Prime to: the bemarituzumab in-process research and development (IPR&amp;D) program of $1.5&#160;billion, which was expensed immediately in Acquired IPR&amp;D expense in the Condensed Consolidated Statements of Income; deferred tax assets of $177&#160;million; and other net liabilities of $47&#160;million. The acquired IPR&amp;D expense was not tax deductible.</span></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_BusinessCombinationAndAssetAcquisitionAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_BusinessCombinationAndAssetAcquisitionAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_BusinessCombinationDisclosureTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for a business combination (or series of individually immaterial business combinations) completed during the period, including background, timing, and recognized assets and liabilities. The disclosure may include leverage buyout transactions (as applicable).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 805<br> -URI http://asc.fasb.org/topic&amp;trid=2303972<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_BusinessCombinationDisclosureTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>21
<FILENAME>R11.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304047180856">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Revenues<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerAbstract', window );"><strong>Revenue from Contract with Customer [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerTextBlock', window );">Revenues</a></td>
<td class="text">Revenues<div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We operate in one business segment: human therapeutics. Therefore, results of our operations are reported on a consolidated basis for purposes of segment reporting, consistent with internal management reporting. Revenues by product and by geographic area, based on customers&#8217; locations, are presented below. The majority of rest-of-world (ROW) revenues relates to products sold in Europe.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Revenues were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:32.818%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.133%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.133%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.823%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.133%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.133%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.133%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.144%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="33" style="border-bottom:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended September 30,</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S.</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">ROW</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S.</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">ROW</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Enbrel</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(etanercept)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,263&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">26&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,289&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,289&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">36&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,325&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (denosumab)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">530&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">273&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">803&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">478&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">223&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">701&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(apremilast)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">495&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">114&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">609&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">439&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">99&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">538&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (denosumab)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">372&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">145&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">517&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">363&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">118&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">481&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(pegfilgrastim)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">360&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">55&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">415&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">484&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">71&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">555&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(darbepoetin alfa)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">149&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">247&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">396&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">158&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">226&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">384&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(evolocumab)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">139&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">133&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">272&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">92&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">113&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">205&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(carfilzomib)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">198&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">95&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">293&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">173&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">87&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">260&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other products</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,052&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">674&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,726&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,142&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">513&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,655&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total product sales</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,558&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,762&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,320&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,618&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,486&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,104&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other revenues</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">386&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">319&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total revenues</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,706&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,423&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:15pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="33" style="border-bottom:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended September 30,</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S.</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">ROW</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S.</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">ROW</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">ENBREL</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,270&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">87&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,357&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,619&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">105&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,724&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,569&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">806&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,375&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,341&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">673&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,014&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,284&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">335&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,619&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,280&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">298&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,578&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> </span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,061&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">412&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,473&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,036&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">361&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,397&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,215&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">168&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,383&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,538&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">219&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,757&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">409&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">709&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,118&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">489&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">704&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,193&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">421&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">423&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">844&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">331&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">303&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">634&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">547&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">277&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">824&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">527&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">266&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">793&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other products</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,059&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,974&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5,033&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,164&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,652&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,816&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total product sales</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,835&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5,191&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18,026&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13,325&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,581&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">17,906&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other revenues</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,107&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">884&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total revenues</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">19,133&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18,790&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:15pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:3pt double #000000;padding:0 1pt"/></tr></table></div><div style="margin-top:4pt;padding-left:13.5pt;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">____________</span></div>(1)&#160;&#160;&#160;&#160;Hedging gains and losses, which are included in product sales, were not material for the three and nine months ended September 30, 2021 and 2020.<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_RevenueFromContractWithCustomerAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_RevenueFromContractWithCustomerAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_RevenueFromContractWithCustomerTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure of revenue from contract with customer to transfer good or service and to transfer nonfinancial asset. Includes, but is not limited to, disaggregation of revenue, credit loss recognized from contract with customer, judgment and change in judgment related to contract with customer, and asset recognized from cost incurred to obtain or fulfill contract with customer. Excludes insurance and lease contracts.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -URI http://asc.fasb.org/topic&amp;trid=49130388<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130551-203045<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 13<br> -Subparagraph (b)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130556-203045<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 12<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130554-203045<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 9<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130550-203045<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 12<br> -Subparagraph (e)<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130554-203045<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 12<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130554-203045<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 12<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130554-203045<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 15<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130558-203045<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 12<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130554-203045<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_RevenueFromContractWithCustomerTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>22
<FILENAME>R12.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304047120952">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Income taxes<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncomeTaxDisclosureAbstract', window );"><strong>Income Tax Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncomeTaxDisclosureTextBlock', window );">Income taxes</a></td>
<td class="text">Income taxes<div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The effective tax rate for the three and nine months ended September 30, 2021, was 12.6% for both periods, compared with rates of 8.4% and 9.7%, respectively, for the corresponding periods of the prior year.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The increase in our effective tax rate for the three and nine months ended September 30, 2021, was primarily due to the non-deductible IPR&amp;D expense arising from the acquisition of Five Prime and prior year favorable items partially offset by a change in earnings mix. The effective tax rates differ from the federal statutory rate primarily as a result of foreign earnings from the Company&#8217;s operations conducted in Puerto Rico, a territory of the United States treated as a foreign jurisdiction for U.S. tax purposes, that are subject to a tax incentive grant through 2035. In addition, the Company&#8217;s operations conducted in Singapore are subject to a tax incentive grant through 2034. These foreign earnings are also subject to U.S. tax at a reduced rate of 10.5%.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The U.S. territory of Puerto Rico imposes an excise tax on the gross intercompany purchase price of goods and services from our manufacturer in Puerto Rico. The rate of 4% is effective through December 31, 2027. We account for the excise tax as a manufacturing cost that is capitalized in inventory and expensed in cost of sales when the related products are sold. For U.S. income tax purposes, the excise tax results in foreign tax credits that are generally recognized in our provision for income taxes when the excise tax is incurred.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">One or more of our legal entities file income tax returns in the U.S. federal jurisdiction, various U.S. state jurisdictions and certain foreign jurisdictions. Our income tax returns are routinely examined by tax authorities in those jurisdictions. Significant disputes may arise with tax authorities involving issues regarding the timing and amount of deductions, the use of tax credits and allocations of income and expenses among various tax jurisdictions because of differing interpretations of tax laws, regulations and relevant facts. In 2017, we received a Revenue Agent Report (RAR) and a modified RAR from the Internal Revenue Service (IRS) for the years 2010, 2011 and 2012 proposing significant adjustments that primarily relate to the allocation of profits between certain of our entities in the United States and the U.S. territory of Puerto Rico. We disagreed with the proposed adjustments and calculations and pursued a resolution with the IRS administrative appeals office. As previously reported, we were unable to reach resolution with the IRS appeals office. In July 2021, we filed a petition in the U.S. Tax Court to contest two duplicate Statutory Notices of Deficiency (Notices) for 2010, 2011 and 2012 that we received in May and July 2021. The duplicate Notices seek to increase our U.S. taxable income by an amount that would result in additional federal tax of approximately $3.6&#160;billion, plus interest. Any additional tax that could be imposed would be reduced by up to approximately $900&#160;million of repatriation tax previously accrued on our foreign earnings. In any event, we firmly believe that the IRS&#8217;s positions in the Notices are without merit, and we will vigorously contest the Notices through the judicial process.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:112%">In addition, in 2020, we received an RAR and a modified RAR from the IRS for the years 2013, 2014 and 2015 also proposing significant adjustments that primarily relate to the allocation of profits between certain of our entities in the United States and the U.S. territory of Puerto Rico, similar to those proposed for the years 2010, 2011 and 2012. We disagree with the proposed adjustments and calculations and have been pursuing resolution with the IRS administrative appeals office. As a consequence of the Tax Court litigation for the 2010-2012 period, the IRS administrative appeals office recently informed us that it does not plan to engage in discussions at this time regarding the allocation of profits between our entities in the United States and the U.S. territory of Puerto Rico for the 2013-2015 period. We are currently under examination by the IRS for the years 2016, 2017 and 2018. We are also currently under examination by a number of other state and foreign tax jurisdictions.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:112%">Final resolution of these complex matters is not likely within the next 12 months. We believe our accrual for income tax liabilities is appropriate based on past experience, interpretations of tax law, application of the tax law to our facts and judgments about potential actions by tax authorities; however, due to the complexity of the provision for income taxes and uncertain resolution of these matters, the ultimate outcome of any tax matters may result in payments substantially greater than amounts accrued and could have a material adverse impact on our condensed consolidated financial statements. We are no longer subject to U.S. federal income tax examinations for the years ended on or before December 31, 2009.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">During the three and nine months ended September 30, 2021, the gross amounts of our unrecognized tax benefits (UTBs) increased $70 million and $180&#160;million, respectively, as a result of tax positions taken during the current year. Substantially all of the UTBs as of September 30, 2021, if recognized, would affect our effective tax rate.</span></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxDisclosureTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for income taxes. Disclosures may include net deferred tax liability or asset recognized in an enterprise's statement of financial position, net change during the year in the total valuation allowance, approximate tax effect of each type of temporary difference and carryforward that gives rise to a significant portion of deferred tax liabilities and deferred tax assets, utilization of a tax carryback, and tax uncertainties information.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section 50<br> -Paragraph 21<br> -URI http://asc.fasb.org/extlink&amp;oid=121826272&amp;loc=d3e32857-109319<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SAB Topic 11.C)<br> -URI http://asc.fasb.org/extlink&amp;oid=122134291&amp;loc=d3e330215-122817<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section 50<br> -Paragraph 17<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=121826272&amp;loc=d3e32809-109319<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB TOPIC 6.I.5.Q1)<br> -URI http://asc.fasb.org/extlink&amp;oid=122134291&amp;loc=d3e330036-122817<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section 50<br> -Paragraph 14<br> -URI http://asc.fasb.org/extlink&amp;oid=121826272&amp;loc=d3e32705-109319<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 270<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=6424409&amp;loc=d3e44925-109338<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -URI http://asc.fasb.org/topic&amp;trid=2144680<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 30<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=6424122&amp;loc=d3e41874-109331<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(h)(2))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxDisclosureTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>23
<FILENAME>R13.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051840616">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Earnings per share<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EarningsPerShareAbstract', window );"><strong>Earnings Per Share [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EarningsPerShareTextBlock', window );">Earnings per share</a></td>
<td class="text">Earnings per share<div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The computation of basic earnings per share (EPS) is based on the weighted-average number of our common shares outstanding. The computation of diluted EPS is based on the weighted-average number of our common shares outstanding and dilutive potential common shares, which primarily include shares that may be issued under our stock option, restricted stock and performance unit award programs (collectively, dilutive securities), as determined by using the treasury stock method.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The computations for basic and diluted EPS were as follows (in millions, except per-share data):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:45.829%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.619%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.619%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.619%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.624%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:120%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income (Numerator):</span></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income for basic and diluted EPS</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,884&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,021&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,994&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5,649&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Shares (Denominator):</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Weighted-average shares for basic EPS</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">567&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">585&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">572&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">588&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Effect of dilutive securities</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Weighted-average shares for diluted EPS</span></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">570&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">589&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">576&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">592&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:15pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Basic EPS</span></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.32&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.45&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.98&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9.61&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Diluted EPS</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.31&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.43&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.93&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9.54&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">For the three and nine months ended September 30, 2021 and 2020, the number of antidilutive employee stock-based awards excluded from the computation of diluted EPS was not significant.</span></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EarningsPerShareAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EarningsPerShareAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EarningsPerShareTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for earnings per share.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=109243012&amp;loc=SL65017193-207537<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=124432515&amp;loc=d3e3550-109257<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -URI http://asc.fasb.org/topic&amp;trid=2144383<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=124432515&amp;loc=d3e3630-109257<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EarningsPerShareTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>24
<FILENAME>R14.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304045692312">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Collaborations<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract', window );"><strong>Organization, Consolidation and Presentation of Financial Statements [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CollaborativeArrangementDisclosureTextBlock', window );">Collaborations</a></td>
<td class="text">Collaborations<div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On July 30, 2021, we closed our collaboration and licensing agreement with Kyowa Kirin Co., Ltd. (KKC) to jointly develop and commercialize an anti-OX40 fully human monoclonal antibody (AMG 451) worldwide, except in Japan. AMG 451 is for the treatment of atopic dermatitis, with potential in other autoimmune diseases.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Under the terms of the agreement, we will lead the global development, manufacturing and commercialization of AMG 451, except in Japan. KKC will co-promote AMG 451 with Amgen in the United States and have opt-in rights to co-promote AMG 451 in various other markets outside the United States, including in Europe and Asia. </span></div>We made an upfront payment of $400&#160;million to KKC that was recognized in Research and development (R&amp;D) expense in the third quarter of 2021. Amgen and KKC will share equally the global development costs, except in Japan, and the U.S. commercialization costs. Outside of the United States and Japan, any commercialization costs incurred by KKC will be reimbursed by Amgen. We may also be required to make milestone payments of up to $850&#160;million contingent upon the achievement of certain regulatory events and commercial thresholds. We will also pay KKC significant double-digit royalties on global sales, except in Japan.<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CollaborativeArrangementDisclosureTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for collaborative arrangements in which the entity is a participant, including a) information about the nature and purpose of such arrangements; b) its rights and obligations thereunder; c) the accounting policy for collaborative arrangements; and d) the income statement classification and amounts attributable to transactions arising from the collaborative arrangement between participants.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 808<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=6931272&amp;loc=SL5834143-161434<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 808<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=6931272&amp;loc=SL5834143-161434<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 808<br> -URI http://asc.fasb.org/topic&amp;trid=5833765<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CollaborativeArrangementDisclosureTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>25
<FILENAME>R15.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304045783832">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Investments<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract', window );"><strong>Investments, Debt and Equity Securities [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock', window );">Investments</a></td>
<td class="text">Investments<div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Available-for-sale investments</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The amortized cost, gross unrealized gains, gross unrealized losses and fair values of interest-bearing securities, which are considered available-for-sale, by type of security were as follows (in millions):</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:42.174%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.350%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.350%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.350%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.356%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Types of securities as of September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Amortized<br/>cost</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>unrealized<br/>gains</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>unrealized<br/>losses</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair<br/>values</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">51&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">51&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury bills</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,900&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,900&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Money market mutual funds</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">8,323&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">8,323&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other short-term interest-bearing securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total interest-bearing securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,275&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,275&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span><br/></span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:42.174%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.350%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.350%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.350%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.356%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Types of securities as of December 31, 2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Amortized<br/>cost</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>unrealized<br/>gains</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>unrealized<br/>losses</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair<br/>values</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">129&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">130&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury bills</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,948&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,948&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Money market mutual funds</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,765&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,765&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other short-term interest-bearing securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total interest-bearing securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9,844&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9,845&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of interest-bearing securities by location in the Condensed Consolidated Balance Sheets were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:64.397%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.423%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated Balance Sheets locations</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash and cash equivalents</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">11,323&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5,464&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Marketable securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">952&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,381&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total interest-bearing securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,275&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9,845&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Cash and cash equivalents in the above table excludes bank account cash of $646 million and $802&#160;million as of September 30, 2021 and December 31, 2020, respectively.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of available-for-sale investments by contractual maturity were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:64.397%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.423%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Contractual maturities</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Maturing in one year or less</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,275&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9,795&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Maturing after one year through three years</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">50&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total available-for-sale investments </span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,275&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9,845&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">For the three and nine months ended September 30, 2021 and 2020, realized gains and losses on interest-bearing securities were not material. Realized gains and losses on interest-bearing securities are recorded in Other income, net, in the Condensed Consolidated Statements of Income. The cost of securities sold is based on the specific-identification method.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The primary objective of our investment portfolio is to maintain safety of principal, prudent levels of liquidity and acceptable levels of risk. Our investment policy limits interest-bearing security investments to certain types of debt and money market instruments issued by institutions with investment-grade credit ratings, and it places restrictions on maturities and concentration by asset class and issuer. </span></div><div style="margin-bottom:8pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Equity securities</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We held investments in equity securities with readily determinable fair values (publicly traded securities) of $608 million and $477 million as of September 30, 2021 and December 31, 2020, respectively, which are included in Other noncurrent assets in the Condensed Consolidated Balance Sheets. For the three months ended September 30, 2021 and 2020, net unrealized gains on publicly traded securities were $135&#160;million and $60&#160;million, respectively. For the nine months ended September 30, 2021 and 2020, net unrealized gains on publicly traded securities were $104&#160;million and $65&#160;million, respectively. Realized gains and losses on sales of publicly traded securities for the three and nine months ended September 30, 2021 and 2020 were not material.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We held investments of $255 million and $203 million in equity securities without readily determinable fair values as of September 30, 2021 and December 31, 2020, respectively, which are included in Other noncurrent assets in the Condensed Consolidated Balance Sheets. For the three months ended September 30, 2021 and 2020, gains due to upward adjustments on these securities were $94&#160;million and $12&#160;million, respectively. For the nine months ended September 30, 2021 and 2020, gains due to upward adjustments on these securities were $129&#160;million and $20&#160;million, respectively. Downward adjustments on these securities were not material. Adjustments were based on observable price transactions.</span></div><div style="margin-bottom:8pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Equity method investments </span></div><div style="margin-bottom:8pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">BeiGene, Ltd.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">As of September 30, 2021, we had an ownership interest of approximately 20.3% in BeiGene, Ltd. (BeiGene), which is included in Other noncurrent assets in the Condensed Consolidated Balance Sheets and accounted for under the equity method of accounting. We amortize the difference between the fair value of equity securities acquired and our proportionate share of the carrying value of the underlying net assets of BeiGene over the useful lives of the assets that gave rise to this basis difference. This amortization and our share of the results of operations of BeiGene are included in </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Other income, net</span><span style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, in the Condensed Consolidated Statements of Income one quarter in arrears, which began in the second quarter of 2020. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">During the three and nine months ended September 30, 2021, the carrying value of our equity investment was adjusted by our share of BeiGene&#8217;s net loss of $98&#160;million and $181&#160;million, respectively, and amortization of the basis difference of $44&#160;million and $128&#160;million, respectively. During the three and nine months ended September 30, 2021, the carrying value increased by $18&#160;million and $56&#160;million, respectively, from the impact of BeiGene ownership transactions. In addition, during the three and nine months ended September 30, 2021, we increased the carrying value by $50&#160;million as a result of our purchase of additional shares directly from BeiGene. As of September 30, 2021, the carrying value and fair value of our investment in BeiGene totaled $2.7 billion and $6.9 billion, respectively. As of September 30, 2021, we believe the carrying value of our equity investment in BeiGene is fully recoverable.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Neumora Therapeutics, Inc.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> On September 30, 2021, we acquired approximately 25.9% ownership interest in Neumora Therapeutics, Inc. (Neumora), a privately held company, for $257&#160;million, which is included in Other noncurrent assets in the Condensed Consolidated Balance Sheets, in exchange for a $100&#160;million cash payment and $157&#160;million in noncash consideration primarily related to future services. Although our equity investment provides us with the ability to exercise significant influence over Neumora, we have elected the fair value option to account for our equity investment. Under the fair value option, changes in the fair value of the investment are recognized through earnings each reporting period. We believe the fair value option best reflects the economics of the underlying transaction. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Limited partnerships</span></div><div style="text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We held limited partnership investments of $556 million and $496 million as of September 30, 2021 and December 31, 2020, respectively, which are included in Other noncurrent assets in the Condensed Consolidated Balance Sheets. These investments, primarily investment funds of early-stage biotechnology companies, are accounted for by using the equity method of accounting and are measured by using our proportionate share of the net asset values of the underlying investments held by the limited partnerships as a practical expedient. These investments are typically redeemable only through distributions upon liquidation of the underlying assets. As of September 30, 2021, unfunded additional commitments to be made for these investments during the next several years were not material. For the three months ended September 30, 2021 and 2020, net unrealized gains and losses on our limited partnership investments were a net loss of $43&#160;million and a net gain of $63&#160;million, respectively. For the nine months ended September 30, 2021 and 2020, net unrealized gains from our limited partnership investments were $122&#160;million and $73&#160;million, respectively.</span></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for  investments in certain debt and equity securities.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 320<br> -URI http://asc.fasb.org/subtopic&amp;trid=2209399<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 946<br> -SubTopic 320<br> -URI http://asc.fasb.org/subtopic&amp;trid=2324412<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -URI http://asc.fasb.org/topic&amp;trid=2196928<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 940<br> -SubTopic 320<br> -URI http://asc.fasb.org/subtopic&amp;trid=2176304<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher SEC<br> -Name Regulation S-K (SK)<br> -Number 229<br> -Section 1403<br> -Paragraph (b)<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>26
<FILENAME>R16.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304045777080">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Inventories<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InventoryDisclosureAbstract', window );"><strong>Inventory Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InventoryDisclosureTextBlock', window );">Inventories</a></td>
<td class="text">Inventories<div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Inventories consisted of the following (in millions):</span></div><div><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:65.128%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.422%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Raw materials</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">667&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">486&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Work in process</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,313&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,437&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Finished goods</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,172&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">970&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 5.5pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total inventories</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,152&#160;</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,893&#160;</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InventoryDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InventoryDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InventoryDisclosureTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for inventory. Includes, but is not limited to, the basis of stating inventory, the method of determining inventory cost, the classes of inventory, and the nature of the cost elements included in inventory.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 330<br> -URI http://asc.fasb.org/topic&amp;trid=2126998<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InventoryDisclosureTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>27
<FILENAME>R17.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051687672">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Goodwill and other intangible assets<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2020</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract', window );"><strong>Goodwill and Intangible Assets Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock', window );">Goodwill and other intangible assets</a></td>
<td class="text">Goodwill and other intangible assets<div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Goodwill</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The change in the carrying amount of goodwill was as follows (in millions):</span></div><div><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.707%"><tr><td style="width:1.0%"/><td style="width:82.331%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.469%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30, 2021</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Beginning balance</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14,689&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Currency translation adjustment</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(24)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Ending balance</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14,665&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="text-align:justify"><span><br/></span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Other intangible assets</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Other intangible assets consisted of the following (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:32.087%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.426%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.426%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.426%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.426%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.426%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.433%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>carrying<br/>amounts</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Accumulated<br/>amortization</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other intangible<br/>assets, net</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>carrying<br/>amounts</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Accumulated<br/>amortization</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other intangible<br/>assets, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Finite-lived intangible assets:</span></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Developed-product-technology rights</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">25,575&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(12,222)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13,353&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">25,591&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(10,564)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15,027&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Licensing rights</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,766&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(2,931)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">835&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,743&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(2,791)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">952&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Marketing-related rights</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,362&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1,099)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">263&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,367&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1,041)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">326&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Research and development technology rights</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,298&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1,120)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">178&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,317&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1,065)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">252&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total finite-lived intangible assets</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32,001&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(17,372)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14,629&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32,018&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(15,461)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">16,557&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Indefinite-lived intangible assets:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">In-process research and development</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">30&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">30&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">30&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">30&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total other intangible assets</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32,031&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(17,372)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14,659&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32,048&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(15,461)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">16,587&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="text-align:justify;text-indent:22.5pt"><span><br/></span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Developed-product-technology rights consists of rights related to marketed products. Licensing rights primarily consists of contractual rights to receive future milestone, royalty and profit-sharing payments; capitalized payments to third parties for milestones related to regulatory approvals to commercialize products; and upfront payments associated with royalty obligations for marketed products. Marketing-related rights primarily consists of rights related to the sale and distribution of marketed products. R&amp;D technology rights pertains to technologies used in R&amp;D that have alternative future uses.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">IPR&amp;D consists of R&amp;D projects acquired in a business combination that are not complete at the time of acquisition due to remaining technological risks and/or lack of receipt of required regulatory approvals. We review IPR&amp;D projects for impairment annually, whenever events or changes in circumstances indicate that the carrying amounts may not be recoverable and upon the establishment of technological feasibility or regulatory approval.</span></div>During the three months ended September 30, 2021 and 2020, we recognized amortization associated with our finite-lived intangible assets of $642 million and $708 million, respectively. During the nine months ended September 30, 2021 and 2020, we recognized amortization associated with our finite-lived intangible assets of $1.9 billion and $2.1 billion, respectively. Amortization of intangible assets is primarily included in Cost of sales in the Condensed Consolidated Statements of Income. The total estimated amortization for our finite-lived intangible assets for the remaining three months ending December 31, 2021, and the years ending December 31, 2022, 2023, 2024, 2025 and 2026, are $0.6 billion, $2.5 billion, $2.4 billion, $2.4 billion, $2.2 billion and $1.8 billion, respectively.<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for goodwill and intangible assets.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -URI http://asc.fasb.org/topic&amp;trid=2144416<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>28
<FILENAME>R18.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304047155848">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Financing arrangements<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtDisclosureAbstract', window );"><strong>Debt Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtDisclosureTextBlock', window );">Financing arrangements</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our borrowings consisted of the following (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:65.128%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.422%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1.25% &#8364;1,250 million notes due 2022 (1.25% 2022 euro Notes)</span></div></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,448&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,527&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.70% notes due 2022 (2.70% 2022 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">500&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">500&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.65% notes due 2022 (2.65% 2022 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,500&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,500&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.625% notes due 2022 (3.625% 2022 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">750&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">750&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">0.41% CHF700 million bonds due 2023 (0.41% 2023 Swiss franc Bonds)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">751&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">791&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.25% notes due 2023 (2.25% 2023 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">750&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">750&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.625% notes due 2024 (3.625% 2024 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,400&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,400&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1.90% notes due 2025 (1.90% 2025 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">500&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">500&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.125% notes due 2025 (3.125% 2025 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,000&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,000&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.00% &#8364;750 million notes due 2026 (2.00% 2026 euro Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">869&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">916&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.60% notes due 2026 (2.60% 2026 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.50% &#163;475 million notes due 2026 (5.50% 2026 pound sterling Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">640&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">649&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.20% notes due 2027 (2.20% 2027 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,750&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,750&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.20% notes due 2027 (3.20% 2027 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,000&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,000&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1.65% note due 2028 (1.65% 2028 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.00% &#163;700 million notes due 2029 (4.00% 2029 pound sterling Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">943&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">957&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.45% notes due 2030 (2.45% 2030 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.30% notes due 2031 (2.30% 2031 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.00% notes due 2032 (2.00% 2032 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.375% notes due 2037 (6.375% 2037 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">478&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">478&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.90% notes due 2038 (6.90% 2038 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">254&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">254&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.40% notes due 2039 (6.40% 2039 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">333&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">333&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.15% notes due 2040 (3.15% 2040 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,000&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,000&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.75% notes due 2040 (5.75% 2040 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">373&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">373&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.80% note due 2041 (2.80% 2041 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,150&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.95% notes due 2041 (4.95% 2041 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">600&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">600&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.15% notes due 2041 (5.15% 2041 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">729&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">729&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.65% notes due 2042 (5.65% 2042 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">415&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">415&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.375% notes due 2043 (5.375% 2043 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">185&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">185&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.40% notes due 2045 (4.40% 2045 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,250&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,250&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.563% notes due 2048 (4.563% 2048 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,415&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,415&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.375% notes due 2050 (3.375% 2050 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,250&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,250&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.663% notes due 2051 (4.663% 2051 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,541&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,541&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.00% notes due 2052 (3.00% 2052 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,350&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.77% notes due 2053 (2.77% 2053 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">940&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">940&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other notes due 2097</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">100&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">100&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Unamortized bond discounts, premiums and issuance costs, net</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1,221)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1,188)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Fair value adjustments</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">371&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">566&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total carrying value of debt</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">37,579&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32,986&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Less current portion</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(4,288)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(91)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total long-term debt</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33,291&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32,895&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">There are no material differences between the effective interest rates and coupon rates of any of our borrowings, except for the 4.563% 2048 Notes, the 4.663% 2051 Notes and the 2.77% 2053 Notes, which have effective interest rates of 6.3%, 5.6% and 5.2%, respectively.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">During the three months ended September 30, 2021, we issued $5.0&#160;billion of debt consisting of $1.25&#160;billion of the 1.65% 2028 Notes, $1.25&#160;billion of the 2.00% 2032 Notes, $1.15&#160;billion of the 2.80% 2041 Notes and $1.35&#160;billion of the 3.00% 2052 Notes. In the event of a change-in-control triggering event, as defined in the terms of the notes, we may be required to purchase all or a portion of these notes at a price equal to 101% of the principal amount of the notes plus accrued and unpaid interest. In addition, these notes may be redeemed at any time at our option, in whole or in part, at the principal amount of the notes being redeemed plus accrued and unpaid interest and a make-whole amount, which are defined by the terms of the notes. The notes may be redeemed without payment of make-whole amounts if redemption occurs during a specified period of time immediately prior to the maturing of the notes. Such time periods range from two months to six months prior to maturity.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">During the three months ended June 30, 2021, we entered into the following interest rate swap contracts: (i) $1.0&#160;billion notional amount with respect to the 2.45% 2030 Notes, resulting in an effective interest rate of three-month LIBOR plus 1.0% for that portion of the notes, and (ii) $500&#160;million notional amount with respect to the 2.30% 2031 Notes, resulting in an effective interest rate of three-month LIBOR plus 0.8% for that portion of the notes.</span></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtDisclosureTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for information about short-term and long-term debt arrangements, which includes amounts of borrowings under each line of credit, note payable, commercial paper issue, bonds indenture, debenture issue, own-share lending arrangements and any other contractual agreement to repay funds, and about the underlying arrangements, rationale for a classification as long-term, including repayment terms, interest rates, collateral provided, restrictions on use of assets and activities, whether or not in compliance with debt covenants, and other matters important to users of the financial statements, such as the effects of refinancing and noncompliance with debt covenants.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -URI http://asc.fasb.org/topic&amp;trid=2208564<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1B<br> -Subparagraph (h)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495323-112611<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1C<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495334-112611<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1I<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495371-112611<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1I<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495371-112611<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(c))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1B<br> -Subparagraph (g)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495323-112611<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1C<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495334-112611<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1C<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495334-112611<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1E<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495348-112611<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1B<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495323-112611<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1I<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495371-112611<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1B<br> -Subparagraph (i)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495323-112611<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtDisclosureTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>29
<FILENAME>R19.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304045688264">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Stockholders' equity<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquityAbstract', window );"><strong>Equity [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquityNoteDisclosureTextBlock', window );">Stockholders' equity</a></td>
<td class="text">Stockholders&#8217; equity<div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Stock repurchase program</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Activity under our stock repurchase program, on a trade date basis, was as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:42.321%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.496%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.496%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.496%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.501%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Shares</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Dollars&#160;</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Shares</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Dollars</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">First quarter</span></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.7&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">865&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.3&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">933&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Second quarter</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.5&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,592&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.6&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">591&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Third quarter</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.6&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,069&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.0&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">752&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total stock repurchases</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14.8&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,526&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9.9&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,276&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In March 2021, our Board of Directors increased the amount authorized under our stock repurchase program by an additional $3.4&#160;billion. As of September 30, 2021</span><span style="background-color:#ffffff;color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">, $2.9 billion of aut</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">horization remained available under our stock repurchase program. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In October 2021, the Board of Directors increased the amount authorized under our stock repurchase program by an additional $4.5 billion.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Dividends</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In July 2021, March 2021 and December 2020, the Board of Directors declared a quarterly cash dividend of $1.76 per share, which were paid in September 2021, June 2021 and March 2021, respectively. In October 2021, the Board of Directors declared a quarterly cash dividend of $1.76 per share, which will be paid on December 8, 2021.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Accumulated other comprehensive income (loss)</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The components of Accumulated other comprehensive income (loss) (AOCI) were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:45.537%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.987%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.987%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.987%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.987%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.995%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Foreign<br/>currency<br/>translation</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Cash&#160;flow<br/>hedges</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Available-for-sale<br/>securities</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">AOCI</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of December 31, 2020</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(709)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(263)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(14)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(985)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency translation adjustments</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(39)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(39)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Unrealized gains</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">108&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">108&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Reclassification adjustments to income</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">133&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">133&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(51)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(51)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of March 31, 2021</span></div></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(748)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(73)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(13)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(833)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency translation adjustments</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Unrealized losses</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(31)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(31)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Reclassification adjustments to income</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(28)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(28)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">11&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">11&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of June 30, 2021</span></div></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(734)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(121)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(14)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(868)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency translation adjustments</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(35)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(35)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Unrealized gains (losses)</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">16&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Reclassification adjustments to income</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">109&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">109&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(3)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(3)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(26)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(26)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of September 30, 2021</span></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(769)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(22)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(17)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(808)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:8pt;margin-top:7pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Reclassifications out of AOCI and into earnings, including related income tax expenses, were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:39.104%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:14.543%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:14.543%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:25.220%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended September 30,</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Components of AOCI</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Statements of Income locations</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash flow hedges:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contract (losses) gains</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(5)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">41&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Product sales</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contract (losses) gains</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(104)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">183&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income, net</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(109)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">224&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income before income taxes</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">23&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(49)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Provision for income taxes</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(86)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">175&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Available-for-sale securities:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net realized gains</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Provision for income taxes</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="9" style="background-color:#ffffff;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended September 30,</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Components of AOCI</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Statements of Income locations</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash flow hedges:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contract (losses) gains</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(24)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">158&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Product sales</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contract (losses) gains</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(190)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">101&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income, net</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(214)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">259&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income before income taxes</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">45&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(57)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Provision for income taxes</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(169)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">202&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Available-for-sale securities:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net realized gains</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(7)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Provision for income taxes</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">26&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td></tr></table></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EquityAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EquityAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockholdersEquityNoteDisclosureTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for shareholders' equity comprised of portions attributable to the parent entity and noncontrolling interest, including other comprehensive income. Includes, but is not limited to, balances of common stock, preferred stock, additional paid-in capital, other capital and retained earnings, accumulated balance for each classification of other comprehensive income and amount of comprehensive income.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 13<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=SL123496158-112644<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 13<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=SL123496158-112644<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 14<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=SL123496171-112644<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 14<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=SL123496171-112644<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -URI http://asc.fasb.org/extlink&amp;oid=120397183&amp;loc=d3e187085-122770<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 18<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=SL123496189-112644<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 13<br> -Subparagraph (g)<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=SL123496158-112644<br><br>Reference 8: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -URI http://asc.fasb.org/topic&amp;trid=2208762<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 18<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=SL123496189-112644<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 13<br> -Subparagraph (h)<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=SL123496158-112644<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 14<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=SL123496171-112644<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 18<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=SL123496189-112644<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 16<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=SL123496180-112644<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 13<br> -Subparagraph (i)<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=SL123496158-112644<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(e)(1))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockholdersEquityNoteDisclosureTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>30
<FILENAME>R20.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304047630040">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Fair value measurement<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueDisclosuresAbstract', window );"><strong>Fair Value Disclosures [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueDisclosuresTextBlock', window );">Fair value measurement</a></td>
<td class="text">Fair value measurement<div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">To estimate the fair value of our financial assets and liabilities, we use valuation approaches within a hierarchy that maximizes the use of observable inputs and minimizes the use of unobservable inputs by requiring that observable inputs be used when available. Observable inputs are inputs that market participants would use in pricing an asset or liability based on market data obtained from sources independent of the Company. Unobservable inputs are inputs that reflect the Company&#8217;s assumptions about the inputs that market participants would use in pricing an asset or liability and are developed based on the best information available in the circumstances. The fair value hierarchy is divided into three levels based on the source of inputs as follows:</span></div><div style="margin-bottom:1pt;text-align:center;text-indent:22.5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:98.391%"><tr><td style="width:1.0%"/><td style="width:6.180%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:2.177%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:89.243%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Level&#160;1</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;</span></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Valuations based on unadjusted quoted prices in active markets for identical assets or liabilities that the Company has the ability to access</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Level&#160;2</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;</span></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Valuations for which all significant inputs are observable either directly or indirectly&#8212;other than Level 1 inputs</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Level&#160;3</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;</span></td><td colspan="3" style="padding:2px 1pt;text-align:justify;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Valuations based on inputs that are unobservable and significant to the overall fair value measurement</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The availability of observable inputs can vary among different types of financial assets and liabilities. To the extent that the valuation is based on models or inputs that are less observable or unobservable in the market, the determination of fair value requires more judgment. In certain cases, the inputs used for measuring fair value may fall into different levels of the fair value hierarchy. In such cases, for financial statement disclosure purposes, the level in the fair value hierarchy within which the fair value measurement is categorized is based on the lowest level of input used that is significant to the overall fair value measurement.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of each major class of the Company&#8217;s financial assets and liabilities measured at fair value on a recurring basis were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:40.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.788%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.788%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.788%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.796%"/><td style="width:0.1%"/></tr><tr style="height:12pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Quoted&#160;prices in<br/>active&#160;markets&#160;for<br/>identical assets<br/>(Level 1)</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Significant<br/>other&#160;observable<br/>inputs<br/>(Level 2)</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Significant<br/>unobservable<br/>inputs<br/>(Level 3)</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr style="height:12pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr style="height:12pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair value measurement as of September 30, 2021, using:</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Assets:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Available-for-sale securities:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">51&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">51&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury bills</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,900&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,900&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Money market mutual funds</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">8,323&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">8,323&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other short-term interest-bearing securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Equity securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">608&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">257&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">865&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">127&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">127&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">119&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">119&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">29&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">29&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,882&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">276&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">257&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13,415&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Liabilities:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">54&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">54&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">360&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">360&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">105&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">105&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Contingent consideration obligations</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">35&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">35&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total liabilities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">519&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">35&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">554&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:40.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.788%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.788%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.788%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.796%"/><td style="width:0.1%"/></tr><tr style="height:11pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Quoted&#160;prices in<br/>active&#160;markets&#160;for<br/>identical assets<br/>(Level 1)</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Significant<br/>other observable<br/>inputs<br/>(Level 2)</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Significant<br/>unobservable<br/>inputs<br/>(Level 3)</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr style="height:12pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr style="height:15pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair value measurement as of December 31, 2020, using:</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Assets:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Available-for-sale securities:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">130&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">130&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury bills</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,948&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,948&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Money market mutual funds</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,765&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,765&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other short-term interest-bearing securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Equity securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">477&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">477&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">28&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">28&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">255&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">255&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">66&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">66&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10,320&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">351&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10,671&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Liabilities:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">237&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">237&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">318&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">318&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Contingent consideration obligations</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total liabilities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">570&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">603&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="text-align:justify"><span><br/></span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Interest-bearing and equity securities</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of our U.S. Treasury securities, money market mutual funds and equity investments in publicly traded securities are based on quoted market prices in active markets, with no valuation adjustment. The fair value of equity securities without readily determinable fair values are initially valued at the transaction price and subsequently valued based upon a combination of entity-specific financial information and publicly available market information for similar companies that have actively traded equity securities.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Derivatives</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">All of our foreign currency forward derivative contracts have maturities of three years or less, and all are with counterparties that have minimum credit ratings of A&#8211; or equivalent by Standard &amp; Poor&#8217;s Financial Services LLC (S&amp;P), Moody&#8217;s Investors Service, Inc. (Moody&#8217;s) or Fitch Ratings, Inc. (Fitch). We estimate the fair values of these contracts by taking into consideration valuations obtained from a third-party valuation service that uses an income-based industry-standard valuation model for which all significant inputs are observable either directly or indirectly. These inputs include foreign currency exchange rates, LIBOR, swap rates and obligor credit default swap rates. In addition, inputs for our foreign currency option contracts include implied volatility measures. These inputs, when applicable, are at commonly quoted intervals. See Note 13, Derivative instruments.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our cross-currency swap contracts are with counterparties that have minimum credit ratings of A&#8211; or equivalent by S&amp;P, Moody&#8217;s or Fitch. We estimate the fair values of these contracts by taking into consideration valuations obtained from a third-party valuation service that uses an income-based industry-standard valuation model for which all significant inputs are observable either directly or indirectly. These inputs include foreign currency exchange rates, LIBOR, swap rates, obligor credit default swap rates and cross-currency-basis swap spreads. See Note 13, Derivative instruments.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our interest rate swap contracts are with counterparties that have minimum credit ratings of A&#8211; or equivalent by S&amp;P, Moody&#8217;s or Fitch. We estimate the fair values of these contracts by using an income-based industry-standard valuation model for which all significant inputs are observable either directly or indirectly. These inputs include LIBOR, swap rates and obligor credit default swap rates. See Note 13, Derivative instruments.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">During the three and nine months ended September 30, 2021 and 2020, there were no material remeasurements to the fair values of assets and liabilities that are not measured at fair value on a recurring basis.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Summary of the fair values of other financial instruments</span></div><div style="margin-bottom:8pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Cash equivalents</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of cash equivalents approximate their carrying values due to the short-term nature of such financial instruments.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Borrowings</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We estimated the fair values of our borrowings by using Level 2 inputs. As of September 30, 2021 and December 31, 2020, the aggregate fair values of our borrowings were $42.2 billion and $39.4 billion, respectively, and the carrying values were $37.6 billion and $33.0 billion, respectively.</span></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FairValueDisclosuresAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FairValueDisclosuresAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FairValueDisclosuresTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for the fair value of financial instruments (as defined), including financial assets and financial liabilities (collectively, as defined), and the measurements of those instruments as well as disclosures related to the fair value of non-financial assets and liabilities. Such disclosures about the financial instruments, assets, and liabilities would include: (1) the fair value of the required items together with their carrying amounts (as appropriate); (2) for items for which it is not practicable to estimate fair value, disclosure would include: (a) information pertinent to estimating fair value (including, carrying amount, effective interest rate, and maturity, and (b) the reasons why it is not practicable to estimate fair value; (3) significant concentrations of credit risk including: (a) information about the activity, region, or economic characteristics identifying a concentration, (b) the maximum amount of loss the entity is exposed to based on the gross fair value of the related item, (c) policy for requiring collateral or other security and information as to accessing such collateral or security, and (d) the nature and brief description of such collateral or security; (4) quantitative information about market risks and how such risks are managed; (5) for items measured on both a recurring and nonrecurring basis information regarding the inputs used to develop the fair value measurement; and (6) for items presented in the financial statement for which fair value measurement is elected: (a) information necessary to understand the reasons for the election, (b) discussion of the effect of fair value changes on earnings, (c) a description of [similar groups] items for which the election is made and the relation thereof to the balance sheet, the aggregate carrying value of items included in the balance sheet that are not eligible for the election; (7) all other required (as defined) and desired information.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 820<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=123874694&amp;loc=d3e19207-110258<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FairValueDisclosuresTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>31
<FILENAME>R21.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304045834840">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Derivative instruments<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract', window );"><strong>Derivative Instruments and Hedging Activities Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock', window );">Derivative instruments</a></td>
<td class="text">Derivative instruments<div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The Company is exposed to foreign currency exchange rate and interest rate risks related to its business operations. To reduce our risks related to such exposures, we use or have used certain derivative instruments, including foreign currency forward, cross-currency swap, forward interest rate and interest rate swap contracts. We do not use derivatives for speculative- trading purposes.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Cash flow hedges</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We are exposed to possible changes in the values of certain anticipated foreign currency cash flows resulting from changes in foreign currency exchange rates primarily associated with our euro-denominated international product sales. Increases and decreases in the cash flows associated with our international product sales due to movements in foreign currency exchange rates are partially offset by corresponding increases and decreases in the cash flows from our international operating expenses resulting from these foreign currency exchange rate movements. To further reduce our exposure to foreign currency exchange rate fluctuations with regard to our international product sales, we enter into foreign currency forward contracts to hedge a portion of our projected international product sales up to a maximum of three years into the future; and at any given point in time, a higher percentage of nearer-term projected product sales are being hedged than in successive periods.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">As of September 30, 2021 and December 31, 2020, we had outstanding foreign currency forward contracts with aggregate notional amounts of $5.7 billion and $5.1 billion, respectively. We have designated these foreign currency forward contracts, which are primarily euro based, as cash flow hedges. Accordingly, we report the unrealized gains and losses on these contracts in AOCI in the Condensed Consolidated Balance Sheets, and we reclassify them to Product sales in the Condensed Consolidated Statements of Income in the same periods during which the hedged transactions affect earnings.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">To hedge our exposure to foreign currency exchange rate risk associated with certain of our long-term debt denominated in foreign currencies, we enter into cross-currency swap contracts. Under the terms of such contracts, we paid euros, pounds sterling and Swiss francs and received U.S. dollars for the notional amounts at the inception of the contracts; and based on these notional amounts, we exchange interest payments at fixed rates over the lives of the contracts by paying U.S. dollars and receiving euros, pounds sterling and Swiss francs. In addition, we will pay U.S. dollars to and receive euros, pounds sterling and Swiss francs from the counterparties at the maturities of the contracts for these same notional amounts. The terms of these contracts correspond to the related hedged debt, thereby effectively converting the interest payments and principal repayment on the debt from euros, pounds sterling and Swiss francs to U.S. dollars. We have designated these cross-currency swap contracts as cash flow hedges. Accordingly, the unrealized gains and losses on these contracts are reported in AOCI in the Condensed Consolidated Balance Sheets and reclassified to Other income, net, in the Condensed Consolidated Statements of Income in the same periods during which the hedged debt affects earnings.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The notional amounts and interest rates of our cross-currency swaps as of September 30, 2021, were as follows (notional amounts in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:29.894%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.426%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Foreign currency</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S. dollars</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Hedged notes</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Notional amounts</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest rates</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Notional amounts</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest rates</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1.25% 2022 euro Notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8364;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1.3&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,388&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.2&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">0.41% 2023 Swiss franc Bonds</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">CHF</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">700&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">0.4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">704&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.00% 2026 euro Notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8364;</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">750&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.0&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">833&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.9&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.50% 2026 pound sterling Notes</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#163;</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">475&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.5&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">747&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.0&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.00% 2029 pound sterling Notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#163;</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">700&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.0&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,111&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.5&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#231f20;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In connection with the anticipated issuance of long-term fixed-rate debt, we occasionally enter into forward interest rate contracts in order to hedge the variability in cash flows due to changes in the applicable U.S. Treasury rate between the time we enter into these contracts and the time the related debt is issued. Gains and losses on forward interest rate contracts, which are designated as cash flow hedges, are recognized in AOCI i</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">n the Condensed Consolidated Balance Sheets </span><span style="color:#231f20;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">and are amortized into Interest expense, net, in the Condensed Consolidated Statements of Income over the lives of the associated debt issuances. Amounts recognized in connection with forward interest rate swaps during the nine months ended September 30, 2021, and amounts expected to be recognized during the subsequent 12 months are not material.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The unrealized gains and losses recognized in AOCI for our derivative instruments designated as cash flow hedges were as follows (in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:45.245%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.619%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.619%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.473%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.624%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivatives in cash flow hedging relationships</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">136&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(163)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">273&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(25)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(120)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">223&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(180)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(107)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 14.5pt;text-align:left;text-indent:-4.5pt;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total unrealized gains (losses)</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">16&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">60&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">93&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(132)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Fair value hedges</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">To achieve a desired mix of fixed-rate and floating-rate debt, we entered into interest rate swap contracts that qualified for and were designated as fair value hedges. These interest rate swap contracts effectively convert fixed-rate coupons to floating-rate LIBOR-based coupons over the terms of the related hedge contracts. As of September 30, 2021 and December 31, 2020, we had interest rate swap contracts with aggregate notional amounts of $7.4&#160;billion and $5.9 billion, respectively, that hedge certain portions of our long-term debt issuances. During the three months ended June 30, 2021, we entered into $1.5&#160;billion of interest rate swap contracts to hedge portions of our 2.45% 2030 Notes and 2.30% 2031 Notes (see Note 10, Financing arrangements).</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">For interest rate swap contracts that qualify for and are designated as fair value hedges, we recognize in Interest expense, net, in the Condensed Consolidated Statements of Income the unrealized gain or loss on the derivative resulting from the change in fair value during the period, as well as the offsetting unrealized loss or gain of the hedged item resulting from the change in fair value during the period attributable to the hedged risk. If a hedging relationship involving an interest rate swap contract is terminated, the gain or loss realized on contract termination is recorded as an adjustment to the carrying value of the debt and amortized into Interest expense, net, over the remaining life of the previously hedged debt.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The hedged liabilities and related cumulative-basis adjustments for fair value hedges of those liabilities were recorded in the Condensed Consolidated Balance Sheets as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:37.496%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:13.519%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:13.519%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:13.519%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:13.527%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Carrying amounts of hedged liabilities</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:5.2pt;font-weight:700;line-height:100%;position:relative;top:-2.8pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Cumulative amounts of fair value hedging adjustments related to the carrying amounts of the hedged liabilities</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:5.2pt;font-weight:700;line-height:100%;position:relative;top:-2.8pt;vertical-align:baseline">(2)</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated Balance Sheets locations</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Current portion of long-term debt</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">840&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">89&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">90&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">89&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Long-term debt</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,809&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,258&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">281&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">477&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-top:7pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">____________</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> &#160;&#160;&#160;&#160;Current portion of long-term debt includes $87 million and $89&#160;million of carrying value with discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively. Long-term debt includes $460 million and $525 million of carrying value with discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively.</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">(2)</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;Current portion of long-term debt includes $87 million and $89&#160;million of hedging adjustments on discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively. Long-term debt includes $360 million and $425 million of hedging adjustments on discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively.</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Impact of hedging transactions</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The following tables summarize the amounts recorded in income and expense line items and the effects thereon from fair value and cash flow hedging, including discontinued hedging relationships (in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.561%"><tr><td style="width:1.0%"/><td style="width:40.309%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:7.710%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:7.710%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.151%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:7.710%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.151%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.155%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended September 30, 2021</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Product sales</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other income, net</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest expense, net</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Product sales</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other income, net</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest expense, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total amounts recorded in income and (expense) line items presented in the Condensed Consolidated Statements of Income</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,320&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">73&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(296)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18,026&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">97&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(862)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">The effects of cash flow and fair value hedging:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Losses on cash flow hedging relationships reclassified out of AOCI:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(5)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(24)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(104)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(190)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Gains (losses) on fair value hedging relationships&#8212;interest rate swap agreements:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:11.25pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Hedged items</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">54&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">195&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives designated as hedging instruments</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(31)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(128)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span><br/></span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.561%"><tr><td style="width:1.0%"/><td style="width:40.309%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:7.710%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.151%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.151%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:7.710%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:7.710%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.155%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended September 30, 2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended September 30, 2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Product sales</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other income, net</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest expense, net</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Product sales</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other income, net</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest expense, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total amounts recorded in income and (expense) line items presented in the Condensed Consolidated Statements of Income</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,104&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">55&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(302)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">17,906&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">69&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(944)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">The effects of cash flow and fair value hedging:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Gains on cash flow hedging relationships reclassified out of AOCI:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">41&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">158&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">183&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">101&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Gains (losses) on fair value hedging relationships&#8212;interest rate swap agreements:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:11.25pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Hedged items</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">35&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">215&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives designated as hedging instruments</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(13)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(150)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">__________</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;Gains on hedged items do not exactly offset losses on the related designated hedging instruments due to amortization of the cumulative amounts of fair value hedging adjustments included in the carrying amount of the hedged debt for discontinued hedging relationships and the recognition of gains on terminated hedges when the corresponding hedged item was paid down in the period.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">No portions of our cash flow hedge contracts were excluded from the assessment of hedge effectiveness. As of September 30, 2021, the net gains expected to be reclassified on our foreign currency and cross-currency swap contracts out of AOCI and into earnings during the next 12 months are not material.</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Derivatives not designated as hedges</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">To reduce our exposure to foreign currency fluctuations in certain assets and liabilities denominated in foreign currencies, we enter into foreign currency forward contracts that are not designated as hedging transactions. Most of these exposures are hedged on a month-to-month basis. As of September 30, 2021 and December 31, 2020, the total notional amounts of these foreign currency forward contracts were $0.7 billion and $1.0 billion, respectively. Gains and losses recognized in earnings for our derivative instruments not designated as hedging instruments were not material for the three and nine months ended September 30, 2021 and 2020. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of derivatives included in the Condensed Consolidated Balance Sheets were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:37.496%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:18.344%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.695%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:18.344%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.701%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivative assets</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivative liabilities</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Balance Sheets locations</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair&#160;values</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Balance Sheets locations</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair&#160;values</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivatives designated as hedging&#160;instruments:</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">127&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other&#160;noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">54&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">119&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other&#160;noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">360&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">29&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other&#160;noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">105&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total derivatives designated as hedging instruments</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">275&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">519&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div><span><br/></span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:37.496%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:18.344%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.695%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:18.344%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.701%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivative assets</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivative liabilities</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Balance Sheets locations</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair&#160;values</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Balance Sheets locations</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair&#160;values</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivatives designated as hedging instruments:</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">28&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">237&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">255&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">318&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">66&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total derivatives designated as hedging instruments</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">349&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">570&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our derivative contracts that were in liability positions as of September 30, 2021, contain certain credit-risk-related contingent provisions that would be triggered if (i)&#160;we were to undergo a change in control and (ii)&#160;our or the surviving entity&#8217;s creditworthiness deteriorates, which is generally defined as having either a credit rating that is below investment grade or a materially weaker creditworthiness after the change in control. If these events were to occur, the counterparties would have the right, but not the obligation, to close the contracts under early-termination provisions. In such circumstances, the counterparties could request immediate settlement of these contracts for amounts that approximate the then current fair values of the contracts. In addition, our derivative contracts are not subject to any type of master netting arrangement, and amounts due either to or from a counterparty under the contracts may be offset against other amounts due either to or from the same counterparty only if an event of default or termination, as defined, were to occur.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The cash flow effects of our derivative contracts in the Condensed Consolidated Statements of Cash Flows are included in Net cash provided by operating activities, except for the settlement of notional amounts of cross-currency swaps, which are included in Net cash used in financing activities.</span></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for derivative instruments and hedging activities including, but not limited to, risk management strategies, non-hedging derivative instruments, assets, liabilities, revenue and expenses, and methodologies and assumptions used in determining the amounts.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -URI http://asc.fasb.org/topic&amp;trid=2229140<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 50<br> -Paragraph 5<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123477628&amp;loc=d3e90205-114008<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>32
<FILENAME>R22.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304045810440">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Contingencies and commitments<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommitmentsAndContingenciesDisclosureAbstract', window );"><strong>Commitments and Contingencies Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock', window );">Contingencies and commitments</a></td>
<td class="text">Contingencies and commitments<div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Contingencies</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In the ordinary course of business, we are involved in various legal proceedings, government investigations and other matters that are complex in nature and have outcomes that are difficult to predict. See our Annual Report on Form 10-K for the year ended December 31, 2020, Part I, Item 1A. Risk Factors&#8212;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Our business may be affected by litigation and government investigations. </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We describe our legal proceedings and other matters that are significant or that we believe could become significant in this footnote; in Note 19, Contingencies and commitments, to the consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2020; in Note 12, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended March 31, 2021; and in Note 13, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended June 30, 2021.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">We record accruals for loss contingencies to the extent that we conclude it is probable that a liability has been incurred and the amount of the related loss can be reasonably estimated. We evaluate, on a quarterly basis, developments in legal proceedings and other matters that could cause an increase or decrease in the amount of the liability that has been accrued previously.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our legal proceedings involve various aspects of our business and a variety of claims, some of which present novel factual allegations and/or unique legal theories. In each of the matters described in this filing; in Note 19, Contingencies and commitments, to the consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2020; in Note 12, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended March 31, 2021; or in Note 13, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended June 30, 2021, in which we could incur a liability, our opponents seek an award of a not-yet-quantified amount of damages or an amount that is not material. In addition, a number of the matters pending against us are at very early stages of the legal process, which in complex proceedings of the sort we face often extend for several years. As a result, none of the matters described in this filing; in Note 19, Contingencies and commitments, to the consolidated financial statements in our Annual Report on Form 10-K for the year ended December 31, 2020; in Note 12, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended March 31, 2021; or in Note 13, Contingencies and commitments, to the condensed consolidated financial statements in our Quarterly Report on Form 10-Q for the period ended June 30, 2021, in which we could incur a liability, have progressed sufficiently through discovery and/or the development of important factual information and legal issues to enable us to estimate a range of possible loss, if any, or such amounts are not material. While it is not possible to accurately predict or determine the eventual outcomes of these matters, an adverse determination in one or more of these matters currently pending could have a material adverse effect on our consolidated results of operations, financial position or cash flows.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Certain recent developments concerning our legal proceedings and other matters are discussed below:</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Abbreviated New Drug Application (ANDA) Patent Litigation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"> ANDA Patent Litigation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Amgen Inc. v. Sandoz Inc., et al.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On September 28, 2021, consistent with its September 20, 2021 opinion and order, the U.S. District Court for the District of New Jersey (the New Jersey District Court) entered final judgment in favor of Amgen and against Zydus Pharmaceuticals (USA) Inc. (Zydus) with respect to claims 3 and 6 of U.S. Patent No. 7,427,638 (the &#8217;638 Patent), claim 6 of U.S. Patent No. 8,455,536 (the &#8217;536 Patent) and claims 2 and 27 of U.S. Patent No. 8,093,283 (the &#8216;283 Patent); and final judgment in favor of Zydus and against Amgen with respect to claims 1 and 15 of U.S. Patent No. 7,893,101 (the &#8216;101 Patent) and claims 2, 19 and 21 of U.S. Patent No. 10,092,541 (the &#8217;541 Patent). The final judgment ordered that the effective date of any final approval by the U.S. Food and Drug Administration (FDA) of Zydus&#8217;s ANDA must be after expiration of the three infringed patents (the &#8217;638, &#8217;536 and &#8217;283 Patents) and any regulatory exclusivity to which Amgen may become entitled. The final judgment also includes an injunction prohibiting Zydus from making, using, offering to sell, or selling in the United States, or importing into the United States, Zydus&#8217;s generic apremilast products during the term of the three infringed patents. </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On October 12, 2021, the New Jersey District Court also entered final judgment in favor of Amgen and against Sandoz Inc. (Sandoz) with respect to claims 3 and 6 of the &#8217;638 Patent, claim 6 of the &#8217;536 Patent and claims 1 and 15 of the &#8217;101 Patent; and final judgment in favor of Sandoz and against Amgen with respect to claims 2, 19 and 21 of the &#8217;541 Patent. The final judgment ordered that the effective date of any final approval by the FDA of Sandoz&#8217;s ANDA must be after expiration of the three infringed patents (the &#8217;638, &#8217;536 and &#8217;101 Patents) and any regulatory exclusivity to which Amgen may become entitled. The final judgment also includes an injunction prohibiting Sandoz from making, using, offering to sell, or selling in the United States, or importing into the United States, Sandoz&#8217;s generic apremilast products during the term of the three infringed patents.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Zydus and Amgen filed notices of appeal to the U.S. Court of Appeals for the Federal Circuit (the Federal Circuit Court) on October 27, 2021 and October 28, 2021, respectively.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Sensipar</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">(cinacalcet) ANDA Patent Litigation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Amgen Inc. v. Amneal Pharmaceuticals LLC, et al. (formerly, Amgen Inc. v. Aurobindo Pharma Ltd. et al.) </span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On October 20, 2021, the U.S. District Court for the District of Delaware (the Delaware District Court) issued final judgment in favor of Piramal Healthcare UK Limited and Slate Run Pharmaceuticals LLC.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">ENBREL Patent Litigation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Immunex Corporation, et al. v. Samsung Bioepis Co., Ltd.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On November 2, 2021, Amgen and Samsung Bioepis Co., Ltd. (Bioepis), with the consent of Hoffmann-La Roche Inc. (Roche), jointly submitted to the New Jersey District Court a confidential stipulation and a form of final judgment and order of permanent injunction resolving the dispute between the parties and enjoining Bioepis from making, using, offering to sell, or selling within the United States, or importing into the United States, any product containing etanercept until the April 24, 2029 expiry of Roche&#8217;s U.S. Patent No. 8,163,522.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"> Patent Litigation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Patent Disputes in the International Region</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">National litigations in the United Kingdom, France, the Netherlands and Italy have been settled. In Germany, Sanofi-Aventis Deutschland GmbH and Regeneron Pharmaceuticals, Inc. have filed actions claiming they are entitled to damages arising from the provisional enforcement of an injunction against PRALUENT</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.47pt;font-weight:400;line-height:120%;position:relative;top:-3.48pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">that was lifted after the European Patent Office Technical Board of Appeal&#8217;s October 29, 2020 ruling that certain claims encompassing PRALUENT</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.47pt;font-weight:400;line-height:120%;position:relative;top:-3.48pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> in Amgen&#8217;s European Patent No. 2,215,124 were invalid.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">NEUPOGEN</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"> (filgrastim)/Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-style:italic;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%"> Patent Litigation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Amgen Inc., et al. v. Pfizer Inc. et al.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On September 8, 2021, pursuant to joint stipulation, the Delaware District Court dismissed the lawsuits regarding U.S. Patent Nos. 9,643,997 and 10,577,392.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Patent Trial and Appeal Board (PTAB) Challenge</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Apotex PTAB Challenge</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On September 2, 2021, the Federal Circuit Court issued a remand to permit Amgen to request rehearing of the PTAB&#8217;s final written decision holding that all claims of U.S. Patent No. 8.952,138 as unpatentable.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Pfizer PTAB Challenge</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On February 10, 2021, Hospira, Inc. and Pfizer Inc. (collectively, Pfizer) filed a petition to institute inter partes review (IPR) proceeding at the U.S. Patent and Trademark Office (USPTO) of U.S. Patent No. 8,273,707 (the &#8217;707 Patent), challenging claims of the &#8217;707 Patent as unpatentable. Amgen&#8217;s preliminary response was filed on May 18, 2021.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On August 17, 2021, the PTAB of the USPTO granted Pfizer&#8217;s petition to institute IPR of the &#8217;707 Patent. On August 23, 2021, the PTAB issued the schedule for the proceeding, including oral argument (if requested) on May 18, 2022. </span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Breach of Contract Action</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Novartis Pharma AG v. Amgen Inc.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On October 26, 2021, the U.S. District Court for the Southern District of New York held a status conference with the parties and set the dates for Novartis Pharma AG&#8217;s (Novartis) opening brief for its motion for partial summary judgment on two claims, fraudulent inducement and negligent misrepresentation, to be due on January 14, 2022, Amgen&#8217;s opposition to be due on February 14, 2022 and Novartis&#8217; reply to be due on March 10, 2022. This motion, if granted, will not dispose of the entire case as other claims related to breach of contract remain pending.</span></div><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">U.S. Tax Litigation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Amgen Inc. &amp; Subsidiaries v. Commissioner of Internal Revenue</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">See Note 4, Income taxes, for discussion of the IRS tax dispute and the Company&#8217;s petition in the U.S. Tax Court.</span></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommitmentsAndContingenciesDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommitmentsAndContingenciesDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for commitments and contingencies.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 450<br> -URI http://asc.fasb.org/topic&amp;trid=2127136<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 440<br> -URI http://asc.fasb.org/topic&amp;trid=2144648<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 954<br> -SubTopic 440<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=6491277&amp;loc=d3e6429-115629<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 440<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123406679&amp;loc=d3e25336-109308<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 440<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123406679&amp;loc=d3e25336-109308<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommitmentsAndContingenciesDisclosureTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>33
<FILENAME>R23.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304047161784">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Subsequent events<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_SubsequentEventsAbstract', window );"><strong>Subsequent Events [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_SubsequentEventsTextBlock', window );">Subsequent events</a></td>
<td class="text">Subsequent event<div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On October 19, 2021, Amgen completed its acquisition of Teneobio, Inc. (Teneobio), a privately held, clinical-stage biotechnology company developing a new class of biologics called heavy-chain only antibodies (HCAbs). Amgen acquired all outstanding shares in exchange for a $900&#160;million upfront payment, as well as future contingent milestone payments potentially worth up to an additional $1.6&#160;billion in cash upon the achievement of certain development and regulatory events.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The accounting impact of this acquisition and the results of operations for Teneobio will be included in our consolidated financial statements beginning in the fourth quarter of 2021. The initial accounting for this acquisition is incomplete, pending identification and measurement of the assets acquired and liabilities assumed.</span></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SubsequentEventsAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SubsequentEventsAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SubsequentEventsTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The entire disclosure for significant events or transactions that occurred after the balance sheet date through the date the financial statements were issued or the date the financial statements were available to be issued. Examples include: the sale of a capital stock issue, purchase of a business, settlement of litigation, catastrophic loss, significant foreign exchange rate changes, loans to insiders or affiliates, and transactions not in the ordinary course of business.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 855<br> -URI http://asc.fasb.org/topic&amp;trid=2122774<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 855<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=6842918&amp;loc=SL6314017-165662<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SubsequentEventsTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>34
<FILENAME>R24.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051225192">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Summary of significant accounting policies (Policies)<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AccountingPoliciesAbstract', window );"><strong>Accounting Policies [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_NatureOfOperationsPolicyTextBlock', window );">Business</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Business</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Amgen Inc. (including its subsidiaries, referred to as &#8220;Amgen,&#8221; &#8220;the Company,&#8221; &#8220;we,&#8221; &#8220;our&#8221; or &#8220;us&#8221;) is a global biotechnology pioneer that discovers, develops, manufactures and delivers innovative human therapeutics.&#160;We operate in one business segment: human therapeutics.</span></div><span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_BasisOfPresentationPolicyTextBlock', window );">Basis of presentation</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Basis of presentation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The financial information for the three and nine months ended September 30, 2021 and 2020, is unaudited but includes all adjustments (consisting of only normal, recurring adjustments unless otherwise indicated), which Amgen considers necessary for a fair presentation of its condensed consolidated results of operations for those periods. Interim results are not necessarily indicative of results for the full fiscal year.</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The condensed consolidated financial statements should be read in conjunction with our consolidated financial statements and the notes thereto contained in our Annual Report on Form 10-K for the year ended December 31, 2020, and with our condensed consolidated financial statements and the notes thereto contained in our Quarterly Reports on Form 10-Q for the periods ended March 31, 2021 and June 30, 2021.</span></div><span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ConsolidationPolicyTextBlock', window );">Principles of consolidation</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Principles of consolidation</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The condensed consolidated financial statements include the accounts of Amgen as well as its majority-owned subsidiaries. We do not have any significant interests in any</span><span style="color:#ff0000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">variable interest entities. All material intercompany transactions and balances have been eliminated in consolidation.</span></div><span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_UseOfEstimates', window );">Use of estimates</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Use of estimates</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The preparation of condensed consolidated financial statements in conformity with U.S. generally accepted accounting principles (GAAP) requires management to make estimates and assumptions that affect the amounts reported in the condensed consolidated financial statements and accompanying notes. Actual results may differ from those estimates.</span></div><span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock', window );">Property, plant and equipment, net</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Property, plant and equipment, net</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Property, plant and equipment is recorded at historical cost, net of accumulated depreciation and amortization of $9.2&#160;billion and $9.0 billion as of September 30, 2021 and December 31, 2020, respectively.</span></div><span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock', window );">Other recent accounting pronouncements</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:400;line-height:120%">Recent accounting pronouncements</span></div><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In March 2020, the Financial Accounting Standards Board (FASB) issued a new accounting standard to ease the financial reporting burdens caused by the expected market transition from the London Interbank Offered Rate (LIBOR) and other interbank offered rates to alternative reference rates, commonly referred to as reference rate reform. The new standard provides temporary optional expedients and exceptions to current GAAP guidance on contract modifications and hedge accounting. Specifically, a modification to transition to an alternative reference rate is treated as an event that does not require contract remeasurement or reassessment of a previous accounting treatment. Moreover, for all types of hedging relationships, an entity is permitted to change the reference rate without having to dedesignate the hedging relationship. The standard is generally effective for all contract modifications made and hedging relationships evaluated through December 31, 2022. In January 2021, the FASB issued a new accounting standard to expand on the scope of the original March 2020 standard to include derivative instruments on discounting transactions. We are currently evaluating the impacts that the two standards will have on our condensed consolidated financial statements.</span></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_BasisOfPresentationPolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Shows the basis of presentation of financial information for interim periods.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_BasisOfPresentationPolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_NatureOfOperationsPolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Describes the nature of an entity's business, the major products or services it sells or provides and its principal markets, including the locations of those markets. If the entity operates in more than one business, the disclosure also indicates the relative importance of its operations in each business and the basis for the determination (for example, assets, revenues, or earnings). Disclosures about the nature of operations need not be quantified; relative importance could be conveyed by use of terms such as "predominately", "about equally", or "major and other". This element is also referred to as "Business Description".</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_NatureOfOperationsPolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccountingPoliciesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccountingPoliciesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ConsolidationPolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy regarding (1) the principles it follows in consolidating or combining the separate financial statements, including the principles followed in determining the inclusion or exclusion of subsidiaries or other entities in the consolidated or combined financial statements and (2) its treatment of interests (for example, common stock, a partnership interest or other means of exerting influence) in other entities, for example consolidation or use of the equity or cost methods of accounting.  The accounting policy may also address the accounting treatment for intercompany accounts and transactions, noncontrolling interest, and the income statement treatment in consolidation for issuances of stock by a subsidiary.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123372394&amp;loc=d3e18823-107790<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=109239629&amp;loc=d3e5614-111684<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ConsolidationPolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy pertaining to new accounting pronouncements that may impact the entity's financial reporting. Includes, but is not limited to, quantification of the expected or actual impact.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 958<br> -SubTopic 360<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=120429125&amp;loc=d3e99779-112916<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.13(a))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 958<br> -SubTopic 360<br> -Section 50<br> -Paragraph 6<br> -URI http://asc.fasb.org/extlink&amp;oid=120429125&amp;loc=d3e99893-112916<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 360<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=6391035&amp;loc=d3e2868-110229<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PropertyPlantAndEquipmentPolicyTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_UseOfEstimates">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Disclosure of accounting policy for the use of estimates in the preparation of financial statements in conformity with generally accepted accounting principles.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 275<br> -SubTopic 10<br> -Section 50<br> -Paragraph 12<br> -URI http://asc.fasb.org/extlink&amp;oid=99393423&amp;loc=d3e6191-108592<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 275<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -URI http://asc.fasb.org/extlink&amp;oid=99393423&amp;loc=d3e6161-108592<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 275<br> -SubTopic 10<br> -Section 50<br> -Paragraph 9<br> -URI http://asc.fasb.org/extlink&amp;oid=99393423&amp;loc=d3e6143-108592<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 275<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=99393423&amp;loc=d3e5967-108592<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 275<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=99393423&amp;loc=d3e6061-108592<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 275<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -URI http://asc.fasb.org/extlink&amp;oid=99393423&amp;loc=d3e6132-108592<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 275<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=99393423&amp;loc=d3e5967-108592<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_UseOfEstimates</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>35
<FILENAME>R25.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304045870424">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Revenues (Tables)<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerAbstract', window );"><strong>Revenue from Contract with Customer [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DisaggregationOfRevenueTableTextBlock', window );">Disaggregation of revenue by product and by geographic area</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Revenues were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:32.818%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.133%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.133%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.823%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.133%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.133%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.133%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.144%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="33" style="border-bottom:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended September 30,</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S.</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">ROW</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S.</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">ROW</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Enbrel</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(etanercept)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,263&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">26&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,289&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,289&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">36&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,325&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (denosumab)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">530&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">273&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">803&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">478&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">223&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">701&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(apremilast)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">495&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">114&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">609&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">439&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">99&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">538&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> (denosumab)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">372&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">145&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">517&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">363&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">118&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">481&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(pegfilgrastim)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">360&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">55&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">415&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">484&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">71&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">555&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(darbepoetin alfa)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">149&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">247&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">396&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">158&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">226&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">384&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(evolocumab)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">139&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">133&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">272&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">92&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">113&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">205&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174; </span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(carfilzomib)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">198&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">95&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">293&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">173&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">87&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">260&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other products</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,052&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">674&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,726&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,142&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">513&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,655&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total product sales</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,558&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,762&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,320&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,618&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,486&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,104&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other revenues</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">386&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">319&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total revenues</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,706&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,423&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:15pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="33" style="border-bottom:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended September 30,</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="15" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S.</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">ROW</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S.</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">ROW</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">ENBREL</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,270&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">87&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,357&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,619&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">105&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,724&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Prolia</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,569&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">806&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,375&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,341&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">673&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,014&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Otezla</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,284&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">335&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,619&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,280&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">298&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,578&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">XGEVA</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%"> </span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,061&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">412&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,473&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,036&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">361&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,397&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Neulasta</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,215&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">168&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,383&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,538&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">219&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,757&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Aranesp</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">409&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">709&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,118&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">489&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">704&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,193&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Repatha</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">421&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">423&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">844&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">331&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">303&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">634&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">KYPROLIS</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">&#174;</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">547&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">277&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">824&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">527&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">266&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">793&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other products</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,059&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,974&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5,033&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,164&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,652&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,816&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total product sales</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,835&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5,191&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18,026&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13,325&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,581&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">17,906&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other revenues</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,107&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">884&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total revenues</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">19,133&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18,790&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:15pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:3pt double #000000;padding:0 1pt"/></tr></table></div><div style="margin-top:4pt;padding-left:13.5pt;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">____________</span></div>(1)&#160;&#160;&#160;&#160;Hedging gains and losses, which are included in product sales, were not material for the three and nine months ended September 30, 2021 and 2020.<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DisaggregationOfRevenueTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of disaggregation of revenue into categories depicting how nature, amount, timing, and uncertainty of revenue and cash flows are affected by economic factor.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 5<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130545-203045<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DisaggregationOfRevenueTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_RevenueFromContractWithCustomerAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_RevenueFromContractWithCustomerAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>36
<FILENAME>R26.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304045859336">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Earnings per share (Tables)<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EarningsPerShareAbstract', window );"><strong>Earnings Per Share [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock', window );">Computation for basic and diluted earnings per share</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The computations for basic and diluted EPS were as follows (in millions, except per-share data):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:45.829%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.619%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.619%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.619%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.624%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:120%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income (Numerator):</span></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income for basic and diluted EPS</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,884&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,021&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,994&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5,649&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Shares (Denominator):</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Weighted-average shares for basic EPS</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">567&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">585&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">572&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">588&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Effect of dilutive securities</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Weighted-average shares for diluted EPS</span></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">570&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">589&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">576&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">592&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:15pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Basic EPS</span></td><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.32&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.45&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.98&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9.61&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Diluted EPS</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.31&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.43&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.93&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9.54&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EarningsPerShareAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EarningsPerShareAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of an entity's basic and diluted earnings per share calculations, including a reconciliation of numerators and denominators of the basic and diluted per-share computations for income from continuing operations.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124432515&amp;loc=d3e3550-109257<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>37
<FILENAME>R27.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304056103144">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Investments (Tables)<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract', window );"><strong>Investments, Debt and Equity Securities [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock', window );">Amortized cost, gross unrealized gains, gross unrealized losses and estimated fair values of available-for-sale investments by type of security</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The amortized cost, gross unrealized gains, gross unrealized losses and fair values of interest-bearing securities, which are considered available-for-sale, by type of security were as follows (in millions):</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:42.174%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.350%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.350%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.350%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.356%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Types of securities as of September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Amortized<br/>cost</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>unrealized<br/>gains</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>unrealized<br/>losses</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair<br/>values</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">51&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">51&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury bills</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,900&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,900&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Money market mutual funds</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">8,323&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">8,323&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other short-term interest-bearing securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total interest-bearing securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,275&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,275&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span><br/></span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:42.174%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.350%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.350%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.350%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.356%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Types of securities as of December 31, 2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Amortized<br/>cost</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>unrealized<br/>gains</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>unrealized<br/>losses</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair<br/>values</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">129&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">130&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury bills</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,948&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,948&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Money market mutual funds</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,765&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,765&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other short-term interest-bearing securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total interest-bearing securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9,844&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9,845&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock', window );">Fair values of available-for-sale investments by classification in the Consolidated Balance Sheets</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of interest-bearing securities by location in the Condensed Consolidated Balance Sheets were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:64.397%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.423%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated Balance Sheets locations</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash and cash equivalents</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">11,323&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5,464&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Marketable securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">952&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,381&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total interest-bearing securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,275&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9,845&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock', window );">Fair values of available-for-sale interest-bearing security investments by contractual maturity</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of available-for-sale investments by contractual maturity were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:64.397%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.423%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Contractual maturities</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Maturing in one year or less</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,275&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9,795&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Maturing after one year through three years</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">50&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total available-for-sale investments </span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,275&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9,845&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of fair values of available-for-sale investments by classification in the consolidated balance sheets.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -URI http://asc.fasb.org/topic&amp;trid=2196928<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of maturities of an entity's investments as well as any other information pertinent to the investments.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>38
<FILENAME>R28.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304055067416">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Inventories (Tables)<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InventoryDisclosureAbstract', window );"><strong>Inventory Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfInventoryCurrentTableTextBlock', window );">Inventories</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Inventories consisted of the following (in millions):</span></div><div><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:65.128%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.422%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Raw materials</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">667&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">486&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Work in process</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,313&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,437&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Finished goods</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,172&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">970&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 5.5pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total inventories</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,152&#160;</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,893&#160;</span></td><td style="border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InventoryDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InventoryDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfInventoryCurrentTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of the carrying amount as of the balance sheet date of merchandise, goods, commodities, or supplies held for future sale or to be used in manufacturing, servicing or production process.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(6)(c))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(6)(b))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(6)(a))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=6361739&amp;loc=d3e7789-107766<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfInventoryCurrentTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>39
<FILENAME>R29.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304047207544">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Goodwill and other intangible assets (Tables)<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract', window );"><strong>Goodwill and Intangible Assets Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfGoodwillTextBlock', window );">Schedule of goodwill</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The change in the carrying amount of goodwill was as follows (in millions):</span></div><div><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.707%"><tr><td style="width:1.0%"/><td style="width:82.331%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.469%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30, 2021</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Beginning balance</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14,689&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Currency translation adjustment</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(24)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Ending balance</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14,665&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_ScheduleOfIntangibleAssetsTableTextBlock', window );">Schedule of identifiable intangible assets</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Other intangible assets consisted of the following (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:32.087%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.426%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.426%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.426%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.426%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.426%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.433%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>carrying<br/>amounts</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Accumulated<br/>amortization</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other intangible<br/>assets, net</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Gross<br/>carrying<br/>amounts</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Accumulated<br/>amortization</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other intangible<br/>assets, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Finite-lived intangible assets:</span></td><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Developed-product-technology rights</span></td><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">25,575&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(12,222)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13,353&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">25,591&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(10,564)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15,027&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Licensing rights</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,766&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(2,931)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">835&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,743&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(2,791)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">952&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Marketing-related rights</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,362&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1,099)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">263&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,367&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1,041)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">326&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Research and development technology rights</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,298&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1,120)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">178&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,317&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1,065)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">252&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total finite-lived intangible assets</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32,001&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(17,372)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14,629&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32,018&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(15,461)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">16,557&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Indefinite-lived intangible assets:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">In-process research and development</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">30&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">30&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">30&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">30&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total other intangible assets</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32,031&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(17,372)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14,659&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32,048&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(15,461)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">16,587&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_ScheduleOfIntangibleAssetsTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of finite-lived and indefinite-lived identifiable intangible assets.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_ScheduleOfIntangibleAssetsTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfGoodwillTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of goodwill by reportable segment and in total which includes a rollforward schedule.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=121556970&amp;loc=d3e13816-109267<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 20<br> -Section 50<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=121556970&amp;loc=d3e13854-109267<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfGoodwillTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>40
<FILENAME>R30.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304047419960">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Financing arrangements (Tables)<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtDisclosureAbstract', window );"><strong>Debt Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfDebtInstrumentsTextBlock', window );">Schedule of borrowings</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Our borrowings consisted of the following (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:65.128%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.422%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1.25% &#8364;1,250 million notes due 2022 (1.25% 2022 euro Notes)</span></div></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,448&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,527&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.70% notes due 2022 (2.70% 2022 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">500&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">500&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.65% notes due 2022 (2.65% 2022 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,500&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,500&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.625% notes due 2022 (3.625% 2022 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">750&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">750&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">0.41% CHF700 million bonds due 2023 (0.41% 2023 Swiss franc Bonds)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">751&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">791&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.25% notes due 2023 (2.25% 2023 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">750&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">750&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.625% notes due 2024 (3.625% 2024 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,400&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,400&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1.90% notes due 2025 (1.90% 2025 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">500&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">500&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.125% notes due 2025 (3.125% 2025 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,000&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,000&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.00% &#8364;750 million notes due 2026 (2.00% 2026 euro Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">869&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">916&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.60% notes due 2026 (2.60% 2026 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.50% &#163;475 million notes due 2026 (5.50% 2026 pound sterling Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">640&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">649&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.20% notes due 2027 (2.20% 2027 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,750&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,750&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.20% notes due 2027 (3.20% 2027 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,000&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,000&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1.65% note due 2028 (1.65% 2028 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.00% &#163;700 million notes due 2029 (4.00% 2029 pound sterling Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">943&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">957&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.45% notes due 2030 (2.45% 2030 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.30% notes due 2031 (2.30% 2031 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.00% notes due 2032 (2.00% 2032 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.375% notes due 2037 (6.375% 2037 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">478&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">478&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.90% notes due 2038 (6.90% 2038 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">254&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">254&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.40% notes due 2039 (6.40% 2039 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">333&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">333&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.15% notes due 2040 (3.15% 2040 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,000&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,000&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.75% notes due 2040 (5.75% 2040 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">373&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">373&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.80% note due 2041 (2.80% 2041 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,150&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.95% notes due 2041 (4.95% 2041 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">600&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">600&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.15% notes due 2041 (5.15% 2041 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">729&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">729&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.65% notes due 2042 (5.65% 2042 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">415&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">415&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.375% notes due 2043 (5.375% 2043 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">185&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">185&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.40% notes due 2045 (4.40% 2045 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,250&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,250&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.563% notes due 2048 (4.563% 2048 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,415&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,415&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.375% notes due 2050 (3.375% 2050 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,250&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,250&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.663% notes due 2051 (4.663% 2051 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,541&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,541&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.00% notes due 2052 (3.00% 2052 Notes)</span></div></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,350&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.77% notes due 2053 (2.77% 2053 Notes)</span></div></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">940&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">940&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other notes due 2097</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">100&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">100&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Unamortized bond discounts, premiums and issuance costs, net</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1,221)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1,188)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Fair value adjustments</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">371&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">566&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total carrying value of debt</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">37,579&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32,986&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Less current portion</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(4,288)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(91)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total long-term debt</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33,291&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">32,895&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfDebtInstrumentsTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of long-debt instruments or arrangements, including identification, terms, features, collateral requirements and other information necessary to a fair presentation. These are debt arrangements that originally required repayment more than twelve months after issuance or greater than the normal operating cycle of the entity, if longer.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.22)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 3<br> -Subparagraph (SX 210.12-04(a))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e24072-122690<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 835<br> -SubTopic 30<br> -Section 45<br> -Paragraph 1A<br> -URI http://asc.fasb.org/extlink&amp;oid=124435984&amp;loc=d3e28541-108399<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 6<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=d3e21506-112644<br><br>Reference 5: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69B<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495735-112612<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 835<br> -SubTopic 30<br> -Section 45<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=124435984&amp;loc=d3e28551-108399<br><br>Reference 7: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69E<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495743-112612<br><br>Reference 8: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 7<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=d3e21521-112644<br><br>Reference 9: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=d3e21538-112644<br><br>Reference 10: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 470<br> -Section 50<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=123599511&amp;loc=d3e64711-112823<br><br>Reference 11: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 835<br> -SubTopic 30<br> -Section 55<br> -Paragraph 8<br> -URI http://asc.fasb.org/extlink&amp;oid=114775985&amp;loc=d3e28878-108400<br><br>Reference 12: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=d3e21475-112644<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfDebtInstrumentsTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>41
<FILENAME>R31.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304144815352">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Stockholders' equity (Tables)<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquityAbstract', window );"><strong>Equity [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_StockRepurchaseProgramTableTextBlock', window );">Summary of activity under our stock repurchase program</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Activity under our stock repurchase program, on a trade date basis, was as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:42.321%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.496%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.496%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.496%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.501%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Shares</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Dollars&#160;</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Shares</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Dollars</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">First quarter</span></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.7&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">865&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.3&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">933&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Second quarter</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.5&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,592&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.6&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">591&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Third quarter</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.6&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,069&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.0&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">752&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total stock repurchases</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14.8&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,526&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">9.9&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2,276&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock', window );">Components of accumulated other comprehensive income</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The components of Accumulated other comprehensive income (loss) (AOCI) were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:45.537%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.987%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.987%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.987%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.987%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.995%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Foreign<br/>currency<br/>translation</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Cash&#160;flow<br/>hedges</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Available-for-sale<br/>securities</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">AOCI</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of December 31, 2020</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(709)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(263)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(14)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(985)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency translation adjustments</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(39)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(39)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Unrealized gains</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">108&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">108&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Reclassification adjustments to income</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">133&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">133&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(51)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(51)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of March 31, 2021</span></div></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(748)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(73)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(13)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(833)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency translation adjustments</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">14&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Unrealized losses</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(31)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(31)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Reclassification adjustments to income</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(28)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(28)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">11&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">11&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of June 30, 2021</span></div></td><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(734)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(121)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(14)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(868)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency translation adjustments</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(35)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(35)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Unrealized gains (losses)</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">16&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(1)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Reclassification adjustments to income</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">109&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">109&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other</span></td><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(3)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(3)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income taxes</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(26)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(26)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Balance as of September 30, 2021</span></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(769)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(22)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(17)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(808)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock', window );">Reclassifications out of accumulated other comprehensive income</a></td>
<td class="text"><div style="margin-bottom:8pt;margin-top:7pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Reclassifications out of AOCI and into earnings, including related income tax expenses, were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:39.104%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:14.543%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:14.543%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:25.220%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended September 30,</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Components of AOCI</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Statements of Income locations</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash flow hedges:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contract (losses) gains</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(5)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">41&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Product sales</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contract (losses) gains</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(104)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">183&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income, net</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(109)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">224&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income before income taxes</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">23&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(49)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Provision for income taxes</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(86)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">175&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Available-for-sale securities:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net realized gains</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Provision for income taxes</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td></tr><tr style="height:15pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="9" style="background-color:#ffffff;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended September 30,</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Components of AOCI</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Statements of Income locations</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cash flow hedges:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contract (losses) gains</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(24)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">158&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Product sales</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contract (losses) gains</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(190)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">101&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income, net</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(214)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">259&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Income before income taxes</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">45&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(57)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Provision for income taxes</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(169)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">202&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Available-for-sale securities:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net realized gains</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other income, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(7)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Provision for income taxes</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">26&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Net income</span></td></tr></table></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_StockRepurchaseProgramTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Stock Repurchase Program [Table Text Block]</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_StockRepurchaseProgramTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EquityAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EquityAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of information about items reclassified out of accumulated other comprehensive income (loss).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of the components of accumulated other comprehensive income (loss).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 830<br> -SubTopic 30<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=6450520&amp;loc=d3e32583-110901<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 14A<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669686-108580<br><br>Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 830<br> -SubTopic 30<br> -Section 45<br> -Paragraph 20<br> -URI http://asc.fasb.org/extlink&amp;oid=118261656&amp;loc=d3e32211-110900<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>42
<FILENAME>R32.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304047419960">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Fair value measurement (Tables)<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueDisclosuresAbstract', window );"><strong>Fair Value Disclosures [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock', window );">Fair value of each major class of financial assets and liabilities measured at fair value on a recurring basis</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of each major class of the Company&#8217;s financial assets and liabilities measured at fair value on a recurring basis were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:40.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.788%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.788%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.788%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.796%"/><td style="width:0.1%"/></tr><tr style="height:12pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Quoted&#160;prices in<br/>active&#160;markets&#160;for<br/>identical assets<br/>(Level 1)</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Significant<br/>other&#160;observable<br/>inputs<br/>(Level 2)</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Significant<br/>unobservable<br/>inputs<br/>(Level 3)</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr style="height:12pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr style="height:12pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair value measurement as of September 30, 2021, using:</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Assets:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Available-for-sale securities:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">51&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">51&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury bills</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,900&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3,900&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Money market mutual funds</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">8,323&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">8,323&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other short-term interest-bearing securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Equity securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">608&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">257&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">865&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">127&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">127&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">119&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">119&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">29&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">29&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">12,882&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">276&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">257&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">13,415&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Liabilities:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">54&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">54&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">360&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">360&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">105&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">105&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Contingent consideration obligations</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">35&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">35&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total liabilities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">519&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">35&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">554&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:40.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.788%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.788%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.788%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:12.796%"/><td style="width:0.1%"/></tr><tr style="height:11pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Quoted&#160;prices in<br/>active&#160;markets&#160;for<br/>identical assets<br/>(Level 1)</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Significant<br/>other observable<br/>inputs<br/>(Level 2)</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="3" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Significant<br/>unobservable<br/>inputs<br/>(Level 3)</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr style="height:12pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr style="height:15pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair value measurement as of December 31, 2020, using:</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Total</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Assets:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Available-for-sale securities:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">130&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">130&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">U.S. Treasury bills</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,948&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,948&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Money market mutual funds</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,765&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4,765&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other short-term interest-bearing securities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Equity securities</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">477&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">477&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">28&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">28&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">255&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">255&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">66&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">66&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10,320&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">351&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">10,671&#160;</span></td><td style="background-color:#ffffff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:15pt"><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:3pt double #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:700;line-height:100%">Liabilities:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">237&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">237&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">318&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">318&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Contingent consideration obligations</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 25.75pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total liabilities</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">570&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">33&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">603&#160;</span></td><td style="background-color:#ffffff;border-bottom:3pt double #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FairValueDisclosuresAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FairValueDisclosuresAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of assets and liabilities, including [financial] instruments measured at fair value that are classified in stockholders' equity, if any, that are measured at fair value on a recurring basis. The disclosures contemplated herein include the fair value measurements at the reporting date by the level within the fair value hierarchy in which the fair value measurements in their entirety fall, segregating fair value measurements using quoted prices in active markets for identical assets (Level 1), significant other observable inputs (Level 2), and significant unobservable inputs (Level 3).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 820<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123874694&amp;loc=d3e19207-110258<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 820<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123874694&amp;loc=d3e19207-110258<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>43
<FILENAME>R33.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304048826104">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Derivative instruments (Tables)<br></strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th"><div>Sep. 30, 2021</div></th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract', window );"><strong>Derivative Instruments and Hedging Activities Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock', window );">Schedule of notional amounts and interest rates for cross-currency swaps</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The notional amounts and interest rates of our cross-currency swaps as of September 30, 2021, were as follows (notional amounts in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:29.894%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.420%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.426%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Foreign currency</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">U.S. dollars</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Hedged notes</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Notional amounts</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest rates</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Notional amounts</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest rates</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1.25% 2022 euro Notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8364;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,250&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1.3&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,388&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.2&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">0.41% 2023 Swiss franc Bonds</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">CHF</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">700&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">0.4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">704&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.4&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.00% 2026 euro Notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8364;</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">750&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">2.0&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">833&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">3.9&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.50% 2026 pound sterling Notes</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#163;</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">475&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">5.5&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">747&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6.0&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.00% 2029 pound sterling Notes</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#163;</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">700&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.0&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">1,111&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">4.5&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">%</span></td></tr></table></div><span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock', window );">Unrealized gain (loss) recognized in Other Comprehensive Income for our derivative instruments designated as cash flow hedges</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The unrealized gains and losses recognized in AOCI for our derivative instruments designated as cash flow hedges were as follows (in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:45.245%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.619%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.619%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.473%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.624%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended<br/>September 30,</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended<br/>September 30,</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivatives in cash flow hedging relationships</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">136&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(163)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">273&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(25)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(120)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">223&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(180)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(107)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 14.5pt;text-align:left;text-indent:-4.5pt;vertical-align:top"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total unrealized gains (losses)</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">16&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">60&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">93&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(132)</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock', window );">Derivatives in fair value hedging relationships</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The hedged liabilities and related cumulative-basis adjustments for fair value hedges of those liabilities were recorded in the Condensed Consolidated Balance Sheets as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:37.496%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:13.519%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:13.519%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:13.519%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:13.527%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Carrying amounts of hedged liabilities</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:5.2pt;font-weight:700;line-height:100%;position:relative;top:-2.8pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Cumulative amounts of fair value hedging adjustments related to the carrying amounts of the hedged liabilities</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:5.2pt;font-weight:700;line-height:100%;position:relative;top:-2.8pt;vertical-align:baseline">(2)</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated Balance Sheets locations</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Current portion of long-term debt</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">840&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">89&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">90&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">89&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Long-term debt</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,809&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,258&#160;</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">281&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">477&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-top:7pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">____________</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%"> &#160;&#160;&#160;&#160;Current portion of long-term debt includes $87 million and $89&#160;million of carrying value with discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively. Long-term debt includes $460 million and $525 million of carrying value with discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively.</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">(2)</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;Current portion of long-term debt includes $87 million and $89&#160;million of hedging adjustments on discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively. Long-term debt includes $360 million and $425 million of hedging adjustments on discontinued hedging relationships as of September 30, 2021 and December 31, 2020, respectively.</span></div><span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock', window );">Summary of amounts of income and expense line items</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The following tables summarize the amounts recorded in income and expense line items and the effects thereon from fair value and cash flow hedging, including discontinued hedging relationships (in millions):</span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.561%"><tr><td style="width:1.0%"/><td style="width:40.309%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:7.710%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:7.710%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.151%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:7.710%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.151%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.155%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended September 30, 2021</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Product sales</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other income, net</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest expense, net</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Product sales</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other income, net</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest expense, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total amounts recorded in income and (expense) line items presented in the Condensed Consolidated Statements of Income</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,320&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">73&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(296)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">18,026&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">97&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(862)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">The effects of cash flow and fair value hedging:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Losses on cash flow hedging relationships reclassified out of AOCI:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(5)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(24)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(104)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(190)</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Gains (losses) on fair value hedging relationships&#8212;interest rate swap agreements:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:11.25pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Hedged items</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">54&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">195&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives designated as hedging instruments</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(31)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(128)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span><br/></span></div><div style="margin-bottom:8pt;text-align:center"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.561%"><tr><td style="width:1.0%"/><td style="width:40.309%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:7.710%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.151%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.151%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:7.710%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:7.710%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.534%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.155%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Three months ended September 30, 2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Nine months ended September 30, 2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Product sales</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other income, net</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest expense, net</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Product sales</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Other income, net</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Interest expense, net</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total amounts recorded in income and (expense) line items presented in the Condensed Consolidated Statements of Income</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">6,104&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">55&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(302)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">17,906&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">69&#160;</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(944)</span></td><td style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">The effects of cash flow and fair value hedging:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Gains on cash flow hedging relationships reclassified out of AOCI:</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">41&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">158&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">183&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">101&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 7.75pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Gains (losses) on fair value hedging relationships&#8212;interest rate swap agreements:</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:11.25pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Hedged items</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:100%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">35&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">215&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 12.25pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Derivatives designated as hedging instruments</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(13)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">&#8212;&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">(150)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">__________</span></div><div style="margin-bottom:8pt;padding-left:13.5pt;text-align:justify;text-indent:-13.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:6.5pt;font-weight:400;line-height:120%;position:relative;top:-3.5pt;vertical-align:baseline">(1)</span><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">&#160;&#160;&#160;&#160;Gains on hedged items do not exactly offset losses on the related designated hedging instruments due to amortization of the cumulative amounts of fair value hedging adjustments included in the carrying amount of the hedged debt for discontinued hedging relationships and the recognition of gains on terminated hedges when the corresponding hedged item was paid down in the period.</span></div><span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock', window );">Fair values of derivatives included in the Condensed Consolidated Balance Sheets</a></td>
<td class="text"><div style="margin-bottom:8pt;text-align:justify;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The fair values of derivatives included in the Condensed Consolidated Balance Sheets were as follows (in millions):</span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:37.496%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:18.344%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.695%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:18.344%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.701%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivative assets</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivative liabilities</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">September 30, 2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Balance Sheets locations</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair&#160;values</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Balance Sheets locations</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair&#160;values</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivatives designated as hedging&#160;instruments:</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">127&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other&#160;noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">54&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">119&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other&#160;noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">360&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">29&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other&#160;noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">105&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total derivatives designated as hedging instruments</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">275&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">519&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div><span><br/></span></div><div style="margin-bottom:8pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:37.496%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:18.344%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.695%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:18.344%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.530%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.701%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:400;line-height:100%">&#160;</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivative assets</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivative liabilities</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">December 31, 2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Balance Sheets locations</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair&#160;values</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Condensed Consolidated<br/>Balance Sheets locations</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Fair&#160;values</span></td></tr><tr><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:8pt;font-weight:700;line-height:100%">Derivatives designated as hedging instruments:</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Foreign currency contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">28&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#ffffff;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">237&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Cross-currency swap contracts</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">255&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="2" style="background-color:#cceeff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">318&#160;</span></td><td style="background-color:#cceeff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Interest rate swap contracts</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt 2px 10pt;text-align:left;text-indent:-9pt;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Other current assets/ Other noncurrent assets</span></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">66&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:9pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Accrued liabilities/ Other noncurrent liabilities</span></div></td><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">15&#160;</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#cceeff;padding:2px 1pt;text-align:left;vertical-align:top"><div style="padding-left:15.75pt;text-indent:-9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">Total derivatives designated as hedging instruments</span></div></td><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">349&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td colspan="3" style="background-color:#cceeff;padding:0 1pt"/><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">$</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:100%">570&#160;</span></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Schedule of Notional Amounts and Interest Rates for Cross-Currency Swaps</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of gain (loss) on derivative and nonderivative instruments designated and qualifying as cash flow hedge recorded in accumulated other comprehensive income (AOCI) and reclassified into earnings.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4C<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL5624171-113959<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of the location and fair value amounts of derivative instruments (and nonderivative instruments that are designated and qualify as hedging instruments) reported in the statement of financial position.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4B<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL5624163-113959<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure of derivative instruments (including nonderivative instruments that are designated and qualify as hedging instruments) of (a) the location and amount of gains and losses reported in the statement of financial performance and (b) the location and fair value amounts of the instruments reported in the statement of financial position.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4A<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL5618551-113959<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Tabular disclosure for fair value hedging instruments of (a) the location and amount of gains and losses reported in the statement of financial performance and (b) the location and fair value amounts of the instruments reported in the statement of financial position.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4C<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL5624171-113959<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:textBlockItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>44
<FILENAME>R34.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304047227592">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Summary of significant accounting policies (Details)<br> $ in Billions</strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
<th class="th" colspan="1"></th>
</tr>
<tr>
<th class="th">
<div>Sep. 30, 2021 </div>
<div>USD ($) </div>
<div>segment</div>
</th>
<th class="th">
<div>Dec. 31, 2020 </div>
<div>USD ($)</div>
</th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AccountingPoliciesAbstract', window );"><strong>Accounting Policies [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NumberOfOperatingSegments', window );">Number of operating segments | segment</a></td>
<td class="nump">1<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment', window );">Accumulated depreciation and amortization on property, plant and equipment | $</a></td>
<td class="nump">$ 9.2<span></span>
</td>
<td class="nump">$ 9.0<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccountingPoliciesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccountingPoliciesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 360<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=6391035&amp;loc=d3e2868-110229<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.14)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NumberOfOperatingSegments">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Number of operating segments. An operating segment is a component of an enterprise: (a) that engages in business activities from which it may earn revenues and incur expenses (including revenues and expenses relating to transactions with other components of the same enterprise), (b) whose operating results are regularly reviewed by the enterprise's chief operating decision maker to make decisions about resources to be allocated to the segment and assess its performance, and (c) for which discrete financial information is available. An operating segment may engage in business activities for which it has yet to earn revenues, for example, start-up operations may be operating segments before earning revenues.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 18<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8672-108599<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NumberOfOperatingSegments</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:integerItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>45
<FILENAME>R35.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304055287656">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Business Combinations and Asset Acquisitions (Details) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th" colspan="1"></th>
<th class="th" colspan="2">3 Months Ended</th>
<th class="th" colspan="2">9 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Apr. 16, 2021</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_BusinessAcquisitionLineItems', window );"><strong>Business Acquisition [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired', window );">Payments to Acquire Businesses, Net of Cash Acquired</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 1,639<span></span>
</td>
<td class="nump">$ 0<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff', window );">Acquired in-process research and development</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 0<span></span>
</td>
<td class="nump">$ 0<span></span>
</td>
<td class="nump">$ 1,505<span></span>
</td>
<td class="nump">$ 0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_BusinessAcquisitionAxis=amgn_FivePrimeTherapeuticsIncMember', window );">Five Prime Therapeutics, Inc.</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_BusinessAcquisitionLineItems', window );"><strong>Business Acquisition [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired', window );">Payments to Acquire Businesses, Net of Cash Acquired</a></td>
<td class="nump">$ 1,600<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff', window );">Acquired in-process research and development</a></td>
<td class="nump">1,500<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther', window );">Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Liabilities, Other</a></td>
<td class="nump">47<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets', window );">Business Combination Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Assets</a></td>
<td class="nump">$ 177<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_BusinessAcquisitionLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_BusinessAcquisitionLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of other liabilities due within one year or within the normal operating cycle, if longer, assumed at the acquisition date.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 805<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123413009&amp;loc=d3e4845-128472<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of deferred tax asset attributable to deductible temporary differences and carryforwards acquired at the acquisition date.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 805<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123413009&amp;loc=d3e4845-128472<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The cash outflow associated with the acquisition of a business, net of the cash acquired from the purchase.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 13<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3213-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The amount of the write-off for research and development assets that were acquired in a transaction other than a business combination.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16265-109275<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_BusinessAcquisitionAxis=amgn_FivePrimeTherapeuticsIncMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_BusinessAcquisitionAxis=amgn_FivePrimeTherapeuticsIncMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>46
<FILENAME>R36.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304142879800">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Revenues (Details)<br> $ in Millions</strong></div></th>
<th class="th" colspan="2">3 Months Ended</th>
<th class="th" colspan="2">9 Months Ended</th>
</tr>
<tr>
<th class="th">
<div>Sep. 30, 2021 </div>
<div>USD ($)</div>
</th>
<th class="th">
<div>Sep. 30, 2020 </div>
<div>USD ($)</div>
</th>
<th class="th">
<div>Sep. 30, 2021 </div>
<div>USD ($) </div>
<div>segment</div>
</th>
<th class="th">
<div>Sep. 30, 2020 </div>
<div>USD ($)</div>
</th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerAbstract', window );"><strong>Revenue from Contract with Customer [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NumberOfOperatingSegments', window );">Number of operating segments | segment</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">$ 6,706<span></span>
</td>
<td class="nump">$ 6,423<span></span>
</td>
<td class="nump">$ 19,133<span></span>
</td>
<td class="nump">$ 18,790<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=us-gaap_ProductMember', window );">Product sales [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">6,320<span></span>
</td>
<td class="nump">6,104<span></span>
</td>
<td class="nump">18,026<span></span>
</td>
<td class="nump">17,906<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=us-gaap_ProductMember', window );">Product sales [Member] | US [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">4,558<span></span>
</td>
<td class="nump">4,618<span></span>
</td>
<td class="nump">12,835<span></span>
</td>
<td class="nump">13,325<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=us-gaap_ProductMember', window );">Product sales [Member] | ROW [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">1,762<span></span>
</td>
<td class="nump">1,486<span></span>
</td>
<td class="nump">5,191<span></span>
</td>
<td class="nump">4,581<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_EnbrelMember', window );">Enbrel&#174; (etanercept) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">1,289<span></span>
</td>
<td class="nump">1,325<span></span>
</td>
<td class="nump">3,357<span></span>
</td>
<td class="nump">3,724<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_EnbrelMember', window );">Enbrel&#174; (etanercept) [Member] | US [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">1,263<span></span>
</td>
<td class="nump">1,289<span></span>
</td>
<td class="nump">3,270<span></span>
</td>
<td class="nump">3,619<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_EnbrelMember', window );">Enbrel&#174; (etanercept) [Member] | ROW [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">26<span></span>
</td>
<td class="nump">36<span></span>
</td>
<td class="nump">87<span></span>
</td>
<td class="nump">105<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_ProliaMember', window );">Prolia&#174; (denosumab) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">803<span></span>
</td>
<td class="nump">701<span></span>
</td>
<td class="nump">2,375<span></span>
</td>
<td class="nump">2,014<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_ProliaMember', window );">Prolia&#174; (denosumab) [Member] | US [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">530<span></span>
</td>
<td class="nump">478<span></span>
</td>
<td class="nump">1,569<span></span>
</td>
<td class="nump">1,341<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_ProliaMember', window );">Prolia&#174; (denosumab) [Member] | ROW [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">273<span></span>
</td>
<td class="nump">223<span></span>
</td>
<td class="nump">806<span></span>
</td>
<td class="nump">673<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_OtezlaMember', window );">Otezla (apremilast) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">609<span></span>
</td>
<td class="nump">538<span></span>
</td>
<td class="nump">1,619<span></span>
</td>
<td class="nump">1,578<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_OtezlaMember', window );">Otezla (apremilast) [Member] | US [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">495<span></span>
</td>
<td class="nump">439<span></span>
</td>
<td class="nump">1,284<span></span>
</td>
<td class="nump">1,280<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_OtezlaMember', window );">Otezla (apremilast) [Member] | ROW [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">114<span></span>
</td>
<td class="nump">99<span></span>
</td>
<td class="nump">335<span></span>
</td>
<td class="nump">298<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_XgevaMember', window );">XGEVA&#174; (denosumab) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">517<span></span>
</td>
<td class="nump">481<span></span>
</td>
<td class="nump">1,473<span></span>
</td>
<td class="nump">1,397<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_XgevaMember', window );">XGEVA&#174; (denosumab) [Member] | US [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">372<span></span>
</td>
<td class="nump">363<span></span>
</td>
<td class="nump">1,061<span></span>
</td>
<td class="nump">1,036<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_XgevaMember', window );">XGEVA&#174; (denosumab) [Member] | ROW [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">145<span></span>
</td>
<td class="nump">118<span></span>
</td>
<td class="nump">412<span></span>
</td>
<td class="nump">361<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_NeulastaMember', window );">Neulasta&#174; (pegfilgrastim) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">415<span></span>
</td>
<td class="nump">555<span></span>
</td>
<td class="nump">1,383<span></span>
</td>
<td class="nump">1,757<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_NeulastaMember', window );">Neulasta&#174; (pegfilgrastim) [Member] | US [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">360<span></span>
</td>
<td class="nump">484<span></span>
</td>
<td class="nump">1,215<span></span>
</td>
<td class="nump">1,538<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_NeulastaMember', window );">Neulasta&#174; (pegfilgrastim) [Member] | ROW [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">55<span></span>
</td>
<td class="nump">71<span></span>
</td>
<td class="nump">168<span></span>
</td>
<td class="nump">219<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_AranespMember', window );">Aranesp&#174; (darbepoetin alfa) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">396<span></span>
</td>
<td class="nump">384<span></span>
</td>
<td class="nump">1,118<span></span>
</td>
<td class="nump">1,193<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_AranespMember', window );">Aranesp&#174; (darbepoetin alfa) [Member] | US [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">149<span></span>
</td>
<td class="nump">158<span></span>
</td>
<td class="nump">409<span></span>
</td>
<td class="nump">489<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_AranespMember', window );">Aranesp&#174; (darbepoetin alfa) [Member] | ROW [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">247<span></span>
</td>
<td class="nump">226<span></span>
</td>
<td class="nump">709<span></span>
</td>
<td class="nump">704<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_RepathaevolocumabMember', window );">Repatha (evolocumab) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">272<span></span>
</td>
<td class="nump">205<span></span>
</td>
<td class="nump">844<span></span>
</td>
<td class="nump">634<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_RepathaevolocumabMember', window );">Repatha (evolocumab) [Member] | US [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">139<span></span>
</td>
<td class="nump">92<span></span>
</td>
<td class="nump">421<span></span>
</td>
<td class="nump">331<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_RepathaevolocumabMember', window );">Repatha (evolocumab) [Member] | ROW [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">133<span></span>
</td>
<td class="nump">113<span></span>
</td>
<td class="nump">423<span></span>
</td>
<td class="nump">303<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_KyprolisMember', window );">KYPROLIS&#174; (carfilzomib) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">293<span></span>
</td>
<td class="nump">260<span></span>
</td>
<td class="nump">824<span></span>
</td>
<td class="nump">793<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_KyprolisMember', window );">KYPROLIS&#174; (carfilzomib) [Member] | US [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">198<span></span>
</td>
<td class="nump">173<span></span>
</td>
<td class="nump">547<span></span>
</td>
<td class="nump">527<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_KyprolisMember', window );">KYPROLIS&#174; (carfilzomib) [Member] | ROW [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">95<span></span>
</td>
<td class="nump">87<span></span>
</td>
<td class="nump">277<span></span>
</td>
<td class="nump">266<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_OtherProductsMember', window );">Other products [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">1,726<span></span>
</td>
<td class="nump">1,655<span></span>
</td>
<td class="nump">5,033<span></span>
</td>
<td class="nump">4,816<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_OtherProductsMember', window );">Other products [Member] | US [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">1,052<span></span>
</td>
<td class="nump">1,142<span></span>
</td>
<td class="nump">3,059<span></span>
</td>
<td class="nump">3,164<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=amgn_OtherProductsMember', window );">Other products [Member] | ROW [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">674<span></span>
</td>
<td class="nump">513<span></span>
</td>
<td class="nump">1,974<span></span>
</td>
<td class="nump">1,652<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=us-gaap_ProductAndServiceOtherMember', window );">Other revenues [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems', window );"><strong>Revenue from External Customer [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">$ 386<span></span>
</td>
<td class="nump">$ 319<span></span>
</td>
<td class="nump">$ 1,107<span></span>
</td>
<td class="nump">$ 884<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NumberOfOperatingSegments">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Number of operating segments. An operating segment is a component of an enterprise: (a) that engages in business activities from which it may earn revenues and incur expenses (including revenues and expenses relating to transactions with other components of the same enterprise), (b) whose operating results are regularly reviewed by the enterprise's chief operating decision maker to make decisions about resources to be allocated to the segment and assess its performance, and (c) for which discrete financial information is available. An operating segment may engage in business activities for which it has yet to earn revenues, for example, start-up operations may be operating segments before earning revenues.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 18<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8672-108599<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NumberOfOperatingSegments</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:integerItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_RevenueFromContractWithCustomerAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_RevenueFromContractWithCustomerAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8906-108599<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 40<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e9031-108599<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 41<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e9038-108599<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130543-203045<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 42<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e9054-108599<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 5<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130545-203045<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 924<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB Topic 11.L)<br> -URI http://asc.fasb.org/extlink&amp;oid=6472922&amp;loc=d3e499488-122856<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=us-gaap_ProductMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=us-gaap_ProductMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_StatementGeographicalAxis=country_US">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_StatementGeographicalAxis=country_US</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_StatementGeographicalAxis=us-gaap_NonUsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_StatementGeographicalAxis=us-gaap_NonUsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=amgn_EnbrelMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=amgn_EnbrelMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=amgn_ProliaMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=amgn_ProliaMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=amgn_OtezlaMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=amgn_OtezlaMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=amgn_XgevaMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=amgn_XgevaMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=amgn_NeulastaMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=amgn_NeulastaMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=amgn_AranespMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=amgn_AranespMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=amgn_RepathaevolocumabMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=amgn_RepathaevolocumabMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=amgn_KyprolisMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=amgn_KyprolisMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=amgn_OtherProductsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=amgn_OtherProductsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=us-gaap_ProductAndServiceOtherMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=us-gaap_ProductAndServiceOtherMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>47
<FILENAME>R37.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304142584296">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Income taxes (Details) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th" colspan="2">3 Months Ended</th>
<th class="th" colspan="2">9 Months Ended</th>
<th class="th" colspan="1"></th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>May 31, 2021</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncomeTaxDisclosureAbstract', window );"><strong>Income Tax Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EffectiveIncomeTaxRateContinuingOperations', window );">Effective income tax rate</a></td>
<td class="nump">12.60%<span></span>
</td>
<td class="nump">8.40%<span></span>
</td>
<td class="nump">12.60%<span></span>
</td>
<td class="nump">9.70%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions', window );">Increase in unrecognized tax benefits resulting from tax positions taken during the current period</a></td>
<td class="nump">$ 70<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 180<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_ProposedAdditionalIncomeTax', window );">Proposed additional income tax</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 3,600<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_RepatriationTaxOnProposedAdditionalTax', window );">Repatriation tax on proposed additional tax</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 900<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_ProposedAdditionalIncomeTax">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Proposed additional income tax</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_ProposedAdditionalIncomeTax</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_RepatriationTaxOnProposedAdditionalTax">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Repatriation tax on proposed additional tax</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_RepatriationTaxOnProposedAdditionalTax</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EffectiveIncomeTaxRateContinuingOperations">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Percentage of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section 50<br> -Paragraph 12<br> -URI http://asc.fasb.org/extlink&amp;oid=121826272&amp;loc=d3e32687-109319<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EffectiveIncomeTaxRateContinuingOperations</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of increase in unrecognized tax benefits resulting from tax positions that have been or will be taken in current period tax return.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section 50<br> -Paragraph 15A<br> -Subparagraph (a)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=121826272&amp;loc=SL6600010-109319<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>48
<FILENAME>R38.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051373400">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Earnings per share (Details) - USD ($)<br> $ / shares in Units, shares in Millions, $ in Millions</strong></div></th>
<th class="th" colspan="6">3 Months Ended</th>
<th class="th" colspan="2">9 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Jun. 30, 2021</div></th>
<th class="th"><div>Mar. 31, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Jun. 30, 2020</div></th>
<th class="th"><div>Mar. 31, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLossAbstract', window );"><strong>Income (Numerator):</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income for basic and diluted EPS</a></td>
<td class="nump">$ 1,884<span></span>
</td>
<td class="nump">$ 464<span></span>
</td>
<td class="nump">$ 1,646<span></span>
</td>
<td class="nump">$ 2,021<span></span>
</td>
<td class="nump">$ 1,803<span></span>
</td>
<td class="nump">$ 1,825<span></span>
</td>
<td class="nump">$ 3,994<span></span>
</td>
<td class="nump">$ 5,649<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract', window );"><strong>Shares (Denominator):</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic', window );">Weighted-average shares for basic EPS (in shares)</a></td>
<td class="nump">567<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">585<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">572<span></span>
</td>
<td class="nump">588<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment', window );">Effect of dilutive securities (in shares)</a></td>
<td class="nump">3<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">4<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">4<span></span>
</td>
<td class="nump">4<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding', window );">Weighted-average shares for diluted EPS (in shares)</a></td>
<td class="nump">570<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">589<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">576<span></span>
</td>
<td class="nump">592<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EarningsPerShareBasic', window );">Basic EPS (in usd per share)</a></td>
<td class="nump">$ 3.32<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 3.45<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 6.98<span></span>
</td>
<td class="nump">$ 9.61<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EarningsPerShareDiluted', window );">Diluted EPS (in usd per share)</a></td>
<td class="nump">$ 3.31<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 3.43<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 6.93<span></span>
</td>
<td class="nump">$ 9.54<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EarningsPerShareBasic">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The amount of net income (loss) for the period per each share of common stock or unit outstanding during the reporting period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (e)(4)<br> -URI http://asc.fasb.org/extlink&amp;oid=123482062&amp;loc=SL123482106-238011<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22583-107794<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=d3e1448-109256<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22595-107794<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 7<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=d3e1337-109256<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123482062&amp;loc=SL123482106-238011<br><br>Reference 9: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 55<br> -Paragraph 52<br> -URI http://asc.fasb.org/extlink&amp;oid=125512782&amp;loc=d3e4984-109258<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(23))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 55<br> -Paragraph 15<br> -URI http://asc.fasb.org/extlink&amp;oid=125512782&amp;loc=d3e3842-109258<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 7<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22644-107794<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124432515&amp;loc=d3e3550-109257<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(25))<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=d3e1252-109256<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=SL5780133-109256<br><br>Reference 17: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(27))<br> -URI http://asc.fasb.org/extlink&amp;oid=120399700&amp;loc=SL114874048-224260<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EarningsPerShareBasic</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EarningsPerShareDiluted">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The amount of net income (loss) for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 55<br> -Paragraph 52<br> -URI http://asc.fasb.org/extlink&amp;oid=125512782&amp;loc=d3e4984-109258<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 7<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22644-107794<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 55<br> -Paragraph 15<br> -URI http://asc.fasb.org/extlink&amp;oid=125512782&amp;loc=d3e3842-109258<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=d3e1252-109256<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22595-107794<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22583-107794<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=SL5780133-109256<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123482062&amp;loc=SL123482106-238011<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(27))<br> -URI http://asc.fasb.org/extlink&amp;oid=120399700&amp;loc=SL114874048-224260<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124432515&amp;loc=d3e3550-109257<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(23))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 7<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=d3e1337-109256<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (e)(4)<br> -URI http://asc.fasb.org/extlink&amp;oid=123482062&amp;loc=SL123482106-238011<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(25))<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EarningsPerShareDiluted</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetIncomeLoss">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(22))<br> -URI http://asc.fasb.org/extlink&amp;oid=120399700&amp;loc=SL114874048-224260<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22595-107794<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(18))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123482062&amp;loc=SL123482106-238011<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 50<br> -Paragraph 6<br> -URI http://asc.fasb.org/extlink&amp;oid=124431353&amp;loc=SL124452729-227067<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 8: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(20))<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br><br>Reference 9: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22499-107794<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 9<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22663-107794<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 17: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123596393&amp;loc=d3e14064-108612<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22583-107794<br><br>Reference 20: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 21: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=SL5780133-109256<br><br>Reference 22: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br><br>Reference 23: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22658-107794<br><br>Reference 24: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1A<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669619-108580<br><br>Reference 25: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 31<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8924-108599<br><br>Reference 26: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 27: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 28: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 205<br> -SubTopic 20<br> -Section 50<br> -Paragraph 7<br> -URI http://asc.fasb.org/extlink&amp;oid=109222650&amp;loc=SL51721683-107760<br><br>Reference 29: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1B<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669625-108580<br><br>Reference 30: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 31: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 32: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(B))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 33: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 34: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8906-108599<br><br>Reference 35: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetIncomeLoss</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetIncomeLossAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetIncomeLossAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The sum of dilutive potential common shares or units used in the calculation of the diluted per-share or per-unit computation.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124432515&amp;loc=d3e3550-109257<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The average number of shares or units issued and outstanding that are used in calculating diluted EPS or earnings per unit (EPU), determined based on the timing of issuance of shares or units in the period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124432515&amp;loc=d3e3550-109257<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 16<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=d3e1505-109256<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Number of [basic] shares or units, after adjustment for contingently issuable shares or units and other shares or units not deemed outstanding, determined by relating the portion of time within a reporting period that common shares or units have been outstanding to the total time in that period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124432515&amp;loc=d3e3550-109257<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=d3e1448-109256<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_WeightedAverageNumberOfSharesOutstandingBasic</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>49
<FILENAME>R39.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051394392">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Collaborations (Details) - Kyowa Kirin Co. Ltd.<br> $ in Millions</strong></div></th>
<th class="th" colspan="1">3 Months Ended</th>
</tr>
<tr><th class="th">
<div>Sep. 30, 2021 </div>
<div>USD ($)</div>
</th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems', window );"><strong>Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_UpFrontPayment', window );">Up-front payment</a></td>
<td class="nump">$ 400<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments', window );">Revenue Recognition, Milestone Method, Potential Future Milestone payments</a></td>
<td class="nump">$ 850<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Revenue Recognition, Milestone Method, Potential Future Milestone Payments</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_UpFrontPayment">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Up-front payment</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_UpFrontPayment</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_TypeOfArrangementAxis=amgn_KyowaKirinCoLtdMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_TypeOfArrangementAxis=amgn_KyowaKirinCoLtdMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>50
<FILENAME>R40.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304055098536">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Investments (Details) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems', window );"><strong>Debt Securities, Available-for-sale [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis', window );">Amortized cost</a></td>
<td class="nump">$ 12,275<span></span>
</td>
<td class="nump">$ 9,844<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax', window );">Gross unrealized gains</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">1<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax', window );">Gross unrealized losses</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Fair values</a></td>
<td class="nump">12,275<span></span>
</td>
<td class="nump">9,845<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_USTreasurySecuritiesMember', window );">U.S. Treasury notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems', window );"><strong>Debt Securities, Available-for-sale [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis', window );">Amortized cost</a></td>
<td class="nump">51<span></span>
</td>
<td class="nump">129<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax', window );">Gross unrealized gains</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">1<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax', window );">Gross unrealized losses</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Fair values</a></td>
<td class="nump">51<span></span>
</td>
<td class="nump">130<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_USTreasuryBillSecuritiesMember', window );">U.S. Treasury bills [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems', window );"><strong>Debt Securities, Available-for-sale [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis', window );">Amortized cost</a></td>
<td class="nump">3,900<span></span>
</td>
<td class="nump">4,948<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax', window );">Gross unrealized gains</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax', window );">Gross unrealized losses</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Fair values</a></td>
<td class="nump">3,900<span></span>
</td>
<td class="nump">4,948<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_MoneyMarketFundsMember', window );">Money market mutual funds [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems', window );"><strong>Debt Securities, Available-for-sale [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis', window );">Amortized cost</a></td>
<td class="nump">8,323<span></span>
</td>
<td class="nump">4,765<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax', window );">Gross unrealized gains</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax', window );">Gross unrealized losses</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Fair values</a></td>
<td class="nump">8,323<span></span>
</td>
<td class="nump">4,765<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=amgn_OtherShortTermInterestBearingSecuritiesMember', window );">Other short-term interest-bearing securities [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems', window );"><strong>Debt Securities, Available-for-sale [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis', window );">Amortized cost</a></td>
<td class="nump">1<span></span>
</td>
<td class="nump">2<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax', window );">Gross unrealized gains</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax', window );">Gross unrealized losses</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Fair values</a></td>
<td class="nump">$ 1<span></span>
</td>
<td class="nump">$ 2<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount, before tax, of unrealized gain in accumulated other comprehensive income (AOCI) on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123581744&amp;loc=d3e27161-111563<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount, before tax, of unrealized loss in accumulated other comprehensive income (AOCI) on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123581744&amp;loc=d3e27161-111563<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amortized cost of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123581744&amp;loc=d3e27161-111563<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 326<br> -SubTopic 30<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=124258926&amp;loc=SL82898722-210454<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03(6))<br> -URI http://asc.fasb.org/extlink&amp;oid=120398452&amp;loc=d3e534808-122878<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 326<br> -SubTopic 30<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=124258926&amp;loc=SL82898722-210454<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124260329&amp;loc=d3e26610-111562<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (aa)<br> -URI http://asc.fasb.org/extlink&amp;oid=123581744&amp;loc=d3e27161-111563<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AvailableForSaleSecuritiesDebtSecurities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FinancialInstrumentAxis=us-gaap_USTreasurySecuritiesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FinancialInstrumentAxis=us-gaap_USTreasurySecuritiesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FinancialInstrumentAxis=us-gaap_USTreasuryBillSecuritiesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FinancialInstrumentAxis=us-gaap_USTreasuryBillSecuritiesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FinancialInstrumentAxis=us-gaap_MoneyMarketFundsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FinancialInstrumentAxis=us-gaap_MoneyMarketFundsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FinancialInstrumentAxis=amgn_OtherShortTermInterestBearingSecuritiesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FinancialInstrumentAxis=amgn_OtherShortTermInterestBearingSecuritiesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>51
<FILENAME>R41.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304048439160">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Investments (Fair Values by Classification) (Details) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract', window );"><strong>Fair values of available-for-sale investments by classification in the Consolidated Balance Sheets</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent', window );">Marketable securities</a></td>
<td class="nump">$ 952<span></span>
</td>
<td class="nump">$ 4,381<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Total interest-bearing securities</a></td>
<td class="nump">12,275<span></span>
</td>
<td class="nump">9,845<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=amgn_AvailableForSalesInvestmentsMember', window );">Available-for-sale investments [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract', window );"><strong>Fair values of available-for-sale investments by classification in the Consolidated Balance Sheets</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CashAndCashEquivalentsFairValueDisclosure', window );">Cash and cash equivalents</a></td>
<td class="nump">11,323<span></span>
</td>
<td class="nump">5,464<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent', window );">Marketable securities</a></td>
<td class="nump">952<span></span>
</td>
<td class="nump">4,381<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Total interest-bearing securities</a></td>
<td class="nump">$ 12,275<span></span>
</td>
<td class="nump">$ 9,845<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fair values of available-for-sale investments by classification in the Consolidated Balance Sheets.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03(6))<br> -URI http://asc.fasb.org/extlink&amp;oid=120398452&amp;loc=d3e534808-122878<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 326<br> -SubTopic 30<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=124258926&amp;loc=SL82898722-210454<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124260329&amp;loc=d3e26610-111562<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (aa)<br> -URI http://asc.fasb.org/extlink&amp;oid=123581744&amp;loc=d3e27161-111563<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AvailableForSaleSecuritiesDebtSecurities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), classified as current.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 326<br> -SubTopic 30<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=124258926&amp;loc=SL82898722-210454<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 45<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=124260329&amp;loc=d3e26626-111562<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CashAndCashEquivalentsFairValueDisclosure">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fair value portion of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CashAndCashEquivalentsFairValueDisclosure</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FinancialInstrumentAxis=amgn_AvailableForSalesInvestmentsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FinancialInstrumentAxis=amgn_AvailableForSalesInvestmentsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>52
<FILENAME>R42.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304045880920">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Investments (Available-for-sale Investments) (Details Textual) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract', window );"><strong>Investments, Debt and Equity Securities [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_Cash', window );">Cash</a></td>
<td class="nump">$ 646<span></span>
</td>
<td class="nump">$ 802<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_Cash">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Excludes cash and cash equivalents within disposal group and discontinued operation.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 946<br> -SubTopic 210<br> -Section 45<br> -Paragraph 20<br> -URI http://asc.fasb.org/extlink&amp;oid=118262064&amp;loc=SL116631418-115840<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.1)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 946<br> -SubTopic 210<br> -Section 45<br> -Paragraph 21<br> -URI http://asc.fasb.org/extlink&amp;oid=118262064&amp;loc=SL116631419-115840<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_Cash</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>53
<FILENAME>R43.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304047292776">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Investments (Fair Values by Contractual Maturity) (Details) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract', window );"><strong>Investments, Debt and Equity Securities [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue', window );">Maturing in one year or less</a></td>
<td class="nump">$ 12,275<span></span>
</td>
<td class="nump">$ 9,795<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue', window );">Maturing after one year through three years</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">50<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Total interest-bearing securities</a></td>
<td class="nump">$ 12,275<span></span>
</td>
<td class="nump">$ 9,845<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Available-For Sale Securities, Debt Maturities, After One Through Three Years, Fair Value</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fair value of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), with single maturity date and allocated without single maturity date, maturing in next fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 320<br> -Section 50<br> -Paragraph 3A<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123599081&amp;loc=SL120269850-112803<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123581744&amp;loc=d3e27198-111563<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=123581744&amp;loc=d3e27161-111563<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03(6))<br> -URI http://asc.fasb.org/extlink&amp;oid=120398452&amp;loc=d3e534808-122878<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 326<br> -SubTopic 30<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=124258926&amp;loc=SL82898722-210454<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124260329&amp;loc=d3e26610-111562<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (aa)<br> -URI http://asc.fasb.org/extlink&amp;oid=123581744&amp;loc=d3e27161-111563<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AvailableForSaleSecuritiesDebtSecurities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>54
<FILENAME>R44.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304144634120">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Investments (Equity Securities) (Details Textual) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th" colspan="2">3 Months Ended</th>
<th class="th" colspan="2">9 Months Ended</th>
<th class="th" colspan="1"></th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems', window );"><strong>Debt Securities, Available-for-sale [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquitySecuritiesFvNi', window );">Equity securities</a></td>
<td class="nump">$ 865<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 865<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 477<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss', window );">Equity Securities, FV-NI, Unrealized Gain (Loss)</a></td>
<td class="nump">135<span></span>
</td>
<td class="nump">$ 60<span></span>
</td>
<td class="nump">104<span></span>
</td>
<td class="nump">$ 65<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount', window );">Equity securities without readily determinable fair value</a></td>
<td class="nump">255<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">255<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">203<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount', window );">Equity Securities without Readily Determinable Fair Value, Upward Price Adjustment, Annual Amount</a></td>
<td class="nump">94<span></span>
</td>
<td class="nump">$ 12<span></span>
</td>
<td class="nump">129<span></span>
</td>
<td class="nump">$ 20<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel1Member', window );">Fair Value, Inputs, Level 1 [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems', window );"><strong>Debt Securities, Available-for-sale [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquitySecuritiesFvNi', window );">Equity securities</a></td>
<td class="nump">$ 608<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 608<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 477<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EquitySecuritiesFvNi">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of investment in equity security measured at fair value with change in fair value recognized in net income (FV-NI), classified as current.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1A<br> -URI http://asc.fasb.org/extlink&amp;oid=123594786&amp;loc=SL75136599-209740<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EquitySecuritiesFvNi</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of unrealized gain (loss) on investment in equity security measured at fair value with change in fair value recognized in net income (FV-NI).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(3)(d))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 321<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=123583765&amp;loc=SL75117546-209714<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of investment in equity security without readily determinable fair value.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 321<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123583765&amp;loc=SL75117539-209714<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of gain from upward price adjustment on investment in equity security without readily determinable fair value.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 321<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123583765&amp;loc=SL75117539-209714<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel1Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel1Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>55
<FILENAME>R45.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051830520">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Investments Investments (Limited Partnership Investments) (Details) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th" colspan="1"></th>
<th class="th" colspan="2">3 Months Ended</th>
<th class="th" colspan="2">9 Months Ended</th>
<th class="th" colspan="1"></th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems', window );"><strong>Net Investment Income [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_PaymentsToAcquireEquityMethodInvestments', window );">Payments to Acquire Equity Method Investments</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 154<span></span>
</td>
<td class="nump">$ 3,154<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InvestmentTypeAxis=srt_PartnershipInterestMember', window );">Limited Partnership [Member] | Fair Value Measured at Net Asset Value Per Share [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems', window );"><strong>Net Investment Income [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AlternativeInvestment', window );">Alternative investments</a></td>
<td class="nump">$ 556<span></span>
</td>
<td class="nump">$ 556<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">556<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 496<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_AlternativeInvestmentNetGainLoss', window );">Net gains (losses) from limited partnership investments</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(43)<span></span>
</td>
<td class="nump">$ 63<span></span>
</td>
<td class="nump">122<span></span>
</td>
<td class="nump">$ 73<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_BusinessAcquisitionAxis=amgn_BeiGeneMember', window );">BeiGene [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems', window );"><strong>Net Investment Income [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquityMethodInvestments', window );">Carrying value of equity method investment</a></td>
<td class="nump">$ 2,700<span></span>
</td>
<td class="nump">$ 2,700<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 2,700<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquityMethodInvestmentOwnershipPercentage', window );">Ownership percentage</a></td>
<td class="nump">20.30%<span></span>
</td>
<td class="nump">20.30%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">20.30%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquityMethodInvestmentQuotedMarketValue', window );">Equity Method Investments,Quoted Market Price</a></td>
<td class="nump">$ 6,900<span></span>
</td>
<td class="nump">$ 6,900<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 6,900<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_EquityMethodInvestmentChangeInCarryingValue', window );">Equity method investment, change in carrying value</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">50<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">50<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncomeLossFromEquityMethodInvestments', window );">Income (Loss) from Equity Method Investments</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(98)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(181)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity', window );">Equity Method Investment, Amortization of Difference Between Carrying Amount and Underlying Equity</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">44<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">128<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_EquityMethodInvestmentChangeInCarryingValueOther', window );">Equity Method Investment, Change In Carrying Value, Other</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">18<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">56<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_BusinessAcquisitionAxis=amgn_NeumoraTherapeuticsIncMember', window );">Neumora Therapeutics, Inc. [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems', window );"><strong>Net Investment Income [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquityMethodInvestmentAggregateCost', window );">Equity Method Investment, Aggregate Cost</a></td>
<td class="nump">$ 257<span></span>
</td>
<td class="nump">$ 257<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 257<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquityMethodInvestmentOwnershipPercentage', window );">Ownership percentage</a></td>
<td class="nump">25.90%<span></span>
</td>
<td class="nump">25.90%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">25.90%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_PaymentsToAcquireEquityMethodInvestments', window );">Payments to Acquire Equity Method Investments</a></td>
<td class="nump">$ 100<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1', window );">Noncash or Part Noncash Acquisition, Investments Acquired</a></td>
<td class="nump">$ 157<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_AlternativeInvestmentNetGainLoss">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Alternative Investment, Net Gain (Loss)</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_AlternativeInvestmentNetGainLoss</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Equity Method Investment, Amortization of Difference Between Carrying Amount and Underlying Equity</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_EquityMethodInvestmentChangeInCarryingValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Equity method investment, change in carrying value</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_EquityMethodInvestmentChangeInCarryingValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_EquityMethodInvestmentChangeInCarryingValueOther">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Equity Method Investment, Change In Carrying Value, Other</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_EquityMethodInvestmentChangeInCarryingValueOther</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AlternativeInvestment">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fair value of investment other than investment in equity security, investment in debt security and equity method investment. Includes, but is not limited to, investment in certain entities that calculate net asset value per share. Example includes, but is not limited to, investment in hedge fund, venture capital fund, private equity fund, and real estate partnership or fund.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 820<br> -SubTopic 10<br> -Section 50<br> -Paragraph 6A<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123874694&amp;loc=SL6742756-110258<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 820<br> -SubTopic 10<br> -Section 35<br> -Paragraph 54B<br> -URI http://asc.fasb.org/extlink&amp;oid=122636397&amp;loc=SL7495116-110257<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AlternativeInvestment</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EquityMethodInvestmentAggregateCost">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>This element represents the aggregate cost of investments accounted for under the equity method of accounting.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.12)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EquityMethodInvestmentAggregateCost</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EquityMethodInvestmentOwnershipPercentage">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The percentage of ownership of common stock or equity participation in the investee accounted for under the equity method of accounting.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (a)(1)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EquityMethodInvestmentOwnershipPercentage</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EquityMethodInvestmentQuotedMarketValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>This item represents the aggregate value of each identified investment accounted for under the equity method of accounting based on the quoted market price for those investments in common stock for which a quoted market price is available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EquityMethodInvestmentQuotedMarketValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EquityMethodInvestments">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>This item represents the carrying amount on the entity's balance sheet of its investment in common stock of an equity method investee. This is not an indicator of the fair value of the investment, rather it is the initial cost adjusted for the entity's share of earnings and losses of the investee, adjusted for any distributions (dividends) and other than temporary impairment (OTTI) losses recognized.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=109237563&amp;loc=d3e33749-111570<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 25<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8813-108599<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.12)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EquityMethodInvestments</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeLossFromEquityMethodInvestments">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of income (loss) for proportionate share of equity method investee's income (loss).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(12))<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(10))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(13)(f))<br> -URI http://asc.fasb.org/extlink&amp;oid=120399700&amp;loc=SL114874048-224260<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -Subparagraph (g)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=109237563&amp;loc=d3e33749-111570<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeLossFromEquityMethodInvestments</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The amount of investments that an Entity acquires in a noncash (or part noncash) acquisition. Noncash is defined as information about all investing and financing activities of an enterprise during a period that affect recognized assets or liabilities but that do not result in cash receipts or cash payments in the period. "Part noncash" refers to that portion of the transaction not resulting in cash receipts or cash payments in the period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 50<br> -Paragraph 5<br> -URI http://asc.fasb.org/extlink&amp;oid=123431023&amp;loc=d3e4332-108586<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=123431023&amp;loc=d3e4304-108586<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=123431023&amp;loc=d3e4313-108586<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PaymentsToAcquireEquityMethodInvestments">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The cash outflow associated with the purchase of or advances to an equity method investments, which are investments in joint ventures and entities in which the entity has an equity ownership interest normally of 20 to 50 percent and exercises significant influence.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 13<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3213-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PaymentsToAcquireEquityMethodInvestments</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InvestmentTypeAxis=srt_PartnershipInterestMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InvestmentTypeAxis=srt_PartnershipInterestMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_BusinessAcquisitionAxis=amgn_BeiGeneMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_BusinessAcquisitionAxis=amgn_BeiGeneMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_BusinessAcquisitionAxis=amgn_NeumoraTherapeuticsIncMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_BusinessAcquisitionAxis=amgn_NeumoraTherapeuticsIncMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>56
<FILENAME>R46.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304048437112">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Inventories (Details) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InventoryDisclosureAbstract', window );"><strong>Inventory Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InventoryRawMaterialsNetOfReserves', window );">Raw materials</a></td>
<td class="nump">$ 667<span></span>
</td>
<td class="nump">$ 486<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InventoryWorkInProcessNetOfReserves', window );">Work in process</a></td>
<td class="nump">2,313<span></span>
</td>
<td class="nump">2,437<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InventoryFinishedGoodsNetOfReserves', window );">Finished goods</a></td>
<td class="nump">1,172<span></span>
</td>
<td class="nump">970<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InventoryNet', window );">Total inventories</a></td>
<td class="nump">$ 4,152<span></span>
</td>
<td class="nump">$ 3,893<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InventoryDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InventoryDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InventoryFinishedGoodsNetOfReserves">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Carrying amount, net of valuation reserves and adjustments, as of the balance sheet date of merchandise or goods held by the company that are readily available for sale.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 330<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SAB Topic 5.BB)<br> -URI http://asc.fasb.org/extlink&amp;oid=27011343&amp;loc=d3e100047-122729<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(6)(a)(1))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InventoryFinishedGoodsNetOfReserves</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InventoryNet">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount after valuation and LIFO reserves of inventory expected to be sold, or consumed within one year or operating cycle, if longer.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124098289&amp;loc=d3e6676-107765<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.6(a))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InventoryNet</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InventoryRawMaterialsNetOfReserves">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Carrying amount, net of valuation reserves and adjustments, as of the balance sheet date of unprocessed items to be consumed in the manufacturing or production process.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 330<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SAB Topic 5.BB)<br> -URI http://asc.fasb.org/extlink&amp;oid=27011343&amp;loc=d3e100047-122729<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(6)(a)(4))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InventoryRawMaterialsNetOfReserves</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InventoryWorkInProcessNetOfReserves">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Carrying amount, net of reserves and adjustments, as of the balance sheet date of merchandise or goods which are partially completed. This inventory is generally comprised of raw materials, labor and factory overhead costs, which require further materials, labor and overhead to be converted into finished goods, and which generally require the use of estimates to determine percentage complete and pricing.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 330<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SAB Topic 5.BB)<br> -URI http://asc.fasb.org/extlink&amp;oid=27011343&amp;loc=d3e100047-122729<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(6)(a)(3))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InventoryWorkInProcessNetOfReserves</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>57
<FILENAME>R47.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304047192408">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Goodwill and other intangible assets (Goodwill Roll Forward) (Details)<br> $ in Millions</strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr><th class="th">
<div>Sep. 30, 2021 </div>
<div>USD ($)</div>
</th></tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_GoodwillRollForward', window );"><strong>Goodwill [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_Goodwill', window );">Beginning balance</a></td>
<td class="nump">$ 14,689<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_GoodwillForeignCurrencyTranslationGainLoss', window );">Currency translation adjustment</a></td>
<td class="num">(24)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_Goodwill', window );">Ending balance</a></td>
<td class="nump">$ 14,665<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_Goodwill">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount after accumulated impairment loss of an asset representing future economic benefits arising from other assets acquired in a business combination that are not individually identified and separately recognized.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03(10)(1))<br> -URI http://asc.fasb.org/extlink&amp;oid=120398452&amp;loc=d3e534808-122878<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 20<br> -Section 45<br> -Paragraph 5<br> -URI http://asc.fasb.org/extlink&amp;oid=120320667&amp;loc=SL49117168-202975<br><br>Reference 3: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 20<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=99380562&amp;loc=d3e13770-109266<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_Goodwill</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_GoodwillForeignCurrencyTranslationGainLoss">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of foreign currency translation gain (loss) which increases (decreases) an asset representing future economic benefits from other assets acquired in a business combination that are not individually identified and separately recognized.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=121556970&amp;loc=d3e13816-109267<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_GoodwillForeignCurrencyTranslationGainLoss</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_GoodwillRollForward">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_GoodwillRollForward</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>58
<FILENAME>R48.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304055962648">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Goodwill and other intangible assets (Identifiable Intangible Assets) (Details) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsLineItems', window );"><strong>Finite-Lived Intangible Assets [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsGross', window );">Gross carrying amounts</a></td>
<td class="nump">$ 32,001<span></span>
</td>
<td class="nump">$ 32,018<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization', window );">Accumulated amortization</a></td>
<td class="num">(17,372)<span></span>
</td>
<td class="num">(15,461)<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsNet', window );">Other intangible assets, net</a></td>
<td class="nump">14,629<span></span>
</td>
<td class="nump">16,557<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_IdentifiableIntangibleAssetsGross', window );">Gross carrying amount</a></td>
<td class="nump">32,031<span></span>
</td>
<td class="nump">32,048<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization', window );">Accumulated amortization</a></td>
<td class="num">(17,372)<span></span>
</td>
<td class="num">(15,461)<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IntangibleAssetsNetExcludingGoodwill', window );">Intangible assets, net</a></td>
<td class="nump">14,659<span></span>
</td>
<td class="nump">16,587<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis=us-gaap_InProcessResearchAndDevelopmentMember', window );">In-process Research and Development [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems', window );"><strong>Indefinite-lived Intangible Assets [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill', window );">Indefinite-lived intangible assets</a></td>
<td class="nump">30<span></span>
</td>
<td class="nump">30<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis=us-gaap_DevelopedTechnologyRightsMember', window );">Developed-Product-Technology Rights [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsLineItems', window );"><strong>Finite-Lived Intangible Assets [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsGross', window );">Gross carrying amounts</a></td>
<td class="nump">25,575<span></span>
</td>
<td class="nump">25,591<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization', window );">Accumulated amortization</a></td>
<td class="num">(12,222)<span></span>
</td>
<td class="num">(10,564)<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsNet', window );">Other intangible assets, net</a></td>
<td class="nump">13,353<span></span>
</td>
<td class="nump">15,027<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis=us-gaap_LicensingAgreementsMember', window );">Licensing Rights [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsLineItems', window );"><strong>Finite-Lived Intangible Assets [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsGross', window );">Gross carrying amounts</a></td>
<td class="nump">3,766<span></span>
</td>
<td class="nump">3,743<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization', window );">Accumulated amortization</a></td>
<td class="num">(2,931)<span></span>
</td>
<td class="num">(2,791)<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsNet', window );">Other intangible assets, net</a></td>
<td class="nump">835<span></span>
</td>
<td class="nump">952<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis=us-gaap_MarketingRelatedIntangibleAssetsMember', window );">Marketing-Related Rights [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsLineItems', window );"><strong>Finite-Lived Intangible Assets [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsGross', window );">Gross carrying amounts</a></td>
<td class="nump">1,362<span></span>
</td>
<td class="nump">1,367<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization', window );">Accumulated amortization</a></td>
<td class="num">(1,099)<span></span>
</td>
<td class="num">(1,041)<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsNet', window );">Other intangible assets, net</a></td>
<td class="nump">263<span></span>
</td>
<td class="nump">326<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis=amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember', window );">Research and Development Technology Rights [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsLineItems', window );"><strong>Finite-Lived Intangible Assets [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsGross', window );">Gross carrying amounts</a></td>
<td class="nump">1,298<span></span>
</td>
<td class="nump">1,317<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization', window );">Accumulated amortization</a></td>
<td class="num">(1,120)<span></span>
</td>
<td class="num">(1,065)<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsNet', window );">Other intangible assets, net</a></td>
<td class="nump">$ 178<span></span>
</td>
<td class="nump">$ 252<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_IdentifiableIntangibleAssetsAccumulatedAmortization">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Identifiable intangible assets accumulated amortization.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_IdentifiableIntangibleAssetsAccumulatedAmortization</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_IdentifiableIntangibleAssetsGross">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Identifiable intangible assets gross.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_IdentifiableIntangibleAssetsGross</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Accumulated amount of amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(1)<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16323-109275<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FiniteLivedIntangibleAssetsGross">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount before amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 928<br> -SubTopic 340<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=6473545&amp;loc=d3e61844-108004<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(1)<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16323-109275<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FiniteLivedIntangibleAssetsGross</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FiniteLivedIntangibleAssetsLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FiniteLivedIntangibleAssetsLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FiniteLivedIntangibleAssetsNet">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount after amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 926<br> -SubTopic 20<br> -Section 50<br> -Paragraph 5<br> -URI http://asc.fasb.org/extlink&amp;oid=120154696&amp;loc=d3e54445-107959<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(1)<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16323-109275<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FiniteLivedIntangibleAssetsNet</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of assets, excluding financial assets and goodwill, lacking physical substance and having a projected indefinite period of benefit.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16323-109275<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IntangibleAssetsNetExcludingGoodwill">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Sum of the carrying amounts of all intangible assets, excluding goodwill, as of the balance sheet date, net of accumulated amortization and impairment charges.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 2<br> -Subparagraph ((a)(1),(b))<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16323-109275<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=6388964&amp;loc=d3e16212-109274<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IntangibleAssetsNetExcludingGoodwill</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis=us-gaap_InProcessResearchAndDevelopmentMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis=us-gaap_InProcessResearchAndDevelopmentMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis=us-gaap_DevelopedTechnologyRightsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis=us-gaap_DevelopedTechnologyRightsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis=us-gaap_LicensingAgreementsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis=us-gaap_LicensingAgreementsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis=us-gaap_MarketingRelatedIntangibleAssetsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis=us-gaap_MarketingRelatedIntangibleAssetsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis=amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis=amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>59
<FILENAME>R49.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304142211560">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Goodwill and other intangible assets (Details Textual) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th" colspan="2">3 Months Ended</th>
<th class="th" colspan="2">9 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract', window );"><strong>Goodwill and Intangible Assets Disclosure [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AmortizationOfIntangibleAssets', window );">Amortization charges associated with finite-lived intangible assets</a></td>
<td class="nump">$ 642<span></span>
</td>
<td class="nump">$ 708<span></span>
</td>
<td class="nump">$ 1,900<span></span>
</td>
<td class="nump">$ 2,100<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear', window );">Total estimated amortization of finite-lived intangible assets for the six months ending December 31, 2021</a></td>
<td class="nump">600<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">600<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths', window );">Total estimated amortization of finite-lived intangible assets for 2022</a></td>
<td class="nump">2,500<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">2,500<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo', window );">Total estimated amortization of finite-lived intangible assets for 2023</a></td>
<td class="nump">2,400<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">2,400<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree', window );">Total estimated amortization of finite-lived intangible assets for 2024</a></td>
<td class="nump">2,400<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">2,400<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour', window );">Total estimated amortization of finite-lived intangible assets for 2025</a></td>
<td class="nump">2,200<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">2,200<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive', window );">Total estimated amortization of finite-lived intangible assets for 2026</a></td>
<td class="nump">$ 1,800<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 1,800<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AmortizationOfIntangibleAssets">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The aggregate expense charged against earnings to allocate the cost of intangible assets (nonphysical assets not used in production) in a systematic and rational manner to the periods expected to benefit from such assets. As a noncash expense, this element is added back to net income when calculating cash provided by or used in operations using the indirect method.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16323-109275<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 45<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=6388964&amp;loc=d3e16225-109274<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AmortizationOfIntangibleAssets</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of amortization for assets, excluding financial assets and goodwill, lacking physical substance with finite life expected to be recognized in next fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(3)<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16323-109275<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of amortization for assets, excluding financial assets and goodwill, lacking physical substance with finite life expected to be recognized in remainder of current fiscal year.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of amortization for assets, excluding financial assets and goodwill, lacking physical substance with finite life expected to be recognized in fifth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(3)<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16323-109275<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of amortization for assets, excluding financial assets and goodwill, lacking physical substance with finite life expected to be recognized in fourth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(3)<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16323-109275<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of amortization for assets, excluding financial assets and goodwill, lacking physical substance with finite life expected to be recognized in third fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(3)<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16323-109275<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of amortization for assets, excluding financial assets and goodwill, lacking physical substance with finite life expected to be recognized in second fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 350<br> -SubTopic 30<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)(3)<br> -URI http://asc.fasb.org/extlink&amp;oid=66006027&amp;loc=d3e16323-109275<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>60
<FILENAME>R50.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304041471736">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Financing arrangements (Principal Amounts and Carrying Value of Long-term Borrowings) (Details)<br> $ in Millions</strong></div></th>
<th class="th" colspan="1">3 Months Ended</th>
<th class="th" colspan="3"></th>
<th class="th" colspan="1"></th>
</tr>
<tr>
<th class="th">
<div>Sep. 30, 2021 </div>
<div>USD ($)</div>
</th>
<th class="th">
<div>Sep. 30, 2021 </div>
<div>EUR (&#8364;)</div>
</th>
<th class="th">
<div>Sep. 30, 2021 </div>
<div>CHF (SFr)</div>
</th>
<th class="th">
<div>Sep. 30, 2021 </div>
<div>GBP (&#163;)</div>
</th>
<th class="th">
<div>Dec. 31, 2020 </div>
<div>USD ($)</div>
</th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet', window );">Unamortized bond discounts, premiums and issuance costs, net</a></td>
<td class="num">$ (1,221)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">$ (1,188)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease', window );">Fair value adjustments</a></td>
<td class="nump">371<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">566<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherLongTermDebt', window );">Other</a></td>
<td class="nump">15<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">5<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongTermDebt', window );">Total carrying value of debt</a></td>
<td class="nump">37,579<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">32,986<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongTermDebtCurrent', window );">Less current portion</a></td>
<td class="num">(4,288)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(91)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongTermDebtNoncurrent', window );">Total long-term debt</a></td>
<td class="nump">33,291<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">32,895<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount</a></td>
<td class="nump">$ 5,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 1.25% &#8364;1,250 million notes due 2022 (1.25% 2022 euro Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">1.25%<span></span>
</td>
<td class="nump">1.25%<span></span>
</td>
<td class="nump">1.25%<span></span>
</td>
<td class="nump">1.25%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 1,448<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1,527<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount | &#8364;</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">&#8364; 1,250,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 2.70% notes due 2022 (2.70% 2022 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.70%<span></span>
</td>
<td class="nump">2.70%<span></span>
</td>
<td class="nump">2.70%<span></span>
</td>
<td class="nump">2.70%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 500<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">500<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 2.65% notes due 2022 (2.65% 2022 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.65%<span></span>
</td>
<td class="nump">2.65%<span></span>
</td>
<td class="nump">2.65%<span></span>
</td>
<td class="nump">2.65%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 1,500<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1,500<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 3.625% notes due 2022 (3.625% 2022 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">3.625%<span></span>
</td>
<td class="nump">3.625%<span></span>
</td>
<td class="nump">3.625%<span></span>
</td>
<td class="nump">3.625%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 750<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">750<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 0.41% CHF700 million bonds due 2023 (0.41% 2023 Swiss franc Bonds) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">0.41%<span></span>
</td>
<td class="nump">0.41%<span></span>
</td>
<td class="nump">0.41%<span></span>
</td>
<td class="nump">0.41%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 751<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">791<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount | SFr</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">SFr 700,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 2.25% notes due 2023 (2.25% 2023 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.25%<span></span>
</td>
<td class="nump">2.25%<span></span>
</td>
<td class="nump">2.25%<span></span>
</td>
<td class="nump">2.25%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 750<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">750<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 3.625% notes due 2024 (3.625% 2024 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">3.625%<span></span>
</td>
<td class="nump">3.625%<span></span>
</td>
<td class="nump">3.625%<span></span>
</td>
<td class="nump">3.625%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 1,400<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1,400<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 1.90% notes due 2025 (1.90% 2025 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">1.90%<span></span>
</td>
<td class="nump">1.90%<span></span>
</td>
<td class="nump">1.90%<span></span>
</td>
<td class="nump">1.90%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 500<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">500<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 3.125% notes due 2025 (3.125% 2025 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">3.125%<span></span>
</td>
<td class="nump">3.125%<span></span>
</td>
<td class="nump">3.125%<span></span>
</td>
<td class="nump">3.125%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 1,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1,000<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 2.00% &#8364;750 million notes due 2026 (2.00% 2026 euro Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.00%<span></span>
</td>
<td class="nump">2.00%<span></span>
</td>
<td class="nump">2.00%<span></span>
</td>
<td class="nump">2.00%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 869<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">916<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount | &#8364;</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">&#8364; 750,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 2.60% notes due 2026 (2.60% 2026 notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.60%<span></span>
</td>
<td class="nump">2.60%<span></span>
</td>
<td class="nump">2.60%<span></span>
</td>
<td class="nump">2.60%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 1,250<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1,250<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 5.50% &#163;475 million notes due 2026 (5.50% 2026 pound sterling Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">5.50%<span></span>
</td>
<td class="nump">5.50%<span></span>
</td>
<td class="nump">5.50%<span></span>
</td>
<td class="nump">5.50%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 640<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">649<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount | &#163;</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">&#163; 475,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 2.20% notes due 2027 (2.20% 2027 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.20%<span></span>
</td>
<td class="nump">2.20%<span></span>
</td>
<td class="nump">2.20%<span></span>
</td>
<td class="nump">2.20%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 1,750<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1,750<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 3.20% notes due 2027 (3.20% 2027 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">3.20%<span></span>
</td>
<td class="nump">3.20%<span></span>
</td>
<td class="nump">3.20%<span></span>
</td>
<td class="nump">3.20%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 1,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1,000<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 1.65% notes due 2028 (1.65% 2028 Notes) [Member}</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">1.65%<span></span>
</td>
<td class="nump">1.65%<span></span>
</td>
<td class="nump">1.65%<span></span>
</td>
<td class="nump">1.65%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 1,250<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount</a></td>
<td class="nump">$ 1,250<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent', window );">Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event</a></td>
<td class="nump">101.00%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 4.00% &#163;700 million notes due 2029 (4.00% 2029 pound sterling Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">4.00%<span></span>
</td>
<td class="nump">4.00%<span></span>
</td>
<td class="nump">4.00%<span></span>
</td>
<td class="nump">4.00%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 943<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">957<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount | &#163;</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">&#163; 700,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 2.45% notes due 2030 (2.45% 2030 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.45%<span></span>
</td>
<td class="nump">2.45%<span></span>
</td>
<td class="nump">2.45%<span></span>
</td>
<td class="nump">2.45%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 1,250<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1,250<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 2.30% notes due 2031 (2.30% 2031 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.30%<span></span>
</td>
<td class="nump">2.30%<span></span>
</td>
<td class="nump">2.30%<span></span>
</td>
<td class="nump">2.30%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 1,250<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1,250<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 2.00% notes due 2032 (2.00% 2032 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.00%<span></span>
</td>
<td class="nump">2.00%<span></span>
</td>
<td class="nump">2.00%<span></span>
</td>
<td class="nump">2.00%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 1,250<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount</a></td>
<td class="nump">$ 1,250<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent', window );">Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event</a></td>
<td class="nump">101.00%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 6.375% notes due 2037 (6.375% 2037 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">6.375%<span></span>
</td>
<td class="nump">6.375%<span></span>
</td>
<td class="nump">6.375%<span></span>
</td>
<td class="nump">6.375%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 478<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">478<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 6.90% notes due 2038 (6.90% 2038 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">6.90%<span></span>
</td>
<td class="nump">6.90%<span></span>
</td>
<td class="nump">6.90%<span></span>
</td>
<td class="nump">6.90%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 254<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">254<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 6.40% notes due 2039 (6.40% 2039 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">6.40%<span></span>
</td>
<td class="nump">6.40%<span></span>
</td>
<td class="nump">6.40%<span></span>
</td>
<td class="nump">6.40%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 333<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">333<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 3.15% notes due 2040 (3.15% 2040 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">3.15%<span></span>
</td>
<td class="nump">3.15%<span></span>
</td>
<td class="nump">3.15%<span></span>
</td>
<td class="nump">3.15%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 2,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">2,000<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 5.75% notes due 2040 (5.75% 2040 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">5.75%<span></span>
</td>
<td class="nump">5.75%<span></span>
</td>
<td class="nump">5.75%<span></span>
</td>
<td class="nump">5.75%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 373<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">373<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 2.80% notes due 2041 (2.80% 2041 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.80%<span></span>
</td>
<td class="nump">2.80%<span></span>
</td>
<td class="nump">2.80%<span></span>
</td>
<td class="nump">2.80%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 1,150<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount</a></td>
<td class="nump">$ 1,150<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent', window );">Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event</a></td>
<td class="nump">101.00%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 4.95% notes due 2041 (4.95% 2041 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">4.95%<span></span>
</td>
<td class="nump">4.95%<span></span>
</td>
<td class="nump">4.95%<span></span>
</td>
<td class="nump">4.95%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 600<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">600<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 5.15% notes due 2041 (5.15% 2041 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">5.15%<span></span>
</td>
<td class="nump">5.15%<span></span>
</td>
<td class="nump">5.15%<span></span>
</td>
<td class="nump">5.15%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 729<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">729<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 5.65% notes due 2042 (5.65% 2042 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">5.65%<span></span>
</td>
<td class="nump">5.65%<span></span>
</td>
<td class="nump">5.65%<span></span>
</td>
<td class="nump">5.65%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 415<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">415<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 5.375% notes due 2043 (5.375% 2043 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">5.375%<span></span>
</td>
<td class="nump">5.375%<span></span>
</td>
<td class="nump">5.375%<span></span>
</td>
<td class="nump">5.375%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 185<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">185<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 4.40% notes due 2045 (4.40% 2045 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">4.40%<span></span>
</td>
<td class="nump">4.40%<span></span>
</td>
<td class="nump">4.40%<span></span>
</td>
<td class="nump">4.40%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 2,250<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">2,250<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 4.563% notes due 2048 (4.563% 2048 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">4.563%<span></span>
</td>
<td class="nump">4.563%<span></span>
</td>
<td class="nump">4.563%<span></span>
</td>
<td class="nump">4.563%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 1,415<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1,415<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 3.375% notes due 2050 (3.375% 2050 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">3.375%<span></span>
</td>
<td class="nump">3.375%<span></span>
</td>
<td class="nump">3.375%<span></span>
</td>
<td class="nump">3.375%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 2,250<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">2,250<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 4.663% notes due 2051 (4.663% 2051 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">4.663%<span></span>
</td>
<td class="nump">4.663%<span></span>
</td>
<td class="nump">4.663%<span></span>
</td>
<td class="nump">4.663%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 3,541<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">3,541<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 3.00% notes due 2052 (3.00% 2052 Notes)</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">3.00%<span></span>
</td>
<td class="nump">3.00%<span></span>
</td>
<td class="nump">3.00%<span></span>
</td>
<td class="nump">3.00%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 1,350<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount</a></td>
<td class="nump">$ 1,350<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent', window );">Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event</a></td>
<td class="nump">101.00%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | Two Point Seven Seven Percent Notes Due Two Zero Five Three</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.77%<span></span>
</td>
<td class="nump">2.77%<span></span>
</td>
<td class="nump">2.77%<span></span>
</td>
<td class="nump">2.77%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 940<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">940<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | Other notes due 2097 [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentCarryingAmount', window );">Long-term debt, gross</a></td>
<td class="nump">$ 100<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 100<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentCarryingAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount, before unamortized (discount) premium and debt issuance costs, of long-term debt. Includes, but is not limited to, notes payable, bonds payable, commercial loans, mortgage loans, convertible debt, subordinated debt and other types of debt.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (b)(1)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466204&amp;loc=SL6031897-161870<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(16))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400017&amp;loc=d3e572229-122910<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(22))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03(16))<br> -URI http://asc.fasb.org/extlink&amp;oid=120398452&amp;loc=d3e534808-122878<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentCarryingAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentFaceAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Face (par) amount of debt instrument at time of issuance.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1B<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495323-112611<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 835<br> -SubTopic 30<br> -Section 45<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=124435984&amp;loc=d3e28551-108399<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 835<br> -SubTopic 30<br> -Section 55<br> -Paragraph 8<br> -URI http://asc.fasb.org/extlink&amp;oid=114775985&amp;loc=d3e28878-108400<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 835<br> -SubTopic 30<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=124429444&amp;loc=SL124452920-239629<br><br>Reference 5: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69C<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495737-112612<br><br>Reference 6: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69B<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495735-112612<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentFaceAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentInterestRateStatedPercentage">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Contractual interest rate for funds borrowed, under the debt agreement.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1B<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495323-112611<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.22(a)(1))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentInterestRateStatedPercentage</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of unamortized debt discount (premium) and debt issuance costs.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69C<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495737-112612<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (b)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466204&amp;loc=SL6031897-161870<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1D<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495340-112611<br><br>Reference 4: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69B<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495735-112612<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 835<br> -SubTopic 30<br> -Section 45<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=124435984&amp;loc=d3e28555-108399<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of cumulative increase (decrease) in fair value of hedged liability in fair value hedge, attributable to hedged risk.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4EE<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL109999712-113959<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LongTermDebt">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount, after unamortized (discount) premium and debt issuance costs, of long-term debt. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (b)(3)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466204&amp;loc=SL6031897-161870<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69C<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495737-112612<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(a)(16))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400017&amp;loc=d3e572229-122910<br><br>Reference 4: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69B<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495735-112612<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03(16))<br> -URI http://asc.fasb.org/extlink&amp;oid=120398452&amp;loc=d3e534808-122878<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1D<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495340-112611<br><br>Reference 7: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(22))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LongTermDebt</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LongTermDebtCurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount, after unamortized (discount) premium and debt issuance costs, of long-term debt, classified as current. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.19,20)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LongTermDebtCurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LongTermDebtNoncurrent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount after unamortized (discount) premium and debt issuance costs of long-term debt classified as noncurrent and excluding amounts to be repaid within one year or the normal operating cycle, if longer. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.22)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LongTermDebtNoncurrent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherLongTermDebt">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of long-term debt classified as other.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(22))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(a)(16))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400017&amp;loc=d3e572229-122910<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03(16))<br> -URI http://asc.fasb.org/extlink&amp;oid=120398452&amp;loc=d3e534808-122878<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherLongTermDebt</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointSixFiveNotesDue2022Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointSixFiveNotesDue2022Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_ThreePointSixTwoFivePercentNotesDue2022Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_ThreePointSixTwoFivePercentNotesDue2022Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_ThreePointSixTwoFivePercentNotesDue2024Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_ThreePointSixTwoFivePercentNotesDue2024Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_ThreePointTwoZeroNotesDue2027Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_ThreePointTwoZeroNotesDue2027Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_OnePointSixFivePercent2028NotesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_OnePointSixFivePercent2028NotesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_FourPercentPoundSterlingNotesDue2029Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_FourPercentPoundSterlingNotesDue2029Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointFourFivePercentNotesDue2030Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointFourFivePercentNotesDue2030Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointThreeZeroPercentNotesDue2031Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointThreeZeroPercentNotesDue2031Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointZeroPercent2032NotesMemberMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointZeroPercent2032NotesMemberMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_SixPointThreeSevenFivePercentNotesDue2037Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_SixPointThreeSevenFivePercentNotesDue2037Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_SixPointNineZeroPercentNotesDue2038Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_SixPointNineZeroPercentNotesDue2038Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_SixPointFourZeroPercentNotesDue2039Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_SixPointFourZeroPercentNotesDue2039Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_ThreePointOneFivePercentNotesDue2040Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_ThreePointOneFivePercentNotesDue2040Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_FivePointSevenFivePercentNotesDue2040Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_FivePointSevenFivePercentNotesDue2040Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointEightZeroPercent2041NotesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointEightZeroPercent2041NotesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_FourPointNineFivePercentNotesDue2041Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_FourPointNineFivePercentNotesDue2041Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_FivePointOneFivePercentNotesDue2041Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_FivePointOneFivePercentNotesDue2041Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_FivePointSixFivePercentNotesDue2042Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_FivePointSixFivePercentNotesDue2042Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_FivePointThreeSevenFivePercentNotesDue2043Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_FivePointThreeSevenFivePercentNotesDue2043Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_ThreePointThreeSevenFivePercentNotesDue2050Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_ThreePointThreeSevenFivePercentNotesDue2050Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_A300NotesDue20523002052NotesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_A300NotesDue20523002052NotesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_OtherNotesDue2097Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_OtherNotesDue2097Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>61
<FILENAME>R51.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051193000">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Financing arrangements (Details Textual)<br> $ in Millions</strong></div></th>
<th class="th" colspan="1">3 Months Ended</th>
<th class="th" colspan="1">9 Months Ended</th>
</tr>
<tr>
<th class="th">
<div>Sep. 30, 2021 </div>
<div>USD ($)</div>
</th>
<th class="th">
<div>Sep. 30, 2021 </div>
<div>USD ($)</div>
</th>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount</a></td>
<td class="nump">$ 5,000<span></span>
</td>
<td class="nump">$ 5,000<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 4.563% notes due 2048 (4.563% 2048 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">4.563%<span></span>
</td>
<td class="nump">4.563%<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateEffectivePercentage', window );">Effective interest rate</a></td>
<td class="nump">6.30%<span></span>
</td>
<td class="nump">6.30%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 4.663% notes due 2051 (4.663% 2051 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">4.663%<span></span>
</td>
<td class="nump">4.663%<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateEffectivePercentage', window );">Effective interest rate</a></td>
<td class="nump">5.60%<span></span>
</td>
<td class="nump">5.60%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | Two Point Seven Seven Percent Notes Due Two Zero Five Three</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.77%<span></span>
</td>
<td class="nump">2.77%<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateEffectivePercentage', window );">Effective interest rate</a></td>
<td class="nump">5.20%<span></span>
</td>
<td class="nump">5.20%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 1.65% notes due 2028 (1.65% 2028 Notes) [Member}</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">1.65%<span></span>
</td>
<td class="nump">1.65%<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount</a></td>
<td class="nump">$ 1,250<span></span>
</td>
<td class="nump">$ 1,250<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent', window );">Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event</a></td>
<td class="nump">101.00%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 2.00% notes due 2032 (2.00% 2032 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.00%<span></span>
</td>
<td class="nump">2.00%<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount</a></td>
<td class="nump">$ 1,250<span></span>
</td>
<td class="nump">$ 1,250<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent', window );">Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event</a></td>
<td class="nump">101.00%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 2.80% notes due 2041 (2.80% 2041 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.80%<span></span>
</td>
<td class="nump">2.80%<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount</a></td>
<td class="nump">$ 1,150<span></span>
</td>
<td class="nump">$ 1,150<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent', window );">Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event</a></td>
<td class="nump">101.00%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember', window );">Notes [Member] | 3.00% notes due 2052 (3.00% 2052 Notes)</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">3.00%<span></span>
</td>
<td class="nump">3.00%<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentFaceAmount', window );">Face amount</a></td>
<td class="nump">$ 1,350<span></span>
</td>
<td class="nump">$ 1,350<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent', window );">Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event</a></td>
<td class="nump">101.00%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_RangeAxis=srt_MinimumMember', window );">Minimum [Member] | Debt Securities Payable [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount', window );">Debt Instrument, Redemption Period without Payment of Make Whole Amount</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">2 months<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_RangeAxis=srt_MaximumMember', window );">Maximum [Member] | Debt Securities Payable [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount', window );">Debt Instrument, Redemption Period without Payment of Make Whole Amount</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">6 months<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Debt Instrument, Redemption Period without Payment of Make Whole Amount</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:durationItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentFaceAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Face (par) amount of debt instrument at time of issuance.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1B<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495323-112611<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 835<br> -SubTopic 30<br> -Section 45<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=124435984&amp;loc=d3e28551-108399<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 835<br> -SubTopic 30<br> -Section 55<br> -Paragraph 8<br> -URI http://asc.fasb.org/extlink&amp;oid=114775985&amp;loc=d3e28878-108400<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 835<br> -SubTopic 30<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=124429444&amp;loc=SL124452920-239629<br><br>Reference 5: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69C<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495737-112612<br><br>Reference 6: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69B<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495735-112612<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentFaceAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentInterestRateEffectivePercentage">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Effective interest rate for the funds borrowed under the debt agreement considering interest compounding and original issue discount or premium.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 6<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466204&amp;loc=SL6036836-161870<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 835<br> -SubTopic 30<br> -Section 45<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=124435984&amp;loc=d3e28551-108399<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 835<br> -SubTopic 30<br> -Section 50<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=124429444&amp;loc=SL124452920-239629<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.22(a)(1))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentInterestRateEffectivePercentage</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentInterestRateStatedPercentage">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Contractual interest rate for funds borrowed, under the debt agreement.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1B<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495323-112611<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.22(a)(1))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentInterestRateStatedPercentage</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_OnePointSixFivePercent2028NotesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_OnePointSixFivePercent2028NotesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointZeroPercent2032NotesMemberMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointZeroPercent2032NotesMemberMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointEightZeroPercent2041NotesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointEightZeroPercent2041NotesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_A300NotesDue20523002052NotesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_A300NotesDue20523002052NotesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_RangeAxis=srt_MinimumMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_RangeAxis=srt_MinimumMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LongtermDebtTypeAxis=us-gaap_DebtSecuritiesPayableMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LongtermDebtTypeAxis=us-gaap_DebtSecuritiesPayableMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_RangeAxis=srt_MaximumMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_RangeAxis=srt_MaximumMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>62
<FILENAME>R52.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304056006184">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Financing arrangements (interest rate swaps textual interim only) (Details) - Notes [Member]<br> $ in Millions</strong></div></th>
<th class="th">
<div>Sep. 30, 2021 </div>
<div>USD ($)</div>
</th>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointFourFivePercentNotesDue2030Member', window );">2.45% notes due 2030 (2.45% 2030 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeNotionalAmount', window );">Notional amounts</a></td>
<td class="nump">$ 1,000<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.45%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointFourFivePercentNotesDue2030Member', window );">2.45% notes due 2030 (2.45% 2030 Notes) [Member] | London Interbank Offered Rate (LIBOR) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeBasisSpreadOnVariableRate', window );">Derivative, Basis Spread on Variable Rate</a></td>
<td class="nump">1.00%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointThreeZeroPercentNotesDue2031Member', window );">2.30% notes due 2031 (2.30% 2031 Notes) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeNotionalAmount', window );">Notional amounts</a></td>
<td class="nump">$ 500<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.30%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointThreeZeroPercentNotesDue2031Member', window );">2.30% notes due 2031 (2.30% 2031 Notes) [Member] | London Interbank Offered Rate (LIBOR) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentLineItems', window );"><strong>Debt Instrument [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeBasisSpreadOnVariableRate', window );">Derivative, Basis Spread on Variable Rate</a></td>
<td class="nump">0.80%<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentInterestRateStatedPercentage">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Contractual interest rate for funds borrowed, under the debt agreement.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1B<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495323-112611<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.22(a)(1))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentInterestRateStatedPercentage</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeBasisSpreadOnVariableRate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The percentage points added to the reference rate to compute the variable rate on the interest rate derivative.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeBasisSpreadOnVariableRate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeNotionalAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Nominal or face amount used to calculate payment on derivative.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1B<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL5580258-113959<br><br>Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1A<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL5579245-113959<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeNotionalAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointFourFivePercentNotesDue2030Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointFourFivePercentNotesDue2030Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_VariableRateAxis=us-gaap_LondonInterbankOfferedRateLIBORMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_VariableRateAxis=us-gaap_LondonInterbankOfferedRateLIBORMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointThreeZeroPercentNotesDue2031Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointThreeZeroPercentNotesDue2031Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>63
<FILENAME>R53.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304143851704">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Stockholders' equity (Share Repurchase Program) (Details) - USD ($)<br> shares in Millions, $ in Millions</strong></div></th>
<th class="th" colspan="6">3 Months Ended</th>
<th class="th" colspan="2">9 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Jun. 30, 2021</div></th>
<th class="th"><div>Mar. 31, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Jun. 30, 2020</div></th>
<th class="th"><div>Mar. 31, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquityAbstract', window );"><strong>Equity [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchasedDuringPeriodShares', window );">Stock repurchased, Shares</a></td>
<td class="nump">4.6<span></span>
</td>
<td class="nump">6.5<span></span>
</td>
<td class="nump">3.7<span></span>
</td>
<td class="nump">3.0<span></span>
</td>
<td class="nump">2.6<span></span>
</td>
<td class="nump">4.3<span></span>
</td>
<td class="nump">14.8<span></span>
</td>
<td class="nump">9.9<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchasedDuringPeriodValue', window );">Stock repurchased</a></td>
<td class="nump">$ 1,069<span></span>
</td>
<td class="nump">$ 1,592<span></span>
</td>
<td class="nump">$ 865<span></span>
</td>
<td class="nump">$ 752<span></span>
</td>
<td class="nump">$ 591<span></span>
</td>
<td class="nump">$ 933<span></span>
</td>
<td class="nump">$ 3,526<span></span>
</td>
<td class="nump">$ 2,276<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EquityAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EquityAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockRepurchasedDuringPeriodShares">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Number of shares that have been repurchased during the period and have not been retired and are not held in treasury. Some state laws may govern the circumstances under which an entity may acquire its own stock and prescribe the accounting treatment therefore. This element is used when state law does not recognize treasury stock.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=d3e21463-112644<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -URI http://asc.fasb.org/extlink&amp;oid=120397183&amp;loc=d3e187085-122770<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(28))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockRepurchasedDuringPeriodShares</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:sharesItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockRepurchasedDuringPeriodValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Equity impact of the value of stock that has been repurchased during the period and has not been retired and is not held in treasury. Some state laws may mandate the circumstances under which an entity may acquire its own stock and prescribe the accounting treatment therefore. This element is used when state law does not recognize treasury stock.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(28))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -URI http://asc.fasb.org/extlink&amp;oid=123467817&amp;loc=d3e21463-112644<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -URI http://asc.fasb.org/extlink&amp;oid=120397183&amp;loc=d3e187085-122770<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockRepurchasedDuringPeriodValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>64
<FILENAME>R54.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051978472">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Stockholders' equity (Details Textual) (Details) - USD ($)<br></strong></div></th>
<th class="th" colspan="1"></th>
<th class="th" colspan="6">1 Months Ended</th>
<th class="th" colspan="4">3 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Dec. 08, 2021</div></th>
<th class="th"><div>Oct. 31, 2021</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Jul. 31, 2021</div></th>
<th class="th"><div>Jun. 30, 2021</div></th>
<th class="th"><div>Mar. 31, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Mar. 31, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Mar. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ClassOfStockLineItems', window );"><strong>Class of Stock [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchaseProgramAuthorizedAmount1', window );">Stock repurchase program, additional authorized amount</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 3,400,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1', window );">Amount available for stock repurchases under a board approved stock repurchase plan</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 2,900,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 2,900,000,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockDividendsPerShareDeclared', window );">Dividends declared per share (in usd per share)</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="nump">$ 1.60<span></span>
</td>
<td class="nump">$ 1.60<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockDividendsPerShareCashPaid', window );">Dividends paid per share (in usd per share)</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_SubsequentEventTypeAxis=us-gaap_SubsequentEventMember', window );">Subsequent Event [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ClassOfStockLineItems', window );"><strong>Class of Stock [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockDividendsPerShareDeclared', window );">Dividends declared per share (in usd per share)</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_StatementScenarioAxis=srt_ScenarioForecastMember', window );">Forecast [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ClassOfStockLineItems', window );"><strong>Class of Stock [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_CommonStockDividendsPerShareCashPaid', window );">Dividends paid per share (in usd per share)</a></td>
<td class="nump">$ 1.76<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ClassOfStockLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ClassOfStockLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommonStockDividendsPerShareCashPaid">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Aggregate dividends paid during the period for each share of common stock outstanding.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -URI http://asc.fasb.org/extlink&amp;oid=120397183&amp;loc=d3e187085-122770<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommonStockDividendsPerShareCashPaid</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_CommonStockDividendsPerShareDeclared">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Aggregate dividends declared during the period for each share of common stock outstanding.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 505<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.3-04)<br> -URI http://asc.fasb.org/extlink&amp;oid=120397183&amp;loc=d3e187085-122770<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_CommonStockDividendsPerShareDeclared</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:perShareItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockRepurchaseProgramAuthorizedAmount1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of stock repurchase plan authorized.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockRepurchaseProgramAuthorizedAmount1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount remaining of a stock repurchase plan authorized.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SubsequentEventTypeAxis=us-gaap_SubsequentEventMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SubsequentEventTypeAxis=us-gaap_SubsequentEventMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_StatementScenarioAxis=srt_ScenarioForecastMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_StatementScenarioAxis=srt_ScenarioForecastMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>65
<FILENAME>R55.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051035176">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Stockholders' equity (Components of AOCI) (Details) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th" colspan="4">3 Months Ended</th>
<th class="th" colspan="2">9 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Jun. 30, 2021</div></th>
<th class="th"><div>Mar. 31, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward', window );"><strong>Increase (Decrease) in AOCI [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of beginning of period</a></td>
<td class="nump">$ 8,247<span></span>
</td>
<td class="nump">$ 9,334<span></span>
</td>
<td class="nump">$ 9,409<span></span>
</td>
<td class="nump">$ 10,659<span></span>
</td>
<td class="nump">$ 9,409<span></span>
</td>
<td class="nump">$ 9,673<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent', window );">Foreign currency translation adjustments</a></td>
<td class="num">(35)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">14<span></span>
</td>
<td class="num">(60)<span></span>
</td>
<td class="num">(41)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of end of period</a></td>
<td class="nump">8,217<span></span>
</td>
<td class="nump">8,247<span></span>
</td>
<td class="nump">9,334<span></span>
</td>
<td class="nump">10,959<span></span>
</td>
<td class="nump">8,217<span></span>
</td>
<td class="nump">10,959<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedTranslationAdjustmentMember', window );">Foreign currency translation [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward', window );"><strong>Increase (Decrease) in AOCI [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of beginning of period</a></td>
<td class="num">(734)<span></span>
</td>
<td class="num">(748)<span></span>
</td>
<td class="num">(709)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(709)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent', window );">Foreign currency translation adjustments</a></td>
<td class="num">(35)<span></span>
</td>
<td class="nump">14<span></span>
</td>
<td class="num">(39)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1', window );">Income taxes</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of end of period</a></td>
<td class="num">(769)<span></span>
</td>
<td class="num">(734)<span></span>
</td>
<td class="num">(748)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(769)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember', window );">Cash&#160;flow hedges [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward', window );"><strong>Increase (Decrease) in AOCI [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of beginning of period</a></td>
<td class="num">(121)<span></span>
</td>
<td class="num">(73)<span></span>
</td>
<td class="num">(263)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(263)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent', window );">Unrealized gains</a></td>
<td class="nump">16<span></span>
</td>
<td class="num">(31)<span></span>
</td>
<td class="nump">108<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent', window );">Reclassification adjustments to income</a></td>
<td class="nump">109<span></span>
</td>
<td class="num">(28)<span></span>
</td>
<td class="nump">133<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1', window );">Income taxes</a></td>
<td class="num">(26)<span></span>
</td>
<td class="nump">11<span></span>
</td>
<td class="num">(51)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of end of period</a></td>
<td class="num">(22)<span></span>
</td>
<td class="num">(121)<span></span>
</td>
<td class="num">(73)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(22)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember', window );">Available-for-sale securities [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward', window );"><strong>Increase (Decrease) in AOCI [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of beginning of period</a></td>
<td class="nump">1<span></span>
</td>
<td class="nump">1<span></span>
</td>
<td class="nump">1<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">1<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent', window );">Unrealized gains</a></td>
<td class="num">(1)<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent', window );">Reclassification adjustments to income</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1', window );">Income taxes</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of end of period</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">1<span></span>
</td>
<td class="nump">1<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StatementEquityComponentsAxis=amgn_AccumulatedOtherAdjustmentAttributabletoParentMember', window );">Other [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward', window );"><strong>Increase (Decrease) in AOCI [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of beginning of period</a></td>
<td class="num">(14)<span></span>
</td>
<td class="num">(13)<span></span>
</td>
<td class="num">(14)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(14)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent', window );">Unrealized gains</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax', window );">Other</a></td>
<td class="num">(3)<span></span>
</td>
<td class="num">(1)<span></span>
</td>
<td class="nump">1<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of end of period</a></td>
<td class="num">(17)<span></span>
</td>
<td class="num">(14)<span></span>
</td>
<td class="num">(13)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(17)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedOtherComprehensiveIncomeMember', window );">AOCI [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward', window );"><strong>Increase (Decrease) in AOCI [Roll Forward]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of beginning of period</a></td>
<td class="num">(868)<span></span>
</td>
<td class="num">(833)<span></span>
</td>
<td class="num">(985)<span></span>
</td>
<td class="num">(783)<span></span>
</td>
<td class="num">(985)<span></span>
</td>
<td class="num">(528)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent', window );">Foreign currency translation adjustments</a></td>
<td class="num">(35)<span></span>
</td>
<td class="nump">14<span></span>
</td>
<td class="num">(39)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent', window );">Unrealized gains</a></td>
<td class="nump">15<span></span>
</td>
<td class="num">(31)<span></span>
</td>
<td class="nump">108<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent', window );">Reclassification adjustments to income</a></td>
<td class="nump">109<span></span>
</td>
<td class="num">(28)<span></span>
</td>
<td class="nump">133<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax', window );">Other</a></td>
<td class="num">(3)<span></span>
</td>
<td class="num">(1)<span></span>
</td>
<td class="nump">1<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1', window );">Income taxes</a></td>
<td class="num">(26)<span></span>
</td>
<td class="nump">11<span></span>
</td>
<td class="num">(51)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_StockholdersEquity', window );">Balance as of end of period</a></td>
<td class="num">$ (808)<span></span>
</td>
<td class="num">$ (868)<span></span>
</td>
<td class="num">$ (833)<span></span>
</td>
<td class="num">$ (903)<span></span>
</td>
<td class="num">$ (808)<span></span>
</td>
<td class="num">$ (903)<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Other Comprehensive Income (Loss), Other Adjustment, before Tax</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncreaseDecreaseInStockholdersEquityRollForward</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount before tax and reclassification adjustments of other comprehensive income (loss) attributable to parent.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 14A<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669686-108580<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount after tax and reclassification adjustments of gain (loss) on foreign currency translation adjustments, foreign currency transactions designated and effective as economic hedges of a net investment in a foreign entity and intra-entity foreign currency transactions that are of a long-term-investment nature, attributable to parent entity.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 45<br> -Paragraph 20<br> -URI http://asc.fasb.org/extlink&amp;oid=123454820&amp;loc=SL4569643-111683<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1A<br> -Subparagraph (c)(3)<br> -URI http://asc.fasb.org/extlink&amp;oid=109239629&amp;loc=SL4573702-111684<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 45<br> -Paragraph 19<br> -URI http://asc.fasb.org/extlink&amp;oid=123454820&amp;loc=SL4569616-111683<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of tax expense (benefit) allocated to other comprehensive income (loss) attributable to parent entity.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 45<br> -Paragraph 20<br> -URI http://asc.fasb.org/extlink&amp;oid=123454820&amp;loc=SL4569643-111683<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 45<br> -Paragraph 19<br> -URI http://asc.fasb.org/extlink&amp;oid=123454820&amp;loc=SL4569616-111683<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 810<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1A<br> -Subparagraph (c)(3)<br> -URI http://asc.fasb.org/extlink&amp;oid=109239629&amp;loc=SL4573702-111684<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount before tax of reclassification adjustments of other comprehensive income (loss) attributable to parent.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 14A<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669686-108580<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StockholdersEquity">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Total of all stockholders' equity (deficit) items, net of receivables from officers, directors, owners, and affiliates of the entity which are attributable to the parent. The amount of the economic entity's stockholders' equity attributable to the parent excludes the amount of stockholders' equity which is allocable to that ownership interest in subsidiary equity which is not attributable to the parent (noncontrolling interest, minority interest). This excludes temporary equity and is sometimes called permanent equity.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 852<br> -SubTopic 10<br> -Section 55<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=84165509&amp;loc=d3e56426-112766<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 310<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SAB Topic 4.E)<br> -URI http://asc.fasb.org/extlink&amp;oid=122038336&amp;loc=d3e74512-122707<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(31))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(29))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(30))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br><br>Reference 7: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123596393&amp;loc=d3e14064-108612<br><br>Reference 8: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StockholdersEquity</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedTranslationAdjustmentMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedTranslationAdjustmentMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementEquityComponentsAxis=amgn_AccumulatedOtherAdjustmentAttributabletoParentMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementEquityComponentsAxis=amgn_AccumulatedOtherAdjustmentAttributabletoParentMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedOtherComprehensiveIncomeMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedOtherComprehensiveIncomeMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>66
<FILENAME>R56.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304050238872">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Stockholders' equity (Reclassifications out of AOCI) (Details) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th" colspan="6">3 Months Ended</th>
<th class="th" colspan="2">9 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Jun. 30, 2021</div></th>
<th class="th"><div>Mar. 31, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Jun. 30, 2020</div></th>
<th class="th"><div>Mar. 31, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems', window );"><strong>Reclassification out of Accumulated Other Comprehensive Income [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">$ 6,706<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 6,423<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 19,133<span></span>
</td>
<td class="nump">$ 18,790<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NonoperatingIncomeExpense', window );">Other income, net</a></td>
<td class="nump">73<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">55<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">97<span></span>
</td>
<td class="nump">69<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments', window );">Income before income taxes</a></td>
<td class="nump">2,155<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">2,206<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">4,570<span></span>
</td>
<td class="nump">6,256<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncomeTaxExpenseBenefit', window );">Provision for income taxes</a></td>
<td class="num">(271)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(185)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(576)<span></span>
</td>
<td class="num">(607)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income</a></td>
<td class="nump">1,884<span></span>
</td>
<td class="nump">$ 464<span></span>
</td>
<td class="nump">$ 1,646<span></span>
</td>
<td class="nump">2,021<span></span>
</td>
<td class="nump">$ 1,803<span></span>
</td>
<td class="nump">$ 1,825<span></span>
</td>
<td class="nump">3,994<span></span>
</td>
<td class="nump">5,649<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=us-gaap_ProductMember', window );">Product sales [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems', window );"><strong>Reclassification out of Accumulated Other Comprehensive Income [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">6,320<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">6,104<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">18,026<span></span>
</td>
<td class="nump">17,906<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis=us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember', window );">Reclassification out of Accumulated Other Comprehensive Income [Member] | Cash&#160;flow hedges [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems', window );"><strong>Reclassification out of Accumulated Other Comprehensive Income [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments', window );">Income before income taxes</a></td>
<td class="num">(109)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">224<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(214)<span></span>
</td>
<td class="nump">259<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncomeTaxExpenseBenefit', window );">Provision for income taxes</a></td>
<td class="nump">23<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(49)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">45<span></span>
</td>
<td class="num">(57)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income</a></td>
<td class="num">(86)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">175<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(169)<span></span>
</td>
<td class="nump">202<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis=us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember', window );">Reclassification out of Accumulated Other Comprehensive Income [Member] | Available-for-sale securities [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems', window );"><strong>Reclassification out of Accumulated Other Comprehensive Income [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NonoperatingIncomeExpense', window );">Other income, net</a></td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="nump">33<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_IncomeTaxExpenseBenefit', window );">Provision for income taxes</a></td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="num">(7)<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NetIncomeLoss', window );">Net income</a></td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">0<span></span>
</td>
<td class="nump">26<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis=us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember', window );">Reclassification out of Accumulated Other Comprehensive Income [Member] | Foreign currency contract [Member] | Cash&#160;flow hedges [Member] | Product sales [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems', window );"><strong>Reclassification out of Accumulated Other Comprehensive Income [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="num">(5)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">41<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(24)<span></span>
</td>
<td class="nump">158<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis=us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember', window );">Reclassification out of Accumulated Other Comprehensive Income [Member] | Cross-currency swap contract [Member] | Cash&#160;flow hedges [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems', window );"><strong>Reclassification out of Accumulated Other Comprehensive Income [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NonoperatingIncomeExpense', window );">Other income, net</a></td>
<td class="num">(104)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">183<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(190)<span></span>
</td>
<td class="nump">101<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis=us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember', window );">Reclassification out of Accumulated Other Comprehensive Income [Member] | Cash flow hedges [Member] | Foreign currency contract [Member] | Cash&#160;flow hedges [Member] | Product sales [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems', window );"><strong>Reclassification out of Accumulated Other Comprehensive Income [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="num">(5)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">41<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">(24)<span></span>
</td>
<td class="nump">158<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis=us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember', window );">Reclassification out of Accumulated Other Comprehensive Income [Member] | Cash flow hedges [Member] | Cross-currency swap contract [Member] | Cash&#160;flow hedges [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems', window );"><strong>Reclassification out of Accumulated Other Comprehensive Income [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NonoperatingIncomeExpense', window );">Other income, net</a></td>
<td class="num">$ (104)<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">$ 183<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="num">$ (190)<span></span>
</td>
<td class="nump">$ 101<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of income (loss) from continuing operations before deduction of income tax expense (benefit) and income (loss) attributable to noncontrolling interest, and addition of income (loss) from equity method investments.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8906-108599<br><br>Reference 4: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 31<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8924-108599<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_IncomeTaxExpenseBenefit">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB TOPIC 6.I.7)<br> -URI http://asc.fasb.org/extlink&amp;oid=122134291&amp;loc=d3e330036-122817<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 10<br> -Section 50<br> -Paragraph 10<br> -URI http://asc.fasb.org/extlink&amp;oid=121826272&amp;loc=d3e32672-109319<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -Subparagraph (h)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(h))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 9<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22663-107794<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 740<br> -SubTopic 20<br> -Section 45<br> -Paragraph 2<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123586238&amp;loc=d3e38679-109324<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(9))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22658-107794<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_IncomeTaxExpenseBenefit</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NetIncomeLoss">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-04(22))<br> -URI http://asc.fasb.org/extlink&amp;oid=120399700&amp;loc=SL114874048-224260<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22595-107794<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 220<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-04(18))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400993&amp;loc=SL114874131-224263<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 40<br> -Section 65<br> -Paragraph 1<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123482062&amp;loc=SL123482106-238011<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 50<br> -Paragraph 6<br> -URI http://asc.fasb.org/extlink&amp;oid=124431353&amp;loc=SL124452729-227067<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 8: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03(20))<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br><br>Reference 9: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 28<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3602-108585<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22499-107794<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 12: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 13: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 14: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(i))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 15: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 9<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22663-107794<br><br>Reference 16: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iv))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 17: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(4)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 18: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 50<br> -Paragraph 28<br> -Subparagraph (f)<br> -URI http://asc.fasb.org/extlink&amp;oid=123596393&amp;loc=d3e14064-108612<br><br>Reference 19: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22583-107794<br><br>Reference 20: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 235<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.4-08(g)(1)(ii))<br> -URI http://asc.fasb.org/extlink&amp;oid=120395691&amp;loc=d3e23780-122690<br><br>Reference 21: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 260<br> -SubTopic 10<br> -Section 45<br> -Paragraph 60B<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=125511455&amp;loc=SL5780133-109256<br><br>Reference 22: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 323<br> -SubTopic 10<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=114001798&amp;loc=d3e33918-111571<br><br>Reference 23: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 8<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22658-107794<br><br>Reference 24: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1A<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669619-108580<br><br>Reference 25: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 31<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8924-108599<br><br>Reference 26: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 27: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 250<br> -SubTopic 10<br> -Section 50<br> -Paragraph 11<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124431687&amp;loc=d3e22694-107794<br><br>Reference 28: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 205<br> -SubTopic 20<br> -Section 50<br> -Paragraph 7<br> -URI http://asc.fasb.org/extlink&amp;oid=109222650&amp;loc=SL51721683-107760<br><br>Reference 29: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1B<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669625-108580<br><br>Reference 30: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 31: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1A<br> -Subparagraph (SX 210.13-01(a)(5))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442526-122756<br><br>Reference 32: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(B))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 33: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1B<br> -Subparagraph (SX 210.13-02(a)(4)(iii)(A))<br> -URI http://asc.fasb.org/extlink&amp;oid=124359900&amp;loc=SL124442552-122756<br><br>Reference 34: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8906-108599<br><br>Reference 35: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (c)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NetIncomeLoss</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NonoperatingIncomeExpense">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The aggregate amount of income or expense from ancillary business-related activities (that is to say, excluding major activities considered part of the normal operations of the business).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03.7)<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NonoperatingIncomeExpense</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8906-108599<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 40<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e9031-108599<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 41<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e9038-108599<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130543-203045<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 42<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e9054-108599<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 5<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130545-203045<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 924<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB Topic 11.L)<br> -URI http://asc.fasb.org/extlink&amp;oid=6472922&amp;loc=d3e499488-122856<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=us-gaap_ProductMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=us-gaap_ProductMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis=us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis=us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_ForeignExchangeContractMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=us-gaap_ForeignExchangeContractMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=amgn_CrossCurrencySwapContractsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=amgn_CrossCurrencySwapContractsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>67
<FILENAME>R57.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304135964312">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Fair value measurement (Details) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">$ 12,275<span></span>
</td>
<td class="nump">$ 9,845<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquitySecuritiesFvNi', window );">Equity securities</a></td>
<td class="nump">865<span></span>
</td>
<td class="nump">477<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosure', window );">Total assets</a></td>
<td class="nump">13,415<span></span>
</td>
<td class="nump">10,671<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_BusinessCombinationContingentConsiderationLiability', window );">Contingent consideration obligations</a></td>
<td class="nump">35<span></span>
</td>
<td class="nump">33<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LiabilitiesFairValueDisclosure', window );">Total liabilities</a></td>
<td class="nump">554<span></span>
</td>
<td class="nump">603<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_ForeignExchangeContractMember', window );">Foreign currency contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">127<span></span>
</td>
<td class="nump">28<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">54<span></span>
</td>
<td class="nump">237<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentRiskAxis=amgn_CrossCurrencySwapContractsMember', window );">Cross-currency swap contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">119<span></span>
</td>
<td class="nump">255<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">360<span></span>
</td>
<td class="nump">318<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_InterestRateSwapMember', window );">Interest rate swap contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InterestRateFairValueHedgeAssetAtFairValue', window );">Interest rate swap contracts</a></td>
<td class="nump">29<span></span>
</td>
<td class="nump">66<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue', window );">Interest rate swap contracts</a></td>
<td class="nump">105<span></span>
</td>
<td class="nump">15<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel1Member', window );">Quoted prices in active markets for identical assets (Level 1) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquitySecuritiesFvNi', window );">Equity securities</a></td>
<td class="nump">608<span></span>
</td>
<td class="nump">477<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosure', window );">Total assets</a></td>
<td class="nump">12,882<span></span>
</td>
<td class="nump">10,320<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_BusinessCombinationContingentConsiderationLiability', window );">Contingent consideration obligations</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LiabilitiesFairValueDisclosure', window );">Total liabilities</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel1Member', window );">Quoted prices in active markets for identical assets (Level 1) [Member] | Foreign currency contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel1Member', window );">Quoted prices in active markets for identical assets (Level 1) [Member] | Cross-currency swap contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel1Member', window );">Quoted prices in active markets for identical assets (Level 1) [Member] | Interest rate swap contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InterestRateFairValueHedgeAssetAtFairValue', window );">Interest rate swap contracts</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue', window );">Interest rate swap contracts</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel2Member', window );">Significant other observable inputs (Level 2) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquitySecuritiesFvNi', window );">Equity securities</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosure', window );">Total assets</a></td>
<td class="nump">276<span></span>
</td>
<td class="nump">351<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_BusinessCombinationContingentConsiderationLiability', window );">Contingent consideration obligations</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LiabilitiesFairValueDisclosure', window );">Total liabilities</a></td>
<td class="nump">519<span></span>
</td>
<td class="nump">570<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel2Member', window );">Significant other observable inputs (Level 2) [Member] | Foreign currency contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">127<span></span>
</td>
<td class="nump">28<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">54<span></span>
</td>
<td class="nump">237<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel2Member', window );">Significant other observable inputs (Level 2) [Member] | Cross-currency swap contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">119<span></span>
</td>
<td class="nump">255<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">360<span></span>
</td>
<td class="nump">318<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel2Member', window );">Significant other observable inputs (Level 2) [Member] | Interest rate swap contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InterestRateFairValueHedgeAssetAtFairValue', window );">Interest rate swap contracts</a></td>
<td class="nump">29<span></span>
</td>
<td class="nump">66<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue', window );">Interest rate swap contracts</a></td>
<td class="nump">105<span></span>
</td>
<td class="nump">15<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel3Member', window );">Significant unobservable inputs (Level 3) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_EquitySecuritiesFvNi', window );">Equity securities</a></td>
<td class="nump">257<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rou">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosure', window );">Total assets</a></td>
<td class="nump">257<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_BusinessCombinationContingentConsiderationLiability', window );">Contingent consideration obligations</a></td>
<td class="nump">35<span></span>
</td>
<td class="nump">33<span></span>
</td>
</tr>
<tr class="reu">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LiabilitiesFairValueDisclosure', window );">Total liabilities</a></td>
<td class="nump">35<span></span>
</td>
<td class="nump">33<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel3Member', window );">Significant unobservable inputs (Level 3) [Member] | Foreign currency contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel3Member', window );">Significant unobservable inputs (Level 3) [Member] | Cross-currency swap contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure', window );">Foreign currency and cross-currency swap contracts</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel3Member', window );">Significant unobservable inputs (Level 3) [Member] | Interest rate swap contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeAssetsFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InterestRateFairValueHedgeAssetAtFairValue', window );">Interest rate swap contracts</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract', window );"><strong>Derivatives:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue', window );">Interest rate swap contracts</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_USTreasurySecuritiesMember', window );">U.S. Treasury notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">51<span></span>
</td>
<td class="nump">130<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_USTreasurySecuritiesMember', window );">U.S. Treasury notes [Member] | Quoted prices in active markets for identical assets (Level 1) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">51<span></span>
</td>
<td class="nump">130<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_USTreasurySecuritiesMember', window );">U.S. Treasury notes [Member] | Significant other observable inputs (Level 2) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_USTreasurySecuritiesMember', window );">U.S. Treasury notes [Member] | Significant unobservable inputs (Level 3) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_USTreasuryBillSecuritiesMember', window );">U.S. Treasury bills [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">3,900<span></span>
</td>
<td class="nump">4,948<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_USTreasuryBillSecuritiesMember', window );">U.S. Treasury bills [Member] | Quoted prices in active markets for identical assets (Level 1) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">3,900<span></span>
</td>
<td class="nump">4,948<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_USTreasuryBillSecuritiesMember', window );">U.S. Treasury bills [Member] | Significant other observable inputs (Level 2) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_USTreasuryBillSecuritiesMember', window );">U.S. Treasury bills [Member] | Significant unobservable inputs (Level 3) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_MoneyMarketFundsMember', window );">Money market mutual funds [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">8,323<span></span>
</td>
<td class="nump">4,765<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_MoneyMarketFundsMember', window );">Money market mutual funds [Member] | Quoted prices in active markets for identical assets (Level 1) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">8,323<span></span>
</td>
<td class="nump">4,765<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_MoneyMarketFundsMember', window );">Money market mutual funds [Member] | Significant other observable inputs (Level 2) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=us-gaap_MoneyMarketFundsMember', window );">Money market mutual funds [Member] | Significant unobservable inputs (Level 3) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=amgn_OtherShortTermInterestBearingSecuritiesMember', window );">Other short-term interest-bearing securities [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">1<span></span>
</td>
<td class="nump">2<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=amgn_OtherShortTermInterestBearingSecuritiesMember', window );">Other short-term interest-bearing securities [Member] | Quoted prices in active markets for identical assets (Level 1) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">0<span></span>
</td>
<td class="nump">0<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=amgn_OtherShortTermInterestBearingSecuritiesMember', window );">Other short-term interest-bearing securities [Member] | Significant other observable inputs (Level 2) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">1<span></span>
</td>
<td class="nump">2<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FinancialInstrumentAxis=amgn_OtherShortTermInterestBearingSecuritiesMember', window );">Other short-term interest-bearing securities [Member] | Significant unobservable inputs (Level 3) [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AssetsFairValueDisclosureAbstract', window );"><strong>Assets:</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities', window );">Interest-bearing securities</a></td>
<td class="nump">$ 0<span></span>
</td>
<td class="nump">$ 0<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_DerivativeAssetsFairValueDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Derivative assets.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_DerivativeAssetsFairValueDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Derivative financial instruments liabilities fair value disclosure.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AssetsFairValueDisclosure">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fair value portion of probable future economic benefits obtained or controlled by an entity as a result of past transactions or events.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 820<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123874694&amp;loc=d3e19207-110258<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AssetsFairValueDisclosure</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AssetsFairValueDisclosureAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AssetsFairValueDisclosureAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_AvailableForSaleSecuritiesDebtSecurities">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03(6))<br> -URI http://asc.fasb.org/extlink&amp;oid=120398452&amp;loc=d3e534808-122878<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 326<br> -SubTopic 30<br> -Section 45<br> -Paragraph 1<br> -URI http://asc.fasb.org/extlink&amp;oid=124258926&amp;loc=SL82898722-210454<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=124260329&amp;loc=d3e26610-111562<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 320<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (aa)<br> -URI http://asc.fasb.org/extlink&amp;oid=123581744&amp;loc=d3e27161-111563<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_AvailableForSaleSecuritiesDebtSecurities</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_BusinessCombinationContingentConsiderationLiability">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of liability recognized arising from contingent consideration in a business combination.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 805<br> -SubTopic 30<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (c)(1)<br> -URI http://asc.fasb.org/extlink&amp;oid=120321790&amp;loc=d3e6927-128479<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 805<br> -SubTopic 30<br> -Section 35<br> -Paragraph 1<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=116859824&amp;loc=d3e6819-128478<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 805<br> -SubTopic 30<br> -Section 25<br> -Paragraph 6<br> -URI http://asc.fasb.org/extlink&amp;oid=6911189&amp;loc=d3e6408-128476<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_BusinessCombinationContingentConsiderationLiability</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_EquitySecuritiesFvNi">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of investment in equity security measured at fair value with change in fair value recognized in net income (FV-NI), classified as current.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 825<br> -SubTopic 10<br> -Section 45<br> -Paragraph 1A<br> -URI http://asc.fasb.org/extlink&amp;oid=123594786&amp;loc=SL75136599-209740<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_EquitySecuritiesFvNi</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fair value portion of asset contracts related to the exchange of different currencies, including, but not limited to, foreign currency options, forward contracts, and swaps.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ForeignCurrencyContractAssetFairValueDisclosure</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fair value portion of liability contracts related to the exchange of different currencies, including, but not limited to, foreign currency options, forward (delivery or nondelivery) contracts, and swaps entered into.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InterestRateFairValueHedgeAssetAtFairValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fair value as of the balance sheet date of all derivative assets designated as interest rate fair value hedging instruments.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4B<br> -Subparagraph (c)(1)<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL5624163-113959<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InterestRateFairValueHedgeAssetAtFairValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fair value as of the balance sheet date of all derivative liabilities designated as interest rate fair value hedging instruments.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4B<br> -Subparagraph (c)(1)<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL5624163-113959<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LiabilitiesFairValueDisclosure">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fair value of financial and nonfinancial obligations.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 820<br> -SubTopic 10<br> -Section 50<br> -Paragraph 2<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123874694&amp;loc=d3e19207-110258<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LiabilitiesFairValueDisclosure</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_ForeignExchangeContractMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=us-gaap_ForeignExchangeContractMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=amgn_CrossCurrencySwapContractsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=amgn_CrossCurrencySwapContractsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_InterestRateSwapMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=us-gaap_InterestRateSwapMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel1Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel1Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel2Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel2Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel3Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FairValueByFairValueHierarchyLevelAxis=us-gaap_FairValueInputsLevel3Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FinancialInstrumentAxis=us-gaap_USTreasurySecuritiesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FinancialInstrumentAxis=us-gaap_USTreasurySecuritiesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FinancialInstrumentAxis=us-gaap_USTreasuryBillSecuritiesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FinancialInstrumentAxis=us-gaap_USTreasuryBillSecuritiesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FinancialInstrumentAxis=us-gaap_MoneyMarketFundsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FinancialInstrumentAxis=us-gaap_MoneyMarketFundsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FinancialInstrumentAxis=amgn_OtherShortTermInterestBearingSecuritiesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FinancialInstrumentAxis=amgn_OtherShortTermInterestBearingSecuritiesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>68
<FILENAME>R58.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304048558984">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Fair value measurement (Details Textual) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th" colspan="1">9 Months Ended</th>
<th class="th" colspan="1"></th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueDisclosuresAbstract', window );"><strong>Fair Value Disclosures [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge', window );">Length of time hedged in foreign currency contracts (or less)</a></td>
<td class="text">3 years<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NotesPayableFairValueDisclosure', window );">Long-term debt, fair value</a></td>
<td class="nump">$ 42,200<span></span>
</td>
<td class="nump">$ 39,400<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LongTermDebt', window );">Carrying value of debt</a></td>
<td class="nump">$ 37,579<span></span>
</td>
<td class="nump">$ 32,986<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FairValueDisclosuresAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FairValueDisclosuresAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LongTermDebt">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount, after unamortized (discount) premium and debt issuance costs, of long-term debt. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (b)(3)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466204&amp;loc=SL6031897-161870<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69C<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495737-112612<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 944<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.7-03(a)(16))<br> -URI http://asc.fasb.org/extlink&amp;oid=120400017&amp;loc=d3e572229-122910<br><br>Reference 4: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69B<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495735-112612<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 942<br> -SubTopic 210<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.9-03(16))<br> -URI http://asc.fasb.org/extlink&amp;oid=120398452&amp;loc=d3e534808-122878<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1D<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495340-112611<br><br>Reference 7: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02(22))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LongTermDebt</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Maximum period of time the entity is hedging its exposure to variability in future cash flows for forecasted transactions, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Excludes forecasted transactions related to payment of variable interest on existing financial instruments.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 30<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=121549185&amp;loc=d3e80748-113994<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:durationItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NotesPayableFairValueDisclosure">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fair value portion of notes payable.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.19,20,22)<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NotesPayableFairValueDisclosure</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>69
<FILENAME>R59.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051306840">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Derivative instruments (Details Textual) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointFourFivePercentNotesDue2030Member', window );">2.45% notes due 2030 (2.45% 2030 Notes) [Member] | Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossLineItems', window );"><strong>Derivative Instruments, Gain (Loss) [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeNotionalAmount', window );">Derivative, notional amount</a></td>
<td class="nump">$ 1,000<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.45%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointThreeZeroPercentNotesDue2031Member', window );">2.30% notes due 2031 (2.30% 2031 Notes) [Member] | Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossLineItems', window );"><strong>Derivative Instruments, Gain (Loss) [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeNotionalAmount', window );">Derivative, notional amount</a></td>
<td class="nump">$ 500<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DebtInstrumentInterestRateStatedPercentage', window );">Interest rate, stated percentage</a></td>
<td class="nump">2.30%<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgingDesignationAxis=us-gaap_DesignatedAsHedgingInstrumentMember', window );">Derivatives designated as hedging instrument [Member] | Foreign currency forward contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossLineItems', window );"><strong>Derivative Instruments, Gain (Loss) [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeNotionalAmount', window );">Derivative, notional amount</a></td>
<td class="nump">$ 5,700<span></span>
</td>
<td class="nump">$ 5,100<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgingDesignationAxis=us-gaap_DesignatedAsHedgingInstrumentMember', window );">Derivatives designated as hedging instrument [Member] | Interest Rate Swap [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossLineItems', window );"><strong>Derivative Instruments, Gain (Loss) [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeNotionalAmount', window );">Derivative, notional amount</a></td>
<td class="nump">7,400<span></span>
</td>
<td class="nump">5,900<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgingDesignationAxis=us-gaap_DesignatedAsHedgingInstrumentMember', window );">Derivatives designated as hedging instrument [Member] | Interest Rate Swap [Member] | 2030 And 2021 Note Hedges</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossLineItems', window );"><strong>Derivative Instruments, Gain (Loss) [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeNotionalAmount', window );">Derivative, notional amount</a></td>
<td class="nump">1,500<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgingDesignationAxis=us-gaap_NondesignatedMember', window );">Derivatives not designated as hedging instrument [Member] | Foreign currency forward contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossLineItems', window );"><strong>Derivative Instruments, Gain (Loss) [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeNotionalAmount', window );">Derivative, notional amount</a></td>
<td class="nump">$ 700<span></span>
</td>
<td class="nump">$ 1,000<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentInterestRateStatedPercentage">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Contractual interest rate for funds borrowed, under the debt agreement.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1B<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495323-112611<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SX 210.5-02.22(a)(1))<br> -URI http://asc.fasb.org/extlink&amp;oid=120391452&amp;loc=d3e13212-122682<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentInterestRateStatedPercentage</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentsGainLossLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentsGainLossLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeNotionalAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Nominal or face amount used to calculate payment on derivative.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1B<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL5580258-113959<br><br>Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1A<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL5579245-113959<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeNotionalAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointFourFivePercentNotesDue2030Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointFourFivePercentNotesDue2030Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPointThreeZeroPercentNotesDue2031Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPointThreeZeroPercentNotesDue2031Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_HedgingDesignationAxis=us-gaap_DesignatedAsHedgingInstrumentMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_HedgingDesignationAxis=us-gaap_DesignatedAsHedgingInstrumentMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_ForwardContractsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=us-gaap_ForwardContractsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_InterestRateSwapMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=us-gaap_InterestRateSwapMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_DerivativeInstrumentNameAxis=amgn_A2030And2021NoteHedgesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_DerivativeInstrumentNameAxis=amgn_A2030And2021NoteHedgesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_HedgingDesignationAxis=us-gaap_NondesignatedMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_HedgingDesignationAxis=us-gaap_NondesignatedMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>70
<FILENAME>R60.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304050724744">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Derivative instruments (Cross-currency Swaps) (Details) - Cash flow hedge [Member] - Cross-currency swap contracts [Member]<br> &#8364; in Millions, &#163; in Millions, SFr in Millions, $ in Millions</strong></div></th>
<th class="th">
<div>Sep. 30, 2021 </div>
<div>USD ($)</div>
</th>
<th class="th">
<div>Sep. 30, 2021 </div>
<div>EUR (&#8364;)</div>
</th>
<th class="th">
<div>Sep. 30, 2021 </div>
<div>CHF (SFr)</div>
</th>
<th class="th">
<div>Sep. 30, 2021 </div>
<div>GBP (&#163;)</div>
</th>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">1.25% 2022 euro Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeNotionalAmount', window );">Notional amounts</a></td>
<td class="nump">$ 1,388<span></span>
</td>
<td class="nump">&#8364; 1,250<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">0.41% 2023 Swiss franc Bonds [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeNotionalAmount', window );">Notional amounts</a></td>
<td class="nump">704<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">SFr 700<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">2.00% 2026 euro Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeNotionalAmount', window );">Notional amounts</a></td>
<td class="nump">833<span></span>
</td>
<td class="nump">&#8364; 750<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">5.50% 2026 pound sterling Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeNotionalAmount', window );">Notional amounts</a></td>
<td class="nump">747<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">&#163; 475<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">4.00% 2029 pound sterling Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeNotionalAmount', window );">Notional amounts</a></td>
<td class="nump">$ 1,111<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">&#163; 700<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">Euro Member Countries, Euro | 1.25% 2022 euro Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFixedInterestRate', window );">Interest rates</a></td>
<td class="nump">1.30%<span></span>
</td>
<td class="nump">1.30%<span></span>
</td>
<td class="nump">1.30%<span></span>
</td>
<td class="nump">1.30%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">Euro Member Countries, Euro | 2.00% 2026 euro Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFixedInterestRate', window );">Interest rates</a></td>
<td class="nump">2.00%<span></span>
</td>
<td class="nump">2.00%<span></span>
</td>
<td class="nump">2.00%<span></span>
</td>
<td class="nump">2.00%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">Switzerland, Francs | 0.41% 2023 Swiss franc Bonds [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFixedInterestRate', window );">Interest rates</a></td>
<td class="nump">0.40%<span></span>
</td>
<td class="nump">0.40%<span></span>
</td>
<td class="nump">0.40%<span></span>
</td>
<td class="nump">0.40%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">United Kingdom, Pounds | 5.50% 2026 pound sterling Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFixedInterestRate', window );">Interest rates</a></td>
<td class="nump">5.50%<span></span>
</td>
<td class="nump">5.50%<span></span>
</td>
<td class="nump">5.50%<span></span>
</td>
<td class="nump">5.50%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">United Kingdom, Pounds | 4.00% 2029 pound sterling Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFixedInterestRate', window );">Interest rates</a></td>
<td class="nump">4.00%<span></span>
</td>
<td class="nump">4.00%<span></span>
</td>
<td class="nump">4.00%<span></span>
</td>
<td class="nump">4.00%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">United States of America, Dollars | 1.25% 2022 euro Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFixedInterestRate', window );">Interest rates</a></td>
<td class="nump">3.20%<span></span>
</td>
<td class="nump">3.20%<span></span>
</td>
<td class="nump">3.20%<span></span>
</td>
<td class="nump">3.20%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">United States of America, Dollars | 0.41% 2023 Swiss franc Bonds [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFixedInterestRate', window );">Interest rates</a></td>
<td class="nump">3.40%<span></span>
</td>
<td class="nump">3.40%<span></span>
</td>
<td class="nump">3.40%<span></span>
</td>
<td class="nump">3.40%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">United States of America, Dollars | 2.00% 2026 euro Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFixedInterestRate', window );">Interest rates</a></td>
<td class="nump">3.90%<span></span>
</td>
<td class="nump">3.90%<span></span>
</td>
<td class="nump">3.90%<span></span>
</td>
<td class="nump">3.90%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">United States of America, Dollars | 5.50% 2026 pound sterling Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFixedInterestRate', window );">Interest rates</a></td>
<td class="nump">6.00%<span></span>
</td>
<td class="nump">6.00%<span></span>
</td>
<td class="nump">6.00%<span></span>
</td>
<td class="nump">6.00%<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">United States of America, Dollars | 4.00% 2029 pound sterling Notes [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFixedInterestRate', window );">Interest rates</a></td>
<td class="nump">4.50%<span></span>
</td>
<td class="nump">4.50%<span></span>
</td>
<td class="nump">4.50%<span></span>
</td>
<td class="nump">4.50%<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeFixedInterestRate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fixed interest rate related to the interest rate derivative.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeFixedInterestRate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dtr-types:percentItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeNotionalAmount">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Nominal or face amount used to calculate payment on derivative.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1B<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL5580258-113959<br><br>Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 1A<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL5579245-113959<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeNotionalAmount</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=amgn_CrossCurrencySwapContractsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=amgn_CrossCurrencySwapContractsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DebtInstrumentAxis=amgn_FourPercentPoundSterlingNotesDue2029Member">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DebtInstrumentAxis=amgn_FourPercentPoundSterlingNotesDue2029Member</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_CurrencyAxis=currency_EUR">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_CurrencyAxis=currency_EUR</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_CurrencyAxis=currency_CHF">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_CurrencyAxis=currency_CHF</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_CurrencyAxis=currency_GBP">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_CurrencyAxis=currency_GBP</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_CurrencyAxis=currency_USD">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_CurrencyAxis=currency_USD</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>71
<FILENAME>R61.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051627592">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Derivative instruments (Effective Portion of Unrealized Gain (Loss)) (Details) - Cash flow hedge [Member] - USD ($)<br> $ in Millions</strong></div></th>
<th class="th" colspan="2">3 Months Ended</th>
<th class="th" colspan="2">9 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossLineItems', window );"><strong>Derivative Instruments, Gain (Loss) [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax', window );">Total unrealized gains (losses)</a></td>
<td class="nump">$ 16<span></span>
</td>
<td class="nump">$ 60<span></span>
</td>
<td class="nump">$ 93<span></span>
</td>
<td class="num">$ (132)<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">Foreign currency contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossLineItems', window );"><strong>Derivative Instruments, Gain (Loss) [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax', window );">Total unrealized gains (losses)</a></td>
<td class="nump">136<span></span>
</td>
<td class="num">(163)<span></span>
</td>
<td class="nump">273<span></span>
</td>
<td class="num">(25)<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember', window );">Cross-currency swap contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossLineItems', window );"><strong>Derivative Instruments, Gain (Loss) [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax', window );">Total unrealized gains (losses)</a></td>
<td class="num">$ (120)<span></span>
</td>
<td class="nump">$ 223<span></span>
</td>
<td class="num">$ (180)<span></span>
</td>
<td class="num">$ (107)<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentsGainLossLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentsGainLossLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount, before tax and after reclassification, of gain (loss) from derivative instrument designated and qualifying cash flow hedge included in assessment of hedge effectiveness.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 10A<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=SL7669646-108580<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section 45<br> -Paragraph 11<br> -URI http://asc.fasb.org/extlink&amp;oid=124509347&amp;loc=d3e637-108580<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_ForeignExchangeContractMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=us-gaap_ForeignExchangeContractMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=amgn_CrossCurrencySwapContractsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=amgn_CrossCurrencySwapContractsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>72
<FILENAME>R62.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051858632">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Derivative instruments (Hedged Liabilities and Cumulative Amount) (Details) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease', window );">Cumulative amounts of fair value hedging adjustments related to the carrying amounts of the hedged liabilities</a></td>
<td class="nump">$ 371<span></span>
</td>
<td class="nump">$ 566<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByLiabilityClassAxis=amgn_LongTermDebtCurrentMaturitiesMember', window );">Current portion of long-term debt [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgedLiabilityFairValueHedge', window );">Hedged Liability, Fair Value Hedge</a></td>
<td class="nump">840<span></span>
</td>
<td class="nump">89<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease', window );">Cumulative amounts of fair value hedging adjustments related to the carrying amounts of the hedged liabilities</a></td>
<td class="nump">90<span></span>
</td>
<td class="nump">89<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_HedgedLiabilityDiscontinuedFairValueHedge', window );">Carrying value with discontinued hedging relationships</a></td>
<td class="nump">87<span></span>
</td>
<td class="nump">89<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease', window );">Hedging adjustments on discontinued hedging relationships</a></td>
<td class="nump">87<span></span>
</td>
<td class="nump">89<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_FairValueByLiabilityClassAxis=us-gaap_LongTermDebtMember', window );">Long-term debt [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLineItems', window );"><strong>Derivative [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgedLiabilityFairValueHedge', window );">Hedged Liability, Fair Value Hedge</a></td>
<td class="nump">6,809<span></span>
</td>
<td class="nump">6,258<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease', window );">Cumulative amounts of fair value hedging adjustments related to the carrying amounts of the hedged liabilities</a></td>
<td class="nump">281<span></span>
</td>
<td class="nump">477<span></span>
</td>
</tr>
<tr class="re">
<td class="pl custom" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_amgn_HedgedLiabilityDiscontinuedFairValueHedge', window );">Carrying value with discontinued hedging relationships</a></td>
<td class="nump">460<span></span>
</td>
<td class="nump">525<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease', window );">Hedging adjustments on discontinued hedging relationships</a></td>
<td class="nump">$ 360<span></span>
</td>
<td class="nump">$ 425<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_amgn_HedgedLiabilityDiscontinuedFairValueHedge">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Hedged Liability, Discontinued Fair Value Hedge</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">amgn_HedgedLiabilityDiscontinuedFairValueHedge</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>amgn_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of cumulative increase (decrease) in fair value of hedged liability in fair value hedge, attributable to hedged risk, remaining after discontinued hedge.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4EE<br> -Subparagraph (d)<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL109999712-113959<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_HedgedLiabilityFairValueHedge">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of liability hedged in fair value hedging relationship.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4EE<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL109999712-113959<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_HedgedLiabilityFairValueHedge</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of cumulative increase (decrease) in fair value of hedged liability in fair value hedge, attributable to hedged risk.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4EE<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL109999712-113959<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FairValueByLiabilityClassAxis=amgn_LongTermDebtCurrentMaturitiesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FairValueByLiabilityClassAxis=amgn_LongTermDebtCurrentMaturitiesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_FairValueByLiabilityClassAxis=us-gaap_LongTermDebtMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_FairValueByLiabilityClassAxis=us-gaap_LongTermDebtMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>73
<FILENAME>R63.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051766168">
<tr>
<th class="tl" colspan="1" rowspan="2"><div style="width: 200px;"><strong>Derivative instruments (Summary of Income and Expense Line Items) (Details) - USD ($)<br> $ in Millions</strong></div></th>
<th class="th" colspan="2">3 Months Ended</th>
<th class="th" colspan="2">9 Months Ended</th>
</tr>
<tr>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Sep. 30, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossLineItems', window );"><strong>Derivative Instruments, Gain (Loss) [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">$ 6,706<span></span>
</td>
<td class="nump">$ 6,423<span></span>
</td>
<td class="nump">$ 19,133<span></span>
</td>
<td class="nump">$ 18,790<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NonoperatingIncomeExpense', window );">Other income, net</a></td>
<td class="nump">73<span></span>
</td>
<td class="nump">55<span></span>
</td>
<td class="nump">97<span></span>
</td>
<td class="nump">69<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_InterestExpenseDebt', window );">Interest expense, net</a></td>
<td class="num">(296)<span></span>
</td>
<td class="num">(302)<span></span>
</td>
<td class="num">(862)<span></span>
</td>
<td class="num">(944)<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_InterestRateSwapMember', window );">Interest rate swap agreements [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossLineItems', window );"><strong>Derivative Instruments, Gain (Loss) [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1', window );">Gains (losses) on fair value hedging relationships, Hedged items</a></td>
<td class="nump">54<span></span>
</td>
<td class="nump">35<span></span>
</td>
<td class="nump">195<span></span>
</td>
<td class="nump">215<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1', window );">Gains (losses) on fair value hedging relationships, Derivatives designated as hedging instruments</a></td>
<td class="num">(31)<span></span>
</td>
<td class="num">(13)<span></span>
</td>
<td class="num">(128)<span></span>
</td>
<td class="num">(150)<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis=us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember', window );">Reclassification out of Accumulated Other Comprehensive Income [Member] | Cash&#160;flow hedges [Member] | Cross-currency swap contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossLineItems', window );"><strong>Derivative Instruments, Gain (Loss) [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_NonoperatingIncomeExpense', window );">Other income, net</a></td>
<td class="num">(104)<span></span>
</td>
<td class="nump">183<span></span>
</td>
<td class="num">(190)<span></span>
</td>
<td class="nump">101<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=us-gaap_ProductMember', window );">Product sales [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossLineItems', window );"><strong>Derivative Instruments, Gain (Loss) [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="nump">6,320<span></span>
</td>
<td class="nump">6,104<span></span>
</td>
<td class="nump">18,026<span></span>
</td>
<td class="nump">17,906<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_ProductOrServiceAxis=us-gaap_ProductMember', window );">Product sales [Member] | Reclassification out of Accumulated Other Comprehensive Income [Member] | Cash&#160;flow hedges [Member] | Foreign currency contracts [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeInstrumentsGainLossLineItems', window );"><strong>Derivative Instruments, Gain (Loss) [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax', window );">Total revenues</a></td>
<td class="num">$ (5)<span></span>
</td>
<td class="nump">$ 41<span></span>
</td>
<td class="num">$ (24)<span></span>
</td>
<td class="nump">$ 158<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of gain (loss) from the increase (decrease) in fair value of derivative and nonderivative instruments designated as fair value hedging instruments recognized in the income statement.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 25<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)(1)<br> -URI http://asc.fasb.org/extlink&amp;oid=121577467&amp;loc=d3e76258-113986<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of the increase (decrease) in fair value of the hedged item in a fair value hedge recognized in the income statement.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 25<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (a)(1)<br> -URI http://asc.fasb.org/extlink&amp;oid=121577467&amp;loc=d3e76258-113986<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentsGainLossLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentsGainLossLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_InterestExpenseDebt">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount of the cost of borrowed funds accounted for as interest expense for debt.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 6<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466204&amp;loc=SL6036836-161870<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03.8)<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br><br>Reference 3: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69F<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495745-112612<br><br>Reference 4: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 55<br> -Paragraph 69E<br> -URI http://asc.fasb.org/extlink&amp;oid=123466577&amp;loc=SL123495743-112612<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 470<br> -SubTopic 20<br> -Section 50<br> -Paragraph 1F<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123466505&amp;loc=SL123495355-112611<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_InterestExpenseDebt</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_NonoperatingIncomeExpense">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The aggregate amount of income or expense from ancillary business-related activities (that is to say, excluding major activities considered part of the normal operations of the business).</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 220<br> -SubTopic 10<br> -Section S99<br> -Paragraph 2<br> -Subparagraph (SX 210.5-03.7)<br> -URI http://asc.fasb.org/extlink&amp;oid=123367319&amp;loc=SL114868664-224227<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_NonoperatingIncomeExpense</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 30<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8906-108599<br><br>Reference 2: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 40<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e9031-108599<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 41<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e9038-108599<br><br>Reference 4: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 5: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 32<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8933-108599<br><br>Reference 6: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130543-203045<br><br>Reference 7: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 8: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 22<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e8736-108599<br><br>Reference 9: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 280<br> -SubTopic 10<br> -Section 50<br> -Paragraph 42<br> -URI http://asc.fasb.org/extlink&amp;oid=123359005&amp;loc=d3e9054-108599<br><br>Reference 10: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 606<br> -SubTopic 10<br> -Section 50<br> -Paragraph 5<br> -URI http://asc.fasb.org/extlink&amp;oid=123351226&amp;loc=SL49130545-203045<br><br>Reference 11: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 924<br> -SubTopic 10<br> -Section S99<br> -Paragraph 1<br> -Subparagraph (SAB Topic 11.L)<br> -URI http://asc.fasb.org/extlink&amp;oid=6472922&amp;loc=d3e499488-122856<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_InterestRateSwapMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=us-gaap_InterestRateSwapMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis=us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis=us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_StatementEquityComponentsAxis=us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=amgn_CrossCurrencySwapContractsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=amgn_CrossCurrencySwapContractsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_ProductOrServiceAxis=us-gaap_ProductMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_ProductOrServiceAxis=us-gaap_ProductMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_ForeignExchangeContractMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=us-gaap_ForeignExchangeContractMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>74
<FILENAME>R64.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304049879864">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Derivative instruments (Fair Value of Derivatives) (Details) - Derivatives designated as hedging instrument [Member] - USD ($)<br> $ in Millions</strong></div></th>
<th class="th"><div>Sep. 30, 2021</div></th>
<th class="th"><div>Dec. 31, 2020</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeAssetFairValueNetAbstract', window );"><strong>Assets</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFairValueOfDerivativeAsset', window );">Total derivative assets, fair value</a></td>
<td class="nump">$ 275<span></span>
</td>
<td class="nump">$ 349<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLiabilityFairValueNetAbstract', window );"><strong>Liabilities</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFairValueOfDerivativeLiability', window );">Total derivative liabilities, fair value</a></td>
<td class="nump">519<span></span>
</td>
<td class="nump">570<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgingDesignationAxis=us-gaap_DesignatedAsHedgingInstrumentMember', window );">Foreign currency contracts [Member] | Other current assets/Other assets [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeAssetFairValueNetAbstract', window );"><strong>Assets</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFairValueOfDerivativeAsset', window );">Total derivative assets, fair value</a></td>
<td class="nump">127<span></span>
</td>
<td class="nump">28<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgingDesignationAxis=us-gaap_DesignatedAsHedgingInstrumentMember', window );">Foreign currency contracts [Member] | Accrued liabilities/Other noncurrent liabilities [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLiabilityFairValueNetAbstract', window );"><strong>Liabilities</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFairValueOfDerivativeLiability', window );">Total derivative liabilities, fair value</a></td>
<td class="nump">54<span></span>
</td>
<td class="nump">237<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgingDesignationAxis=us-gaap_DesignatedAsHedgingInstrumentMember', window );">Cross-currency swap contracts [Member] | Other current assets/Other assets [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeAssetFairValueNetAbstract', window );"><strong>Assets</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFairValueOfDerivativeAsset', window );">Total derivative assets, fair value</a></td>
<td class="nump">119<span></span>
</td>
<td class="nump">255<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgingDesignationAxis=us-gaap_DesignatedAsHedgingInstrumentMember', window );">Cross-currency swap contracts [Member] | Accrued liabilities/Other noncurrent liabilities [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLiabilityFairValueNetAbstract', window );"><strong>Liabilities</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFairValueOfDerivativeLiability', window );">Total derivative liabilities, fair value</a></td>
<td class="nump">360<span></span>
</td>
<td class="nump">318<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgingDesignationAxis=us-gaap_DesignatedAsHedgingInstrumentMember', window );">Interest rate swap contracts [Member] | Other current assets/Other assets [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeAssetFairValueNetAbstract', window );"><strong>Assets</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFairValueOfDerivativeAsset', window );">Total derivative assets, fair value</a></td>
<td class="nump">29<span></span>
</td>
<td class="nump">66<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_HedgingDesignationAxis=us-gaap_DesignatedAsHedgingInstrumentMember', window );">Interest rate swap contracts [Member] | Accrued liabilities/Other noncurrent liabilities [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeLiabilityFairValueNetAbstract', window );"><strong>Liabilities</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_DerivativeFairValueOfDerivativeLiability', window );">Total derivative liabilities, fair value</a></td>
<td class="nump">$ 105<span></span>
</td>
<td class="nump">$ 15<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeAssetFairValueNetAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeAssetFairValueNetAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeFairValueOfDerivativeAsset">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fair value, before effects of master netting arrangements, of a financial asset or other contract with one or more underlyings, notional amount or payment provision or both, and the contract can be net settled by means outside the contract or delivery of an asset. Includes assets elected not to be offset. Excludes assets not subject to a master netting arrangement.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 20<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=51824906&amp;loc=SL20225862-175312<br><br>Reference 2: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 20<br> -Section 55<br> -Paragraph 22<br> -URI http://asc.fasb.org/extlink&amp;oid=99393222&amp;loc=SL20226052-175313<br><br>Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 20<br> -Section 55<br> -Paragraph 7<br> -URI http://asc.fasb.org/extlink&amp;oid=99393222&amp;loc=SL20226000-175313<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 860<br> -SubTopic 20<br> -Section 50<br> -Paragraph 4D<br> -Subparagraph (c)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=121570589&amp;loc=SL51823488-111719<br><br>Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4B<br> -Subparagraph (a),(c)<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL5624163-113959<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeFairValueOfDerivativeAsset</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>debit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeFairValueOfDerivativeLiability">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Fair value, before effects of master netting arrangements, of a financial liability or contract with one or more underlyings, notional amount or payment provision or both, and the contract can be net settled by means outside the contract or delivery of an asset. Includes liabilities elected not to be offset. Excludes liabilities not subject to a master netting arrangement.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 860<br> -SubTopic 20<br> -Section 50<br> -Paragraph 4D<br> -Subparagraph (c)(2)<br> -URI http://asc.fasb.org/extlink&amp;oid=121570589&amp;loc=SL51823488-111719<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 815<br> -SubTopic 10<br> -Section 50<br> -Paragraph 4B<br> -Subparagraph (a),(c)<br> -URI http://asc.fasb.org/extlink&amp;oid=125515794&amp;loc=SL5624163-113959<br><br>Reference 3: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 20<br> -Section 50<br> -Paragraph 3<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=51824906&amp;loc=SL20225862-175312<br><br>Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 20<br> -Section 55<br> -Paragraph 7<br> -URI http://asc.fasb.org/extlink&amp;oid=99393222&amp;loc=SL20226000-175313<br><br>Reference 5: http://www.xbrl.org/2003/role/exampleRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 210<br> -SubTopic 20<br> -Section 55<br> -Paragraph 22<br> -URI http://asc.fasb.org/extlink&amp;oid=99393222&amp;loc=SL20226052-175313<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeFairValueOfDerivativeLiability</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeLiabilityFairValueNetAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- References</a><div><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeLiabilityFairValueNetAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_HedgingDesignationAxis=us-gaap_DesignatedAsHedgingInstrumentMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_HedgingDesignationAxis=us-gaap_DesignatedAsHedgingInstrumentMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_ForeignExchangeContractMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=us-gaap_ForeignExchangeContractMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_BalanceSheetLocationAxis=amgn_OtherCurrentNoncurrentAssetsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_BalanceSheetLocationAxis=amgn_OtherCurrentNoncurrentAssetsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_BalanceSheetLocationAxis=amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_BalanceSheetLocationAxis=amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=amgn_CrossCurrencySwapContractsMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=amgn_CrossCurrencySwapContractsMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_DerivativeInstrumentRiskAxis=us-gaap_InterestRateSwapMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_DerivativeInstrumentRiskAxis=us-gaap_InterestRateSwapMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>75
<FILENAME>R65.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304051243240">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Contingencies and commitments (Details)<br></strong></div></th>
<th class="th">
<div>Oct. 12, 2021 </div>
<div>patent</div>
</th>
<th class="th">
<div>Sep. 28, 2021 </div>
<div>patent</div>
</th>
<th class="th">
<div>Oct. 26, 2021 </div>
<div>claim</div>
</th>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_srt_LitigationCaseAxis=amgn_OtezlaANDAPatentLitigationMember', window );">Otezla ANDA Patent Litigation [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LossContingenciesLineItems', window );"><strong>Loss Contingencies [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_GainContingencyPatentsFoundInfringedUponNumber', window );">Gain Contingency, Patents Found Infringed upon, Number</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">3<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_SubsequentEventTypeAxis=us-gaap_SubsequentEventMember', window );">Subsequent Event [Member] | Novartis Pharma AG</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LossContingenciesLineItems', window );"><strong>Loss Contingencies [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LossContingencyPendingClaimsNumber', window );">Loss Contingency, Pending Claims, Number | claim</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="nump">2<span></span>
</td>
</tr>
<tr class="rh">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_SubsequentEventTypeAxis=us-gaap_SubsequentEventMember', window );">Subsequent Event [Member] | Otezla ANDA Patent Litigation [Member]</a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_LossContingenciesLineItems', window );"><strong>Loss Contingencies [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_GainContingencyPatentsFoundInfringedUponNumber', window );">Gain Contingency, Patents Found Infringed upon, Number</a></td>
<td class="nump">3<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
<td class="text">&#160;<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_GainContingencyPatentsFoundInfringedUponNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Number of entity's patents that another entity was found to have infringed.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_GainContingencyPatentsFoundInfringedUponNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:integerItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LossContingenciesLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LossContingenciesLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_LossContingencyPendingClaimsNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Number of pending claims pertaining to a loss contingency.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 450<br> -SubTopic 20<br> -Section 50<br> -Paragraph 4<br> -Subparagraph (a)<br> -URI http://asc.fasb.org/extlink&amp;oid=121557415&amp;loc=d3e14435-108349<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_LossContingencyPendingClaimsNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:integerItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_LitigationCaseAxis=amgn_OtezlaANDAPatentLitigationMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_LitigationCaseAxis=amgn_OtezlaANDAPatentLitigationMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SubsequentEventTypeAxis=us-gaap_SubsequentEventMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SubsequentEventTypeAxis=us-gaap_SubsequentEventMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_srt_LitigationCaseAxis=amgn_NovartisPharmaAGMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">srt_LitigationCaseAxis=amgn_NovartisPharmaAGMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>76
<FILENAME>R66.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140304047116600">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Subsequent events (Details) - Teneobio Inc. - Subsequent Event [Member]<br> $ in Millions</strong></div></th>
<th class="th">
<div>Oct. 19, 2021 </div>
<div>USD ($)</div>
</th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_SubsequentEventLineItems', window );"><strong>Subsequent Event [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_PaymentsToAcquireBusinessesGross', window );">Cash paid</a></td>
<td class="nump">$ 900<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh', window );">Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, High</a></td>
<td class="nump">$ 1,600<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>For contingent consideration arrangements recognized in connection with a business combination, this element represents an estimate of the high-end of the potential range (undiscounted) of the consideration which may be paid.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 805<br> -SubTopic 30<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (c)(3)<br> -URI http://asc.fasb.org/extlink&amp;oid=120321790&amp;loc=d3e6927-128479<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>instant</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_PaymentsToAcquireBusinessesGross">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The cash outflow associated with the acquisition of business during the period. The cash portion only of the acquisition price.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/disclosureRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 805<br> -SubTopic 30<br> -Section 50<br> -Paragraph 1<br> -Subparagraph (b)(1)<br> -URI http://asc.fasb.org/extlink&amp;oid=120321790&amp;loc=d3e6927-128479<br><br>Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef<br> -Publisher FASB<br> -Name Accounting Standards Codification<br> -Topic 230<br> -SubTopic 10<br> -Section 45<br> -Paragraph 13<br> -Subparagraph (b)<br> -URI http://asc.fasb.org/extlink&amp;oid=123570139&amp;loc=d3e3213-108585<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_PaymentsToAcquireBusinessesGross</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:monetaryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>credit</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SubsequentEventLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Detail information of subsequent event by type. User is expected to use existing line items from elsewhere in the taxonomy as the primary line items for this disclosure, which is further associated with dimension and member elements pertaining to a subsequent event.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SubsequentEventLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>us-gaap_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_BusinessAcquisitionAxis=amgn_TeneobioIncMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_BusinessAcquisitionAxis=amgn_TeneobioIncMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_us-gaap_SubsequentEventTypeAxis=us-gaap_SubsequentEventMember">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Details</a><div><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">us-gaap_SubsequentEventTypeAxis=us-gaap_SubsequentEventMember</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td></td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td></td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EXCEL
<SEQUENCE>77
<FILENAME>Financial_Report.xlsx
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
begin 644 Financial_Report.xlsx
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M?!^2!F.,6_0T7X\48JVFL:W&VC$,>8!8\PRA9CC?AT6:&C/5BZPYC0IO0=5
MY3_;U UH]@TT')$%7C&9MC:CY$X*/-S^[PVPPL2.X>V+OP%02P,$%     @
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M8)9WZXPI-CF68DND_AK0]$7NF]P:>A,F>A@72L+;$.S49":>N"1S&#'2)6G
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MA2.K#%_3JE0Y62"5G=M]JTV&XT&Z8+MVN:,B2]!'M><]B'1P_@D,9NLJ/ W
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MH-X_<R[?;NH&^N\[BW\ 4$L#!!0    ( !"A8E-=ZBP>804   ,5   8
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MQ'R2%G[9S8<=O(MKTBQ,<%J86=#I\'O)!R3TOY# "_R6?.;=^!.5G?BB&U]
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MN-EHRZS9UBU1Y/I2\$<@#%K/9BX:VS2C]6Y8;=QXKX3^+]/CU/6*UX5V"BV
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MTOJ4VB "$/\F9W-^,"JZ)\_&N4YZV.76:$K/A8J0A^"@'C L'YJ@.$RJGC\
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M(PH5'JE9P-%MF0LA'O *;<EJY"R"<I&BRBED=^M:Z?(]X(+-#>J@<(#-(%4
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MYQT#);Y_&;5%OT/K(F\8&'S+#!]3EC/>9QOJ=C!+@H(<R*W=#Z2NT27U^?O
M'819UTG"CB74I57U0>-/>=U2/V.7YOIB?.AZ&5WZ:4UZVTJK9&S&GM[*3.(7
M !QL0K7N@.(.ZW9>8[LTW;YN+#[&4D88B)3%OT_K;EK*A.:UL"MU#EEV52BA
MVP#QB]@-%=G"UZY7CDT ()FGK+.?NS&-/O:A.-[[)&_(K^2'!UZ%87W^.N]/
M^]\V9OF3?D>>?QA!M!"VH&I:@G4R^NZ;@?+YQX;\$ETK'_@+%Z-KY+'"DDJ>
M"7"_=!ARW0LKZ'_Q.?L74$L#!!0    ( !"A8E- >A&5[P,  ( (   9
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M@F&5T;$% *Z_#Z3L!*S28!6I9JYV$:LB+A&KRHEEH:2<!!Q<ZE[YY7TX?6-
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MD1WN7L/"FS[>=R;&XQ,27Y>XKFH;%+ _-\;?+4* S07XZ!]02P,$%     @
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M%%A>"2<V:Z-;,EX::/XAN!JT04XJ'Y0[9_!60L]MKH514NTMU8Q0%<+P.G'
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MM9P5^A@@ZSL2_\,@;C!^!M=_ 5!+ P04    "  0H6)36%D,*S0*  !F(@
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MHS@Z0F]<"SHF>N/[!7V_%Y3Q(F7O1+J2Q8J]0@N15@K#WDB39,J46K"_OUK
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M(#2 %DC'J:B^>?$"?OO6.D*:I:5 Q>7J3CA;/T$R5/J&:RMY!M*IY=) E%N
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MQ"-224_ T.#3LM@?7\H6HX"L01EA@BIMI=C3\_>W\/S%<A*1:#OD(),P*\#
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MZ7"H5I4IJBZ+17+)\;548 MS$'NFU4(;?Q\+J.8DQY82W0!&\V84:<ER84@
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MR4A61O 2'Q3HJBB86E^CD*NQ%WE;PE<^SXTE!)/1@LUQBN;;XD'1*FBTI+S
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M;N1YSP"2^>=M]?=!-)FS;Z]WREZS^$P<NVYT0I!9;$>R2ZK,_Y-H,G;L#3M
M\M>JQ*99& A](]!E-9)F$H71LU(R:$O)X$1*=FM0=VPLM#XUT^#96>F,3R3W
M^"DL3=YX9["DPWHJ0.%A9E+SU9L3OP75G/AP<^)=\]FRFV,_LNN1$_5:ZF[8
MU-VPM2(>PD065?K[2O"_5&A+(:?&E944'N2RS,HEM4U2E%<)C:D7U>9D#=J
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M]E"NC:)=3GIF\99Q!7=,E @Y,ETJI(H;>'G#E@+UJUG?D!,KVD]J@^>5P?"
MP0E\D(59:WA3I)AV]?L47!-A>!_A>?BDP6O<G$+D]R#TP^ )>U&3<>3L14]E
M_-5E?,EU(J1-6L-?9TMM%#7)WT_X&#0^!L['X.=5E1D@2]9T9O](!8E@6EM>
MQ@M6))P)( 8:#:Q(07"VY((;3O'4IY$",Y"US%$C$QB24BE>K&Q#<OW8(3T9
MGT7Z5&]8@G./H*Q1W:&WN%ECRY,^%+DAL0N9;UBQ^_VW<1B,7NMGS0:VJ)#L
M0"8%C0P-+WE!G2\$@5B_FL*G4AHRM%$\(<.T=\U7!<]XPJAOV_2!UF8N"^HJ
M@_D25=-:/2@U!3&%&VDHD3.7R!3.[A@7%@PG- %/-!,(V@;L\IK"E]/K4[A1
MSOX."@I-PPN( WJXZH2O.Q1M=#6H0D)#U)OX?B-V_ZZX!"?<T2&H6QK1>6E*
M"BXKBU3#N!>%T9Y6Q?U(QT2S=RV5.3&H<BH4O5";DR4R5^R'+!K5H$6]^59R
MLVM+#?UQLQ_&(Q@/8[A$Q>^8':Q4"QJ3- 0+L,>)1;*#A":!A53+0SCJT!=*
M:GW2*.@MVSRF%4PZ]/LZ%U#,X"&E<-(FJT.MN_,%^>Z-QR$1X6AHGY0.,:/>
M((CACX>^G1Z=8.>0!S\NCTLS&OH=^J@T S_NT!<D0<=K.YV$-4^1M.W_GUP*
MOG*DWN^TV/ZJ&K5AVVW="3U)C$A*Z7E@>(E)C<+ H=!_3A0&D7\ AG;G,1P.
M>I/!>*\Z%?<P#@>]T3!^1,MR?PF'88O:Q^%@--IW1KS_BL5PW":/:]$PCCOT
M42TZ'+;)'Y'HT[SR76=UAR9M#$?!_T=C&(WVUD?B,1AWZ./P&+?)7T-C9'\_
M0>/(U2RBQ]"/X+$[2[]U*\Q1K=S=5U,<96&J"V+#;:[79]6M\D&\NIM_8&K%
M*5*!&:GZIZ/8 U7==ZN%D1MWQUQ*0S=61Z[I$P&5%:#]3!(FZX5UT'QT+/X%
M4$L#!!0    ( !"A8E,>K%]]VP<  %(?   9    >&PO=V]R:W-H965T<R]S
M:&5E=#,S+GAM;.59;8_;N!'^*X2;*VS L?5JR9O=!78WEV:!WEUPN[G[4!0%
M5Z(M]B31):DXN5_?&>IE)5N6'=\6:5%_D"62PWEF^,QP*%UNA?Q-)8QI\CE+
M<W4U2K3>7,SG*DI81M5,;%@./2LA,ZKA4:[G:B,9C8U0ELX=RUK,,\KST?6E
M:?L@KR]%H5.>LP^2J"++J/QRRU*QO1K9H[KA9[Y.-#;,KR\W=,T>F/ZX^2#A
M:=[,$O.,Y8J+G$BVNAK=V!>W(8XW W[A;*M:]P0M>1+B-WRXCZ]&%@)B*8LT
MSD#A[Q.[8VF*$P&,?U5SCAJ5*-B^KV=_9VP'6YZH8G<B_97'.KD:A2,2LQ4M
M4OVSV+YGE3T^SA>)5)DKV59CK1&)"J5%5@D#@HSGY3_]7/GA% &G$G ,[E*1
M0?F6:GI]*<662!P-L^&-,=5( SB>XZ(\: F]'.3T]5LF^2>*GB$\5UH6X'"M
MR/B1/J5,32[G&I3@T'E437A;3N@<F'!)?A"Y3A3Y/H]9W)6? [@&H5,CO'4&
M)WQ@FQEQK2EQ+,<>F,]M+';-?.YQB^];%M,\)N]9O.;YFMP@5;CF3)&W7$6I
M4(5DY&\W3S <:/3W 11>@\(S*+Q#5D%TQ47*B%B17"!!:4IH)HH:"\\UDTQI
M(JD&'!!^)))"J==1(27+HR]$;>E&]2W0L.;'A)VD$8")HE\IH:8;5D:S[(G)
M9GFF9 M38/=*I!#O0*0]53P''J<I-*K)!8'0@L#)2:/@X^QA1F*0IE*9!6$Q
MP@5 /^[.=-\%?*S?GCG^=PC3(:R0 L=#ZY__%+H+[PVQIXYOP1B7?$=>P9,;
MAL2=.?!DS3S;R+GD8<L5V"9I'I%;D<>*W+U_1P++PD%&,+ \$,-[9V991FS1
MIRX 93#"R(2N"S)+N/=G?BVS 1MBHL""%"E92]L+]PWQ A^'E@J]@"S,1%ZM
M<#DHC&B]2K,]M6T;GF"J 4[[#:?]069]S&%;2/GOL&)KV [(& )'32!U1V*=
MFV9H_$DG0)@[D<$>DF!R-W$8B8P9CB/EXOZ<%#,%3(&EC)%@$54)60''2((D
MZ0V$8;@8"$47<AD("!O\U<5]\]/=_1]#N!\;W5!X3"1C)"NS)\/L27X$R-V6
MY^QE(JFK ]=:LI1B'*B$0Z!B4.+%:MWMA5P$"C"O*62$NX#K&)@R@7\G</')
M\2?D;C\/M 3'MF--B ,A,K9#N!O;5C ACT)#..[Y>%PZ&!78J&UAP65I--FN
M,QE@XJ)AXF)P:7>\M*)<DD\T+5B_F_JX,ZP N9.4R2GE](FGY6Z![#$S0WM4
M9$5J,+R&LH%#9_Q/V,]+IB"1=E"5*5<G0K'.G(8UR$49ETR$ (+X 3;D"AK@
M3HF4QT;G+4TA-3'R@/6 &N#:'97R"_JASI6@NL>>L0T+W]C1'MSCTK9]M1.T
M,'"C'G6ZWX5C9W*B=:F(RB7LV8@@3J*JQ9Z6M#]IT)WAMX8$*DW1"#A3D:]?
M0R;-(+R?-*9K#_D:+I&TU=U?=\<LIJ&U-/^.'V(@A39<O2 @_VC]*O\>4\GS
M*"T@MY!785 OHJ':*U!=/X-8X^5R7;9<)R2&^@6BE.<%.+ _1QS:S(V*/1=-
M05IMF"FFTR^S7=.?L7H0UAVPON-_<[2&72_F\#[F0\^W\[F[ZW.OZ_-O!'@@
MHP=-1@^&Z^7RT(@@6CF$EX4#8F"?-Y@R" H2#BA[L_JP$LSJ9<)$!VAS!*J.
MJ[!]F8Q5*V\GY$$4IADEV6K%<*O$^H>!TU=29.TTBN/VMO-IM;B(YX15.EY1
M]*S@?I'1,^B#%'$1::(H^J0LXDJ[IR1G^KG6KCQ0MIXG598-1SP]KD0F;5]#
M3:F U$?WR0<-?Q7]5W7YB=G:=3"C5U7/<F%*E'"*]3@D^P!;PP6DD,?6>II4
M5B\;(MO?&B\@8DU)*8Y7;&!N2I7B*PXX1:%Q?JP]>XY*[;IM["-6.%TXMO.F
M<S=VO/ZNX8JN,X5M'9@#^Y96N^\OW1)/'*^^*LG.\;-$0]? 7[-,%_51L%QG
MW#?[X?C>@0Y[Z7>*YVZM7@-K5_,'['4/ZH8B.)R<%'36*4%G_;\$'; +5\XW
MWK4<$W3!=&F9LP%64>.EYYT1="45_W,QY]F'N&9JOC\2<7;H'IK;LO][HLWU
M#W0X]@M%F^T>CC8?$L].,=TL>=(V(!;X"@GX#GY.L898*6!\VN1D)&U]8FDA
M[8,9@U_A4 -Q L7C[[0N(,TAYYR#4E6[-;&S<U+:.2B9<@_/CJ=4;%7=4;W&
MJ)&N:P]A_<B?#<639L(J$$)B_09AC-.V7$FVL'H;R@&)V.8UY@TLM(B'JKRP
MJ?+"P0+L7>,LX[NX<XSO.NJD,V)?"3B( +^!7*@-C=C5R.0U^8F-RKKPA:$=
M>QO4>DT-J0D%6BWM W-/L78 0-N[)PSYJO@=3)7E'A15YZ[2G'G5FHN\VX$Y
MS@G(313)HOMNH$>D[0BS^0^GV*\#8MO+,V#@&>Q^/[N>"\(Y!X-M^=6&'G]E
M$G8"3.D^6'XR 7O>HOR/\\\)SZ*?XP8ORC\'2J(S^&>'+\F_Q>(<_IU+/]?#
M>L\/+-*WF\Q;WSDS)M?F:ZX"TV"G+#]Y-JW-!^.;\COI\_#R:_,/5*YQ(TS9
M"D2M6>"/B"R_X)8/6FS,5],GH;7(S&W"*-B# Z!_)82N'U!!\QG]^M]02P,$
M%     @ $*%B4WKN9'*+ @  X@4  !D   !X;"]W;W)K<VAE971S+W-H965T
M,S0N>&UL?53;;MLP#/T5P>A#"Q3Q)4W;%(F!7#9L#QV"!MT>ACTH-FT+E257
MDIMVV,>/DAPW+9($1BS)/(>'I,C)5JHG70$8\EISH:=!94QS%X8ZJZ"F>B ;
M$/BED*JF!K>J#'6C@.8.5/,PB:+KL*9,!.G$G:U4.I&MX4S 2A'=UC55;W/@
M<CL-XF!W\,#*RMB#,)TTM(0UF,=FI7 7]BPYJT%H)@514$R#67RW&%E[9_"3
MP5;OK8F-9"/ED]U\SZ=!9 4!A\Q8!HJO%U@ YY8(93QWG$'OT@+WUSOVKRYV
MC&5#-2PD_\5R4TV#VX#D4-"6FP>Y_09=/$Y@)KEV_V3K;6_& <E:;63=@5%!
MS81_T]<N#WN Y/8((.D R6= ? 0P[ !#%ZA7YL):4D/3B9);HJPULMF%RXU#
M8S1,V"JNC<*O#'$F7?OJ$5D0S4K!"I9183"[F6R%8:(DC>0L8Z#)^1(,95Q?
MD#/"!)DSSK$0>A(:U&'9PJSS.?<^DR,^Q^1>"E-I\D7DD'_$AZB_#R+9!3%/
M3A*NH1F0871)DBB)']=+<GYVH:'$RV8.J%N<)EM"AF2Q(XLZLA,:AWVBAXYV
M>(1V]I[1U2ZCOV<;;13>Y#\G'%SU#JZ<@ZLC#GZT]0:4+22VN*+.4Y<$3?Z1
MX_F8>]Z1X[5=_Y+&D_#E@)11+V5T4@K&VM8MIP9R;"F<+AFCOFE%3F@ME6%_
M_0$^C;)ZS=LE:;B[>F@#SRUKK%P4?G9(LO<?1WN:QX-X_.'7Q^"K[B'7^XA/
M489[;52#*MUTT<35S7=4?]H/L)GKV_#=W$^_>ZI*)C3A4" T&MR@=^4GBM\8
MV;BFW$B#+>Z6%0YA4-8 OQ=2FMW&.NC'>OH?4$L#!!0    ( !"A8E.R6"=&
M(0,  (8*   9    >&PO=V]R:W-H965T<R]S:&5E=#,U+GAM;+U6WV_:,!#^
M5ZQH#ZU$20($2@5(_"A:I79#I=T>ICV8Y"!6DSBU'6CWU^^<A(R6D+)5W0O$
M]GUWW]U]\KFWX>)!^@"*/(5!)/N&KU1\89K2]2&DLLYCB/!DR45(%2[%RI2Q
M .JEH# P&Y;5-D/*(F/02_=F8M#CB0I8!#-!9!*&5#R/(.";OF$;VXU;MO*5
MWC 'O9BN8 [J/IX)7)F%%X^%$$G&(R)@V3>&]L74MC0@M?C&8"-WOHE.9<'Y
M@UY<>7W#THP@ %=I%Q3_UC"&(-">D,=C[M0H8FK@[O?6^S1-'I-94 EC'GQG
MGO+[QKE!/%C2)%"W?/,9\H0<[<_E@4Q_R2:WM0SB)E+Q, <C@Y!%V3]]R@NQ
M [!;!P"-'- X%M#, <UC :T<T#H6X.0 YUA .P>TT]IGQ4HK/:&*#GJ";XC0
MUNA-?Z3M2M%88!9I9<V5P%.&.#48)1)WI"1C'BY81'6[):&11X92HK"'[F/"
M),NV3R:@* OD*3DC]_,).?ET2CX1%I$;%@3:HF<JY*0]FVX>?Y3%;QR(/XQ%
MG=CM&FE8#;L$/JZ&SR&NDZ9U$#XY'FZ5P"_?%WWZS]%-;&/1RT;1RT;JK_E6
M+W>:1GY<XQZY4A#*GQ4QFD6,9AJC=2#&C#[CO:(D43P+(X!LXX*LD2^H&;XD
M8RK][;E75M@L2CN-HF^_]<!N-[L]<[U;OGTCJ[!XP;Y5L&]5LM\R0LV>Q8*[
MNE@")%#A^JGH/5CC91OK%,O$V*H@E.GM38O+?0O;L9Q7F5>Y>9&Y4V3N5&8^
MQ?N;S 0.!7+G@Z Q)(JYV+"KR*U7Z*)=^&]_F/8Z18S._]#>J%.B/>M ?<\+
M;N<?J:Q1YMUYJ8H#G+H%IVXEI[*[O49NP>6KB/U"KE<>LF%+1A<!9/>]+ J7
MDK[&(Q9@,T'J\R0$KT;&B1"(VSVLD:\*55666'<OL5:G/"W;^C.SK+].[/UY
M36 )0EO<T:<<53K/K'WY=%ZG9.Y,9/U"NZ%BQ7""!K!$E%7O8$%$]NC)%HK'
MZ9!><(4C/_WT\:$(0AO@^9)SM5WHN5\\/0>_ 5!+ P04    "  0H6)3<R8L
MJRL)  "7/@  &0   'AL+W=O<FMS:&5E=',O<VAE970S-BYX;6R]6_]OV[@=
M_5<$[S"DP%"+WZDN"=#:VE;L>@V2]6[#83\H,1,+)TN>)"?=87_\)-OQ1Z$^
M8M@*T"^MK3R2(I_X'O5,GC\5Y6_5VI@Z^+K)\NIBMJ[K[;OYO+I;FTU2O2VV
M)F_^<E^4FZ1NOI8/\VI;FF2U+[3)YC0,Y7R3I/GL\GQ_[:J\/"]V=9;FYJH,
MJMUFDY3__6"RXNEB1F;/%Z[3AW7=7IA?GF^3!W-CZB_;J[+Y-C_5LDHW)J_2
M(@]*<W\Q>T_>Q5'4%M@C?D[-4]7Y'+1=N2V*W]HO'U<7L["](Y.9N[JM(FG^
M>S0+DV5M3<U]_.=8Z>S49ENP^_FY]K_L.]]TYC:IS*+(?DE7]?IBIF?!RMPG
MNZR^+I[^9HX=$FU]=T56[?\-G@Y806?!W:ZJB\VQ<','FS0__)]\/0Y$IP E
M P7HL0#U+<".!9A=0 \4X,<"W+<%<2RP[_K\T/?]P"V3.KD\+XNGH&S136WM
MA_WH[TLWXY7F[8-R4Y?-7].F7'UY;1Y-OC-5<+8T=9)FU9O@AR#-@T]IEC5$
M5N?SNFFEQ<[OCC5^.-1(!VIDP:<BK]=5$.<KLT+*+]WE(T?Y>=.[4Q?I<Q<_
M4&>%-V;[-F#AGP(:4O+E9AF<_? &N:V%?RWA<"W+;[^7RCPT,Z]&*HO'WM*+
M\6*G1X+MJV7N1R*X+XM-L&BX*)O9W#R6]3I8[!](4P:_OK^M]M?_[6B0GQKD
M^P;Y0(,_[3:W39W%?=#H7YG4:?X0' >E"OX7#(_/\E"OV-?;2N+C)3F?/R*W
M(DZW(OS['G^M39DG6:?;/S;XX&-M-I6KX_+4FG1V_!]%W=1>'J<@-M4.Y66G
M@U*%\M3'PX.+@#AE+T'+/HA$A%FH&$%I%87XH*I3-Y6SFU=EL=HUCU"59(W0
M_/K)M'2[QD^?*M83L!6=6HM&LA7U'D?):&BQA8!(R"VV^B"B0VH1'R.HABR)
MLT5"L(3P._AJ9N*7&Q_V2,=[R 3\$0KMT9$,'BOH#BD70EL48BA)+-0201&J
MF;!(Q&",43' (J@X8=_'XO7G7[QH!/DF? H:0:.)&$NC0&:&I#:-"(IK:=/8
M1XE&.FT6^R@N]( ;$3 (XG:(.+\M3?;'/Q#%_QR<-2NTW)1W9EN_\6(0!)JH
M*1@$W29Z+(,:FSR1S2""ZDZ=(X-]%&-"V0PB*$7Y (-@&L3M&J\SZ"VL%!2<
MAA/P24'(*1G)Y[&"EWQ*:_FQ0%$VZTL$Q:BR?#;&4))$.)\4/(2Z/<2+3T^)
MI2#F]!O6Y-]/*$@Z=2_)/0CMK[WM]<D"P3!;7A&,MJ<F@B'A@$%2L!'JMI'&
M(+,T>69R9?*BVFV26R]II:#@5$[!'$@Y=2^V/9A3_1$/>S.Q#U(AL;GK@RA3
M]@('0X5D0%@I> AU>\BK]/GK*H@YC28@DX&.,_=*_'4RCQ6\6)TP^Y4# 7%E
M+U<1$!'2TMX80S$^L,YA8"#,;2 ^9'J**@,I9W0*-CNYBGM%[L$FZT\594]-
M#-1[W4= V@X.8@0D.\V]["9X!W-[Q^?:_)XEP5FR+<TFS9+*;[7*0+C9%"$-
M PEG8V.:8P4O!C*T%ZL(2+#>+.R#2'?5<B0.08G.C'[94? .YO8.%W/>:LI
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M[%H_/+UJ;,W#?9H]E,VU=..EK0($7$P1V@C0<C$VM!']((63'H5]D!!VIHJ
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M>FCLK<$/!EMU,"8FDI40#V9RDXP=SPB"'&)M&"B^'N$*\MP0H8P_-:?3N#3
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M$#$%D.-;2L6IH29H7I?3_P!02P,$%     @ $*%B4[W;TUIF @  1P4  !D
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MM* >C=H%T/E"*?NR<&V@Z_KI/U!+ P04    "  0H6)30G4ON(8#  "O"P
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M.!^C.=7VI79B9.VN]D(:;!1NN,96#LH&X/Y22O,QL=VB_SGD[U!+ P04
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M;"]W;W)K<VAE971S+W-H965T-#@N>&ULO9C?;^(X$,?_%0OM0U=:FGA, JP
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MBGR"!YU3?EJ/G)+7Y/-\1DY>G(Y<C?Q&BQM67&<E5W"$:P9ABWB#5R3P O\
M?-H,_Q#J%FG[1^&S9O@<,H1[1^'GS?";G#>R7SP%3QO9+YOA[ZEL9+^RB'P%
M]P[ K_\O=#?_9_P[>_9#QM_:L^_!72R6NF*"NF*"0E_[B+XIITH1L21%Z9!O
MMSA/KC4DZGN#]G:MO5UH[S35(QYO62[#&$\7DDFQDC1Y16@4,7-P44YHKF,A
MV2^("$U$GNI#^5CR] H><Q:O)^V.5_U&[OJ C9W:QDZCC6\+3D+7N"/0!0>"
MEP&B]@Q7)$]Q4R&4+ 25:&B&GJS1XGU!DG&:'BKGSE\.!,._'"C3UTKTD:_=
MVM=NHZ\SMF81I)'"HSWD5*(#&7JE8FR2$Y:27.V,'-H4STN"_HYQ?JO?>^S!
MI8W0E8W0M8W0C8W0NT-">S*WS3*/0MZK0]ZS#'E&V3^'>]:S<.W"1NCR":%'
MSO5KY_K-]9TO%)ZR@/5SOC;?;^\A68!LVCL&M>[!,^Q,PUK[\)DK83K\AX#Z
MWI\;C-=H&-[&(:3**I3^SKW(?X9@^G].$3]XQBP_J[0_$4MWYV)H'E5X%JY8
MJ@B')<*\5A_+5Y;OE+*C15;<%1="X]VS:,;XM@-I!'!^*83>=LSULWXM3GX#
M4$L#!!0    ( !"A8E-R1FV$908  /HC   9    >&PO=V]R:W-H965T<R]S
M:&5E=#4U+GAM;+U:;6_;-A#^*X17; TPUR(IRW;F&$CLV.N H$6";A^*?5!L
MVM8JB:Y$Q^U^_:B7F!9YHI0TV9=&DI\[WI&GY^&Q&A]X\B7=,B;0MRB,TXO.
M5HC=>:^7+K<L\M-W?,=B^<N:)Y$OY&VRZ:6[A/FKW"@*>\1QO%[D!W%G,LZ?
M?4PF8[X781"SCPE*]U'D)]^O6,@/%QW<>7QP&VRV(GO0FXQW_H;=,?%I]S&1
M=[VCEU40L3@->(P2MK[H7.+SA9L;Y(@_ W9(3ZY1ELH]YU^RF_>KBXZ31<1"
MMA29"U_^>6!3%H:9)QG'U])IYSAF9GAZ_>A]GB<OD[GW4S;EX5_!2FPO.L,.
M6K&UOP_%+3_\SLJ$^IF_)0_3_%]T*+ #KX.6^U3PJ#26$41!7/SUOY43<6(@
M_< &I#0@NH%;8T!+ ]K6P"T-W+8&_=*@WS8'KS3PVHXP* T&^6(5LYLOS<P7
M_F2<\ -*,K3TEEWDZYM;RQ4)XJP4[T0B?PVDG9C<";[\LN7ABB7I+XA]W0?B
M.WH[Y=&.QRP6*>)K=/EA^OX,O9TQX0=A>H:ZZ-/=#+U]<X;>H"!&-T$8RJI*
MQSTA \K<]I;EX%?%X*1F<(IN>"RV*;J.5VP%V,_M]B.+?4].Q'$VR.-L7!&K
MPSNV>X>H\RLB#L% /%.[^1_[V&H^LYO?^(DTQ[7FU^V#=Z#)_+'<%\\>O;(4
M]%B8-/=':_R]CY>26E.6U5UQ=9856U:+Z/,M#T,DJ>C@)ZN_+8.YQ\'<?#"W
M9K K/_3C)4-^7N_W;!/$<1!OLIL=2P(.U>95X=++76:,_S 9$G<P[CV<%HP)
M&E'J5D$S .0ZHRKHV@1AQ^MKJ'D;5PL Y WH$529POYQ"OO6*92K(6D_EIR5
M)"Q>?D<B\>,T] O!6?TCJ2S*" 6:R<)S_R2>+NUKZ9L8K$WC''#C.5KJ ,;%
M<.;>,7/O"<7#XI6];#PC@B'!>ME (+VV9B;(K*UK$X2=D5$V;8):-+FJS-[@
M.'N#Y]?-YQL6W;/$]HH/C^,,7Y]/1L?!1B_/)R.S- ?Z<DXAD#O4"@,"Z20P
M;P!5\L:.VDXXKT8#I6LK#TP!D$X$,]!176HG.R5L34U6$(\8$OXW!H>/C5$=
M/?A&R,P*J49.5.3D)1FJ]%8M#6^DYP*A#&D#47K!SIM&K.:MMA"86O.>^NGV
MYY^PY_RVEBT7VK+5AJ5M2 6KC0-V7Y]6L!)9;%?99Q$+!D0/$ZRO)X ZV124
MRPF B$?UY6Q 59-7.HOM0OLIEA,<!O^R%=K()AM^"0&1\O1,34R78CU32.V&
M-2DHL<-VM;MER]!/TV =+ U*1(++TLDX!DQL *FOGID)ZA)='2!/M&YQE+SB
MX8^QXQ"J"3U^$X2-A0$<]6NV<%@)-GZ*8C=3)*">A.C9 "#CO9M!*/V]FS>,
M5VUVE5@3NUA?/LB&WK\/67?-DV[JAPRE3"IW(()V/$F4>!+\^CQ)E.*1IRA>
M2YXDI@KI)-D,F35#YE9(-6.E=<2N=6W(L711+4@]0Q.C;U&LD&KX2D>)O0-_
M/C&6CFW;KF;(S JIYJ3$FMC%NHD2B2F31N2-D)D54HU<*2UYT9:6F%II) +(
MJ9Y((V1N':B:JY)D8I?D#V++DE9DI[20_ ^])E':15ZAVR20..G=)@C2]X1M
M/,T;0-4C0B5@U"Y@;4B/FLV@7IS-D)D54HU>:2*U-Y1YY8$AFSU@E^HQ QC]
MC0(P-3I#E;+2%^TE*=#9&:==($CO)$&0OD]J&*Z:\\E1M%U;BQ>WF2&HDCOZ
M/[2-5"D1?86VD0)=W- ;ZFL'H:C.$1!J--3/>"'48&BL<1M?"PC5)S4-'%7*
M2.W*^"/G6Q3J._7S+0!DO@J0HYK3$JJ$D-J%L!69 KVCD0'0A!KM->2HKKVF
M2GBIO0E]_BZ2 IVGT5X#(+.]ACS5M==4:3RU:WR]5@#":F@%)+YZV":F1BM<
M)<^N79Z;-L N<$YKG D (.-, ')4=R;@*GUV[?K\1*DKO7D5)G1TO@11.JO.
M0)3.JM<0:N3H?-DJKD63KV(.>R=?&D0LV>0?D:1HR?>Q*/YO]_CT^*'*9?YY
MAO;\"I]?8^#Y')\OBL]0E/OBJY@;/Y&RE:*0K>50SKN!7.VD^-"DN!%\EW_G
M<,^%X%%^N67^BB490/Z^YEP\WF0#'#_WF?P'4$L#!!0    ( !"A8E,$=W7P
MW 4  #(@   9    >&PO=V]R:W-H965T<R]S:&5E=#4V+GAM;,U:76_;-A3]
M*X17; U0UR+UG3D&$L>I-2QKT*S;0[$'1:9MH9+HBK3= OWQHV1%LDF*5INL
M\TMBR>=>WD->WGL89K@E^4>ZQ)B!SVF2T8O>DK'5^6! HR5.0_J:K'#&OYF3
M/ T9?\P7 [K*<3@KC=)D@ S#&:1AG/5&P_+=73X:DC5+X@S?Y8"NTS3,OUSA
MA&PO>K#W^.)=O%BRXL5@-%R%"WR/V?O57<Z?!K6769SBC,8D SF>7_0NX7E@
MFH5!B?@KQENZ]QD45!X(^5@\!+.+GE%$A!,<L<)%R']M\!@G2>&)Q_&I<MJK
MQRP,]S\_>K\IR7,R#R'%8Y+\'<_8\J+G]< ,S\-UPMZ1[117A.S"7T026OX$
MVPIK]$"TIHRDE3&/((VSW>_P<S41>P;<C]H 509(-+!:#,S*P.QJ8%4&5E<#
MNS*PNQHXE8'3U<"M#-RNL^15!E[7$?S*P"_38;=^Y>)?ARP<#7.R!7F!YMZ*
M#V4&E=9\S>.L2/9[EO-O8V['1O>,1!^7))GAG/X"\*=US+Z E^]PE(24QO,X
M"HN<I(#O$T#FX/+M.#@#+Z\Q"^.$GH$^>']_#5Z^. ,O0)R!VSA)"OAPP'AL
MQ0B#J(KC:A<':HG#!+<D8TL*)MD,SQ3V4[V]K[$?\#FI)P8]3LP5TCJ\QZO7
MP#1> 60@J(AGK#?_;9UIS:_UYK=ASLUAJ_FD>_"&PORF>_ J\S?=@U>93Y\V
M\\%W<S](!+/>(6;ISVSQ)^Z%>BM$T3I=)R'#,_"6+7$.QB3E#6=9=((-!D$6
MD12##[]S?R!@.*7_:**QZFBL,AJK)9H_"0L3WF4V.%MCY3[;V3NE?='J-B/'
M-9SA8+.?/@J0A<Q#T%0&01^: BI0H#S7-VK4 4V[IFEK:>XF-"ZG\!7(,%,Q
MW;FP]T9VA> F,L2V!98RQ'<%BC+$\=7\G)J?H^57)<<#YG(%5SP!"S^KE]21
MQD=0Y#%1@)"X[E,99-FN(="500ZR'35AMR;L:@G?Y603EPJ),SY*V)4BZ",7
M"H05(.B)JZL V:XP*X$"Y!BNFK!7$_:TA/_@0G5'4T70DT:$GF<=AC7VI)UE
M.0+F6L9 QQ)WNSS:KK3N@VX4GCQ#V$]O5" DSKD\G.G[0N"!#+(=JV57^?6<
M^\>2;+:.&*!A@BGX<(O3!YSKJBXT&IEDG$ 7@'NR#3ZQ#U0.#K:QB82]/E&A
MH"$LUE2!XLF!Q'VD@O%6T%(Z(&K((BW9ITY^E0C@*QB'=/GS3] Q?IWS8QY8
MXMFB8Z8T<@&>@EZ C6" >L7P;:VF<G9850U?S!H9A9"4- I7"(IU0.7*;JD#
ML)$/4*\?OJW=0+G!BV)HHL#T+5^D+(,L6R2L<&2W-!O8Z FH%Q3Z=@/EEM[W
MQ"ZA $%7K.TJ3]#Q18X*,6*@%HZ-A(!Z#?%\9>!RPX^OX4."^SP]^D6[ !1'
MZSQF<<=RT,@ Z)U".6A:)-3WR$[*NO*QOWY2XS@*F1Z'! K(W@'C\.#>]&ID
M/./FKYSIN!Z'3(]# @6DW[+O4:,#D%X'Z/<]DANRQ.TH9'H<$B@@J*7MHZ;M
MHQ_5]F]XZXL7&>!;/,=9] 5$)&-YR*5B9VW  =\L+U$C&M IB ;4B ;TU#\S
M($5W%X^D"HP%Q>12J011)"A T/9:\JL1"4@O$IY15N:$TGZ=770;KKXCQ70K
MUP@!Y)Q")C5-&^F;=J=^@U1G>?$4,E&@H"?^T4KIRI?JE<*5 5L2JNGU2'_F
M?]YS"F@I0_]7,6LD!O)/( 7-1@^8>CUPO)B9BM8L%C,%1BIF*C]2,5. 6HN9
MV0@!4R\$?DSN_>>%SFS4@8E.(<OVK@G,IQ>ZRH>C+W0*E%SHE*ZD0J=R)16Z
MP=[]88KS17GY3/G"KC.VNRBIW]87W)?EM:[P_@J>OX&*]U-X'NRNKQOWN]OT
MVS!?Q!D%"9[SH8S7+M\6^>Z">O? R*J\O7P@C)&T_+C$X0SG!8!_/R>$/3X4
M ]3_)C#Z%U!+ P04    "  0H6)36EVN0KD)  !23   &0   'AL+W=O<FMS
M:&5E=',O<VAE970U-RYX;6R]G%]OXS82P+^*8/1A%^C&(JF_BR1 FUQQ!;JX
M;=/M/1SZH-A,(JPLN9*<-$ __%&RXZ%$:D197+_LVLZ0'LY0/\V(,[Y\*<JO
MU1/GM?/W)LNKJ\5376\_+I?5ZHEODNJBV/)<_.6A*#=)+=Z6C\MJ6_)DW0[:
M9$OJNL%RDZ3YXOJR_>QS>7U9[.HLS?GGTJEVFTU2OO[(L^+E:D$6;Q_\ECX^
MU<T'R^O+;?+([WC]9?NY%.^6QUG6Z8;G55KD3LD?KA8_D(\WQ&M'M")_I/RE
MDEX[S5KNB^)K\^;G]=7";53B&5_5S1R)^.^9W_ L:Z82BOQUF'5Q_-)FH/SZ
M;?:?VM6+U=PG%;\ILO^FZ_KI:A$MG#5_2'99_5OQ\F]^6)'?S+<JLJK]UWDY
MR+H+9[6KZF)S&"PTV*3Y_O_D[X,EI '$&QA #P.HZ0!V&,#:A>XU:Y=UF]3)
M]659O#AE(RUF:UZTMFE'B]6D>>/'N[H4?TW%N/KZIR0MG><DVW%GPY-J5W+A
MI-IY=\OK),VJ]\X'Y\O=K?/NN_?.=TZ:.Y_2+!/FKRZ7M?CV9H[EZO!-/^Z_
MB0Y\TQW?7CC,_=ZA+B6:X3?X\%N^$L-).]SM#E^*-1\73H\+I^U\;&"^'ZJ*
MU]5'9"9VG(FU,WD#,_V<U[SD5?WAGB=EFC\Z%5_MRK1.N=9*^\F"=K+F*GN^
M)I2&_N7R63:&*A5''@AU%/6.BGJHHO_Z:Y?6KR/J[:?PI2^.@KYRJHP7AGK=
M_*-N/NJ.6UZFSTES2:,^"8[3!>A2?R_J)'.2UL>Z50;*"@CS2'^=&BDW"(E^
MI>%1M=#&2J/C=!&ZTILBK\6F:R[:E;@NTS4ODQ:0Q7V6/K8OM1:(E+6Q_O(U
M(DR_]OBH;&S@EBQ-[M-L< ?&RM?ZOM=3394)W '=B LH=%'MQ'U!4#\7V"U+
MGJ]>&X/6I;C15,[_/O'-/2__1!Q&).02&SN  ,H(G:9XDJ^=55E4U8?C1]5+
MLH4%:?%-U>U.PY[A-4(T&C \ )0P*P8!T!&<=)8,HG).V8@:&<H&6$@ AL3'
M+VI,5:/-"* D@17; ]Y(> [;A^IF)''?^*H0]0=ND@2 2B(K%@'H$9QZEBRB
M,H\%;M\B&B$R<'U2 "/%P?@6X3CBUL)/V(T4T$BMH)%*41Z.1DQUG96IAF_]
M;:>1"8(!&P,#J14&4F @Q1DX>>4JR8C;#PET0@,7' 7:49QVO^Z*FJ^=;9FN
M>-4D&?O<3J0YY5<1OSDB6W5$7"/BG-4QJ'/>_<*?>>:0]T8;$'!(<1R.IP44
M2$AQ$AK%VU1E6.!&?;.K0H,1-P7042N@HP Z:A+>#4?=5*43H5%$^ZO5B+F,
MNOKU,L 8<VVLEP&M&/DFL?=A6GF!?9"C(EUU@84,9Z%1],U4N"FZ82)=W:0<
M&D^B+3' ^<>9%\4SX"OSK.PFP"##,6@G3#A\">H_3*2K/'"360DC&<"3G2.,
M9"HX%6M@(EWE@:P,3\KM[>;9F0 #>K/8A@L]X*TW,9\^R86'+\%<B(ITE0>V
M>U8B40_HZYTC2??&\8R*=)4'/'OGPO/<7,*3GG9: ;0'@/9P0$^-J+UQ%*,B
M734!Q9X5%'N 8@]'\>1UCT,7%>FJ"=#U<.C>B:LK?1 ;4(1C1?W$2Q&&5;Q\
M3NXS+K;L=@=;DAIE#1Z@T\/1.9XU^$!-'Z>F4=;@CT,1%>GJ!E#TK4#1!RCZ
M)B'I<,;@:]+Q,.BO5!5B_L!3>A^0YUM)R'W@D8\GY*=F"[Z:<RN^QD2ZZDH'
M,CCMC+(%7^67KSRFTPF%0_H!YGS\B.>TRWUV@N #-GTK!ST^ ,[' 6<G@O#5
M8QWU,;]&:.@QOP^4]*T$F &@,CA'@!FHH%0>\VMD!A_S!X#3 ']^</(6GIT5
M!$#H #\G-W4:<#7 0TE+3F,&YP,:H<'S@0 X'EB)*P,@;7".Q#]0*:N>#^B$
MALX' NFP_1NA>&XR$ ", RLP#@#& 0[CJ4%QH"&JLE]5F:&#A0"H&UBA;@C4
M#4\_#=*M/%39J1XLZ(0&KM00^!J:\W67#^Y)9I0-A(#,<&YI40BT#'%:&F4#
MH8YS_5NZ1F@@!@L!A:$5%(: PM DZ!S.!T*57YJ5&B?5(2 NM))4AU(5$)Y4
MGYH-A&KFK!3NZ&0&JF-" %Z( \\H'P@-RHIT,D/: >5"_.AI^J4^.Q.(@)B1
ME8.G", 6X6"S$S%$X\=0J$A7><!C9"6BC("1T3DBR@CCX\$:Q@B- *$1_E3@
MI(T[._Z/@,B1E<+,"$@:X<&B)6^IM9F*MS"1KO) [<A.\:94O7F.G#Y2D:I8
M Q/I*@_0C;X!=.?&_#%@-[:"W1BP&^/8G1KYQN. 146Z:@)@8RN C0&PL5F%
MN_&ZQU&*BG35!)3&.$J_7-Q=.+^7;1O#JY,7-3?;4,#"&&?A>& ? P9C'(,3
MNP9B%6;2(^Z#3755[4-6!>3%>*"*655<SM^^>"L&F,9X09.!?Z1*=9QM4_VC
MJ5I7_*.I:QKR#W'ELG4\(1_QD/5S,>)*I>XN?F(T[A+B2G7NKEDUIZ%3WJ;#
M0(3+]#25*MI=')D3?#+[R01QI<)X%\_83?PAE:F[9B?BQOX8/Q''97J:2E7N
M+H[;KC]$"IN9U=&[4MV[B\>&)J:5BM!=L^>+QJ;59-6QJUI7%?-B;ZB#PY5J
MW%V<EYB!SW*;('*C#\$C0P-7==IYS,)"4U<1->;3N4HCAKA*[A8::1<:<97]
M^X7<"332"F3B&8EV(WU DSTS?M2.R_0TE4@ZTO$SP2?S[Q=R=]!(>Y")/R1$
MCO0&3?;'>"41+M/35,(OP?'[J<CYZX%.SF97[P25'G;YVK 54.(FF5LZ1*1&
M'6+8J6-J8*H>NT2,LKZ--6)>& QU6DGM/H3BZ!PW\WGN'5)#$:%S3W>(U/5#
MJ-7F\;?I1AVFBF$.DX@ZTE5DY##[=Q"IF8C0N4DZD=J!"+6:IK]-AQ(+E>EI
M*K%UI-MHLF?FWT>D5B,RTFMDXA4)FB.-1I.]HF;>JE<PF5YCLP1DA@/Y/^WV
MKYZ*LOX@=-X(0P^J;F1SJ3N)L-FYM]0\1$:ZAZ;:7-,EU'\@HI.A0S:7N\EQ
MIIYD\_/<9Z3V(C+27V3B/8F*(\U%D[UGD*F;]Q$1J9&(,)RXIWK/_DU':E8B
M;';N+W4/D9'VH<G.TI1T*L[2U!\-.4L",<-!;,-9\^]#4DL2\69G_E*/$/'L
M9OZ'Z0+LJD)E]IHNI=][:GYMZU-2/J9YY63\08QQ+YH"F'+_^U7[-W6Q;7\"
MZKZHZV+3OGSBR9J7C8#X^T,AR'=XT_RJU/%GQ*[_#U!+ P04    "  0H6)3
M"H2BXJ$"  !D!@  &0   'AL+W=O<FMS:&5E=',O<VAE970U."YX;6Q]55%/
MVS 0_BNG: \@ 6F3-E#45H)V:).&A.A@#],>W.2:6#AV9SN4_ON=G30KT.8E
ML9W[OOONSG<9;Y1^,06BA;=22#,)"FO7UV%HT@)+9B[4&B5]62E=,DM;G8=F
MK9%E'E2*,.KUDK!D7 ;3L3][T-.QJJS@$A\TF*HLF=[>HE";2= /=@>//"^L
M.PBGXS7+<8'V:?V@:1>V+!DO41JN)&A<38*;_O4L<?;>X)GCQNRMP46R5.K%
M;;YGDZ#G!*' U#H&1J]7G*$0CHAD_&TX@]:E ^ZO=^QW/G:*9<D,SI3XQ3-;
M3(*K #)<L4K81[7YADT\0\>7*F'\$S:U;3(,(*V,564#)@4EE_6;O35YV /T
MCP&B!A!]! R. .(&$/M :V4^K#FS;#K6:@/:61.;6_C<>#1%PZ6KXL)J^LH)
M9Z=WC&MX9:)"*)&92B.5R,+)'"WCPL!/?+,5$Z=P#D^+.9Q\.84OP"7<<R&H
M#&8<6E+AN,*T\7A;>XR.>!S!O9*V,/!59IB]QX>DO@TAVH5P&W42+G!] 7'O
M#*)>U#^@9]8-GV-*\+Z']SKDQ&U&8\\7=V7TV6=TSDTJE$NJ@=\W2V,UW=H_
M'3X&K8^!]S$XXN,'RMP6H%9@J:6@P"S'S)6%VIHNKJ2;HS7*= LIY=IY-7"B
M- @TYO10R;K=Q;!%IDV'\&$K?-@M7,G\W*(NJ=66]@Q6[?4[I*KF2CR7&T>O
MTT%$XVD<ONZ7][-5/!KL6;T3FK1"DTZA,Z;UELN\Z0W*M!-\2&3RV?WE\'+T
M0>0!JVATE7P0&>XU<HDZ]_/-4!$K:>N>;D_;$7KC)T?XW[R>O_=,YUP:*OF*
MH+V+2TJ3KF=:O;%J[<?"4ED:,GY9T&\ M3.@[RNE[&[C'+0_END_4$L#!!0
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M]8(J+T#EQ,C"W2%NI*$;B1LNZ-*(RFZ@]S-)WTTUL=>2^AHZ_@E02P,$%
M  @ $*%B4QO#K(9:!0  P2   !D   !X;"]W;W)K<VAE971S+W-H965T-C N
M>&ULK5I;;]LV&/TKA-<.*9!:XL67=(Z!QE+68,L0Q,CV4.Q!L>E8J"1Z)!VW
MPW[\2%D1I<2B)5EYB'7A.2*/3[[S2<IDQ_@WL:94@N]QE(C+WEK*S2?'$8LU
MC0/19QN:J#,KQN- JEW^Y(@-I\$R!<61@UQWZ,1!F/2FD_38'9].V%9&84+O
M.!#;. [XCRL:L=UE#_9>#MR'3VNI#SC3R29XHG,J'S9W7.TY.<LRC&DB0I8
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M-]<T6%*N!ZCS*Z8LD.WH=\SY?RU,_P=02P,$%     @ $*%B4_H)"^@H P
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MD*9:$\[CKUKIJ+&I!?>?7[3_7#J/SCPR"7.>_I'$:G,YFHQ(#"M6I.J>[SY
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M@$.W;7^F,5NF47/5%4Q$=57;_@3#\\-F2ZUS,1'3%8W'55?.IV73T0V=M3J
ML(M,RL..8!R#V1' L#R8 XQC6%B>_VD\?70\!L.\]:U('^7T48YAV9!Q^<'R
MV#F1/NPCC:(@"$-L1L=CJX,Q-F]A"%^[&N8-&%@>R/2XN<97&Z^0_76 K>F^
M"L%&BE<B-E)\K@&QSQLPHLB^VE@>8&"K@-4.Y+?G@9JR<X( 5A7SAMW!.!)%
M& *U:*_1,$1F)X2/?7VPNR0(HLB. &9W$ 08 G<CCF .P .&!$'Y'MQY'WGU
M>\IK?U4=_0502P,$%     @ $*%B4Y>*NQS     $P(   L   !?<F5L<R\N
M<F5L<YV2N6[#, Q ?\70GC 'T"&(,V7Q%@3Y 5:B#]@2!8I%G;^OVJ5QD L9
M>3T\$MP>:4#M.*2VBZD8_1!2:5K5N %(MB6/:<Z10J[4+!XUA]) 1-MC0[!:
M+#Y +AEFM[UD%J=SI%>(7->=I3W;+T]!;X"O.DQQ0FE(2S,.\,W2?S+W\PPU
M1>5*(Y5;&GC3Y?YVX$G1H2)8%II%R=.B':5_'<?VD-/IKV,BM'I;Z/EQ:%0*
MCMQC)8QQ8K3^-8+)#^Q^ %!+ P04    "  0H6)3J C:9O$$  !V*P  #P
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M _4. KT#]0X"O0/U#@*] _4. KT#]0X"O6/RL9) [T"]@T#O0+V#0.] O8-
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MLAH460V*K 9%5H,BJ_E/6>^=6_]Q_/@L.]OT;_EL_"/:X@502P$"% ,4
M"  0H6)3!T%-8H$   "Q    $               @ $     9&]C4')O<',O
M87!P+GAM;%!+ 0(4 Q0    ( !"A8E,'UN=+[0   "L"   1
M  "  :\   !D;V-0<F]P<R]C;W)E+GAM;%!+ 0(4 Q0    ( !"A8E.97)PC
M$ 8  )PG   3              "  <L!  !X;"]T:&5M92]T:&5M93$N>&UL
M4$L! A0#%     @ $*%B4T".V T&!@  W1L  !@              ("!# @
M 'AL+W=O<FMS:&5E=',O<VAE970Q+GAM;%!+ 0(4 Q0    ( !"A8E/OI_SY
MP0,   $-   8              " @4@.  !X;"]W;W)K<VAE971S+W-H965T
M,BYX;6Q02P$"% ,4    "  0H6)38^1(P]P%  #K&0  &
M@($_$@  >&PO=V]R:W-H965T<R]S:&5E=#,N>&UL4$L! A0#%     @ $*%B
M4UWJ+!YA!0   Q4  !@              ("!41@  'AL+W=O<FMS:&5E=',O
M<VAE970T+GAM;%!+ 0(4 Q0    ( !"A8E/]C4Z@A (  & &   8
M      " @>@=  !X;"]W;W)K<VAE971S+W-H965T-2YX;6Q02P$"% ,4
M"  0H6)39"(:&OD*  "*2@  &               @(&B(   >&PO=V]R:W-H
M965T<R]S:&5E=#8N>&UL4$L! A0#%     @ $*%B4[X#9)JZ @  GP@  !@
M             ("!T2L  'AL+W=O<FMS:&5E=',O<VAE970W+GAM;%!+ 0(4
M Q0    ( !"A8E-]3"I(4 8  "(:   8              " @<$N  !X;"]W
M;W)K<VAE971S+W-H965T."YX;6Q02P$"% ,4    "  0H6)3(C28?V0'  #]
M$0  &               @(%'-0  >&PO=V]R:W-H965T<R]S:&5E=#DN>&UL
M4$L! A0#%     @ $*%B4T!Z$97O P  @ @  !D              ("!X3P
M 'AL+W=O<FMS:&5E=',O<VAE970Q,"YX;6Q02P$"% ,4    "  0H6)3((LS
M934%   ,"P  &0              @($'00  >&PO=V]R:W-H965T<R]S:&5E
M=#$Q+GAM;%!+ 0(4 Q0    ( !"A8E,5P3:IC D  "H9   9
M  " @7-&  !X;"]W;W)K<VAE971S+W-H965T,3(N>&UL4$L! A0#%     @
M$*%B4P5& 9S2 P  V0@  !D              ("!-E   'AL+W=O<FMS:&5E
M=',O<VAE970Q,RYX;6Q02P$"% ,4    "  0H6)3G^/.450#   2!P  &0
M            @($_5   >&PO=V]R:W-H965T<R]S:&5E=#$T+GAM;%!+ 0(4
M Q0    ( !"A8E-860PK- H  &8B   9              " @<I7  !X;"]W
M;W)K<VAE971S+W-H965T,34N>&UL4$L! A0#%     @ $*%B4SR4G6)F @
M(P4  !D              ("!-6(  'AL+W=O<FMS:&5E=',O<VAE970Q-BYX
M;6Q02P$"% ,4    "  0H6)3II(PR%8%  "@#   &0              @('2
M9   >&PO=V]R:W-H965T<R]S:&5E=#$W+GAM;%!+ 0(4 Q0    ( !"A8E.K
M^8*8=@<  . 3   9              " @5]J  !X;"]W;W)K<VAE971S+W-H
M965T,3@N>&UL4$L! A0#%     @ $*%B4^A",>W\!0  LQ$  !D
M     ("!#'(  'AL+W=O<FMS:&5E=',O<VAE970Q.2YX;6Q02P$"% ,4
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M+GAM;%!+ 0(4 Q0    ( !"A8E/\<B6MQ0<  (<4   9              "
M@:JD  !X;"]W;W)K<VAE971S+W-H965T,C0N>&UL4$L! A0#%     @ $*%B
M4S@=0NB-!   M D  !D              ("!IJP  'AL+W=O<FMS:&5E=',O
M<VAE970R-2YX;6Q02P$"% ,4    "  0H6)3D[(JNNT"  !M!@  &0
M        @(%JL0  >&PO=V]R:W-H965T<R]S:&5E=#(V+GAM;%!+ 0(4 Q0
M   ( !"A8E/$0A;I,@0  .\,   9              " @8ZT  !X;"]W;W)K
M<VAE971S+W-H965T,C<N>&UL4$L! A0#%     @ $*%B4V^-,;9L @  ( 4
M !D              ("!][@  'AL+W=O<FMS:&5E=',O<VAE970R."YX;6Q0
M2P$"% ,4    "  0H6)34G]WU]\#  #P"   &0              @(&:NP
M>&PO=V]R:W-H965T<R]S:&5E=#(Y+GAM;%!+ 0(4 Q0    ( !"A8E-TI;Z4
M,P4  $P-   9              " @;"_  !X;"]W;W)K<VAE971S+W-H965T
M,S N>&UL4$L! A0#%     @ $*%B4_T/V-%9!0  %!   !D
M ("!&L4  'AL+W=O<FMS:&5E=',O<VAE970S,2YX;6Q02P$"% ,4    "  0
MH6)3O\K:[S$$  " #   &0              @(&JR@  >&PO=V]R:W-H965T
M<R]S:&5E=#,R+GAM;%!+ 0(4 Q0    ( !"A8E,>K%]]VP<  %(?   9
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M970S-RYX;6Q02P$"% ,4    "  0H6)3+/2GM<P#  !I#@  &0
M    @('CZ0  >&PO=V]R:W-H965T<R]S:&5E=#,X+GAM;%!+ 0(4 Q0    (
M !"A8E.]V]-:9@(  $<%   9              " @>;M  !X;"]W;W)K<VAE
M971S+W-H965T,SDN>&UL4$L! A0#%     @ $*%B4XZ+MU :!   DQ,  !D
M             ("!@_   'AL+W=O<FMS:&5E=',O<VAE970T,"YX;6Q02P$"
M% ,4    "  0H6)3!^:1/\\"  !U"   &0              @('4]   >&PO
M=V]R:W-H965T<R]S:&5E=#0Q+GAM;%!+ 0(4 Q0    ( !"A8E-@D-6/'0(
M (<$   9              " @=KW  !X;"]W;W)K<VAE971S+W-H965T-#(N
M>&UL4$L! A0#%     @ $*%B4UI@M?QT @   08  !D              ("!
M+OH  'AL+W=O<FMS:&5E=',O<VAE970T,RYX;6Q02P$"% ,4    "  0H6)3
M0G4ON(8#  "O"P  &0              @('9_   >&PO=V]R:W-H965T<R]S
M:&5E=#0T+GAM;%!+ 0(4 Q0    ( !"A8E/@,PZRQ@0  /03   9
M      " @98  0!X;"]W;W)K<VAE971S+W-H965T-#4N>&UL4$L! A0#%
M  @ $*%B4Y#P,^EA @  * 8  !D              ("!DP4! 'AL+W=O<FMS
M:&5E=',O<VAE970T-BYX;6Q02P$"% ,4    "  0H6)3Q[QLME4"  !U!0
M&0              @($K" $ >&PO=V]R:W-H965T<R]S:&5E=#0W+GAM;%!+
M 0(4 Q0    ( !"A8E/N]&2B=@0  .D4   9              " @;<* 0!X
M;"]W;W)K<VAE971S+W-H965T-#@N>&UL4$L! A0#%     @ $*%B4ZTM!D=$
M P  ! P  !D              ("!9 \! 'AL+W=O<FMS:&5E=',O<VAE970T
M.2YX;6Q02P$"% ,4    "  0H6)3R4T52$D/  # >   &0
M@('?$@$ >&PO=V]R:W-H965T<R]S:&5E=#4P+GAM;%!+ 0(4 Q0    ( !"A
M8E/QDK+&8@4  ' =   9              " @5\B 0!X;"]W;W)K<VAE971S
M+W-H965T-3$N>&UL4$L! A0#%     @ $*%B4TA)I/4+ P  40H  !D
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M=#4V+GAM;%!+ 0(4 Q0    ( !"A8E-:7:Y"N0D  %),   9
M  " @>4^ 0!X;"]W;W)K<VAE971S+W-H965T-3<N>&UL4$L! A0#%     @
M$*%B4PJ$HN*A @  9 8  !D              ("!U4@! 'AL+W=O<FMS:&5E
M=',O<VAE970U."YX;6Q02P$"% ,4    "  0H6)3Y$:#/7D#  "2#@  &0
M            @(&M2P$ >&PO=V]R:W-H965T<R]S:&5E=#4Y+GAM;%!+ 0(4
M Q0    ( !"A8E,;PZR&6@4  ,$@   9              " @5U/ 0!X;"]W
M;W)K<VAE971S+W-H965T-C N>&UL4$L! A0#%     @ $*%B4_H)"^@H P
MD0H  !D              ("![E0! 'AL+W=O<FMS:&5E=',O<VAE970V,2YX
M;6Q02P$"% ,4    "  0H6)35*;I&UL#  #$#   &0              @(%-
M6 $ >&PO=V]R:W-H965T<R]S:&5E=#8R+GAM;%!+ 0(4 Q0    ( !"A8E,L
M*0-RD@0  /81   9              " @=]; 0!X;"]W;W)K<VAE971S+W-H
M965T-C,N>&UL4$L! A0#%     @ $*%B4YLK?LR/ P  9 \  !D
M     ("!J& ! 'AL+W=O<FMS:&5E=',O<VAE970V-"YX;6Q02P$"% ,4
M"  0H6)333MBL*P"   I"   &0              @(%N9 $ >&PO=V]R:W-H
M965T<R]S:&5E=#8U+GAM;%!+ 0(4 Q0    ( !"A8E.-\F9].P(  *P$   9
M              " @5%G 0!X;"]W;W)K<VAE971S+W-H965T-C8N>&UL4$L!
M A0#%     @ $*%B4[ 5<.%@ P  8A4   T              ( !PVD! 'AL
M+W-T>6QE<RYX;6Q02P$"% ,4    "  0H6)3EXJ[',     3 @  "P
M        @ %.;0$ 7W)E;',O+G)E;'-02P$"% ,4    "  0H6)3J C:9O$$
M  !V*P  #P              @ $W;@$ >&PO=V]R:V)O;VLN>&UL4$L! A0#
M%     @ $*%B4Q[?F5X< @  /2<  !H              ( !57,! 'AL+U]R
M96QS+W=O<FMB;V]K+GAM;"YR96QS4$L! A0#%     @ $*%B4Z5_#G'N 0
MD"8  !,              ( !J74! %M#;VYT96YT7U1Y<&5S72YX;6Q02P4&
2     $H 2@ ]%   R'<!

end
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>78
<FILENAME>Show.js
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
// Edgar(tm) Renderer was created by staff of the U.S. Securities and Exchange Commission.  Data and content created by government employees within the scope of their employment are not subject to domestic copyright protection. 17 U.S.C. 105.
var Show={};Show.LastAR=null,Show.showAR=function(a,r,w){if(Show.LastAR)Show.hideAR();var e=a;while(e&&e.nodeName!='TABLE')e=e.nextSibling;if(!e||e.nodeName!='TABLE'){var ref=((window)?w.document:document).getElementById(r);if(ref){e=ref.cloneNode(!0);
e.removeAttribute('id');a.parentNode.appendChild(e)}}
if(e)e.style.display='block';Show.LastAR=e};Show.hideAR=function(){Show.LastAR.style.display='none'};Show.toggleNext=function(a){var e=a;while(e.nodeName!='DIV')e=e.nextSibling;if(!e.style){}else if(!e.style.display){}else{var d,p_;if(e.style.display=='none'){d='block';p='-'}else{d='none';p='+'}
e.style.display=d;if(a.textContent){a.textContent=p+a.textContent.substring(1)}else{a.innerText=p+a.innerText.substring(1)}}}
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>79
<FILENAME>report.css
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
/* Updated 2009-11-04 */
/* v2.2.0.24 */

/* DefRef Styles */
..report table.authRefData{
	background-color: #def;
	border: 2px solid #2F4497;
	font-size: 1em;
	position: absolute;
}

..report table.authRefData a {
	display: block;
	font-weight: bold;
}

..report table.authRefData p {
	margin-top: 0px;
}

..report table.authRefData .hide {
	background-color: #2F4497;
	padding: 1px 3px 0px 0px;
	text-align: right;
}

..report table.authRefData .hide a:hover {
	background-color: #2F4497;
}

..report table.authRefData .body {
	height: 150px;
	overflow: auto;
	width: 400px;
}

..report table.authRefData table{
	font-size: 1em;
}

/* Report Styles */
..pl a, .pl a:visited {
	color: black;
	text-decoration: none;
}

/* table */
..report {
	background-color: white;
	border: 2px solid #acf;
	clear: both;
	color: black;
	font: normal 8pt Helvetica, Arial, san-serif;
	margin-bottom: 2em;
}

..report hr {
	border: 1px solid #acf;
}

/* Top labels */
..report th {
	background-color: #acf;
	color: black;
	font-weight: bold;
	text-align: center;
}

..report th.void	{
	background-color: transparent;
	color: #000000;
	font: bold 10pt Helvetica, Arial, san-serif;
	text-align: left;
}

..report .pl {
	text-align: left;
	vertical-align: top;
	white-space: normal;
	width: 200px;
	white-space: normal; /* word-wrap: break-word; */
}

..report td.pl a.a {
	cursor: pointer;
	display: block;
	width: 200px;
	overflow: hidden;
}

..report td.pl div.a {
	width: 200px;
}

..report td.pl a:hover {
	background-color: #ffc;
}

/* Header rows... */
..report tr.rh {
	background-color: #acf;
	color: black;
	font-weight: bold;
}

/* Calendars... */
..report .rc {
	background-color: #f0f0f0;
}

/* Even rows... */
..report .re, .report .reu {
	background-color: #def;
}

..report .reu td {
	border-bottom: 1px solid black;
}

/* Odd rows... */
..report .ro, .report .rou {
	background-color: white;
}

..report .rou td {
	border-bottom: 1px solid black;
}

..report .rou table td, .report .reu table td {
	border-bottom: 0px solid black;
}

/* styles for footnote marker */
..report .fn {
	white-space: nowrap;
}

/* styles for numeric types */
..report .num, .report .nump {
	text-align: right;
	white-space: nowrap;
}

..report .nump {
	padding-left: 2em;
}

..report .nump {
	padding: 0px 0.4em 0px 2em;
}

/* styles for text types */
..report .text {
	text-align: left;
	white-space: normal;
}

..report .text .big {
	margin-bottom: 1em;
	width: 17em;
}

..report .text .more {
	display: none;
}

..report .text .note {
	font-style: italic;
	font-weight: bold;
}

..report .text .small {
	width: 10em;
}

..report sup {
	font-style: italic;
}

..report .outerFootnotes {
	font-size: 1em;
}
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>80
<FILENAME>FilingSummary.xml
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<XML>
<?xml version='1.0' encoding='utf-8'?>
<FilingSummary>
  <Version>3.21.2</Version>
  <ProcessingTime/>
  <ReportFormat>html</ReportFormat>
  <ContextCount>491</ContextCount>
  <ElementCount>316</ElementCount>
  <EntityCount>1</EntityCount>
  <FootnotesReported>false</FootnotesReported>
  <SegmentCount>109</SegmentCount>
  <ScenarioCount>0</ScenarioCount>
  <TuplesReported>false</TuplesReported>
  <UnitCount>10</UnitCount>
  <MyReports>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R1.htm</HtmlFileName>
      <LongName>0001001 - Document - Cover Page</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/CoverPage</Role>
      <ShortName>Cover Page</ShortName>
      <MenuCategory>Cover</MenuCategory>
      <Position>1</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R2.htm</HtmlFileName>
      <LongName>1001002 - Statement - Condensed Consolidated Statements of Comprehensive Income</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome</Role>
      <ShortName>Condensed Consolidated Statements of Comprehensive Income</ShortName>
      <MenuCategory>Statements</MenuCategory>
      <Position>2</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R3.htm</HtmlFileName>
      <LongName>1002003 - Statement - Condensed Consolidated Statements of Income</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome</Role>
      <ShortName>Condensed Consolidated Statements of Income</ShortName>
      <MenuCategory>Statements</MenuCategory>
      <Position>3</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R4.htm</HtmlFileName>
      <LongName>1003004 - Statement - Condensed Consolidated Balance Sheets</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/CondensedConsolidatedBalanceSheets</Role>
      <ShortName>Condensed Consolidated Balance Sheets</ShortName>
      <MenuCategory>Statements</MenuCategory>
      <Position>4</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R5.htm</HtmlFileName>
      <LongName>1004005 - Statement - Condensed Consolidated Balance Sheets (Parenthetical)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/CondensedConsolidatedBalanceSheetsParenthetical</Role>
      <ShortName>Condensed Consolidated Balance Sheets (Parenthetical)</ShortName>
      <MenuCategory>Statements</MenuCategory>
      <Position>5</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R6.htm</HtmlFileName>
      <LongName>1005006 - Statement - Condensed Consolidated Statements of Stockholders' Equity</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity</Role>
      <ShortName>Condensed Consolidated Statements of Stockholders' Equity</ShortName>
      <MenuCategory>Statements</MenuCategory>
      <Position>6</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R7.htm</HtmlFileName>
      <LongName>1006007 - Statement - Condensed Consolidated Statements of Stockholders' Equity (Parenthetical)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquityParenthetical</Role>
      <ShortName>Condensed Consolidated Statements of Stockholders' Equity (Parenthetical)</ShortName>
      <MenuCategory>Statements</MenuCategory>
      <Position>7</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R8.htm</HtmlFileName>
      <LongName>1007008 - Statement - Condensed Consolidated Statements of Cash Flows</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows</Role>
      <ShortName>Condensed Consolidated Statements of Cash Flows</ShortName>
      <MenuCategory>Statements</MenuCategory>
      <Position>8</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R9.htm</HtmlFileName>
      <LongName>2101101 - Disclosure - Summary of significant accounting policies</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/Summaryofsignificantaccountingpolicies</Role>
      <ShortName>Summary of significant accounting policies</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>9</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R10.htm</HtmlFileName>
      <LongName>2104102 - Disclosure - Business Combinations and Asset Acquisitions</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitions</Role>
      <ShortName>Business Combinations and Asset Acquisitions</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>10</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R11.htm</HtmlFileName>
      <LongName>2107103 - Disclosure - Revenues</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/Revenues</Role>
      <ShortName>Revenues</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>11</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R12.htm</HtmlFileName>
      <LongName>2110104 - Disclosure - Income taxes</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/Incometaxes</Role>
      <ShortName>Income taxes</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>12</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R13.htm</HtmlFileName>
      <LongName>2112105 - Disclosure - Earnings per share</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/Earningspershare</Role>
      <ShortName>Earnings per share</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>13</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R14.htm</HtmlFileName>
      <LongName>2115106 - Disclosure - Collaborations</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/Collaborations</Role>
      <ShortName>Collaborations</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>14</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R15.htm</HtmlFileName>
      <LongName>2117107 - Disclosure - Investments</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/Investments</Role>
      <ShortName>Investments</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>15</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R16.htm</HtmlFileName>
      <LongName>2125108 - Disclosure - Inventories</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/Inventories</Role>
      <ShortName>Inventories</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>16</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R17.htm</HtmlFileName>
      <LongName>2128109 - Disclosure - Goodwill and other intangible assets</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/Goodwillandotherintangibleassets</Role>
      <ShortName>Goodwill and other intangible assets</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>17</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R18.htm</HtmlFileName>
      <LongName>2133110 - Disclosure - Financing arrangements</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/Financingarrangements</Role>
      <ShortName>Financing arrangements</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>18</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R19.htm</HtmlFileName>
      <LongName>2138111 - Disclosure - Stockholders' equity</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/Stockholdersequity</Role>
      <ShortName>Stockholders' equity</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>19</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R20.htm</HtmlFileName>
      <LongName>2144112 - Disclosure - Fair value measurement</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/Fairvaluemeasurement</Role>
      <ShortName>Fair value measurement</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>20</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R21.htm</HtmlFileName>
      <LongName>2151114 - Disclosure - Derivative instruments</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/Derivativeinstruments</Role>
      <ShortName>Derivative instruments</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>21</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R22.htm</HtmlFileName>
      <LongName>2159115 - Disclosure - Contingencies and commitments</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/Contingenciesandcommitments</Role>
      <ShortName>Contingencies and commitments</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>22</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R23.htm</HtmlFileName>
      <LongName>2161116 - Disclosure - Subsequent events</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/Subsequentevents</Role>
      <ShortName>Subsequent events</ShortName>
      <MenuCategory>Notes</MenuCategory>
      <Position>23</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R24.htm</HtmlFileName>
      <LongName>2202201 - Disclosure - Summary of significant accounting policies (Policies)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesPolicies</Role>
      <ShortName>Summary of significant accounting policies (Policies)</ShortName>
      <MenuCategory>Policies</MenuCategory>
      <Position>24</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R25.htm</HtmlFileName>
      <LongName>2308302 - Disclosure - Revenues (Tables)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/RevenuesTables</Role>
      <ShortName>Revenues (Tables)</ShortName>
      <MenuCategory>Tables</MenuCategory>
      <ParentRole>http://www.amgen.com/role/Revenues</ParentRole>
      <Position>25</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R26.htm</HtmlFileName>
      <LongName>2313303 - Disclosure - Earnings per share (Tables)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/EarningspershareTables</Role>
      <ShortName>Earnings per share (Tables)</ShortName>
      <MenuCategory>Tables</MenuCategory>
      <ParentRole>http://www.amgen.com/role/Earningspershare</ParentRole>
      <Position>26</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R27.htm</HtmlFileName>
      <LongName>2318304 - Disclosure - Investments (Tables)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/InvestmentsTables</Role>
      <ShortName>Investments (Tables)</ShortName>
      <MenuCategory>Tables</MenuCategory>
      <ParentRole>http://www.amgen.com/role/Investments</ParentRole>
      <Position>27</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R28.htm</HtmlFileName>
      <LongName>2326305 - Disclosure - Inventories (Tables)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/InventoriesTables</Role>
      <ShortName>Inventories (Tables)</ShortName>
      <MenuCategory>Tables</MenuCategory>
      <ParentRole>http://www.amgen.com/role/Inventories</ParentRole>
      <Position>28</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R29.htm</HtmlFileName>
      <LongName>2329306 - Disclosure - Goodwill and other intangible assets (Tables)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/GoodwillandotherintangibleassetsTables</Role>
      <ShortName>Goodwill and other intangible assets (Tables)</ShortName>
      <MenuCategory>Tables</MenuCategory>
      <ParentRole>http://www.amgen.com/role/Goodwillandotherintangibleassets</ParentRole>
      <Position>29</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R30.htm</HtmlFileName>
      <LongName>2334307 - Disclosure - Financing arrangements (Tables)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/FinancingarrangementsTables</Role>
      <ShortName>Financing arrangements (Tables)</ShortName>
      <MenuCategory>Tables</MenuCategory>
      <ParentRole>http://www.amgen.com/role/Financingarrangements</ParentRole>
      <Position>30</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R31.htm</HtmlFileName>
      <LongName>2339308 - Disclosure - Stockholders' equity (Tables)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/StockholdersequityTables</Role>
      <ShortName>Stockholders' equity (Tables)</ShortName>
      <MenuCategory>Tables</MenuCategory>
      <ParentRole>http://www.amgen.com/role/Stockholdersequity</ParentRole>
      <Position>31</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R32.htm</HtmlFileName>
      <LongName>2345309 - Disclosure - Fair value measurement (Tables)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/FairvaluemeasurementTables</Role>
      <ShortName>Fair value measurement (Tables)</ShortName>
      <MenuCategory>Tables</MenuCategory>
      <ParentRole>http://www.amgen.com/role/Fairvaluemeasurement</ParentRole>
      <Position>32</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R33.htm</HtmlFileName>
      <LongName>2352311 - Disclosure - Derivative instruments (Tables)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/DerivativeinstrumentsTables</Role>
      <ShortName>Derivative instruments (Tables)</ShortName>
      <MenuCategory>Tables</MenuCategory>
      <ParentRole>http://www.amgen.com/role/Derivativeinstruments</ParentRole>
      <Position>33</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R34.htm</HtmlFileName>
      <LongName>2403401 - Disclosure - Summary of significant accounting policies (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesDetails</Role>
      <ShortName>Summary of significant accounting policies (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesPolicies</ParentRole>
      <Position>34</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R35.htm</HtmlFileName>
      <LongName>2406402 - Disclosure - Business Combinations and Asset Acquisitions (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails</Role>
      <ShortName>Business Combinations and Asset Acquisitions (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitions</ParentRole>
      <Position>35</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R36.htm</HtmlFileName>
      <LongName>2409403 - Disclosure - Revenues (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/RevenuesDetails</Role>
      <ShortName>Revenues (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/RevenuesTables</ParentRole>
      <Position>36</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R37.htm</HtmlFileName>
      <LongName>2411404 - Disclosure - Income taxes (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/IncometaxesDetails</Role>
      <ShortName>Income taxes (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/Incometaxes</ParentRole>
      <Position>37</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R38.htm</HtmlFileName>
      <LongName>2414405 - Disclosure - Earnings per share (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/EarningspershareDetails</Role>
      <ShortName>Earnings per share (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/EarningspershareTables</ParentRole>
      <Position>38</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R39.htm</HtmlFileName>
      <LongName>2416406 - Disclosure - Collaborations (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/CollaborationsDetails</Role>
      <ShortName>Collaborations (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/Collaborations</ParentRole>
      <Position>39</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R40.htm</HtmlFileName>
      <LongName>2419407 - Disclosure - Investments (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/InvestmentsDetails</Role>
      <ShortName>Investments (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/InvestmentsTables</ParentRole>
      <Position>40</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R41.htm</HtmlFileName>
      <LongName>2420408 - Disclosure - Investments (Fair Values by Classification) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails</Role>
      <ShortName>Investments (Fair Values by Classification) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/InvestmentsTables</ParentRole>
      <Position>41</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R42.htm</HtmlFileName>
      <LongName>2421409 - Disclosure - Investments (Available-for-sale Investments) (Details Textual)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/InvestmentsAvailableforsaleInvestmentsDetailsTextual</Role>
      <ShortName>Investments (Available-for-sale Investments) (Details Textual)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/InvestmentsTables</ParentRole>
      <Position>42</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R43.htm</HtmlFileName>
      <LongName>2422410 - Disclosure - Investments (Fair Values by Contractual Maturity) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails</Role>
      <ShortName>Investments (Fair Values by Contractual Maturity) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/InvestmentsTables</ParentRole>
      <Position>43</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R44.htm</HtmlFileName>
      <LongName>2423411 - Disclosure - Investments (Equity Securities) (Details Textual)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual</Role>
      <ShortName>Investments (Equity Securities) (Details Textual)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/InvestmentsTables</ParentRole>
      <Position>44</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R45.htm</HtmlFileName>
      <LongName>2424412 - Disclosure - Investments Investments (Limited Partnership Investments) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails</Role>
      <ShortName>Investments Investments (Limited Partnership Investments) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <Position>45</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R46.htm</HtmlFileName>
      <LongName>2427413 - Disclosure - Inventories (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/InventoriesDetails</Role>
      <ShortName>Inventories (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/InventoriesTables</ParentRole>
      <Position>46</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R47.htm</HtmlFileName>
      <LongName>2430414 - Disclosure - Goodwill and other intangible assets (Goodwill Roll Forward) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/GoodwillandotherintangibleassetsGoodwillRollForwardDetails</Role>
      <ShortName>Goodwill and other intangible assets (Goodwill Roll Forward) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/GoodwillandotherintangibleassetsTables</ParentRole>
      <Position>47</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R48.htm</HtmlFileName>
      <LongName>2431415 - Disclosure - Goodwill and other intangible assets (Identifiable Intangible Assets) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails</Role>
      <ShortName>Goodwill and other intangible assets (Identifiable Intangible Assets) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/GoodwillandotherintangibleassetsTables</ParentRole>
      <Position>48</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R49.htm</HtmlFileName>
      <LongName>2432416 - Disclosure - Goodwill and other intangible assets (Details Textual)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/GoodwillandotherintangibleassetsDetailsTextual</Role>
      <ShortName>Goodwill and other intangible assets (Details Textual)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/GoodwillandotherintangibleassetsTables</ParentRole>
      <Position>49</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R50.htm</HtmlFileName>
      <LongName>2435417 - Disclosure - Financing arrangements (Principal Amounts and Carrying Value of Long-term Borrowings) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails</Role>
      <ShortName>Financing arrangements (Principal Amounts and Carrying Value of Long-term Borrowings) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/FinancingarrangementsTables</ParentRole>
      <Position>50</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R51.htm</HtmlFileName>
      <LongName>2436418 - Disclosure - Financing arrangements (Details Textual)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/FinancingarrangementsDetailsTextual</Role>
      <ShortName>Financing arrangements (Details Textual)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/FinancingarrangementsTables</ParentRole>
      <Position>51</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R52.htm</HtmlFileName>
      <LongName>2437419 - Disclosure - Financing arrangements (interest rate swaps textual interim only) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails</Role>
      <ShortName>Financing arrangements (interest rate swaps textual interim only) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/FinancingarrangementsTables</ParentRole>
      <Position>52</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R53.htm</HtmlFileName>
      <LongName>2440420 - Disclosure - Stockholders' equity (Share Repurchase Program) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/StockholdersequityShareRepurchaseProgramDetails</Role>
      <ShortName>Stockholders' equity (Share Repurchase Program) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/StockholdersequityTables</ParentRole>
      <Position>53</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R54.htm</HtmlFileName>
      <LongName>2441421 - Disclosure - Stockholders' equity (Details Textual) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/StockholdersequityDetailsTextualDetails</Role>
      <ShortName>Stockholders' equity (Details Textual) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/StockholdersequityTables</ParentRole>
      <Position>54</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R55.htm</HtmlFileName>
      <LongName>2442422 - Disclosure - Stockholders' equity (Components of AOCI) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails</Role>
      <ShortName>Stockholders' equity (Components of AOCI) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/StockholdersequityTables</ParentRole>
      <Position>55</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R56.htm</HtmlFileName>
      <LongName>2443423 - Disclosure - Stockholders' equity (Reclassifications out of AOCI) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails</Role>
      <ShortName>Stockholders' equity (Reclassifications out of AOCI) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/StockholdersequityTables</ParentRole>
      <Position>56</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R57.htm</HtmlFileName>
      <LongName>2446424 - Disclosure - Fair value measurement (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/FairvaluemeasurementDetails</Role>
      <ShortName>Fair value measurement (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/FairvaluemeasurementTables</ParentRole>
      <Position>57</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R58.htm</HtmlFileName>
      <LongName>2447425 - Disclosure - Fair value measurement (Details Textual)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/FairvaluemeasurementDetailsTextual</Role>
      <ShortName>Fair value measurement (Details Textual)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/FairvaluemeasurementTables</ParentRole>
      <Position>58</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R59.htm</HtmlFileName>
      <LongName>2453427 - Disclosure - Derivative instruments (Details Textual)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual</Role>
      <ShortName>Derivative instruments (Details Textual)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/DerivativeinstrumentsTables</ParentRole>
      <Position>59</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R60.htm</HtmlFileName>
      <LongName>2454428 - Disclosure - Derivative instruments (Cross-currency Swaps) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails</Role>
      <ShortName>Derivative instruments (Cross-currency Swaps) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/DerivativeinstrumentsTables</ParentRole>
      <Position>60</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R61.htm</HtmlFileName>
      <LongName>2455429 - Disclosure - Derivative instruments (Effective Portion of Unrealized Gain (Loss)) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails</Role>
      <ShortName>Derivative instruments (Effective Portion of Unrealized Gain (Loss)) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/DerivativeinstrumentsTables</ParentRole>
      <Position>61</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R62.htm</HtmlFileName>
      <LongName>2456430 - Disclosure - Derivative instruments (Hedged Liabilities and Cumulative Amount) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails</Role>
      <ShortName>Derivative instruments (Hedged Liabilities and Cumulative Amount) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/DerivativeinstrumentsTables</ParentRole>
      <Position>62</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R63.htm</HtmlFileName>
      <LongName>2457431 - Disclosure - Derivative instruments (Summary of Income and Expense Line Items) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails</Role>
      <ShortName>Derivative instruments (Summary of Income and Expense Line Items) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/DerivativeinstrumentsTables</ParentRole>
      <Position>63</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R64.htm</HtmlFileName>
      <LongName>2458432 - Disclosure - Derivative instruments (Fair Value of Derivatives) (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails</Role>
      <ShortName>Derivative instruments (Fair Value of Derivatives) (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/DerivativeinstrumentsTables</ParentRole>
      <Position>64</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R65.htm</HtmlFileName>
      <LongName>2460433 - Disclosure - Contingencies and commitments (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/ContingenciesandcommitmentsDetails</Role>
      <ShortName>Contingencies and commitments (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/Contingenciesandcommitments</ParentRole>
      <Position>65</Position>
    </Report>
    <Report instance="amgn-20210930.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R66.htm</HtmlFileName>
      <LongName>2462434 - Disclosure - Subsequent events (Details)</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.amgen.com/role/SubsequenteventsDetails</Role>
      <ShortName>Subsequent events (Details)</ShortName>
      <MenuCategory>Details</MenuCategory>
      <ParentRole>http://www.amgen.com/role/Subsequentevents</ParentRole>
      <Position>66</Position>
    </Report>
    <Report>
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <LongName>All Reports</LongName>
      <ReportType>Book</ReportType>
      <ShortName>All Reports</ShortName>
    </Report>
  </MyReports>
  <InputFiles>
    <File doctype="10-Q" original="amgn-20210930.htm">amgn-20210930.htm</File>
    <File>amgn-20210930.xsd</File>
    <File>amgn-20210930_cal.xml</File>
    <File>amgn-20210930_def.xml</File>
    <File>amgn-20210930_lab.xml</File>
    <File>amgn-20210930_pre.xml</File>
    <File>amgn-ex27_202193021xq3.htm</File>
    <File>amgn-ex31_2021930xq3.htm</File>
    <File>amgn-ex32_2021930xq3.htm</File>
  </InputFiles>
  <SupplementalFiles/>
  <BaseTaxonomies>
    <BaseTaxonomy>http://xbrl.sec.gov/dei/2021</BaseTaxonomy>
    <BaseTaxonomy>http://xbrl.sec.gov/country/2021</BaseTaxonomy>
    <BaseTaxonomy>http://fasb.org/srt/2021-01-31</BaseTaxonomy>
    <BaseTaxonomy>http://xbrl.sec.gov/exch/2021</BaseTaxonomy>
    <BaseTaxonomy>http://xbrl.sec.gov/currency/2021</BaseTaxonomy>
    <BaseTaxonomy>http://fasb.org/us-gaap/2021-01-31</BaseTaxonomy>
  </BaseTaxonomies>
  <HasPresentationLinkbase>true</HasPresentationLinkbase>
  <HasCalculationLinkbase>true</HasCalculationLinkbase>
</FilingSummary>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>JSON
<SEQUENCE>83
<FILENAME>MetaLinks.json
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
{
 "instance": {
  "amgn-20210930.htm": {
   "axisCustom": 1,
   "axisStandard": 27,
   "contextCount": 491,
   "dts": {
    "calculationLink": {
     "local": [
      "amgn-20210930_cal.xml"
     ]
    },
    "definitionLink": {
     "local": [
      "amgn-20210930_def.xml"
     ]
    },
    "inline": {
     "local": [
      "amgn-20210930.htm"
     ]
    },
    "labelLink": {
     "local": [
      "amgn-20210930_lab.xml"
     ]
    },
    "presentationLink": {
     "local": [
      "amgn-20210930_pre.xml"
     ]
    },
    "schema": {
     "local": [
      "amgn-20210930.xsd"
     ],
     "remote": [
      "https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd",
      "http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd",
      "http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd",
      "http://www.xbrl.org/2003/xl-2003-12-31.xsd",
      "http://www.xbrl.org/2003/xlink-2003-12-31.xsd",
      "https://www.xbrl.org/dtr/type/2020-01-21/types.xsd",
      "https://www.xbrl.org/2020/extensible-enumerations-2.0.xsd",
      "http://www.xbrl.org/2005/xbrldt-2005.xsd",
      "http://www.xbrl.org/2006/ref-2006-02-27.xsd",
      "https://xbrl.fasb.org/srt/2021/elts/srt-types-2021-01-31.xsd",
      "https://xbrl.sec.gov/country/2021/country-2021.xsd",
      "https://xbrl.fasb.org/srt/2021/elts/srt-roles-2021-01-31.xsd",
      "https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd",
      "https://xbrl.fasb.org/us-gaap/2021/elts/us-types-2021-01-31.xsd",
      "https://xbrl.fasb.org/us-gaap/2021/elts/us-roles-2021-01-31.xsd",
      "https://xbrl.sec.gov/currency/2021/currency-2021.xsd",
      "https://xbrl.sec.gov/dei/2021/dei-2021.xsd",
      "https://xbrl.sec.gov/exch/2021/exch-2021.xsd",
      "http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd",
      "http://www.xbrl.org/lrr/role/net-2009-12-16.xsd",
      "http://www.xbrl.org/lrr/role/reference-2009-12-16.xsd"
     ]
    }
   },
   "elementCount": 553,
   "entityCount": 1,
   "hidden": {
    "http://xbrl.sec.gov/dei/2021": 5,
    "total": 5
   },
   "keyCustom": 23,
   "keyStandard": 293,
   "memberCustom": 64,
   "memberStandard": 44,
   "nsprefix": "amgn",
   "nsuri": "http://www.amgen.com/20210930",
   "report": {
    "R1": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "dei:DocumentType",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "document",
     "isDefault": "true",
     "longName": "0001001 - Document - Cover Page",
     "role": "http://www.amgen.com/role/CoverPage",
     "shortName": "Cover Page",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "dei:DocumentType",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R10": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:BusinessCombinationDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2104102 - Disclosure - Business Combinations and Asset Acquisitions",
     "role": "http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitions",
     "shortName": "Business Combinations and Asset Acquisitions",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:BusinessCombinationDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R11": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:RevenueFromContractWithCustomerTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2107103 - Disclosure - Revenues",
     "role": "http://www.amgen.com/role/Revenues",
     "shortName": "Revenues",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:RevenueFromContractWithCustomerTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R12": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:IncomeTaxDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2110104 - Disclosure - Income taxes",
     "role": "http://www.amgen.com/role/Incometaxes",
     "shortName": "Income taxes",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:IncomeTaxDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R13": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:EarningsPerShareTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2112105 - Disclosure - Earnings per share",
     "role": "http://www.amgen.com/role/Earningspershare",
     "shortName": "Earnings per share",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:EarningsPerShareTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R14": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:CollaborativeArrangementDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2115106 - Disclosure - Collaborations",
     "role": "http://www.amgen.com/role/Collaborations",
     "shortName": "Collaborations",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:CollaborativeArrangementDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R15": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2117107 - Disclosure - Investments",
     "role": "http://www.amgen.com/role/Investments",
     "shortName": "Investments",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R16": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:InventoryDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2125108 - Disclosure - Inventories",
     "role": "http://www.amgen.com/role/Inventories",
     "shortName": "Inventories",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:InventoryDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R17": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:GoodwillAndIntangibleAssetsDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2128109 - Disclosure - Goodwill and other intangible assets",
     "role": "http://www.amgen.com/role/Goodwillandotherintangibleassets",
     "shortName": "Goodwill and other intangible assets",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5e8434e9ddcf4776ae40321c4d1fc17c_D20200101-20200930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:GoodwillAndIntangibleAssetsDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R18": {
     "firstAnchor": {
      "ancestors": [
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DebtDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2133110 - Disclosure - Financing arrangements",
     "role": "http://www.amgen.com/role/Financingarrangements",
     "shortName": "Financing arrangements",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DebtDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R19": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:StockholdersEquityNoteDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2138111 - Disclosure - Stockholders' equity",
     "role": "http://www.amgen.com/role/Stockholdersequity",
     "shortName": "Stockholders' equity",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:StockholdersEquityNoteDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R2": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:NetIncomeLoss",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "statement",
     "isDefault": "false",
     "longName": "1001002 - Statement - Condensed Consolidated Statements of Comprehensive Income",
     "role": "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome",
     "shortName": "Condensed Consolidated Statements of Comprehensive Income",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R20": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:FairValueDisclosuresTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2144112 - Disclosure - Fair value measurement",
     "role": "http://www.amgen.com/role/Fairvaluemeasurement",
     "shortName": "Fair value measurement",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:FairValueDisclosuresTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R21": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2151114 - Disclosure - Derivative instruments",
     "role": "http://www.amgen.com/role/Derivativeinstruments",
     "shortName": "Derivative instruments",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R22": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:CommitmentsAndContingenciesDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2159115 - Disclosure - Contingencies and commitments",
     "role": "http://www.amgen.com/role/Contingenciesandcommitments",
     "shortName": "Contingencies and commitments",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:CommitmentsAndContingenciesDisclosureTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R23": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:SubsequentEventsTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2161116 - Disclosure - Subsequent events",
     "role": "http://www.amgen.com/role/Subsequentevents",
     "shortName": "Subsequent events",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:SubsequentEventsTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R24": {
     "firstAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "amgn:NatureOfOperationsPolicyTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2202201 - Disclosure - Summary of significant accounting policies (Policies)",
     "role": "http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesPolicies",
     "shortName": "Summary of significant accounting policies (Policies)",
     "subGroupType": "policies",
     "uniqueAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "amgn:NatureOfOperationsPolicyTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R25": {
     "firstAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DisaggregationOfRevenueTableTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2308302 - Disclosure - Revenues (Tables)",
     "role": "http://www.amgen.com/role/RevenuesTables",
     "shortName": "Revenues (Tables)",
     "subGroupType": "tables",
     "uniqueAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DisaggregationOfRevenueTableTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R26": {
     "firstAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2313303 - Disclosure - Earnings per share (Tables)",
     "role": "http://www.amgen.com/role/EarningspershareTables",
     "shortName": "Earnings per share (Tables)",
     "subGroupType": "tables",
     "uniqueAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R27": {
     "firstAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DebtSecuritiesAvailableForSaleTableTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2318304 - Disclosure - Investments (Tables)",
     "role": "http://www.amgen.com/role/InvestmentsTables",
     "shortName": "Investments (Tables)",
     "subGroupType": "tables",
     "uniqueAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DebtSecuritiesAvailableForSaleTableTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R28": {
     "firstAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:ScheduleOfInventoryCurrentTableTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2326305 - Disclosure - Inventories (Tables)",
     "role": "http://www.amgen.com/role/InventoriesTables",
     "shortName": "Inventories (Tables)",
     "subGroupType": "tables",
     "uniqueAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:ScheduleOfInventoryCurrentTableTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R29": {
     "firstAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:ScheduleOfGoodwillTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2329306 - Disclosure - Goodwill and other intangible assets (Tables)",
     "role": "http://www.amgen.com/role/GoodwillandotherintangibleassetsTables",
     "shortName": "Goodwill and other intangible assets (Tables)",
     "subGroupType": "tables",
     "uniqueAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:ScheduleOfGoodwillTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R3": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "statement",
     "isDefault": "false",
     "longName": "1002003 - Statement - Condensed Consolidated Statements of Income",
     "role": "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
     "shortName": "Condensed Consolidated Statements of Income",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:CostOfGoodsAndServicesSold",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R30": {
     "firstAnchor": {
      "ancestors": [
       "us-gaap:DebtDisclosureTextBlock",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:ScheduleOfDebtInstrumentsTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2334307 - Disclosure - Financing arrangements (Tables)",
     "role": "http://www.amgen.com/role/FinancingarrangementsTables",
     "shortName": "Financing arrangements (Tables)",
     "subGroupType": "tables",
     "uniqueAnchor": {
      "ancestors": [
       "us-gaap:DebtDisclosureTextBlock",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:ScheduleOfDebtInstrumentsTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R31": {
     "firstAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "amgn:StockRepurchaseProgramTableTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2339308 - Disclosure - Stockholders' equity (Tables)",
     "role": "http://www.amgen.com/role/StockholdersequityTables",
     "shortName": "Stockholders' equity (Tables)",
     "subGroupType": "tables",
     "uniqueAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "amgn:StockRepurchaseProgramTableTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R32": {
     "firstAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2345309 - Disclosure - Fair value measurement (Tables)",
     "role": "http://www.amgen.com/role/FairvaluemeasurementTables",
     "shortName": "Fair value measurement (Tables)",
     "subGroupType": "tables",
     "uniqueAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R33": {
     "firstAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "amgn:ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2352311 - Disclosure - Derivative instruments (Tables)",
     "role": "http://www.amgen.com/role/DerivativeinstrumentsTables",
     "shortName": "Derivative instruments (Tables)",
     "subGroupType": "tables",
     "uniqueAnchor": {
      "ancestors": [
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "amgn:ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R34": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": "INF",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:NumberOfOperatingSegments",
      "reportCount": 1,
      "unitRef": "segment",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2403401 - Disclosure - Summary of significant accounting policies (Details)",
     "role": "http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesDetails",
     "shortName": "Summary of significant accounting policies (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "us-gaap:PropertyPlantAndEquipmentPolicyTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-8",
      "lang": "en-US",
      "name": "us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R35": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:PaymentsToAcquireBusinessesNetOfCashAcquired",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2406402 - Disclosure - Business Combinations and Asset Acquisitions (Details)",
     "role": "http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails",
     "shortName": "Business Combinations and Asset Acquisitions (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i65976c78d95c49118311d26eb3256876_D20210416-20210416",
      "decimals": "-8",
      "lang": "en-US",
      "name": "us-gaap:PaymentsToAcquireBusinessesNetOfCashAcquired",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R36": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": "INF",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:NumberOfOperatingSegments",
      "reportCount": 1,
      "unitRef": "segment",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2409403 - Disclosure - Revenues (Details)",
     "role": "http://www.amgen.com/role/RevenuesDetails",
     "shortName": "Revenues (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:DisaggregationOfRevenueTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "ia3c6be49d4364b1f9f7490f5b324e697_D20210701-20210930",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R37": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "3",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:EffectiveIncomeTaxRateContinuingOperations",
      "reportCount": 1,
      "unique": true,
      "unitRef": "number",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2411404 - Disclosure - Income taxes (Details)",
     "role": "http://www.amgen.com/role/IncometaxesDetails",
     "shortName": "Income taxes (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "3",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:EffectiveIncomeTaxRateContinuingOperations",
      "reportCount": 1,
      "unique": true,
      "unitRef": "number",
      "xsiNil": "false"
     }
    },
    "R38": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:NetIncomeLoss",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2414405 - Disclosure - Earnings per share (Details)",
     "role": "http://www.amgen.com/role/EarningspershareDetails",
     "shortName": "Earnings per share (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:WeightedAverageNumberDilutedSharesOutstandingAdjustment",
      "reportCount": 1,
      "unique": true,
      "unitRef": "shares",
      "xsiNil": "false"
     }
    },
    "R39": {
     "firstAnchor": {
      "ancestors": [
       "ix:continuation",
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "icb5563aa4d0b4e68b3266d16db71f2a1_D20210701-20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "amgn:UpFrontPayment",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2416406 - Disclosure - Collaborations (Details)",
     "role": "http://www.amgen.com/role/CollaborationsDetails",
     "shortName": "Collaborations (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "ix:continuation",
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "icb5563aa4d0b4e68b3266d16db71f2a1_D20210701-20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "amgn:UpFrontPayment",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R4": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:CashAndCashEquivalentsAtCarryingValue",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "statement",
     "isDefault": "false",
     "longName": "1003004 - Statement - Condensed Consolidated Balance Sheets",
     "role": "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets",
     "shortName": "Condensed Consolidated Balance Sheets",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:CashAndCashEquivalentsAtCarryingValue",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R40": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:DebtSecuritiesAvailableForSaleTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2419407 - Disclosure - Investments (Details)",
     "role": "http://www.amgen.com/role/InvestmentsDetails",
     "shortName": "Investments (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:DebtSecuritiesAvailableForSaleTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R41": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2420408 - Disclosure - Investments (Fair Values by Classification) (Details)",
     "role": "http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails",
     "shortName": "Investments (Fair Values by Classification) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "amgn:FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i6a8d71c465184aa38c33193a90315560_I20210930",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:CashAndCashEquivalentsFairValueDisclosure",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R42": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:Cash",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2421409 - Disclosure - Investments (Available-for-sale Investments) (Details Textual)",
     "role": "http://www.amgen.com/role/InvestmentsAvailableforsaleInvestmentsDetailsTextual",
     "shortName": "Investments (Available-for-sale Investments) (Details Textual)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:Cash",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R43": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:InvestmentsClassifiedByContractualMaturityDateTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2422410 - Disclosure - Investments (Fair Values by Contractual Maturity) (Details)",
     "role": "http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails",
     "shortName": "Investments (Fair Values by Contractual Maturity) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:InvestmentsClassifiedByContractualMaturityDateTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R44": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:EquitySecuritiesFvNi",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2423411 - Disclosure - Investments (Equity Securities) (Details Textual)",
     "role": "http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual",
     "shortName": "Investments (Equity Securities) (Details Textual)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R45": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:PaymentsToAcquireEquityMethodInvestments",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2424412 - Disclosure - Investments Investments (Limited Partnership Investments) (Details)",
     "role": "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails",
     "shortName": "Investments Investments (Limited Partnership Investments) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i84a786cd4d99438e85fec21c4c798f36_I20201231",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:AlternativeInvestment",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R46": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfInventoryCurrentTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:InventoryRawMaterialsNetOfReserves",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2427413 - Disclosure - Inventories (Details)",
     "role": "http://www.amgen.com/role/InventoriesDetails",
     "shortName": "Inventories (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfInventoryCurrentTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:InventoryRawMaterialsNetOfReserves",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R47": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i3fa2d8396a304f96bf7624f5d6125c76_I20201231",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:Goodwill",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2430414 - Disclosure - Goodwill and other intangible assets (Goodwill Roll Forward) (Details)",
     "role": "http://www.amgen.com/role/GoodwillandotherintangibleassetsGoodwillRollForwardDetails",
     "shortName": "Goodwill and other intangible assets (Goodwill Roll Forward) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfGoodwillTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:GoodwillForeignCurrencyTranslationGainLoss",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R48": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "amgn:ScheduleOfIntangibleAssetsTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:FiniteLivedIntangibleAssetsGross",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2431415 - Disclosure - Goodwill and other intangible assets (Identifiable Intangible Assets) (Details)",
     "role": "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails",
     "shortName": "Goodwill and other intangible assets (Identifiable Intangible Assets) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "amgn:ScheduleOfIntangibleAssetsTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:FiniteLivedIntangibleAssetsGross",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R49": {
     "firstAnchor": {
      "ancestors": [
       "ix:continuation",
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:AmortizationOfIntangibleAssets",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2432416 - Disclosure - Goodwill and other intangible assets (Details Textual)",
     "role": "http://www.amgen.com/role/GoodwillandotherintangibleassetsDetailsTextual",
     "shortName": "Goodwill and other intangible assets (Details Textual)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "ix:continuation",
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:AmortizationOfIntangibleAssets",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R5": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "INF",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:CommonStockParOrStatedValuePerShare",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usdPerShare",
      "xsiNil": "false"
     },
     "groupType": "statement",
     "isDefault": "false",
     "longName": "1004005 - Statement - Condensed Consolidated Balance Sheets (Parenthetical)",
     "role": "http://www.amgen.com/role/CondensedConsolidatedBalanceSheetsParenthetical",
     "shortName": "Condensed Consolidated Balance Sheets (Parenthetical)",
     "subGroupType": "parenthetical",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "INF",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:CommonStockParOrStatedValuePerShare",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usdPerShare",
      "xsiNil": "false"
     }
    },
    "R50": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfDebtInstrumentsTextBlock",
       "us-gaap:DebtDisclosureTextBlock",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2435417 - Disclosure - Financing arrangements (Principal Amounts and Carrying Value of Long-term Borrowings) (Details)",
     "role": "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails",
     "shortName": "Financing arrangements (Principal Amounts and Carrying Value of Long-term Borrowings) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfDebtInstrumentsTextBlock",
       "us-gaap:DebtDisclosureTextBlock",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R51": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i33a19bf9151948efb174bed3a79387f0_I20210930",
      "decimals": "-8",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DebtInstrumentFaceAmount",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2436418 - Disclosure - Financing arrangements (Details Textual)",
     "role": "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
     "shortName": "Financing arrangements (Details Textual)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "ia312c6387bbf40488704796f2339d92c_D20210101-20210930",
      "decimals": null,
      "lang": "en-US",
      "name": "amgn:DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R52": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "ia3569d0c6bcd4203a1148cb8dda584fe_I20210930",
      "decimals": "-8",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DerivativeNotionalAmount",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2437419 - Disclosure - Financing arrangements (interest rate swaps textual interim only) (Details)",
     "role": "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails",
     "shortName": "Financing arrangements (interest rate swaps textual interim only) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i434c36284fce4b0fb4ec413faf8330f4_I20210930",
      "decimals": "INF",
      "lang": "en-US",
      "name": "us-gaap:DerivativeBasisSpreadOnVariableRate",
      "reportCount": 1,
      "unique": true,
      "unitRef": "number",
      "xsiNil": "false"
     }
    },
    "R53": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "amgn:StockRepurchaseProgramTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "-5",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:StockRepurchasedDuringPeriodShares",
      "reportCount": 1,
      "unique": true,
      "unitRef": "shares",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2440420 - Disclosure - Stockholders' equity (Share Repurchase Program) (Details)",
     "role": "http://www.amgen.com/role/StockholdersequityShareRepurchaseProgramDetails",
     "shortName": "Stockholders' equity (Share Repurchase Program) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "amgn:StockRepurchaseProgramTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "-5",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:StockRepurchasedDuringPeriodShares",
      "reportCount": 1,
      "unique": true,
      "unitRef": "shares",
      "xsiNil": "false"
     }
    },
    "R54": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "ibb4ad07750104a41ad551ce7e97f7afe_I20210630",
      "decimals": "INF",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:StockRepurchaseProgramAuthorizedAmount1",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2441421 - Disclosure - Stockholders' equity (Details Textual) (Details)",
     "role": "http://www.amgen.com/role/StockholdersequityDetailsTextualDetails",
     "shortName": "Stockholders' equity (Details Textual) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "ibb4ad07750104a41ad551ce7e97f7afe_I20210630",
      "decimals": "INF",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:StockRepurchaseProgramAuthorizedAmount1",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R55": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "ibb4ad07750104a41ad551ce7e97f7afe_I20210630",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:StockholdersEquity",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2442422 - Disclosure - Stockholders' equity (Components of AOCI) (Details)",
     "role": "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails",
     "shortName": "Stockholders' equity (Components of AOCI) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "ief03f026e49a44918a54a590451e6db3_D20210701-20210930",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R56": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2443423 - Disclosure - Stockholders' equity (Reclassifications out of AOCI) (Details)",
     "role": "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails",
     "shortName": "Stockholders' equity (Reclassifications out of AOCI) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i774914ff61704f25a808fe591907f07a_D20210701-20210930",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R57": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:InvestmentsClassifiedByContractualMaturityDateTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:AvailableForSaleSecuritiesDebtSecurities",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2446424 - Disclosure - Fair value measurement (Details)",
     "role": "http://www.amgen.com/role/FairvaluemeasurementDetails",
     "shortName": "Fair value measurement (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:AssetsFairValueDisclosure",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R58": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:MaximumLengthOfTimeForeignCurrencyCashFlowHedge",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2447425 - Disclosure - Fair value measurement (Details Textual)",
     "role": "http://www.amgen.com/role/FairvaluemeasurementDetailsTextual",
     "shortName": "Fair value measurement (Details Textual)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:MaximumLengthOfTimeForeignCurrencyCashFlowHedge",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    },
    "R59": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "ia3569d0c6bcd4203a1148cb8dda584fe_I20210930",
      "decimals": "-8",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DerivativeNotionalAmount",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2453427 - Disclosure - Derivative instruments (Details Textual)",
     "role": "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
     "shortName": "Derivative instruments (Details Textual)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i0d2698f3fe114fea898dbd1bedfa2f5c_I20210930",
      "decimals": "-8",
      "lang": "en-US",
      "name": "us-gaap:DerivativeNotionalAmount",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R6": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i9383ea8be6554a1fab020c889f98f560_I20191231",
      "decimals": "-5",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:CommonStockSharesOutstanding",
      "reportCount": 1,
      "unitRef": "shares",
      "xsiNil": "false"
     },
     "groupType": "statement",
     "isDefault": "false",
     "longName": "1005006 - Statement - Condensed Consolidated Statements of Stockholders' Equity",
     "role": "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity",
     "shortName": "Condensed Consolidated Statements of Stockholders' Equity",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "ic041513a75144cdd9d651b4d92760425_D20200101-20200331",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:NetIncomeLoss",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R60": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "amgn:ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i7734e6b3c1704f4d8a988d1a61348a77_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DerivativeNotionalAmount",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2454428 - Disclosure - Derivative instruments (Cross-currency Swaps) (Details)",
     "role": "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
     "shortName": "Derivative instruments (Cross-currency Swaps) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "amgn:ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i7734e6b3c1704f4d8a988d1a61348a77_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DerivativeNotionalAmount",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R61": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i53af41683cb14e598e98d0cdd138caeb_D20210701-20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2455429 - Disclosure - Derivative instruments (Effective Portion of Unrealized Gain (Loss)) (Details)",
     "role": "http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails",
     "shortName": "Derivative instruments (Effective Portion of Unrealized Gain (Loss)) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i53af41683cb14e598e98d0cdd138caeb_D20210701-20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R62": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfDebtInstrumentsTextBlock",
       "us-gaap:DebtDisclosureTextBlock",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "if5d69d61a77e45e8a5690b1247306be3_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2456430 - Disclosure - Derivative instruments (Hedged Liabilities and Cumulative Amount) (Details)",
     "role": "http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails",
     "shortName": "Derivative instruments (Hedged Liabilities and Cumulative Amount) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i44869b7e4ad641a5bc2667496e4c4b2c_I20210930",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:HedgedLiabilityFairValueHedge",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R63": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i5c9f553a648c448983067995570fff40_D20210701-20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2457431 - Disclosure - Derivative instruments (Summary of Income and Expense Line Items) (Details)",
     "role": "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
     "shortName": "Derivative instruments (Summary of Income and Expense Line Items) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "icc69b7bd76f6439ea5993cfe7cab843b_D20210701-20210930",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R64": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "ic5f888563c394d598153a924bfacbca4_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DerivativeFairValueOfDerivativeAsset",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2458432 - Disclosure - Derivative instruments (Fair Value of Derivatives) (Details)",
     "role": "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails",
     "shortName": "Derivative instruments (Fair Value of Derivatives) (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "us-gaap:ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "ic5f888563c394d598153a924bfacbca4_I20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:DerivativeFairValueOfDerivativeAsset",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R65": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2cc9eff2f67a40c98702116571cdb627_D20210928-20210928",
      "decimals": "INF",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:GainContingencyPatentsFoundInfringedUponNumber",
      "reportCount": 1,
      "unique": true,
      "unitRef": "patent",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2460433 - Disclosure - Contingencies and commitments (Details)",
     "role": "http://www.amgen.com/role/ContingenciesandcommitmentsDetails",
     "shortName": "Contingencies and commitments (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2cc9eff2f67a40c98702116571cdb627_D20210928-20210928",
      "decimals": "INF",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:GainContingencyPatentsFoundInfringedUponNumber",
      "reportCount": 1,
      "unique": true,
      "unitRef": "patent",
      "xsiNil": "false"
     }
    },
    "R66": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i7b7289e4de274a45a8d257b031b3ad23_D20211019-20211019",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:PaymentsToAcquireBusinessesGross",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2462434 - Disclosure - Subsequent events (Details)",
     "role": "http://www.amgen.com/role/SubsequenteventsDetails",
     "shortName": "Subsequent events (Details)",
     "subGroupType": "details",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i7b7289e4de274a45a8d257b031b3ad23_D20211019-20211019",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:PaymentsToAcquireBusinessesGross",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R7": {
     "firstAnchor": {
      "ancestors": [
       "us-gaap:CommonStockDividendsPerShareCashPaid",
       "us-gaap:CommonStockDividendsPerShareCashPaid",
       "us-gaap:CommonStockDividendsPerShareCashPaid",
       "us-gaap:CommonStockDividendsPerShareDeclared",
       "span",
       "div",
       "ix:continuation",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i57518655effb4de5bdcffb7396c85dc7_D20210701-20210731",
      "decimals": "2",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:CommonStockDividendsPerShareDeclared",
      "reportCount": 1,
      "unitRef": "usdPerShare",
      "xsiNil": "false"
     },
     "groupType": "statement",
     "isDefault": "false",
     "longName": "1006007 - Statement - Condensed Consolidated Statements of Stockholders' Equity (Parenthetical)",
     "role": "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquityParenthetical",
     "shortName": "Condensed Consolidated Statements of Stockholders' Equity (Parenthetical)",
     "subGroupType": "parenthetical",
     "uniqueAnchor": null
    },
    "R8": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": "-6",
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:NetIncomeLoss",
      "reportCount": 1,
      "unitRef": "usd",
      "xsiNil": "false"
     },
     "groupType": "statement",
     "isDefault": "false",
     "longName": "1007008 - Statement - Condensed Consolidated Statements of Cash Flows",
     "role": "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows",
     "shortName": "Condensed Consolidated Statements of Cash Flows",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "td",
       "tr",
       "table",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": "-6",
      "lang": "en-US",
      "name": "us-gaap:DepreciationDepletionAndAmortization",
      "reportCount": 1,
      "unique": true,
      "unitRef": "usd",
      "xsiNil": "false"
     }
    },
    "R9": {
     "firstAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:SignificantAccountingPoliciesTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "disclosure",
     "isDefault": "false",
     "longName": "2101101 - Disclosure - Summary of significant accounting policies",
     "role": "http://www.amgen.com/role/Summaryofsignificantaccountingpolicies",
     "shortName": "Summary of significant accounting policies",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "span",
       "div",
       "body",
       "html"
      ],
      "baseRef": "amgn-20210930.htm",
      "contextRef": "i2dd3903567ca42279a1488ed136b31bf_D20210101-20210930",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "us-gaap:SignificantAccountingPoliciesTextBlock",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    }
   },
   "segmentCount": 109,
   "tag": {
    "amgn_A1.250SeniorNotesDue2022Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "1.250% Senior Notes Due 2022 [Member]",
        "label": "1.250% Senior Notes Due 2022 [Member]",
        "terseLabel": "1.250% Senior Notes Due 2022 [Member]"
       }
      }
     },
     "localname": "A1.250SeniorNotesDue2022Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_A2.00SeniorNotesDue2026Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "2.00% Senior Notes Due 2026 [Member]",
        "label": "2.00% Senior Notes Due 2026 [Member]",
        "terseLabel": "2.00% Senior Notes Due 2026 [Member]"
       }
      }
     },
     "localname": "A2.00SeniorNotesDue2026Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_A2030And2021NoteHedgesMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "2030 And 2021 Note Hedges",
        "label": "2030 And 2021 Note Hedges [Member]",
        "terseLabel": "2030 And 2021 Note Hedges"
       }
      }
     },
     "localname": "A2030And2021NoteHedgesMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_A300NotesDue20523002052NotesMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "3.00% notes due 2052 (3.00% 2052 Notes)",
        "label": "3.00% notes due 2052 (3.00% 2052 Notes) [Member]",
        "terseLabel": "3.00% notes due 2052 (3.00% 2052 Notes)"
       }
      }
     },
     "localname": "A300NotesDue20523002052NotesMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_AccruedLiabilitiesOtherNonCurrentLiabilitiesMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Accrued liabilities/other non-current liabilities.",
        "label": "Accrued Liabilities Other Non Current Liabilities [Member]",
        "verboseLabel": "Accrued liabilities/Other noncurrent liabilities [Member]"
       }
      }
     },
     "localname": "AccruedLiabilitiesOtherNonCurrentLiabilitiesMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_AccumulatedOtherAdjustmentAttributabletoParentMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Accumulated Other Adjustment Attributable to Parent [Member]",
        "label": "Accumulated Other Adjustment Attributable to Parent [Member]",
        "terseLabel": "Other [Member]"
       }
      }
     },
     "localname": "AccumulatedOtherAdjustmentAttributabletoParentMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_AcquiredResearchAndDevelopmentTechnologyRightsMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Acquired research and development technology rights.",
        "label": "Acquired Research And Development Technology Rights [Member]",
        "terseLabel": "Research and Development Technology Rights [Member]"
       }
      }
     },
     "localname": "AcquiredResearchAndDevelopmentTechnologyRightsMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_AlternativeInvestmentNetGainLoss": {
     "auth_ref": [],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Alternative Investment, Net Gain (Loss)",
        "label": "Alternative Investment, Net Gain (Loss)",
        "terseLabel": "Net gains (losses) from limited partnership investments"
       }
      }
     },
     "localname": "AlternativeInvestmentNetGainLoss",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/IncometaxesDetails",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_AranespMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Aranesp.",
        "label": "Aranesp [Member]",
        "terseLabel": "Aranesp\u00ae (darbepoetin alfa) [Member]"
       }
      }
     },
     "localname": "AranespMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue": {
     "auth_ref": [],
     "calculation": {
      "http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails": {
       "order": 2.0,
       "parentTag": "us-gaap_AvailableForSaleSecuritiesDebtSecurities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Available-For Sale Securities, Debt Maturities, After One Through Three Years, Fair Value",
        "label": "Available-For Sale Securities, Debt Maturities, After One Through Three Years, Fair Value",
        "terseLabel": "Maturing after one year through three years"
       }
      }
     },
     "localname": "AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughThreeYearsFairValue",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue": {
     "auth_ref": [],
     "calculation": {
      "http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails": {
       "order": 3.0,
       "parentTag": "us-gaap_AvailableForSaleSecuritiesDebtSecurities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Available-For-Sale Securities, Debt Maturities, After Three Through Five Years, Fair Value",
        "label": "Available-For-Sale Securities, Debt Maturities, After Three Through Five Years, Fair Value",
        "terseLabel": "Maturing after three years through five years"
       }
      }
     },
     "localname": "AvailableForSaleSecuritiesDebtMaturitiesAfterThreeThroughFiveYearsFairValue",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_AvailableForSalesInvestmentsMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Available for sales investments.",
        "label": "Available For Sales Investments [Member]",
        "verboseLabel": "Available-for-sale investments [Member]"
       }
      }
     },
     "localname": "AvailableForSalesInvestmentsMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_BasicAndDilutedEarningPerShareAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Basic and diluted earning per share.",
        "label": "Basic And Diluted Earning Per Share [Abstract]",
        "verboseLabel": "Computation of basic and diluted earnings per share"
       }
      }
     },
     "localname": "BasicAndDilutedEarningPerShareAbstract",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/EarningspershareDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "amgn_BasisOfPresentationPolicyTextBlock": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Shows the basis of presentation of financial information for interim periods.",
        "label": "Basis Of Presentation [Policy Text Block]",
        "verboseLabel": "Basis of presentation"
       }
      }
     },
     "localname": "BasisOfPresentationPolicyTextBlock",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesPolicies"
     ],
     "xbrltype": "textBlockItemType"
    },
    "amgn_BeiGeneMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "BeiGene [Member]",
        "label": "BeiGene [Member]",
        "terseLabel": "Collaborative arrangement with BeiGene, Ltd. [Member]",
        "verboseLabel": "BeiGene [Member]"
       }
      }
     },
     "localname": "BeiGeneMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions": {
     "auth_ref": [],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Business Combination, Fair Value of Contingent Consideration Arrangements, Addition from Acquisitions",
        "label": "Business Combination, Fair Value of Contingent Consideration Arrangements, Addition from Acquisitions",
        "terseLabel": "Addition from Kirin-Amgen acquisition"
       }
      }
     },
     "localname": "BusinessCombinationFairValueofContingentConsiderationArrangementsAdditionfromAcquisitions",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_CorporateDebtSecuritiesFinancialMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Corporate debt securities financial Member.",
        "label": "Corporate Debt Securities Financial [Member]",
        "terseLabel": "Corporate debt securities - Financial [Member]"
       }
      }
     },
     "localname": "CorporateDebtSecuritiesFinancialMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_CorporateDebtSecuritiesIndustrialMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Corporate debt securities industrial Member.",
        "label": "Corporate Debt Securities Industrial [Member]",
        "terseLabel": "Corporate debt securities - Industrial [Member]"
       }
      }
     },
     "localname": "CorporateDebtSecuritiesIndustrialMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_CorporateDebtSecuritiesOtherMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Corporate debt securities other.",
        "label": "Corporate Debt Securities Other [Member]",
        "terseLabel": "Corporate debt securities - Other [Member]"
       }
      }
     },
     "localname": "CorporateDebtSecuritiesOtherMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_CrossCurrencySwapContractsMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Cross currency swap contracts.",
        "label": "Cross Currency Swap Contracts [Member]",
        "netLabel": "Cross-currency swap contract [Member]",
        "terseLabel": "Cross-currency swap contracts [Member]",
        "verboseLabel": "Cross-currency swap contracts [Member]"
       }
      }
     },
     "localname": "CrossCurrencySwapContractsMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_DebtExchangeAdditionalCashConsideration": {
     "auth_ref": [],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Debt exchange additional cash consideration paid",
        "label": "Debt exchange additional cash consideration",
        "terseLabel": "debt exchange additional cash consideration"
       }
      }
     },
     "localname": "DebtExchangeAdditionalCashConsideration",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Debt Instrument, Redemption Period without Payment of Make Whole Amount",
        "label": "Debt Instrument, Redemption Period without Payment of Make Whole Amount",
        "terseLabel": "Debt Instrument, Redemption Period without Payment of Make Whole Amount"
       }
      }
     },
     "localname": "DebtInstrumentRedemptionPeriodWithoutPaymentOfMakeWholeAmount",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual"
     ],
     "xbrltype": "durationItemType"
    },
    "amgn_DerivativeAssetsFairValueDisclosureAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Derivative assets.",
        "label": "Derivative Assets Fair Value Disclosure [Abstract]",
        "verboseLabel": "Derivatives:"
       }
      }
     },
     "localname": "DerivativeAssetsFairValueDisclosureAbstract",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Derivative financial instruments liabilities fair value disclosure.",
        "label": "Derivative Financial Instruments Liabilities Fair Value Disclosure [Abstract]",
        "verboseLabel": "Derivatives:"
       }
      }
     },
     "localname": "DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "amgn_DerivativeInstrumentNameAxis": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Derivative Instrument, Name",
        "label": "Derivative Instrument, Name [Axis]",
        "terseLabel": "Derivative Instrument, Name [Axis]"
       }
      }
     },
     "localname": "DerivativeInstrumentNameAxis",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual"
     ],
     "xbrltype": "stringItemType"
    },
    "amgn_DerivativeInstrumentNameDomain": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Derivative Instrument, Name [Domain]",
        "label": "Derivative Instrument, Name [Domain]",
        "terseLabel": "Derivative Instrument, Name [Domain]"
       }
      }
     },
     "localname": "DerivativeInstrumentNameDomain",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_EnbrelMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "ENBREL.",
        "label": "ENBREL [Member]",
        "terseLabel": "Enbrel\u00ae (etanercept) [Member]"
       }
      }
     },
     "localname": "EnbrelMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity": {
     "auth_ref": [],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Equity Method Investment, Amortization of Difference Between Carrying Amount and Underlying Equity",
        "label": "Equity Method Investment, Amortization of Difference Between Carrying Amount and Underlying Equity",
        "terseLabel": "Equity Method Investment, Amortization of Difference Between Carrying Amount and Underlying Equity"
       }
      }
     },
     "localname": "EquityMethodInvestmentAmortizationOfDifferenceBetweenCarryingAmountAndUnderlyingEquity",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_EquityMethodInvestmentChangeInCarryingValue": {
     "auth_ref": [],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Equity method investment, change in carrying value",
        "label": "Equity method investment, change in carrying value",
        "terseLabel": "Equity method investment, change in carrying value"
       }
      }
     },
     "localname": "EquityMethodInvestmentChangeInCarryingValue",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_EquityMethodInvestmentChangeInCarryingValueOther": {
     "auth_ref": [],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Equity Method Investment, Change In Carrying Value, Other",
        "label": "Equity Method Investment, Change In Carrying Value, Other",
        "terseLabel": "Equity Method Investment, Change In Carrying Value, Other"
       }
      }
     },
     "localname": "EquityMethodInvestmentChangeInCarryingValueOther",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair values of available-for-sale investments by classification in the Consolidated Balance Sheets.",
        "label": "Fair Values Of Available For Sale Investments By Classification In Consolidated Balance Sheets [Abstract]",
        "verboseLabel": "Fair values of available-for-sale investments by classification in the Consolidated Balance Sheets"
       }
      }
     },
     "localname": "FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsAbstract",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "amgn_FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of fair values of available-for-sale investments by classification in the consolidated balance sheets.",
        "label": "Fair Values of Available for Sale Investments By Classification In Consolidated Balance Sheets [Table Text Block]",
        "verboseLabel": "Fair values of available-for-sale investments by classification in the Consolidated Balance Sheets"
       }
      }
     },
     "localname": "FairValuesOfAvailableForSaleInvestmentsByClassificationInConsolidatedBalanceSheetsTableTextBlock",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "amgn_FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair Values Of Both Derivatives Designated As Hedging Instruments And Not Designated As Hedging Instruments Included In Condensed Consolidated Balance Sheets.",
        "label": "Fair Values Of Both Derivatives Designated As Hedging Instruments And Not Designated As Hedging Instruments Included In Condensed Consolidated Balance Sheets [Abstract]",
        "verboseLabel": "Fair values of both derivatives designated as hedging instruments and not designated as hedging instruments included in Condensed Consolidated Balance Sheets"
       }
      }
     },
     "localname": "FairValuesOfBothDerivativesDesignatedAsHedgingInstrumentsAndNotDesignatedAsHedgingInstrumentsIncludedInCondensedConsolidatedBalanceSheetsAbstract",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Five Point Five Zero Percent Pound Sterling Notes Due 2026 [Member]",
        "label": "Five Point Five Zero Percent Pound Sterling Notes Due 2026 [Member]",
        "terseLabel": "5.50% \u00a3475 million notes due 2026 (5.50% 2026 pound sterling Notes) [Member]",
        "verboseLabel": "5.50% 2026 pound sterling Notes [Member]"
       }
      }
     },
     "localname": "FivePointFiveZeroPercentPoundSterlingNotesDue2026Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_FivePointOneFivePercentNotesDue2041Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Five Point One Five Percent Notes Due 2041 [Member]",
        "label": "Five Point One Five Percent Notes Due 2041 [Member]",
        "terseLabel": "5.15% notes due 2041 (5.15% 2041 Notes) [Member]"
       }
      }
     },
     "localname": "FivePointOneFivePercentNotesDue2041Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_FivePointSevenFivePercentNotesDue2040Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Five Point Seven Five Percent Notes Due 2040 [Member]",
        "label": "Five Point Seven Five Percent Notes Due 2040 [Member]",
        "terseLabel": "5.75% notes due 2040 (5.75% 2040 Notes) [Member]"
       }
      }
     },
     "localname": "FivePointSevenFivePercentNotesDue2040Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_FivePointSixFivePercentNotesDue2042Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Five Point Six Five Percent Notes Due 2042 [Member]",
        "label": "Five Point Six Five Percent Notes Due 2042 [Member]",
        "terseLabel": "5.65% notes due 2042 (5.65% 2042 Notes) [Member]"
       }
      }
     },
     "localname": "FivePointSixFivePercentNotesDue2042Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_FivePointThreeSevenFivePercentNotesDue2043Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Five Point Three Seven Five Percent Notes Due 2043 [Member]",
        "label": "Five Point Three Seven Five Percent Notes Due 2043 [Member]",
        "terseLabel": "5.375% notes due 2043 (5.375% 2043 Notes) [Member]"
       }
      }
     },
     "localname": "FivePointThreeSevenFivePercentNotesDue2043Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_FivePrimeTherapeuticsIncMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Five Prime Therapeutics, Inc.",
        "label": "Five Prime Therapeutics, Inc. [Member]",
        "terseLabel": "Five Prime Therapeutics, Inc."
       }
      }
     },
     "localname": "FivePrimeTherapeuticsIncMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_FloatingRateNotesDue2020Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Floating Rate Notes Due 2020 [Member]",
        "label": "Floating Rate Notes Due 2020 [Member]",
        "terseLabel": "Floating Rate Notes Due 2020 [Member]"
       }
      }
     },
     "localname": "FloatingRateNotesDue2020Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_ForeignCurrencyAndCrossCurrencySwapsMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Foreign currency and cross currency swaps.",
        "label": "Foreign Currency and Cross Currency Swaps [Member]",
        "terseLabel": "Foreign currency and cross currency swap contracts [Member]"
       }
      }
     },
     "localname": "ForeignCurrencyAndCrossCurrencySwapsMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_FourPercentPoundSterlingNotesDue2029Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Four Percent Pound Sterling Notes Due 2029 [Member]",
        "label": "Four Percent Pound Sterling Notes Due 2029 [Member]",
        "terseLabel": "4.00% \u00a3700 million notes due 2029 (4.00% 2029 pound sterling Notes) [Member]",
        "verboseLabel": "4.00% 2029 pound sterling Notes [Member]"
       }
      }
     },
     "localname": "FourPercentPoundSterlingNotesDue2029Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Four Point Five Six Three Percent Notes Due Two Zero Four Eight [Member]",
        "label": "Four Point Five Six Three Percent Notes Due Two Zero Four Eight [Member]",
        "terseLabel": "4.563% notes due 2048 (4.563% 2048 Notes) [Member]",
        "verboseLabel": "4.563% notes due 2048 (4.563% 2048 Notes) [Member]"
       }
      }
     },
     "localname": "FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_FourPointFiveZeroPercentNotesDue2020Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Four Point Five Zero Percent Notes Due 2020 [Member]",
        "label": "Four Point Five Zero Percent Notes Due 2020 [Member]",
        "terseLabel": "4.50% notes due 2020 (4.50% 2020 Notes) [Member]"
       }
      }
     },
     "localname": "FourPointFiveZeroPercentNotesDue2020Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Four Point Four Zero Percent Notes Due Two Zero Four Five [Member]",
        "label": "Four Point Four Zero Percent Notes Due Two Zero Four Five [Member]",
        "terseLabel": "4.40% notes due 2045 (4.40% 2045 Notes) [Member]"
       }
      }
     },
     "localname": "FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_FourPointNineFivePercentNotesDue2041Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Four Point Nine Five Percent Notes Due 2041 [Member]",
        "label": "Four Point Nine Five Percent Notes Due 2041 [Member]",
        "terseLabel": "4.95% notes due 2041 (4.95% 2041 Notes) [Member]"
       }
      }
     },
     "localname": "FourPointNineFivePercentNotesDue2041Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_FourPointOneZeroPercentNotesDue2021Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Four Point One Zero Percent Notes Due 2021 [Member]",
        "label": "Four Point One Zero Percent Notes Due 2021 [Member]",
        "terseLabel": "4.10% notes due 2021 (4.10% 2021 Notes) [Member]"
       }
      }
     },
     "localname": "FourPointOneZeroPercentNotesDue2021Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Four Point Six Six Three Percent Notes Due Two Zero Five One [Member]",
        "label": "Four Point Six Six Three Percent Notes Due Two Zero Five One [Member]",
        "terseLabel": "4.663% notes due 2051 (4.663% 2051 Notes) [Member]"
       }
      }
     },
     "localname": "FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_HedgedLiabilityDiscontinuedFairValueHedge": {
     "auth_ref": [],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Hedged Liability, Discontinued Fair Value Hedge",
        "label": "Hedged Liability, Discontinued Fair Value Hedge",
        "terseLabel": "Carrying value with discontinued hedging relationships"
       }
      }
     },
     "localname": "HedgedLiabilityDiscontinuedFairValueHedge",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_HospiraMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Hospira [Member]",
        "label": "Hospira [Member]",
        "terseLabel": "Hospira, Inc. [Member]"
       }
      }
     },
     "localname": "HospiraMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_HumiraBiosimilarAntitrustClassActionsMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Humira Biosimilar Antitrust Class Actions [Member]",
        "label": "Humira Biosimilar Antitrust Class Actions [Member]",
        "terseLabel": "Humira Biosimilar Antitrust Class Actions [Member]"
       }
      }
     },
     "localname": "HumiraBiosimilarAntitrustClassActionsMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_IdentifiableIntangibleAssetsAccumulatedAmortization": {
     "auth_ref": [],
     "calculation": {
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails": {
       "order": 2.0,
       "parentTag": "us-gaap_IntangibleAssetsNetExcludingGoodwill",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Identifiable intangible assets accumulated amortization.",
        "label": "Identifiable Intangible Assets Accumulated Amortization",
        "negatedLabel": "Accumulated amortization"
       }
      }
     },
     "localname": "IdentifiableIntangibleAssetsAccumulatedAmortization",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_IdentifiableIntangibleAssetsGross": {
     "auth_ref": [],
     "calculation": {
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails": {
       "order": 1.0,
       "parentTag": "us-gaap_IntangibleAssetsNetExcludingGoodwill",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Identifiable intangible assets gross.",
        "label": "Identifiable Intangible Assets Gross",
        "terseLabel": "Gross carrying amount"
       }
      }
     },
     "localname": "IdentifiableIntangibleAssetsGross",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_IncreaseDecreaseInNoncurrentTaxLiability": {
     "auth_ref": [],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 11.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Increase (Decrease) In Noncurrent Tax Liability",
        "label": "Increase (Decrease) In Noncurrent Tax Liability",
        "terseLabel": "Long-term tax liabilities"
       }
      }
     },
     "localname": "IncreaseDecreaseInNoncurrentTaxLiability",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_KANJINTIPatentLitigationMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "KANJINTI Patent Litigation [Member]",
        "label": "KANJINTI Patent Litigation [Member]",
        "terseLabel": "KANJINTI Patent Litigation [Member]"
       }
      }
     },
     "localname": "KANJINTIPatentLitigationMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_KyowaKirinCoLtdMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Kyowa Kirin Co. Ltd.",
        "label": "Kyowa Kirin Co. Ltd. [Member]",
        "terseLabel": "Kyowa Kirin Co. Ltd."
       }
      }
     },
     "localname": "KyowaKirinCoLtdMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_KyprolisANDAPatentLitigationMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Kyprolis ANDA Patent Litigation",
        "label": "Kyprolis ANDA Patent Litigation [Member]",
        "terseLabel": "Kyprolis ANDA Patent Litigation"
       }
      }
     },
     "localname": "KyprolisANDAPatentLitigationMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_KyprolisMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Kyprolis [Member]",
        "label": "Kyprolis [Member]",
        "terseLabel": "KYPROLIS\u00ae (carfilzomib) [Member]"
       }
      }
     },
     "localname": "KyprolisMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails",
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_LitigationSettlementDamagesSoughtValue": {
     "auth_ref": [],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Litigation Settlement, Damages Sought, Value",
        "label": "Litigation Settlement, Damages Sought, Value",
        "terseLabel": "Amount awarded from settlement"
       }
      }
     },
     "localname": "LitigationSettlementDamagesSoughtValue",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_LongTermDebtCurrentMaturitiesMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Long-Term Debt, Current Maturities [Member]",
        "label": "Long-Term Debt, Current Maturities [Member]",
        "terseLabel": "Current portion of long-term debt [Member]"
       }
      }
     },
     "localname": "LongTermDebtCurrentMaturitiesMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_LossContingencyAppealPeriod": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Loss Contingency, appeal period",
        "label": "Loss Contingency, appeal period",
        "terseLabel": "Loss Contingency, appeal period"
       }
      }
     },
     "localname": "LossContingencyAppealPeriod",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "durationItemType"
    },
    "amgn_LossContingencyNumberOfLawsuits": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Loss Contingency, Number Of Lawsuits",
        "label": "Loss Contingency, Number Of Lawsuits",
        "terseLabel": "Number of lawsuits"
       }
      }
     },
     "localname": "LossContingencyNumberOfLawsuits",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "integerItemType"
    },
    "amgn_LossContingencyPatentsExpiredNumber": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Loss Contingency, Patents Expired, Number",
        "label": "Loss Contingency, Patents Expired, Number",
        "terseLabel": "Number of asserted patents expired"
       }
      }
     },
     "localname": "LossContingencyPatentsExpiredNumber",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "integerItemType"
    },
    "amgn_NatureOfOperationsPolicyTextBlock": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Describes the nature of an entity's business, the major products or services it sells or provides and its principal markets, including the locations of those markets. If the entity operates in more than one business, the disclosure also indicates the relative importance of its operations in each business and the basis for the determination (for example, assets, revenues, or earnings). Disclosures about the nature of operations need not be quantified; relative importance could be conveyed by use of terms such as \"predominately\", \"about equally\", or \"major and other\". This element is also referred to as \"Business Description\".",
        "label": "Nature Of Operations [Policy Text Block]",
        "verboseLabel": "Business"
       }
      }
     },
     "localname": "NatureOfOperationsPolicyTextBlock",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesPolicies"
     ],
     "xbrltype": "textBlockItemType"
    },
    "amgn_NeulastaMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Neulasta.",
        "label": "Neulasta [Member]",
        "terseLabel": "Neulasta\u00ae (pegfilgrastim) [Member]"
       }
      }
     },
     "localname": "NeulastaMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_NeumoraTherapeuticsIncMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Neumora Therapeutics, Inc.",
        "label": "Neumora Therapeutics, Inc. [Member]",
        "terseLabel": "Neumora Therapeutics, Inc. [Member]"
       }
      }
     },
     "localname": "NeumoraTherapeuticsIncMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_NovartisPharmaAGMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Novartis Pharma AG",
        "label": "Novartis Pharma AG [Member]",
        "terseLabel": "Novartis Pharma AG"
       }
      }
     },
     "localname": "NovartisPharmaAGMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_NumberOfAssertedPatents": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Number Of Asserted Patents",
        "label": "Number Of Asserted Patents",
        "terseLabel": "Number Of Asserted Patents"
       }
      }
     },
     "localname": "NumberOfAssertedPatents",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "integerItemType"
    },
    "amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "One Point Eight Five Percent Notes Due Two Zero Two One [Member]",
        "label": "One Point Eight Five Percent Notes Due Two Zero Two One [Member]",
        "terseLabel": "1.85% notes due 2021 (1.85% 2021 Notes) [Member]"
       }
      }
     },
     "localname": "OnePointEightFivePercentNotesDueTwoZeroTwoOneMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "One Point Nine Zero Percent Notes Due Two Zero Two Five [Member]",
        "label": "One Point Nine Zero Percent Notes Due Two Zero Two Five [Member]",
        "terseLabel": "1.90% notes due 2025 (1.90% 2025 Notes) [Member]"
       }
      }
     },
     "localname": "OnePointNineZeroPercentNotesDueTwoZeroTwoFiveMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_OnePointSixFivePercent2028NotesMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "One point six five percent 2028 Notes",
        "label": "One point six five percent 2028 Notes [Member]",
        "terseLabel": "1.65% notes due 2028 (1.65% 2028 Notes) [Member}"
       }
      }
     },
     "localname": "OnePointSixFivePercent2028NotesMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "One Point Twenty Five Percent Euro Notes Due Two Thousand Twenty Two [Member]",
        "label": "One Point Twenty Five Percent Euro Notes Due Two Thousand Twenty Two [Member]",
        "verboseLabel": "1.25% 2022 euro Notes [Member]"
       }
      }
     },
     "localname": "OnePointTwentyFivePercentEuroNotesDueTwoThousandTwentyTwoMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "One Point Two Five Percent Euro Notes due Two Zero Two Two [Member]",
        "label": "One Point Two Five Percent Euro Notes due Two Zero Two Two [Member]",
        "terseLabel": "1.25% \u20ac1,250 million notes due 2022 (1.25% 2022 euro Notes) [Member]"
       }
      }
     },
     "localname": "OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_OtezlaANDAPatentLitigationMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Otezla ANDA Patent Litigation",
        "label": "Otezla ANDA Patent Litigation [Member]",
        "terseLabel": "Otezla ANDA Patent Litigation [Member]"
       }
      }
     },
     "localname": "OtezlaANDAPatentLitigationMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_OtezlaMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Otezla [Member]",
        "label": "Otezla [Member]",
        "terseLabel": "Otezla (apremilast) [Member]"
       }
      }
     },
     "localname": "OtezlaMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax": {
     "auth_ref": [],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Other Comprehensive Income (Loss), Other Adjustment, before Tax",
        "label": "Other Comprehensive Income (Loss), Other Adjustment, before Tax",
        "terseLabel": "Other"
       }
      }
     },
     "localname": "OtherComprehensiveIncomeLossOtherAdjustmentbeforeTax",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent": {
     "auth_ref": [],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome": {
       "order": 4.0,
       "parentTag": "us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Other Comprehensive Income (Loss), Other Gains (Losses), Net of Tax, Portion Attributable to Parent",
        "label": "Other Comprehensive Income (Loss), Other Gains (Losses), Net of Tax, Portion Attributable to Parent",
        "terseLabel": "Other"
       }
      }
     },
     "localname": "OtherComprehensiveIncomeLossOtherGainsLossesNetOfTaxPortionAttributableToParent",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_OtherCurrentNoncurrentAssetsMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Other current assets/other non-current assets.",
        "label": "Other Current Noncurrent Assets [Member]",
        "verboseLabel": "Other current assets/Other assets [Member]"
       }
      }
     },
     "localname": "OtherCurrentNoncurrentAssetsMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_OtherNotesDue2097Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Other Notes Due 2097 [Member]",
        "label": "Other Notes Due 2097 [Member]",
        "terseLabel": "Other notes due 2097 [Member]"
       }
      }
     },
     "localname": "OtherNotesDue2097Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_OtherProductsMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Other Products [Member]",
        "label": "Other Products [Member]",
        "terseLabel": "Other products [Member]"
       }
      }
     },
     "localname": "OtherProductsMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_OtherShortTermInterestBearingSecuritiesMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Other short-term interest bearing securities.",
        "label": "Other Short Term Interest Bearing Securities [Member]",
        "verboseLabel": "Other short-term interest-bearing securities [Member]"
       }
      }
     },
     "localname": "OtherShortTermInterestBearingSecuritiesMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_PatentTrialAndAppealBoardPatentChallengesMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Patent Trial And Appeal Board Patent Challenges [Member]",
        "label": "Patent Trial And Appeal Board Patent Challenges [Member]",
        "terseLabel": "Patent Trial and Appeal Board Patent Challenges [Member]"
       }
      }
     },
     "localname": "PatentTrialAndAppealBoardPatentChallengesMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event",
        "label": "Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event",
        "terseLabel": "Percentage of Principal Amount of Notes that may be Paid Upon Occurrence of Change in Control Triggering Event"
       }
      }
     },
     "localname": "PercentageofPrincipalAmountofNotesthatmaybePaidUponOccurrenceofChangeinControlTriggeringEvent",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "percentItemType"
    },
    "amgn_ProliaMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Prolia.",
        "label": "Prolia [Member]",
        "terseLabel": "Prolia\u00ae (denosumab) [Member]"
       }
      }
     },
     "localname": "ProliaMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_ProposedAdditionalIncomeTax": {
     "auth_ref": [],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Proposed additional income tax",
        "label": "Proposed additional income tax",
        "terseLabel": "Proposed additional income tax"
       }
      }
     },
     "localname": "ProposedAdditionalIncomeTax",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/IncometaxesDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_RecoveryOfDirectCostsReceivable": {
     "auth_ref": [],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Recovery Of Direct Costs, Receivable",
        "label": "Recovery Of Direct Costs, Receivable",
        "terseLabel": "Receivable for direct costs owed"
       }
      }
     },
     "localname": "RecoveryOfDirectCostsReceivable",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_RepathaevolocumabMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Repatha (evolocumab) [Member]",
        "label": "Repatha (evolocumab) [Member]",
        "terseLabel": "Repatha (evolocumab) [Member]"
       }
      }
     },
     "localname": "RepathaevolocumabMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_RepatriationTaxOnProposedAdditionalTax": {
     "auth_ref": [],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Repatriation tax on proposed additional tax",
        "label": "Repatriation tax on proposed additional tax",
        "terseLabel": "Repatriation tax on proposed additional tax"
       }
      }
     },
     "localname": "RepatriationTaxOnProposedAdditionalTax",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/IncometaxesDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Revenue Recognition, Milestone Method, Potential Future Milestone Payments",
        "label": "Revenue Recognition, Milestone Method, Potential Future Milestone payments",
        "terseLabel": "Revenue Recognition, Milestone Method, Potential Future Milestone payments"
       }
      }
     },
     "localname": "RevenueRecognitionMilestoneMethodPotentialFutureMilestonePayments",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_ScheduleOfIntangibleAssetsTableTextBlock": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of finite-lived and indefinite-lived identifiable intangible assets.",
        "label": "Schedule Of Intangible Assets [Table Text Block]",
        "terseLabel": "Schedule of identifiable intangible assets"
       }
      }
     },
     "localname": "ScheduleOfIntangibleAssetsTableTextBlock",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "amgn_ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Schedule of Long-term Debt Instruments Exchanged [Table]",
        "label": "Schedule of Long-term Debt Instruments Exchanged [Table Text Block]",
        "terseLabel": "Schedule of long-term instruments exchanged"
       }
      }
     },
     "localname": "ScheduleOfLongTermDebtInstrumentsExchangedTableTextBlock",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "amgn_ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Schedule of Notional Amounts and Interest Rates for Cross-Currency Swaps",
        "label": "Schedule of Notional Amounts and Interest Rates for Cross-Currency Swaps [Table Text Block]",
        "terseLabel": "Schedule of notional amounts and interest rates for cross-currency swaps"
       }
      }
     },
     "localname": "ScheduleOfNotionalAmountsAndInterestRatesForCrossCurrencySwapsTableTextBlock",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "amgn_SensiparAntitrustClassActionsMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Sensipar Antitrust Class Actions [Member]",
        "label": "Sensipar Antitrust Class Actions [Member]",
        "terseLabel": "Sensipar Antitrust Class Actions [Member]"
       }
      }
     },
     "localname": "SensiparAntitrustClassActionsMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_SixPointFourZeroPercentNotesDue2039Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Six Point Four Zero Percent Notes Due 2039 [Member]",
        "label": "Six Point Four Zero Percent Notes Due 2039 [Member]",
        "terseLabel": "6.40% notes due 2039 (6.40% 2039 Notes) [Member]"
       }
      }
     },
     "localname": "SixPointFourZeroPercentNotesDue2039Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_SixPointNineZeroPercentNotesDue2038Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Six Point Nine Zero Percent Notes Due 2038 [Member]",
        "label": "Six Point Nine Zero Percent Notes Due 2038 [Member]",
        "terseLabel": "6.90% notes due 2038 (6.90% 2038 Notes) [Member]"
       }
      }
     },
     "localname": "SixPointNineZeroPercentNotesDue2038Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_SixPointThreeSevenFivePercentNotesDue2037Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Six Point Three Seven Five Percent Notes Due 2037 [Member]",
        "label": "Six Point Three Seven Five Percent Notes Due 2037 [Member]",
        "terseLabel": "6.375% notes due 2037 (6.375% 2037 Notes) [Member]"
       }
      }
     },
     "localname": "SixPointThreeSevenFivePercentNotesDue2037Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_StockRepurchaseProgramTableTextBlock": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Stock Repurchase Program [Table Text Block]",
        "label": "Stock Repurchase Program [Table Text Block]",
        "terseLabel": "Summary of activity under our stock repurchase program"
       }
      }
     },
     "localname": "StockRepurchaseProgramTableTextBlock",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "amgn_TeneobioIncMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Teneobio Inc.",
        "label": "Teneobio Inc. [Member]",
        "terseLabel": "Teneobio Inc."
       }
      }
     },
     "localname": "TeneobioIncMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_ThreePointEightSevenFivePercentNotesDue2021Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Three Point Eight Seven Five Percent Notes Due 2021 [Member]",
        "label": "Three Point Eight Seven Five Percent Notes Due 2021 [Member]",
        "terseLabel": "3.875% notes due 2021 (3.875% 2021 Notes) [Member]"
       }
      }
     },
     "localname": "ThreePointEightSevenFivePercentNotesDue2021Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_ThreePointFourFivePercentNotesDue2020Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Three Point Four Five Percent Notes Due 2020 [Member]",
        "label": "Three Point Four Five Percent Notes Due 2020 [Member]",
        "terseLabel": "3.45% notes due 2020 (3.45% 2020 Notes) [Member]"
       }
      }
     },
     "localname": "ThreePointFourFivePercentNotesDue2020Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_ThreePointOneFivePercentNotesDue2040Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Three Point One Five Percent Notes Due 2040 [Member]",
        "label": "Three Point One Five Percent Notes Due 2040 [Member]",
        "terseLabel": "3.15% notes due 2040 (3.15% 2040 Notes) [Member]"
       }
      }
     },
     "localname": "ThreePointOneFivePercentNotesDue2040Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Three Point One Two Five Percent Notes Due Two Zero Two Five [Member]",
        "label": "Three Point One Two Five Percent Notes Due Two Zero Two Five [Member]",
        "terseLabel": "3.125% notes due 2025 (3.125% 2025 Notes) [Member]"
       }
      }
     },
     "localname": "ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_ThreePointSixTwoFivePercentNotesDue2022Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Three Point Six Two Five Percent Notes Due 2022 [Member]",
        "label": "Three Point Six Two Five Percent Notes Due 2022 [Member]",
        "terseLabel": "3.625% notes due 2022 (3.625% 2022 Notes) [Member]"
       }
      }
     },
     "localname": "ThreePointSixTwoFivePercentNotesDue2022Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_ThreePointSixTwoFivePercentNotesDue2024Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Three Point Six Two Five Percent Notes Due 2024 [Member]",
        "label": "Three Point Six Two Five Percent Notes Due 2024 [Member]",
        "terseLabel": "3.625% notes due 2024 (3.625% 2024 Notes) [Member]"
       }
      }
     },
     "localname": "ThreePointSixTwoFivePercentNotesDue2024Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_ThreePointThreeSevenFivePercentNotesDue2050Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Three Point Three Seven Five Percent Notes Due 2050 [Member]",
        "label": "Three Point Three Seven Five Percent Notes Due 2050 [Member]",
        "terseLabel": "3.375% notes due 2050 (3.375% 2050 Notes) [Member]"
       }
      }
     },
     "localname": "ThreePointThreeSevenFivePercentNotesDue2050Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_ThreePointTwoZeroNotesDue2027Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Three Point Two Zero Notes Due 2027 [Member]",
        "label": "Three Point Two Zero Notes Due 2027 [Member]",
        "terseLabel": "3.20% notes due 2027 (3.20% 2027 Notes) [Member]"
       }
      }
     },
     "localname": "ThreePointTwoZeroNotesDue2027Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two Percent Euro Notes Due Two Thousand Twenty Six [Member]",
        "label": "Two Percent Euro Notes Due Two Thousand Twenty Six [Member]",
        "terseLabel": "2.00% \u20ac750 million notes due 2026 (2.00% 2026 euro Notes) [Member]",
        "verboseLabel": "2.00% 2026 euro Notes [Member]"
       }
      }
     },
     "localname": "TwoPercentEuroNotesDueTwoThousandTwentySixMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_TwoPointEightZeroPercent2041NotesMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two point eight zero percent 2041 Notes",
        "label": "Two point eight zero percent 2041 Notes [Member]",
        "terseLabel": "2.80% notes due 2041 (2.80% 2041 Notes) [Member]"
       }
      }
     },
     "localname": "TwoPointEightZeroPercent2041NotesMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_TwoPointFourFivePercentNotesDue2030Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two Point Four Five Percent Notes Due 2030 [Member]",
        "label": "Two Point Four Five Percent Notes Due 2030 [Member]",
        "terseLabel": "2.45% notes due 2030 (2.45% 2030 Notes) [Member]"
       }
      }
     },
     "localname": "TwoPointFourFivePercentNotesDue2030Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails",
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two Point One Two Five Percent Notes Due Two Zero Two Zero [Member]",
        "label": "Two Point One Two Five Percent Notes Due Two Zero Two Zero [Member]",
        "terseLabel": "2.125% notes due 2020 (2.125% 2020 Notes) [Member]"
       }
      }
     },
     "localname": "TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two Point Seven Seven Percent Notes Due Two Zero Five Three",
        "label": "Two Point Seven Seven Percent Notes Due Two Zero Five Three [Member]",
        "terseLabel": "Two Point Seven Seven Percent Notes Due Two Zero Five Three"
       }
      }
     },
     "localname": "TwoPointSevenSevenPercentNotesDueTwoZeroFiveThreeMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two Point Seven Zero Percent Notes Due Two Zero Two Two [Member]",
        "label": "Two Point Seven Zero Percent Notes Due Two Zero Two Two [Member]",
        "terseLabel": "2.70% notes due 2022 (2.70% 2022 Notes) [Member]"
       }
      }
     },
     "localname": "TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_TwoPointSixFiveNotesDue2022Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two Point Six Five Notes Due 2022 [Member]",
        "label": "Two Point Six Five Notes Due 2022 [Member]",
        "terseLabel": "2.65% notes due 2022 (2.65% 2022 Notes) [Member]"
       }
      }
     },
     "localname": "TwoPointSixFiveNotesDue2022Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two Point Six Zero Notes Due Two Zero Two Six [Member]",
        "label": "Two Point Six Zero Notes Due Two Zero Two Six [Member]",
        "terseLabel": "2.60% notes due 2026 (2.60% 2026 notes) [Member]"
       }
      }
     },
     "localname": "TwoPointSixZeroNotesDueTwoZeroTwoSixMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_TwoPointThreeZeroPercentNotesDue2031Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two Point Three Zero Percent Notes Due 2031",
        "label": "Two Point Three Zero Percent Notes Due 2031 [Member]",
        "terseLabel": "2.30% notes due 2031 (2.30% 2031 Notes) [Member]"
       }
      }
     },
     "localname": "TwoPointThreeZeroPercentNotesDue2031Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails",
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two Point Two Five Percent Notes Due Two Zero Two Three [Member]",
        "label": "Two Point Two Five Percent Notes Due Two Zero Two Three [Member]",
        "terseLabel": "2.25% notes due 2023 (2.25% 2023 Notes) [Member]"
       }
      }
     },
     "localname": "TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_TwoPointTwoZeroNotesDue2020Member": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two Point Two Zero Notes Due 2020 [Member]",
        "label": "Two Point Two Zero Notes Due 2020 [Member]",
        "terseLabel": "2.20% notes due 2020 (2.20% 2020 Notes) [Member]"
       }
      }
     },
     "localname": "TwoPointTwoZeroNotesDue2020Member",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two Point Two Zero Percent Notes Due Two Zero Two Seven [Member]",
        "label": "Two Point Two Zero Percent Notes Due Two Zero Two Seven [Member]",
        "terseLabel": "2.20% notes due 2027 (2.20% 2027 Notes) [Member]"
       }
      }
     },
     "localname": "TwoPointTwoZeroPercentNotesDueTwoZeroTwoSevenMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_TwoPointZeroPercent2032NotesMemberMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two point zero percent 2032 Notes Member",
        "label": "Two point zero percent 2032 Notes Member [Member]",
        "terseLabel": "2.00% notes due 2032 (2.00% 2032 Notes) [Member]"
       }
      }
     },
     "localname": "TwoPointZeroPercent2032NotesMemberMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_UpFrontPayment": {
     "auth_ref": [],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Up-front payment",
        "label": "Up-front payment",
        "terseLabel": "Up-front payment"
       }
      }
     },
     "localname": "UpFrontPayment",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails",
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "amgn_XgevaMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "XGEVA.",
        "label": "XGEVA [Member]",
        "terseLabel": "XGEVA\u00ae (denosumab) [Member]"
       }
      }
     },
     "localname": "XgevaMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Zero Point Forty One Percent Swiss Franc Bonds Due Two Thousand Twenty Three [Member]",
        "label": "Zero Point Forty One Percent Swiss Franc Bonds Due Two Thousand Twenty Three [Member]",
        "terseLabel": "0.41% CHF700 million bonds due 2023 (0.41% 2023 Swiss franc Bonds) [Member]",
        "verboseLabel": "0.41% 2023 Swiss franc Bonds [Member]"
       }
      }
     },
     "localname": "ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember",
     "nsuri": "http://www.amgen.com/20210930",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "country_US": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "UNITED STATES",
        "terseLabel": "US [Member]"
       }
      }
     },
     "localname": "US",
     "nsuri": "http://xbrl.sec.gov/country/2021",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "currency_AllCurrenciesDomain": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "All Currencies [Domain]",
        "terseLabel": "All Currencies [Domain]"
       }
      }
     },
     "localname": "AllCurrenciesDomain",
     "nsuri": "http://xbrl.sec.gov/currency/2021",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "currency_CHF": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Switzerland, Francs",
        "terseLabel": "Switzerland, Francs"
       }
      }
     },
     "localname": "CHF",
     "nsuri": "http://xbrl.sec.gov/currency/2021",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "currency_EUR": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Euro Member Countries, Euro",
        "terseLabel": "Euro Member Countries, Euro"
       }
      }
     },
     "localname": "EUR",
     "nsuri": "http://xbrl.sec.gov/currency/2021",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "currency_GBP": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "United Kingdom, Pounds",
        "terseLabel": "United Kingdom, Pounds"
       }
      }
     },
     "localname": "GBP",
     "nsuri": "http://xbrl.sec.gov/currency/2021",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "currency_USD": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "United States of America, Dollars",
        "terseLabel": "United States of America, Dollars"
       }
      }
     },
     "localname": "USD",
     "nsuri": "http://xbrl.sec.gov/currency/2021",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "dei_AmendmentFlag": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the XBRL content amends previously-filed or accepted submission.",
        "label": "Amendment Flag",
        "terseLabel": "Amendment Flag"
       }
      }
     },
     "localname": "AmendmentFlag",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_CityAreaCode": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Area code of city",
        "label": "City Area Code",
        "terseLabel": "City Area Code"
       }
      }
     },
     "localname": "CityAreaCode",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_CoverAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Cover page.",
        "label": "Cover [Abstract]",
        "terseLabel": "Cover [Abstract]"
       }
      }
     },
     "localname": "CoverAbstract",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "xbrltype": "stringItemType"
    },
    "dei_CurrentFiscalYearEndDate": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "End date of current fiscal year in the format --MM-DD.",
        "label": "Current Fiscal Year End Date",
        "terseLabel": "Current Fiscal Year End Date"
       }
      }
     },
     "localname": "CurrentFiscalYearEndDate",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "gMonthDayItemType"
    },
    "dei_DocumentFiscalPeriodFocus": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fiscal period values are FY, Q1, Q2, and Q3.  1st, 2nd and 3rd quarter 10-Q or 10-QT statements have value Q1, Q2, and Q3 respectively, with 10-K, 10-KT or other fiscal year statements having FY.",
        "label": "Document Fiscal Period Focus",
        "terseLabel": "Document Fiscal Period Focus"
       }
      }
     },
     "localname": "DocumentFiscalPeriodFocus",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "fiscalPeriodItemType"
    },
    "dei_DocumentFiscalYearFocus": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "This is focus fiscal year of the document report in YYYY format. For a 2006 annual report, which may also provide financial information from prior periods, fiscal 2006 should be given as the fiscal year focus. Example: 2006.",
        "label": "Document Fiscal Year Focus",
        "terseLabel": "Document Fiscal Year Focus"
       }
      }
     },
     "localname": "DocumentFiscalYearFocus",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "gYearItemType"
    },
    "dei_DocumentPeriodEndDate": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "For the EDGAR submission types of Form 8-K: the date of the report, the date of the earliest event reported; for the EDGAR submission types of Form N-1A: the filing date; for all other submission types: the end of the reporting or transition period.  The format of the date is YYYY-MM-DD.",
        "label": "Document Period End Date",
        "terseLabel": "Document Period End Date"
       }
      }
     },
     "localname": "DocumentPeriodEndDate",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "dateItemType"
    },
    "dei_DocumentQuarterlyReport": {
     "auth_ref": [
      "r611"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true only for a form used as an quarterly report.",
        "label": "Document Quarterly Report",
        "terseLabel": "Document Quarterly Report"
       }
      }
     },
     "localname": "DocumentQuarterlyReport",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_DocumentTransitionReport": {
     "auth_ref": [
      "r612"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true only for a form used as a transition report.",
        "label": "Document Transition Report",
        "terseLabel": "Document Transition Report"
       }
      }
     },
     "localname": "DocumentTransitionReport",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_DocumentType": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The type of document being provided (such as 10-K, 10-Q, 485BPOS, etc). The document type is limited to the same value as the supporting SEC submission type, or the word 'Other'.",
        "label": "Document Type",
        "terseLabel": "Document Type"
       }
      }
     },
     "localname": "DocumentType",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "submissionTypeItemType"
    },
    "dei_EntitiesTable": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Container to assemble all relevant information about each entity associated with the document instance",
        "label": "Entities [Table]",
        "terseLabel": "Entities [Table]"
       }
      }
     },
     "localname": "EntitiesTable",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "stringItemType"
    },
    "dei_EntityAddressAddressLine1": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Address Line 1 such as Attn, Building Name, Street Name",
        "label": "Entity Address, Address Line One",
        "terseLabel": "Entity Address, Address Line One"
       }
      }
     },
     "localname": "EntityAddressAddressLine1",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityAddressCityOrTown": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Name of the City or Town",
        "label": "Entity Address, City or Town",
        "terseLabel": "Entity Address, City or Town"
       }
      }
     },
     "localname": "EntityAddressCityOrTown",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityAddressPostalZipCode": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Code for the postal or zip code",
        "label": "Entity Address, Postal Zip Code",
        "terseLabel": "Entity Address, Postal Zip Code"
       }
      }
     },
     "localname": "EntityAddressPostalZipCode",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityAddressStateOrProvince": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Name of the state or province.",
        "label": "Entity Address, State or Province",
        "terseLabel": "Entity Address, State or Province"
       }
      }
     },
     "localname": "EntityAddressStateOrProvince",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "stateOrProvinceItemType"
    },
    "dei_EntityCentralIndexKey": {
     "auth_ref": [
      "r613"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "A unique 10-digit SEC-issued value to identify entities that have filed disclosures with the SEC. It is commonly abbreviated as CIK.",
        "label": "Entity Central Index Key",
        "terseLabel": "Entity Central Index Key"
       }
      }
     },
     "localname": "EntityCentralIndexKey",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "centralIndexKeyItemType"
    },
    "dei_EntityCommonStockSharesOutstanding": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Indicate number of shares or other units outstanding of each of registrant's classes of capital or common stock or other ownership interests, if and as stated on cover of related periodic report. Where multiple classes or units exist define each class/interest by adding class of stock items such as Common Class A [Member], Common Class B [Member] or Partnership Interest [Member] onto the Instrument [Domain] of the Entity Listings, Instrument.",
        "label": "Entity Common Stock, Shares Outstanding",
        "terseLabel": "Entity Common Stock, Shares Outstanding"
       }
      }
     },
     "localname": "EntityCommonStockSharesOutstanding",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "sharesItemType"
    },
    "dei_EntityCurrentReportingStatus": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Indicate 'Yes' or 'No' whether registrants (1) have filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that registrants were required to file such reports), and (2) have been subject to such filing requirements for the past 90 days. This information should be based on the registrant's current or most recent filing containing the related disclosure.",
        "label": "Entity Current Reporting Status",
        "terseLabel": "Entity Current Reporting Status"
       }
      }
     },
     "localname": "EntityCurrentReportingStatus",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "yesNoItemType"
    },
    "dei_EntityEmergingGrowthCompany": {
     "auth_ref": [
      "r613"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Indicate if registrant meets the emerging growth company criteria.",
        "label": "Entity Emerging Growth Company",
        "terseLabel": "Entity Emerging Growth Company"
       }
      }
     },
     "localname": "EntityEmergingGrowthCompany",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_EntityFileNumber": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Commission file number. The field allows up to 17 characters. The prefix may contain 1-3 digits, the sequence number may contain 1-8 digits, the optional suffix may contain 1-4 characters, and the fields are separated with a hyphen.",
        "label": "Entity File Number",
        "terseLabel": "Entity File Number"
       }
      }
     },
     "localname": "EntityFileNumber",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "fileNumberItemType"
    },
    "dei_EntityFilerCategory": {
     "auth_ref": [
      "r613"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Indicate whether the registrant is one of the following: Large Accelerated Filer, Accelerated Filer, Non-accelerated Filer. Definitions of these categories are stated in Rule 12b-2 of the Exchange Act. This information should be based on the registrant's current or most recent filing containing the related disclosure.",
        "label": "Entity Filer Category",
        "terseLabel": "Entity Filer Category"
       }
      }
     },
     "localname": "EntityFilerCategory",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "filerCategoryItemType"
    },
    "dei_EntityIncorporationStateCountryCode": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two-character EDGAR code representing the state or country of incorporation.",
        "label": "Entity Incorporation, State or Country Code",
        "terseLabel": "Entity Incorporation, State or Country Code"
       }
      }
     },
     "localname": "EntityIncorporationStateCountryCode",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "edgarStateCountryItemType"
    },
    "dei_EntityInformationLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Entity Information [Line Items]",
        "terseLabel": "Entity Information [Line Items]"
       }
      }
     },
     "localname": "EntityInformationLineItems",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "stringItemType"
    },
    "dei_EntityInteractiveDataCurrent": {
     "auth_ref": [
      "r622"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit such files).",
        "label": "Entity Interactive Data Current",
        "terseLabel": "Entity Interactive Data Current"
       }
      }
     },
     "localname": "EntityInteractiveDataCurrent",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "yesNoItemType"
    },
    "dei_EntityListingsExchangeAxis": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The axis of a table defines the relationship between the domain members or categories in the table and the line items or concepts that complete the table.",
        "label": "Entity Listings, Exchange [Axis]",
        "terseLabel": "Entity Listings, Exchange [Axis]"
       }
      }
     },
     "localname": "EntityListingsExchangeAxis",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "stringItemType"
    },
    "dei_EntityRegistrantName": {
     "auth_ref": [
      "r613"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The exact name of the entity filing the report as specified in its charter, which is required by forms filed with the SEC.",
        "label": "Entity Registrant Name",
        "terseLabel": "Entity Registrant Name"
       }
      }
     },
     "localname": "EntityRegistrantName",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityShellCompany": {
     "auth_ref": [
      "r613"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the registrant is a shell company as defined in Rule 12b-2 of the Exchange Act.",
        "label": "Entity Shell Company",
        "terseLabel": "Entity Shell Company"
       }
      }
     },
     "localname": "EntityShellCompany",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_EntitySmallBusiness": {
     "auth_ref": [
      "r613"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Indicates that the company is a Smaller Reporting Company (SRC).",
        "label": "Entity Small Business",
        "terseLabel": "Entity Small Business"
       }
      }
     },
     "localname": "EntitySmallBusiness",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_EntityTaxIdentificationNumber": {
     "auth_ref": [
      "r613"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The Tax Identification Number (TIN), also known as an Employer Identification Number (EIN), is a unique 9-digit value assigned by the IRS.",
        "label": "Entity Tax Identification Number",
        "terseLabel": "Entity Tax Identification Number"
       }
      }
     },
     "localname": "EntityTaxIdentificationNumber",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "employerIdItemType"
    },
    "dei_ExchangeDomain": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The set of all exchanges. MIC exchange codes are drawn from ISO 10383.",
        "label": "Exchange [Domain]",
        "terseLabel": "Exchange [Domain]"
       }
      }
     },
     "localname": "ExchangeDomain",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "domainItemType"
    },
    "dei_LocalPhoneNumber": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Local phone number for entity.",
        "label": "Local Phone Number",
        "terseLabel": "Local Phone Number"
       }
      }
     },
     "localname": "LocalPhoneNumber",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_Security12bTitle": {
     "auth_ref": [
      "r609"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Title of a 12(b) registered security.",
        "label": "Title of 12(b) Security",
        "terseLabel": "Title of 12(b) Security"
       }
      }
     },
     "localname": "Security12bTitle",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "securityTitleItemType"
    },
    "dei_SecurityExchangeName": {
     "auth_ref": [
      "r610"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Name of the Exchange on which a security is registered.",
        "label": "Security Exchange Name",
        "terseLabel": "Security Exchange Name"
       }
      }
     },
     "localname": "SecurityExchangeName",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "edgarExchangeCodeItemType"
    },
    "dei_TradingSymbol": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Trading symbol of an instrument as listed on an exchange.",
        "label": "Trading Symbol",
        "terseLabel": "Trading Symbol"
       }
      }
     },
     "localname": "TradingSymbol",
     "nsuri": "http://xbrl.sec.gov/dei/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "tradingSymbolItemType"
    },
    "exch_XNGS": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "NASDAQ/NGS (GLOBAL SELECT MARKET) [Member]",
        "terseLabel": "The NASDAQ Global Select Market [Member]"
       }
      }
     },
     "localname": "XNGS",
     "nsuri": "http://xbrl.sec.gov/exch/2021",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "domainItemType"
    },
    "srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember": {
     "auth_ref": [
      "r0",
      "r119",
      "r124",
      "r130",
      "r211",
      "r372",
      "r373",
      "r374",
      "r387",
      "r388",
      "r454",
      "r455",
      "r456",
      "r457",
      "r623"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Cumulative Effect, Period of Adoption, Adjustment [Member]",
        "terseLabel": "Cumulative effect of changes in accounting principles, net of tax"
       }
      }
     },
     "localname": "CumulativeEffectPeriodOfAdoptionAdjustmentMember",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "domainItemType"
    },
    "srt_CumulativeEffectPeriodOfAdoptionAxis": {
     "auth_ref": [
      "r0",
      "r119",
      "r124",
      "r130",
      "r211",
      "r372",
      "r373",
      "r374",
      "r387",
      "r388",
      "r454",
      "r455",
      "r456",
      "r457",
      "r623"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Cumulative Effect, Period of Adoption [Axis]",
        "terseLabel": "Cumulative Effect, Period of Adoption [Axis]"
       }
      }
     },
     "localname": "CumulativeEffectPeriodOfAdoptionAxis",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "stringItemType"
    },
    "srt_CumulativeEffectPeriodOfAdoptionDomain": {
     "auth_ref": [
      "r0",
      "r119",
      "r124",
      "r130",
      "r211",
      "r372",
      "r373",
      "r374",
      "r387",
      "r388",
      "r454",
      "r455",
      "r456",
      "r457",
      "r623"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Cumulative Effect, Period of Adoption [Domain]",
        "terseLabel": "Cumulative Effect, Period of Adoption [Domain]"
       }
      }
     },
     "localname": "CumulativeEffectPeriodOfAdoptionDomain",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "domainItemType"
    },
    "srt_CurrencyAxis": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Currency [Axis]",
        "terseLabel": "Currency [Axis]"
       }
      }
     },
     "localname": "CurrencyAxis",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "srt_LitigationCaseAxis": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Litigation Case [Axis]",
        "terseLabel": "Litigation Case [Axis]"
       }
      }
     },
     "localname": "LitigationCaseAxis",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "srt_LitigationCaseTypeDomain": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Litigation Case [Domain]",
        "terseLabel": "Litigation Case [Domain]"
       }
      }
     },
     "localname": "LitigationCaseTypeDomain",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "srt_MaximumMember": {
     "auth_ref": [
      "r277",
      "r317",
      "r364",
      "r367",
      "r498",
      "r499",
      "r500",
      "r501",
      "r502",
      "r503",
      "r523",
      "r565",
      "r568",
      "r607",
      "r608"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Maximum [Member]",
        "terseLabel": "Maximum [Member]"
       }
      }
     },
     "localname": "MaximumMember",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "srt_MinimumMember": {
     "auth_ref": [
      "r277",
      "r317",
      "r364",
      "r367",
      "r498",
      "r499",
      "r500",
      "r501",
      "r502",
      "r503",
      "r523",
      "r565",
      "r568",
      "r607",
      "r608"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Minimum [Member]",
        "terseLabel": "Minimum [Member]"
       }
      }
     },
     "localname": "MinimumMember",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "srt_PartnershipInterestMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Partnership Interest [Member]",
        "terseLabel": "Limited Partnership [Member]"
       }
      }
     },
     "localname": "PartnershipInterestMember",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "srt_ProductOrServiceAxis": {
     "auth_ref": [
      "r174",
      "r349",
      "r351",
      "r524",
      "r564",
      "r566"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Product and Service [Axis]",
        "terseLabel": "Product and Service [Axis]"
       }
      }
     },
     "localname": "ProductOrServiceAxis",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/RevenuesDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "srt_ProductsAndServicesDomain": {
     "auth_ref": [
      "r174",
      "r349",
      "r351",
      "r524",
      "r564",
      "r566"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Product and Service [Domain]",
        "terseLabel": "Product and Service [Domain]"
       }
      }
     },
     "localname": "ProductsAndServicesDomain",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/RevenuesDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "srt_RangeAxis": {
     "auth_ref": [
      "r277",
      "r317",
      "r354",
      "r364",
      "r367",
      "r498",
      "r499",
      "r500",
      "r501",
      "r502",
      "r503",
      "r523",
      "r565",
      "r568",
      "r607",
      "r608"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Statistical Measurement [Axis]",
        "terseLabel": "Statistical Measurement [Axis]"
       }
      }
     },
     "localname": "RangeAxis",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "srt_RangeMember": {
     "auth_ref": [
      "r277",
      "r317",
      "r354",
      "r364",
      "r367",
      "r498",
      "r499",
      "r500",
      "r501",
      "r502",
      "r503",
      "r523",
      "r565",
      "r568",
      "r607",
      "r608"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Statistical Measurement [Domain]",
        "terseLabel": "Statistical Measurement [Domain]"
       }
      }
     },
     "localname": "RangeMember",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "srt_ScenarioForecastMember": {
     "auth_ref": [
      "r125",
      "r365"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Forecast [Member]",
        "terseLabel": "Forecast [Member]"
       }
      }
     },
     "localname": "ScenarioForecastMember",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityDetailsTextualDetails",
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "srt_ScenarioUnspecifiedDomain": {
     "auth_ref": [
      "r125",
      "r130",
      "r365"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Scenario [Domain]",
        "terseLabel": "Scenario [Domain]"
       }
      }
     },
     "localname": "ScenarioUnspecifiedDomain",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityDetailsTextualDetails",
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "srt_SegmentGeographicalDomain": {
     "auth_ref": [
      "r175",
      "r176",
      "r349",
      "r352",
      "r567",
      "r598",
      "r599",
      "r600",
      "r601",
      "r602",
      "r603",
      "r604",
      "r605",
      "r606"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Geographical [Domain]",
        "terseLabel": "Geographical [Domain]"
       }
      }
     },
     "localname": "SegmentGeographicalDomain",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "srt_StatementGeographicalAxis": {
     "auth_ref": [
      "r175",
      "r176",
      "r349",
      "r352",
      "r567",
      "r594",
      "r598",
      "r599",
      "r600",
      "r601",
      "r602",
      "r603",
      "r604",
      "r605",
      "r606"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Geographical [Axis]",
        "terseLabel": "Geographical [Axis]"
       }
      }
     },
     "localname": "StatementGeographicalAxis",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "srt_StatementScenarioAxis": {
     "auth_ref": [
      "r125",
      "r130",
      "r252",
      "r365",
      "r490"
     ],
     "lang": {
      "en-us": {
       "role": {
        "label": "Scenario [Axis]",
        "terseLabel": "Scenario [Axis]"
       }
      }
     },
     "localname": "StatementScenarioAxis",
     "nsuri": "http://fasb.org/srt/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityDetailsTextualDetails",
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_AccountingPoliciesAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Accounting Policies [Abstract]",
        "terseLabel": "Accounting Policies [Abstract]"
       }
      }
     },
     "localname": "AccountingPoliciesAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_AccountsPayableCurrent": {
     "auth_ref": [
      "r34",
      "r487"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 1.0,
       "parentTag": "us-gaap_LiabilitiesCurrent",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Carrying value as of the balance sheet date of liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).",
        "label": "Accounts Payable, Current",
        "verboseLabel": "Accounts payable"
       }
      }
     },
     "localname": "AccountsPayableCurrent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AccountsReceivableNetCurrent": {
     "auth_ref": [
      "r4",
      "r16",
      "r178",
      "r179"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 3.0,
       "parentTag": "us-gaap_AssetsCurrent",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount, after allowance for credit loss, of right to consideration from customer for product sold and service rendered in normal course of business, classified as current.",
        "label": "Accounts Receivable, after Allowance for Credit Loss, Current",
        "verboseLabel": "Trade receivables, net"
       }
      }
     },
     "localname": "AccountsReceivableNetCurrent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AccruedLiabilitiesCurrent": {
     "auth_ref": [
      "r37"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 2.0,
       "parentTag": "us-gaap_LiabilitiesCurrent",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).",
        "label": "Accrued Liabilities, Current",
        "verboseLabel": "Accrued liabilities"
       }
      }
     },
     "localname": "AccruedLiabilitiesCurrent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AccruedLiabilitiesMember": {
     "auth_ref": [
      "r37"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "This item represents obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered.",
        "label": "Accrued Liabilities [Member]",
        "terseLabel": "Accrued liabilities [Member]"
       }
      }
     },
     "localname": "AccruedLiabilitiesMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment": {
     "auth_ref": [
      "r32",
      "r244"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.",
        "label": "Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment",
        "verboseLabel": "Accumulated depreciation and amortization on property, plant and equipment"
       }
      }
     },
     "localname": "AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember": {
     "auth_ref": [
      "r59",
      "r66",
      "r67",
      "r68",
      "r69",
      "r417"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Accumulated other comprehensive income (loss) from gain (loss) of derivative instrument designated and qualifying as cash flow hedge included in assessment of hedge effectiveness, attributable to parent.",
        "label": "Accumulated Gain (Loss), Net, Cash Flow Hedge, Parent [Member]",
        "verboseLabel": "Cash\u00a0flow hedges [Member]"
       }
      }
     },
     "localname": "AccumulatedGainLossNetCashFlowHedgeParentMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember": {
     "auth_ref": [
      "r53",
      "r54",
      "r55",
      "r59",
      "r66",
      "r67",
      "r68"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Accumulated unrealized gain (loss) on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), attributable to parent.",
        "label": "AOCI, Accumulated Gain (Loss), Debt Securities, Available-for-sale, Parent [Member]",
        "verboseLabel": "Available-for-sale securities [Member]"
       }
      }
     },
     "localname": "AccumulatedNetUnrealizedInvestmentGainLossMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Accumulated Other Comprehensive Income (Loss) [Line Items]",
        "terseLabel": "Accumulated Other Comprehensive Income (Loss) [Line Items]"
       }
      }
     },
     "localname": "AccumulatedOtherComprehensiveIncomeLossLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax": {
     "auth_ref": [
      "r19",
      "r57",
      "r58",
      "r59",
      "r551",
      "r573",
      "r574"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 3.0,
       "parentTag": "us-gaap_StockholdersEquity",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Accumulated change in equity from transactions and other events and circumstances from non-owner sources, net of tax effect, at period end. Excludes Net Income (Loss), and accumulated changes in equity from transactions resulting from investments by owners and distributions to owners. Includes foreign currency translation items, certain pension adjustments, unrealized gains and losses on certain investments in debt and equity securities, other than temporary impairment (OTTI) losses related to factors other than credit losses on available-for-sale and held-to-maturity debt securities that an entity does not intend to sell and it is not more likely than not that the entity will be required to sell before recovery of the amortized cost basis, as well as changes in the fair value of derivatives related to the effective portion of a designated cash flow hedge.",
        "label": "Accumulated Other Comprehensive Income (Loss), Net of Tax",
        "verboseLabel": "Accumulated other comprehensive loss"
       }
      }
     },
     "localname": "AccumulatedOtherComprehensiveIncomeLossNetOfTax",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AccumulatedOtherComprehensiveIncomeLossTable": {
     "auth_ref": [
      "r66",
      "r67",
      "r472",
      "r473",
      "r474",
      "r475",
      "r476",
      "r478"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Disclosure of information about components of accumulated other comprehensive income (loss).",
        "label": "Accumulated Other Comprehensive Income (Loss) [Table]",
        "terseLabel": "Accumulated Other Comprehensive Income (Loss) [Table]"
       }
      }
     },
     "localname": "AccumulatedOtherComprehensiveIncomeLossTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_AccumulatedOtherComprehensiveIncomeMember": {
     "auth_ref": [
      "r56",
      "r59",
      "r66",
      "r67",
      "r68",
      "r116",
      "r117",
      "r118",
      "r418",
      "r569",
      "r570",
      "r624"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Accumulated increase (decrease) in equity from transactions and other events and circumstances from non-owner sources, attributable to the parent. Excludes net income (loss), and accumulated changes in equity from transactions resulting from investments by owners and distributions to owners.",
        "label": "AOCI Attributable to Parent [Member]",
        "terseLabel": "Accumulated other comprehensive loss [Member]",
        "verboseLabel": "AOCI [Member]"
       }
      }
     },
     "localname": "AccumulatedOtherComprehensiveIncomeMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity",
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_AccumulatedTranslationAdjustmentMember": {
     "auth_ref": [
      "r51",
      "r59",
      "r66",
      "r67",
      "r68",
      "r418",
      "r473",
      "r474",
      "r475",
      "r476",
      "r478"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Accumulated other comprehensive income (loss) resulting from foreign currency translation adjustments, foreign currency transactions designated and effective as economic hedges of a net investment in a foreign entity and intra-entity foreign currency transactions that are of a long-term-investment nature, attributable to the parent.",
        "label": "Accumulated Foreign Currency Adjustment Attributable to Parent [Member]",
        "terseLabel": "Foreign currency translation [Member]"
       }
      }
     },
     "localname": "AccumulatedTranslationAdjustmentMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet": {
     "auth_ref": [],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of increase (decrease) in additional paid in capital (APIC) resulting from a tax benefit (deficiency) associated with an share-based compensation plan other than an employee stock ownership plan (ESOP).",
        "label": "Adjustment to Additional Paid in Capital, Income Tax Effect from Share-based Compensation, Net",
        "terseLabel": "Tax impact related to employee stock-based compensation expense"
       }
      }
     },
     "localname": "AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue": {
     "auth_ref": [
      "r368",
      "r369",
      "r376",
      "r377"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of increase to additional paid-in capital (APIC) for recognition of cost for award under share-based payment arrangement.",
        "label": "APIC, Share-based Payment Arrangement, Increase for Cost Recognition",
        "terseLabel": "Stock-based compensation expense"
       }
      }
     },
     "localname": "AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AlternativeInvestment": {
     "auth_ref": [
      "r460",
      "r467"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value of investment other than investment in equity security, investment in debt security and equity method investment. Includes, but is not limited to, investment in certain entities that calculate net asset value per share. Example includes, but is not limited to, investment in hedge fund, venture capital fund, private equity fund, and real estate partnership or fund.",
        "label": "Alternative Investment",
        "terseLabel": "Alternative investments"
       }
      }
     },
     "localname": "AlternativeInvestment",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AmortizationOfIntangibleAssets": {
     "auth_ref": [
      "r97",
      "r230",
      "r238"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The aggregate expense charged against earnings to allocate the cost of intangible assets (nonphysical assets not used in production) in a systematic and rational manner to the periods expected to benefit from such assets. As a noncash expense, this element is added back to net income when calculating cash provided by or used in operations using the indirect method.",
        "label": "Amortization of Intangible Assets",
        "terseLabel": "Amortization charges associated with finite-lived intangible assets"
       }
      }
     },
     "localname": "AmortizationOfIntangibleAssets",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ArrangementsAndNonarrangementTransactionsMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Collaborative arrangement and arrangement other than collaborative applicable to revenue-generating activity or operations.",
        "label": "Collaborative Arrangement and Arrangement Other than Collaborative [Domain]",
        "terseLabel": "Collaborative Arrangement and Arrangement Other than Collaborative [Domain]"
       }
      }
     },
     "localname": "ArrangementsAndNonarrangementTransactionsMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_AssetBackedSecuritiesMember": {
     "auth_ref": [
      "r193",
      "r355"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Securities that are primarily serviced by the cash flows of a discrete pool of receivables or other financial assets for example, but not limited to, credit card receivables, car loans, recreational vehicle loans, and mobile home loans.",
        "label": "Asset-backed Securities [Member]",
        "terseLabel": "Other mortgage- and asset-backed securities [Member]"
       }
      }
     },
     "localname": "AssetBackedSecuritiesMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_Assets": {
     "auth_ref": [
      "r110",
      "r163",
      "r167",
      "r172",
      "r210",
      "r263",
      "r264",
      "r265",
      "r266",
      "r267",
      "r268",
      "r269",
      "r270",
      "r271",
      "r272",
      "r273",
      "r414",
      "r419",
      "r470",
      "r485",
      "r487",
      "r529",
      "r549"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Sum of the carrying amounts as of the balance sheet date of all assets that are recognized. Assets are probable future economic benefits obtained or controlled by an entity as a result of past transactions or events.",
        "label": "Assets",
        "totalLabel": "Total assets"
       }
      }
     },
     "localname": "Assets",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AssetsAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Assets [Abstract]",
        "verboseLabel": "ASSETS"
       }
      }
     },
     "localname": "AssetsAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_AssetsCurrent": {
     "auth_ref": [
      "r5",
      "r6",
      "r47",
      "r110",
      "r210",
      "r263",
      "r264",
      "r265",
      "r266",
      "r267",
      "r268",
      "r269",
      "r270",
      "r271",
      "r272",
      "r273",
      "r414",
      "r419",
      "r470",
      "r485",
      "r487"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 1.0,
       "parentTag": "us-gaap_Assets",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Sum of the carrying amounts as of the balance sheet date of all assets that are expected to be realized in cash, sold, or consumed within one year (or the normal operating cycle, if longer). Assets are probable future economic benefits obtained or controlled by an entity as a result of past transactions or events.",
        "label": "Assets, Current",
        "totalLabel": "Total current assets"
       }
      }
     },
     "localname": "AssetsCurrent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AssetsCurrentAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Assets, Current [Abstract]",
        "verboseLabel": "Current assets:"
       }
      }
     },
     "localname": "AssetsCurrentAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_AssetsFairValueDisclosure": {
     "auth_ref": [
      "r461"
     ],
     "calculation": {
      "http://www.amgen.com/role/FairvaluemeasurementDetails": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value portion of probable future economic benefits obtained or controlled by an entity as a result of past transactions or events.",
        "label": "Assets, Fair Value Disclosure",
        "totalLabel": "Total assets"
       }
      }
     },
     "localname": "AssetsFairValueDisclosure",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AssetsFairValueDisclosureAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Assets, Fair Value Disclosure [Abstract]",
        "verboseLabel": "Assets:"
       }
      }
     },
     "localname": "AssetsFairValueDisclosureAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax": {
     "auth_ref": [
      "r187"
     ],
     "calculation": {
      "http://www.amgen.com/role/InvestmentsDetails": {
       "order": 1.0,
       "parentTag": "us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount, before tax, of unrealized gain in accumulated other comprehensive income (AOCI) on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).",
        "label": "Debt Securities, Available-for-sale, Accumulated Gross Unrealized Gain, before Tax",
        "terseLabel": "Gross unrealized gains"
       }
      }
     },
     "localname": "AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax": {
     "auth_ref": [
      "r188"
     ],
     "calculation": {
      "http://www.amgen.com/role/InvestmentsDetails": {
       "order": 2.0,
       "parentTag": "us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount, before tax, of unrealized loss in accumulated other comprehensive income (AOCI) on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).",
        "label": "Debt Securities, Available-for-sale, Accumulated Gross Unrealized Loss, before Tax",
        "negatedTerseLabel": "Gross unrealized losses"
       }
      }
     },
     "localname": "AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis": {
     "auth_ref": [
      "r185",
      "r217"
     ],
     "calculation": {
      "http://www.amgen.com/role/InvestmentsDetails": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amortized cost of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).",
        "label": "Debt Securities, Available-for-sale, Amortized Cost",
        "totalLabel": "Amortized cost"
       }
      }
     },
     "localname": "AvailableForSaleDebtSecuritiesAmortizedCostBasis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue": {
     "auth_ref": [
      "r189",
      "r191",
      "r543"
     ],
     "calculation": {
      "http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails": {
       "order": 1.0,
       "parentTag": "us-gaap_AvailableForSaleSecuritiesDebtSecurities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), with single maturity date and allocated without single maturity date, maturing in next fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).",
        "label": "Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One",
        "terseLabel": "Maturing in one year or less"
       }
      }
     },
     "localname": "AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue": {
     "auth_ref": [
      "r192",
      "r544"
     ],
     "calculation": {
      "http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails": {
       "order": 4.0,
       "parentTag": "us-gaap_AvailableForSaleSecuritiesDebtSecurities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), without single maturity date and not allocated over maturity grouping.",
        "label": "Debt Securities, Available-for-sale, Maturity, without Single Maturity Date, Fair Value",
        "terseLabel": "Residential-mortgage-backed securities"
       }
      }
     },
     "localname": "AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AvailableForSaleSecuritiesDebtSecurities": {
     "auth_ref": [
      "r181",
      "r186",
      "r217",
      "r533"
     ],
     "calculation": {
      "http://www.amgen.com/role/FairvaluemeasurementDetails": {
       "order": 1.0,
       "parentTag": "us-gaap_AssetsFairValueDisclosure",
       "weight": 1.0
      },
      "http://www.amgen.com/role/InvestmentsDetails": {
       "order": 3.0,
       "parentTag": "us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis",
       "weight": 1.0
      },
      "http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      },
      "http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).",
        "label": "Debt Securities, Available-for-sale",
        "terseLabel": "Fair values",
        "totalLabel": "Total interest-bearing securities",
        "verboseLabel": "Interest-bearing securities"
       }
      }
     },
     "localname": "AvailableForSaleSecuritiesDebtSecurities",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsDetails",
      "http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails",
      "http://www.amgen.com/role/InvestmentsFairValuesbyContractualMaturityDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent": {
     "auth_ref": [
      "r183",
      "r217"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 2.0,
       "parentTag": "us-gaap_AssetsCurrent",
       "weight": 1.0
      },
      "http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails": {
       "order": 2.0,
       "parentTag": "us-gaap_AvailableForSaleSecuritiesDebtSecurities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), classified as current.",
        "label": "Debt Securities, Available-for-sale, Current",
        "verboseLabel": "Marketable securities"
       }
      }
     },
     "localname": "AvailableForSaleSecuritiesDebtSecuritiesCurrent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets",
      "http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_BalanceSheetLocationAxis": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by location on balance sheet (statement of financial position).",
        "label": "Balance Sheet Location [Axis]",
        "terseLabel": "Balance Sheet Location [Axis]"
       }
      }
     },
     "localname": "BalanceSheetLocationAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_BalanceSheetLocationDomain": {
     "auth_ref": [
      "r428",
      "r433"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Location in the balance sheet (statement of financial position).",
        "label": "Balance Sheet Location [Domain]",
        "terseLabel": "Balance Sheet Location [Domain]"
       }
      }
     },
     "localname": "BalanceSheetLocationDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_BusinessAcquisitionAcquireeDomain": {
     "auth_ref": [
      "r363",
      "r366"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Identification of the acquiree in a material business combination (or series of individually immaterial business combinations), which may include the name or other type of identification of the acquiree.",
        "label": "Business Acquisition, Acquiree [Domain]",
        "terseLabel": "Business Acquisition, Acquiree [Domain]"
       }
      }
     },
     "localname": "BusinessAcquisitionAcquireeDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails",
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_BusinessAcquisitionAxis": {
     "auth_ref": [
      "r363",
      "r366",
      "r396",
      "r397"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by business combination or series of individually immaterial business combinations.",
        "label": "Business Acquisition [Axis]",
        "terseLabel": "Business Acquisition [Axis]"
       }
      }
     },
     "localname": "BusinessAcquisitionAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails",
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_BusinessAcquisitionLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Business Acquisition [Line Items]",
        "terseLabel": "Business Acquisition [Line Items]"
       }
      }
     },
     "localname": "BusinessAcquisitionLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_BusinessCombinationAndAssetAcquisitionAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Business Combination and Asset Acquisition [Abstract]"
       }
      }
     },
     "localname": "BusinessCombinationAndAssetAcquisitionAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh": {
     "auth_ref": [
      "r406"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "For contingent consideration arrangements recognized in connection with a business combination, this element represents an estimate of the high-end of the potential range (undiscounted) of the consideration which may be paid.",
        "label": "Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, High",
        "terseLabel": "Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, High"
       }
      }
     },
     "localname": "BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_BusinessCombinationContingentConsiderationLiability": {
     "auth_ref": [
      "r402",
      "r403",
      "r405"
     ],
     "calculation": {
      "http://www.amgen.com/role/FairvaluemeasurementDetails": {
       "order": 3.0,
       "parentTag": "us-gaap_LiabilitiesFairValueDisclosure",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of liability recognized arising from contingent consideration in a business combination.",
        "label": "Business Combination, Contingent Consideration, Liability",
        "verboseLabel": "Contingent consideration obligations"
       }
      }
     },
     "localname": "BusinessCombinationContingentConsiderationLiability",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_BusinessCombinationDisclosureTextBlock": {
     "auth_ref": [
      "r407"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure for a business combination (or series of individually immaterial business combinations) completed during the period, including background, timing, and recognized assets and liabilities. The disclosure may include leverage buyout transactions (as applicable).",
        "label": "Business Combination Disclosure [Text Block]",
        "terseLabel": "Business Combination Disclosure [Text Block]"
       }
      }
     },
     "localname": "BusinessCombinationDisclosureTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitions"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther": {
     "auth_ref": [
      "r398"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of other liabilities due within one year or within the normal operating cycle, if longer, assumed at the acquisition date.",
        "label": "Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Liabilities, Other",
        "terseLabel": "Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Liabilities, Other"
       }
      }
     },
     "localname": "BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets": {
     "auth_ref": [
      "r398"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of deferred tax asset attributable to deductible temporary differences and carryforwards acquired at the acquisition date.",
        "label": "Business Combination Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Assets",
        "terseLabel": "Business Combination Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Assets"
       }
      }
     },
     "localname": "BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssets",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities": {
     "auth_ref": [
      "r398"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of deferred tax liability attributable to taxable temporary differences assumed at the acquisition date.",
        "label": "Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Liabilities",
        "terseLabel": "Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Liabilities"
       }
      }
     },
     "localname": "BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_Cash": {
     "auth_ref": [
      "r29",
      "r487",
      "r576",
      "r577"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Excludes cash and cash equivalents within disposal group and discontinued operation.",
        "label": "Cash",
        "verboseLabel": "Cash"
       }
      }
     },
     "localname": "Cash",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsAvailableforsaleInvestmentsDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_CashAndCashEquivalentsAtCarryingValue": {
     "auth_ref": [
      "r2",
      "r29",
      "r99"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 1.0,
       "parentTag": "us-gaap_AssetsCurrent",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation.",
        "label": "Cash and Cash Equivalents, at Carrying Value",
        "verboseLabel": "Cash and cash equivalents"
       }
      }
     },
     "localname": "CashAndCashEquivalentsAtCarryingValue",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_CashAndCashEquivalentsFairValueDisclosure": {
     "auth_ref": [],
     "calculation": {
      "http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails": {
       "order": 1.0,
       "parentTag": "us-gaap_AvailableForSaleSecuritiesDebtSecurities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value portion of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates.",
        "label": "Cash and Cash Equivalents, Fair Value Disclosure",
        "terseLabel": "Cash and cash equivalents"
       }
      }
     },
     "localname": "CashAndCashEquivalentsFairValueDisclosure",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents": {
     "auth_ref": [
      "r94",
      "r99",
      "r103"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of cash and cash equivalents, and cash and cash equivalents restricted to withdrawal or usage. Excludes amount for disposal group and discontinued operations. Cash includes, but is not limited to, currency on hand, demand deposits with banks or financial institutions, and other accounts with general characteristics of demand deposits. Cash equivalents include, but are not limited to, short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates.",
        "label": "Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents",
        "periodEndLabel": "Cash and cash equivalents at end of period",
        "periodStartLabel": "Cash and cash equivalents at beginning of period"
       }
      }
     },
     "localname": "CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect": {
     "auth_ref": [
      "r94",
      "r471"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of increase (decrease) in cash, cash equivalents, and cash and cash equivalents restricted to withdrawal or usage; including effect from exchange rate change. Cash includes, but is not limited to, currency on hand, demand deposits with banks or financial institutions, and other accounts with general characteristics of demand deposits. Cash equivalents include, but are not limited to, short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates.",
        "label": "Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect",
        "totalLabel": "Increase in cash and cash equivalents"
       }
      }
     },
     "localname": "CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_CashFlowHedgingMember": {
     "auth_ref": [
      "r425"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Hedge of the exposure to variability in the cash flows of a recognized asset or liability, or of a forecasted transaction, that is attributable to a particular risk.",
        "label": "Cash Flow Hedging [Member]",
        "terseLabel": "Cash flow hedge [Member]",
        "verboseLabel": "Cash flow hedges [Member]"
       }
      }
     },
     "localname": "CashFlowHedgingMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1": {
     "auth_ref": [
      "r449"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of gain (loss) from the increase (decrease) in fair value of derivative and nonderivative instruments designated as fair value hedging instruments recognized in the income statement.",
        "label": "Change in Unrealized Gain (Loss) on Fair Value Hedging Instruments",
        "terseLabel": "Gains (losses) on fair value hedging relationships, Derivatives designated as hedging instruments"
       }
      }
     },
     "localname": "ChangeInUnrealizedGainLossOnFairValueHedgingInstruments1",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1": {
     "auth_ref": [
      "r449"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of the increase (decrease) in fair value of the hedged item in a fair value hedge recognized in the income statement.",
        "label": "Change in Unrealized Gain (Loss) on Hedged Item in Fair Value Hedge",
        "terseLabel": "Gains (losses) on fair value hedging relationships, Hedged items"
       }
      }
     },
     "localname": "ChangeInUnrealizedGainLossOnHedgedItemInFairValueHedge1",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ClassOfStockDomain": {
     "auth_ref": [
      "r107",
      "r110",
      "r133",
      "r134",
      "r135",
      "r137",
      "r139",
      "r147",
      "r148",
      "r149",
      "r210",
      "r263",
      "r267",
      "r268",
      "r269",
      "r272",
      "r273",
      "r315",
      "r316",
      "r320",
      "r324",
      "r470",
      "r614"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Share of stock differentiated by the voting rights the holder receives. Examples include, but are not limited to, common stock, redeemable preferred stock, nonredeemable preferred stock, and convertible stock.",
        "label": "Class of Stock [Domain]",
        "terseLabel": "Class of Stock [Domain]"
       }
      }
     },
     "localname": "ClassOfStockDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_ClassOfStockLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Class of Stock [Line Items]",
        "terseLabel": "Class of Stock [Line Items]"
       }
      }
     },
     "localname": "ClassOfStockLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityDetailsTextualDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_CollaborativeArrangementDisclosureTextBlock": {
     "auth_ref": [
      "r408",
      "r409",
      "r411"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure for collaborative arrangements in which the entity is a participant, including a) information about the nature and purpose of such arrangements; b) its rights and obligations thereunder; c) the accounting policy for collaborative arrangements; and d) the income statement classification and amounts attributable to transactions arising from the collaborative arrangement between participants.",
        "label": "Collaborative Arrangement Disclosure [Text Block]",
        "terseLabel": "Collaborations"
       }
      }
     },
     "localname": "CollaborativeArrangementDisclosureTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/Collaborations"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]",
        "terseLabel": "Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]"
       }
      }
     },
     "localname": "CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_CommitmentsAndContingencies": {
     "auth_ref": [
      "r42",
      "r251",
      "r534",
      "r555"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 6.0,
       "parentTag": "us-gaap_LiabilitiesAndStockholdersEquity",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Represents the caption on the face of the balance sheet to indicate that the entity has entered into (1) purchase or supply arrangements that will require expending a portion of its resources to meet the terms thereof, and (2) is exposed to potential losses or, less frequently, gains, arising from (a) possible claims against a company's resources due to future performance under contract terms, and (b) possible losses or likely gains from uncertainties that will ultimately be resolved when one or more future events that are deemed likely to occur do occur or fail to occur.",
        "label": "Commitments and Contingencies",
        "verboseLabel": "Contingencies and commitments"
       }
      }
     },
     "localname": "CommitmentsAndContingencies",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_CommitmentsAndContingenciesDisclosureAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Commitments and Contingencies Disclosure [Abstract]",
        "terseLabel": "Commitments and Contingencies Disclosure [Abstract]"
       }
      }
     },
     "localname": "CommitmentsAndContingenciesDisclosureAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_CommitmentsAndContingenciesDisclosureTextBlock": {
     "auth_ref": [
      "r248",
      "r249",
      "r250",
      "r259",
      "r595"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure for commitments and contingencies.",
        "label": "Commitments and Contingencies Disclosure [Text Block]",
        "verboseLabel": "Contingencies and commitments"
       }
      }
     },
     "localname": "CommitmentsAndContingenciesDisclosureTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/Contingenciesandcommitments"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_CommonStockDividendsPerShareCashPaid": {
     "auth_ref": [
      "r338"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Aggregate dividends paid during the period for each share of common stock outstanding.",
        "label": "Common Stock, Dividends, Per Share, Cash Paid",
        "terseLabel": "Dividends paid per share (in usd per share)"
       }
      }
     },
     "localname": "CommonStockDividendsPerShareCashPaid",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityDetailsTextualDetails"
     ],
     "xbrltype": "perShareItemType"
    },
    "us-gaap_CommonStockDividendsPerShareDeclared": {
     "auth_ref": [
      "r338"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Aggregate dividends declared during the period for each share of common stock outstanding.",
        "label": "Common Stock, Dividends, Per Share, Declared",
        "terseLabel": "Common stock, dividends declared per share (in usd per share)",
        "verboseLabel": "Dividends declared per share (in usd per share)"
       }
      }
     },
     "localname": "CommonStockDividendsPerShareDeclared",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquityParenthetical",
      "http://www.amgen.com/role/StockholdersequityDetailsTextualDetails"
     ],
     "xbrltype": "perShareItemType"
    },
    "us-gaap_CommonStockIncludingAdditionalPaidInCapitalMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Common stock held by shareholders with par value plus amounts in excess of par value or issuance value (in cases of no-par value stock).",
        "label": "Common Stock Including Additional Paid in Capital [Member]",
        "terseLabel": "Common stock and additional paid-in capital [Member]"
       }
      }
     },
     "localname": "CommonStockIncludingAdditionalPaidInCapitalMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_CommonStockMember": {
     "auth_ref": [
      "r116",
      "r117",
      "r456"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Stock that is subordinate to all other stock of the issuer.",
        "label": "Common Stock [Member]",
        "terseLabel": "Common Stock [Member]",
        "verboseLabel": "Number of shares of common stock [Member]"
       }
      }
     },
     "localname": "CommonStockMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity",
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_CommonStockParOrStatedValuePerShare": {
     "auth_ref": [
      "r15"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Face amount or stated value per share of common stock.",
        "label": "Common Stock, Par or Stated Value Per Share",
        "verboseLabel": "Common stock and additional paid-in capital, par value (in usd per share)"
       }
      }
     },
     "localname": "CommonStockParOrStatedValuePerShare",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheetsParenthetical"
     ],
     "xbrltype": "perShareItemType"
    },
    "us-gaap_CommonStockSharesAuthorized": {
     "auth_ref": [
      "r15"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The maximum number of common shares permitted to be issued by an entity's charter and bylaws.",
        "label": "Common Stock, Shares Authorized",
        "verboseLabel": "Common stock and additional paid-in capital, shares authorized"
       }
      }
     },
     "localname": "CommonStockSharesAuthorized",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheetsParenthetical"
     ],
     "xbrltype": "sharesItemType"
    },
    "us-gaap_CommonStockSharesOutstanding": {
     "auth_ref": [
      "r15",
      "r331"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Number of shares of common stock outstanding. Common stock represent the ownership interest in a corporation.",
        "label": "Common Stock, Shares, Outstanding",
        "periodEndLabel": "Ending Balance, Shares",
        "periodStartLabel": "Beginning Balance, Shares",
        "verboseLabel": "Common stock and additional paid-in capital, shares outstanding"
       }
      }
     },
     "localname": "CommonStockSharesOutstanding",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheetsParenthetical",
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "sharesItemType"
    },
    "us-gaap_CommonStocksIncludingAdditionalPaidInCapital": {
     "auth_ref": [
      "r15",
      "r17",
      "r338"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 1.0,
       "parentTag": "us-gaap_StockholdersEquity",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of par value plus amounts in excess of par value or issuance value for common stock issued.",
        "label": "Common Stocks, Including Additional Paid in Capital",
        "verboseLabel": "Common stock and additional paid-in capital; $0.0001 par value; 2,750.0 shares authorized; outstanding\u2014565.0 shares in 2021 and 578.3 shares in 2020"
       }
      }
     },
     "localname": "CommonStocksIncludingAdditionalPaidInCapital",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ComprehensiveIncomeNetOfTax": {
     "auth_ref": [
      "r62",
      "r64",
      "r65",
      "r73",
      "r538",
      "r559"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount after tax of increase (decrease) in equity from transactions and other events and circumstances from net income and other comprehensive income, attributable to parent entity. Excludes changes in equity resulting from investments by owners and distributions to owners.",
        "label": "Comprehensive Income (Loss), Net of Tax, Attributable to Parent",
        "totalLabel": "Comprehensive income"
       }
      }
     },
     "localname": "ComprehensiveIncomeNetOfTax",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ConsolidationPolicyTextBlock": {
     "auth_ref": [
      "r105",
      "r416"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Disclosure of accounting policy regarding (1) the principles it follows in consolidating or combining the separate financial statements, including the principles followed in determining the inclusion or exclusion of subsidiaries or other entities in the consolidated or combined financial statements and (2) its treatment of interests (for example, common stock, a partnership interest or other means of exerting influence) in other entities, for example consolidation or use of the equity or cost methods of accounting.  The accounting policy may also address the accounting treatment for intercompany accounts and transactions, noncontrolling interest, and the income statement treatment in consolidation for issuances of stock by a subsidiary.",
        "label": "Consolidation, Policy [Policy Text Block]",
        "verboseLabel": "Principles of consolidation"
       }
      }
     },
     "localname": "ConsolidationPolicyTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesPolicies"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_CostOfGoodsAndServicesSold": {
     "auth_ref": [
      "r76",
      "r524"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome": {
       "order": 1.0,
       "parentTag": "us-gaap_CostsAndExpenses",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The aggregate costs related to goods produced and sold and services rendered by an entity during the reporting period. This excludes costs incurred during the reporting period related to financial services rendered and other revenue generating activities.",
        "label": "Cost of Goods and Services Sold",
        "terseLabel": "Cost of sales"
       }
      }
     },
     "localname": "CostOfGoodsAndServicesSold",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_CostsAndExpenses": {
     "auth_ref": [
      "r75"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome": {
       "order": 2.0,
       "parentTag": "us-gaap_OperatingIncomeLoss",
       "weight": -1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Total costs of sales and operating expenses for the period.",
        "label": "Costs and Expenses",
        "totalLabel": "Total operating expenses"
       }
      }
     },
     "localname": "CostsAndExpenses",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_CostsAndExpensesAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Costs and Expenses [Abstract]",
        "verboseLabel": "Operating expenses:"
       }
      }
     },
     "localname": "CostsAndExpensesAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_DebtDisclosureAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Debt Disclosure [Abstract]",
        "terseLabel": "Debt Disclosure [Abstract]"
       }
      }
     },
     "localname": "DebtDisclosureAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_DebtDisclosureTextBlock": {
     "auth_ref": [
      "r106",
      "r280",
      "r281",
      "r282",
      "r283",
      "r284",
      "r285",
      "r286",
      "r291",
      "r298",
      "r299",
      "r301",
      "r311"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure for information about short-term and long-term debt arrangements, which includes amounts of borrowings under each line of credit, note payable, commercial paper issue, bonds indenture, debenture issue, own-share lending arrangements and any other contractual agreement to repay funds, and about the underlying arrangements, rationale for a classification as long-term, including repayment terms, interest rates, collateral provided, restrictions on use of assets and activities, whether or not in compliance with debt covenants, and other matters important to users of the financial statements, such as the effects of refinancing and noncompliance with debt covenants.",
        "label": "Debt Disclosure [Text Block]",
        "verboseLabel": "Financing arrangements"
       }
      }
     },
     "localname": "DebtDisclosureTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/Financingarrangements"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_DebtInstrumentAxis": {
     "auth_ref": [
      "r10",
      "r11",
      "r12",
      "r109",
      "r114",
      "r274",
      "r275",
      "r276",
      "r277",
      "r278",
      "r279",
      "r281",
      "r287",
      "r288",
      "r289",
      "r290",
      "r292",
      "r293",
      "r294",
      "r295",
      "r296",
      "r297",
      "r307",
      "r308",
      "r309",
      "r310",
      "r483",
      "r530",
      "r531",
      "r548"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by type of debt instrument, including, but not limited to, draws against credit facilities.",
        "label": "Debt Instrument [Axis]",
        "terseLabel": "Debt Instrument [Axis]"
       }
      }
     },
     "localname": "DebtInstrumentAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails",
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_DebtInstrumentCarryingAmount": {
     "auth_ref": [
      "r12",
      "r302",
      "r531",
      "r548"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount, before unamortized (discount) premium and debt issuance costs, of long-term debt. Includes, but is not limited to, notes payable, bonds payable, commercial loans, mortgage loans, convertible debt, subordinated debt and other types of debt.",
        "label": "Long-term Debt, Gross",
        "terseLabel": "Long-term debt, gross"
       }
      }
     },
     "localname": "DebtInstrumentCarryingAmount",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_DebtInstrumentFaceAmount": {
     "auth_ref": [
      "r274",
      "r307",
      "r308",
      "r481",
      "r483",
      "r484"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Face (par) amount of debt instrument at time of issuance.",
        "label": "Debt Instrument, Face Amount",
        "terseLabel": "Face amount"
       }
      }
     },
     "localname": "DebtInstrumentFaceAmount",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_DebtInstrumentInterestRateEffectivePercentage": {
     "auth_ref": [
      "r39",
      "r305",
      "r481",
      "r483"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Effective interest rate for the funds borrowed under the debt agreement considering interest compounding and original issue discount or premium.",
        "label": "Debt Instrument, Interest Rate, Effective Percentage",
        "terseLabel": "Effective interest rate"
       }
      }
     },
     "localname": "DebtInstrumentInterestRateEffectivePercentage",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual"
     ],
     "xbrltype": "percentItemType"
    },
    "us-gaap_DebtInstrumentInterestRateStatedPercentage": {
     "auth_ref": [
      "r39",
      "r275"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Contractual interest rate for funds borrowed, under the debt agreement.",
        "label": "Debt Instrument, Interest Rate, Stated Percentage",
        "terseLabel": "Interest rate, stated percentage"
       }
      }
     },
     "localname": "DebtInstrumentInterestRateStatedPercentage",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails",
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "percentItemType"
    },
    "us-gaap_DebtInstrumentLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Debt Instrument [Line Items]",
        "terseLabel": "Debt Instrument [Line Items]"
       }
      }
     },
     "localname": "DebtInstrumentLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails",
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_DebtInstrumentNameDomain": {
     "auth_ref": [
      "r40",
      "r109",
      "r114",
      "r274",
      "r275",
      "r276",
      "r277",
      "r278",
      "r279",
      "r281",
      "r287",
      "r288",
      "r289",
      "r290",
      "r292",
      "r293",
      "r294",
      "r295",
      "r296",
      "r297",
      "r307",
      "r308",
      "r309",
      "r310",
      "r483"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The name for the particular debt instrument or borrowing that distinguishes it from other debt instruments or borrowings, including draws against credit facilities.",
        "label": "Debt Instrument, Name [Domain]",
        "terseLabel": "Debt Instrument, Name [Domain]"
       }
      }
     },
     "localname": "DebtInstrumentNameDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails",
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_DebtInstrumentTable": {
     "auth_ref": [
      "r40",
      "r109",
      "r114",
      "r274",
      "r275",
      "r276",
      "r277",
      "r278",
      "r279",
      "r281",
      "r287",
      "r288",
      "r289",
      "r290",
      "r292",
      "r293",
      "r294",
      "r295",
      "r296",
      "r297",
      "r300",
      "r307",
      "r308",
      "r309",
      "r310",
      "r332",
      "r335",
      "r336",
      "r337",
      "r480",
      "r481",
      "r483",
      "r484",
      "r547"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "A table or schedule providing information pertaining to long-term debt instruments or arrangements, including identification, terms, features, collateral requirements and other information necessary to a fair presentation. These are debt arrangements that originally required repayment more than twelve months after issuance or greater than the normal operating cycle of the company, if longer.",
        "label": "Schedule of Long-term Debt Instruments [Table]",
        "terseLabel": "Schedule of Long-term Debt Instruments [Table]"
       }
      }
     },
     "localname": "DebtInstrumentTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails",
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet": {
     "auth_ref": [
      "r287",
      "r303",
      "r307",
      "r308",
      "r482"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of unamortized debt discount (premium) and debt issuance costs.",
        "label": "Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net",
        "negatedLabel": "Unamortized bond discounts, premiums and issuance costs, net"
       }
      }
     },
     "localname": "DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_DebtSecuritiesAvailableForSaleRealizedGain": {
     "auth_ref": [
      "r198"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of realized gain on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).",
        "label": "Debt Securities, Available-for-sale, Realized Gain",
        "verboseLabel": "Total realized gains"
       }
      }
     },
     "localname": "DebtSecuritiesAvailableForSaleRealizedGain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsAvailableforsaleInvestmentsDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss": {
     "auth_ref": [
      "r198"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of realized loss on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).",
        "label": "Debt Securities, Available-for-sale, Realized Loss",
        "verboseLabel": "Total realized losses"
       }
      }
     },
     "localname": "DebtSecuritiesAvailableForSaleRealizedLoss",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsAvailableforsaleInvestmentsDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_DebtSecuritiesAvailableForSaleTable": {
     "auth_ref": [
      "r200"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Disclosure of information about investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).",
        "label": "Debt Securities, Available-for-sale [Table]",
        "terseLabel": "Debt Securities, Available-for-sale [Table]"
       }
      }
     },
     "localname": "DebtSecuritiesAvailableForSaleTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock": {
     "auth_ref": [
      "r200"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).",
        "label": "Debt Securities, Available-for-sale [Table Text Block]",
        "terseLabel": "Amortized cost, gross unrealized gains, gross unrealized losses and estimated fair values of available-for-sale investments by type of security"
       }
      }
     },
     "localname": "DebtSecuritiesAvailableForSaleTableTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_DebtSecuritiesPayableMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Financial obligations in a security form.",
        "label": "Debt Securities Payable [Member]",
        "terseLabel": "Debt Securities Payable [Member]"
       }
      }
     },
     "localname": "DebtSecuritiesPayableMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_DeferredIncomeTaxesAndTaxCredits": {
     "auth_ref": [
      "r98"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 3.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of deferred income tax expense (benefit) and income tax credits.",
        "label": "Deferred Income Taxes and Tax Credits",
        "terseLabel": "Deferred income taxes"
       }
      }
     },
     "localname": "DeferredIncomeTaxesAndTaxCredits",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_DepreciationDepletionAndAmortization": {
     "auth_ref": [
      "r97",
      "r160"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 2.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The aggregate expense recognized in the current period that allocates the cost of tangible assets, intangible assets, or depleting assets to periods that benefit from use of the assets.",
        "label": "Depreciation, Depletion and Amortization",
        "verboseLabel": "Depreciation, amortization and other"
       }
      }
     },
     "localname": "DepreciationDepletionAndAmortization",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_DerivativeAssetFairValueNetAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Derivative Asset, Fair Value, Amount Not Offset Against Collateral [Abstract]",
        "verboseLabel": "Assets"
       }
      }
     },
     "localname": "DerivativeAssetFairValueNetAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_DerivativeBasisSpreadOnVariableRate": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The percentage points added to the reference rate to compute the variable rate on the interest rate derivative.",
        "label": "Derivative, Basis Spread on Variable Rate",
        "terseLabel": "Derivative, Basis Spread on Variable Rate"
       }
      }
     },
     "localname": "DerivativeBasisSpreadOnVariableRate",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "percentItemType"
    },
    "us-gaap_DerivativeContractTypeDomain": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Financial instrument or contract with one or more underlyings, notional amount or payment provision or both, and the contract can be net settled by means outside the contract or delivery of an asset.",
        "label": "Derivative Contract [Domain]",
        "terseLabel": "Derivative Contract [Domain]"
       }
      }
     },
     "localname": "DerivativeContractTypeDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_DerivativeFairValueOfDerivativeAsset": {
     "auth_ref": [
      "r48",
      "r49",
      "r50",
      "r431",
      "r505"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value, before effects of master netting arrangements, of a financial asset or other contract with one or more underlyings, notional amount or payment provision or both, and the contract can be net settled by means outside the contract or delivery of an asset. Includes assets elected not to be offset. Excludes assets not subject to a master netting arrangement.",
        "label": "Derivative Asset, Fair Value, Gross Asset",
        "terseLabel": "Total derivative assets, fair value"
       }
      }
     },
     "localname": "DerivativeFairValueOfDerivativeAsset",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_DerivativeFairValueOfDerivativeLiability": {
     "auth_ref": [
      "r48",
      "r49",
      "r50",
      "r431",
      "r505"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value, before effects of master netting arrangements, of a financial liability or contract with one or more underlyings, notional amount or payment provision or both, and the contract can be net settled by means outside the contract or delivery of an asset. Includes liabilities elected not to be offset. Excludes liabilities not subject to a master netting arrangement.",
        "label": "Derivative Liability, Fair Value, Gross Liability",
        "terseLabel": "Total derivative liabilities, fair value"
       }
      }
     },
     "localname": "DerivativeFairValueOfDerivativeLiability",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_DerivativeFixedInterestRate": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fixed interest rate related to the interest rate derivative.",
        "label": "Derivative, Fixed Interest Rate",
        "verboseLabel": "Interest rates"
       }
      }
     },
     "localname": "DerivativeFixedInterestRate",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails"
     ],
     "xbrltype": "percentItemType"
    },
    "us-gaap_DerivativeInstrumentRiskAxis": {
     "auth_ref": [
      "r49",
      "r429",
      "r432",
      "r437",
      "r441"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by type of derivative contract.",
        "label": "Derivative Instrument [Axis]",
        "terseLabel": "Derivative Instrument [Axis]"
       }
      }
     },
     "localname": "DerivativeInstrumentRiskAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Derivative Instruments and Hedging Activities Disclosure [Abstract]",
        "terseLabel": "Derivative Instruments and Hedging Activities Disclosure [Abstract]"
       }
      }
     },
     "localname": "DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock": {
     "auth_ref": [
      "r453",
      "r459"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure for derivative instruments and hedging activities including, but not limited to, risk management strategies, non-hedging derivative instruments, assets, liabilities, revenue and expenses, and methodologies and assumptions used in determining the amounts.",
        "label": "Derivative Instruments and Hedging Activities Disclosure [Text Block]",
        "verboseLabel": "Derivative instruments"
       }
      }
     },
     "localname": "DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/Derivativeinstruments"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis": {
     "auth_ref": [
      "r426",
      "r429",
      "r437"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by type of hedging relationship.",
        "label": "Hedging Relationship [Axis]",
        "terseLabel": "Hedging Relationship [Axis]"
       }
      }
     },
     "localname": "DerivativeInstrumentsGainLossByHedgingRelationshipAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable": {
     "auth_ref": [
      "r426",
      "r429",
      "r437",
      "r441",
      "r442",
      "r448",
      "r450"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Disclosure of information about the location and amount of derivative instruments and nonderivative instruments designated as hedging instruments reported before netting adjustments, and the amount of gain (loss) on derivative instruments and nonderivative instruments designated and qualified as hedging instruments.",
        "label": "Derivative Instruments, Gain (Loss) [Table]",
        "terseLabel": "Derivative Instruments, Gain (Loss) [Table]"
       }
      }
     },
     "localname": "DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_DerivativeInstrumentsGainLossLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Derivative Instruments, Gain (Loss) [Line Items]",
        "terseLabel": "Derivative Instruments, Gain (Loss) [Line Items]"
       }
      }
     },
     "localname": "DerivativeInstrumentsGainLossLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_DerivativeLiabilityFairValueNetAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Derivative Liability, Fair Value, Amount Not Offset Against Collateral [Abstract]",
        "verboseLabel": "Liabilities"
       }
      }
     },
     "localname": "DerivativeLiabilityFairValueNetAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_DerivativeLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Derivative [Line Items]",
        "terseLabel": "Derivative [Line Items]"
       }
      }
     },
     "localname": "DerivativeLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_DerivativeNotionalAmount": {
     "auth_ref": [
      "r422",
      "r424"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Nominal or face amount used to calculate payment on derivative.",
        "label": "Derivative, Notional Amount",
        "terseLabel": "Notional amounts",
        "verboseLabel": "Derivative, notional amount"
       }
      }
     },
     "localname": "DerivativeNotionalAmount",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_DerivativeTable": {
     "auth_ref": [
      "r421",
      "r423",
      "r424",
      "r426",
      "r427",
      "r434",
      "r437",
      "r446",
      "r447",
      "r450",
      "r453"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Schedule that describes and identifies a derivative or group of derivatives on a disaggregated basis, such as for individual instruments, or small groups of similar instruments. May include a combination of the type of instrument, risks being hedged, notional amount, hedge designation, related hedged item, inception date, maturity date, or other relevant item.",
        "label": "Derivative [Table]",
        "terseLabel": "Derivative [Table]"
       }
      }
     },
     "localname": "DerivativeTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_DerivativesFairValueLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Derivatives, Fair Value [Line Items]",
        "terseLabel": "Derivatives Fair Value [Line Items]"
       }
      }
     },
     "localname": "DerivativesFairValueLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_DesignatedAsHedgingInstrumentMember": {
     "auth_ref": [
      "r426"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Derivative instrument designated as hedging instrument under Generally Accepted Accounting Principles (GAAP).",
        "label": "Designated as Hedging Instrument [Member]",
        "verboseLabel": "Derivatives designated as hedging instrument [Member]"
       }
      }
     },
     "localname": "DesignatedAsHedgingInstrumentMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_DevelopedTechnologyRightsMember": {
     "auth_ref": [
      "r401"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Rights to developed technology, which can include the right to develop, use, market, sell, or offer for sale products, compounds, or intellectual property.",
        "label": "Developed Technology Rights [Member]",
        "verboseLabel": "Developed-Product-Technology Rights [Member]"
       }
      }
     },
     "localname": "DevelopedTechnologyRightsMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_DisaggregationOfRevenueTableTextBlock": {
     "auth_ref": [
      "r349"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of disaggregation of revenue into categories depicting how nature, amount, timing, and uncertainty of revenue and cash flows are affected by economic factor.",
        "label": "Disaggregation of Revenue [Table Text Block]",
        "terseLabel": "Disaggregation of revenue by product and by geographic area"
       }
      }
     },
     "localname": "DisaggregationOfRevenueTableTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/RevenuesTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_DividendsCommonStockCash": {
     "auth_ref": [
      "r338"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of paid and unpaid common stock dividends declared with the form of settlement in cash.",
        "label": "Dividends, Common Stock, Cash",
        "negatedTerseLabel": "Dividends declared on common stock"
       }
      }
     },
     "localname": "DividendsCommonStockCash",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_EarningsPerShareAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Earnings Per Share [Abstract]",
        "terseLabel": "Earnings Per Share [Abstract]",
        "verboseLabel": "Earnings per share:"
       }
      }
     },
     "localname": "EarningsPerShareAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_EarningsPerShareBasic": {
     "auth_ref": [
      "r74",
      "r122",
      "r123",
      "r124",
      "r125",
      "r126",
      "r131",
      "r133",
      "r137",
      "r138",
      "r139",
      "r143",
      "r144",
      "r457",
      "r458",
      "r539",
      "r560"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The amount of net income (loss) for the period per each share of common stock or unit outstanding during the reporting period.",
        "label": "Earnings Per Share, Basic",
        "terseLabel": "Basic EPS (in usd per share)",
        "verboseLabel": "Basic (in usd per share)"
       }
      }
     },
     "localname": "EarningsPerShareBasic",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/EarningspershareDetails"
     ],
     "xbrltype": "perShareItemType"
    },
    "us-gaap_EarningsPerShareDiluted": {
     "auth_ref": [
      "r74",
      "r122",
      "r123",
      "r124",
      "r125",
      "r126",
      "r133",
      "r137",
      "r138",
      "r139",
      "r143",
      "r144",
      "r457",
      "r458",
      "r539",
      "r560"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The amount of net income (loss) for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.",
        "label": "Earnings Per Share, Diluted",
        "terseLabel": "Diluted EPS (in usd per share)",
        "verboseLabel": "Diluted (in usd per share)"
       }
      }
     },
     "localname": "EarningsPerShareDiluted",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/EarningspershareDetails"
     ],
     "xbrltype": "perShareItemType"
    },
    "us-gaap_EarningsPerShareTextBlock": {
     "auth_ref": [
      "r140",
      "r141",
      "r142",
      "r145"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure for earnings per share.",
        "label": "Earnings Per Share [Text Block]",
        "verboseLabel": "Earnings per share"
       }
      }
     },
     "localname": "EarningsPerShareTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/Earningspershare"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_EffectiveIncomeTaxRateContinuingOperations": {
     "auth_ref": [
      "r382"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Percentage of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.",
        "label": "Effective Income Tax Rate Reconciliation, Percent",
        "terseLabel": "Effective income tax rate"
       }
      }
     },
     "localname": "EffectiveIncomeTaxRateContinuingOperations",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/IncometaxesDetails"
     ],
     "xbrltype": "percentItemType"
    },
    "us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Revenue from External Customer [Line Items]",
        "terseLabel": "Revenue from External Customer [Line Items]"
       }
      }
     },
     "localname": "EntityWideInformationRevenueFromExternalCustomerLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_EquityAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Equity [Abstract]",
        "terseLabel": "Equity [Abstract]"
       }
      }
     },
     "localname": "EquityAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_EquityComponentDomain": {
     "auth_ref": [
      "r0",
      "r66",
      "r67",
      "r68",
      "r116",
      "r117",
      "r118",
      "r121",
      "r127",
      "r129",
      "r146",
      "r211",
      "r331",
      "r338",
      "r372",
      "r373",
      "r374",
      "r387",
      "r388",
      "r456",
      "r472",
      "r473",
      "r474",
      "r475",
      "r476",
      "r478",
      "r569",
      "r570",
      "r571",
      "r624"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Components of equity are the parts of the total Equity balance including that which is allocated to common, preferred, treasury stock, retained earnings, etc.",
        "label": "Equity Component [Domain]",
        "terseLabel": "Equity Component [Domain]"
       }
      }
     },
     "localname": "EquityComponentDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_EquityMethodInvestmentAggregateCost": {
     "auth_ref": [
      "r30"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "This element represents the aggregate cost of investments accounted for under the equity method of accounting.",
        "label": "Equity Method Investment, Aggregate Cost",
        "terseLabel": "Equity Method Investment, Aggregate Cost"
       }
      }
     },
     "localname": "EquityMethodInvestmentAggregateCost",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity": {
     "auth_ref": [
      "r208"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Difference between amount at which an investment accounted for under the equity method of accounting is carried (reported) on the balance sheet and amount of underlying equity in net assets the reporting Entity has in the investee.",
        "label": "Equity Method Investment, Difference Between Carrying Amount and Underlying Equity",
        "terseLabel": "Equity Method Investment, Difference Between Carrying Amount and Underlying Equity"
       }
      }
     },
     "localname": "EquityMethodInvestmentDifferenceBetweenCarryingAmountAndUnderlyingEquity",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_EquityMethodInvestmentOwnershipPercentage": {
     "auth_ref": [
      "r207"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The percentage of ownership of common stock or equity participation in the investee accounted for under the equity method of accounting.",
        "label": "Equity Method Investment, Ownership Percentage",
        "terseLabel": "Ownership percentage"
       }
      }
     },
     "localname": "EquityMethodInvestmentOwnershipPercentage",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "percentItemType"
    },
    "us-gaap_EquityMethodInvestmentQuotedMarketValue": {
     "auth_ref": [
      "r209"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "This item represents the aggregate value of each identified investment accounted for under the equity method of accounting based on the quoted market price for those investments in common stock for which a quoted market price is available.",
        "label": "Equity Method Investment, Quoted Market Value",
        "terseLabel": "Equity Method Investments,Quoted Market Price"
       }
      }
     },
     "localname": "EquityMethodInvestmentQuotedMarketValue",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_EquityMethodInvestments": {
     "auth_ref": [
      "r30",
      "r164",
      "r206"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "This item represents the carrying amount on the entity's balance sheet of its investment in common stock of an equity method investee. This is not an indicator of the fair value of the investment, rather it is the initial cost adjusted for the entity's share of earnings and losses of the investee, adjusted for any distributions (dividends) and other than temporary impairment (OTTI) losses recognized.",
        "label": "Equity Method Investments",
        "terseLabel": "Carrying value of equity method investment"
       }
      }
     },
     "localname": "EquityMethodInvestments",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_EquityMethodInvestmentsFairValueDisclosure": {
     "auth_ref": [
      "r205"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value portion of investments accounted under the equity method.",
        "label": "Equity Method Investments, Fair Value Disclosure",
        "terseLabel": "Equity Method Investments, Fair Value Disclosure"
       }
      }
     },
     "localname": "EquityMethodInvestmentsFairValueDisclosure",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_EquitySecuritiesFvNi": {
     "auth_ref": [
      "r469"
     ],
     "calculation": {
      "http://www.amgen.com/role/FairvaluemeasurementDetails": {
       "order": 2.0,
       "parentTag": "us-gaap_AssetsFairValueDisclosure",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of investment in equity security measured at fair value with change in fair value recognized in net income (FV-NI), classified as current.",
        "label": "Equity Securities, FV-NI, Current",
        "terseLabel": "Equity securities"
       }
      }
     },
     "localname": "EquitySecuritiesFvNi",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_EquitySecuritiesFvNiUnrealizedGainLoss": {
     "auth_ref": [
      "r204",
      "r561"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of unrealized gain (loss) on investment in equity security measured at fair value with change in fair value recognized in net income (FV-NI).",
        "label": "Equity Securities, FV-NI, Unrealized Gain (Loss)",
        "terseLabel": "Equity Securities, FV-NI, Unrealized Gain (Loss)"
       }
      }
     },
     "localname": "EquitySecuritiesFvNiUnrealizedGainLoss",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount": {
     "auth_ref": [
      "r201"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of investment in equity security without readily determinable fair value.",
        "label": "Equity Securities without Readily Determinable Fair Value, Amount",
        "terseLabel": "Equity securities without readily determinable fair value"
       }
      }
     },
     "localname": "EquitySecuritiesWithoutReadilyDeterminableFairValueAmount",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount": {
     "auth_ref": [
      "r203"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of gain from upward price adjustment on investment in equity security without readily determinable fair value.",
        "label": "Equity Securities without Readily Determinable Fair Value, Upward Price Adjustment, Annual Amount",
        "terseLabel": "Equity Securities without Readily Determinable Fair Value, Upward Price Adjustment, Annual Amount"
       }
      }
     },
     "localname": "EquitySecuritiesWithoutReadilyDeterminableFairValueUpwardPriceAdjustmentAnnualAmount",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]",
        "terseLabel": "Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]"
       }
      }
     },
     "localname": "FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable": {
     "auth_ref": [
      "r461",
      "r462",
      "r463",
      "r466"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Disclosure of information about asset and liability measured at fair value on recurring and nonrecurring basis.",
        "label": "Fair Value, Recurring and Nonrecurring [Table]",
        "terseLabel": "Fair Value, Recurring and Nonrecurring [Table]"
       }
      }
     },
     "localname": "FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_FairValueByFairValueHierarchyLevelAxis": {
     "auth_ref": [
      "r289",
      "r307",
      "r308",
      "r355",
      "r356",
      "r357",
      "r358",
      "r359",
      "r360",
      "r361",
      "r362",
      "r462",
      "r495",
      "r496",
      "r497"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by level within fair value hierarchy and fair value measured at net asset value per share as practical expedient.",
        "label": "Fair Value Hierarchy and NAV [Axis]",
        "terseLabel": "Fair Value Hierarchy and NAV [Axis]"
       }
      }
     },
     "localname": "FairValueByFairValueHierarchyLevelAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_FairValueByLiabilityClassAxis": {
     "auth_ref": [
      "r465",
      "r466"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by class of liability.",
        "label": "Liability Class [Axis]",
        "terseLabel": "Liability Class [Axis]"
       }
      }
     },
     "localname": "FairValueByLiabilityClassAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_FairValueDisclosuresAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Fair Value Disclosures [Abstract]",
        "terseLabel": "Fair Value Disclosures [Abstract]"
       }
      }
     },
     "localname": "FairValueDisclosuresAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_FairValueDisclosuresTextBlock": {
     "auth_ref": [
      "r465"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure for the fair value of financial instruments (as defined), including financial assets and financial liabilities (collectively, as defined), and the measurements of those instruments as well as disclosures related to the fair value of non-financial assets and liabilities. Such disclosures about the financial instruments, assets, and liabilities would include: (1) the fair value of the required items together with their carrying amounts (as appropriate); (2) for items for which it is not practicable to estimate fair value, disclosure would include: (a) information pertinent to estimating fair value (including, carrying amount, effective interest rate, and maturity, and (b) the reasons why it is not practicable to estimate fair value; (3) significant concentrations of credit risk including: (a) information about the activity, region, or economic characteristics identifying a concentration, (b) the maximum amount of loss the entity is exposed to based on the gross fair value of the related item, (c) policy for requiring collateral or other security and information as to accessing such collateral or security, and (d) the nature and brief description of such collateral or security; (4) quantitative information about market risks and how such risks are managed; (5) for items measured on both a recurring and nonrecurring basis information regarding the inputs used to develop the fair value measurement; and (6) for items presented in the financial statement for which fair value measurement is elected: (a) information necessary to understand the reasons for the election, (b) discussion of the effect of fair value changes on earnings, (c) a description of [similar groups] items for which the election is made and the relation thereof to the balance sheet, the aggregate carrying value of items included in the balance sheet that are not eligible for the election; (7) all other required (as defined) and desired information.",
        "label": "Fair Value Disclosures [Text Block]",
        "verboseLabel": "Fair value measurement"
       }
      }
     },
     "localname": "FairValueDisclosuresTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/Fairvaluemeasurement"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_FairValueInputsLevel1Member": {
     "auth_ref": [
      "r289",
      "r355",
      "r356",
      "r361",
      "r362",
      "r462",
      "r495"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Quoted prices in active markets for identical assets or liabilities that the reporting entity can access at the measurement date.",
        "label": "Fair Value, Inputs, Level 1 [Member]",
        "terseLabel": "Fair Value, Inputs, Level 1 [Member]",
        "verboseLabel": "Quoted prices in active markets for identical assets (Level 1) [Member]"
       }
      }
     },
     "localname": "FairValueInputsLevel1Member",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_FairValueInputsLevel2Member": {
     "auth_ref": [
      "r289",
      "r307",
      "r308",
      "r355",
      "r356",
      "r361",
      "r362",
      "r462",
      "r496"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Inputs other than quoted prices included within level 1 that are observable for an asset or liability, either directly or indirectly, including, but not limited to, quoted prices for similar assets or liabilities in active markets, or quoted prices for identical or similar assets or liabilities in inactive markets.",
        "label": "Fair Value, Inputs, Level 2 [Member]",
        "verboseLabel": "Significant other observable inputs (Level 2) [Member]"
       }
      }
     },
     "localname": "FairValueInputsLevel2Member",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_FairValueInputsLevel3Member": {
     "auth_ref": [
      "r289",
      "r307",
      "r308",
      "r355",
      "r356",
      "r357",
      "r358",
      "r359",
      "r360",
      "r361",
      "r362",
      "r462",
      "r497"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing.",
        "label": "Fair Value, Inputs, Level 3 [Member]",
        "verboseLabel": "Significant unobservable inputs (Level 3) [Member]"
       }
      }
     },
     "localname": "FairValueInputsLevel3Member",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain": {
     "auth_ref": [
      "r464"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Represents classes of liabilities measured and disclosed at fair value.",
        "label": "Fair Value by Liability Class [Domain]",
        "terseLabel": "Fair Value by Liability Class [Domain]"
       }
      }
     },
     "localname": "FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember": {
     "auth_ref": [
      "r356",
      "r460",
      "r468"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value measured at net asset value per share as practical expedient.",
        "label": "Fair Value Measured at Net Asset Value Per Share [Member]",
        "terseLabel": "Fair Value Measured at Net Asset Value Per Share [Member]"
       }
      }
     },
     "localname": "FairValueMeasuredAtNetAssetValuePerShareMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_FairValueMeasurementsFairValueHierarchyDomain": {
     "auth_ref": [
      "r289",
      "r307",
      "r308",
      "r355",
      "r356",
      "r357",
      "r358",
      "r359",
      "r360",
      "r361",
      "r362",
      "r495",
      "r496",
      "r497"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Categories used to prioritize the inputs to valuation techniques to measure fair value.",
        "label": "Fair Value Hierarchy and NAV [Domain]",
        "terseLabel": "Fair Value Hierarchy and NAV [Domain]"
       }
      }
     },
     "localname": "FairValueMeasurementsFairValueHierarchyDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable": {
     "auth_ref": [
      "r428",
      "r434",
      "r448"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Schedule that discloses the location and fair value amounts of derivative instruments (and nonderivative instruments that are designated and qualify as hedging instruments) reported in the statement of financial position.",
        "label": "Fair Values Derivatives, Balance Sheet Location, by Derivative Contract Type [Table]",
        "terseLabel": "Fair Values Derivatives Balance Sheet Location By Derivative Contract Type By Hedging Designation [Table]"
       }
      }
     },
     "localname": "FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_FinancialInstrumentAxis": {
     "auth_ref": [
      "r193",
      "r194",
      "r201",
      "r202",
      "r203",
      "r212",
      "r213",
      "r214",
      "r215",
      "r216",
      "r218",
      "r219",
      "r220",
      "r221",
      "r300",
      "r329",
      "r453",
      "r492",
      "r493",
      "r494",
      "r495",
      "r496",
      "r497",
      "r498",
      "r499",
      "r500",
      "r501",
      "r502",
      "r503",
      "r504",
      "r506",
      "r507",
      "r508",
      "r509",
      "r510",
      "r511",
      "r512",
      "r513",
      "r514",
      "r515",
      "r516",
      "r517",
      "r518",
      "r519",
      "r520",
      "r521",
      "r522",
      "r614",
      "r615",
      "r616",
      "r617",
      "r618",
      "r619",
      "r620"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by type of financial instrument.",
        "label": "Financial Instrument [Axis]",
        "terseLabel": "Financial Instrument [Axis]"
       }
      }
     },
     "localname": "FinancialInstrumentAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsDetails",
      "http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_FiniteLivedIntangibleAssetUsefulLife": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Useful life of finite-lived intangible assets, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.",
        "label": "Finite-Lived Intangible Asset, Useful Life",
        "terseLabel": "Finite-Lived Intangible Asset, Useful Life"
       }
      }
     },
     "localname": "FiniteLivedIntangibleAssetUsefulLife",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "durationItemType"
    },
    "us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization": {
     "auth_ref": [
      "r237"
     ],
     "calculation": {
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails": {
       "order": 2.0,
       "parentTag": "us-gaap_FiniteLivedIntangibleAssetsNet",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Accumulated amount of amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.",
        "label": "Finite-Lived Intangible Assets, Accumulated Amortization",
        "negatedTerseLabel": "Accumulated amortization"
       }
      }
     },
     "localname": "FiniteLivedIntangibleAssetsAccumulatedAmortization",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths": {
     "auth_ref": [
      "r239"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of amortization for assets, excluding financial assets and goodwill, lacking physical substance with finite life expected to be recognized in next fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).",
        "label": "Finite-Lived Intangible Asset, Expected Amortization, Year One",
        "terseLabel": "Total estimated amortization of finite-lived intangible assets for 2022"
       }
      }
     },
     "localname": "FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear": {
     "auth_ref": [],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of amortization for assets, excluding financial assets and goodwill, lacking physical substance with finite life expected to be recognized in remainder of current fiscal year.",
        "label": "Finite-Lived Intangible Asset, Expected Amortization, Remainder of Fiscal Year",
        "terseLabel": "Total estimated amortization of finite-lived intangible assets for the six months ending December 31, 2021"
       }
      }
     },
     "localname": "FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive": {
     "auth_ref": [
      "r239"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of amortization for assets, excluding financial assets and goodwill, lacking physical substance with finite life expected to be recognized in fifth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).",
        "label": "Finite-Lived Intangible Asset, Expected Amortization, Year Five",
        "terseLabel": "Total estimated amortization of finite-lived intangible assets for 2026"
       }
      }
     },
     "localname": "FiniteLivedIntangibleAssetsAmortizationExpenseYearFive",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour": {
     "auth_ref": [
      "r239"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of amortization for assets, excluding financial assets and goodwill, lacking physical substance with finite life expected to be recognized in fourth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).",
        "label": "Finite-Lived Intangible Asset, Expected Amortization, Year Four",
        "terseLabel": "Total estimated amortization of finite-lived intangible assets for 2025"
       }
      }
     },
     "localname": "FiniteLivedIntangibleAssetsAmortizationExpenseYearFour",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree": {
     "auth_ref": [
      "r239"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of amortization for assets, excluding financial assets and goodwill, lacking physical substance with finite life expected to be recognized in third fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).",
        "label": "Finite-Lived Intangible Asset, Expected Amortization, Year Three",
        "terseLabel": "Total estimated amortization of finite-lived intangible assets for 2024"
       }
      }
     },
     "localname": "FiniteLivedIntangibleAssetsAmortizationExpenseYearThree",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo": {
     "auth_ref": [
      "r239"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of amortization for assets, excluding financial assets and goodwill, lacking physical substance with finite life expected to be recognized in second fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).",
        "label": "Finite-Lived Intangible Asset, Expected Amortization, Year Two",
        "terseLabel": "Total estimated amortization of finite-lived intangible assets for 2023"
       }
      }
     },
     "localname": "FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis": {
     "auth_ref": [
      "r231",
      "r234",
      "r237",
      "r241",
      "r525",
      "r526"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by major type or class of finite-lived intangible assets.",
        "label": "Finite-Lived Intangible Assets by Major Class [Axis]",
        "terseLabel": "Finite-Lived Intangible Assets by Major Class [Axis]"
       }
      }
     },
     "localname": "FiniteLivedIntangibleAssetsByMajorClassAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_FiniteLivedIntangibleAssetsGross": {
     "auth_ref": [
      "r237",
      "r526"
     ],
     "calculation": {
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails": {
       "order": 1.0,
       "parentTag": "us-gaap_FiniteLivedIntangibleAssetsNet",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount before amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.",
        "label": "Finite-Lived Intangible Assets, Gross",
        "terseLabel": "Gross carrying amounts"
       }
      }
     },
     "localname": "FiniteLivedIntangibleAssetsGross",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_FiniteLivedIntangibleAssetsLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Finite-Lived Intangible Assets [Line Items]",
        "terseLabel": "Finite-Lived Intangible Assets [Line Items]"
       }
      }
     },
     "localname": "FiniteLivedIntangibleAssetsLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain": {
     "auth_ref": [
      "r231",
      "r236"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The major class of finite-lived intangible asset (for example, patents, trademarks, copyrights, etc.) A major class is composed of intangible assets that can be grouped together because they are similar, either by their nature or by their use in the operations of a company.",
        "label": "Finite-Lived Intangible Assets, Major Class Name [Domain]",
        "terseLabel": "Finite-Lived Intangible Assets, Major Class Name [Domain]"
       }
      }
     },
     "localname": "FiniteLivedIntangibleAssetsMajorClassNameDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_FiniteLivedIntangibleAssetsNet": {
     "auth_ref": [
      "r237",
      "r525"
     ],
     "calculation": {
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount after amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.",
        "label": "Finite-Lived Intangible Assets, Net",
        "totalLabel": "Other intangible assets, net"
       }
      }
     },
     "localname": "FiniteLivedIntangibleAssetsNet",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months": {
     "auth_ref": [
      "r451"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The estimated net amount of unrealized gains or losses on foreign currency cash flow hedges at the reporting date expected to be reclassified to earnings within the next 12 months.",
        "label": "Foreign Currency Cash Flow Hedge Gain (Loss) to be Reclassified During Next 12 Months",
        "terseLabel": "Amounts expected to be reclassified from AOCI into earnings over the next 12 months, foreign currency and cross-currency swaps"
       }
      }
     },
     "localname": "ForeignCurrencyCashFlowHedgeGainLossToBeReclassifiedDuringNext12Months",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ForeignCurrencyContractAssetFairValueDisclosure": {
     "auth_ref": [],
     "calculation": {
      "http://www.amgen.com/role/FairvaluemeasurementDetails": {
       "order": 3.0,
       "parentTag": "us-gaap_AssetsFairValueDisclosure",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value portion of asset contracts related to the exchange of different currencies, including, but not limited to, foreign currency options, forward contracts, and swaps.",
        "label": "Foreign Currency Contract, Asset, Fair Value Disclosure",
        "verboseLabel": "Foreign currency and cross-currency swap contracts"
       }
      }
     },
     "localname": "ForeignCurrencyContractAssetFairValueDisclosure",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure": {
     "auth_ref": [],
     "calculation": {
      "http://www.amgen.com/role/FairvaluemeasurementDetails": {
       "order": 1.0,
       "parentTag": "us-gaap_LiabilitiesFairValueDisclosure",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value portion of liability contracts related to the exchange of different currencies, including, but not limited to, foreign currency options, forward (delivery or nondelivery) contracts, and swaps entered into.",
        "label": "Foreign Currency Contracts, Liability, Fair Value Disclosure",
        "verboseLabel": "Foreign currency and cross-currency swap contracts"
       }
      }
     },
     "localname": "ForeignCurrencyContractsLiabilityFairValueDisclosure",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ForeignExchangeContractMember": {
     "auth_ref": [
      "r49",
      "r355",
      "r440"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Derivative instrument whose primary underlying risk is tied to foreign exchange rates.",
        "label": "Foreign Exchange Contract [Member]",
        "terseLabel": "Foreign currency contract [Member]",
        "verboseLabel": "Foreign currency contracts [Member]"
       }
      }
     },
     "localname": "ForeignExchangeContractMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_ForeignGovernmentDebtSecuritiesMember": {
     "auth_ref": [
      "r355",
      "r575"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Debt security issued by government not domiciled in United States of America (US).",
        "label": "Debt Security, Government, Non-US [Member]",
        "terseLabel": "Other government-related debt securities - Foreign and other [Member]"
       }
      }
     },
     "localname": "ForeignGovernmentDebtSecuritiesMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_ForwardContractsMember": {
     "auth_ref": [
      "r438"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Contracts negotiated between two parties to purchase and sell a specific quantity of a financial instrument, foreign currency, or commodity at a price specified at origination of the contract, with delivery and settlement at a specified future date.",
        "label": "Forward Contracts [Member]",
        "verboseLabel": "Foreign currency forward contracts [Member]"
       }
      }
     },
     "localname": "ForwardContractsMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_GainContingencyPatentsFoundInfringedUponNumber": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Number of entity's patents that another entity was found to have infringed.",
        "label": "Gain Contingency, Patents Found Infringed upon, Number",
        "terseLabel": "Gain Contingency, Patents Found Infringed upon, Number"
       }
      }
     },
     "localname": "GainContingencyPatentsFoundInfringedUponNumber",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "integerItemType"
    },
    "us-gaap_Goodwill": {
     "auth_ref": [
      "r224",
      "r225",
      "r487",
      "r528"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 4.0,
       "parentTag": "us-gaap_Assets",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount after accumulated impairment loss of an asset representing future economic benefits arising from other assets acquired in a business combination that are not individually identified and separately recognized.",
        "label": "Goodwill",
        "periodEndLabel": "Ending balance",
        "periodStartLabel": "Beginning balance",
        "terseLabel": "Goodwill"
       }
      }
     },
     "localname": "Goodwill",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets",
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsGoodwillRollForwardDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Goodwill and Intangible Assets Disclosure [Abstract]",
        "terseLabel": "Goodwill and Intangible Assets Disclosure [Abstract]"
       }
      }
     },
     "localname": "GoodwillAndIntangibleAssetsDisclosureAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock": {
     "auth_ref": [
      "r243"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure for goodwill and intangible assets.",
        "label": "Goodwill and Intangible Assets Disclosure [Text Block]",
        "terseLabel": "Goodwill and other intangible assets"
       }
      }
     },
     "localname": "GoodwillAndIntangibleAssetsDisclosureTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/Goodwillandotherintangibleassets"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_GoodwillForeignCurrencyTranslationGainLoss": {
     "auth_ref": [
      "r226"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of foreign currency translation gain (loss) which increases (decreases) an asset representing future economic benefits from other assets acquired in a business combination that are not individually identified and separately recognized.",
        "label": "Goodwill, Foreign Currency Translation Gain (Loss)",
        "terseLabel": "Currency translation adjustment"
       }
      }
     },
     "localname": "GoodwillForeignCurrencyTranslationGainLoss",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsGoodwillRollForwardDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_GoodwillRollForward": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period.",
        "label": "Goodwill [Roll Forward]",
        "terseLabel": "Goodwill [Roll Forward]"
       }
      }
     },
     "localname": "GoodwillRollForward",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsGoodwillRollForwardDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease": {
     "auth_ref": [
      "r445"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of cumulative increase (decrease) in fair value of hedged liability in fair value hedge, attributable to hedged risk, remaining after discontinued hedge.",
        "label": "Hedged Liability, Discontinued Fair Value Hedge, Cumulative Increase (Decrease)",
        "terseLabel": "Hedging adjustments on discontinued hedging relationships"
       }
      }
     },
     "localname": "HedgedLiabilityDiscontinuedFairValueHedgeCumulativeIncreaseDecrease",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_HedgedLiabilityFairValueHedge": {
     "auth_ref": [
      "r443"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of liability hedged in fair value hedging relationship.",
        "label": "Hedged Liability, Fair Value Hedge",
        "terseLabel": "Hedged Liability, Fair Value Hedge"
       }
      }
     },
     "localname": "HedgedLiabilityFairValueHedge",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease": {
     "auth_ref": [
      "r444"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of cumulative increase (decrease) in fair value of hedged liability in fair value hedge, attributable to hedged risk.",
        "label": "Hedged Liability, Fair Value Hedge, Cumulative Increase (Decrease)",
        "terseLabel": "Cumulative amounts of fair value hedging adjustments related to the carrying amounts of the hedged liabilities",
        "verboseLabel": "Fair value adjustments"
       }
      }
     },
     "localname": "HedgedLiabilityFairValueHedgeCumulativeIncreaseDecrease",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_HedgingDesignationAxis": {
     "auth_ref": [
      "r426",
      "r442"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by designation of purpose of derivative instrument.",
        "label": "Hedging Designation [Axis]",
        "terseLabel": "Hedging Designation [Axis]"
       }
      }
     },
     "localname": "HedgingDesignationAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_HedgingDesignationDomain": {
     "auth_ref": [
      "r426"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Designation of purpose of derivative instrument.",
        "label": "Hedging Designation [Domain]",
        "terseLabel": "Hedging Designation [Domain]"
       }
      }
     },
     "localname": "HedgingDesignationDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_HedgingRelationshipDomain": {
     "auth_ref": [
      "r426"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Nature or intent of a hedge.",
        "label": "Hedging Relationship [Domain]",
        "terseLabel": "Hedging Relationship [Domain]"
       }
      }
     },
     "localname": "HedgingRelationshipDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsCrosscurrencySwapsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_InProcessResearchAndDevelopmentMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "In process investigation of new knowledge useful in developing new product or service or new process or technique or improvement to existing product or process, and translation of knowledge into plan or design for new product or process or for improvement to existing product or process.",
        "label": "In Process Research and Development [Member]",
        "terseLabel": "In-process Research and Development [Member]"
       }
      }
     },
     "localname": "InProcessResearchAndDevelopmentMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments": {
     "auth_ref": [
      "r163",
      "r166",
      "r168",
      "r171",
      "r173"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome": {
       "order": 1.0,
       "parentTag": "us-gaap_NetIncomeLoss",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of income (loss) from continuing operations before deduction of income tax expense (benefit) and income (loss) attributable to noncontrolling interest, and addition of income (loss) from equity method investments.",
        "label": "Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Noncontrolling Interest",
        "terseLabel": "Income before income taxes",
        "totalLabel": "Income before income taxes"
       }
      }
     },
     "localname": "IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_IncomeLossFromEquityMethodInvestments": {
     "auth_ref": [
      "r70",
      "r97",
      "r161",
      "r206",
      "r535",
      "r556"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of income (loss) for proportionate share of equity method investee's income (loss).",
        "label": "Income (Loss) from Equity Method Investments",
        "terseLabel": "Income (Loss) from Equity Method Investments"
       }
      }
     },
     "localname": "IncomeLossFromEquityMethodInvestments",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_IncomeStatementAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Income Statement [Abstract]",
        "terseLabel": "Income Statement [Abstract]"
       }
      }
     },
     "localname": "IncomeStatementAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_IncomeStatementLocationAxis": {
     "auth_ref": [
      "r246",
      "r247"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by location in the income statement.",
        "label": "Income Statement Location [Axis]",
        "terseLabel": "Income Statement Location [Axis]"
       }
      }
     },
     "localname": "IncomeStatementLocationAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_IncomeStatementLocationDomain": {
     "auth_ref": [
      "r247"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Location in the income statement.",
        "label": "Income Statement Location [Domain]",
        "terseLabel": "Income Statement Location [Domain]"
       }
      }
     },
     "localname": "IncomeStatementLocationDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_IncomeTaxDisclosureAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Income Tax Disclosure [Abstract]",
        "terseLabel": "Income Tax Disclosure [Abstract]"
       }
      }
     },
     "localname": "IncomeTaxDisclosureAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_IncomeTaxDisclosureTextBlock": {
     "auth_ref": [
      "r111",
      "r383",
      "r385",
      "r386",
      "r389",
      "r391",
      "r393",
      "r394",
      "r395"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure for income taxes. Disclosures may include net deferred tax liability or asset recognized in an enterprise's statement of financial position, net change during the year in the total valuation allowance, approximate tax effect of each type of temporary difference and carryforward that gives rise to a significant portion of deferred tax liabilities and deferred tax assets, utilization of a tax carryback, and tax uncertainties information.",
        "label": "Income Tax Disclosure [Text Block]",
        "verboseLabel": "Income taxes"
       }
      }
     },
     "localname": "IncomeTaxDisclosureTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/Incometaxes"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_IncomeTaxExpenseBenefit": {
     "auth_ref": [
      "r112",
      "r128",
      "r129",
      "r162",
      "r381",
      "r390",
      "r392",
      "r562"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome": {
       "order": 2.0,
       "parentTag": "us-gaap_NetIncomeLoss",
       "weight": -1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.",
        "label": "Income Tax Expense (Benefit)",
        "negatedTerseLabel": "Provision for income taxes",
        "verboseLabel": "Provision for income taxes"
       }
      }
     },
     "localname": "IncomeTaxExpenseBenefit",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_IncreaseDecreaseInAccountsPayable": {
     "auth_ref": [
      "r96"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 9.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The increase (decrease) during the reporting period in the aggregate amount of liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business.",
        "label": "Increase (Decrease) in Accounts Payable",
        "verboseLabel": "Accounts payable"
       }
      }
     },
     "localname": "IncreaseDecreaseInAccountsPayable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_IncreaseDecreaseInAccountsReceivable": {
     "auth_ref": [
      "r96"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 6.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The increase (decrease) during the reporting period in amount due within one year (or one business cycle) from customers for the credit sale of goods and services.",
        "label": "Increase (Decrease) in Accounts Receivable",
        "negatedLabel": "Trade receivables, net"
       }
      }
     },
     "localname": "IncreaseDecreaseInAccountsReceivable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable": {
     "auth_ref": [
      "r96"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 10.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The increase (decrease) during the period in the amount due for taxes based on the reporting entity's earnings or attributable to the entity's income earning process (business presence) within a given jurisdiction.",
        "label": "Increase (Decrease) in Income Taxes Payable",
        "verboseLabel": "Accrued income taxes, net"
       }
      }
     },
     "localname": "IncreaseDecreaseInAccruedIncomeTaxesPayable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_IncreaseDecreaseInInventories": {
     "auth_ref": [
      "r96"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 7.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The increase (decrease) during the reporting period in the aggregate value of all inventory held by the reporting entity, associated with underlying transactions that are classified as operating activities.",
        "label": "Increase (Decrease) in Inventories",
        "negatedLabel": "Inventories"
       }
      }
     },
     "localname": "IncreaseDecreaseInInventories",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_IncreaseDecreaseInOperatingCapitalAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Increase (Decrease) in Operating Capital [Abstract]",
        "verboseLabel": "Changes in operating assets and liabilities, net of acquisitions:"
       }
      }
     },
     "localname": "IncreaseDecreaseInOperatingCapitalAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_IncreaseDecreaseInOtherOperatingAssets": {
     "auth_ref": [
      "r96"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 8.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of increase (decrease) in operating assets classified as other.",
        "label": "Increase (Decrease) in Other Operating Assets",
        "negatedLabel": "Other assets"
       }
      }
     },
     "localname": "IncreaseDecreaseInOtherOperatingAssets",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_IncreaseDecreaseInOtherOperatingLiabilities": {
     "auth_ref": [
      "r96"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 12.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of increase (decrease) in operating liabilities classified as other.",
        "label": "Increase (Decrease) in Other Operating Liabilities",
        "verboseLabel": "Other liabilities"
       }
      }
     },
     "localname": "IncreaseDecreaseInOtherOperatingLiabilities",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_IncreaseDecreaseInStockholdersEquityRollForward": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period.",
        "label": "Increase (Decrease) in Stockholders' Equity [Roll Forward]",
        "terseLabel": "Increase (Decrease) in Stockholders' Equity [Roll Forward]",
        "verboseLabel": "Increase (Decrease) in AOCI [Roll Forward]"
       }
      }
     },
     "localname": "IncreaseDecreaseInStockholdersEquityRollForward",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity",
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis": {
     "auth_ref": [
      "r232",
      "r240"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by type or class of assets, excluding financial assets and goodwill, lacking physical substance and having a projected indefinite period of benefit.",
        "label": "Indefinite-lived Intangible Assets [Axis]",
        "terseLabel": "Indefinite-lived Intangible Assets [Axis]"
       }
      }
     },
     "localname": "IndefiniteLivedIntangibleAssetsByMajorClassAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Indefinite-lived Intangible Assets [Line Items]",
        "terseLabel": "Indefinite-lived Intangible Assets [Line Items]"
       }
      }
     },
     "localname": "IndefiniteLivedIntangibleAssetsByMajorClassLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill": {
     "auth_ref": [
      "r240"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of assets, excluding financial assets and goodwill, lacking physical substance and having a projected indefinite period of benefit.",
        "label": "Indefinite-lived Intangible Assets (Excluding Goodwill)",
        "terseLabel": "Indefinite-lived intangible assets"
       }
      }
     },
     "localname": "IndefiniteLivedIntangibleAssetsExcludingGoodwill",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain": {
     "auth_ref": [
      "r232",
      "r240"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The major class of indefinite-lived intangible asset (for example, trade names, etc. but not all-inclusive), excluding goodwill. A major class is composed of intangible assets that can be grouped together because they are similar, either by their nature or by their use in the operations of the company.",
        "label": "Indefinite-lived Intangible Assets, Major Class Name [Domain]",
        "terseLabel": "Indefinite-lived Intangible Assets, Major Class Name [Domain]"
       }
      }
     },
     "localname": "IndefiniteLivedIntangibleAssetsMajorClassNameDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_IntangibleAssetsNetExcludingGoodwill": {
     "auth_ref": [
      "r229",
      "r235"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 3.0,
       "parentTag": "us-gaap_Assets",
       "weight": 1.0
      },
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Sum of the carrying amounts of all intangible assets, excluding goodwill, as of the balance sheet date, net of accumulated amortization and impairment charges.",
        "label": "Intangible Assets, Net (Excluding Goodwill)",
        "totalLabel": "Intangible assets, net",
        "verboseLabel": "Intangible assets, net"
       }
      }
     },
     "localname": "IntangibleAssetsNetExcludingGoodwill",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets",
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_InterestExpenseDebt": {
     "auth_ref": [
      "r82",
      "r295",
      "r306",
      "r309",
      "r310"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome": {
       "order": 2.0,
       "parentTag": "us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments",
       "weight": -1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of the cost of borrowed funds accounted for as interest expense for debt.",
        "label": "Interest Expense, Debt",
        "negatedTerseLabel": "Interest expense, net"
       }
      }
     },
     "localname": "InterestExpenseDebt",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_InterestRateFairValueHedgeAssetAtFairValue": {
     "auth_ref": [
      "r432"
     ],
     "calculation": {
      "http://www.amgen.com/role/FairvaluemeasurementDetails": {
       "order": 4.0,
       "parentTag": "us-gaap_AssetsFairValueDisclosure",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value as of the balance sheet date of all derivative assets designated as interest rate fair value hedging instruments.",
        "label": "Interest Rate Fair Value Hedge Asset at Fair Value",
        "terseLabel": "Interest rate swap contracts"
       }
      }
     },
     "localname": "InterestRateFairValueHedgeAssetAtFairValue",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue": {
     "auth_ref": [
      "r432"
     ],
     "calculation": {
      "http://www.amgen.com/role/FairvaluemeasurementDetails": {
       "order": 2.0,
       "parentTag": "us-gaap_LiabilitiesFairValueDisclosure",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value as of the balance sheet date of all derivative liabilities designated as interest rate fair value hedging instruments.",
        "label": "Interest Rate Fair Value Hedge Liability at Fair Value",
        "terseLabel": "Interest rate swap contracts"
       }
      }
     },
     "localname": "InterestRateFairValueHedgeLiabilityAtFairValue",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_InterestRateSwapMember": {
     "auth_ref": [
      "r439"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Forward based contracts in which two parties agree to swap periodic payments that are fixed at the outset of the swap contract with variable payments based on a market interest rate (index rate) over a specified period.",
        "label": "Interest Rate Swap [Member]",
        "netLabel": "Interest rate swap agreements [Member]",
        "terseLabel": "Interest Rate Swap [Member]",
        "verboseLabel": "Interest rate swap contracts [Member]"
       }
      }
     },
     "localname": "InterestRateSwapMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_InventoryDisclosureAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Inventory Disclosure [Abstract]",
        "terseLabel": "Inventory Disclosure [Abstract]"
       }
      }
     },
     "localname": "InventoryDisclosureAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_InventoryDisclosureTextBlock": {
     "auth_ref": [
      "r223"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure for inventory. Includes, but is not limited to, the basis of stating inventory, the method of determining inventory cost, the classes of inventory, and the nature of the cost elements included in inventory.",
        "label": "Inventory Disclosure [Text Block]",
        "verboseLabel": "Inventories"
       }
      }
     },
     "localname": "InventoryDisclosureTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/Inventories"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_InventoryFinishedGoodsNetOfReserves": {
     "auth_ref": [
      "r23",
      "r222"
     ],
     "calculation": {
      "http://www.amgen.com/role/InventoriesDetails": {
       "order": 3.0,
       "parentTag": "us-gaap_InventoryNet",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Carrying amount, net of valuation reserves and adjustments, as of the balance sheet date of merchandise or goods held by the company that are readily available for sale.",
        "label": "Inventory, Finished Goods, Net of Reserves",
        "verboseLabel": "Finished goods"
       }
      }
     },
     "localname": "InventoryFinishedGoodsNetOfReserves",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InventoriesDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_InventoryNet": {
     "auth_ref": [
      "r3",
      "r45",
      "r487"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 4.0,
       "parentTag": "us-gaap_AssetsCurrent",
       "weight": 1.0
      },
      "http://www.amgen.com/role/InventoriesDetails": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount after valuation and LIFO reserves of inventory expected to be sold, or consumed within one year or operating cycle, if longer.",
        "label": "Inventory, Net",
        "totalLabel": "Total inventories",
        "verboseLabel": "Inventories"
       }
      }
     },
     "localname": "InventoryNet",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets",
      "http://www.amgen.com/role/InventoriesDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_InventoryRawMaterialsNetOfReserves": {
     "auth_ref": [
      "r25",
      "r222"
     ],
     "calculation": {
      "http://www.amgen.com/role/InventoriesDetails": {
       "order": 1.0,
       "parentTag": "us-gaap_InventoryNet",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Carrying amount, net of valuation reserves and adjustments, as of the balance sheet date of unprocessed items to be consumed in the manufacturing or production process.",
        "label": "Inventory, Raw Materials, Net of Reserves",
        "verboseLabel": "Raw materials"
       }
      }
     },
     "localname": "InventoryRawMaterialsNetOfReserves",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InventoriesDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_InventoryWorkInProcessNetOfReserves": {
     "auth_ref": [
      "r24",
      "r222"
     ],
     "calculation": {
      "http://www.amgen.com/role/InventoriesDetails": {
       "order": 2.0,
       "parentTag": "us-gaap_InventoryNet",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Carrying amount, net of reserves and adjustments, as of the balance sheet date of merchandise or goods which are partially completed. This inventory is generally comprised of raw materials, labor and factory overhead costs, which require further materials, labor and overhead to be converted into finished goods, and which generally require the use of estimates to determine percentage complete and pricing.",
        "label": "Inventory, Work in Process, Net of Reserves",
        "verboseLabel": "Work in process"
       }
      }
     },
     "localname": "InventoryWorkInProcessNetOfReserves",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InventoriesDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_InvestmentTypeAxis": {
     "auth_ref": [
      "r578",
      "r579",
      "r580",
      "r581",
      "r582",
      "r583",
      "r584",
      "r585",
      "r586",
      "r587",
      "r588",
      "r589",
      "r590",
      "r591",
      "r592"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by type of investments.",
        "label": "Investment Type [Axis]",
        "terseLabel": "Investment Type [Axis]"
       }
      }
     },
     "localname": "InvestmentTypeAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_InvestmentTypeCategorizationMember": {
     "auth_ref": [
      "r578",
      "r579",
      "r580",
      "r581",
      "r582",
      "r583",
      "r584",
      "r585",
      "r586",
      "r587",
      "r588",
      "r589",
      "r590",
      "r591",
      "r592"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Asset obtained to generate income or appreciate in value.",
        "label": "Investments [Domain]",
        "terseLabel": "Investments [Domain]"
       }
      }
     },
     "localname": "InvestmentTypeCategorizationMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of maturities of an entity's investments as well as any other information pertinent to the investments.",
        "label": "Investments Classified by Contractual Maturity Date [Table Text Block]",
        "verboseLabel": "Fair values of available-for-sale interest-bearing security investments by contractual maturity"
       }
      }
     },
     "localname": "InvestmentsClassifiedByContractualMaturityDateTableTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Investments, Debt and Equity Securities [Abstract]",
        "terseLabel": "Investments, Debt and Equity Securities [Abstract]"
       }
      }
     },
     "localname": "InvestmentsDebtAndEquitySecuritiesAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock": {
     "auth_ref": [
      "r200",
      "r527",
      "r545",
      "r593",
      "r621"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure for  investments in certain debt and equity securities.",
        "label": "Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]",
        "verboseLabel": "Investments"
       }
      }
     },
     "localname": "InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/Investments"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_LiabilitiesAndStockholdersEquity": {
     "auth_ref": [
      "r22",
      "r110",
      "r210",
      "r470",
      "r487",
      "r532",
      "r553"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of liabilities and equity items, including the portion of equity attributable to noncontrolling interests, if any.",
        "label": "Liabilities and Equity",
        "totalLabel": "Total liabilities and stockholders\u2019 equity"
       }
      }
     },
     "localname": "LiabilitiesAndStockholdersEquity",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_LiabilitiesAndStockholdersEquityAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Liabilities and Equity [Abstract]",
        "verboseLabel": "LIABILITIES AND STOCKHOLDERS\u2019 EQUITY"
       }
      }
     },
     "localname": "LiabilitiesAndStockholdersEquityAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_LiabilitiesCurrent": {
     "auth_ref": [
      "r38",
      "r110",
      "r210",
      "r263",
      "r264",
      "r265",
      "r267",
      "r268",
      "r269",
      "r270",
      "r271",
      "r272",
      "r273",
      "r415",
      "r419",
      "r420",
      "r470",
      "r485",
      "r486",
      "r487"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 1.0,
       "parentTag": "us-gaap_LiabilitiesAndStockholdersEquity",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Total obligations incurred as part of normal operations that are expected to be paid during the following twelve months or within one business cycle, if longer.",
        "label": "Liabilities, Current",
        "totalLabel": "Total current liabilities"
       }
      }
     },
     "localname": "LiabilitiesCurrent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_LiabilitiesCurrentAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Liabilities, Current [Abstract]",
        "verboseLabel": "Current liabilities:"
       }
      }
     },
     "localname": "LiabilitiesCurrentAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_LiabilitiesFairValueDisclosure": {
     "auth_ref": [
      "r461"
     ],
     "calculation": {
      "http://www.amgen.com/role/FairvaluemeasurementDetails": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value of financial and nonfinancial obligations.",
        "label": "Financial and Nonfinancial Liabilities, Fair Value Disclosure",
        "totalLabel": "Total liabilities"
       }
      }
     },
     "localname": "LiabilitiesFairValueDisclosure",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_LiabilitiesFairValueDisclosureAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Liabilities, Fair Value Disclosure [Abstract]",
        "verboseLabel": "Liabilities:"
       }
      }
     },
     "localname": "LiabilitiesFairValueDisclosureAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_LiabilityForUncertainTaxPositionsNoncurrent": {
     "auth_ref": [
      "r41"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 3.0,
       "parentTag": "us-gaap_LiabilitiesAndStockholdersEquity",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount recognized for uncertainty in income taxes classified as noncurrent.",
        "label": "Liability for Uncertainty in Income Taxes, Noncurrent",
        "terseLabel": "Long-term tax liabilities"
       }
      }
     },
     "localname": "LiabilityForUncertainTaxPositionsNoncurrent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_LicensingAgreementsMember": {
     "auth_ref": [
      "r400"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Rights, generally of limited duration, under a license arrangement (for example, to sell or otherwise utilize specified products or processes in a specified territory).",
        "label": "Licensing Agreements [Member]",
        "terseLabel": "Licensing Rights [Member]"
       }
      }
     },
     "localname": "LicensingAgreementsMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_LitigationSettlementAmountAwardedFromOtherParty": {
     "auth_ref": [],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount awarded from other party in judgment or settlement of litigation.",
        "label": "Litigation Settlement, Amount Awarded from Other Party",
        "terseLabel": "Amount received from settlement"
       }
      }
     },
     "localname": "LitigationSettlementAmountAwardedFromOtherParty",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_LitigationSettlementExpense": {
     "auth_ref": [],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of litigation expense, including but not limited to legal, forensic, accounting, and investigative fees.",
        "label": "Litigation Settlement, Expense",
        "terseLabel": "Litigation Settlement, Expense"
       }
      }
     },
     "localname": "LitigationSettlementExpense",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_LondonInterbankOfferedRateLIBORMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Interest rate at which a bank borrows funds from other banks in the London interbank market.",
        "label": "London Interbank Offered Rate (LIBOR) [Member]",
        "terseLabel": "London Interbank Offered Rate (LIBOR) [Member]"
       }
      }
     },
     "localname": "LondonInterbankOfferedRateLIBORMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_LongTermDebt": {
     "auth_ref": [
      "r12",
      "r288",
      "r304",
      "r307",
      "r308",
      "r531",
      "r550"
     ],
     "calculation": {
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount, after unamortized (discount) premium and debt issuance costs, of long-term debt. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.",
        "label": "Long-term Debt",
        "terseLabel": "Carrying value of debt",
        "totalLabel": "Total carrying value of debt"
       }
      }
     },
     "localname": "LongTermDebt",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_LongTermDebtCurrent": {
     "auth_ref": [
      "r35"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 3.0,
       "parentTag": "us-gaap_LiabilitiesCurrent",
       "weight": 1.0
      },
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails": {
       "order": 1.0,
       "parentTag": "us-gaap_LongTermDebt",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount, after unamortized (discount) premium and debt issuance costs, of long-term debt, classified as current. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.",
        "label": "Long-term Debt, Current Maturities",
        "negatedLabel": "Less current portion",
        "terseLabel": "Current portion of long-term debt"
       }
      }
     },
     "localname": "LongTermDebtCurrent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_LongTermDebtMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Debt arrangement having an initial term longer than one year or beyond the normal operating cycle, if longer.",
        "label": "Long-term Debt [Member]",
        "terseLabel": "Long-term debt [Member]"
       }
      }
     },
     "localname": "LongTermDebtMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/DerivativeinstrumentsHedgedLiabilitiesandCumulativeAmountDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_LongTermDebtNoncurrent": {
     "auth_ref": [
      "r40"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 2.0,
       "parentTag": "us-gaap_LiabilitiesAndStockholdersEquity",
       "weight": 1.0
      },
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails": {
       "order": 2.0,
       "parentTag": "us-gaap_LongTermDebt",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount after unamortized (discount) premium and debt issuance costs of long-term debt classified as noncurrent and excluding amounts to be repaid within one year or the normal operating cycle, if longer. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.",
        "label": "Long-term Debt, Excluding Current Maturities",
        "terseLabel": "Total long-term debt",
        "verboseLabel": "Long-term debt"
       }
      }
     },
     "localname": "LongTermDebtNoncurrent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_LongtermDebtTypeAxis": {
     "auth_ref": [
      "r40"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by type of long-term debt.",
        "label": "Long-term Debt, Type [Axis]",
        "terseLabel": "Long-term Debt, Type [Axis]"
       }
      }
     },
     "localname": "LongtermDebtTypeAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails",
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_LongtermDebtTypeDomain": {
     "auth_ref": [
      "r40",
      "r262"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Type of long-term debt arrangement, such as notes, line of credit, commercial paper, asset-based financing, project financing, letter of credit financing. These are debt arrangements that originally required repayment more than twelve months after issuance or greater than the normal operating cycle of the company, if longer.",
        "label": "Long-term Debt, Type [Domain]",
        "terseLabel": "Long-term Debt, Type [Domain]"
       }
      }
     },
     "localname": "LongtermDebtTypeDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails",
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_LossContingenciesByNatureOfContingencyAxis": {
     "auth_ref": [
      "r251",
      "r252",
      "r253",
      "r255",
      "r256",
      "r257",
      "r258",
      "r260",
      "r261"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by type of existing condition, situation, or set of circumstances involving uncertainty as to possible loss to an enterprise that will ultimately be resolved when one or more future events occur or fail to occur.",
        "label": "Loss Contingency Nature [Axis]",
        "terseLabel": "Loss Contingency Nature [Axis]"
       }
      }
     },
     "localname": "LossContingenciesByNatureOfContingencyAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_LossContingenciesLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Loss Contingencies [Line Items]",
        "terseLabel": "Loss Contingencies [Line Items]"
       }
      }
     },
     "localname": "LossContingenciesLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_LossContingenciesTable": {
     "auth_ref": [
      "r251",
      "r252",
      "r253",
      "r255",
      "r256",
      "r257",
      "r258",
      "r260",
      "r261"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Discloses the specific components (such as the nature, name, and date) of the loss contingency and gives an estimate of the possible loss or range of loss, or states that a reasonable estimate cannot be made. Excludes environmental contingencies, warranties and unconditional purchase obligations.",
        "label": "Loss Contingencies [Table]",
        "terseLabel": "Loss Contingencies [Table]"
       }
      }
     },
     "localname": "LossContingenciesTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_LossContingencyClaimsSettledNumber": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Number of claims settled.",
        "label": "Loss Contingency, Claims Settled, Number",
        "terseLabel": "Loss Contingency, Claims Settled, Number"
       }
      }
     },
     "localname": "LossContingencyClaimsSettledNumber",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "integerItemType"
    },
    "us-gaap_LossContingencyNatureDomain": {
     "auth_ref": [
      "r251",
      "r252",
      "r253",
      "r255",
      "r256",
      "r257",
      "r258",
      "r260",
      "r261"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "An existing condition, situation, or set of circumstances involving uncertainty as to possible loss to an enterprise that will ultimately be resolved when one or more future events occur or fail to occur. Resolution of the uncertainty may confirm the incurrence of a loss or impairment of an asset or the incurrence of a liability.",
        "label": "Loss Contingency, Nature [Domain]",
        "terseLabel": "Loss Contingency, Nature [Domain]"
       }
      }
     },
     "localname": "LossContingencyNatureDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_LossContingencyNumberOfPlaintiffs": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Number of plaintiffs that have filed claims pertaining to a loss contingency.",
        "label": "Loss Contingency, Number of Plaintiffs",
        "terseLabel": "Number of plaintiffs"
       }
      }
     },
     "localname": "LossContingencyNumberOfPlaintiffs",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "integerItemType"
    },
    "us-gaap_LossContingencyPatentsAllegedlyInfringedNumber": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Number of another entity's patents that the entity has allegedly infringed.",
        "label": "Loss Contingency, Patents Allegedly Infringed, Number",
        "terseLabel": "Number of patents allegedly infringed upon"
       }
      }
     },
     "localname": "LossContingencyPatentsAllegedlyInfringedNumber",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "integerItemType"
    },
    "us-gaap_LossContingencyPendingClaimsNumber": {
     "auth_ref": [
      "r254"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Number of pending claims pertaining to a loss contingency.",
        "label": "Loss Contingency, Pending Claims, Number",
        "terseLabel": "Loss Contingency, Pending Claims, Number"
       }
      }
     },
     "localname": "LossContingencyPendingClaimsNumber",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails"
     ],
     "xbrltype": "integerItemType"
    },
    "us-gaap_MarketingRelatedIntangibleAssetsMember": {
     "auth_ref": [
      "r399"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Marketing-related asset, including, but not limited to, internet domain name, newspaper mast head, and trademark.",
        "label": "Marketing-Related Intangible Assets [Member]",
        "terseLabel": "Marketing-Related Rights [Member]"
       }
      }
     },
     "localname": "MarketingRelatedIntangibleAssetsMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge": {
     "auth_ref": [
      "r452"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Maximum period of time the entity is hedging its exposure to variability in future cash flows for forecasted transactions, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Excludes forecasted transactions related to payment of variable interest on existing financial instruments.",
        "label": "Maximum Length of Time, Foreign Currency Cash Flow Hedge",
        "terseLabel": "Length of time hedged in foreign currency contracts (or less)"
       }
      }
     },
     "localname": "MaximumLengthOfTimeForeignCurrencyCashFlowHedge",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetailsTextual"
     ],
     "xbrltype": "durationItemType"
    },
    "us-gaap_MoneyMarketFundsMember": {
     "auth_ref": [
      "r355"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fund that invests in short-term money-market instruments, for example, but not limited to, commercial paper, banker's acceptances, repurchase agreements, government securities, certificates of deposit, and other highly liquid securities.",
        "label": "Money Market Funds [Member]",
        "verboseLabel": "Money market mutual funds [Member]"
       }
      }
     },
     "localname": "MoneyMarketFundsMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_NetCashProvidedByUsedInFinancingActivities": {
     "auth_ref": [
      "r94"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 3.0,
       "parentTag": "us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of cash inflow (outflow) from financing activities, including discontinued operations. Financing activity cash flows include obtaining resources from owners and providing them with a return on, and a return of, their investment; borrowing money and repaying amounts borrowed, or settling the obligation; and obtaining and paying for other resources obtained from creditors on long-term credit.",
        "label": "Net Cash Provided by (Used in) Financing Activities",
        "totalLabel": "Net cash used in financing activities"
       }
      }
     },
     "localname": "NetCashProvidedByUsedInFinancingActivities",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Net Cash Provided by (Used in) Financing Activities [Abstract]",
        "verboseLabel": "Cash flows from financing activities:"
       }
      }
     },
     "localname": "NetCashProvidedByUsedInFinancingActivitiesAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_NetCashProvidedByUsedInInvestingActivities": {
     "auth_ref": [
      "r94"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 2.0,
       "parentTag": "us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of cash inflow (outflow) from investing activities, including discontinued operations. Investing activity cash flows include making and collecting loans and acquiring and disposing of debt or equity instruments and property, plant, and equipment and other productive assets.",
        "label": "Net Cash Provided by (Used in) Investing Activities",
        "totalLabel": "Net cash provided by (used in) investing activities"
       }
      }
     },
     "localname": "NetCashProvidedByUsedInInvestingActivities",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Net Cash Provided by (Used in) Investing Activities [Abstract]",
        "verboseLabel": "Cash flows from investing activities:"
       }
      }
     },
     "localname": "NetCashProvidedByUsedInInvestingActivitiesAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_NetCashProvidedByUsedInOperatingActivities": {
     "auth_ref": [
      "r94",
      "r95",
      "r98"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 1.0,
       "parentTag": "us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect",
       "weight": 1.0
      }
     },
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of cash inflow (outflow) from operating activities, including discontinued operations. Operating activity cash flows include transactions, adjustments, and changes in value not defined as investing or financing activities.",
        "label": "Net Cash Provided by (Used in) Operating Activities",
        "totalLabel": "Net cash provided by operating activities"
       }
      }
     },
     "localname": "NetCashProvidedByUsedInOperatingActivities",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Net Cash Provided by (Used in) Operating Activities [Abstract]",
        "verboseLabel": "Cash flows from operating activities:"
       }
      }
     },
     "localname": "NetCashProvidedByUsedInOperatingActivitiesAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_NetIncomeLoss": {
     "auth_ref": [
      "r1",
      "r60",
      "r63",
      "r68",
      "r71",
      "r98",
      "r110",
      "r120",
      "r122",
      "r123",
      "r124",
      "r125",
      "r128",
      "r129",
      "r136",
      "r163",
      "r166",
      "r168",
      "r171",
      "r173",
      "r210",
      "r263",
      "r264",
      "r265",
      "r267",
      "r268",
      "r269",
      "r270",
      "r271",
      "r272",
      "r273",
      "r458",
      "r470",
      "r536",
      "r557"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 1.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": 1.0
      },
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome": {
       "order": 1.0,
       "parentTag": "us-gaap_ComprehensiveIncomeNetOfTax",
       "weight": 1.0
      },
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.",
        "label": "Net Income (Loss) Attributable to Parent",
        "netLabel": "Net income",
        "terseLabel": "Net income for basic and diluted EPS",
        "totalLabel": "Net income",
        "verboseLabel": "Net income"
       }
      }
     },
     "localname": "NetIncomeLoss",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows",
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome",
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity",
      "http://www.amgen.com/role/EarningspershareDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_NetIncomeLossAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Net Income (Loss) Attributable to Parent [Abstract]",
        "verboseLabel": "Income (Numerator):"
       }
      }
     },
     "localname": "NetIncomeLossAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/EarningspershareDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Disclosure of accounting policy pertaining to new accounting pronouncements that may impact the entity's financial reporting. Includes, but is not limited to, quantification of the expected or actual impact.",
        "label": "New Accounting Pronouncements, Policy [Policy Text Block]",
        "terseLabel": "Other recent accounting pronouncements"
       }
      }
     },
     "localname": "NewAccountingPronouncementsPolicyPolicyTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesPolicies"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_NonUsMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Countries excluding the United States of America (US).",
        "label": "Non-US [Member]",
        "terseLabel": "ROW [Member]"
       }
      }
     },
     "localname": "NonUsMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1": {
     "auth_ref": [
      "r100",
      "r101",
      "r102"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The amount of investments that an Entity acquires in a noncash (or part noncash) acquisition. Noncash is defined as information about all investing and financing activities of an enterprise during a period that affect recognized assets or liabilities but that do not result in cash receipts or cash payments in the period. \"Part noncash\" refers to that portion of the transaction not resulting in cash receipts or cash payments in the period.",
        "label": "Noncash or Part Noncash Acquisition, Investments Acquired",
        "terseLabel": "Noncash or Part Noncash Acquisition, Investments Acquired"
       }
      }
     },
     "localname": "NoncashOrPartNoncashAcquisitionInvestmentsAcquired1",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_NondesignatedMember": {
     "auth_ref": [
      "r426"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Derivative instrument not designated as hedging instrument under Generally Accepted Accounting Principles (GAAP).",
        "label": "Not Designated as Hedging Instrument [Member]",
        "terseLabel": "Derivatives not designated as hedging instrument [Member]"
       }
      }
     },
     "localname": "NondesignatedMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_NonoperatingIncomeExpense": {
     "auth_ref": [
      "r81"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome": {
       "order": 3.0,
       "parentTag": "us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The aggregate amount of income or expense from ancillary business-related activities (that is to say, excluding major activities considered part of the normal operations of the business).",
        "label": "Nonoperating Income (Expense)",
        "terseLabel": "Other income, net"
       }
      }
     },
     "localname": "NonoperatingIncomeExpense",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_NotesPayableFairValueDisclosure": {
     "auth_ref": [
      "r36"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Fair value portion of notes payable.",
        "label": "Notes Payable, Fair Value Disclosure",
        "terseLabel": "Long-term debt, fair value"
       }
      }
     },
     "localname": "NotesPayableFairValueDisclosure",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetailsTextual"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_NotesPayableToBanksMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "A written promise to pay a note to a bank.",
        "label": "Notes Payable to Banks [Member]",
        "terseLabel": "Notes [Member]"
       }
      }
     },
     "localname": "NotesPayableToBanksMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsDetailsTextual",
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails",
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_NumberOfOperatingSegments": {
     "auth_ref": [
      "r157"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Number of operating segments. An operating segment is a component of an enterprise: (a) that engages in business activities from which it may earn revenues and incur expenses (including revenues and expenses relating to transactions with other components of the same enterprise), (b) whose operating results are regularly reviewed by the enterprise's chief operating decision maker to make decisions about resources to be allocated to the segment and assess its performance, and (c) for which discrete financial information is available. An operating segment may engage in business activities for which it has yet to earn revenues, for example, start-up operations may be operating segments before earning revenues.",
        "label": "Number of Operating Segments",
        "terseLabel": "Number of operating segments"
       }
      }
     },
     "localname": "NumberOfOperatingSegments",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails",
      "http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesDetails"
     ],
     "xbrltype": "integerItemType"
    },
    "us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent": {
     "auth_ref": [
      "r59"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount before tax and reclassification adjustments of other comprehensive income (loss) attributable to parent.",
        "label": "OCI, before Reclassifications, before Tax, Attributable to Parent",
        "terseLabel": "Unrealized gains"
       }
      }
     },
     "localname": "OciBeforeReclassificationsBeforeTaxAttributableToParent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_OperatingIncomeLoss": {
     "auth_ref": [
      "r163",
      "r166",
      "r168",
      "r171",
      "r173"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome": {
       "order": 1.0,
       "parentTag": "us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The net result for the period of deducting operating expenses from operating revenues.",
        "label": "Operating Income (Loss)",
        "totalLabel": "Operating income"
       }
      }
     },
     "localname": "OperatingIncomeLoss",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Organization, Consolidation and Presentation of Financial Statements [Abstract]",
        "terseLabel": "Organization, Consolidation and Presentation of Financial Statements [Abstract]"
       }
      }
     },
     "localname": "OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_OtherAssetsCurrent": {
     "auth_ref": [
      "r46",
      "r487"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 5.0,
       "parentTag": "us-gaap_AssetsCurrent",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of current assets classified as other.",
        "label": "Other Assets, Current",
        "verboseLabel": "Other current assets"
       }
      }
     },
     "localname": "OtherAssetsCurrent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_OtherAssetsNoncurrent": {
     "auth_ref": [
      "r33"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 5.0,
       "parentTag": "us-gaap_Assets",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of noncurrent assets classified as other.",
        "label": "Other Assets, Noncurrent",
        "verboseLabel": "Other noncurrent assets"
       }
      }
     },
     "localname": "OtherAssetsNoncurrent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent": {
     "auth_ref": [
      "r412",
      "r413",
      "r417"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome": {
       "order": 3.0,
       "parentTag": "us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount after tax and reclassification adjustments, of appreciation (loss) in value of unsold available-for-sale securities, attributable to parent entity. Excludes amounts related to other than temporary impairment (OTTI) loss.",
        "label": "Other Comprehensive Income (Loss), Available-for-sale Securities Adjustment, Net of Tax, Portion Attributable to Parent",
        "terseLabel": "(Losses) gains on available-for-sale securities"
       }
      }
     },
     "localname": "OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent": {
     "auth_ref": [
      "r412",
      "r413",
      "r417"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome": {
       "order": 1.0,
       "parentTag": "us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount after tax and reclassification adjustments of gain (loss) on foreign currency translation adjustments, foreign currency transactions designated and effective as economic hedges of a net investment in a foreign entity and intra-entity foreign currency transactions that are of a long-term-investment nature, attributable to parent entity.",
        "label": "Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent",
        "terseLabel": "(Losses) gains on foreign currency translation",
        "verboseLabel": "Foreign currency translation adjustments"
       }
      }
     },
     "localname": "OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome",
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent": {
     "auth_ref": [
      "r57"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome": {
       "order": 2.0,
       "parentTag": "us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount, after tax and reclassification, of gain (loss) from derivative instrument designated and qualifying as cash flow hedge included in assessment of hedge effectiveness, attributable to parent.",
        "label": "Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification and Tax, Parent",
        "terseLabel": "Gains (losses) on cash flow hedges"
       }
      }
     },
     "localname": "OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax": {
     "auth_ref": [
      "r52",
      "r57"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount, before tax and after reclassification, of gain (loss) from derivative instrument designated and qualifying cash flow hedge included in assessment of hedge effectiveness.",
        "label": "Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification, before Tax",
        "verboseLabel": "Total unrealized gains (losses)"
       }
      }
     },
     "localname": "OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsEffectivePortionofUnrealizedGainLossDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_OtherComprehensiveIncomeLossNetOfTax": {
     "auth_ref": [
      "r61",
      "r64",
      "r66",
      "r67",
      "r69",
      "r72",
      "r331",
      "r472",
      "r477",
      "r478",
      "r537",
      "r558"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount after tax and reclassification adjustments of other comprehensive income (loss).",
        "label": "Other Comprehensive Income (Loss), Net of Tax",
        "terseLabel": "Other comprehensive income (loss), net of taxes"
       }
      }
     },
     "localname": "OtherComprehensiveIncomeLossNetOfTax",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent": {
     "auth_ref": [
      "r61",
      "r64",
      "r412",
      "r413",
      "r417"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome": {
       "order": 2.0,
       "parentTag": "us-gaap_ComprehensiveIncomeNetOfTax",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount after tax of other comprehensive income (loss) attributable to parent entity.",
        "label": "Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent",
        "totalLabel": "Other comprehensive income (loss), net of taxes"
       }
      }
     },
     "localname": "OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract]",
        "terseLabel": "Other comprehensive income (loss), net of reclassification adjustments and taxes:"
       }
      }
     },
     "localname": "OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofComprehensiveIncome"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1": {
     "auth_ref": [
      "r412",
      "r413",
      "r417"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of tax expense (benefit) allocated to other comprehensive income (loss) attributable to parent entity.",
        "label": "Other Comprehensive Income (Loss), Tax, Portion Attributable to Parent",
        "terseLabel": "Income taxes"
       }
      }
     },
     "localname": "OtherComprehensiveIncomeLossTaxPortionAttributableToParent1",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_OtherCurrentAssetsMember": {
     "auth_ref": [
      "r428",
      "r448"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Primary financial statement caption encompassing other current assets.",
        "label": "Other Current Assets [Member]",
        "terseLabel": "Other current assets [Member]"
       }
      }
     },
     "localname": "OtherCurrentAssetsMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails",
      "http://www.amgen.com/role/DerivativeinstrumentsFairValueofDerivativesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_OtherGeneralExpense": {
     "auth_ref": [
      "r79"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome": {
       "order": 2.0,
       "parentTag": "us-gaap_CostsAndExpenses",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of general expenses not normally included in Other Operating Costs and Expenses.",
        "label": "Other General Expense",
        "verboseLabel": "Other"
       }
      }
     },
     "localname": "OtherGeneralExpense",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_OtherLiabilitiesNoncurrent": {
     "auth_ref": [
      "r41"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 4.0,
       "parentTag": "us-gaap_LiabilitiesAndStockholdersEquity",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of liabilities classified as other, due after one year or the normal operating cycle, if longer.",
        "label": "Other Liabilities, Noncurrent",
        "verboseLabel": "Other noncurrent liabilities"
       }
      }
     },
     "localname": "OtherLiabilitiesNoncurrent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_OtherLongTermDebt": {
     "auth_ref": [
      "r12",
      "r531",
      "r550"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of long-term debt classified as other.",
        "label": "Other Long-term Debt",
        "terseLabel": "Other"
       }
      }
     },
     "localname": "OtherLongTermDebt",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsPrincipalAmountsandCarryingValueofLongtermBorrowingsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_OtherNoncashIncomeExpense": {
     "auth_ref": [
      "r98"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 5.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of income (expense) included in net income that results in no cash inflow (outflow), classified as other.",
        "label": "Other Noncash Income (Expense)",
        "negatedLabel": "Other items, net"
       }
      }
     },
     "localname": "OtherNoncashIncomeExpense",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_PaymentsForProceedsFromOtherInvestingActivities": {
     "auth_ref": [
      "r85",
      "r88"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 7.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInInvestingActivities",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of cash (inflow) outflow from investing activities classified as other.",
        "label": "Payments for (Proceeds from) Other Investing Activities",
        "negatedLabel": "Other"
       }
      }
     },
     "localname": "PaymentsForProceedsFromOtherInvestingActivities",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_PaymentsForRepurchaseOfCommonStock": {
     "auth_ref": [
      "r91"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 3.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInFinancingActivities",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The cash outflow to reacquire common stock during the period.",
        "label": "Payments for Repurchase of Common Stock",
        "negatedLabel": "Repurchases of common stock"
       }
      }
     },
     "localname": "PaymentsForRepurchaseOfCommonStock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_PaymentsOfDividendsCommonStock": {
     "auth_ref": [
      "r91"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 4.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInFinancingActivities",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of cash outflow in the form of ordinary dividends to common shareholders of the parent entity.",
        "label": "Payments of Ordinary Dividends, Common Stock",
        "negatedLabel": "Dividends paid"
       }
      }
     },
     "localname": "PaymentsOfDividendsCommonStock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_PaymentsToAcquireBusinessesGross": {
     "auth_ref": [
      "r86",
      "r404"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The cash outflow associated with the acquisition of business during the period. The cash portion only of the acquisition price.",
        "label": "Payments to Acquire Businesses, Gross",
        "terseLabel": "Cash paid"
       }
      }
     },
     "localname": "PaymentsToAcquireBusinessesGross",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired": {
     "auth_ref": [
      "r86"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 1.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInInvestingActivities",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The cash outflow associated with the acquisition of a business, net of the cash acquired from the purchase.",
        "label": "Payments to Acquire Businesses, Net of Cash Acquired",
        "negatedLabel": "Payments to Acquire Businesses, Net of Cash Acquired",
        "verboseLabel": "Payments to Acquire Businesses, Net of Cash Acquired"
       }
      }
     },
     "localname": "PaymentsToAcquireBusinessesNetOfCashAcquired",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails",
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_PaymentsToAcquireEquityMethodInvestments": {
     "auth_ref": [
      "r86"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 3.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInInvestingActivities",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The cash outflow associated with the purchase of or advances to an equity method investments, which are investments in joint ventures and entities in which the entity has an equity ownership interest normally of 20 to 50 percent and exercises significant influence.",
        "label": "Payments to Acquire Equity Method Investments",
        "negatedTerseLabel": "Purchases of equity method investments",
        "terseLabel": "Payments to Acquire Equity Method Investments"
       }
      }
     },
     "localname": "PaymentsToAcquireEquityMethodInvestments",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_PaymentsToAcquireMarketableSecurities": {
     "auth_ref": [
      "r182"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 5.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInInvestingActivities",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of cash outflow for purchase of marketable security.",
        "label": "Payments to Acquire Marketable Securities",
        "negatedLabel": "Purchases of marketable securities"
       }
      }
     },
     "localname": "PaymentsToAcquireMarketableSecurities",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_PaymentsToAcquirePropertyPlantAndEquipment": {
     "auth_ref": [
      "r87"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 2.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInInvestingActivities",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The cash outflow associated with the acquisition of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale; includes cash outflows to pay for construction of self-constructed assets.",
        "label": "Payments to Acquire Property, Plant, and Equipment",
        "negatedLabel": "Purchases of property, plant and equipment"
       }
      }
     },
     "localname": "PaymentsToAcquirePropertyPlantAndEquipment",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ProceedsFromIssuanceOfLongTermDebt": {
     "auth_ref": [
      "r89"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 1.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInFinancingActivities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The cash inflow from a debt initially having maturity due after one year or beyond the operating cycle, if longer.",
        "label": "Proceeds from Issuance of Long-term Debt",
        "terseLabel": "Net proceeds from issuance of debt"
       }
      }
     },
     "localname": "ProceedsFromIssuanceOfLongTermDebt",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities": {
     "auth_ref": [
      "r83",
      "r84",
      "r182"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 6.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInInvestingActivities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of cash inflow from maturity, prepayment and call of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).",
        "label": "Proceeds from Maturities, Prepayments and Calls of Debt Securities, Available-for-sale",
        "verboseLabel": "Proceeds from maturities of marketable securities"
       }
      }
     },
     "localname": "ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ProceedsFromPaymentsForOtherFinancingActivities": {
     "auth_ref": [
      "r90",
      "r93"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 5.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInFinancingActivities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of cash inflow (outflow) from financing activities classified as other.",
        "label": "Proceeds from (Payments for) Other Financing Activities",
        "verboseLabel": "Other"
       }
      }
     },
     "localname": "ProceedsFromPaymentsForOtherFinancingActivities",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt": {
     "auth_ref": [
      "r83",
      "r84",
      "r182"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 4.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInInvestingActivities",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of cash inflow from sale of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).",
        "label": "Proceeds from Sale of Debt Securities, Available-for-sale",
        "verboseLabel": "Proceeds from sales of marketable securities"
       }
      }
     },
     "localname": "ProceedsFromSaleOfAvailableForSaleSecuritiesDebt",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ProductAndServiceOtherMember": {
     "auth_ref": [
      "r351"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Article or substance produced by nature, labor or machinery and act of providing assistance, classified as other.",
        "label": "Product and Service, Other [Member]",
        "terseLabel": "Other revenues [Member]"
       }
      }
     },
     "localname": "ProductAndServiceOtherMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_ProductMember": {
     "auth_ref": [
      "r351"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Article or substance produced by nature, labor or machinery.",
        "label": "Product [Member]",
        "terseLabel": "Product sales [Member]"
       }
      }
     },
     "localname": "ProductMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/RevenuesDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_PropertyPlantAndEquipmentNet": {
     "auth_ref": [
      "r8",
      "r9",
      "r245",
      "r487",
      "r546",
      "r554"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 2.0,
       "parentTag": "us-gaap_Assets",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount after accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business to produce goods and services and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.",
        "label": "Property, Plant and Equipment, Net",
        "verboseLabel": "Property, plant and equipment, net"
       }
      }
     },
     "localname": "PropertyPlantAndEquipmentNet",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_PropertyPlantAndEquipmentPolicyTextBlock": {
     "auth_ref": [
      "r31",
      "r245",
      "r596",
      "r597"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Disclosure of accounting policy for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections.",
        "label": "Property, Plant and Equipment, Policy [Policy Text Block]",
        "verboseLabel": "Property, plant and equipment, net"
       }
      }
     },
     "localname": "PropertyPlantAndEquipmentPolicyTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesPolicies"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Reclassification Adjustment out of Accumulated Other Comprehensive Income [Line Items]",
        "terseLabel": "Reclassification out of Accumulated Other Comprehensive Income [Line Items]"
       }
      }
     },
     "localname": "ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent": {
     "auth_ref": [
      "r59"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount before tax of reclassification adjustments of other comprehensive income (loss) attributable to parent.",
        "label": "Reclassification from AOCI, Current Period, before Tax, Attributable to Parent",
        "terseLabel": "Reclassification adjustments to income"
       }
      }
     },
     "localname": "ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis": {
     "auth_ref": [
      "r68"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by item reclassified out of accumulated other comprehensive income (loss).",
        "label": "Reclassification out of Accumulated Other Comprehensive Income [Axis]",
        "terseLabel": "Reclassification out of Accumulated Other Comprehensive Income [Axis]"
       }
      }
     },
     "localname": "ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain": {
     "auth_ref": [
      "r68"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Item reclassified out of accumulated other comprehensive income (loss).",
        "label": "Reclassification out of Accumulated Other Comprehensive Income [Domain]",
        "terseLabel": "Reclassification out of Accumulated Other Comprehensive Income [Domain]"
       }
      }
     },
     "localname": "ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember": {
     "auth_ref": [
      "r68"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Identifies item reclassified out of accumulated other comprehensive income (loss).",
        "label": "Reclassification out of Accumulated Other Comprehensive Income [Member]",
        "terseLabel": "Reclassification out of Accumulated Other Comprehensive Income [Member]"
       }
      }
     },
     "localname": "ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable": {
     "auth_ref": [
      "r68"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Disclosure of information about items reclassified out of accumulated other comprehensive income (loss).",
        "label": "Reclassification out of Accumulated Other Comprehensive Income [Table]",
        "terseLabel": "Reclassification out of Accumulated Other Comprehensive Income [Table]"
       }
      }
     },
     "localname": "ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of information about items reclassified out of accumulated other comprehensive income (loss).",
        "label": "Reclassification out of Accumulated Other Comprehensive Income [Table Text Block]",
        "terseLabel": "Reclassifications out of accumulated other comprehensive income"
       }
      }
     },
     "localname": "ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_RecoveryOfDirectCosts": {
     "auth_ref": [
      "r77"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Return of or reimbursements received in relation to direct costs and expenses previously paid or incurred.",
        "label": "Recovery of Direct Costs",
        "terseLabel": "Net costs recovered"
       }
      }
     },
     "localname": "RecoveryOfDirectCosts",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_RepaymentsOfLongTermDebt": {
     "auth_ref": [
      "r92"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 2.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInFinancingActivities",
       "weight": -1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The cash outflow for debt initially having maturity due after one year or beyond the normal operating cycle, if longer.",
        "label": "Repayments of Long-term Debt",
        "negatedLabel": "Repayment of debt"
       }
      }
     },
     "localname": "RepaymentsOfLongTermDebt",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross": {
     "auth_ref": [
      "r379",
      "r380"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The amount of costs incurred under a research and development arrangement accounted for as a contract to perform research and development for others.",
        "label": "Research and Development Arrangement, Contract to Perform for Others, Costs Incurred, Gross",
        "terseLabel": "Global research and development costs (up to)"
       }
      }
     },
     "localname": "ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff": {
     "auth_ref": [
      "r233"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows": {
       "order": 4.0,
       "parentTag": "us-gaap_NetCashProvidedByUsedInOperatingActivities",
       "weight": 1.0
      },
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome": {
       "order": 4.0,
       "parentTag": "us-gaap_CostsAndExpenses",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The amount of the write-off for research and development assets that were acquired in a transaction other than a business combination.",
        "label": "Research and Development Asset Acquired Other than Through Business Combination, Written-off",
        "terseLabel": "Acquired in-process research and development"
       }
      }
     },
     "localname": "ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails",
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofCashFlows",
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost": {
     "auth_ref": [
      "r378"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome": {
       "order": 3.0,
       "parentTag": "us-gaap_CostsAndExpenses",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The costs incurred in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, excluding in-process research and development acquired in a business combination consummated during the period. Excludes software research and development, which has a separate concept.",
        "label": "Research and Development Expense (Excluding Acquired in Process Cost)",
        "verboseLabel": "Research and development"
       }
      }
     },
     "localname": "ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_ResearchAndDevelopmentExpenseMember": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Primary financial statement caption in which the reported facts about research and development expense have been included.",
        "label": "Research and Development Expense [Member]",
        "terseLabel": "Research and Development Expense [Member]"
       }
      }
     },
     "localname": "ResearchAndDevelopmentExpenseMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_ResidentialMortgageBackedSecuritiesMember": {
     "auth_ref": [
      "r184",
      "r355"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Securities collateralized by residential real estate mortgage loans.",
        "label": "Residential Mortgage Backed Securities [Member]",
        "terseLabel": "Residential mortgage-backed securities [Member]"
       }
      }
     },
     "localname": "ResidentialMortgageBackedSecuritiesMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_RetainedEarningsAccumulatedDeficit": {
     "auth_ref": [
      "r18",
      "r338",
      "r375",
      "r487",
      "r552",
      "r572",
      "r574"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 2.0,
       "parentTag": "us-gaap_StockholdersEquity",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The cumulative amount of the reporting entity's undistributed earnings or deficit.",
        "label": "Retained Earnings (Accumulated Deficit)",
        "terseLabel": "Accumulated deficit"
       }
      }
     },
     "localname": "RetainedEarningsAccumulatedDeficit",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_RetainedEarningsMember": {
     "auth_ref": [
      "r0",
      "r116",
      "r117",
      "r118",
      "r121",
      "r127",
      "r129",
      "r211",
      "r372",
      "r373",
      "r374",
      "r387",
      "r388",
      "r456",
      "r569",
      "r571"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The cumulative amount of the reporting entity's undistributed earnings or deficit.",
        "label": "Retained Earnings [Member]",
        "terseLabel": "Accumulated deficit [Member]"
       }
      }
     },
     "localname": "RetainedEarningsMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_RevenueFromContractWithCustomerAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Revenue from Contract with Customer [Abstract]",
        "terseLabel": "Revenue from Contract with Customer [Abstract]"
       }
      }
     },
     "localname": "RevenueFromContractWithCustomerAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax": {
     "auth_ref": [
      "r158",
      "r159",
      "r165",
      "r169",
      "r170",
      "r174",
      "r175",
      "r177",
      "r348",
      "r349",
      "r524"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome": {
       "order": 1.0,
       "parentTag": "us-gaap_OperatingIncomeLoss",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.",
        "label": "Revenue from Contract with Customer, Excluding Assessed Tax",
        "terseLabel": "Total revenues"
       }
      }
     },
     "localname": "RevenueFromContractWithCustomerExcludingAssessedTax",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/RevenuesDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_RevenueFromContractWithCustomerTextBlock": {
     "auth_ref": [
      "r340",
      "r341",
      "r342",
      "r343",
      "r344",
      "r345",
      "r346",
      "r347",
      "r350",
      "r353"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure of revenue from contract with customer to transfer good or service and to transfer nonfinancial asset. Includes, but is not limited to, disaggregation of revenue, credit loss recognized from contract with customer, judgment and change in judgment related to contract with customer, and asset recognized from cost incurred to obtain or fulfill contract with customer. Excludes insurance and lease contracts.",
        "label": "Revenue from Contract with Customer [Text Block]",
        "terseLabel": "Revenues"
       }
      }
     },
     "localname": "RevenueFromContractWithCustomerTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/Revenues"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_RevenuesAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Revenues [Abstract]",
        "verboseLabel": "Revenues:"
       }
      }
     },
     "localname": "RevenuesAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock": {
     "auth_ref": [
      "r59",
      "r477",
      "r478"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of the components of accumulated other comprehensive income (loss).",
        "label": "Schedule of Accumulated Other Comprehensive Income (Loss) [Table Text Block]",
        "terseLabel": "Components of accumulated other comprehensive income"
       }
      }
     },
     "localname": "ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Debt Securities, Available-for-sale [Line Items]",
        "terseLabel": "Debt Securities, Available-for-sale [Line Items]"
       }
      }
     },
     "localname": "ScheduleOfAvailableForSaleSecuritiesLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsDetails",
      "http://www.amgen.com/role/InvestmentsEquitySecuritiesDetailsTextual",
      "http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_ScheduleOfAvailableForSaleSecuritiesTable": {
     "auth_ref": [
      "r190",
      "r192",
      "r195",
      "r196",
      "r197",
      "r199",
      "r541",
      "r542"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Schedule of available-for-sale securities which includes, but is not limited to, changes in the cost basis and fair value, fair value and gross unrealized gain (loss), fair values by type of security, contractual maturity and classification, amortized cost basis, contracts to acquire securities to be accounted for as available-for-sale, debt maturities, transfers to trading, change in net unrealized holding gain (loss) net of tax, continuous unrealized loss position fair value, aggregate losses qualitative disclosures, other than temporary impairment (OTTI) losses or other disclosures related to available for sale securities.",
        "label": "Schedule of Available-for-sale Securities [Table]",
        "terseLabel": "Schedule of Available-for-sale Securities [Table]"
       }
      }
     },
     "localname": "ScheduleOfAvailableForSaleSecuritiesTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsDetails",
      "http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable": {
     "auth_ref": [
      "r396",
      "r397"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Schedule reflecting each material business combination (or series of individually immaterial business combinations) completed during the period, including background, timing, and recognized assets and liabilities.",
        "label": "Schedule of Business Acquisitions, by Acquisition [Table]",
        "terseLabel": "Schedule of Business Acquisitions, by Acquisition [Table]"
       }
      }
     },
     "localname": "ScheduleOfBusinessAcquisitionsByAcquisitionTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/BusinessCombinationsandAssetAcquisitionsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock": {
     "auth_ref": [
      "r436"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of gain (loss) on derivative and nonderivative instruments designated and qualifying as cash flow hedge recorded in accumulated other comprehensive income (AOCI) and reclassified into earnings.",
        "label": "Schedule of Cash Flow Hedges Included in Accumulated Other Comprehensive Income (Loss) [Table Text Block]",
        "verboseLabel": "Unrealized gain (loss) recognized in Other Comprehensive Income for our derivative instruments designated as cash flow hedges"
       }
      }
     },
     "localname": "ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable": {
     "auth_ref": [
      "r410"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Disclosure of information about collaborative arrangement and arrangement other than collaborative applicable to revenue-generating activity or operations.",
        "label": "Collaborative Arrangement and Arrangement Other than Collaborative [Table]",
        "terseLabel": "Collaborative Arrangement and Arrangement Other than Collaborative [Table]"
       }
      }
     },
     "localname": "ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_ScheduleOfDebtInstrumentsTextBlock": {
     "auth_ref": [
      "r40",
      "r114",
      "r307",
      "r309",
      "r332",
      "r335",
      "r336",
      "r337",
      "r480",
      "r481",
      "r484",
      "r547"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of long-debt instruments or arrangements, including identification, terms, features, collateral requirements and other information necessary to a fair presentation. These are debt arrangements that originally required repayment more than twelve months after issuance or greater than the normal operating cycle of the entity, if longer.",
        "label": "Schedule of Long-term Debt Instruments [Table Text Block]",
        "verboseLabel": "Schedule of borrowings"
       }
      }
     },
     "localname": "ScheduleOfDebtInstrumentsTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock": {
     "auth_ref": [
      "r434"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of the location and fair value amounts of derivative instruments (and nonderivative instruments that are designated and qualify as hedging instruments) reported in the statement of financial position.",
        "label": "Schedule of Derivative Instruments in Statement of Financial Position, Fair Value [Table Text Block]",
        "verboseLabel": "Fair values of derivatives included in the Condensed Consolidated Balance Sheets"
       }
      }
     },
     "localname": "ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock": {
     "auth_ref": [
      "r430"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of derivative instruments (including nonderivative instruments that are designated and qualify as hedging instruments) of (a) the location and amount of gains and losses reported in the statement of financial performance and (b) the location and fair value amounts of the instruments reported in the statement of financial position.",
        "label": "Schedule of Derivatives Instruments Statements of Financial Performance and Financial Position, Location [Table Text Block]",
        "terseLabel": "Summary of amounts of income and expense line items"
       }
      }
     },
     "localname": "ScheduleOfDerivativesInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock": {
     "auth_ref": [
      "r139"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of an entity's basic and diluted earnings per share calculations, including a reconciliation of numerators and denominators of the basic and diluted per-share computations for income from continuing operations.",
        "label": "Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]",
        "verboseLabel": "Computation for basic and diluted earnings per share"
       }
      }
     },
     "localname": "ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/EarningspershareTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable": {
     "auth_ref": [
      "r174"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular presentation of the description and amount of revenues from a product or service, or a group of similar products or similar services, reported from external customers during the period, if the information is not provided as part of the reportable operating segment information.",
        "label": "Revenue from External Customers by Products and Services [Table]",
        "terseLabel": "Revenue from External Customers by Products and Services [Table]"
       }
      }
     },
     "localname": "ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/RevenuesDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock": {
     "auth_ref": [
      "r461",
      "r462"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of assets and liabilities, including [financial] instruments measured at fair value that are classified in stockholders' equity, if any, that are measured at fair value on a recurring basis. The disclosures contemplated herein include the fair value measurements at the reporting date by the level within the fair value hierarchy in which the fair value measurements in their entirety fall, segregating fair value measurements using quoted prices in active markets for identical assets (Level 1), significant other observable inputs (Level 2), and significant unobservable inputs (Level 3).",
        "label": "Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]",
        "terseLabel": "Fair value of each major class of financial assets and liabilities measured at fair value on a recurring basis"
       }
      }
     },
     "localname": "ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock": {
     "auth_ref": [
      "r435"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure for fair value hedging instruments of (a) the location and amount of gains and losses reported in the statement of financial performance and (b) the location and fair value amounts of the instruments reported in the statement of financial position.",
        "label": "Schedule of Fair Value Hedging Instruments, Statements of Financial Performance and Financial Position, Location [Table Text Block]",
        "terseLabel": "Derivatives in fair value hedging relationships"
       }
      }
     },
     "localname": "ScheduleOfFairValueHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/DerivativeinstrumentsTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable": {
     "auth_ref": [
      "r231",
      "r236",
      "r525"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Schedule of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.",
        "label": "Schedule of Finite-Lived Intangible Assets [Table]",
        "terseLabel": "Schedule of Finite-Lived Intangible Assets [Table]"
       }
      }
     },
     "localname": "ScheduleOfFiniteLivedIntangibleAssetsTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_ScheduleOfGoodwillTextBlock": {
     "auth_ref": [
      "r227",
      "r228"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of goodwill by reportable segment and in total which includes a rollforward schedule.",
        "label": "Schedule of Goodwill [Table Text Block]",
        "terseLabel": "Schedule of goodwill"
       }
      }
     },
     "localname": "ScheduleOfGoodwillTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable": {
     "auth_ref": [
      "r240",
      "r242"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Schedule of assets, excluding financial assets and goodwill, lacking physical substance and exist in perpetuity.",
        "label": "Schedule of Indefinite-Lived Intangible Assets [Table]",
        "terseLabel": "Schedule of Indefinite-Lived Intangible Assets [Table]"
       }
      }
     },
     "localname": "ScheduleOfIndefiniteLivedIntangibleAssetsTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/GoodwillandotherintangibleassetsIdentifiableIntangibleAssetsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_ScheduleOfInterestRateDerivativesTableTextBlock": {
     "auth_ref": [
      "r437"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of interest rate derivatives, including, but not limited to, the fair value of the derivatives, statement of financial position location, and statement of financial performance location of these instruments.",
        "label": "Schedule of Interest Rate Derivatives [Table Text Block]",
        "terseLabel": "Schedule of interest rate swaps"
       }
      }
     },
     "localname": "ScheduleOfInterestRateDerivativesTableTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_ScheduleOfInventoryCurrentTableTextBlock": {
     "auth_ref": [
      "r7",
      "r26",
      "r27",
      "r28"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Tabular disclosure of the carrying amount as of the balance sheet date of merchandise, goods, commodities, or supplies held for future sale or to be used in manufacturing, servicing or production process.",
        "label": "Schedule of Inventory, Current [Table Text Block]",
        "verboseLabel": "Inventories"
       }
      }
     },
     "localname": "ScheduleOfInventoryCurrentTableTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InventoriesTables"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Net Investment Income [Line Items]",
        "terseLabel": "Net Investment Income [Line Items]"
       }
      }
     },
     "localname": "ScheduleOfInvestmentIncomeReportedAmountsByCategoryLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable": {
     "auth_ref": [
      "r80",
      "r82",
      "r563"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Disclosure of information about investment income, including, but not limited to, interest and dividend income and amortization of discount (premium) derived from debt and equity securities. Excludes realized and unrealized gain (loss) on investments.",
        "label": "Investment Income [Table]",
        "terseLabel": "Investment Income [Table]"
       }
      }
     },
     "localname": "ScheduleOfInvestmentIncomeReportedAmountsByCategoryTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_ScheduleOfStockByClassTable": {
     "auth_ref": [
      "r43",
      "r107",
      "r147",
      "r148",
      "r312",
      "r313",
      "r314",
      "r315",
      "r316",
      "r317",
      "r318",
      "r320",
      "r324",
      "r329",
      "r332",
      "r333",
      "r334",
      "r335",
      "r336",
      "r337",
      "r338"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Schedule detailing information related to equity by class of stock. Class of stock includes common, convertible, and preferred stocks which are not redeemable or redeemable solely at the option of the issuer. It also includes preferred stock with redemption features that are solely within the control of the issuer and mandatorily redeemable stock if redemption is required to occur only upon liquidation or termination of the reporting entity.",
        "label": "Schedule of Stock by Class [Table]",
        "terseLabel": "Schedule of Stock by Class [Table]"
       }
      }
     },
     "localname": "ScheduleOfStockByClassTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityDetailsTextualDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_SellingGeneralAndAdministrativeExpense": {
     "auth_ref": [
      "r78"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome": {
       "order": 5.0,
       "parentTag": "us-gaap_CostsAndExpenses",
       "weight": 1.0
      }
     },
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The aggregate total costs related to selling a firm's product and services, as well as all other general and administrative expenses. Direct selling expenses (for example, credit, warranty, and advertising) are expenses that can be directly linked to the sale of specific products. Indirect selling expenses are expenses that cannot be directly linked to the sale of specific products, for example telephone expenses, Internet, and postal charges. General and administrative expenses include salaries of non-sales personnel, rent, utilities, communication, etc.",
        "label": "Selling, General and Administrative Expense",
        "verboseLabel": "Selling, general and administrative"
       }
      }
     },
     "localname": "SellingGeneralAndAdministrativeExpense",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_SignificantAccountingPoliciesTextBlock": {
     "auth_ref": [
      "r104",
      "r115"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure for all significant accounting policies of the reporting entity.",
        "label": "Significant Accounting Policies [Text Block]",
        "verboseLabel": "Summary of significant accounting policies"
       }
      }
     },
     "localname": "SignificantAccountingPoliciesTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/Summaryofsignificantaccountingpolicies"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_StatementClassOfStockAxis": {
     "auth_ref": [
      "r13",
      "r14",
      "r15",
      "r107",
      "r110",
      "r133",
      "r134",
      "r135",
      "r137",
      "r139",
      "r147",
      "r148",
      "r149",
      "r210",
      "r263",
      "r267",
      "r268",
      "r269",
      "r272",
      "r273",
      "r315",
      "r316",
      "r320",
      "r324",
      "r331",
      "r470",
      "r614"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by the different classes of stock of the entity.",
        "label": "Class of Stock [Axis]",
        "terseLabel": "Class of Stock [Axis]"
       }
      }
     },
     "localname": "StatementClassOfStockAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CoverPage"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_StatementEquityComponentsAxis": {
     "auth_ref": [
      "r0",
      "r44",
      "r66",
      "r67",
      "r68",
      "r116",
      "r117",
      "r118",
      "r121",
      "r127",
      "r129",
      "r146",
      "r211",
      "r331",
      "r338",
      "r372",
      "r373",
      "r374",
      "r387",
      "r388",
      "r456",
      "r472",
      "r473",
      "r474",
      "r475",
      "r476",
      "r478",
      "r569",
      "r570",
      "r571",
      "r624"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by component of equity.",
        "label": "Equity Components [Axis]",
        "terseLabel": "Equity Components [Axis]"
       }
      }
     },
     "localname": "StatementEquityComponentsAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity",
      "http://www.amgen.com/role/DerivativeinstrumentsSummaryofIncomeandExpenseLineItemsDetails",
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails",
      "http://www.amgen.com/role/StockholdersequityReclassificationsoutofAOCIDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_StatementLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.",
        "label": "Statement [Line Items]",
        "terseLabel": "Statement [Line Items]"
       }
      }
     },
     "localname": "StatementLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_StatementOfCashFlowsAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Statement of Cash Flows [Abstract]",
        "terseLabel": "Statement of Cash Flows [Abstract]"
       }
      }
     },
     "localname": "StatementOfCashFlowsAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_StatementOfFinancialPositionAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Statement of Financial Position [Abstract]",
        "terseLabel": "Statement of Financial Position [Abstract]"
       }
      }
     },
     "localname": "StatementOfFinancialPositionAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Statement of Comprehensive Income [Abstract]",
        "terseLabel": "Statement of Comprehensive Income [Abstract]"
       }
      }
     },
     "localname": "StatementOfIncomeAndComprehensiveIncomeAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_StatementOfStockholdersEquityAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Statement of Stockholders' Equity [Abstract]",
        "terseLabel": "Statement of Stockholders' Equity [Abstract]"
       }
      }
     },
     "localname": "StatementOfStockholdersEquityAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_StatementTable": {
     "auth_ref": [
      "r116",
      "r117",
      "r118",
      "r146",
      "r524"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Schedule reflecting a Statement of Income, Statement of Cash Flows, Statement of Financial Position, Statement of Shareholders' Equity and Other Comprehensive Income, or other statement as needed.",
        "label": "Statement [Table]",
        "terseLabel": "Statement [Table]"
       }
      }
     },
     "localname": "StatementTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation": {
     "auth_ref": [
      "r14",
      "r15",
      "r331",
      "r338"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Number, after forfeiture, of shares or units issued under share-based payment arrangement. Excludes shares or units issued under employee stock ownership plan (ESOP).",
        "label": "Shares Issued, Shares, Share-based Payment Arrangement, after Forfeiture",
        "verboseLabel": "Issuance of common stock in connection with the Company\u2019s equity award programs, Shares"
       }
      }
     },
     "localname": "StockIssuedDuringPeriodSharesShareBasedCompensation",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "sharesItemType"
    },
    "us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation": {
     "auth_ref": [
      "r14",
      "r15",
      "r338",
      "r370",
      "r371"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Value, after forfeiture, of shares issued under share-based payment arrangement. Excludes employee stock ownership plan (ESOP).",
        "label": "Shares Issued, Value, Share-based Payment Arrangement, after Forfeiture",
        "terseLabel": "Issuance of common stock in connection with the Company\u2019s equity award programs"
       }
      }
     },
     "localname": "StockIssuedDuringPeriodValueShareBasedCompensation",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_StockRepurchaseProgramAuthorizedAmount1": {
     "auth_ref": [],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of stock repurchase plan authorized.",
        "label": "Stock Repurchase Program, Authorized Amount",
        "terseLabel": "Stock repurchase program, additional authorized amount"
       }
      }
     },
     "localname": "StockRepurchaseProgramAuthorizedAmount1",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityDetailsTextualDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1": {
     "auth_ref": [],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount remaining of a stock repurchase plan authorized.",
        "label": "Stock Repurchase Program, Remaining Authorized Repurchase Amount",
        "verboseLabel": "Amount available for stock repurchases under a board approved stock repurchase plan"
       }
      }
     },
     "localname": "StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityDetailsTextualDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_StockRepurchasedAndRetiredDuringPeriodShares": {
     "auth_ref": [
      "r14",
      "r15",
      "r331",
      "r338"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Number of shares that have been repurchased and retired during the period.",
        "label": "Stock Repurchased and Retired During Period, Shares",
        "negatedTerseLabel": "Repurchases of common stock, Shares"
       }
      }
     },
     "localname": "StockRepurchasedAndRetiredDuringPeriodShares",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "sharesItemType"
    },
    "us-gaap_StockRepurchasedAndRetiredDuringPeriodValue": {
     "auth_ref": [
      "r14",
      "r15",
      "r331",
      "r338"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Equity impact of the value of stock that has been repurchased and retired during the period. The excess of the purchase price over par value can be charged against retained earnings (once the excess is fully allocated to additional paid in capital).",
        "label": "Stock Repurchased and Retired During Period, Value",
        "negatedTerseLabel": "Repurchases of common stock"
       }
      }
     },
     "localname": "StockRepurchasedAndRetiredDuringPeriodValue",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_StockRepurchasedDuringPeriodShares": {
     "auth_ref": [
      "r14",
      "r15",
      "r331",
      "r338"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Number of shares that have been repurchased during the period and have not been retired and are not held in treasury. Some state laws may govern the circumstances under which an entity may acquire its own stock and prescribe the accounting treatment therefore. This element is used when state law does not recognize treasury stock.",
        "label": "Stock Repurchased During Period, Shares",
        "terseLabel": "Stock repurchased, Shares"
       }
      }
     },
     "localname": "StockRepurchasedDuringPeriodShares",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityShareRepurchaseProgramDetails"
     ],
     "xbrltype": "sharesItemType"
    },
    "us-gaap_StockRepurchasedDuringPeriodValue": {
     "auth_ref": [
      "r14",
      "r15",
      "r331",
      "r338"
     ],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Equity impact of the value of stock that has been repurchased during the period and has not been retired and is not held in treasury. Some state laws may mandate the circumstances under which an entity may acquire its own stock and prescribe the accounting treatment therefore. This element is used when state law does not recognize treasury stock.",
        "label": "Stock Repurchased During Period, Value",
        "terseLabel": "Stock repurchased"
       }
      }
     },
     "localname": "StockRepurchasedDuringPeriodValue",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/StockholdersequityShareRepurchaseProgramDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_StockholdersEquity": {
     "auth_ref": [
      "r15",
      "r20",
      "r21",
      "r110",
      "r180",
      "r210",
      "r470",
      "r487"
     ],
     "calculation": {
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets": {
       "order": 5.0,
       "parentTag": "us-gaap_LiabilitiesAndStockholdersEquity",
       "weight": 1.0
      }
     },
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Total of all stockholders' equity (deficit) items, net of receivables from officers, directors, owners, and affiliates of the entity which are attributable to the parent. The amount of the economic entity's stockholders' equity attributable to the parent excludes the amount of stockholders' equity which is allocable to that ownership interest in subsidiary equity which is not attributable to the parent (noncontrolling interest, minority interest). This excludes temporary equity and is sometimes called permanent equity.",
        "label": "Stockholders' Equity Attributable to Parent",
        "periodEndLabel": "Balance as of end of period",
        "periodStartLabel": "Balance as of beginning of period",
        "totalLabel": "Total stockholders\u2019 equity"
       }
      }
     },
     "localname": "StockholdersEquity",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets",
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity",
      "http://www.amgen.com/role/StockholdersequityComponentsofAOCIDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_StockholdersEquityAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Stockholders' Equity Attributable to Parent [Abstract]",
        "verboseLabel": "Stockholders\u2019 equity:"
       }
      }
     },
     "localname": "StockholdersEquityAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedBalanceSheets"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_StockholdersEquityNoteDisclosureTextBlock": {
     "auth_ref": [
      "r108",
      "r316",
      "r319",
      "r320",
      "r321",
      "r322",
      "r323",
      "r324",
      "r325",
      "r326",
      "r327",
      "r328",
      "r330",
      "r338",
      "r339"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure for shareholders' equity comprised of portions attributable to the parent entity and noncontrolling interest, including other comprehensive income. Includes, but is not limited to, balances of common stock, preferred stock, additional paid-in capital, other capital and retained earnings, accumulated balance for each classification of other comprehensive income and amount of comprehensive income.",
        "label": "Stockholders' Equity Note Disclosure [Text Block]",
        "verboseLabel": "Stockholders' equity"
       }
      }
     },
     "localname": "StockholdersEquityNoteDisclosureTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/Stockholdersequity"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_StockholdersEquityOther": {
     "auth_ref": [],
     "crdr": "debit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "This element represents movements included in the statement of changes in stockholders' equity which are not separately disclosed or provided for elsewhere in the taxonomy.",
        "label": "Stockholders' Equity, Other",
        "terseLabel": "Other"
       }
      }
     },
     "localname": "StockholdersEquityOther",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofStockholdersEquity"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_SubsequentEventLineItems": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Detail information of subsequent event by type. User is expected to use existing line items from elsewhere in the taxonomy as the primary line items for this disclosure, which is further associated with dimension and member elements pertaining to a subsequent event.",
        "label": "Subsequent Event [Line Items]",
        "terseLabel": "Subsequent Event [Line Items]"
       }
      }
     },
     "localname": "SubsequentEventLineItems",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_SubsequentEventMember": {
     "auth_ref": [
      "r479",
      "r489"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Identifies event that occurred after the balance sheet date but before financial statements are issued or available to be issued.",
        "label": "Subsequent Event [Member]",
        "terseLabel": "Subsequent Event [Member]"
       }
      }
     },
     "localname": "SubsequentEventMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails",
      "http://www.amgen.com/role/StockholdersequityDetailsTextualDetails",
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_SubsequentEventTable": {
     "auth_ref": [
      "r479",
      "r489"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Discloses pertinent information about one or more significant events or transactions that occurred after the balance sheet date through the date the financial statements were issued or the date the financial statements were available to be issued.",
        "label": "Subsequent Event [Table]",
        "terseLabel": "Subsequent Event [Table]"
       }
      }
     },
     "localname": "SubsequentEventTable",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_SubsequentEventTypeAxis": {
     "auth_ref": [
      "r479",
      "r489"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by event that occurred after the balance sheet date but before financial statements are issued or available to be issued.",
        "label": "Subsequent Event Type [Axis]",
        "terseLabel": "Subsequent Event Type [Axis]"
       }
      }
     },
     "localname": "SubsequentEventTypeAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails",
      "http://www.amgen.com/role/StockholdersequityDetailsTextualDetails",
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_SubsequentEventTypeDomain": {
     "auth_ref": [
      "r479",
      "r489"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Event that occurred after the balance sheet date but before financial statements are issued or available to be issued.",
        "label": "Subsequent Event Type [Domain]",
        "terseLabel": "Subsequent Event Type [Domain]"
       }
      }
     },
     "localname": "SubsequentEventTypeDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/ContingenciesandcommitmentsDetails",
      "http://www.amgen.com/role/InvestmentsInvestmentsLimitedPartnershipInvestmentsDetails",
      "http://www.amgen.com/role/StockholdersequityDetailsTextualDetails",
      "http://www.amgen.com/role/SubsequenteventsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_SubsequentEventsAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Subsequent Events [Abstract]"
       }
      }
     },
     "localname": "SubsequentEventsAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "xbrltype": "stringItemType"
    },
    "us-gaap_SubsequentEventsTextBlock": {
     "auth_ref": [
      "r488",
      "r491"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The entire disclosure for significant events or transactions that occurred after the balance sheet date through the date the financial statements were issued or the date the financial statements were available to be issued. Examples include: the sale of a capital stock issue, purchase of a business, settlement of litigation, catastrophic loss, significant foreign exchange rate changes, loans to insiders or affiliates, and transactions not in the ordinary course of business.",
        "label": "Subsequent Events [Text Block]",
        "terseLabel": "Subsequent events"
       }
      }
     },
     "localname": "SubsequentEventsTextBlock",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/Subsequentevents"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain": {
     "auth_ref": [
      "r193",
      "r194",
      "r201",
      "r202",
      "r203",
      "r300",
      "r329",
      "r453",
      "r492",
      "r493",
      "r494",
      "r495",
      "r496",
      "r497",
      "r498",
      "r499",
      "r500",
      "r501",
      "r502",
      "r503",
      "r504",
      "r506",
      "r507",
      "r508",
      "r509",
      "r510",
      "r511",
      "r512",
      "r513",
      "r514",
      "r515",
      "r516",
      "r517",
      "r518",
      "r519",
      "r520",
      "r521",
      "r522",
      "r614",
      "r615",
      "r616",
      "r617",
      "r618",
      "r619",
      "r620"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Instrument or contract that imposes a contractual obligation to deliver cash or another financial instrument or to exchange other financial instruments on potentially unfavorable terms and conveys a contractual right to receive cash or another financial instrument or to exchange other financial instruments on potentially favorable terms.",
        "label": "Financial Instruments [Domain]",
        "terseLabel": "Financial Instruments [Domain]"
       }
      }
     },
     "localname": "TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsDetails",
      "http://www.amgen.com/role/InvestmentsFairValuesbyClassificationDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_TypeOfArrangementAxis": {
     "auth_ref": [
      "r410"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by collaborative arrangement and arrangement other than collaborative applicable to revenue-generating activity or operations.",
        "label": "Collaborative Arrangement and Arrangement Other than Collaborative [Axis]",
        "terseLabel": "Collaborative Arrangement and Arrangement Other than Collaborative [Axis]"
       }
      }
     },
     "localname": "TypeOfArrangementAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CollaborationsDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_USGovernmentAgenciesDebtSecuritiesMember": {
     "auth_ref": [
      "r113",
      "r355",
      "r540"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Debentures, notes, and other debt securities issued by US government agencies, for example, but not limited to, Government National Mortgage Association (GNMA or Ginnie Mae). Excludes US treasury securities and debt issued by government-sponsored Enterprises (GSEs), for example, but is not limited to, Federal Home Loan Mortgage Corporation (FHLMC or Freddie Mac), Federal National Mortgage Association (FNMA or Fannie Mae), and the Federal Home Loan Bank (FHLB).",
        "label": "US Government Agencies Debt Securities [Member]",
        "terseLabel": "Other government-related debt securities - U.S. [Member]"
       }
      }
     },
     "localname": "USGovernmentAgenciesDebtSecuritiesMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_USTreasuryBillSecuritiesMember": {
     "auth_ref": [
      "r540"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "This category includes information about negotiable debt securities issued by the United States Department of the Treasury which generally have maturities of one year or less, are interest bearing, and are backed by the full faith and credit of the United States government.",
        "label": "US Treasury Bill Securities [Member]",
        "terseLabel": "U.S. Treasury bills [Member]"
       }
      }
     },
     "localname": "USTreasuryBillSecuritiesMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_USTreasurySecuritiesMember": {
     "auth_ref": [
      "r113",
      "r355",
      "r362",
      "r540"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "This category includes information about debt securities issued by the United States Department of the Treasury and backed by the United States government. Such securities primarily consist of treasury bills (short-term maturities - one year or less), treasury notes (intermediate term maturities - two to ten years), and treasury bonds (long-term maturities - ten to thirty years).",
        "label": "US Treasury Securities [Member]",
        "terseLabel": "U.S. Treasury notes [Member]"
       }
      }
     },
     "localname": "USTreasurySecuritiesMember",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FairvaluemeasurementDetails",
      "http://www.amgen.com/role/InvestmentsDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions": {
     "auth_ref": [
      "r384"
     ],
     "crdr": "credit",
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Amount of increase in unrecognized tax benefits resulting from tax positions that have been or will be taken in current period tax return.",
        "label": "Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions",
        "terseLabel": "Increase in unrecognized tax benefits resulting from tax positions taken during the current period"
       }
      }
     },
     "localname": "UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/IncometaxesDetails"
     ],
     "xbrltype": "monetaryItemType"
    },
    "us-gaap_UseOfEstimates": {
     "auth_ref": [
      "r150",
      "r151",
      "r152",
      "r153",
      "r154",
      "r155",
      "r156"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Disclosure of accounting policy for the use of estimates in the preparation of financial statements in conformity with generally accepted accounting principles.",
        "label": "Use of Estimates, Policy [Policy Text Block]",
        "verboseLabel": "Use of estimates"
       }
      }
     },
     "localname": "UseOfEstimates",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/SummaryofsignificantaccountingpoliciesPolicies"
     ],
     "xbrltype": "textBlockItemType"
    },
    "us-gaap_VariableRateAxis": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Information by type of variable rate.",
        "label": "Variable Rate [Axis]",
        "terseLabel": "Variable Rate [Axis]"
       }
      }
     },
     "localname": "VariableRateAxis",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_VariableRateDomain": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Interest rate that fluctuates over time as a result of an underlying benchmark interest rate or index.",
        "label": "Variable Rate [Domain]",
        "terseLabel": "Variable Rate [Domain]"
       }
      }
     },
     "localname": "VariableRateDomain",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/FinancingarrangementsinterestrateswapstextualinterimonlyDetails"
     ],
     "xbrltype": "domainItemType"
    },
    "us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment": {
     "auth_ref": [
      "r139"
     ],
     "calculation": {
      "http://www.amgen.com/role/EarningspershareDetails": {
       "order": 1.0,
       "parentTag": "us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding",
       "weight": 1.0
      }
     },
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The sum of dilutive potential common shares or units used in the calculation of the diluted per-share or per-unit computation.",
        "label": "Weighted Average Number Diluted Shares Outstanding Adjustment",
        "verboseLabel": "Effect of dilutive securities (in shares)"
       }
      }
     },
     "localname": "WeightedAverageNumberDilutedSharesOutstandingAdjustment",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/EarningspershareDetails"
     ],
     "xbrltype": "sharesItemType"
    },
    "us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding": {
     "auth_ref": [
      "r132",
      "r139"
     ],
     "calculation": {
      "http://www.amgen.com/role/EarningspershareDetails": {
       "order": null,
       "parentTag": null,
       "root": true,
       "weight": null
      }
     },
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The average number of shares or units issued and outstanding that are used in calculating diluted EPS or earnings per unit (EPU), determined based on the timing of issuance of shares or units in the period.",
        "label": "Weighted Average Number of Shares Outstanding, Diluted",
        "totalLabel": "Weighted-average shares for diluted EPS (in shares)",
        "verboseLabel": "Diluted (in shares)"
       }
      }
     },
     "localname": "WeightedAverageNumberOfDilutedSharesOutstanding",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/EarningspershareDetails"
     ],
     "xbrltype": "sharesItemType"
    },
    "us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "label": "Weighted Average Number of Shares Outstanding, Diluted [Abstract]",
        "terseLabel": "Shares (Denominator):",
        "verboseLabel": "Shares used in calculation of earnings per share:"
       }
      }
     },
     "localname": "WeightedAverageNumberOfSharesOutstandingAbstract",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/EarningspershareDetails"
     ],
     "xbrltype": "stringItemType"
    },
    "us-gaap_WeightedAverageNumberOfSharesOutstandingBasic": {
     "auth_ref": [
      "r131",
      "r139"
     ],
     "calculation": {
      "http://www.amgen.com/role/EarningspershareDetails": {
       "order": 2.0,
       "parentTag": "us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding",
       "weight": 1.0
      }
     },
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Number of [basic] shares or units, after adjustment for contingently issuable shares or units and other shares or units not deemed outstanding, determined by relating the portion of time within a reporting period that common shares or units have been outstanding to the total time in that period.",
        "label": "Weighted Average Number of Shares Outstanding, Basic",
        "terseLabel": "Weighted-average shares for basic EPS (in shares)",
        "verboseLabel": "Basic (in shares)"
       }
      }
     },
     "localname": "WeightedAverageNumberOfSharesOutstandingBasic",
     "nsuri": "http://fasb.org/us-gaap/2021-01-31",
     "presentation": [
      "http://www.amgen.com/role/CondensedConsolidatedStatementsofIncome",
      "http://www.amgen.com/role/EarningspershareDetails"
     ],
     "xbrltype": "sharesItemType"
    }
   },
   "unitCount": 10
  }
 },
 "std_ref": {
  "r0": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "6",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "105",
   "URI": "http://asc.fasb.org/extlink&oid=124434974&loc=SL124442142-165695"
  },
  "r1": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "205",
   "URI": "http://asc.fasb.org/extlink&oid=109222650&loc=SL51721683-107760"
  },
  "r10": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(19))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r100": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123431023&loc=d3e4304-108586"
  },
  "r101": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123431023&loc=d3e4313-108586"
  },
  "r102": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123431023&loc=d3e4332-108586"
  },
  "r103": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "8",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123431023&loc=SL98516268-108586"
  },
  "r104": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "235",
   "URI": "http://asc.fasb.org/extlink&oid=123372394&loc=d3e18726-107790"
  },
  "r105": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "235",
   "URI": "http://asc.fasb.org/extlink&oid=123372394&loc=d3e18823-107790"
  },
  "r106": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.4-08(c))",
   "Topic": "235",
   "URI": "http://asc.fasb.org/extlink&oid=120395691&loc=d3e23780-122690"
  },
  "r107": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.4-08(d))",
   "Topic": "235",
   "URI": "http://asc.fasb.org/extlink&oid=120395691&loc=d3e23780-122690"
  },
  "r108": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.4-08(e)(1))",
   "Topic": "235",
   "URI": "http://asc.fasb.org/extlink&oid=120395691&loc=d3e23780-122690"
  },
  "r109": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.4-08(f))",
   "Topic": "235",
   "URI": "http://asc.fasb.org/extlink&oid=120395691&loc=d3e23780-122690"
  },
  "r11": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(20))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r110": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.4-08(g)(1)(ii))",
   "Topic": "235",
   "URI": "http://asc.fasb.org/extlink&oid=120395691&loc=d3e23780-122690"
  },
  "r111": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.4-08(h)(2))",
   "Topic": "235",
   "URI": "http://asc.fasb.org/extlink&oid=120395691&loc=d3e23780-122690"
  },
  "r112": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.4-08(h))",
   "Topic": "235",
   "URI": "http://asc.fasb.org/extlink&oid=120395691&loc=d3e23780-122690"
  },
  "r113": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.4-08(m)(1)(ii)(A))",
   "Topic": "235",
   "URI": "http://asc.fasb.org/extlink&oid=120395691&loc=d3e23780-122690"
  },
  "r114": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.12-04(a))",
   "Topic": "235",
   "URI": "http://asc.fasb.org/extlink&oid=120395691&loc=d3e24072-122690"
  },
  "r115": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "235",
   "URI": "http://asc.fasb.org/topic&trid=2122369"
  },
  "r116": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "23",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=124436220&loc=d3e21914-107793"
  },
  "r117": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "24",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=124436220&loc=d3e21930-107793"
  },
  "r118": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=124436220&loc=d3e21711-107793"
  },
  "r119": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "6",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=124436220&loc=d3e21728-107793"
  },
  "r12": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(22))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r120": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)(2)",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=124431687&loc=d3e22499-107794"
  },
  "r121": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)(3)",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=124431687&loc=d3e22499-107794"
  },
  "r122": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "11",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=124431687&loc=d3e22694-107794"
  },
  "r123": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "11",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=124431687&loc=d3e22694-107794"
  },
  "r124": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=124431687&loc=d3e22583-107794"
  },
  "r125": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=124431687&loc=d3e22595-107794"
  },
  "r126": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=124431687&loc=d3e22644-107794"
  },
  "r127": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=124431687&loc=d3e22644-107794"
  },
  "r128": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "8",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=124431687&loc=d3e22658-107794"
  },
  "r129": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "9",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=124431687&loc=d3e22663-107794"
  },
  "r13": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(27))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r130": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SAB Topic 11.M.Q2)",
   "Topic": "250",
   "URI": "http://asc.fasb.org/extlink&oid=122038215&loc=d3e31137-122693"
  },
  "r131": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "10",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "260",
   "URI": "http://asc.fasb.org/extlink&oid=125511455&loc=d3e1448-109256"
  },
  "r132": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "16",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "260",
   "URI": "http://asc.fasb.org/extlink&oid=125511455&loc=d3e1505-109256"
  },
  "r133": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "260",
   "URI": "http://asc.fasb.org/extlink&oid=125511455&loc=d3e1252-109256"
  },
  "r134": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "260",
   "URI": "http://asc.fasb.org/extlink&oid=125511455&loc=d3e1278-109256"
  },
  "r135": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "55",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "260",
   "URI": "http://asc.fasb.org/extlink&oid=125511455&loc=d3e2626-109256"
  },
  "r136": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "60B",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "260",
   "URI": "http://asc.fasb.org/extlink&oid=125511455&loc=SL5780133-109256"
  },
  "r137": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "60B",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(d)",
   "Topic": "260",
   "URI": "http://asc.fasb.org/extlink&oid=125511455&loc=SL5780133-109256"
  },
  "r138": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "260",
   "URI": "http://asc.fasb.org/extlink&oid=125511455&loc=d3e1337-109256"
  },
  "r139": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "260",
   "URI": "http://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257"
  },
  "r14": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(28))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r140": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "260",
   "URI": "http://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257"
  },
  "r141": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "260",
   "URI": "http://asc.fasb.org/extlink&oid=124432515&loc=d3e3630-109257"
  },
  "r142": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "260",
   "URI": "http://asc.fasb.org/extlink&oid=109243012&loc=SL65017193-207537"
  },
  "r143": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "15",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "10",
   "Topic": "260",
   "URI": "http://asc.fasb.org/extlink&oid=125512782&loc=d3e3842-109258"
  },
  "r144": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "52",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "10",
   "Topic": "260",
   "URI": "http://asc.fasb.org/extlink&oid=125512782&loc=d3e4984-109258"
  },
  "r145": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "260",
   "URI": "http://asc.fasb.org/topic&trid=2144383"
  },
  "r146": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "272",
   "URI": "http://asc.fasb.org/extlink&oid=125520817&loc=d3e70191-108054"
  },
  "r147": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "272",
   "URI": "http://asc.fasb.org/extlink&oid=125520817&loc=d3e70229-108054"
  },
  "r148": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "272",
   "URI": "http://asc.fasb.org/extlink&oid=6373374&loc=d3e70434-108055"
  },
  "r149": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "272",
   "URI": "http://asc.fasb.org/extlink&oid=6373374&loc=d3e70478-108055"
  },
  "r15": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(29))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r150": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "275",
   "URI": "http://asc.fasb.org/extlink&oid=99393423&loc=d3e5967-108592"
  },
  "r151": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "275",
   "URI": "http://asc.fasb.org/extlink&oid=99393423&loc=d3e5967-108592"
  },
  "r152": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "11",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "275",
   "URI": "http://asc.fasb.org/extlink&oid=99393423&loc=d3e6161-108592"
  },
  "r153": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "12",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "275",
   "URI": "http://asc.fasb.org/extlink&oid=99393423&loc=d3e6191-108592"
  },
  "r154": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "275",
   "URI": "http://asc.fasb.org/extlink&oid=99393423&loc=d3e6061-108592"
  },
  "r155": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "8",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "275",
   "URI": "http://asc.fasb.org/extlink&oid=99393423&loc=d3e6132-108592"
  },
  "r156": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "9",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "275",
   "URI": "http://asc.fasb.org/extlink&oid=99393423&loc=d3e6143-108592"
  },
  "r157": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "18",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8672-108599"
  },
  "r158": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "22",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8736-108599"
  },
  "r159": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "22",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8736-108599"
  },
  "r16": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(3))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r160": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "22",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(e)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8736-108599"
  },
  "r161": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "22",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(g)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8736-108599"
  },
  "r162": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "22",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(h)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8736-108599"
  },
  "r163": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "22",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8736-108599"
  },
  "r164": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "25",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8813-108599"
  },
  "r165": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "30",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8906-108599"
  },
  "r166": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "30",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8906-108599"
  },
  "r167": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "30",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8906-108599"
  },
  "r168": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "31",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8924-108599"
  },
  "r169": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "32",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8933-108599"
  },
  "r17": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(30)(a)(1))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r170": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "32",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8933-108599"
  },
  "r171": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "32",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8933-108599"
  },
  "r172": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "32",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(d)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8933-108599"
  },
  "r173": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "32",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(f)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e8933-108599"
  },
  "r174": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "40",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e9031-108599"
  },
  "r175": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "41",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e9038-108599"
  },
  "r176": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "41",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e9038-108599"
  },
  "r177": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "42",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "280",
   "URI": "http://asc.fasb.org/extlink&oid=123359005&loc=d3e9054-108599"
  },
  "r178": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "310",
   "URI": "http://asc.fasb.org/extlink&oid=124259787&loc=d3e4428-111522"
  },
  "r179": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "9",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "310",
   "URI": "http://asc.fasb.org/extlink&oid=124259787&loc=d3e4531-111522"
  },
  "r18": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(30)(a)(3))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r180": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SAB Topic 4.E)",
   "Topic": "310",
   "URI": "http://asc.fasb.org/extlink&oid=122038336&loc=d3e74512-122707"
  },
  "r181": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=124260329&loc=d3e26610-111562"
  },
  "r182": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "11",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=124260329&loc=d3e26853-111562"
  },
  "r183": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=124260329&loc=d3e26626-111562"
  },
  "r184": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=SL6283291-111563"
  },
  "r185": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=d3e27161-111563"
  },
  "r186": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(aa)",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=d3e27161-111563"
  },
  "r187": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=d3e27161-111563"
  },
  "r188": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=d3e27161-111563"
  },
  "r189": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(d)",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=d3e27161-111563"
  },
  "r19": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(30)(a)(4))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r190": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=d3e27161-111563"
  },
  "r191": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=d3e27198-111563"
  },
  "r192": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=d3e27198-111563"
  },
  "r193": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=d3e27232-111563"
  },
  "r194": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5A",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=SL120269820-111563"
  },
  "r195": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "6",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=d3e27290-111563"
  },
  "r196": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=d3e27337-111563"
  },
  "r197": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "8",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=d3e27340-111563"
  },
  "r198": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "9",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=d3e27357-111563"
  },
  "r199": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "9",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)-(d)",
   "Topic": "320",
   "URI": "http://asc.fasb.org/extlink&oid=123581744&loc=d3e27357-111563"
  },
  "r2": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=124098289&loc=d3e6676-107765"
  },
  "r20": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(30))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r200": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "320",
   "URI": "http://asc.fasb.org/topic&trid=2196928"
  },
  "r201": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "321",
   "URI": "http://asc.fasb.org/extlink&oid=123583765&loc=SL75117539-209714"
  },
  "r202": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "321",
   "URI": "http://asc.fasb.org/extlink&oid=123583765&loc=SL75117539-209714"
  },
  "r203": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "321",
   "URI": "http://asc.fasb.org/extlink&oid=123583765&loc=SL75117539-209714"
  },
  "r204": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "321",
   "URI": "http://asc.fasb.org/extlink&oid=123583765&loc=SL75117546-209714"
  },
  "r205": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "25",
   "SubTopic": "10",
   "Topic": "323",
   "URI": "http://asc.fasb.org/extlink&oid=125513658&loc=d3e32014-111567"
  },
  "r206": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "323",
   "URI": "http://asc.fasb.org/extlink&oid=109237563&loc=d3e33749-111570"
  },
  "r207": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)(1)",
   "Topic": "323",
   "URI": "http://asc.fasb.org/extlink&oid=114001798&loc=d3e33918-111571"
  },
  "r208": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)(3)",
   "Topic": "323",
   "URI": "http://asc.fasb.org/extlink&oid=114001798&loc=d3e33918-111571"
  },
  "r209": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "323",
   "URI": "http://asc.fasb.org/extlink&oid=114001798&loc=d3e33918-111571"
  },
  "r21": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(31))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r210": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "323",
   "URI": "http://asc.fasb.org/extlink&oid=114001798&loc=d3e33918-111571"
  },
  "r211": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "10",
   "Subparagraph": "(d)",
   "Topic": "326",
   "URI": "http://asc.fasb.org/extlink&oid=122640432&loc=SL121648383-210437"
  },
  "r212": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "11",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "326",
   "URI": "http://asc.fasb.org/extlink&oid=124255953&loc=SL82919244-210447"
  },
  "r213": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "326",
   "URI": "http://asc.fasb.org/extlink&oid=124255953&loc=SL82919249-210447"
  },
  "r214": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "14",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "326",
   "URI": "http://asc.fasb.org/extlink&oid=124255953&loc=SL82919253-210447"
  },
  "r215": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "16",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "326",
   "URI": "http://asc.fasb.org/extlink&oid=124255953&loc=SL82919258-210447"
  },
  "r216": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "326",
   "URI": "http://asc.fasb.org/extlink&oid=124255953&loc=SL82919230-210447"
  },
  "r217": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "30",
   "Topic": "326",
   "URI": "http://asc.fasb.org/extlink&oid=124258926&loc=SL82898722-210454"
  },
  "r218": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Topic": "326",
   "URI": "http://asc.fasb.org/extlink&oid=124269663&loc=SL82922888-210455"
  },
  "r219": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Topic": "326",
   "URI": "http://asc.fasb.org/extlink&oid=124269663&loc=SL82922895-210455"
  },
  "r22": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(32))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r220": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "9",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Topic": "326",
   "URI": "http://asc.fasb.org/extlink&oid=124269663&loc=SL82922900-210455"
  },
  "r221": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "8",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "30",
   "Topic": "326",
   "URI": "http://asc.fasb.org/extlink&oid=121590138&loc=SL82922954-210456"
  },
  "r222": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SAB Topic 5.BB)",
   "Topic": "330",
   "URI": "http://asc.fasb.org/extlink&oid=27011343&loc=d3e100047-122729"
  },
  "r223": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "330",
   "URI": "http://asc.fasb.org/topic&trid=2126998"
  },
  "r224": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "20",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=99380562&loc=d3e13770-109266"
  },
  "r225": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "20",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=120320667&loc=SL49117168-202975"
  },
  "r226": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(f)",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=121556970&loc=d3e13816-109267"
  },
  "r227": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=121556970&loc=d3e13816-109267"
  },
  "r228": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=121556970&loc=d3e13854-109267"
  },
  "r229": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "30",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=6388964&loc=d3e16212-109274"
  },
  "r23": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(6)(a)(1))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r230": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "30",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=6388964&loc=d3e16225-109274"
  },
  "r231": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(a)",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=66006027&loc=d3e16265-109275"
  },
  "r232": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(b)",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=66006027&loc=d3e16265-109275"
  },
  "r233": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(c)",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=66006027&loc=d3e16265-109275"
  },
  "r234": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(d)",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=66006027&loc=d3e16265-109275"
  },
  "r235": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "((a)(1),(b))",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275"
  },
  "r236": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(a)",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275"
  },
  "r237": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(a)(1)",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275"
  },
  "r238": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(a)(2)",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275"
  },
  "r239": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(a)(3)",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275"
  },
  "r24": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(6)(a)(3))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r240": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(b)",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275"
  },
  "r241": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(d)",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275"
  },
  "r242": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(b),(d)",
   "Topic": "350",
   "URI": "http://asc.fasb.org/extlink&oid=66006027&loc=d3e16373-109275"
  },
  "r243": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "350",
   "URI": "http://asc.fasb.org/topic&trid=2144416"
  },
  "r244": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "360",
   "URI": "http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229"
  },
  "r245": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "360",
   "URI": "http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229"
  },
  "r246": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(d)",
   "Topic": "360",
   "URI": "http://asc.fasb.org/extlink&oid=109226691&loc=d3e2941-110230"
  },
  "r247": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "420",
   "URI": "http://asc.fasb.org/extlink&oid=6394359&loc=d3e17939-110869"
  },
  "r248": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "440",
   "URI": "http://asc.fasb.org/extlink&oid=123406679&loc=d3e25336-109308"
  },
  "r249": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "440",
   "URI": "http://asc.fasb.org/extlink&oid=123406679&loc=d3e25336-109308"
  },
  "r25": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(6)(a)(4))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r250": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "440",
   "URI": "http://asc.fasb.org/topic&trid=2144648"
  },
  "r251": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "450",
   "URI": "http://asc.fasb.org/extlink&oid=121557415&loc=d3e14326-108349"
  },
  "r252": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "10",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "450",
   "URI": "http://asc.fasb.org/extlink&oid=121557415&loc=d3e14615-108349"
  },
  "r253": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "450",
   "URI": "http://asc.fasb.org/extlink&oid=121557415&loc=d3e14394-108349"
  },
  "r254": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(a)",
   "Topic": "450",
   "URI": "http://asc.fasb.org/extlink&oid=121557415&loc=d3e14435-108349"
  },
  "r255": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "450",
   "URI": "http://asc.fasb.org/extlink&oid=121557415&loc=d3e14435-108349"
  },
  "r256": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "450",
   "URI": "http://asc.fasb.org/extlink&oid=121557415&loc=d3e14453-108349"
  },
  "r257": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "6",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "450",
   "URI": "http://asc.fasb.org/extlink&oid=121557415&loc=d3e14472-108349"
  },
  "r258": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "9",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "450",
   "URI": "http://asc.fasb.org/extlink&oid=121557415&loc=d3e14557-108349"
  },
  "r259": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "450",
   "URI": "http://asc.fasb.org/topic&trid=2127136"
  },
  "r26": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(6)(a))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r260": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "460",
   "URI": "http://asc.fasb.org/extlink&oid=124440162&loc=d3e12021-110248"
  },
  "r261": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "460",
   "URI": "http://asc.fasb.org/extlink&oid=124440162&loc=d3e12053-110248"
  },
  "r262": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123465755&loc=SL6230698-112601"
  },
  "r263": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.13-01(a)(4)(i))",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=124359900&loc=SL124442526-122756"
  },
  "r264": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.13-01(a)(4)(ii))",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=124359900&loc=SL124442526-122756"
  },
  "r265": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.13-01(a)(4)(iii)(A))",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=124359900&loc=SL124442526-122756"
  },
  "r266": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.13-01(a)(4)(iii))",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=124359900&loc=SL124442526-122756"
  },
  "r267": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.13-01(a)(4)(iv))",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=124359900&loc=SL124442526-122756"
  },
  "r268": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.13-01(a)(5))",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=124359900&loc=SL124442526-122756"
  },
  "r269": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.13-02(a)(4)(i))",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=124359900&loc=SL124442552-122756"
  },
  "r27": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(6)(b))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r270": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.13-02(a)(4)(iii)(A))",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=124359900&loc=SL124442552-122756"
  },
  "r271": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.13-02(a)(4)(iii)(B))",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=124359900&loc=SL124442552-122756"
  },
  "r272": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.13-02(a)(4)(iv))",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=124359900&loc=SL124442552-122756"
  },
  "r273": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.13-02(a)(5))",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=124359900&loc=SL124442552-122756"
  },
  "r274": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(a)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495323-112611"
  },
  "r275": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495323-112611"
  },
  "r276": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(c)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495323-112611"
  },
  "r277": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(d)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495323-112611"
  },
  "r278": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(e)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495323-112611"
  },
  "r279": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(f)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495323-112611"
  },
  "r28": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(6)(c))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r280": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(g)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495323-112611"
  },
  "r281": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(h)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495323-112611"
  },
  "r282": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(i)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495323-112611"
  },
  "r283": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495323-112611"
  },
  "r284": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1C",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(a)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495334-112611"
  },
  "r285": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1C",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495334-112611"
  },
  "r286": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1C",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(c)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495334-112611"
  },
  "r287": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1D",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(a)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495340-112611"
  },
  "r288": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1D",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495340-112611"
  },
  "r289": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1D",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(c)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495340-112611"
  },
  "r29": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.1)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r290": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1E",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(a)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495348-112611"
  },
  "r291": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1E",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495348-112611"
  },
  "r292": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1E",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(c)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495348-112611"
  },
  "r293": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1E",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(d)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495348-112611"
  },
  "r294": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1F",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(a)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495355-112611"
  },
  "r295": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1F",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495355-112611"
  },
  "r296": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1F",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)(1)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495355-112611"
  },
  "r297": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1F",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)(2)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495355-112611"
  },
  "r298": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1I",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(a)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495371-112611"
  },
  "r299": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1I",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495371-112611"
  },
  "r3": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=124098289&loc=d3e6676-107765"
  },
  "r30": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.12)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r300": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1I",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(c)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495371-112611"
  },
  "r301": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1I",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(d)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466505&loc=SL123495371-112611"
  },
  "r302": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)(1)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466204&loc=SL6031897-161870"
  },
  "r303": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)(2)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466204&loc=SL6031897-161870"
  },
  "r304": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)(3)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466204&loc=SL6031897-161870"
  },
  "r305": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "6",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(a)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466204&loc=SL6036836-161870"
  },
  "r306": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "6",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466204&loc=SL6036836-161870"
  },
  "r307": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "69B",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "20",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466577&loc=SL123495735-112612"
  },
  "r308": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "69C",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "20",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466577&loc=SL123495737-112612"
  },
  "r309": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "69E",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "20",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466577&loc=SL123495743-112612"
  },
  "r31": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.13(a))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r310": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "69F",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "20",
   "Topic": "470",
   "URI": "http://asc.fasb.org/extlink&oid=123466577&loc=SL123495745-112612"
  },
  "r311": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "470",
   "URI": "http://asc.fasb.org/topic&trid=2208564"
  },
  "r312": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(CFRR 211.02)",
   "Topic": "480",
   "URI": "http://asc.fasb.org/extlink&oid=122040564&loc=d3e177068-122764"
  },
  "r313": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=65888546&loc=d3e21300-112643"
  },
  "r314": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "10",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=d3e21553-112644"
  },
  "r315": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496158-112644"
  },
  "r316": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496158-112644"
  },
  "r317": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(d)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496158-112644"
  },
  "r318": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(e)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496158-112644"
  },
  "r319": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(g)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496158-112644"
  },
  "r32": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.14)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r320": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(h)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496158-112644"
  },
  "r321": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(i)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496158-112644"
  },
  "r322": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496158-112644"
  },
  "r323": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "14",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496171-112644"
  },
  "r324": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "14",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496171-112644"
  },
  "r325": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "14",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496171-112644"
  },
  "r326": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "16",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496180-112644"
  },
  "r327": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "18",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496189-112644"
  },
  "r328": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "18",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496189-112644"
  },
  "r329": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "18",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496189-112644"
  },
  "r33": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.17)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r330": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "18",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(d)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=SL123496189-112644"
  },
  "r331": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=d3e21463-112644"
  },
  "r332": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=d3e21475-112644"
  },
  "r333": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=d3e21484-112644"
  },
  "r334": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=d3e21488-112644"
  },
  "r335": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "6",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=d3e21506-112644"
  },
  "r336": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=d3e21521-112644"
  },
  "r337": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "8",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=123467817&loc=d3e21538-112644"
  },
  "r338": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.3-04)",
   "Topic": "505",
   "URI": "http://asc.fasb.org/extlink&oid=120397183&loc=d3e187085-122770"
  },
  "r339": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "505",
   "URI": "http://asc.fasb.org/topic&trid=2208762"
  },
  "r34": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.19(a))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r340": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "10",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "606",
   "URI": "http://asc.fasb.org/extlink&oid=123351226&loc=SL49130551-203045"
  },
  "r341": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "12",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "606",
   "URI": "http://asc.fasb.org/extlink&oid=123351226&loc=SL49130554-203045"
  },
  "r342": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "12",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "606",
   "URI": "http://asc.fasb.org/extlink&oid=123351226&loc=SL49130554-203045"
  },
  "r343": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "12",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "606",
   "URI": "http://asc.fasb.org/extlink&oid=123351226&loc=SL49130554-203045"
  },
  "r344": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "12",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(d)",
   "Topic": "606",
   "URI": "http://asc.fasb.org/extlink&oid=123351226&loc=SL49130554-203045"
  },
  "r345": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "12",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(e)",
   "Topic": "606",
   "URI": "http://asc.fasb.org/extlink&oid=123351226&loc=SL49130554-203045"
  },
  "r346": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)(2)",
   "Topic": "606",
   "URI": "http://asc.fasb.org/extlink&oid=123351226&loc=SL49130556-203045"
  },
  "r347": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "15",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "606",
   "URI": "http://asc.fasb.org/extlink&oid=123351226&loc=SL49130558-203045"
  },
  "r348": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "606",
   "URI": "http://asc.fasb.org/extlink&oid=123351226&loc=SL49130543-203045"
  },
  "r349": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "606",
   "URI": "http://asc.fasb.org/extlink&oid=123351226&loc=SL49130545-203045"
  },
  "r35": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.19,20)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r350": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "9",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "606",
   "URI": "http://asc.fasb.org/extlink&oid=123351226&loc=SL49130550-203045"
  },
  "r351": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "91",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "606",
   "URI": "http://asc.fasb.org/extlink&oid=123410239&loc=SL49130690-203046-203046"
  },
  "r352": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "91",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "606",
   "URI": "http://asc.fasb.org/extlink&oid=123410239&loc=SL49130690-203046-203046"
  },
  "r353": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "606",
   "URI": "http://asc.fasb.org/topic&trid=49130388"
  },
  "r354": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(d)(i)",
   "Topic": "715",
   "URI": "http://asc.fasb.org/extlink&oid=123447040&loc=d3e1928-114920"
  },
  "r355": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(d)(ii)",
   "Topic": "715",
   "URI": "http://asc.fasb.org/extlink&oid=123447040&loc=d3e1928-114920"
  },
  "r356": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(d)(iv)(01)",
   "Topic": "715",
   "URI": "http://asc.fasb.org/extlink&oid=123447040&loc=d3e1928-114920"
  },
  "r357": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(d)(iv)(02)",
   "Topic": "715",
   "URI": "http://asc.fasb.org/extlink&oid=123447040&loc=d3e1928-114920"
  },
  "r358": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(d)(iv)(02)(A)",
   "Topic": "715",
   "URI": "http://asc.fasb.org/extlink&oid=123447040&loc=d3e1928-114920"
  },
  "r359": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(d)(iv)(02)(B)",
   "Topic": "715",
   "URI": "http://asc.fasb.org/extlink&oid=123447040&loc=d3e1928-114920"
  },
  "r36": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.19,20,22)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r360": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(d)(iv)(02)(C)",
   "Topic": "715",
   "URI": "http://asc.fasb.org/extlink&oid=123447040&loc=d3e1928-114920"
  },
  "r361": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(d)(iv)(03)",
   "Topic": "715",
   "URI": "http://asc.fasb.org/extlink&oid=123447040&loc=d3e1928-114920"
  },
  "r362": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "17",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "20",
   "Topic": "715",
   "URI": "http://asc.fasb.org/extlink&oid=123450688&loc=d3e4179-114921"
  },
  "r363": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "11",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "80",
   "Subparagraph": "(a)",
   "Topic": "715",
   "URI": "http://asc.fasb.org/extlink&oid=65877416&loc=SL14450702-114947"
  },
  "r364": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "80",
   "Subparagraph": "(d)",
   "Topic": "715",
   "URI": "http://asc.fasb.org/extlink&oid=65877416&loc=SL14450657-114947"
  },
  "r365": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "80",
   "Subparagraph": "(f)(3)",
   "Topic": "715",
   "URI": "http://asc.fasb.org/extlink&oid=65877416&loc=SL14450657-114947"
  },
  "r366": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "6",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "80",
   "Subparagraph": "(a)",
   "Topic": "715",
   "URI": "http://asc.fasb.org/extlink&oid=65877416&loc=SL14450673-114947"
  },
  "r367": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "8",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "80",
   "Topic": "715",
   "URI": "http://asc.fasb.org/extlink&oid=35742348&loc=SL14450788-114948"
  },
  "r368": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "35",
   "SubTopic": "10",
   "Topic": "718",
   "URI": "http://asc.fasb.org/extlink&oid=123468992&loc=d3e4534-113899"
  },
  "r369": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "718",
   "URI": "http://asc.fasb.org/extlink&oid=120381028&loc=d3e5047-113901"
  },
  "r37": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.20)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r370": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "718",
   "URI": "http://asc.fasb.org/extlink&oid=120381028&loc=d3e5047-113901"
  },
  "r371": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(d)(1)",
   "Topic": "718",
   "URI": "http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901"
  },
  "r372": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "15",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "10",
   "Subparagraph": "(e)",
   "Topic": "718",
   "URI": "http://asc.fasb.org/extlink&oid=121322162&loc=SL121327923-165333"
  },
  "r373": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "15",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "10",
   "Subparagraph": "(f)(1)",
   "Topic": "718",
   "URI": "http://asc.fasb.org/extlink&oid=121322162&loc=SL121327923-165333"
  },
  "r374": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "15",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "10",
   "Subparagraph": "(f)(2)",
   "Topic": "718",
   "URI": "http://asc.fasb.org/extlink&oid=121322162&loc=SL121327923-165333"
  },
  "r375": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "15",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "10",
   "Subparagraph": "(g)(2)",
   "Topic": "718",
   "URI": "http://asc.fasb.org/extlink&oid=121322162&loc=SL121327923-165333"
  },
  "r376": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "12",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "20",
   "Topic": "718",
   "URI": "http://asc.fasb.org/extlink&oid=122142933&loc=d3e11149-113907"
  },
  "r377": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "20",
   "Topic": "718",
   "URI": "http://asc.fasb.org/extlink&oid=122142933&loc=d3e11178-113907"
  },
  "r378": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "730",
   "URI": "http://asc.fasb.org/extlink&oid=6420194&loc=d3e21568-108373"
  },
  "r379": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)",
   "Topic": "730",
   "URI": "http://asc.fasb.org/extlink&oid=6420387&loc=d3e23199-108380"
  },
  "r38": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.21)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r380": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "730",
   "URI": "http://asc.fasb.org/extlink&oid=6420387&loc=d3e23221-108380"
  },
  "r381": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "10",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "740",
   "URI": "http://asc.fasb.org/extlink&oid=121826272&loc=d3e32672-109319"
  },
  "r382": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "12",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "740",
   "URI": "http://asc.fasb.org/extlink&oid=121826272&loc=d3e32687-109319"
  },
  "r383": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "14",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "740",
   "URI": "http://asc.fasb.org/extlink&oid=121826272&loc=d3e32705-109319"
  },
  "r384": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "15A",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)(2)",
   "Topic": "740",
   "URI": "http://asc.fasb.org/extlink&oid=121826272&loc=SL6600010-109319"
  },
  "r385": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "17",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "740",
   "URI": "http://asc.fasb.org/extlink&oid=121826272&loc=d3e32809-109319"
  },
  "r386": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "21",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "740",
   "URI": "http://asc.fasb.org/extlink&oid=121826272&loc=d3e32857-109319"
  },
  "r387": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "8",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "10",
   "Subparagraph": "(d)(2)",
   "Topic": "740",
   "URI": "http://asc.fasb.org/extlink&oid=123459177&loc=SL121830611-158277"
  },
  "r388": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "8",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "10",
   "Subparagraph": "(d)(3)",
   "Topic": "740",
   "URI": "http://asc.fasb.org/extlink&oid=123459177&loc=SL121830611-158277"
  },
  "r389": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SAB TOPIC 6.I.5.Q1)",
   "Topic": "740",
   "URI": "http://asc.fasb.org/extlink&oid=122134291&loc=d3e330036-122817"
  },
  "r39": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.22(a)(1))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r390": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SAB TOPIC 6.I.7)",
   "Topic": "740",
   "URI": "http://asc.fasb.org/extlink&oid=122134291&loc=d3e330036-122817"
  },
  "r391": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SAB Topic 11.C)",
   "Topic": "740",
   "URI": "http://asc.fasb.org/extlink&oid=122134291&loc=d3e330215-122817"
  },
  "r392": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "20",
   "Subparagraph": "(a)",
   "Topic": "740",
   "URI": "http://asc.fasb.org/extlink&oid=123586238&loc=d3e38679-109324"
  },
  "r393": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "270",
   "Topic": "740",
   "URI": "http://asc.fasb.org/extlink&oid=6424409&loc=d3e44925-109338"
  },
  "r394": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(a)",
   "Topic": "740",
   "URI": "http://asc.fasb.org/extlink&oid=6424122&loc=d3e41874-109331"
  },
  "r395": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "740",
   "URI": "http://asc.fasb.org/topic&trid=2144680"
  },
  "r396": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "805",
   "URI": "http://asc.fasb.org/extlink&oid=79982066&loc=d3e1392-128463"
  },
  "r397": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "805",
   "URI": "http://asc.fasb.org/extlink&oid=79982066&loc=d3e1486-128463"
  },
  "r398": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(c)",
   "Topic": "805",
   "URI": "http://asc.fasb.org/extlink&oid=123413009&loc=d3e4845-128472"
  },
  "r399": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "20",
   "Topic": "805",
   "URI": "http://asc.fasb.org/extlink&oid=123410050&loc=d3e5227-128473"
  },
  "r4": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=124098289&loc=d3e6676-107765"
  },
  "r40": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.22)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r400": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "31",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "20",
   "Subparagraph": "(a)",
   "Topic": "805",
   "URI": "http://asc.fasb.org/extlink&oid=123410050&loc=d3e5419-128473"
  },
  "r401": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "38",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "20",
   "Topic": "805",
   "URI": "http://asc.fasb.org/extlink&oid=123410050&loc=d3e5504-128473"
  },
  "r402": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "6",
   "Publisher": "FASB",
   "Section": "25",
   "SubTopic": "30",
   "Topic": "805",
   "URI": "http://asc.fasb.org/extlink&oid=6911189&loc=d3e6408-128476"
  },
  "r403": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "35",
   "SubTopic": "30",
   "Subparagraph": "(b)",
   "Topic": "805",
   "URI": "http://asc.fasb.org/extlink&oid=116859824&loc=d3e6819-128478"
  },
  "r404": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(b)(1)",
   "Topic": "805",
   "URI": "http://asc.fasb.org/extlink&oid=120321790&loc=d3e6927-128479"
  },
  "r405": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(c)(1)",
   "Topic": "805",
   "URI": "http://asc.fasb.org/extlink&oid=120321790&loc=d3e6927-128479"
  },
  "r406": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(c)(3)",
   "Topic": "805",
   "URI": "http://asc.fasb.org/extlink&oid=120321790&loc=d3e6927-128479"
  },
  "r407": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "805",
   "URI": "http://asc.fasb.org/topic&trid=2303972"
  },
  "r408": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "808",
   "URI": "http://asc.fasb.org/extlink&oid=6931272&loc=SL5834143-161434"
  },
  "r409": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "808",
   "URI": "http://asc.fasb.org/extlink&oid=6931272&loc=SL5834143-161434"
  },
  "r41": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.24)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r410": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "808",
   "URI": "http://asc.fasb.org/extlink&oid=6931272&loc=SL5834143-161434"
  },
  "r411": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "808",
   "URI": "http://asc.fasb.org/topic&trid=5833765"
  },
  "r412": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "19",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "810",
   "URI": "http://asc.fasb.org/extlink&oid=123454820&loc=SL4569616-111683"
  },
  "r413": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "20",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "810",
   "URI": "http://asc.fasb.org/extlink&oid=123454820&loc=SL4569643-111683"
  },
  "r414": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "25",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "810",
   "URI": "http://asc.fasb.org/extlink&oid=116870748&loc=SL6758485-165988"
  },
  "r415": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "25",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "810",
   "URI": "http://asc.fasb.org/extlink&oid=116870748&loc=SL6758485-165988"
  },
  "r416": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "810",
   "URI": "http://asc.fasb.org/extlink&oid=109239629&loc=d3e5614-111684"
  },
  "r417": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)(3)",
   "Topic": "810",
   "URI": "http://asc.fasb.org/extlink&oid=109239629&loc=SL4573702-111684"
  },
  "r418": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c),(3)",
   "Topic": "810",
   "URI": "http://asc.fasb.org/extlink&oid=109239629&loc=SL4573702-111684"
  },
  "r419": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(bb)",
   "Topic": "810",
   "URI": "http://asc.fasb.org/extlink&oid=123419778&loc=d3e5710-111685"
  },
  "r42": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.25)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r420": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "810",
   "URI": "http://asc.fasb.org/extlink&oid=123419778&loc=d3e5710-111685"
  },
  "r421": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5579240-113959"
  },
  "r422": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(d)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5579245-113959"
  },
  "r423": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5579245-113959"
  },
  "r424": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5580258-113959"
  },
  "r425": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)(1)(ii)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=d3e41620-113959"
  },
  "r426": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=d3e41620-113959"
  },
  "r427": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=d3e41638-113959"
  },
  "r428": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4A",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5618551-113959"
  },
  "r429": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4A",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5618551-113959"
  },
  "r43": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.28,29)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r430": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4A",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5618551-113959"
  },
  "r431": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a),(c)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5624163-113959"
  },
  "r432": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)(1)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5624163-113959"
  },
  "r433": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(d)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5624163-113959"
  },
  "r434": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4B",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5624163-113959"
  },
  "r435": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4C",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5624171-113959"
  },
  "r436": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4C",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5624171-113959"
  },
  "r437": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4C",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5624171-113959"
  },
  "r438": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4D",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5624177-113959"
  },
  "r439": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4D",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)(1)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5624177-113959"
  },
  "r44": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.29-31)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r440": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4D",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)(2)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5624177-113959"
  },
  "r441": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4D",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5624177-113959"
  },
  "r442": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4E",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL5624181-113959"
  },
  "r443": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4EE",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL109999712-113959"
  },
  "r444": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4EE",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL109999712-113959"
  },
  "r445": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4EE",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(d)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=SL109999712-113959"
  },
  "r446": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=d3e41641-113959"
  },
  "r447": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "8",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=125515794&loc=d3e41678-113959"
  },
  "r448": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "182",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "10",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=123421605&loc=SL5629052-113961"
  },
  "r449": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "25",
   "Subparagraph": "(a)(1)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=121577467&loc=d3e76258-113986"
  },
  "r45": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.6(a))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r450": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "25",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=121577467&loc=d3e76258-113986"
  },
  "r451": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(c)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=121549185&loc=d3e80748-113994"
  },
  "r452": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(d)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=121549185&loc=d3e80748-113994"
  },
  "r453": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "40",
   "Subparagraph": "(f)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=123477628&loc=d3e90205-114008"
  },
  "r454": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "40",
   "Subparagraph": "(b)(1)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=123482062&loc=SL123482106-238011"
  },
  "r455": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "40",
   "Subparagraph": "(d)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=123482062&loc=SL123482106-238011"
  },
  "r456": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "40",
   "Subparagraph": "(e)(3)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=123482062&loc=SL123482106-238011"
  },
  "r457": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "40",
   "Subparagraph": "(e)(4)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=123482062&loc=SL123482106-238011"
  },
  "r458": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "40",
   "Subparagraph": "(f)",
   "Topic": "815",
   "URI": "http://asc.fasb.org/extlink&oid=123482062&loc=SL123482106-238011"
  },
  "r459": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "815",
   "URI": "http://asc.fasb.org/topic&trid=2229140"
  },
  "r46": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.8)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r460": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "54B",
   "Publisher": "FASB",
   "Section": "35",
   "SubTopic": "10",
   "Topic": "820",
   "URI": "http://asc.fasb.org/extlink&oid=122636397&loc=SL7495116-110257"
  },
  "r461": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "820",
   "URI": "http://asc.fasb.org/extlink&oid=123874694&loc=d3e19207-110258"
  },
  "r462": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "820",
   "URI": "http://asc.fasb.org/extlink&oid=123874694&loc=d3e19207-110258"
  },
  "r463": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(bb)",
   "Topic": "820",
   "URI": "http://asc.fasb.org/extlink&oid=123874694&loc=d3e19207-110258"
  },
  "r464": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "820",
   "URI": "http://asc.fasb.org/extlink&oid=123874694&loc=d3e19207-110258"
  },
  "r465": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "820",
   "URI": "http://asc.fasb.org/extlink&oid=123874694&loc=d3e19207-110258"
  },
  "r466": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "820",
   "URI": "http://asc.fasb.org/extlink&oid=123874694&loc=d3e19279-110258"
  },
  "r467": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "6A",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "820",
   "URI": "http://asc.fasb.org/extlink&oid=123874694&loc=SL6742756-110258"
  },
  "r468": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "6A",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "820",
   "URI": "http://asc.fasb.org/extlink&oid=123874694&loc=SL6742756-110258"
  },
  "r469": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "825",
   "URI": "http://asc.fasb.org/extlink&oid=123594786&loc=SL75136599-209740"
  },
  "r47": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02.9)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r470": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "28",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(f)",
   "Topic": "825",
   "URI": "http://asc.fasb.org/extlink&oid=123596393&loc=d3e14064-108612"
  },
  "r471": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "230",
   "Topic": "830",
   "URI": "http://asc.fasb.org/extlink&oid=123444420&loc=d3e33268-110906"
  },
  "r472": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "17",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "30",
   "Topic": "830",
   "URI": "http://asc.fasb.org/extlink&oid=118261656&loc=d3e32136-110900"
  },
  "r473": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "20",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "30",
   "Subparagraph": "(a)",
   "Topic": "830",
   "URI": "http://asc.fasb.org/extlink&oid=118261656&loc=d3e32211-110900"
  },
  "r474": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "20",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "30",
   "Subparagraph": "(b)",
   "Topic": "830",
   "URI": "http://asc.fasb.org/extlink&oid=118261656&loc=d3e32211-110900"
  },
  "r475": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "20",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "30",
   "Subparagraph": "(c)",
   "Topic": "830",
   "URI": "http://asc.fasb.org/extlink&oid=118261656&loc=d3e32211-110900"
  },
  "r476": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "20",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "30",
   "Subparagraph": "(d)",
   "Topic": "830",
   "URI": "http://asc.fasb.org/extlink&oid=118261656&loc=d3e32211-110900"
  },
  "r477": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "20",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "30",
   "Topic": "830",
   "URI": "http://asc.fasb.org/extlink&oid=118261656&loc=d3e32211-110900"
  },
  "r478": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Topic": "830",
   "URI": "http://asc.fasb.org/extlink&oid=6450520&loc=d3e32583-110901"
  },
  "r479": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Topic": "830",
   "URI": "http://asc.fasb.org/extlink&oid=6450520&loc=d3e32618-110901"
  },
  "r48": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(a)",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=51824906&loc=SL20225862-175312"
  },
  "r480": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "30",
   "Topic": "835",
   "URI": "http://asc.fasb.org/extlink&oid=124435984&loc=d3e28541-108399"
  },
  "r481": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "30",
   "Topic": "835",
   "URI": "http://asc.fasb.org/extlink&oid=124435984&loc=d3e28551-108399"
  },
  "r482": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "30",
   "Topic": "835",
   "URI": "http://asc.fasb.org/extlink&oid=124435984&loc=d3e28555-108399"
  },
  "r483": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Topic": "835",
   "URI": "http://asc.fasb.org/extlink&oid=124429444&loc=SL124452920-239629"
  },
  "r484": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "8",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "30",
   "Topic": "835",
   "URI": "http://asc.fasb.org/extlink&oid=114775985&loc=d3e28878-108400"
  },
  "r485": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "852",
   "URI": "http://asc.fasb.org/extlink&oid=124433192&loc=SL2890621-112765"
  },
  "r486": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "852",
   "URI": "http://asc.fasb.org/extlink&oid=124433192&loc=SL2890621-112765"
  },
  "r487": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "10",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "10",
   "Topic": "852",
   "URI": "http://asc.fasb.org/extlink&oid=84165509&loc=d3e56426-112766"
  },
  "r488": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "855",
   "URI": "http://asc.fasb.org/extlink&oid=6842918&loc=SL6314017-165662"
  },
  "r489": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "855",
   "URI": "http://asc.fasb.org/extlink&oid=6842918&loc=SL6314017-165662"
  },
  "r49": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "22",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "20",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=99393222&loc=SL20226052-175313"
  },
  "r490": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "855",
   "URI": "http://asc.fasb.org/extlink&oid=6842918&loc=SL6314020-165662"
  },
  "r491": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "Topic": "855",
   "URI": "http://asc.fasb.org/topic&trid=2122774"
  },
  "r492": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)(2)(i)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=121570589&loc=d3e107207-111719"
  },
  "r493": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)(2)(ii)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=121570589&loc=d3e107207-111719"
  },
  "r494": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)(3)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=121570589&loc=d3e107207-111719"
  },
  "r495": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(bb)(1)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=121570589&loc=d3e107207-111719"
  },
  "r496": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(bb)(2)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=121570589&loc=d3e107207-111719"
  },
  "r497": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(bb)(3)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=121570589&loc=d3e107207-111719"
  },
  "r498": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(c)(1)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=121570589&loc=d3e107207-111719"
  },
  "r499": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(c)(2)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=121570589&loc=d3e107207-111719"
  },
  "r5": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=124098289&loc=d3e6676-107765"
  },
  "r50": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "20",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=99393222&loc=SL20226000-175313"
  },
  "r500": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(c)(3)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=121570589&loc=d3e107207-111719"
  },
  "r501": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)(1)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=121570589&loc=d3e107314-111719"
  },
  "r502": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)(2)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=121570589&loc=d3e107314-111719"
  },
  "r503": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(b)(3)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=121570589&loc=d3e107314-111719"
  },
  "r504": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(c)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=121570589&loc=d3e107314-111719"
  },
  "r505": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4D",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Subparagraph": "(c)(2)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=121570589&loc=SL51823488-111719"
  },
  "r506": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "30",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=66007379&loc=d3e113888-111728"
  },
  "r507": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "30",
   "Subparagraph": "(a)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=109249958&loc=SL34722452-111729"
  },
  "r508": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(a)(1)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122625-111746"
  },
  "r509": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(a)(2)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122625-111746"
  },
  "r51": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "10A",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(a),(b),(c)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=SL7669646-108580"
  },
  "r510": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(a)(3)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122625-111746"
  },
  "r511": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(a)(4)(i)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122625-111746"
  },
  "r512": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(a)(1)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122739-111746"
  },
  "r513": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(a)(2)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122739-111746"
  },
  "r514": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(a)(3)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122739-111746"
  },
  "r515": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(a)(4)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122739-111746"
  },
  "r516": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(a)(5)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122739-111746"
  },
  "r517": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(a)(6)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122739-111746"
  },
  "r518": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(a)(7)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122739-111746"
  },
  "r519": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(b)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122739-111746"
  },
  "r52": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "10A",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(d)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=SL7669646-108580"
  },
  "r520": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(e)(1)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122739-111746"
  },
  "r521": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(e)(2)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122739-111746"
  },
  "r522": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "50",
   "Subparagraph": "(e)(3)",
   "Topic": "860",
   "URI": "http://asc.fasb.org/extlink&oid=125521744&loc=d3e122739-111746"
  },
  "r523": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "6",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "910",
   "URI": "http://asc.fasb.org/extlink&oid=123353855&loc=SL119991595-234733"
  },
  "r524": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SAB Topic 11.L)",
   "Topic": "924",
   "URI": "http://asc.fasb.org/extlink&oid=6472922&loc=d3e499488-122856"
  },
  "r525": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "20",
   "Topic": "926",
   "URI": "http://asc.fasb.org/extlink&oid=120154696&loc=d3e54445-107959"
  },
  "r526": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "340",
   "Topic": "928",
   "URI": "http://asc.fasb.org/extlink&oid=6473545&loc=d3e61844-108004"
  },
  "r527": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "SubTopic": "320",
   "Topic": "940",
   "URI": "http://asc.fasb.org/subtopic&trid=2176304"
  },
  "r528": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.9-03(10)(1))",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=120398452&loc=d3e534808-122878"
  },
  "r529": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.9-03(11))",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=120398452&loc=d3e534808-122878"
  },
  "r53": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "10A",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(e)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=SL7669646-108580"
  },
  "r530": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.9-03(13))",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=120398452&loc=d3e534808-122878"
  },
  "r531": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.9-03(16))",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=120398452&loc=d3e534808-122878"
  },
  "r532": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.9-03(23))",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=120398452&loc=d3e534808-122878"
  },
  "r533": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.9-03(6))",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=120398452&loc=d3e534808-122878"
  },
  "r534": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.9-03.17)",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=120398452&loc=d3e534808-122878"
  },
  "r535": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "220",
   "Subparagraph": "(SX 210.9-04(13)(f))",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=120399700&loc=SL114874048-224260"
  },
  "r536": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "220",
   "Subparagraph": "(SX 210.9-04(22))",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=120399700&loc=SL114874048-224260"
  },
  "r537": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "220",
   "Subparagraph": "(SX 210.9-04(23))",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=120399700&loc=SL114874048-224260"
  },
  "r538": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "220",
   "Subparagraph": "(SX 210.9-04(26))",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=120399700&loc=SL114874048-224260"
  },
  "r539": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "220",
   "Subparagraph": "(SX 210.9-04(27))",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=120399700&loc=SL114874048-224260"
  },
  "r54": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "10A",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(f)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=SL7669646-108580"
  },
  "r540": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "320",
   "Subparagraph": "(b)",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=123599081&loc=d3e62557-112803"
  },
  "r541": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "320",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=123599081&loc=d3e62557-112803"
  },
  "r542": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "320",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=123599081&loc=d3e62586-112803"
  },
  "r543": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3A",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "320",
   "Subparagraph": "(a)",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=123599081&loc=SL120269850-112803"
  },
  "r544": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3A",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "320",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=123599081&loc=SL120269850-112803"
  },
  "r545": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "SubTopic": "320",
   "Topic": "942",
   "URI": "http://asc.fasb.org/subtopic&trid=2209399"
  },
  "r546": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "360",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=124429447&loc=SL124453093-239630"
  },
  "r547": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "470",
   "Topic": "942",
   "URI": "http://asc.fasb.org/extlink&oid=123599511&loc=d3e64711-112823"
  },
  "r548": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.7-03(16))",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400017&loc=d3e572229-122910"
  },
  "r549": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.7-03(a)(12))",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400017&loc=d3e572229-122910"
  },
  "r55": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "10A",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(h)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=SL7669646-108580"
  },
  "r550": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.7-03(a)(16))",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400017&loc=d3e572229-122910"
  },
  "r551": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.7-03(a)(23)(a)(3))",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400017&loc=d3e572229-122910"
  },
  "r552": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.7-03(a)(23)(a)(4))",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400017&loc=d3e572229-122910"
  },
  "r553": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.7-03(a)(25))",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400017&loc=d3e572229-122910"
  },
  "r554": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.7-03(a)(8))",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400017&loc=d3e572229-122910"
  },
  "r555": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "210",
   "Subparagraph": "(SX 210.7-03.(a),19)",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400017&loc=d3e572229-122910"
  },
  "r556": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "220",
   "Subparagraph": "(SX 210.7-04(10))",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400993&loc=SL114874131-224263"
  },
  "r557": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "220",
   "Subparagraph": "(SX 210.7-04(18))",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400993&loc=SL114874131-224263"
  },
  "r558": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "220",
   "Subparagraph": "(SX 210.7-04(19))",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400993&loc=SL114874131-224263"
  },
  "r559": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "220",
   "Subparagraph": "(SX 210.7-04(22))",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400993&loc=SL114874131-224263"
  },
  "r56": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "10A",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=SL7669646-108580"
  },
  "r560": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "220",
   "Subparagraph": "(SX 210.7-04(23))",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400993&loc=SL114874131-224263"
  },
  "r561": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "220",
   "Subparagraph": "(SX 210.7-04(3)(d))",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400993&loc=SL114874131-224263"
  },
  "r562": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "220",
   "Subparagraph": "(SX 210.7-04(9))",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400993&loc=SL114874131-224263"
  },
  "r563": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "220",
   "Subparagraph": "(SX 210.7-04.2)",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=120400993&loc=SL114874131-224263"
  },
  "r564": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4H",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "40",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=116884468&loc=SL65671331-158438"
  },
  "r565": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7A",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "40",
   "Subparagraph": "(d)",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=124506351&loc=SL117782755-158439"
  },
  "r566": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13H",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "40",
   "Subparagraph": "(a)",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=124504033&loc=SL117783719-158441"
  },
  "r567": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13H",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "40",
   "Subparagraph": "(b)",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=124504033&loc=SL117783719-158441"
  },
  "r568": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "29F",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "40",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=124504033&loc=SL117819544-158441"
  },
  "r569": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "40",
   "Subparagraph": "(e)",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=124501264&loc=SL117420844-207641"
  },
  "r57": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "11",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=d3e637-108580"
  },
  "r570": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "40",
   "Subparagraph": "(f)(1)",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=124501264&loc=SL117420844-207641"
  },
  "r571": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "40",
   "Subparagraph": "(f)(2)",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=124501264&loc=SL117420844-207641"
  },
  "r572": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "40",
   "Subparagraph": "(g)(2)(i)",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=124501264&loc=SL117420844-207641"
  },
  "r573": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "40",
   "Subparagraph": "(g)(2)(ii)",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=124501264&loc=SL117420844-207641"
  },
  "r574": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "40",
   "Subparagraph": "(h)(2)",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=124501264&loc=SL117420844-207641"
  },
  "r575": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "80",
   "Subparagraph": "(e)",
   "Topic": "944",
   "URI": "http://asc.fasb.org/extlink&oid=124508989&loc=d3e19393-158473"
  },
  "r576": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "20",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "210",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=118262064&loc=SL116631418-115840"
  },
  "r577": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "21",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "210",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=118262064&loc=SL116631419-115840"
  },
  "r578": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-12B(Column B)(Footnote 1))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=d3e611197-123010"
  },
  "r579": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-12B(Column B)(Footnote 6))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=d3e611197-123010"
  },
  "r58": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "14",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=d3e681-108580"
  },
  "r580": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-12B(Column B)(Footnote 7))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=d3e611197-123010"
  },
  "r581": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-12B(Column C)(Footnote 1))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=d3e611197-123010"
  },
  "r582": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-12B(Column C)(Footnote 6))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=d3e611197-123010"
  },
  "r583": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-12B(Column C)(Footnote 7))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=d3e611197-123010"
  },
  "r584": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-12B(Column D)(Footnote 1))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=d3e611197-123010"
  },
  "r585": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-12B(Column D)(Footnote 6))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=d3e611197-123010"
  },
  "r586": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-12B(Column D)(Footnote 7))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=d3e611197-123010"
  },
  "r587": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5D",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-13D(Column B)(Footnote 2))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=SL120429264-123010"
  },
  "r588": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5D",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-13D(Column C)(Footnote 2))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=SL120429264-123010"
  },
  "r589": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-15(Column A))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=d3e611379-123010"
  },
  "r59": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "14A",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=SL7669686-108580"
  },
  "r590": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-15(Column B))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=d3e611379-123010"
  },
  "r591": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-15(Column C))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=d3e611379-123010"
  },
  "r592": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "7",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "320",
   "Subparagraph": "(SX 210.12-15(Column D))",
   "Topic": "946",
   "URI": "http://asc.fasb.org/extlink&oid=122147990&loc=d3e611379-123010"
  },
  "r593": {
   "Name": "Accounting Standards Codification",
   "Publisher": "FASB",
   "SubTopic": "320",
   "Topic": "946",
   "URI": "http://asc.fasb.org/subtopic&trid=2324412"
  },
  "r594": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "310",
   "Subparagraph": "(SX 210.12-29(Footnote 4))",
   "Topic": "948",
   "URI": "http://asc.fasb.org/extlink&oid=120402547&loc=d3e617274-123014"
  },
  "r595": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "440",
   "Subparagraph": "(a)",
   "Topic": "954",
   "URI": "http://asc.fasb.org/extlink&oid=6491277&loc=d3e6429-115629"
  },
  "r596": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "360",
   "Subparagraph": "(d)",
   "Topic": "958",
   "URI": "http://asc.fasb.org/extlink&oid=120429125&loc=d3e99779-112916"
  },
  "r597": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "6",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "360",
   "Topic": "958",
   "URI": "http://asc.fasb.org/extlink&oid=120429125&loc=d3e99893-112916"
  },
  "r598": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "360",
   "Subparagraph": "(SX 210.12-28(Column B))",
   "Topic": "970",
   "URI": "http://asc.fasb.org/extlink&oid=120402810&loc=d3e638233-123024"
  },
  "r599": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "360",
   "Subparagraph": "(SX 210.12-28(Column C))",
   "Topic": "970",
   "URI": "http://asc.fasb.org/extlink&oid=120402810&loc=d3e638233-123024"
  },
  "r6": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "3",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=124098289&loc=d3e6801-107765"
  },
  "r60": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=SL7669619-108580"
  },
  "r600": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "360",
   "Subparagraph": "(SX 210.12-28(Column D))",
   "Topic": "970",
   "URI": "http://asc.fasb.org/extlink&oid=120402810&loc=d3e638233-123024"
  },
  "r601": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "360",
   "Subparagraph": "(SX 210.12-28(Column E))",
   "Topic": "970",
   "URI": "http://asc.fasb.org/extlink&oid=120402810&loc=d3e638233-123024"
  },
  "r602": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "360",
   "Subparagraph": "(SX 210.12-28(Column F))",
   "Topic": "970",
   "URI": "http://asc.fasb.org/extlink&oid=120402810&loc=d3e638233-123024"
  },
  "r603": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "360",
   "Subparagraph": "(SX 210.12-28(Column G))",
   "Topic": "970",
   "URI": "http://asc.fasb.org/extlink&oid=120402810&loc=d3e638233-123024"
  },
  "r604": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "360",
   "Subparagraph": "(SX 210.12-28(Column H))",
   "Topic": "970",
   "URI": "http://asc.fasb.org/extlink&oid=120402810&loc=d3e638233-123024"
  },
  "r605": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "360",
   "Subparagraph": "(SX 210.12-28(Column I))",
   "Topic": "970",
   "URI": "http://asc.fasb.org/extlink&oid=120402810&loc=d3e638233-123024"
  },
  "r606": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "360",
   "Subparagraph": "(SX 210.12-28(Footnote 2))",
   "Topic": "970",
   "URI": "http://asc.fasb.org/extlink&oid=120402810&loc=d3e638233-123024"
  },
  "r607": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "310",
   "Subparagraph": "(c)",
   "Topic": "976",
   "URI": "http://asc.fasb.org/extlink&oid=6497875&loc=d3e22274-108663"
  },
  "r608": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "310",
   "Subparagraph": "(b)",
   "Topic": "978",
   "URI": "http://asc.fasb.org/extlink&oid=123360121&loc=d3e27327-108691"
  },
  "r609": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "12",
   "Subsection": "b"
  },
  "r61": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=SL7669619-108580"
  },
  "r610": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "12",
   "Subsection": "d1-1"
  },
  "r611": {
   "Name": "Form 10-Q",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "308",
   "Subsection": "a"
  },
  "r612": {
   "Name": "Forms 10-K, 10-Q, 20-F",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "13",
   "Subsection": "a-1"
  },
  "r613": {
   "Name": "Regulation 12B",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "12",
   "Subsection": "b-2"
  },
  "r614": {
   "Name": "Regulation S-K (SK)",
   "Number": "229",
   "Paragraph": "(a)",
   "Publisher": "SEC",
   "Section": "1402"
  },
  "r615": {
   "Name": "Regulation S-K (SK)",
   "Number": "229",
   "Paragraph": "(b)",
   "Publisher": "SEC",
   "Section": "1402",
   "Subparagraph": "(1)"
  },
  "r616": {
   "Name": "Regulation S-K (SK)",
   "Number": "229",
   "Paragraph": "(b)",
   "Publisher": "SEC",
   "Section": "1402",
   "Subparagraph": "(2)"
  },
  "r617": {
   "Name": "Regulation S-K (SK)",
   "Number": "229",
   "Paragraph": "(b)",
   "Publisher": "SEC",
   "Section": "1402",
   "Subparagraph": "(3)"
  },
  "r618": {
   "Name": "Regulation S-K (SK)",
   "Number": "229",
   "Paragraph": "(c)",
   "Publisher": "SEC",
   "Section": "1402",
   "Subparagraph": "(2)(i)"
  },
  "r619": {
   "Name": "Regulation S-K (SK)",
   "Number": "229",
   "Paragraph": "(c)",
   "Publisher": "SEC",
   "Section": "1402",
   "Subparagraph": "(2)(ii)"
  },
  "r62": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1A",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=SL7669619-108580"
  },
  "r620": {
   "Name": "Regulation S-K (SK)",
   "Number": "229",
   "Paragraph": "(c)",
   "Publisher": "SEC",
   "Section": "1402",
   "Subparagraph": "(2)(iii)"
  },
  "r621": {
   "Name": "Regulation S-K (SK)",
   "Number": "229",
   "Paragraph": "(b)",
   "Publisher": "SEC",
   "Section": "1403"
  },
  "r622": {
   "Name": "Regulation S-T",
   "Number": "232",
   "Publisher": "SEC",
   "Section": "405"
  },
  "r623": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "10",
   "Subparagraph": "(a)(2)",
   "Topic": "848"
  },
  "r624": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "65",
   "SubTopic": "10",
   "Subparagraph": "(a)(3)(iii)(03)",
   "Topic": "848"
  },
  "r63": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=SL7669625-108580"
  },
  "r64": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1B",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=SL7669625-108580"
  },
  "r65": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124509347&loc=d3e557-108580"
  },
  "r66": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124431353&loc=SL124442407-227067"
  },
  "r67": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "5",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124431353&loc=SL124442411-227067"
  },
  "r68": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "6",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124431353&loc=SL124452729-227067"
  },
  "r69": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "15",
   "Publisher": "FASB",
   "Section": "55",
   "SubTopic": "10",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=124507222&loc=d3e1436-108581"
  },
  "r7": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "50",
   "SubTopic": "10",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=6361739&loc=d3e7789-107766"
  },
  "r70": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-03(12))",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=123367319&loc=SL114868664-224227"
  },
  "r71": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-03(20))",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=123367319&loc=SL114868664-224227"
  },
  "r72": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-03(21))",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=123367319&loc=SL114868664-224227"
  },
  "r73": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-03(24))",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=123367319&loc=SL114868664-224227"
  },
  "r74": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-03(25))",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=123367319&loc=SL114868664-224227"
  },
  "r75": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-03)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=123367319&loc=SL114868664-224227"
  },
  "r76": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-03.2(a),(d))",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=123367319&loc=SL114868664-224227"
  },
  "r77": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-03.2)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=123367319&loc=SL114868664-224227"
  },
  "r78": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-03.4)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=123367319&loc=SL114868664-224227"
  },
  "r79": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-03.6)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=123367319&loc=SL114868664-224227"
  },
  "r8": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(13))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r80": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-03.7(a),(b))",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=123367319&loc=SL114868664-224227"
  },
  "r81": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-03.7)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=123367319&loc=SL114868664-224227"
  },
  "r82": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "2",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-03.8)",
   "Topic": "220",
   "URI": "http://asc.fasb.org/extlink&oid=123367319&loc=SL114868664-224227"
  },
  "r83": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "11",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3151-108585"
  },
  "r84": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "12",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3179-108585"
  },
  "r85": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "12",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3179-108585"
  },
  "r86": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3213-108585"
  },
  "r87": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(c)",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3213-108585"
  },
  "r88": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "13",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3213-108585"
  },
  "r89": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "14",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3255-108585"
  },
  "r9": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "1",
   "Publisher": "FASB",
   "Section": "S99",
   "SubTopic": "10",
   "Subparagraph": "(SX 210.5-02(14))",
   "Topic": "210",
   "URI": "http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682"
  },
  "r90": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "14",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3255-108585"
  },
  "r91": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "15",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3291-108585"
  },
  "r92": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "15",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3291-108585"
  },
  "r93": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "15",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3291-108585"
  },
  "r94": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "24",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3521-108585"
  },
  "r95": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "25",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3536-108585"
  },
  "r96": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "28",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(a)",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3602-108585"
  },
  "r97": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "28",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Subparagraph": "(b)",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3602-108585"
  },
  "r98": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "28",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3602-108585"
  },
  "r99": {
   "Name": "Accounting Standards Codification",
   "Paragraph": "4",
   "Publisher": "FASB",
   "Section": "45",
   "SubTopic": "10",
   "Topic": "230",
   "URI": "http://asc.fasb.org/extlink&oid=123570139&loc=d3e3044-108585"
  }
 },
 "version": "2.1"
}
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>ZIP
<SEQUENCE>84
<FILENAME>0000318154-21-000045-xbrl.zip
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
begin 644 0000318154-21-000045-xbrl.zip
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M6'2)T.PZ5]X0=!&GM%C;5(\#PBA25'NQBC#U&VF\&.BVG2MO")^2*W)V%]<
MP-,/#+%7B9YUU&P:XV+PV8-<>5,FQ41-!)J[0\BM<:I#LJ98P;3P%@/5%I_
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M(Y;YSQ3O9AU!;%U*2Y6U ?9I")AB%QL)$N'E3J #4_9TUG@WB21@+22#  R
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M/M85/WR]H>K5"=_=O>=F<GJ^?OJB+?3F>74M6P!;;U70VB 84%3)"F"G(2E
M&&D&&]RO YVM\C3-A"JY(:81I\*;"*;*@V48YMJUQ)'*#*BR ;3RP:N\A=@/
M0Z*%7C$G\#_DE-$,T(4L)VPW@RJ["$"?K!X^G!U=+ CP&,&T*D2+J $'\M3G
MH.?2Z\V@RQ_%@0-=GK=%':$%2-,20T@845)7K:5SJSWF<#/HLHM -$NZ1&G-
MI:QP#PP%1= #4_"_(%:K)=\,NFPO&-T^.;:GMWG]DYU]?G[<YT,3 .>):*(
MF*.0Y(H Q5*,QC #FFP8F;V*?OM"DYPU4BG-0P[#D($)M!JTJ<4S>VHT YK,
M*OC,U)O4/%JON81B"L$\=<Y).B09+2+1#9&TUQ]T+E9>7(SMWGUPLCZ[9^M'
M7SH,:SL]^\1XO3J^/SN]DHKGR%9<Y:8($ *V&,&X^M]20I6;09WKSX862!V6
M-DJ>VFB7!HC(DD1).4/H(X]#9G2@SN_O1<50@G9 SY*@%R(,8WC$"L3<;DK
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M:NSH)GB9X-XD(+AN:%/[LX!5#!$&#DECVCVW]Y2Y"2@A1:W:XK3,%W(QKCR
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M9G2@SN\7[9DVLT RU :A%K+D[%$=61DHX,V@SEQ4J&5'*E3*205, JD%38V
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M$-.04LN($@_3;PN@\[^(BU]\\LW!3-[&3&K(W".F,&RJ/,0XJ(9I)T>/11+
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MA:&"<64YA9033:!4-LCJ2V_FVLHZR=,34^<5M(0*$9TN2EA0(I7P5-IH%"]
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MSJVH1F[%>*G>C18J$MS:I64:AVDS8=V+L&J3T0IFF8*,(J"#CX055120PG/
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MNCB@1&F@45" >T(,MQ8Y:*;4N30S7&:X^6:XW!!U;A@.G3.<=4%A&0) 5F)
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MC[XAU4!+&*);2 5BW$LDTV'29?KXY)2\DU1=2,\TH),A_020OK T*"0$,>8
M4RG<$P*):,8!V-1?3L<?W(4$:<6KM#F\\.&):W6\<MIK56R-<FDFPLV9AQ[(
M0[N3I@4DED'F,4"$.$"5URG8; '3'@?-&$62I0Z7D7$JY/#D>,4\FA89P=-#
M\(4E864(F!D"'(+1.>", <4P!E9X:(BG7H51CUI<I<SUO"N4=X4F,H/C.^)
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MNS@M^(^3/G0$_6)8\.)IH8]J.M'5!Y2.Y20U4,L!;;IH-452LBG@5M>6FNF
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MCT3ZD(A%G!/TLX!FM,5L:?=M]>76F173#PK3BZCQ(#VBVBC*J/22^:04BV#
MF6Q\AFJVMP/F<T%#KE*)F0 )P0/"G"7B8W D""&B"-0F9A'FZ_SF_<3JR.#Z
MREL<&=SFS)<Z+[B>!%8Q53'=G2FFN6$YAZQ5S%(;8P6 =]YFZ97,Y]5;YNS
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M3,$S6A*X;CRPO )X)3S!*J8JIBJF^\YCKNKP;M7A7#YS=,Q"3(1QPXE,2I-
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M;TIZI<5*BP^3%A<Q)KUS)@1IT &7 LT0KG,0D3,M(2I_772R^M]WS)1S!RS
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MAJ/1>J<//V:_K*Y7U8I(2".#[J ?_>A@XE@]G4S)JM2S"/7,IZ3X**.F0$D
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M2F2]MGE%IOS#.'1JM\EP%BKK'/O3$BBKL81[2$ZY/H+Y?"*52C\+T<_.O.F
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MKH)\E4 ^EX#,G4HN4R*3S$1"-"2@3T2B1"8/FF8!K("<B@<X\;/][8BN,U,
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MI@CF>"X!LY @PL8V+=\2@?C!E$,^F^2/@Y6-:WS?<D@\'F6Z+HZ_93GDM>3
M%;MO_>1 1!D%9JZ-(CF0M./UJ((BHS6<DUK?7"K+)@=>+ 0V4@A&TP*R#)(S
MB)H$0+2.62\B\&2#,Y+L,7]7H>\ERO-I$#Z#L,AD>07.)2CZS<B PH PI,Y)
M952#\#)">![8B"48CDZP(E,B:RPJ%K(JS*-P&JVTH:O=$- @O+X03K4SKHS:
MIN(A@O%:<9N\Y\$DYWB#\!)">![8*-)SE:)CQHC"P (RC,JSH+TKJ:@HG=G8
M-ORNB@X:A)<0PEG[$$M6*C@!MI:11^VL\CF: IHWK^@20G@AL!& "!@",]8#
M Z43"Y 42Q8A"$X[&!4ITJI!>(TA;+OT/F5K4WH0,F*(7*N:/*8B+UHW""\?
MA!<#&S;:'#U8)IRQ#&KOFR ]&<=D$"DD&!M+<M@W#*\QAKVW*1M+Y.TXB)*\
M1#3::(Y9&P,MOV I,3R/:Y -)+$@,.\5"6(N T/O(HN9&R4PZ6)M3=6]=8;!
M'8+XP=1K_.\O3_[]:%7#&JU<X^%$MTW(KA"^5<$,D62_$R$*-."D$]&U7.^E
MDP+]\Z@&W]E[(G<_O+4V:LPQL82.)(%)G&'0P"P/4FMADJI%&\K*)8IP-R#?
M,9"#R-9KSEVLY\QJ':  )M((?,[12-F O'Q YI> K(123AED28-@X"*99:@5
M0UVXU(JG[/3&MH!;!RD;D)<7R+8$G4RV/#L#$3U*\$8GM,*@]L4W("\?D.4E
M("/XE*QW+*=,$CGDS!RM(=-&Q.R2BD9XLLW$YPX!;T!> R"[HJ/1AJND GB-
MWD8.@7Z-DC ;;7.P+!^0X1*0L_<AUS"E=U;68DK/L'##3#WQ70D2RKFJUK?O
M#MZ O+Q +K)X%5(AF]B"$C:(A#P$Q&05Z=<-R$L(Y/-HQ^[C)_1Z?%MD"%X'
MQ3B90PR\DXQ4JL*4$3ECB36'J&8/M8*L-4:R2;6_E<$DC 4/M N"5)E'U-*2
M6=5J.982R?U+2":A+$!P!AH2@Y@,0Z,C"Y)CX@6B,FYC&UPKZ/@.8-S-)[4B
MH95T?%5)QW'>+_W!_HAFL'_8JCKN(R7<"F>M]CF@!]+H EEK I46/(<B?&N4
ML80285[5H0%D(6N:N6 T*75*,Z><8]FC1$#GE,5JGMVZ755+9%E>"!L0(0NA
M(P8#J7@G$LB8DI?5VV9%@_#R07A>U6%5+$2WM1)+>P89.?/"9I8XCRIXE8*H
M:2RM+FN-$4P*.[&X3AI" BUU""X'0Q994K0-S'4.W&D(_DXACP]O/2V6KPTR
MI*I%'<F2$)82F/&D3V%2BAM.]IAH$%YC"!.)5T>:5Z@1M"_!&Z&<#"4AAN8C
M74H(SXLZ?+$B5>TYV\0)PL4Q1VO%,@3D.24LVE>72BNM7&,(8U9%.R0FUQ%R
M-L&BS@6UMDE)-3.%&X27"L(7CCE))1DO.0LN6@92&>8U!Z81HRD"4*'8V+:W
M=HLV#"\OAIV/O/!4FU454J9-$,(1H.NA7D5;@0W#RXCA>5&'(<7)61>8S5HQ
M<-HR)V)@X&E-74HA^EBMX672I1],4<>C$1[E\7$+;7Q-:"/A*.3C89[TCWHX
M*-BJ.^XCEU3Y8KP)7HD$ELM .H+&;"):,%8TQ\JRB8-GBX=Q&)]KXG=F#H-F
MH$5D7N;"O"BDZ8D@LDPU'?S69;HM965Y(5R\<=DH:8OU$+5'']#H$E7-0'2E
M07@)(;S0LTH45YR-K&:F, C.,:^\8E9H=$K*T$4W)+1$\#6&<"3E'4.P4N@(
M-DH4&%&$S(UQWO'2(+Q\$)Z'-\CD*CH 5-DK&5CC:@IX8-(49TRT4IJ:8^!O
M?7QL@_#R0E@'E8M EVW1H&-!T$Y +B9&D7TNS:^R?!!>"&\8STE;=DP;\ RP
MGH%*2\2BU-RBTT9 /?E4M]SO-8:PT6 A6*<AF2[3+V;D7(08T=@28X/P\D%X
M,;SA/=>U4(.9G,@:1AV8*T&P$!U',%P:7^IA'$T.KS&(DX-,@E=K8PG$P?I"
MTE@9;UU(WF1H(%Y&$,_C&UXKQ%PXX]EQ!@(+\]P"DU8FGWDNNDA2IF^?:-!J
M-VZ.P^?Y&"<'K73CJ^(;^0^Z4[QMWZH6Z+YNRJ@/G >;C-2UE3\XFR.ON<(A
M10#9^H OG2!8/(U#I +*N\)(%'0'JUF&T7NFN)$AN5)RBF20M2;"ZPQA)VP*
MVDJ#T8)+-??;BQ1RD2"]FQVLUB"\5!">1S:4C3(X-&1_837'BF9HH3LJT7"C
MI"K)5 C?NC-&@_#R0KB ,]J'X@$R@)<("0M:X;/E3B7>(+Q\$)Y'-FS4P5DC
M6"PFU-,X+//29X;")\V5Y3;RC6UY^[Z1#<++"V$;M(! R.5@2!'3#J,(OGCN
M;/0YM3;@2PCA>60CAVB#$8IQZSP#[@G"(6GF8_ >(PB!;F/;-P2O,8*-CUX9
M8RQ7"3)&9R*6DG0]O#K1_QJ"EP_!BX$- 49RG10S F35I W#8@53#@C9UENM
M7.U,U33I-08Q3QF-B-9JTRG20?G(T>0L:Y>R$AJ(EQ'$"Z>,ERAD<9:A3[7X
MJDCFDM-,&(G)T_^LK+HT;X4;WP&'_WS]V_-G_WKZHD4VOB:R$7%4^H./P\-^
M.Y+C?OK9J.@A:$ AP5@(J=1C;WTV-H/TH3E5EDP4[.P]FBP>S.0,K1;99#Y[
MP4!8S8)&SP*2/$_2I1@]Z7.^99NM,8BE*"8Y4#7C&Z+QCCLRT93&G+,5N77Q
M7T80[\Z-LA#)I/8>60P!&;B"I,_1C]IC3 A+[U6CS+>3.-88PSQZFX(O18&'
M[*+S1B!)9N6M]R27&X:7$<-S01P@*H]&U<"D8H N,5^D8RA*=*AU] G()O.M
M>?\:@UB9)+U/(FDT(&-$H4W6Q.$1 M ^:(Z5)03QL[D@+MQE2_H3<PH" R4S
M(QU*,ZZ254J@-:6F"MD&XC4&<<%4@HY9.I#@ZQ$ZFNQCD<$45Y)I(8YE!''W
M[T4%,MG$)19K'+(4+:%86LG0*\,4>N2D8F67[,:V:V70:PSB4%7I@EG; F!(
MCRX>M 4MG:U4WGI3+2>(GYZ#6"6I D ];!PXB6(3&*G8A@5.*,XR992>].G;
M=UM?X>*-[X'!9Y.#/.H=CX;I)$[&EV>YQ6GOU*]'^J@5 9-7$GA(3@MTA2.B
M<E;IZV0\EN'H$"=TK3\G/QZ='+(TG+#9)QK#W3?#/5GTW&,)(:KJ(3#.,M!<
M$<'5\W=#T3ZG>H18(%MCD^N64+7&&!<<8RHI%N,C\"A)0TW1))6=*$$IV_Q^
M2PCC!=^]-\XA&"#%)-AZ0)AGWDK-O.&"WJ)7"]_8-K9ULUYC$$OE:C%@<;5
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MIX%IP_)]8_DLK'*&Y2 TTLH8%K$V*BW&,:>"9UII3-)#SE)O;(.0#<GKBV0
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MZT@T[>J22 F/AM>N\NCKB7"2:6T\=Q(@YE!%M;VS$S%;'<D-</IHA$=Y?/P
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M3Q- 9"XR\]F392^-9<'DR(+($6T6+N?JOG.;7-Y5YN^JT$-3E)JB=+DA:>3
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M*Y53MYY=//'DJ-/N:,"DX\2#S]_FTG5I8_QZ0E><J::Y(XDZSN,\F>J5B^Q
M5A>I,">C3G?HS+TJ3CX,28L]'M BTA*].-?]=H>33@+27#[.=+=^/HJGO1]F
M+T^WR56;HUOZQ7U*(]C!J50Z'^M49,YO>W:S<<[OZ^#.]?>Z!<ZTG*D"/ 5D
M57B/SM ]O>7P9)#.M-/^7'.K =H9*W;Z0*F3.!K^V:_Q6QK.?]P@8<^+8*Q6
M&$ ">.U]%MEQ+R$%I07W;Y]V[DZMQ(4\/7>M/#T\)+GTVVQ//CH?_;G!?&X8
M^X=F%[^+ZMGO;[.,%J(!IAP6!I(C0Y,<,[:44@MNA9<;V^H*W^<T#R+T!X-.
M'!X/3F:J(.U_PB;I@@N;I6Z2;D/%;D.%/%,LTVR'A7RN:-,F/#GNU/K[WE'7
MR_SL=A2)!9R,^AV;T2YZ=O3I%ENJ3,][WUS[=7.IVER[J,",*8HV%_WFLO0L
MY.YX"&-]*AO;GG\N4_-PNKDJO8P6)GRJ.<^9G]3]414DPZG:>]G(FYJ<M!^K
M8)[,"'UT2%\,>=#/G36!DS-I<&Z&GJ53G O),SJMVEF5'Z2@]6H4E"Y9:;A*
M'1IO[X_^_G T'=BY-%CX]IGE4E][=T+J37_:PI_>&Z^!VBWD?]:(\8*)WS_J
M$G(NJ5E'G?;TEPH52>9/M";5"48X$XQZ:KROF.JT2<.D6<?1= ##\8+6]$4]
M\8+>]35JUP'2C@_UR3H%K,[:U^M?6/?X./_?">DQ^<S!-->(!C15^WCN1:IO
MUD=B4X6W\YEN7N]NW=8YFM#:]8\J2=.3GLR6M5^S6VGN:_K8\8!V%LUJ/MK'
MJ=>.IBJ>C,?3QZ]0)#-W4KV!%ZV;O]X#=[3PBY.@6+=_IY,P]5H0KW3F=_>8
M)X3CT<SVFXZKFG^?PX7I=HD]VR7N_((=/KYP5>Q-HQ7=%N\ZQ4S-V7JQ1>?#
M11MS3;CJY_Y15\Y[CH#I)A[G+FX[R'_6E$1:T''UC]0M-NB_K_I(!<IL)QS1
ML_1H0T^]W-W4GTF6NG$Z\33+:%PP]@=]).5IMJ7&4VWGN$HX^C:.I^+L&$EZ
M5!-Y5 V%O/D7!N]FO4*G^,\?XNR]BHA.,F*<L0))GOT91X0JQXZ'D[J_:91X
M9F]_XFSXJ7<P_$ /-=I<=-#/9JD_.?<O_X7;J=[ZY.B,4:^:]-EDS[P)@TFG
M_M'@)]U5JIUQ-!W8V:I4I\;</CG&T^ECC4\";>*CF4-_OW-R5\R<VS?C<[6A
M8\E."^VH$><YJ)CH:<>=KDK3<J9?5*?TU U8N:]6@W0>OT(;Z:B3YAUZNF&<
MP_!HV!L,C_8KM"XYFL_,J(6=L0#/\26H3R,H=2 CVF,5G)==H-RO 3([Y]WC
MJ7OV:\))<^?TV6+/I/?)T8*;M,YUR$>YH_H?7N[]G0SP,QLYW<C@N&4:U@UK
MSEXN/ 3)VK_/'N'I;.CCYQT<:.ZZJK0I]__6R1GZ]&]G:NV#-4YV'[_4._MO
MR=15J!.R>A8E ^<B"REQ1HNF%<>LHPX;V_93VZ1W9I;4_7B377*_1>MME]QZ
MEY )ZQ RU[&PI*VL&2.<!1D#4R"3E19#X+'6&W[!A+V<17 IZ-L9M.?VY@3?
MD\Z9YO0WT]^F"06]%Q=$&_TX#^P2@]4KTY]7D6*_+,2(-F>.%^Q":I\)YV]]
M6@1U@Z*GV^:^M^*(+\M(P>^D.L*TZHAO71VAOWEUQ).9OXM(_,4!+D]IQ&[_
MG+D_$O/"SKOT;D<^T3N/G_=W/^[HU^]V/KS^>#!XO;<OWOSRN]J5+_6GS$WW
M?[=_NBMW/K[>>_]A]Y>G:N?CH+_S\>_OGOWR[X-GC_]-XXF*6+T0@XNWV0J;
MK4&6G*HGE^;"O-)=7RT?.=H /GU2&!$+IGH>"B0+%@6&&#$B<L)-D (N%T:<
M37@UXGOC.N5?4Q[QI9NNL :_-[,/3R;G5BF9MK3U\R<SU_OAR6\O_E8-X7/C
MMXJTZ>5S8F29C:I'9\%3T9EBAV0+3*\PKE9B%8S5IS,-A5VZ=^I7XD\]NM.=
MW:A3 KL+5\$Y-Z,O?.&L"'+N@)R50IY=L/-C54NV!D;&751TZJFI]QY/",.]
MX?'D3(^8T-:JSS%]HPNEYE&G&58G7%5 >_@!1UT2ROX(#\FXH14?S+6/\_&.
M,ZD6G7'_MTXG29F(_CS9X&1\;G]5E?%D=#J[Y6&>' PO)XE\6W)[$0]R.AGD
M9^4RS?V][JA'1^GQ='7W:D#SX5+?ZX]ON>;1%IY9(4'/@"Q0$N#$A)!#G6.L
M-0V7J6QM.&;J,)FRS#DT9YCOD@*P?F(P&'X@5/2/SFPY@FC^,Y+27*'$IHR4
M<()_^_'KG"E3/;&V[^CBZQ=[,E0PXO$X_WCVRT\U16> IS_VC[H'[+[TT\4;
M7%%XW]UO^O9<Z=KB4\5KUI!Q=N?9VUO=6Y<:GTS? [WEI/_LVWQ+?/:]O[JL
M$%M&?-UE__H]LM';8%=JL!*N==DOM!.]8=O]R?#XKHG)7:MCU=6]ALX?R%_G
M@6;6YOT_TM4FS%[GA5UTOG8VV05?PS7ZH7ZQB<V*S4VWW+N7_=)?F)J[W>7?
MIC?;G6ST*SL2?;&/UI=7^GX>^>K%KDKJ73WPS5HYK?[$\;M@B#6=F[:I[F13
MW=.)/M] UERS&^:L(\</G;&-D^%HP4RYW<D-M]M2]W2\1!OD/0_R_CO\?S]L
M[>;)62[&9ST)-^T@^@ :#:]I+^%[S>N@K3=E]G\-Q\L3>/]*'^:L2_ C^GM'
M[1[^.J"QO=]Y_/O'-X\?Z=>O?CY\]KCZ,P<'NWO[?^Y\W'WW29?@QU&]_ACE
MZ\.78N>7WS_L/MZE[P\.7K^B,7S</7CVZHEX]IC&)'?+SNFL>?P+_N%M5@EM
M=(EA](Y!=H;Y$CS+G$M(DH.'5,^5NH-35/Z"YY;TQ.9&1<OT;#>@HEOVC&E4
M=']4]/&<BD0I"K+5##EH!LHC0U$\,UFI8&(4B0<R8#8[TZ]14:.BE:"B^\UC
M;%1T"RH2YU044_'2E<)$=)(!1&2.Y\*X-)8HB2?C<6-;;7K?M*)&1:M"1?=[
MV$NCHEM0D3JG(JY,#&@*<Z6>(A]R)"K2P$1)5B6C=(AQ8UMO&O!+1$5?<4K+
MNI^WVT:Y[*.\(\_M\KIK7TP3*']XG(^&7='<5P=#5N3$NW:-VVSOOSCV>-D#
M$Z\N9RC/<H?G48HK(A/GD_+ CD:?SLW=>_,OZH-G2_)HNB*[7<KXLS+EI&?S
M)/$N1;GIBS?0%\]/@ZWZ(B9ADB^<65[/@X4 +!2N&4A+VK_4H61.^J+YM'OO
M]SL4_:[5@X;?.W&!-_S>&W[G7O!JF9>@"JMV'P,-DOD F@470LXZA&@DX=?I
MAM^UQN\=^(T;?N\-OW/7L4"=#.3 !(_UU(046= "F 2O2N$Q>Z4(OU8V_*XU
M?N_ V=KP>V_XG?M;HTK*FH(L!\D)OR6PH%)BWAE2GVA)4^[DKULB_#ZDE,,G
MLQX<Y:K"W*^RZ*\;UEIY1KH7BWY66?P)+3TZ;[78N.DFW+28K"<4Z7^%C(%H
MN"3;@ P$GZQD,>5ZFG,HIK:(54L4![IKWV?#\7U9]@W'=XWCN8T?(Q=$O, \
M:8:$8P32,1PREXSAF!1J'3>VUS"UI.'XWBW\AN.[QO%"FICBF4>IF?2%Y#$M
M',GC>K"MY2E!D6 +;SA>=QS?CZ7?<'S7.)[;_"5H*XWV3$"I\IA'1HM$B.:&
M$ZJ11R66"\<MEC^-Y?]%G>%-O)'7KN]>3P*[IU#_YRBL$=<-B.O9/Q8< DKX
M[++)3&+6#-!Z%D!()D4PJ-#%X+ &&S[7</>FSLJ;]$%8E4C$P\;^?:4)-.S?
M#?87RN5"M36$)WTE"P;621:DY:Q83VJ,]M*$7 ,5MTX+;]A?4^S?5XI!P_[=
M8'_N>- A*(\2F3,\,1"FUN^GR)STUI1Z*$.J12'V<P<1-NP_=.S?5WI"P_[=
M8'_NK- Z>&658L6YPB!PQWQQGF4(1.0I*/I)V/=WE6#TS;%_)[5B=U@\\0WK
MF]HHUV64:]\V[^^?JY*Y=6;?"I>'7_6(*ZH5G(S3V:$ =^L.E%\Z:N5B@B)O
M\O_+!>%[CZKLG_K]'KW5WB5'YAHK9+XQR#JQ$-$P02H<U\F6%*$>0Z[6,,>X
ML<^:L\\M'9*-?;X-^YR>LX\ GZ/TAJ6L#=D?5C-OP3,GM<M:IP2R8Q]8PPJE
MQCYKSCZW=(DV]ODF[+,[UWU$(NT'@V1"2V0@(Q+[2,\@&BF<3P6EV=@V6WZ9
MZC,:^S3VN9;E=3NG;&.?;\,^<]V'"]#@I&"<&V  $!A*;AB2M1Q,RL[4A$^_
M96[=H73YJL.6UU7UN#6;7_]>AM_)637;6XTT;T2:3Q;=55'2?UT]3IB+P,B.
M%RQ8CDR8**7T,EFM.W=5:^O<^&?5^.=;NZL:_WPE_\R5MIRLT. =B[(FR0H/
MS$=A6'(E6IE!%IXZA]4:%LXV_EES_OG6#JO&/U_'/PLNJ^"\D3XH!@9-/6*G
MNJQB8BYHZ9*RZ*WM7%:-?QK_K!K_?&N75>.?K^2?A8"=1<PZ&!9U<@P<DOV5
M4#$O'(<B2$O-OCJM]-(5./[7!,,@T_^G_A_;9X/KSO'LQ^W_IA?/AK)P[5H-
MVR^GT]OUCU(^FOPHY=8TF_">0=4=!/[S<-2;'&3Z5P\$KX<C'ET^_KIWX>CK
M7A74W0<K8C:[+Q]UZ;2UZQ$>3?KGG8_RX?%@>$J7'4^&\3T+.*:+X0<<);KR
MGW%P4B]>1L/#[B)Q>'A\,L$.VF?]DZ9NL]X''/>.AI/>F*:P7VA5CB9;Y\M^
M/OL5^?VCD^X*%^;_$$?[_2,V7<+N)-I/5V0V_=O=6=\7KUVOU*&:!])GO!&:
M9P7T\ ZU+9BC5/0OH7XKN',;BU^[^0"^W?I??1"\V>K]]X6=>P<*W$7._,=P
M,, P'&'=$X]&(SS:S[4@_'%_' ?#\<DH[]'M_CZ@+?)]V?//G<?[\"_YYO3U
MJVB>_?*:6//IQ]>'OY_N[CTB1GO*7[\[&.R\>G.P^_'1QV=[3^3N.QJ#?/E'
M^N7?D/[GU\$;.?@CO!O"FW?O:5R[_3>/GXJ=QX_XSKOG_6>_O/SSS>$3M?-X
M1^_LO98[O[S\^.;?3NV^>R\KJ^X^?J3J&-\ZCD$[+9C"G!FD0GPH>6;"*P<>
ML@!>IE*.]GI.C^IQ)QETB/0AYY4@-4Y[TN>"S1DU+RZ W^AE$E#'E8I&)WEC
M>V%)AD?C3ZCKPNZ_!*SI"GWYAI<&&'D1Q=JH9(2H,02M)4_:!!T H]BX,5R6
MAT&?'?5^/1F<GG/C9N\#D1GM;"*OX<FH*JKSR>Z(<]"/^6A,,JB'^\2Z%0R]
M#_W)0>^?I\,/V/MG?]0_ZOUCN+79^]<D;?5^^.<___&WWF38>S?L'TWH3BG_
MD0?#X^Y:Q)JT:K%/D_.Q\G?'P.S9_P+OE9,!??C@A)ZP\OF0QG2$@^X#89A.
M>S\\VOFE!UK\K?=A.!JD#_V4-RLO$]OW: "_(DWF5F_VH5Y_6M+>R8I1QJZG
M0\?XD^$QL4;*]>B=_J0_WIP^R_%P0I^@<=5K#>EKHQZ>3(;]P\,3DB^I/\XD
M#L9;GU+M2FZ"ES2&V>301(SKQ-0_SM>WVQ0?^H-!;Y Q=>_M#X:!9F>VF-,/
MT3A."FDW)Z-N=UQ:WW/9.%N3*U:+MLKT-G'(CDFRTB*<KV"W+(\.]_-1_4(=
MPDO2H*M\)ZE+4U%O=X DMX?'=5)[G1XTKAOOBHO1^W_@J#\\&<\6E];K?::/
M#T\F8]I)GUY_LY[%3#*_/AE]^\G):'@\U3@>C?M(8NAN!?KR[(W/4.@7*?$5
MJ6&8.E"?').:1'@[QM,SW/W'#8[6BG1MHQ A\0#9N*"D,;43?["B2!1W<_8Q
M'M+LOSS^N8[TM^E EZ6.ZON+]G>/Y%N'46?TAKEH) -3FX9864--&"0J!2#U
MQC9MHL]8.K0W!W6E"9$5YY,#G'2J\2C'(2G&'PEJ!*SGF:AU% ^F)YW/V:7W
MP_/_AX?'/SW^&]'&,0F@?$8#DX/^*/7^[P1'DZD67S?!UHPJZE7.6:4KUNME
M^F@5+5>S&&V]\63\"3=M=E?J6&'KQ=85O-9];:OW;,8?,P;]E*+.KW;ZN8M4
MHCD9C>AKX70^]I!IHOJ'X60TGK[3/=]6KX/9:8]V^G#ZF?\[Z=?OTBP?XGMZ
MLS_(9,"0T)JAKV/WD^/Z@9N 4*02I<YD0212Y#0/,13IC1&0.=<(;Y_>%GO/
M:1%(Y7H^W0YU/#MG8]_)DX-A^NU,)O]\0B(FG[\[0^O2G(.W!'!]^N$M #<B
MA\BXPNJ9X,A\EI*E$KBT4@FET\:VTU^"ZY3[]RLT3HZ'4\AA/.C3:IV1><RC
M"5:1F_=/!O7@J]->7<O)^)(.T)GIXX/A((V[C=MM[&[GTM[LMOJ"B3RK%&.I
MO]^?]$;#4QS4+L0]&L(,M6-:[$^1NO6I\.U]5DV[B>#]G'%]L;02Y+3CT_%P
MW.WA'T=YT-F./Y&&.CDX<P8N?'&F!_#Y5S",A]5]\-FO_*4&0=HY$>'R*!!"
M7-*-%GY>WSE!5MG9EP[.RUF/<3^S0/K\>X:%'OI'''S T_'&?UV<+9JJ2ZOS
M51/[53MDE;PI]IM[4YX>_9&G#?7&3X\>YS!Y=)1V.M6[.B.?D.R:G+XX[SA.
M;_YC2BU[(^SZ\8W'I*0OG>N%/WLQ<UR_>_GQ];M'ISM[SP_>O'M#Q/W\8.?=
MX&#GEQW]YM634_HG=@Z?_/GFEQWU+_5\D/_G.;V6CH,$L[NWVZ=[_+G[R\^'
MNX>_OM_]Y<GILU=//KS^.!B\WON5_KT\?;WW\_O7'U/9??Q:[_[^5CG)@2?/
M= F6@8V6>:$5,7ZQ4DI!>O(GO@RNC+.HN,2DP0NDE7/*AJQE<$Y[<]G9LK!B
M7^%I^?+=+H[."6= U6]H#T4(EZ(&76CCE6C V9NC]=M!J;OBC_T)W2Y>@P8?
M_8']0=WEC!0B5F47B:R%N;TTE]\0A!5W"R [&]?/P]$+&M5>_?WA BORG4=O
MD^.6-*/$"@^& 5>.A< YRZ%X2%)YT/DR4%;7PM^K&MWA<#3I;+!J@VSV]D?#
M\9CL 9*M@^[E?6+A\16O$Q&/9Z9-P?ZH]P<.3G)G8_2K&D+[FP4RZ*K;9'Z4
MQ&;OPT&_VGBC&C@YJA93M5GP$XAL5DMG<GK<&52S[Y_V/M"G>U@]>H/!\,.X
M]P/I?C-U=;QPYNI?2]YI++V3.W--K&M5T+D\C\?YQ[-??DK]\?$ 3W_L'W6S
MUWWIIXN7JUK%Y:3MNL#3M^<*QQ:?*AVSG/'9G6=O;W5O70H%3M\CS458^.S;
M?$M\Y7M:??ZF?_7-OQJLD%M*?]UEVV#7;+#F6I?]0AW%#<LEODVBA_N2$MTA
M>X_8:KQ 5]5FQ>Z%3P/1US@>^@8M6/YBDF8VX1)-TZ,S@=/93%7H/.#)^*5*
MU6XBYI*U^[.3NFUB/IV8J=KQ@&?F9U*VNIF8*EP79N)K^R?=I!O9\E:L=0[Z
M/=HMXY/1:4V\N=8^N?."X=NU0%SAU,P;/__JYFU>BI%P+4G?,2% 2(#1HC#6
M&9% !&Y!R,_'2"X:Z)=-\DL&^YGD_ <)S5IUO#2!CZ\UU\\2..'9+Z_%[KLH
MWQS^KE^_H^_LO=:[KWY^]^;P#9GGU81_S=^\>GGZ:0+G/KQY]U+N?J1//A[T
MR<3_<_?=>_'ZU>[AF\/G[W;>/>%OWCT?O-G[M>R\X*?G_1YMX"4Z&UDLI3 P
MM>:X),]L2-%(65RJZ9OZKBJ.5Z75:^.VQFUWQFV+\=_2_S,G]C&/AC?DO!A/
M#FML,:=.)7QYK@W^0AKRWS/=(^_AGXT(;T:$?'[81:@=IC QJVMR!PC+7+#(
MC.169 E96;=!K.>DD#\U-FQLV-AP&=GP7_178\.O9$,Y/_[#VIR,]TS%2&P8
M?!=8%0PMVB#165&@L6%CP\:&W]3NG3/>1?YKQ'8S8H,%8HL\!.*TK (R4"4R
M5XIF*;B8I,V1FY6R=]>^_=9%9V;H#P9?Y\QL9\Y>D\M<"ERJ;&4H'+3EWED#
MT:E4,C=2ZUOE.3<'WWT07G_!P1>#XAC)F@6?"P,1'0O16I8\:7$6@S.F-E3>
M])\M6UCA!A$-U7>+ZN:]6BJ4S[U7)8&Q$0R+7*;:A2$S9[-@092@0K+!J'!G
M]EK#><-Y\\O<(\[G?IGBHH(2.',BDDBG)68^&<]2T:G6\8-/MN&\X?S;:.G-
M'7$W>)Z[(W2VP+T')H+3#)0/S!4164;I>;2I)"Z73SO_@M/A+%F<!IO_F@#:
M)[_VDVT)OOLGVQ)\]T^V)?CNGVQ+\-T_V9;@NW^R+<%W_V1;@N_^R;8$W_V3
M:W]R^ X][.FL6UWO\&1R@H->H>?Y)B4NU_(W7?=\O)7V-RDN91:69V<<&*Z=
M"\Y9A<D%+US*+2J\]'ZGO:>3G?["N4F9"X&!%>$+@Q"!H4DU3"Q<-K3*(L>-
M;;>IY*T/#EB^LRX;KN\6URTNO%PXW_W'.<Z+"19]<,QS0^@VFC,$T$P8G3*H
M*(4V=YW)VY#>D-XBP_>#]+E$-[24M(TS\R9'DNC2,MK0DD47%/<&DI6B(;TA
M_=OHZBTV?$>(?C:7W:8X@UHJ!C*'>K:7(!W=%)8@>>NX%LJIY=/1USXE_5G7
M,']\0.8HJ\<%_%6CMY:K_BV9+MJD@@XD][2%[&O^DY:\0"Q%:"RB]9M8"E+;
M670\!"P<>8I,!MZEL!E24U#7\\.D$<"M1+NQO8:G-3?8WAZVS>FPO!A?<#ID
MDZQQ)I$5 G;:5<8+DUF*J2ANK([E_V?O2YL:2Y)L_XJ,-SU6;4;0L2]58YA1
M129#VD@T663EB"]8K$A"($:"(M&O?QY7 HE]28$$1'=!"NGJWEC<3QSW\' 7
M)4RU:/K<-+TX'7Y*TR>K>=0<5-I3E(2KBFQXI!58+%9$$P2W+-%R\*1H^O.I
M>/$KS$AII_P*EFI04L50SDZ03XMQ!(P<EF>5="YRI9EUBT7!2V3)W*\L4S#W
M*V<4W#-:>^@*%8OL9=OIG53%1V?K6IM-;I]QR0-V?%&DZS*G1TG^,[,!>C?4
M*)_--$$2JU3D(FHKI,&.4*[ %G:1E=BIQ>=/S:NQ4]9C!ZPI2.H0QT$AR[5$
M)AA!M.9$1<!L0I>I$K--)#0#O7H;V=,*PA:$?6V$+0[EQ4+<*8>R\,X*@0GR
M/$>K4L*1DP3^U#H2@Q./V+]0/LH"N05R"^2^&<@MGOV?@MRI<$)#7')&(V$!
M:+F, AEC!8HR>)D 4)5)!7(+Y!;(?5N06^(ZYP.M4_LO&C.+'0"JHTHC'H1$
MSEN"DF?*,&V4=_3=^0\JY_6_JLJQJY/2M'?7C;^OFC#<L]2M+=552V-+W=K7
MJ%N['OVX;"VIRM;B#UQVLY2M+65K2]G:4K:VE*U]WY;W1S*L!59<Z^225H%[
M28V,CK#((K10PMN588T)9:0<([K%AMYM-^@VV,B;Y_7#)H6V\>:PVX:V<KA>
M;&U\[C0Z35)?_]*Y;D,W#C<9/*/;[&R>[W::P\9ZJ[/U?5,T.JUN<^> -[_7
M::/S[:Q^V+A:MM9AQ6QD FE*!.*12*2E3BAX;)V.DF+.LP5MWDH=GP)N!=S>
M-+A]J#WP5T.\284/FIC5))^8= 0C3IU'AB6%A-8Q<;#6J6<SB-DN>%?P[J/B
M7=F87E@<G%1 B9XX*DE$GI!<P-'F?%9&(X^YM &G8$6I3%O0L*#AR[*_=[XM
M_&K -BD% X#EC5$242<!V+0)R&*5$WD9GV+4G)B\*<Q^NA!,*4U;2M.^33#3
MSC*<L,<F>>Y2,"DR:;G"R@2J!7\<M2L':>:(>-.E:8WR!A-/$)4*Y]2D%AG)
M%/(,>\F%C"JJI56^;+A>H*/(1:L74JO+X8V%TO*)XXHK:Y2)$>&8DQ@"$T4N
M.;#?/'8N8(V%LB5#2-'SN>EY<<S\A)Y/'#-86&X2#B@ZFP_%4H<,C08%I8,)
M$;N42UD6/2]Z_A(LO?@C9J//$W\$LXYCZS!*3 ,[9RPB&YQ%/A#%2!*8$[YX
M[+QDJ9G[E64*YGYEF8*Y7UFF8.Y7EBF8^Y5E"N9^99F"N5]9IF#N5Y8IF/N5
MI33M+&-]'N5O^A#EK@1/FFDCC/6&LZA,P";X9*),U@9;=H47W^]TM32M)=%B
M)AG2CCO$4]3(.(R18EP;&9+TW&3/DY*SRHZP0#%\1:]GJ]=E7WBQ]'RZ2HS%
M*BE.$;/P"Z98(XV51%P:0YR2TDE5"E8632\[PV]3TR<KNM8^VI@+3BCI$3>!
M(RV%1LXZ$Y-E*7!6-+UH>MD;7FB-GDIA)F@4.E*+M- !<9X4,D%1E'R2@HO$
MB5Q CO[N0])+:=I%03K-8W#!&ZR=Y]PPJZ0!H)/,>D83U26GQ$* VI72M"DZ
MYHSV2/.$<VE:C#1-%B7J@L52XA#LTBI=H'"7HK8+H[;%Z;"X.C[E= @>6(M/
M$4F2*PDP19 5P6<=5S;$R$@,)4RU:/K<-+TX'7Y*TR>K.7,*DP FBA-:(C!(
M*+(^2*1BL)188[@H >E%TY]/Q8M?849*.^57<%QH)Q)',E@%2INKJG%O$#>:
MP@0FQW%:+ I>BG*6HIRO.PFEF,8,%@66+ V:&6D9YK 8N*0DY;G$!J'"*UFB
M1A9_Y=B>=MZ$J%7$4J&H142<AH@,PR8?1_0T -T+"58.LZPY?S<U-0K %H!]
M?P!;/&;S!]8ICYD)#(!4IUQQ,Q-QX9'QVB(J#0-#2FE/U,PSCQ90+:!:0/6%
M6&MQ6BX8V$Y8+([4^!SL+$R0B',OD=61HD@5%MKPF,)+I3<MD%L@MT#N8C@*
MBFMY1M!Z)62-*XZI!.**8TXW:)#1RB.9HDLR.(H]'3D(WG71S7'7&J>'H#K^
M0A/&?UX5?1J ^F,FI/*64ZJ,)5SK& B3CA&7]M:K@K/P?S2I/#L2;'L(;<FU
MKOZJREQMI>L2OGGT=QR<',:CD\'OYW]T[6#03M"-/-J;1W_TCJJQR$SC=]NU
M1S[^V8KQ9+"3[[ ##?R]V_,';U,'NO&_O\)[X=A1+AL[C38\XT=CX_-AX_#+
M06/CT_G6]T]GH \@SU_@Y]MY<^?S07,84F/=D\;9'K'<,PX&6*#*(HY)1$XK
MB30+,#N4&AGB4BT"4!S#1)ST3_,)S/NJJ4[+5.=T<-).YZ.WVD<!YN=72E=$
MM<Z^,E+3:L>A%6L)Y*@VJI>6RS'>L_U0<^<UD(Q*C."ZV@E\&X0)NC&(H38M
M5K6Q7-5&@E4[@UOF<H^IU^WVS@:U7^#;T)TNW&CPSU_?9VE:R5>84<^J'CJ'
MFJ1BA=,W4T U-Y8]ZK;OIX#JXQ3M0CT_<A'(/^/QR;BB+*XJRI(//!CW5]?]
MV#4Q_["#5LT>0=?SB_A_IVU8!C-G*I4Q2_F05S!^I=5!$0_&$M'<6J8]8\0P
M"U8!$4+BRO@=$_]G&[]9R->.0O[GTT3"+XV']?; =WN#TWY\'];O85/4Z>=6
M_KPQW#ULK']MUS>^M."YP]V=3[2QTQPV=^I@!7\:7K=^=SL'P^9W:/_.)FL<
M-G%C8_.L"?<'*Z);WVF21J?1J@_!"MZY7B]3*6NUL"@FZ\'V50YIE>LG.2Z-
MC$Q0XY96"5EFE+V5^B(%]0KJO0SJ)1&4,HX*'L#6)MII+G@4+BDLB%)J)BZ_
M@GHOA'J3T@-*6$]\RADE1$ \A(ATX!'!NY8IAP55>&E5+',YXY"@4E3I^4FT
MJO19(P]*.:JZX"3O>9L8?YSV^X!U!=>>@FO3A9,H-YSHQ//^!7"XZ TRPKE<
M"UA$JSRUD2RM&K%(8?)%:]\B22DJ_:(J/455&+/>$X6$R8?5!,7(VH!1C-R(
ME#2K<F'Q9:9_.M!N0<^^J!55CKZ4B)82T;+ ?*]$M,QYR3B?8H$B<<$H%<C$
MH!#7GB/-F452&<&=M=1COK1*Z#)5[R>@I>!JP=5%Q=6%8N0%5Y^&JU-4W)OD
MHDJ(*>7 NM9@70,!!Q/;.Q\\H\&*#Q@G^&8CR.[<0[\($+.N]W>LC7R.\8?O
MGH8<2&:/#FI@DL%TG8R^V4NU_W@:&D@3)+%*12ZBMD(:[ CEBF'I(IO9UNE;
MU_2?B8<\VTM:\: )09PY8$&@G<@Y!\H+;#92(35.H*V2RQNZ>A'>5\G&4V;V
M52+"/_K,LCT=O'),,*059HA;$9#Q DAN=#91H873<FE5X[N\G)?36P6-W@RY
MJN;]1O#1<@W,^^,(-_H[=L]7K@9^ODRL],643X5$7P1$Q_#[^1_PF-RS4]NM
MVY.\O)^OVY/XT4.AS^I@ BFEN8X)!6QUSA9#D77,( H RU,(>0K>=2BTO6"#
M"* %#0 L8%&[E*(<#>TGTE,['(M/"79^$_'#)=AYL8.=K^O5XWS [S6,M\0T
MEYCF1T9X9&TYVL_F5^\HULZC[==Z_5HW#DI8<PGP>R5/W<O;YO=[ZNJ7:\;W
M]DFK?;1U%)N@")?Q?V_=]AO[[X#&TT\_&IW/A_!\OK6SS7<WOK0;]'.KT6FU
MFCNM;KVS?[:U_J5[W7_7/-QFS9U/M/Y]]Z"YLR\:ZZV#YN$F:W[_1+<V/K>V
M-KZ=;ZVO\?KA7U=CG2/SRABPLU3.H\"#-DA;'Y'#@CD?DS<TO<R^R'O9]BA0
M^'&@< '2&Q0HG"T43K8R:(K&">N1<UID#ZE 3DB-J%7$)\*8&6UE*/-FD/ #
M!$"/Z;%-8-1,&/))"[JUW\K_QM%;)2SZ#9#$F[FVJM08CT7$M2P$ (@[H]G?
MR9.?P7%0T/%9Z'@EC!HG+>$'B:!PKF'FD-9$HUSFQ\$L*_@I!0(^@*;_;*K2
MHM%SU>BIT W"G*-:(\9S%+4-'FD2'(K14>JTIHFKI56!%TB9'^ S%QLGT-AX
MO_XOWI6E:XO3X-*U#WE<X8']X84[LG"W_?B!W$\_-S3OAI4M@)/^W873O@XG
M:TP?4Y!4,)/ RN+8>,13Q,@2QY!(7B?A8 [#JQY3>*0>O0U/?4'1@J(+[]\O
M*/I<%)U8MF#6FN (0X":%'&B-'*8.F1XLI(SQ3'SKW@HX85!]#T?1P 5J4X=
MC/SX.0;Y"*ZI'<(76X-:A!:&NX*5+^*31S47:ONV?32H/NCV!H,<$'IT;V[<
M*NKSJ'>2X]6@[;:[4OOZW'M9N%4_^BP%(0?R;$&7^O#"]P[C<NTHGBP_D'[W
MSQ/X9V2%]%)ML_KB2BV'N/K>X"2_-_4T^!H\)1_*R/?IC6Z<H[1SSFC4SI-Z
MF3VZ=AA/6KVP\O@HUH46ESPBQWT W?YYK><ZH\#T/#R]T_Z4+5<[[O5/$HQN
M+X_320_F&*8/?FH#F^+)>?X&W.;(MX]M=QE>GN:NU;KQ[]BM9J#;_K_3=LC!
MP5D(+(# \2BT=W))OSTX6*EM77]NM^W/X>N'[>I$S>TB<W[%[(3F>5#_W+J3
M\^-1)'. A:)Z-"A"/(?FYS1 \*W!2?]T]*WV8' *L^_.JW?;)Z=5%MG:6?ND
M-75WM-^W 82H'Z$SM3Z(Q-'^8+FZ,_Q]W+4>GI>;""@RND$6F4OO[.B@4.\H
MAQ3V1_($#[2@$B<UGX/R1W?*3>FOU*[*6(:HO/:VCTZK;UZ1NO&D<CKR&QSW
M!NU\S:_]V+5Y2B<!SO^X&J,^EE,\^8IUH ^G)W=_Y5X)'P=++HR $WIM%*=^
MM_J3Z,_]B!Q WP&J]D5_M=TS>SY8^M?5CD.OKPWTL\;H0118_2_7AT??TO!K
M,C"B.9KHO$@#!1.P8!.B@Q=<I!!8\I)K]4#37FYFJCO^VCZ!;OM'S%5.5 >Z
M?$O.B[<-LM]CK17S$C,%4@!.\7IW1V #4AB@#0!9((@@<A5,3A_,^.48B%+;
MPR4G&8S"U!W^^=1CA(XZ;6+@T6'#O0 &+XTDFBEFC%/>SL0+,IK7"4___'>C
M_=:Y^K//%M6!SV^M[>&@ N7:(:620#PJA722"5EF8'%+1DN?#Q9B/;N#A193
M19RD%#/';7(N)GB4Y))81BWA,['5REQ?G6O1V-XC8#V!HF$DP,I"7(F @ %)
ME%341@9I#'9+JURI>^;Z)TX9+M?.6FW?JD@U4+1\ 'F*5,/C_"B]UHB'#)Y4
MV&*E=M7@>+R= 20>A/6:M0$]O1O<1A;&4R1>>).$8"#CVG.NC698*F.$4#BE
MQ/'XU*2Z<FIRIJ)_M6!HKF/W@97!GS76]GS4 @<AD;$LITYE EDB<#Y>&1)G
M+"9+@+:QNQP-ST4_Q6,(5"FLA.,N8H>9I5I''KB23-%*%O"%+. B"R\L"S_J
MVWNP '(JA4!&Y#/8-!^_%C&@0(*A4; ("U9>!.\7A6MGJB\1Z8F.C]< I&<=
MXRY"^%)"N#\$0,(6"*]R 9F<\Y1[@I%AWB+%X9,(4R1U $#"=R5Q?BX@B:@Y
MX]&$X!.L_=)&CADEG@>2/%%^#$BD -+KR *I[^_I7'-:\82XY;D8=3[< V0!
M11>"2-IBXPT T@-KTW5 NM<-FJ,F*G)W#\ZDGW/JWN*:?<>6]2(FTKFN??DD
M2N\46E"9^NM3EOYEF.;:8<X-]'$5LK/V Q024\>E318E'2+B.!$$5-XB4%+@
M;)A*;OW2*A4W-7*Q\^\4@7B.0&P!993>&!\%<D[DH \LD<-)(J^$P4;+P)@&
M@< WZ\Q<"L2=KC>8@(>];^_/$A^M2N$TYIV3T^,SVP\U&S+6CP&U:L4@OF%3
M_!'J]:WJ^+_[;1_7+CN_=G1T:KL?7/,:PZ9H=+[Q^L[V66.]SD$+ Z<Z,.61
M]<D!9TX1F:@93!T7W-@@H^5+JV;6E'F^-GP1HID)T7:&<H,CCRIP1"R%M=T(
ME3,,)Y1P4I@JGX12HPV\5[#^7P4$YVO^%_G]"?G=6M_$C4Y]V!ANGF^M?Z(@
MOQ+81K0"C$4M*.+<2&0%\!%L@G$N C )D^77O"O'09&BV:'@66-_+T0BC<0&
MJ9!14.<D@S"7*%IC)%@=L)JQ3&B?AH+KO;.CQV/8U:BMM:FO5!]?QD7U'-CI
M?U>4^#C/;G95' U&[1D\P:>P:!$'HYBNV\^N/-)!\DK>D"?V[_?8WHA'<;GV
M/R<O'K)VYSG&UW(&K=UAF8'5%6LM"[H $GQV%/N#5OOX,I:LRG-Y?-SO_6AG
M%0#3[TXH!J2$^UY#8ZV=Q39K:TQ<.ZP%T98PD8RG@L5TN_^(W0ZS]4H0)YE:
MMRZ:^^_8SY%5=G]R?!?1#P:>6SFB>:<)P-F$]JV1^MD>X]SIA$'BB!2(.Y.0
M<S2AF%PR(@:.N<S@N7+3'?"/;%U?T8_:+^,__WEAI[<',S?3+^(?\S(('V;/
M+FA,'''6> 6.LF".+FP?[:_4OL>:/>SU3T CJHM#.R60X'QK%T_.8ARU8N*K
MR#>XZ>BP'M[JQU U)$=Y@NCGZ$X8$VAN;=#*S@GX9KZ7M_W^>8ZSO+Q??K=J
M;[=Z/^^9C0<!/AP/7ZWW][@_IX.83KNU+BQ*@XMOCR\_:=D3(-U_QQSW69'N
MD]8H!!=^3[J68W;AC7''1S%O%PV_TE10Y=/NJ!F]XSB*K;S2J.L^EPLTG(?;
M^D8X\VV-F3N>/B?&NDHH\W^GMG]2=1!&O9^3#UPHE(O[]NCBMB"4<./+J^$>
MF:Y>#WM]LWL3ZZ,\.T_?MUF^0_>RS(_U>2I"^LP.QB1O%+U\13/&PE\E&5&_
M#2I]S5M/3PX35$%Q3+D37'%AO/&8,Z5UH-+!G<DCO'<#F"1X]23;8R13>6/R
M<[]W>/L2^7'W+*>,B1^-]4\_MM;V(A .[IQ&FDF%> 2+PBF?D!$B4,.<C"Z7
M[KP95/AS%BFGPL4@ W5"<4VLL\)3Y2/GB1/*^"/\&D4\7E@\AB >7.H$O!0C
M&PW8FC%I9,".1SX!3W) 9)EQ2ZODSB*0MQJ;H],/5U;H\9I\?3&? ^H\0IJJ
M]#JW"\_:5*>VTOIE1WX?\:T_QA ]<FJL'85OE\QH=+\B>V-HJJ_M64%RL:J$
MK%4<Y>,*R&HND?5,!&(H51@OK?)9;QG, )J*#"V$##5 AL"XYD8#=#EB1BG5
MG# &$<JC<9AC8W+L*'U@?;OA+)LI4P-:#YQW,&)C;PKN_FC9H_VX>2F3E3.W
MLE6*$(Z$,#MLHV0IN4 1E;"2<N!4R'% ,Y4L=LD#Q$F:%]'W!F1%.AZ4COK^
M7C*"$A8P$M8# [<8(V,=09IS0V4T.-BTM"INU@N[EV$EX+<5UK0/C^'Z*\Z6
M2X_F%6<\V..U?%3^I+I;>#["G4TCVBUP]RY KDAP)<&;I'&V)['1BEH'JZJV
M.1!6("=51,H1 :8ECC"!3\H1LIC(5:9\,N4A"I*PHDBI"+PJP;IF,"QIVE&I
M!"&!ZGAK8LN':^/9L6?VPH%U?-KW+<"2RKL]QB?;'7FLLJW8!]#KGH\ ;PQQ
M*[6[=W9N :0,;5>=X-=R&4S\_K63G,8N/FTA?MZ&#]+/V'6_VYEA/IC07MG[
MZ=1_-'(,&@Z$!C !I/2(RZ"0T]PC1Q43@&%Y5I96Z<HMIRK=,SG8'*=^^[1W
M$D.]REMQ%;\^N"B<@UW(!156*(^4S84:J;'(.<F1P!H'K%4P/"RMRI6;D3@7
MHG#=)+QW+]G%;CO^'9_DII\"G?:@EDZ[ '(YP\W?L9_C*=[0@8PGAB TXNEA
MKV]S[IV^/8ZG)VT_6,Z[16^HR_=VL+9U=)>@3/9:?R+ @'!+@A%,)VS!AM!:
MY,@@20CUS%![1XJ&$F#PT^8<KV_O>1,L9\P@;U5"W$>-8/0U\DJ):(F*(MA\
M_N06:/G';<$F  -W*T3ME_%G_UP&WG3<;_\]DI?JB)/O@>EWE&W!7O])B];S
MY.=948(W?)_[^_VX#YWXHS<H07]CL:*-_3TA8A $>V2("(@'(I%5%@PM%D*@
M/#I'11:KF]SEFIO@Q>)4JLW_^,-7IE,E<_9IIZ@\LV#B,9ZDX]CQ'.E,A,7&
M84F4=F.C#Z1N%J'._[;G%3_>Z:V-(+=L!MX/;<"??0+C#J8$>8Q!!C&0:)N=
MZ13>YRE&8GG,YYX?B#P%!C1HU8Y'$_#TPW:O*B8-4 EH[5;_W[9_,OZC$IA1
MZK,I01F+42!%8L82L[6]QVBT*>>Q@64#)"9Z"8!E&++4.&U 7ES (#$/H59&
MEJ/1X&=A&+3#.%YKG(FP75'C;@5*)SW@RB>G_1PMU/^[[>, N'DW1Z#OM^Y@
MVL"T_H9;#FJGXX1:5=09\/Q\'=PO_@"JDV/.<LA!E=>QHN<)Z'NU1YV#U\;K
M\#AR%*A^[()M,': 3CL7CJMVPUW'D7H54M[:KI7:M\LXOQMW6*Z-@/82HZ\Z
M,"K/[Z2'%]DQH?G#JDVCTEW1]H]R.D)XX7,:L2JJ#RR38^"UO5 %$$Y;+C>[
MX3)#Z<>4^SH8!23"_/0.@:#<$OLWY6Y^2S%;3S1?_B=GGH1!/@;$&+.YN]/2
M+;*9<G%4OGNS0S]S?-XS3:5VF'/LN6#4".FT#))'AIW1>C9I]+M GX^J1)83
MC/ZPR%SO;)-\?"YA8(HR(2_ST7B6%'+$<,2=\BQIHAVE2ZOBEJVF9Q^-U]PJ
M+7W@P1C.=-0B19]/'GEE=&(SRO9=)OOJ9&># 4<?12(1$2X$@A^#G/ >$4^D
MC=J9E#,E<7/?9"_LP?6=ZE#2% @M3S&!J74OP>I3=0)6NNXY(+D%T\2U>R?1
MMXX 1O?/QU9R.^:<O/UX+=#>G0,GN-@'O2?6?A30!E\_C'9PVA]%<HR^^4#
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M<OAZ=SC<=[LAX4P,RYN[:70KRO!T'9._S>*9R*AL5,QIG4 FXZ2RU#,.I>R
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MP:I;7?;Z]Z2X^J9UL LX6$EO-J!?E+7]975I>^&CEU08G'@(#U))S_R*>3:
M+1;MRD+W+^+QZ9G'O^$R>-3JD><?[?(2B9?7P+NL3.<,5>T66YJ?M]P@7=V"
M>L9'OG*M/\>I6RV<H#@F-UPT+W*2ZOJZZ_J:1=?.J[$,SMXC5:G]HSL8CEK_
MV7>#T=WZW+Z8]E?#!F'G\WJSA. RS4$;X%K91',"9YF.4ICDSCOHXEPI7WEI
M+.S48X_C+)IQ,M;GR0@68QOPMI[[I')O^ZC]]2-T=MJL<_0%O7;\SNH[Z*Q_
MP/&].UQ;W8#V^PW:^7I)Y=ZC]L_-U>]\X^B+Z*Q_ZJ&W_Z.]_IVUM[>VVOC]
MSO;W@\WMCVRC5.[M3JKV?J8'WX*3CB5A2=*E;J\WCABJ+=%"4YXR<(BQG&BZ
M6.7O=HTX%Z:V^2_:T-POQ)]PZ?*9G_^)JK:+B0YWU6L7^O)<I]?^+)U7JUJ;
M3:T=G:@UYX!G:S1A-$@"C!OB->>$\908MRJG9)96S"7E69ZW6JLLYJ8L1@LP
MD0HK8F!@$K4N:OPU @O S62;@1ZCG586\_!P9R=PSV #D\(1CZ(BX+(@-DH@
M3(OL!$TE':E4I[Y8F_9YP[VRF,IBYJS7*HNY;[4F3M2:348:SX"8G )!N97N
M"C&3(+D'G< R*I=6K'@R:FU.S0@7-X3T.2'8XIUB2)<\\K,D6)G+E(TR*40.
MU E<YTHGI11PJYDXSN. 8W=*G4L@KP3KGC71X728* @-0:O2]",BP2HZ"5U>
MD@1Z5.@2^^!T*?X_K]Y."]3E[J6"]I(6EW=$[&Q'/BJOF#.:3Z,CRDNJ='2$
MZR0(4&6(2>7PH7>*9@U&6KNTPEY)>[$;0,7S$\7SI48X\9B\-#S3J"'S["*5
M/E%?BAG*+,/$&X!C;Z :X0>'[6F4PWN4E5"1&&<S 8;FV"DNB10Y&6ME9- 4
MG[S8HZ6"]HF"]J(1OBMBJ_]^WX ]]=^E8-92#X3YTC;":D&<MHDXJ4PT5B7M
M_=**G%MGZ4=QT9]:EL?Z5G=P-P_]DB=^ZGKF4G(@@\U2"J? ! !CC4#6B'9&
M:HJK#7Y5NK&2@WO6-9VW4QXZ $\NQ4"H2)1 TJ4=JP!22I(K'736W#0-.N<4
M*UR@78Z7"MJ+Y."NB*T>^J.B><I#!XB"94I0>$! ZX#,(2@2'<]<H$A]:;?+
M7E%E*YZ?"YXOST. %"/7FFI9CH!23X7CQB2(H)70?,+W]3'?KT;XP6%[ZJ%+
M+:7*:(1!Z%)@(7KBG,PDTR0XU:4VCVCJPU?0/A?07K+#?D?$5@_]O@%[ZJ$;
M*QD $^->#L!H(#9[14S*M$13D%4C8+6\<QQ\CH"=TR9Z<V\]+O.QN,YZ?^1Z
M%TYF7WVFYP;AP4F2P^3 M,")B/W]<ORZ/,W5*1#/2FE=RC1N55BA,HV'4UR?
MI]Q]6]JE^R (JJFFW)<N50"1;G@?N52*Q50<!+BDEM/M8HOS@,TC;R(\FF9X
MPHF2\YR:)ZHL+REY>4=-6<,LCZI%3\,LTJEL/ ?B$E@"P;A)7V_C5*0"C L,
M_;57DL]K3_49J-%*MN:QMY(,"$@VQI!!:X4+D K.2O'>')@.Y].P*]EZ<#4Q
M=;R$)XV,BA+O8BF(Q1FQS@C"HJ0T:,T]E#SLY3O'8I^/DJA<JW*M^6QIW5%1
M5J[UJ$IT*M3&4DB".P(B%J[E%'&EPZ2+.I7^H$:DTC;]%=?/@6LU0;I_-"7Z
MIJLB3Y<-?;*U$S_LMMH. 3+I4U-J)_[>=X.F_]=J=Y#"J#\8MKJ[89 *AIHR
MT9/*\FY_M-4?X+WB#0HOELYF[K1KF^O-U)? >W"1ZM*2CH(#YJ*4+"2=K,[:
MG70O49?4%;^]PIA4$WUS\ICC-@5L45K</'AIT?;VQL$WK;@(UB%A2HP2H"D1
MX[TF/IK$T=62EMFR+0;7M[A9;KUI&MQ]3GNC5"K)GS1+.M8,TVBX4BT\%$Q>
MS;1<LXS*1L6<U@G0Z#FI+/6,@Q94^23FTH'I\M7Z*>VX[BYJO--E>_J9NH #
M_<8$TX FB\1<MHD"Y<3Z+ E#V2@1M5 ^E,SKBPY :ZK?.RJ_RQ;J0ZW'1K3C
MHM2#1N*E]>1?KMMKBL_^6ATOMYY)%S:T7VMHHXH"&5NP8J >RH+!LCQ>$W?K
M:K<P%;U7NW]U4:AQ^'R6QS_W>X>3M7'*=)KV2*M(8G<F*X=>N7)0_?9<:=SG
MCA.-\7K!#;=:<3)9Y?/7F@?T.9JPS?EN*0IM:&212Q/!0W;9!G2+G.7>2">.
M,_S$%46(^'F+\+:_L]/?;>S"B1R/;[TZ>8H3W4]?FNY??R/7UK_\;*]OH$_T
MXZC]YIN(2H:@!#$6$@%.'5H"R*0Y%"FR!2OL]?[M%8(-(?N@K.161TC*&YV<
MXDAA/7."@9T(UEZQIS"38-_B2BP]L*M@3P4K<\P")4LX5YE -)XX2)Y$EYS.
M3N40Z*T$ZQ6S6K 4HY; <C)2&1<BL]%1B8QO(EAUQ:G9*M@["E8!U0)<(#XQ
M0T!E0ZS-D629$JBH5$CI5H)]2%5<!7M1L(C*R(, 0I75!#RUQ)F V,V&:XU2
M1P_P5H*56C*CI$PY>XA)^ACP-RVL"D;&H,]GT>MJ8^<JV$"#DU128H(/!$"@
M8%F41'FI8C*!HQ=V*\%&%T5TWO)DBD:P)EEK\*HF18@ZCFTL118XCB4S7@4[
M5\&F0$63%!TA Y*G""A8Q*X*.HE -0?A2^O22R+ ]_)":P^)?+,]^ZIUL-5%
MGG^0!NB\H:(MS0]/XTQC5Z#ISWWB"4R'0">],KM_I=[A<NNF_N7]>0DT,Y<E
M]R+$ -(KZZ(Q#/F&8,A$U#@%F3$ZT6!HF^I"G]="I\5+R-Q$@0:)J:+!8E3(
M.:PER5M@!@U&$O%6&LQZ:GS@3DB'&&*HRE#2-@@>I5")3DP3:C!#CG^IG&..
M@H5 58HTDJ@H1<X!AA@5&$%RX#55W#MS8PUVB?;I]GHM/U% N"!.@@UF'.9^
M)@&C-R'L[^SW2OO>5A]UXP#7^,[>(&VEW>&XSRS^G5I_Z_6'P[\_1%^XD_!X
MV$IQOY?6\M00U\H(WTX/\$,SOG_AZ%YZU[BC;RZ!R0+)&046"1@;B1'H.].8
MJ,VHF&S,SZ=KW#H:\K)6^[LXE&8O:J:UW/K;F[6W'_X^9ADOK7.<7)9"S[UE
MF%FVYG97??CV9G6L=:PX5BL?I,/=C;J@+5[GH3_Z _QSM^D0'?8'@[0;#IL_
M1@.\:*_9OYQOPZLG-3V%E(^3(C*:CF9BD+-\OU&;J^<Z)V^.-[%)[@_($'V5
M9EZ&"==/=]1]T7/3L-<7_/R%<+VL+F:_NY[;#0V_+-&F8Q=2L,:'I/=7(O^9
M96,_LQ8!?YNE@H&FGAJAF2C9UE$ZGU76R=!@< D%V>2B70B/EU3K(3XG_G9I
MWME6OX<S.7SWG_WNZ/"9Y%'_@+6O'\3&]M;6VM>/AYW5CWQC^\_NQOH'NO$5
MQ_RU_;/]_N-/])IWSN=1KZU_EQO;L8OCDGA-VEG=[':^_G.KO?UI:_/]1[EQ
M].Y@<_6/K;7WF[D]??*76<V-LI)$]+L)"$6)B]X1Y,">BN!8,')I1=.+N6A_
MO[>U7]N<5!VV8#HL*,-0@X$#&R"QY#T+.BNF&$00TE4=]N Z;*J\678^EB+&
MJ+(8@90L<58W2;7 6$B.1;>TPM7%QB95AU4=]J1UV PJS" :LK<Y2(\J+$LO
M!0*#._ \^L3A:A56-==\-=?I46!NO$I<1Z(2=02L<,1ESX@2QEMAI$5!+:W<
MN:!S55Y5>2V@\IJ%@&7#>=2N2;4"IX)/SJ2@ 5BR-HMKM%<E8/>DQJ8.XT9.
M#3.2:.?TN%JEH:4,'G#'A0A965'*1U7^5578RU5A+CGK F=6 (=HF<E49)^E
M2EE0H7A580^NPN2I#ZFT39%*PDVD!)1,Q"J:B9)<<.3)(7BUM&+-Q99TBZ?#
M?K$I<9R^@0^1KE=[]9/W_\F75']ULAO?.MZ);TWMPK=<+ E:.R45ZH5U.ITM
M$ G4VT25-!EDC.B\,Z.42S;0B#KL?%[B)0V7K[ F5V4F3H3V=B*S]2*R\3C?
M[,;U4P&^.9%?)XW6\KK[^>_^H'EC-!IT_7Z3)K;>_[?#RXRJH9K%4$WW3@47
M!)..$ATI)^ #$,N2(I"B#(J+R'FI?G&7_9K:L.V!%<#__3^&,_Y;[:M7Q53%
M5,7T,L0T"^LQN9RO5BER2\%*ZGQ,(BF;N#7.&%-9S[-D/:?N>9"9,@!TSYEG
M!**FQ'(AB:8T*&,0%SPL#NN94U;@D_#IONP.$HZA5##Z[KJ[M_/=GFXGG]L9
MF]IP:7'WR87BSH**VH@(2DO'I- E:BMD8BE<./EWB:TY9V)"]_>4T9Y\*F>;
MA\-NQEDIHQB.7T:;48W%'8W%F7:'3#G+,D?Y!%':,$E)O*&)9.:8DMP(&^/2
M"J-W;F928;S , 9+'3 =A%*0'#<Q&Z4#]=(K\/8F@;+I4IBY^S-%<I0&_0KO
M1X'W5-),-E)(R,0Q)(2@32 >C"$^Z!BHH10B/3',%>+/%^*0*8A,N57. W71
M^XAC2\(QZPU7HD+\:4%\*J&$HI5V#B%N%! (49%2A8$D:K4U8&,PKD+\!4!\
M#H&?"N5'@/)IY":5SJ<.;72.$<FX5YQX'Q#*T0O4UR9JYA>-C+^D/?GS.)C>
MAV^-^I.2(R]L1[YN(3P),3UF5.<\;OX8]'?>]$-WO&,P&C?YJ39E;C9E^L"7
M8,PJ;1EA5-I2A%<0YZPO-@4X4,U *[0IXN*!KXKHYX/HAPKP5*0_--)/8SU)
ME=J7N1Q*-Q(=01^(XS22E(R/-D!.)L[-$:QHKS2KBFFQ_/6J?!]:^9ZZ[M[Z
MY*G)A-I"LZA/Q 9)B2A="614CMJX:#3K):5>7%^-ZWG&#FN^1153%5,5TXL2
MT\/NB8X)F-O!I[ZN6GGSWFGZJS_F8)5OS<*WNE.[GA)YE@]*DVAXZ6DM#3$\
M).(]]<IRFJWU\ZL&4N&[@/"=F_]4X?M \#UUE[@7B%\;"2@  HP'XH5+!#'-
M/8N)N\07"[XO:9]SO/);(_?SF@K.+SY^,X?CQ3=,J;JV#\IUAVA8U5"S:*CI
ML\/&1^ F9:)L28RVJ)R,T8+(8ETXRTJ58J\UFOXT83[+@;HY;(?/>*"N GON
MP#[=$"_M^8)CG*@L2\O2K(EQ5!/E TT&G$B,+:W(B]RC%@586#@OXE9X!?>#
M@?MT#]R#\T(D1TR.IM34R\1G R0)2JT4W$C+JM5^JC"O>^!/0DR+7:V@ZM^Y
MZ]_3N XD#UR$0(02Y3!* N*DDX3%8+VA1M.2;;@HY.I!.Q(U/24? XYGVQ*-
MFV=/>A*QLQTO;Q-COK)"XW/77")XK@)CRIG2/1WU5[0,+RL]UY1%W90HG45A
MU1*E=])#:V^GHS?)BAAR1AY(2[][5$&6:4V"<&A*DF!1H![2</$DS?Q*E#[5
M7:,7BVCF@X$0I8.H@>MLDJ.*BBP#9'0K5$7T@R/Z-&PCM6,9_70BK!$$LBI[
MO4$3);)P@@9FE$-$WV??F@KH!0#T+'CF45.;8HH9(!ICJ762.P&1>05*7HWG
M"N/YPO@T0!.=%B+K1("JDK?A./'!*L*<=\(*%U*>8]Y&A?(B0WFV39@H#!-6
M!N?!..&H$R:Z$+GPU,I8;?.#@_HT&4O[+)(6GM#(& $D4,1PA'?6,>F --RX
MDLU1;7,%] F@*1IG,(ACPQDH'QP2/+ T!*? ,D8KH!\<T%,=/JP4C-M G$\&
MR;:)Q#@IB X<0.(BBM8LK9A+3K,L&*)K>X\G],F7E&+W$.T]GI5MF:F)>E!1
M,DX5"%#:^N"SXEJJ' -'QV^RIP3'>TI*T%\40JJ%KQ?4:K77WXQ.>K2_^::I
M#%9G2X(JI:^M%L2IF(A7SK@D6%!*7]I<[W9;RHO!1N>XV?RL-,:=L@6J:*MH
MJVBK:*MH'^=LA8!H #U$EQ@8S7%-,$-#AJ@#R\%6"O>L*-S:*85S&E*(RA 5
M<]FYUXDX:RQQ0ODL9+02\I.A<"^IPL94<Y->?SB\Y<FQIWMRM=8'>!)BFJF!
M*#<A1ZL42 ]!!Y>BA,1,Y)(R8.X&5NBJY-1:6OD!# L:E,.IV$#@S'!'8N("
M#0MCQ$CI2&8B&I>#R0D-B[A+:FH%\^(R2B:X-S)EQJ4$9:VG.@J$,=,R9^04
M-\!R;8"P2-#N3'%&E&+PS!*1LR?@/!"7G"-.4Y.,SYIR55L@O "09VJ5=<ZD
M# PL-=:HI*+W3#":-(4*\J<&\E/[S76(ECE-I&>1@%69>"$8T=HX-.!*.C._
MHWT5Y(M,R^\>'*JT_%%A/17OB4[$)*TD)FJTW2PGXKFBQ'#P5M D8O"+0\M?
M4HI"[792CR _53$M1I2G%N1^8,OR83K@XXVQP&TD+-A,0#%!?,J&.%!.^11I
MX'%IA=_E"&#%]>+Z@@\6\*DH?W"43\5^A-"1YLB(C$D3R$D0&X0CPB"-S$$C
MA[2UXLM3Q7NE6T]"3(OAO5=%_."*>,J1UUEZS9@DECI%@!I%O.>49$Z%\E99
MKM/BT*V7E)E1>Y_4L&\54Q53%=,S%],L-&P.6Z7G:%AMH_ PK*L]O2LJE4XV
M A"6C"'@-2761D6<A9AY3#&$>%D]C9K4]"Q0/']GJJ+XH5 \Y3L990P#$(1E
M!P2BC,3Y[(D47%#E#57)+0R*7](>:.V$\D 'KFM-]<523Q^GCU7GI RUPI$8
M(!,P0A'O7"1<HIRC4<$[6F/L+P#H<]@JKX!^-$"?>@TT&0F0%6%:<^0;UA&'
MOB!!-@E1995R .0;=R[#5[&\N%A^N ,1%>,/AO&IC7'%J<^1,P).H-&6AA,'
MF9,H5"P-ZH)5N1KMIPKTNC'^),2TB"4/JMZ=O]Z=+F"@,I,T:B)C+,X2X\0K
M8(19"UIY ;*I<+Q(W.HE]D'YY_YN:@E:VZ#<,0+MI-<B!\\9NH2992^SAA"
M.A>48WQ2Q_7F63RUCNL=M=&7,Z&;2&W0H(F20 FDQ(AC 562C%P!N@"N5,33
MXF(]E06KY%IK,S_@WC!PF9-$[X&7;43K3*19"1LD%3HA%:F8?GA,3QUL<%)R
M[RTR#('N78B.&*&!6*U#H"P"SZ7*)9_#?E'%]")C>@9(1X-V66KCA ]@@S,V
M"R5B0)1[P9V[&M(5R7-&\E2,AD;*@S*>E&Z7Y8B2)3Y13;CQSB*6J<^7[OO6
M;BC/#\PS-4_(T>,:$;A@) A7=ER%9]HS7#..1Z@&^A%@/55J"EF2]9F7[15-
MH"3%&YT%B3YR"2Q9&=FE-0RK?7ZQD+:1:EMVTZE.()WQ-#GMP6<9'$-@5T@_
M/*2GHGI,*<,-]<1D)PF(4"K+9TJ89+88:Z%97EHQ:N$;BKZD[*W:9.,>%5;*
M5&3*50+K "PS3H*3EH)D)9%<3/8K]/%^A;UY%9Y:JWEAE>+&='!1JA @!$N,
M2I& -IHX*C3Q/BF/G@UU)BZM"'GW(W^+P7/FN)?YK-1&K=E?15M%6T5;1;L@
MHIW)\3202IU<'IP%*[FC6C/#DL"79-2F\KCGR>.FG%OIN81@!2G;]@12CL2(
ME$GF/.0H@D+Q/P4>]Y**.DRUV_CNNKO#UM_&73<NB.29GY:L1].?A)AF,D@I
M2^LY2*9 J>1S$%$+9XU ,Q7R#0Q2K>K[\!8E3*<H,".02WA#E.:<@(QH412G
MQ(/3U$50N(R75IBJ=;J?&(YG89::66,$ ^8- T.M$^"#IBDBNY3"T3LPRXKH
M!T'T5*H"-T99-+4D1,<(:(C$EP3G1*F1VI?D9K,P1]0KEN=LDT$Z)G7ILB(1
MST$:!4G8B-XB=U;F< ,HU\8:"X7L4UNMI%=HE26"6I3#H%$3+X)!6PU<\9Q]
MB/,[*%9!OK@@GT,DJ(+Y,< \%<I12I6]6"#**S335@"QS*.9!FH-92'I6$X?
M70SE/!Z.7U)&0NVI4<^R/E4Q/68(IY9V?F"C\OU,ZU0=K-<)B!#@"&3\Q\0D
MB0I.&<MMR% .G%"[0&=:*Z;G7>3K[M&<VD]C0;$^%>>QD2?$NB+E:"A!A\ 2
MF[D@@FI/N;?.15'+ACQ5O%>J]23$])A.>U6_#ZY^I_QWKR$Z[3QAUAD"+,H2
MC O$&9%4]@)BA$6C6B\I[:+VTJB1WBJF*J8JIF<NIED2'>:P.UJK\#\*]_HQ
MO1%*A;:X7BUA(2+W,M$3[W4F@<6@/ ,-.2VMB)KB\#Q1//]$^(KBAT+Q="^-
MQ*-Q#(7D#2<0)!"C@B;)\LA4,"XFN3 H?DE[G[67Q@,=JZYEN1=*/6V_F3XS
MS:*SV@(GP2I!@$9+7'""H$;Q.5HG@XTUOOY4@3X;W[CS)OF,!^\JM.\!VJ?^
M Z#_H+FV)&F!_@/EE!CN#+'1*2=RL$F:I15^\=##HW1 KH!^JAOD%=X/!^^I
MG7%#F>+2&"(-TP0@:^*YS>AB."E82BQD6RWW4P5ZW1E_$F):[,H&50//7P-/
MA78X<!0?*E]!?220DR+H&DM"778R9\8C58M#L%YB5XW/:6^4=GP:_**UQ@UK
M((XG]+5 "<3^/L*H=?Q 5Q:2N%'%ELOF\5'5VG_=LDCD/";H^2C\E&*2&I2G
M44&.WI>2YY9%%P)-V<9)#=6;Z_E:0_6.ZOO=F5XDW.E0DL=E%JB^A78$370D
M-.D<$KK(,<:E%:TNYC;=MH;J'.#QR/MS55%613E_1:DT=TP'03-0B*6[<SG&
M[Y/U"A2<=(.HBO(A%>5I(#$!R[RTD&.:9@(0#;'<:&(<  ]1231RR'-YU9-5
M3U8]>8^Y]4I1;YC()JF"0J^4BX(Q(X7)7)NKU>3- KE5:]Y9:T[%9TLA_A@H
MD)S!$W")$4^I)3%3J[4,RI7ME_G6L:CZL^K/%Z8_9^&9')SEFGL6$@!2&.>D
M5]YQ)P+H9'/EF8^@,:<VK',2C@(CU-)$0 E'<!TJ],]MSMG9:$O=5Z8KSZQZ
MLNK)>]23P2B:!1-<"P,N4I-E]%E%:4/T6HFJ)Q]>3T[M.^D(W$$0A((1!#PM
MKKCSQ.; N9!@H^=+*X;.K_G3(RK*9MOJ'\VFY<FNS?BI.OL["(4P_KNLW^[N
M?G-$N-E^.GZT'3?XWMT]?@*#6)F\4H:LSZJSDOC>S8?CE[J[,>V.7G.^+!N5
M.YXX/_C'RMD]I*E[30 '?)SZO-<?=LMX7@]2J2#_5_KMH!M'6\>.W]07)Z.C
MIU]Q'J=R?W3U5RX^U]2#!!QY&ES]' ^H?'@9.#/G]MVF_MT:'(]FSWU/Q ^2
M^T%<QO&_=KT#=SA<^L?9!\>G/C?1MYJC6PE[_.^Y]3968$GDZ,!$DY($=.XL
M,QY\TD8+_)69$U=_LF[/4=,8A:5"*AT<<*ZM8V!,BDPH+Y@_SKYD9Y(#KC\I
MO[8_6LMO0MC?V<?EE^)560+K34( CN3W'FKIIZF.>^E_/QUN?HU[GH/J['SD
M.+;MSNH[NKD>?G96MWJ=G3^VVJAJV^MQ!]7Q=F<[_FAOQ[RVWF;?$K,:IQJ]
M]. U@9@#03,'Q*$@@]6!AH0F,J'%VL/Y'@WVTZ_6V1UTS$-C\T(QQ%9_?U0V
MS]^LO?W0<KNQU=T=]5O)#791EP]?E:)PO?VBUUN-7DMQ4B:N'*5HI9][N+82
M?NP@#9IM^-SO]?H'P];?NKLM''ZOW.+OKZ_4H1?F$J>ET?ZGNK*Q.#@]/;<W
M3*^/?_DM=H=[/7?XNKO;/&3SI=_.7JXHB_/Y"D4.X[=/]<@R'>N22;K$Y,Z3
MMY>;M\Y9T/%[PBXS"E>^39?9+=^3XNJ;7O?-ZP;+8%F"J(.=_V"Y7.;\9I?]
M15;.+]/J9OBHO?#12SRZ"7-X$,_%G--/^E+'97UKD%)K!S^W-6PE5)CQ;%K/
ME6>WYC>+-Q32HSK(-YO,8O[[NTUYSXF&G^_TS>(.+/:R.Y,L=L<'?FD31^\'
MDT_B\=_V"Z<;HI;"WQHQ%HK4N!*?1_CKSC'X)N=/D7./:=>9.;MMLN9ME]'"
M!?+>NN%6*R-Q;&VE^#T-7]\$B[>N-C"OF;W+#>H@KQSDPQ]+?]2U?Z%/>(D4
ME!#>25.U<8^U6T'B%^<U[GQ&8^%F\^9; I<]XO,)Z@L>A04=,@\69$S>*)V!
M,6VM5U;QVQ\_^93^2KO[J51F?#M9J5^[HZVW^T.<F31X]W,2+WA3UBY:QN=3
M4>3=S\[11]E9_RXV=O[8V5C_U.WP/[H;VQ\/.MOO^,;V#QSGCX/V3EN<#_^W
M\9J=U1]L;35V-[YN;G7>?Q ;7__9[:R^P7%O=M?6M_"^;PXWCF)N']+#)O3_
MF1Y\RXQSFTPDC!M*P"=%;&":4*,M"&:R8&YI90Z],1?H$%E52D])*<V4^,L"
MA^Q-Y!RH<HXK:CQ-+BN5='*-3J+'.HG>I%IL547WK(KHB2I"2?%2'8:$; 4!
M80-QWFD2458J4BXME4LK<+$)V_,YU3H["5UHM?3O03_N(\\<(B#FXY ^40K^
M=H!$FYP0\.&!VYLK"Z]E\&YL(JBD2D=4-5H!<E>G=- Q9<.0P7K%;D];._W=
M_EX:N!'.WC@8\VZ\>54MP@P6H?-VFIPFL"$93\ RA>34).)ERB0)$,Y)E15K
M.K/ 8I2[JVB=]PD%%#$-"$-I!7!9"$(T(2CN;;96Q9GY7,7HG#!ZRMJ80D<Q
M"$[0[4<'4E-.##)NDF-.0H8LJ"R]L,W%DI3/IT;T_,L>/"I"F\R>21;&J]9N
M&LU"W8[3)E#2Z?JY>AF?O&NP>1Z^PEVJZ%P97G^*MF>F_NX:60?DPC$H,D7I
M##4Y2<LLU9EJ=WNF>%I-YSBPT-W=QYE<&YNFDP:RQ_ET/].PW=WM#[JCPP]E
M?S(-1V]VX]FKC-.@VVFTU<=W_DJ3KIO5KLUBU[I3W)/:I),TD9CL:"FT+(G%
M94 H#<'X5,J<ALM;U<P<&KT9Q!8E1O'2=,8L>R(^*BF"L)E%L-+; *:4YD+Z
M*B4X-C-?K9IB837%*0,61J)'PB11$!I-$8EE$;U4HUQ"\R$]+W6[^$4O]7:!
MRZ>E+IY92'.29C/N93"5J3SG^.:])E6\^+C"?5,[5,23N,+O:3?E[G/I&?A
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MYY-)3KAUF8 RF=@0+5%1!^JL88H[%.&FBO UQ7CP+(A$M0P4H,RYB58Q9H+
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M=4YGT^/6L?*>(/>$&TVY2&7VBP315'2/Y6=S/:%^]:G*/E6X/RA2D#(<'PP
M?FG$&WP,:\R2N:K_W" CM5S+#AT%DA6%&EH0.(&AJU[HJJ$7.F% _C[#4=]*
M1)V-SC2>*\5%-;EC-K=9\NEV,_F,Z;\^3O_Z$DP\S;#^^G9\<_GY:GK^_NO-
M5PW><Q*/O_[XKIZ??(P@N32^_OAE_-?)[\;Y21Q>_+A2+X__-G3?M733Q,83
M538L"K\1VY,-&@8^+L@$COOBC3*T;^6/$NA*C*Q%<=J$WW[HN(KFF[H;$,-5
M"'%"U31<UX3$-;!,B_%;435=%?S>*;^UB]__!K([FJ&;,K%U0S84+9"]P+%E
MQS8,VPV);GO.BS?J\':]H.;W0,(8GH>8\70H\=2(V4^>^%2)P0]N.6?!'J87
M:*6#&6<6$J"[;6+S*F9<FH$A>RRS7*.,4C8,>!VMXTB:8+Q\APU$,1M*BZYP
M(;M8E%LP3;JKZ*9E^\30--LEJN$X-%!URT.#Q2IG:ETYJPS6HE1^\F%294PO
MP[E\-DIA9\FG N:%OU^&[\#[@*<A\8<J&IW5T#[#D'Z.4__[@8GPY><_#%Q\
MU DUV(GI+K5 A$--]GQ/D:E/5.H9OJEHQ@N)@IY/@/1 6[K+>/390QR0[7FN
MSUQQT CPEO/\MRF..8</X#=VA"A3IY])#,)$I4\C2FLU(JB3,62;N70$=X^Y
M>N<O7ZT?' )-6"UOGD&Q(TR!-C&9Y/15_<OK&JXA2M@,V4VO%Q^WHBS$F,"_
MGF<70X5G&%4/8O7FZNLA^VJIHLF_T^TAI 5W?JT,U2V_,_6[7WK?G?<-5G6&
MNF%T9+#.T'+-CHRU8X2UE?7&\T!7[K;P CLU>,Z:*ZBKED[OF=.=& [N.M.O
M:C1[(8#]0,-QE9L*6B M&LGY D&Z*/FK)WL[2MT%YQM- !N<+]YNL5@=Y+!"
MX5*@ U$R+_FLTYF_#GT.BLZ8<7![S(-/(8]"'ELKC]M"+VU+GJUPF=SZ&?7:
M@;O[Q')3UWK'OB9.Z$;Q92DOW.4VU9WS:]\'6(M![F^0.]JAV.INQN<]&_S1
M^SR5%>1<-H.MHN]E,8(XG%.WJ/*PGR3^:9(FBU^(79^'WH"[P>J7[AAV0"W=
M<U73,-R ^)X>4I/XAJ,$6F#<L=IY:[_^W'_/U@6:JPIX_F?1D\[:^/M?G[&C
MUE?@_=K%MX_?+[[\.?KKY.?OYS]&\=<OI^I?)W^.+C^?&;<Z:[]\C,^QH_;'
MQ^]?/W_5+M[_KO[UY=UW[,B]?/_GZ.OG/^%9I^;YMU%XWCP%QU<LVS "3W;4
MP)$-335DXFNAK(54=P+'"JT03\'1;B^+=K[U_SE<YC[#XS55^MCW,VR";-2=
M*@? .=SP JM*4YN'R,(A'*9#L(+ T0TS",S ,SP:.KKK4=.R<7%9<WUG1P[A
MMTI(I\(I;.84YL=!A[IO:5K@RL A33;"P #WH-JR;RF!X]' 43WMQ1O3:)%/
M>&X\ZGWHVK.?BOH(0HITZ)$DUS8C^4I/V&UW8;FZ'H1@@ES#L,S0,0W-TWS=
M-A13=<Q=N0N1/VSJ*B[>-O('+U \5Z.0.N@Z_# 55?:H;LJ:JCF*HOF!KX>0
M/ZANBY"]]F\=1?[P#"7V@[>@A*IV8/FZY>B.$5B*HRJ&15W5=3W<.J*)@'N_
M5G0><!N&KQFNZ\N^IH(5I2I%*QK(H>JI-G$THM#@Q1O=NMVLW'E\Q%9'W&>W
M#Y 2ZP\="[C7)?E][F+=TE.GW845^ KQ ],T M4 S^%0ZCJ:8UH&44QB!"+@
MWI>K^-0(N //##6'^+)E*WB@JD-E8AM$-AU%#53=LQ3%??%&>W2\+>KU(MX6
M!G0C QJXH1XJ@681TS9HH!#35RA57%6W/:H15<3;^S6B\WC;\QTS" )##G4=
MC*A&B P)D24[AJ81VW9=@YAX*O6C\<B?K\+=OE-J^W?E,RTR%.GD'E>DFHT3
M>_?OCCZSC?3!0TV6*\'C]]I>^93/6+/7K]H0J(-%"-(2MQ<BO^[N!.SUVO<N
M2=.;D,(W0\>!%$SW==<(3-=139VXFN&%Q/=\(IJH]A9.-)NH'$UQ-)L$,O$4
M'7(RD\J>KF@RM4GHA[IKA[H'.9F]J^--=J$C'5P\$99:6.I#M]0B^=O26L^3
M/Y=JO@/LD177H+)AZ:'L$563#36P2!@B,I/[XHVYLR7K?5IKD33N_4K!@KU?
M*5BP]RL%"_9^Y6I(\KO!1P4>DH#M$7A( @_IT<F6P$,2>$@"#^F^R2Y!% OX
M&0$_TUKX&2&/0A[;)(\"#FFW<$B20$(2@^S8( ]A+X) 0GI:^NY])\(F9.[;
MDG*O@2]L)PA5U2/4\EU#54-743U+]RR+AH9G!_8=YX <<!//^'?CKY/?]:^?
M_XHOWI].\5S0BY-WH_.3C]_@&=\OWI_]N/AVA6/XL;PL_-?)Z/O%23"Z&/^A
M?/U\IER<P#B_G-Y<O#^_^:K]SM]Y@O.]6$1"T@/-=&C ^G<4V0 >R:YN&;(9
MZ*JB>4KH6L&+-YK3HI;@_=OZ3@3&C]Y8T;3_ @-)N(+M78&BAZ9A^IYI>X'A
M.IYG4LL,B&($EJ%ZCKXC5]"S+J'G<P?S+B'+#53=-T)9LXDE&]0T9$?179D$
MJA(2XBN6J8$[T-L$C"= D 0(4B<R(0'AL::_H$K@:Z:F&Y@Z>)[O:M0P/%.W
M0]WU_6!7_D*D#IOZB@40))^XNNV:H6RZI@WY@Z[)7NB9LF]ZEDF]T U<@J<2
M[ZK_O^-]_")W$/A'SV$\7=6W-<4*'24P#--5(,Q6W5"S54\/;>)2$6SOUX V
M\(]\);0M7Y650#-E2(Q"V?,=6]8=7PO-P--42E^\T=5'%U^>#_^H??V?_;OR
M$)9]! 15]],=@:"RIL<V#**JU/8-S?8,V[1<WS(4P]*)KCBN'SHBW=F7MXX:
MZ8X1!K9M69KLJICN:+8E>UJ@RY[CVZ$6*'YHZ"_>6%:+*F/[-XXBVQ'H4T^+
M/D5=Q=<-V_8LW=#-T+4]70M=XA$5OE TD>WLUW[.LQW%=#U')Z%, N)"MJ/;
MLF<%1 Y=EX:6!8PS$#.[0^!3 OE((!^MEWD+/ V!I[%>TY1%3*)8FF*YF@'A
M/W@U+31]HH./\P)7-$WMS94UFZ9LU[,UW='DP+$@%5 \!9P:-<"5@8-30L]T
M _/%&]WH Y9&BZRLL-3"4A^:I1:)QY;6>IYXF)YA4L7S9<NQ'=GPM%!V51^L
M=>CY5J :GH^)AVGOZI@)@7QTT%<*%NS]2L&"O5\I6+#W*U<@'U4.[J(<0X#A
MWP]VU/0\W\J\B,+I0@U*TX;F/JI0&EN]++-&#6J^-BP5(U)(-S2C4I3,:O%3
M:9+F$=N)CB6J-)0^T4E1H4\H#'U"';"'$+C+!P?+_IO1("KD+,J_RQF-68$+
MKP$?C87^299>1SE[)G]I6L:!Y%&I #]]!2,(I"B4CJ*7/(JXH7Q810I1)0S]
M*I6(Y(\(/ R'RF:0QA)) KBGOBF%::89/)]*>9E=1]=868.7PY3^^S\<3;5?
MY]4P;]*L& &9<JS'%4"9%%?.\X%T,XK\D13E$@R:9B2.IW!!"%?R:AWACXS8
M,@:I'H:K[O@QFQ?<ZM$XO8%17M.\P(J>=)5!OHLC(]*8X-O8<V\H^8YKRLL#
M(B%<PB9Q:[Y#Z2S$;W(JT6NL%<Z(E/I^F0WX71!DP1,F),-5E8K0,'+*OF51
MT4#RRD)*TH)]E'H@M0QY8("/\N,TI]63:CEA/) HR>*I#,\>1PF[OL%5&!J(
M=0G$\Z/,+\=Y@= &^<HA^6Q(&?UWB3T+T7@,%&"-"[0H8LI(EM;SG(\A1 *.
M\4F5")$)O/Z?"$G*W@+_)K,E^A#2 XDC 50/FS^*C17#1S[G]"[M($!;)%)>
M>M^H7R!Q2#*5BNF$XC/')$=.)3!J9#_),F07#G_ !+,>;%#26F204YD49ND8
MI6=.E6E%X46JC\D4-20-0Z",1*X(5HFEE O?O0]G*@")T^([T@3$#K0,#! 3
M'YP$2#<IXX+IS9RQ Y3V2O 'BT(V7!\ KM4V\3.2FN0C*41MA4R$(LF!(G>*
M ^@ATG4UH(?TJ8#_L (^/N0M/OD=/)E+493X<1F@C4M@_ 5_,5,>_- #UDQH
M944PF;IF"Z(#B?[C@^5EDL\XNJ ?()G *1+/1 $^\V]O?)@9M3O'4>;\ ^ V
MZ.SB&):XC1Z1&_62R<D"_ROR&AI?@:F=R"OF#8"4<Y2^_UI<P*DD1IG?0CP@
M;%G<?<N]LE:!D[1&U#1KB8J-GS@G5J!0/,04ME13H;JA:(I#3#LDU-=T^#<@
MYM^V\J*^:93-U[ZNJ.QEX$IDYC=>D?B&3/,7/RU2"TBUQ)VM"/N@$J^"B-S*
M3CPYIVX!GS!.J<90^M^%J&^QC 4LTEU%-RW;)X:FV2Y1#<>A@:I;GJYZX=\G
M#, ;_B?/D;P7*UAOT_$X8G%!?IP$;^L(R0=E.XER=+YE1C_#&W^.4__[?JM7
M^OG;JGKU[:_Q^8\_Q^??L.+TR^@"WG/Q+8[@>O/\V\?1^?N+,8Q!N?@6C'_3
M/\;T7Q^G?WT))IYF6!?CKS\NOGR=GG\[U\['I_K%R;%V^>47&,OWZ<7[TYNO
MVE?SXMOO&KP_O/Q\K%P>_^T'GFTKEB[;@4UE@^B:[%J^(RN*3X!QAFNX]$45
M798T."X06]VW'%?Q],#P=<.G*C&MD&B.0SS?,'P#@G^:^V0"G"BRDC)<ICGE
MF;_VYYRY%?HO2/22$>0L>OC]B^,-J1)8NDM,P[8,XH6.YE@@-Z&GFL0W;'^7
M:OD$:L2>^"HJ8 3^&B9P@=H]B2#.>#R09@$XS@RQ5LHL9Y&A5^8LEL?0J?*[
MUVE\S=WL-8%TH\REF%Z!\X8@P*<4*YEP]55Z3;.$.7B>/E1Q.9=/'OA!N MV
MO@Z!,PQ0QI.8_H./AN -C >[F 7\:5G M[1Q<1"%8>1CP ?QW 13#[\80GY'
M6=ASG(!(Q])'.H%T!,)%Z5V:C255D7^=Q2!32 (@I\(8XA8DX4#Z '&F=#:0
MSB 4DM3CH?01TD'I'<03:9:S'$R;%8C;(9B8&M?LJ@-NPH)!'IAA;QIG B/K
MG1P"O_&T\[IW%E\H]I7X6>1Q1MZ2K?L$"/M1(I *DO T@-<$,(V-* N >::.
MDK1P+8N'(TS,T@*"4?J:197PBZ2Z ^E>^\H2S2K9F8?050 *(\_GP30\<P>B
MV1B;ML'8JD!_[5'^7H("4,B25PST]]E )UAP"*JAGI,,@O-JG.IK-IK96/5V
MC?67,J&S$E!?$D'0G0R$.X.$'5M62<Q+#1"(Y?,"%B-^16L8..I_K2=P#4NJ
MI(A5?T#I/(9ZSO6K454;$:P-T02S,,S0 L9-?"+/X.HZ15T]XR, @GCX&<DA
MV?. 6VATL.81#*4O6 <B,80A=(#L(]*_9TSU2!Z!? 2@PG$ZF7%^;<O U=XG
MD!UBP0#&C&-@9:R 5K]7&?'B\.<39L^9S9I4#<'@=:[1 <;3ODC0Y4J+6_G\
MF;\G^:198I@Y'58J8E=1K-% $A^3: RLR]'@PM\\?0>RY2AV"7B@6 K!I:(]
M)#&^>!8C_ 3<*9/HWR6M!@0,23/,X['D10D\I^)2S>O:;01S<P[,2ZZ$,=^%
M,8=K.F'+!_@@+F<WM<=G5JIIP'BE-)U,TH2].Z?T.YH&<D/ >()<$:Q)R5-:
MR&"&8*9A1(.&<0C(F%QA.39C=_'/ZZ(YUEGKXOA2?18>6S+^+XGN!";"JE55
M8;3DM39X'L1H4UZM1EI=S4O #2W-Y]7^9!9#-_6WNB5'<@)10.-0&\'T<P<0
M,++F8%XS>"2**RC9,0P!;'4. ?8 MSE0H6Y"W;96-Y;#@4A>@43A^/(2D[<(
M1A*C<\W2\FH$&5WNITS@*_N/KVYX?93 :(RC)&Q9A/N-*(%1CN=Y#5>,*,]+
M'N?0A,4P)?^CBCA0MMF*%#QR L%)A)=@E#+@JPIH(3*^"%37I.LEE+EJ?QE%
M<1TKX3>S!^'J"BXPP)4PO2HWY>$&7YG@JSQLY0*G,$MN9VM%E9(-F'D)@"8Y
MG=U<56J ?PF+8<9I1F_=6:\>X?LKX^+/E\_FJW>SI_-E V0_BL6"_' KP-T]
M+^[#MX.&6-7%;AS-;"%BN>#>V9CH;;4L#*$U"N%"&(H1,V312-YUDU5>N\C]
MDBD"6V%]]2A*M:8R=NQY&! SF<&7G&3EE70\F<#=7&:/CB].CE]*'PC+.GZ;
MU2-V)RBJWJI:X65!?\3D2<HI%DYTBT&M6,S"ED29$>Y6CR&D1O@ =ER-;;2L
MX"6A.#VE-+6L\GP\A@   DI_*%T/I4]@6M(?[,^!A(OJ<5\,[F72:-/1G$:;
M3A[EC-DW40'!+MC?QG550 (N*DKJ6("UW/+&C3^&GX;2"=R?H2]^"]9ZOAH]
M^Q@\',[A%_2(4^D(OVO\O7CW2XFMS5;Q52Q]*X.KJIH*L<EURH)\SC*6%U>A
M_5_3 $*1#R,",8M/2Z9MN73TQR<PC(RU1^R*EWR.X'HG5;\&SZ4EG3W-PH>S
M*57B?Y$.)7M@:/; TAT^\JI1"/_F%[T<\(>LOML9&*8Y,'5KX6[\N[J;AYU\
M%!K[0[-7/TAQ]8'FZ(T'6:_Q[^I!O#)X#]4XC9I4XW2\@R0JNU0U5]/$@<&H
MBKHP&/Q[U:P&D+/PF:FK'J8J,#5M8!KJ(HV,V=.&$C9C+$V-22$->(+( C\6
M:V%+!@98+-],IM5=K!7H&G[QIG.Y?9>FO,3&76H 42#*8N55WZ%3K<DV:P]C
MQG$,NLW7 ;"_A_XSB:J;JF3NSGT/$S:?I:T/FN^[,'8MM&QB*+[KV*!PJF7:
MJA]XEF97:\:NYLCU+\T]$&<7[UY(/%B'AX&QR:G_"A+B&R!03I/EY>7WP/IY
MWC/E%,[?8>/]61)F^''PQX2M;((!F&V34 YLH?GB!_[^AW'^^?<?EY^OS/.K
MOUV5AA[5J&P'OB4;FN[+GF4&LFK9ON>[%M$-X\4;2+LHO;7U ?,I3EN)RT"^
M;$T&3=N 0EG].=?PG&L5"G5&KTH(,U*L8OSCQV6.W3A35%Z>-'+%YJM5;%F&
M-3G&6!)>H4D@1FG=^9/S6NZW,O'K!KY1Y$6L\X@;$-8_-B;?X9.!A#5*^$\*
MJI>Q%L=4@M@FYGD>_,*W+G.5 R6HVZ!R=@'/.ODE5:Z]=-&B[K&6R\@'9<XH
M.$B2LZ[1H/19FQM_/[;Y03Y7:R+CQFWBSQ?C1-O2(]J6[+O;ECK8@;2R:^/!
M+HREK@U%UW1+]2W<P&8HNNIZGNJ14/4]VR6!$;2\:^.A"/+2+U*,"['0Q^/'
M>Z,Y;EJVBN@:@;ATQ/]8)WI;&:(M1&@KP[!FO-(,?!H7SZ.;!R.M:NQKAUK+
M$=+**&CW01!$.//1/F6$$Y#0UE7;44W7-\S ](@=VD% '<=R'$TQ>(0#!-;D
M^A<1X3Q[A'/S-[7LT"*:)9O$\&4#&"5[U/%E/:">8JDN]5QS]Q'.7+'V'N%4
MBON<(<Z2]FT1XPA=[)TN7AS_;=JFKFB>)MNA3V1#H:Y,#!5!GKS0=R$_]+'?
M>UU=[$L1:U[#X 8@C$#EV4X'GR_T@(^CV-:0SM-\'HE@D,&^RV<%JG<T8&NS
M;W%#4E1P>[7\85652N>QCV97-3$<QNS#64&M<N_@@G?:P-*R&OPGFN31A&1/
M785_JIK[4W=C;DC.(Q\<%HS6IR!K!UV /QXGJ,#+I=S??GM;U^.E(_0_N+H^
MD);N+;/4@TFFU>W2;P7$ _RNEU)W"+AN%J8IS2QLW5K\"6C+#:Z7,GLW^VNY
M#L_6^N]-<SY 4@!1@?0O8%@Q\O$A?_P*$CMF 0Y:QT_8J"A]+)-5_'R<<6R-
M^)Y>_/SQ]+<#TM>S\;A,Z#\@)]DDS:KMH)5JLA6T<5Y"F/ISE-))E,-EPP%3
MQ.X0Y"']NTBOJ^6Q6O_F]8L[IR\=51^]'/ Z0-VB5?7@_ LR#!A<(O]&8)@^
M?,EK'^QWN.=;&K'&D[ST0,%0PZH@YY[J"SX_C)!FO$\IFF!25:_C$1;(X[N7
MTZ5ZD8\U\D"J01*N^[.D"8*<-+ZNLQ&$2R@+W!%0W& G+VMNJO9RX[-H@H./
M&E39.,-"BCTBR\*4LLJC:F "ME&_@)EE; ]M"31B[; 0)F;PFV8PWKJ\^,'Z
M;ADG9IG:[04ZU=(')LAF/^S:1PJYP^C)VRP.I*GB<-Q#-=,3;A-FN^+9$12\
MRXZUFEYUB@;WSOBBGM5\+UB^5!+Z%:Q-D(X'$N3HB4_KLCFVL,5@(;F9/ ,2
M3WDK(=L0P;?S!ZS;^3VSPE-6+TK#2#[&+D<PI"<04>7^"!\BO1][_V(/ NIB
M&2F]%78-N$]AK^"I,Z\8Y+P27=GS*>NFJPMJ:([KSFR216BKYQ@2,WP/F#W%
MEE%_!C^P6&6KZ^ ?/A[_]L?IQ><G,BN&_2B[8CC[SQSO%36^IXCD(&HA"[)G
M6#"GD/M,*(RHTK]+; 6FTF?JCQ*<C?1S6G7A\S+(S(_-D@F7=W-+61G/T&IF
MX#U\H8(FV A/<B8$W6?E/CF)!H)%C3-&+',0@PIMH*GF0-6,&H3I&F;RR%"Z
M-9[BXO2/#Y?O3R]$)^<3!1U'8..O,H+=^2]_NJ E+B>(OED1XNVN8M=,_#^$
M\-",1QC][9R=U?DG99;C+C:,CUANWLRO>8!W1VT-\^5QQ#8JL#UGY"8OL>TV
MHU<D8YM*%G/+?"BY \O0!ZYK\]X$96#:]D!W'YEKMGF!H9K]9[Z=!A=\^,H.
M#V../GP^_OFE]':$^UN3*]H=2=M4U28IC$["Z79QMAMTI#=+V2L7X>J*-&Z@
M'+.=\2DK3D5U=PW\76,&9G1$"2LF58OD2,!9I,7+73<9EM$2MKB-*8PT2N-@
M%OD"J>NH=U4W]M UM8&J.XB#5R9\E15WQ'7(YFVJD-R\]U42WU$O*Q&E1YTM
MJOPKS;'OJ4J:4>*:+NX(!A?7"[V#ZJN7=5H-DEGPW7M%R@[OB0JLD$98!6&U
M48KV_CJ"\1^=??CXLK&]3:I:N9HRAR__C"BA0-?O=6YW],>G#Y\O7Z[>+:#9
M^L!6[(4F'/Q[OFFAXB';Q#@3])57WQ+RI<QE L$;5@^0?+C\C45MEJ5R8@ 1
MS@D0UND7+@@(S7%YA8URJMTT7DQ#*E(R#B&^:X+9.I>1.=E6B@A(PYV,&$KS
MEVKZK9=6!I+M2O='-"AC.M]L/).O0=4)Q:PC6EF@.CM92CJ*PMJ"TN#E$M\T
MT32]DZ9II_]-T[MO@FZ-%_PYJT%2L*T-&ZZD8[_7R=Y%>HU+>?7N.NGX/6_3
MJ%/ [DQ\[;8*:]VVBD]IB27\Y-9>QZ\IN.D1C3$20'B(DFUJ#RG"[M+Y\F]S
MD10AG-EB*JY8LC?<IOS,=1S5W[U$\ "VENEE$0W9?9A+CAGX+_N3O027?\OQ
M&#WTO'D\N;MWE$4$RV?T4(.$KNJIKFH;FJ6YJA(0JA'?U56;*BX[HT=5%<UZ
M1,?H;VF>-SM&.<S"6Q:@''B7Z.7)&3SC_,?%CS/UXN14.?_];\TVU#"PJ$RI
MKLF&ZZNR0X@M4U^Q0@4-KX)[TF[2VSVB-8I4F)$2(P6VP!^4U0(.2F1"KT!7
M\:]QE&>T IB: \%[E*&+@]C\0A(>._-%<VVP%" B)E ^BW7F]\V#[NI&]MY:
MMJO;(229Q-/%&SFP2Q6J:]CS'=4RS[!&JH@+.RT@CT,8$>Q12/,9W@ZN;F4,
MX)NR,PP8F$05!M?X:OC&F;FO8;Y9\ADE-?Y'3TKQS,A])O\<5O52^F\RGKR6
M/I5>'@41 JSEZ-L8 G..)0'> 5,M7>.J]35-RKXDO0CJRJ"0#);AXB:*@OR#
MW3+H-2HPE<:>G[./G_""6;=/#4[X%I<$D^GMM*9> J]EB_G.30#C=Q^T;H"F
MKK]HG5+?#TUN/CDT.2H*IH=)<<I.%VD-"GE]AMZW>/3UQ]7T$L^^TT[-RQ-P
MG#^"Z/SDE^BO;Z?P[M'X0OOX[>+]Q]&R([[\\NX;.%CCJX;GZ7TW+DZ^ZA?:
MV<WY^)?Q^>=3]?+]5_VO]^?*7^_?A1<G5]._%00A)Z8KZP3/P2.6(A-%LV7%
MUJD;.HX*2= M3&_+"UTKU"R(F Q+=;S0\#3?)H:O4I [;QF#?$YP#FNU!>SX
M@Z_LL 5K;DAU%ULQ.6 ?>G&,AHG_[S*JT;1"Z3--:.I%:579.ZK_?HE8@A-V
ML@="C&'\CEM'(]9 (3.D0 DN*["G J9X-66OP=[""KZ*5>\@;KK!4")G!36X
M'JZ,?$1JC;$:-J+D>BK[(\*PQF*$92LB+PW0^1S]Z^VQE[^LTRLV;(8#&S,X
M,SPSAY5M<D@(>&L5_:<Z!(B=?B/]YR9';GJVYKC4""A$D<0PB1-HINU!ON[I
M)-#TV4XPM]X)YBZ?O=D(ZS&DEX.TD*LKEFW'!S)EX%Z?TV,^JY\K?%.:O\=#
M2=IR(.?S&Y/9WJ]S\^*'/[TX_ELGBN,I@2X#-Q39,""@]ZCFRJX!7/!HJ.J&
M]>*-J]QUQ":H6LR8/PFS%,_6XK1GA_;<4) E+,V6# J^<0(7W$7S N'OJNO!
ME:<%[QW&XZCP!"IX)#_E: :_"6'1)D+GZ*%C4-]481I&&%+7MW$_6PCFR+8M
M5:]SR"59<S:2M5JT(#+Q*F2_64I9X*$\45 ![AW/SV3*/^)OE^%E!1O(SH[]
M%UB;F62ZARV9/RYQ5Z*E*3Z(HJ6;H6Q02F4O@!^.92C$-DW+T!T(18;6'9+I
M59*)+67L:*%)6D%$^R,$DZ^;!^N^LR9.)<:;S6W!UWW:V/B9T8"=QL7ZV,&M
M^!5B=K3HO^JP>R5^)',#M3OCR:^W>*K3+1S*E3BF'@7:)8VMS2'&[J,:/AQ?
MRI9RV&9K\(^LP-08/R^0+8T\0H]5.^;!#$&3[T\(:SA#G-^8$CSEIG'2&YBL
MG-:>O(9&KZ%060DMSR$H6FZ-$VL46ZU1N#LYC\HZK/.HV-+H7$38N=2X1DPF
M.7U5__*Z/EHT2AC=V4VO%]^PHO6-O9!_75'"M8>.8B,QJF-AJQ=7=!HR.BV=
ML<V_<X:*ZMSYK3)4[_SNWJ>Z0]O1UGKL X?9+AW<W21V3,/;I$DGSY]Q,S'$
M0VRX6VOT8=U]J&QGYG5^?''\_O3\].)S5=/Y))V<?7K[QZ=/9Y<7N#L9_CW^
M[>NGLT_2Y3OIW=G%\<7;L^/?I+>7%R=GG^MK/IY^^N.WS^R2RP^G'X_QBT\+
M9%IQHNZ]6E=]4IWUWGIW'H+*IS?HX<Y)0GB0.2N2G<S+:ZRY#>+H:1XQ;_YN
MYI#Q),FYT_\X=_B7<X=_='["JIC'+[E_+3B<. ;I.0)[5K$"P=U\4<*/$9WE
MD8M5^OK$B:%4/[,ZKX2?0DD0NSXO)Y/JB$F6!X":C^J3>O$MU6&TLWT?;*EK
M)T='L4V)*[#5\_O U?.50/#L68MGU4AX1L?JD&H.*PUSFU$&VSJK%1%:SQI3
M%$2I89-^?WS\H4[D^=-XQHX)UNQLCYRRI;A7TJ@$F<.!9V3"=NOD++;**#R3
M\H,55H]N$?B:G?&R$-ZQ8UYZLDH!7,:C).0X3;^S,L@L8-U@?IVR(A&N1C&-
MF4.>!ZE?\BC]AN_BFJ\G?Z)^F46S)>73NC@T7]&0CCZ=OGTY.YP[O).B\^._
ML.V>259]=#+]!P%.:L#Z&OR?KQM02.L*_G8P''@J,I=2+RWQ  XNR57M 828
M)?5L0USSR)OJ+SQ?+,QGBC^^;459T#\I9N=+S\\$N:%L9S"C6%[C[WMT1.)P
MP&"CQN0[O6_ZN,2'QRK@:B">982G@50-HXVK\!4LH<(]\54&PT<\7S_)*V!E
M=AQ<FE40O,S@SP\-3I 0\8HC F?G.(PI+?@I@#?48U2&%&J$U@0+B_7Q%;,>
M _;A4/J$ARVPI7:TWT@X37G-&3A@?ZFOZT^Q#NE'V.6W_ WP#BFT_#$[^F#Y
MPP+4B]YZ=B4+RQ]S=W7KXI@DRY]5A\TM?XQ'S"Q_5@ODK6M'J\8+LG"+$"R5
MK#^LD<K8A'DQ?_;5O)R&QS-5W ?FY0VJHXN,$,J+X>BA2,WL=M-;5UGPE-][
MMV RMY#3IA#69VA<@6?$96^.A'1;R>K2P71V]%1=9LFB_#N(4YE4'\PL2$/!
M'CHC<OF(P3D.T@:/YZ=I\/,5^>&9O!J'BK;:_\'H5QXFB5_PTR;/)/2C45*?
MG'?O&93UZ5L["5?F0WC@;4\4TP!+^&YB;L'1\MYM\"H;N<+*-@UQDV,SQ[!P
M6,PU 5FOSFM9?&#=V SJR8]J69+A,02I;- ^*=FSIFE929V_>*(++P5R<4!C
MCA+)#P-AQZ\ '=D.Y9OJ[*A*[[ ?)!I/8CQU*LUFWJHZ8/U>Z@#;:&U9L=.$
M!.QP.]9:!9H @@"SO8>X\ZT]-0I%3F+T*8V"9O-@]WK122K8_I=JKGAY-/;0
M1?!Z/AKRA/FFTP^?!E(<_;N, HQ F3,@$XRL&%9'F?EX50$S"-!O@(5-*#HI
M#.W91^":_.\8;,"E(^[O6,W"2[.&5^/PHDQN(1X*Z)@%JJ?\&'J2L^YA5IYC
M>0:O'%9[.?)Y;(([GN9US#*><?2JVCXU:T6'8(6=D1NDS,+Q8W:2*;><]>$X
MJ1?71[ "%\H)0SZ=E/"ISY;7IO=Q9KZ#.F ]?%XYQSF=15]X$AC;K,^3(,X.
MO :7^AK2/ZBM+B].LR;[Y(K'_4W-J2.3FRC?:,?((V+71W9#N!WKAKB\IAGN
MKNC)\@!/([&>?L<"-#^XK.I:*Q-LRJC1>6:+>//EZ&G5&%I$3 ?PW# .O</,
M)HX1#Z2,XI@OT$(:N_3:"39'@3I C.KCD72.4B^\XW&>5UEZ4W?Z-<ZX@X H
M#F9>!:)J7OX'\N)2 #J(57-C]G#$; O!30U2M;I9&:%J"B1#3-'Y:[C_S1<7
MYB?1A&T@QCO'&+9@A,VC<U:2)C?@2V;DZLO2$E8V)L!=C.WC&9IL==AV,<*F
MR%D".4[S8N$,9\+C(!0OFO%5(G1<U=WHM3G^V4#ZD*5Q).""MF#00'J>$ZWZ
M2;O_>W_ZY[$@W3:D>RY(B'Y2[QB2;<AQ!?&V(5['T>7V"@*%H<VO7S]\O/SM
M[%-7";A/^K$: SL2 '=3(U1)XP!I7F.OHZ3F7MGS/X\_G765WGL5V"./7A,_
M^E&.B2>3FQOO)?B>"6ZRZ2HY]XH<=@1)6C2)4X;K-)#^Q"JK%_TC:+D-+3'#
M+,HQBB;0\M?CBU_.+CX+-=]*S0O$&BLK-4\21#H^?1:$MWZ*)IVDN.0'KBHD
M2,H_3R_./G_M*BWW*YI@,M,\K43SW_^^ GK^_-O9Q=NOGR\%0;=RZ3%VUI?C
ME!O.XW-(P\\^=S(1=PQ'VS,U20##JIW0<31.KZ.K+I)R_W*)BW1<R],48?,_
MD"PG7G0MJ+D5-0L:\V-IH@"I^5R0K7UTZ .IZX<F[9-Z/YWCGIBLDQ6C%CB8
MYOE26#_Z[8_SXU\_'HOZT3:B",3[VE7B,5G<;UZ3IT4*F6+DO>Q)7_+;RS_/
M3F35G?7$]&3E^%A*TFN*&P,SMEL=47"R-"'745;FTM&GXX^?Y+?IG[)6'=5S
MC1CUQ$=P$.S^PS.#L;$IGR9!ADU\S;OA'I^PDW\6/@ZB'+MMV7Y^>&9-V9<,
M3C*@?DS8YC_I*DX]7,VN"%X?:?R%K?WS \FDR^R*)-&/ZN#B&6A0U:(WE#ZQ
MY@7699@@^E;5IC![)DR9]_+=T,:I''Z<YH@.,$Z3"*8WZ[*H[IKU-\Q:I7A?
M737@>><B[W1+>4<I.\L).Y+9&<T3["7%]C@ZR?&;<91$8^ ;;Z2L&^OH>!*G
M4\J.-UI8LY\7LV]&Z9@/?89#P8[0170RH#<VU<73H71:/0EW<+*6XW365Q(2
MO]YAB3T8C )8DO"!:0&9@9G!L$%56-O?%8A,EK!^OQ'G VN!)2$MV!E,18I[
MH]B'5V7$GU$!5T;)'#ZT.L?IEFH-I<\IPTBK-T6,$<(&9\1Z/!K[N?G$L6VL
M01QL"&.,J1HB^092ABZ%L$[\L ML4\/FNUD/]IQKO+&S%@A\./;@91%V!K*F
M[ZRL^UE3IA2C-"O8V2E5JR?;0#-=Z$!9!M846U0?-DVZTBL8S<ZZB+D-G6\9
MK^SH+=6=&]*<&=)Y;V3  ;VQ*2UGW=Y<5^8G7V<@ZPD:^<9-5>^7A <0%4S?
M@I1U5=>X<2F#2:XZR]%Z\5WU-*CVM#'3#<)15!M>4M#E*&?[U^=]9:PO%6'Q
M4+O)50+&G[T=.S_KJ[ GGV_28.W-HR@+ZIWR#$,RHW/C>961H&1=N3X:2FQE
ME8#7H^7I\#TDU0O!ZH A96_ FQ .IF"[ "HP.H_&Z0VVXLLSHL?8^,9W"TA^
M.2ZYO4 7FC$'BU2?S0<?6IU'6.\_6?"$.'HT7+R+FGUW#<:$<ZI)">RLY2?Q
MS0@[J$YL!][S?2?<O<S]7HUUT-@ U#SJG$^Q.HRP[KOG2[B(7[+:&S?ZE,$9
M9 SD>D8:ME>C:GFOJ8Y;@ZXCQ-#!)G?F!OO2_\=5%(@&9.(0254L<@WSK.!1
MD&!LW\$\SF$=W-@06;$K2^,%H1A*_TIO,.1K;NR85NQBNXTJ%XX@XP7#4&2-
M_[,6<=3VYA#PS#!$?D ;$I80V^&9CG/XN4FZ>'CE[/D4U9SXT]G&F\9#&8^9
M4F8$-R"E_"3'Q7G,T.S9(U=09<!D?"8V\ZUX&,%RU\ZCUWS"]L#BEH1JFHUP
MB#V=13I-\!Q0*88<6[?8_\2"AK((TAN^NP5?B]VX5S0%VS$91:P?=]Z&/EC4
M+#"MC6 /M!1FPB(<!A!58-MMM2D8=(PL$+C6=NS@;8R:AV0L<*QW ,:ISYI"
MJ^W)O5&5+QC+5AN7ZC [R,JK11R:QCZ-F\H*<8(#FQ9-T<SD1$E(JY-3^5;)
M>5M)[=%8ZW53SJI0LXIL61K L#EI,[6H]AOD11E,)9J DL;U.<UL8^+"/I)J
M#\<UB1$-I3*5E?EEZXQL R*H.H;[-\QO+3\@]4$&F/6M7$^8^F6U#0@]1'4.
M*PNM^>:OV1/ K<V.@XRRA@]F)T<O-*17FZ>J&*"ZC&^@K'9ZP/,88W@XW1?Y
M.\&LN:ASTJN4AR*U6@)19@Z2<RW'# 3S80_TE4ECM4^2QSRS<"8LV1X?!KG$
MCH;DR#\H<<VMY"@<]2W5GB%^DF/0R PKO""6;*$E SN',HFF!YZ3AWPK54)I
MP-&(:@&NMB,-9ON2V.8E,"!E5NW_":A7X.:#:SS<HK*?U2:=^49+C-*2*T3B
MJW;.5H^3,PI/2AK&>4XKAD^$PEC%@D GW '%MB_B*4YTB)OMP*+>!CVM,NY5
MX6R]_7^6D,]V::$-7MZ+*#8IKMZD>*?F/M_F)D=;M;FI-5N9/C5*.PT_=#?F
MP9TCOXM,G;25[V;P*A$')N'H]A@$TI@7>/([*%>5@&I'U=AJ#\:!>;B,W5VG
MMF$45WGM*CVX3PTJ+5C:E\N,S3P$7!@:WYB*D7#* HOQ!,^R2G*6O"V8IQ48
M>4VP$I83<EO4 ?R5?BP$U,"30+\93S:86840)2,<5'4>7YMG>SS']MOY)-L,
M(%_C*VX[:<-=9]*RZK1HS@SRPMKCPN&2W!A<(AZ/ +T=X#/'R/]/5U'J[:A/
MA:VK#BW)F^'Y/B-:ZD;&Z)$!F+E1 /9 &"/63.Y:,U$/><UD7]%['8S.<78;
M@!$]B<47X0XQ'D_8F@([W[(*FU?#]QR!V:HW]".>"0,2@:]1=]BR*4,2HYG,
M(.]QX9>\?+4^U9X=EA7$?ZAP%=@4EU6WAK9E[AR8U1T:FK754^__SM3O?N<A
MC-4>*H[=D;%VB:Y=&BO(@&OT%//XEJ57>!Z >,=WHAV[Z\RHBHN>?D[.0QY:
MX<XKHXA\DA2CJES!0H[YT>2Z,M@ WEG!Z;YXMDN[2/$+Q.#9.\%WJY(\"FBG
M5LXG5<4_%8"8Q&""I7I\&PO0T\QY/1G"5']7$UY#@GI%..5IM*L3TW_+EMMW
M2X!>"8?0*J%5N]"J!]RK1_SO5PRT3Z[&Z/N4AN%];&]7*/RAB>2ZCM+<->.=
M:=-#)'W,,\0@Q2"[/\C-8GX)_VOSZG9KS1 >K[QL?59,1Y&ZD,C\YSHS:<X@
MPYM;-05C8)K.ZH3L'BG;8%);A!="'O8I#Y;:-GF87:JM-'TK9:-]E#U27SX-
M1?<QF?]Z1/8@U'M_4U"U@:.;+=-O(1![% A]H&MM$XB>&'RCMP9_1]623F0L
M'R^_W.GLM,VFW!'!50>VI=UK$C9B\&YLQ?:I>5^99#B68%++F>3NA4/[=Q!"
M/-:AF3E0757H<+N99 Q,1S"IY4Q2]0,UM%LL$:ANF\/MSVDQ/_?K@=7*ABRO
MNS3?$7FV("M7[A?I#9H1]I.R]X\GJF)TG"<=)/O]).^\ 1=JMNS*G8&B/9#9
MME[/>L<4>^ J76=*%^G>;^/7^ZZ[2X;MD^%^YG*]0+9'29DN"I2M9]&>*I2"
M16NS2-M/\6G_SD&(QWKK0*IB"QUN-Y,<YX'"@6#1OEGT0!-,?\UL3RO(=\7<
M.TG0.].)MOXTVRVRUL#N5OE!B%DWQ<S0'EA);)>8]:/*)4K\PG)TW'*H[D#5
M.V4ZA)QU4LZ<@>UVO3.@@R[J_G[HSKNH_B_$<!#'Y(H?Y)#?G1@^:OMV#PSE
MX^??;L$W!KIV_P[7QY-@SZ4Z(<J'(<KZP+4?B 6Z+LH]KSJ+_2'"T E#MT9[
M/V0]PFD+6>Z#+*L#R]S2[G=%EGONM1] R.FOV^X++OB\&A E?CJ^!;"Z;IVJ
M,U:U0_91&^AVVQ"HA#SL4QX,\_Z%%5'3WA*@1N\M0(U0[ZZHMSG0!2"9D(?9
M%.R!JC_IKJ?#-?>:V5M[W_OURPM:W)^K;)]?=\:*K3?%=HNM.NC#7@ A<UV2
M.6V@[&D3F:@IKN^=[;N<<W_+B<(:': UT@>N*SR@D+GG+3)8AMCHWG8/J+F'
MYP+[LJ)V$L4EGAM_^N&36$QKSQ3T8>N*:4(<]BD.AEA*$TMI8BFME]IM#=VV
M:;<0ASWVE@_-)]U8?;C&7KNS5M=Y:]_[A;0Z4<E')#LX1$9SV^U"H@KR;"QR
M1*&JY2RZ.]CO;YU*2,9Z]E4@WK:=1:XXVJ[E+#I$^\KB[I\*XL44_AM$UV_^
M%W[48QJ3["I*9#[>5\XB [^5>1&%4_Y1E 0T*5YIVM!D(O/,,]-P9F>)5(RH
M%*9QG-[@)IL@ROTRSZ,TD=)0\D<DN8*W1<GB,3\#B213*:,AS6CB4ZE(I3*)
M"BF@,*)  K[?%",IS> #'U_*+\WQNL8C\<V3,H-/<O@ 7I>66?V>7/*FTHB2
MN!CY$/WCQ]=1@,\XRDM_))%<FHRF>>1','M\$SPLRB1\6^3G+P<P$1+#][GD
M Y'AOH$T2O-)5) XEW",$T@JQL2/:#Z4@ HHE 7,>L7,HL3/*!\BFU#U!TP@
M2J[AX6DV73V_^=<C&@<XH9M1"M0#"L)(0132,=Z$HZ'P;YDO3:\>X,OA3/ZZ
M+6TK#HR:43< (61<A'\S2J4Q/&V4(V'@JT]T4M"Q!V33E8&D*9HZ@,=$,'L8
MI!1D$1":"0R\#"YJRB(^U0=;0H A7@:?@"3 .^,2C9#T(4OCB-3DW2E-+"3T
M@T1Y/4ES)GBO,AJ3 B;R&K>,RCJ[>]D( IWP 2_>@%^TC==/,NXU>3F0/M()
M*4:">%L0C^G\Z9^G%V>?OPKZ;2-\2$!0^)!<IQEZXIG=!1-,P>R-":L<,1,#
M%@3L#4P35']"8%(D!JN1AF%."WQ(Y:1F/BF!CV&N,1H(L#(^=TZU$:D=U%!:
MSYPEZ/^$-6N[0 EK]CAK=O[G\:<S0;UM1&^7-ND+9:AY8(]8*)5A8 D7WKI]
M_@*,66&045*R:)>$(=Z-H;A7YG@%//5]BC>"\;DA63"0;AHO(<5]#[^)XECR
M:,.HG5[\_/'TMP%0KXQ)7@B%.T1K)>V3>FBM<DB]ZHS3BV F\!Z2-7T[>%XJ
MW4 >=I61H&2G%/@I3&N*^4E:7HVJ7"7* NG?)6@P>&IX('ISEBX#22#?RN&V
MO!RC9O $%322%&/V#8X#KDQ@5M750 EX$&;7D/:R=^ ;P3(,),CP1E)28M2
MSQRS (!"T@YCIO+;RS_/3F35E6)Z3>.\-_DBIW1:<FL&(X P*/)G!BB+,$</
MFCEW(TYJ\GB!L;,'22."-P'KLG*"\>(8D_]97>&__\/15/5US1QV(:D#R9M1
M!'DZ/B"&&\%P!J &4SZ&B%PE*=8(<"ASCL--$7#QFF135FJA5Y#H,CL>C2?P
M8(GX69KG?,!I5H00S:6L.G%%$Y2#P2VWP(/.Y=()L\HW*,#\P93%RGA],$V
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M44,@:@B<&J%5[2&<T*I]]S3NQ_GNMT;4LTU, J?FT'?\&N[C&@]:OU(J!/E
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M%3[@A[_]V_[/S$S/0\]@%F:7<7+$Z_ZR35+]J#,<;#$_I.GQCKSW:>'-5)B
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M(<>745'THE7YT>9S%4Y1HF%Q5,,[QBM&7<?I(J?E0,HR%&C8'B(.621T&<"
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M^$GE>W]EV=(2>I7N^#+<'8K;8',:]W6*4YZ:\[>B:LW#W%%JNT?Z0%R(+JI
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M(V$!=;J(RO[\._?59_L--HVUK)"899##*/(Q;ZT0+GMN3,65!/AX<??%6,B
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M,79CI$>*AHN4A* 6ZQ!"6'.-9L';5#)YQU+::>@M"NE4R]:)XU*OEL33!IL
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M"HA1*8HU9;#T<Z7V _;<5:@!;\<!KU47=M6 =R?@?5%]EP'$[?2^#?9QIP;
M&@ ?&P#K6I$: ,L V UZW6XG>!$-@V$K:"\#X/8$>.0)(R3H;NT@;#7ZZPQ?
M )5V(U@'CUT"FTZCL^;KG>Z.XB<2KE?=A[QH-7SN.GS6Q28U?%8[Y_5[_4'[
M112TAOU!ZTO@D]O/6U9V:5>W-90&C=:ZB#/[XEKKG8R[&I*N@&6)LK[NR;</
MD%E7J=20687,87?8;P)D=GN#DH]1-_?ZH#(8/E)Q_CQ-1^&TA)V:=:X*?\U&
M)P!T&Z5)9&!M5T/(2SH@5MX-:DC;#TBK:TYJ2+L3TD0+_*@<C>TU85,-8#6
M/2V U94C-8!5 *S7"MK]UHNHU6SW^MTO-V.IEBSHW-.$[32ZO?9J=]Y _'V]
M-1_H[DEY26EA:JC<=:BL2TMJJ*Q"Y:#7Z0:@ZPWZ07?@])=](%1*KPGL,GTO
ML&RM]_>UQ=_7VS=_7[5_4'EI:KC<=;BL*U!JN"S#93_H]=MM,(W;@V&[W_QR
MS9("IAPQ[6^990- N#8RLA] 6)ITC8([CH)UD4F-@A44;+>#9J_[(NKT6\-N
M[\M1T+ 4<.I=J94&0 &BX.:\P]8ZU7!/.FI4%Z!&Q5U'Q;K:I$;%$BH"!'4Z
M_6[_1308PIL?03>T^2&D*[66N LW),\,UP$BYN%L@$O\;6>->HED6NU&L.:W
M'>87;*\M@>[N%&WL>BQ>6O9#!N.ZV<?C-/MH5W:_;O91-_NHFWW<H42UG[:"
MC<6LUJ-V38\*VIUAN_,B&K:ZPR#X\I $NIMZJS6H]3ZV]AH5J;TGD5EGTH>L
MOQP&#M:%;#4(5D"PU6IU^\,74:\YZ R^W);4L<?^/2U)4/_[JX&PNZO9?&NB
MKH,:#/<##.NRM!H,[P)#40C/U66<%_P^[QR'DGO'EYE2,[!V[P! ..\(!>$L
M!0QT8?-U.CD&P!LOLKB(5>Y;_I>_-SXTO'=I=ADFS@>\7W\](:J7J0HC+U+A
M5&4>+"88^QE\&[_X^OT'[T.8Q2/XE//%$P A>.$;M2CRL>:6<7[/XSE_?>*=
MA/.X"*>8FOQ)%?!4>N=KL*^GZ?B3]Z\PH1_1RRYB-0*9]GZ/I],X!&B_N,+G
M_C6<S5_!*QN^&? X/:H,MX;T&M(?>TN#9B/X_VI,KS&]%$-N!YWNL(5$A?UN
MM]..(C4).B'"^E^*=,P__'<K^.%O#@?7,<!ZA.  Y_U<Y06==6IL^?;/15S<
MXJ< ^.'EWH=IF.P2F!W/YS#V^+-W@F"&FO8;-8F3F >;I9]OO0N<#UY<1$ (
M]T&TF&)R]3%!WCR+IU*3TJX!;]<!KU4#7@UX#'A-_F/0Q3\'S1?A[#*!V07-
MUK^1)J7=#C[_J2N&XPS4&D(YP@% BH>CG^^IR42-Z>]<T<9E&KO*)*-UO*!Y
M]$]35?CG(LP*T$]YYCR-MB:8,;#8ZM>4,_N!B^T:%VM<+.-BC_[<M;C81ESL
MN;@()G$*)_NK 2,GW>UZ%<FVP-@S1(9UG<E^H&*G1L4:%4NHV JJVF+GW^CJ
M"EH(BYTRP<S/68A&XP0L2'0&GLW)'6K\H 8SOL"2]IX=Y^9+;C<E[A72:B)^
M[#AX_L,LQ*T*-7*:B;1ULI^; 4B5>JVZ5]3.(VBW1M :0>] T.YZ!$4(S.(Q
M=3TA#/TM >RH$;1&T.\&07LU@M8(6K;,!R1VG1<RH:#9FZL,LX5".*SA39A%
MC*(.*A( ?K"?\H[Q8QC@N,S"V080E+JW P'!H%\"0>DA-7AL%&S7*/C(*-BO
M4;!&P3OTR/YZ/=)%OKM5R >#9:TQUECY]%@YJ+&RQLH[L'*PC)55 'P39VI<
M $HLV\VK@+!D;P-NG,%WB3@AJ$&Q!L4G!\5A#8HU*)8R'9O#H-FEKO6D/*X)
MW;Q/DZ-_+F"C)K%Q0FX3R-D20G<;$YV21<IPA"G50+?C0!<T:Z2KD:ZL_I'8
M!?T780!*X%&(*/4Y$FS*\B\.N3Q$72S9S>R;&QZ(BA@,RT[&UM>IAJFA\]&A
MLRZ'J:%S W0&%>@<AV7H/ GSJZ,+510((??#T1I":P@]" BM"VQJ"*V$JSL2
MKC;.QR$FDK?)^1@T/RUY'R\6\_F40#*< HP6@(J$F,OI.B6?HTT>UZ['@-MW
MM@\%%-ME%D0N&^K4H+CSH%A7U]2@N*JZIMNVH!A0V6%OV&Y^_K.]MNRP8GEO
M@DI_%2)V]KVBYD+-"P'%IJVJ,<&FK]0<L,;$1\?$NK:FQL0-MG8'IY@F4:C1
M+UU?<G@/4+R/^MCB[,#A\]U'RQVRJ>L,\$>'RKJ(IH9*#97#+F7M!,W.H-EO
MO[CN#H;#GOI\'31OAMJ27H%N#(\G5V%R2724)S#T+)V".@6;33F.6UO7!E:X
M71X#2+X8Y>K/!<#L]-8+Y0&KR[F#/3#'MZKG#DS+K*;\_<N@M*;\?QS*_TY-
M^5]3_G]3RO]:!?K:*E!=!5>K0)7TO4&K-1CT)'TO&"Z%$=Y^5N,%:1^;*G[7
M*#E_#Q.TDO[ZEZ#7?!5P[ML>ZRW&:\838M=9<^!VN./?].47M5&XZXA85\35
MB*@1L=/IMIO=H(VNM)X3: VP)"YHL<'X:=N@PCK@]%<9@5)"N^L-CK?UD;7*
M(=9^S>NZ)W!8%[W5<%@)L?9)[H8.'/80#OO--L+AGUO'$[;!0]$7/6$9V'TT
MW,K#U5^B<JT;(.\^%-:E;C44WI6"%W37YN"]3Y,_3<';&SS2&?P!^T^I).>.
M+G4FWC?)Q*NQ\='I_^OBN!H;[\S$Z]\O$V]+P*SS\6IDW&%DK&O?:F1<GX_7
M"JKY>,4V]O.6T$CH5R_FW]9Z%%K-I[\AZB3$[_I^J O[ZOMA%0]MJV5Y:%OM
M\')64)$T'&8XT^)7,$7/(U7<*+@7'.\JGOQWBRQ*O9]3^'>BN\/^?3$%R[K+
M!*U/CWZ/IA\/7/U80+&.M^\^_M4U?,N+$W1W'/\V#_!15+IV\&*NX+Q?PM@F
M<7$%0[M,5)1.ML2^#_AE[V?YMD8_XR 8"*_#$P(@97P^2D")R1,I9;K6^_8$
M]SHU[-5J7ZE#-/X[: U?1(-VI]T+./]RV1M0C0J=@.GO,N!HJ*OV&ACZ7CA+
MDTL'*'W"E==A\BG'/Q%")& \1_[_W]ZY/Z>-)''\7U%EJU)VUL'22 )TJ=TJ
M&SMV+JR7-4GJZGY)#4B8J0/$ZA&;^^NW>T8"\1 /!X/ G:K86$BCQ\Q\U-/3
MWQZM)B+1@B_.M+O2!>R(?'+[8B#"*)#B"(T_R)/AM?R[\8<?/' IA E5@9GC
MPM' A:8GO1+R(&1NJ;A69Y*=<>[Y$50+#U6;H$I0G8*J"3^!I^>N73$K%5M"
MU4XR<]=0Q]-*SBE[=UVTO0$0;*5U6?-ZO<@# ^S^+>\//US!D7V!2%#LG:C7
M=*:= "[P#"$*!!&X*7"Z'##:PM)].!B/&\9!&'/E[>4 E;]CH+PT ('_'8$"
M)\%[6A1X/,++.Y47,W$2W_DE- $SWLYXX"E!H6Z>8:DO<<\O>8/%]U!\/K]8
M.P)6.E_&L0[T/BGZ^Z1<K/?)M+2000G)%MA3_DDOG+T[;RNS(6&F2D T&Q*6
M139;D\Q9LJ?ZHG&LPQEQ>_L!:>7I:36+@G4/A-R58I&;P+QW,#OR<R4%,ZOB
MF+Z,P6A,,;GN1>A>G7.D2!LZF3$#4QKZ.';_'-A^K5U.@+L!8%M>F\? >M@+
MR@_@6S^" L2I-O CK0\7$B!@\10G K8^^G$/CX+&VA]ZD<!W MB671[T.W%/
M$QU =JLGVK#-%6&[YX>>>P!0SO-VRSI(9OJ<64N:/#/%YW&5>/RJ>8R). U+
MG\FU5*E4K?..7;4KNLJU9#R*1;Z9.28GXBEVIAF.8\U!^9*/ !VUA =8P@DN
M.@E7/M+^  *%9Y+8RGWRYV#TI#60G+SMQ;+9)-^O@<L7?/: RWVR>DNYG*!F
M\A_PEC,]$<A?'N1.L4!.+I&BD]YR=)2"L+)QWF$Z<^R$]$]B-.L+F?."Y''?
MDMPOK\']GP9\,>WA+&3U\B:0U4DT4GC(FGJQ($L,+2A#V>8$G3@S)4/G'1K$
M4&+H,3#4((820Q5#TV 0IE<-IV*?NZQL6S93$78_TA [7%].0G02":$"[7H>
M#[VY".)D@+N:GV?)IHN;]-.MQWM1MX9NWGJ])H]67RCVP)Z'SMRU)M?6< [,
MI@QCQPQ>2E2]G435]DSM4Z)J2E3]LHFJC\)@8F0PD<&TAL$D?J3+\\9!U-4V
M&7QN;CR1(?0*#:$C :I)0'W50)V/0;+Q,V.3X%#+Q.!0.QN&U!0N# M5+-*]
M!X5AI:\"*_JFF%HXR,Z!ZH)!YP%S=9U (5NF68T?H+%K=K*%J%ET:I(PEJBY
M.!] "&3L23 &*1?AWIY!34F!9B1^P B8+YLB,96<?HZH2VRUB3-O&KB'BU3*
M-'#80"51+ %U:0;_),N4I2](XP]C_#:25!(3%P >+0B03U+JJ634E9P0^:_-
MBR3I -<>NP#FD>8_#CRUQJ5P!9;@=Z:R$V A5_R;B'A!C-*7%$S1T@*O%]$%
MTYD2HHN!:&9D/ 6&S/_W-/#!:HU$V%> OGYJ]^(0!:&I6E1*/E=$4:HQ<9)%
M>MYA,*-INDM..9F>)A*O=#Y4QBHE5B8.'PB'235*'%[%82:S2QN1WU/ 723H
M-])TW<_#LS+?C*7F--&9Z/S*Z$P:4J+S*CJ;DLXL\A,[.3?="M&9Z$QTWB*=
M"R8,+0*=#59P.B^_P R=PV=-W!GR<S87EO.= :^SX0Z+<]HN1[#*R"(GH.9#
MR(H,8'C>FP%X-VEAM@%M9F2B+:QD"U&[X-2V2&E*-G7N@EJ6T0J$^^"U)SA>
M*SO+S#(L*Y-F77KBQ@.2-!]%]'^X#=QVTV_=3J8*WR^:*DP..]/JD7M0DX,%
MH3HM+';,9"?]*Y$]G^SL ?HSC.P]CZ?T5FB_2;>G,.<2:/-([W/72[FN%I:8
MXG&2F3SE_/[Q3#!\Q3 D;1O!<&IA"(2AZ;#RN5NUJE4#I6V.DZZVTT6;K!%#
M.7PZ_?9/F;=DIVYHIS;;7<^->YYFF%?2(YS$&58)NP>"75+ $7978W<NB]4X
MA&(5B<?V67F&Q =LD!+U#IUZ^U6PJ80=!+Z"@&]J\%W6Y>"['"0373Q%GB+@
M>/YK0;S"*A1.%L1FUHQJ[8!AN.DRX$J?EAKH2A%-S#P 9I)(C8 YO7(C8T:9
M5=FY"W\Q9JJ5&^VE\T_C9 A2$*4GB5*6#\XO<$';_P(8VWPF[. ;E!@'N%9
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MN5.0Y,2BWB#.D#@DJEI "@O1!L@WZ$2C7() 1#'3)82,MD>MR$8-V*C?=_4
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MC>-?5CCDC@C9Z/1O]"*ADJ#5FZ'164-?-V5C ]:7$'V&84-OWBED0[UO0X]
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MM$(<Y#P*/Y![,O&=NY<8D.2LXM42! $,&U]W8,S&!MWK,DO&+X@V;\Y4T1Q
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M,;%HLA(EN/(?!]_KY$R4-D'2MH!*ED-(28 R+ALL@7[%5P^=#K,_OZ]_Q+#
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MT3R@+ZX 3XY&F+4&7S1"]"A5$HDGC5U&> '&Q3&=(]33,3V:CQE'TH>/'WW
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MIC]NG<W5[^J*7M2?<*/9U<@39O+66:$5K1AWX%,QP*U+W@3+I;GDAE[-PO0
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M6+"%6U Z!G+O- .3B\U!6V-+GV/37T+6<.0GYZ"6DQRE8\S)NC420?DLP87
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M#@63A)@+!^6);-%;!IKB 4X(K>&B7]Q^BZ?UL(%9.ZEO.>>-?>L)>3/683+
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MD2;/$OYDO!*HE"F=;N)H 7^?;/!7P=O["W_G5^1-F/+<%NW!HZY."LU4L#E
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MR;PY%70(P>N2^CB?]P"[3PYH1ZKU%N.&F;7UY_6/&!;XM[_\/U!+ P04
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MK>"\PB_?33XU7\<#EI7&I882@98ED>" ..<2852!B)P*SF-_BKX:^+34?*!
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M'5I=E1^#^_1^5$N65"+H 2IN<&?^"TQ'WQ!W0;6>7C5;IW>\^EXRAT;C3W_
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M6$)97YV[B'.D+AID#&R#QE?0*-7*0Q2$\<B)Y(JB60F!J(B@(6AK19MF?7M
M_6@T.407 ^TF8@4-E)->2T$R@$ &2R#>1$MR0(?,,AF\:'-]M ?4CT:30W31
MP&Y^9NB3Q!5K0W3,E,@H''J.";&A7TFMS9DEW80GYSB([SR\L6KZ&GXHW_/8
M?@[E.U"7_8;R]5?$T$/YE'.< W?$0^E[8[@B@<>RV:HLA+<ATC85SB]M*%\C
MCO21_^!#^4SIJ*VL(%&D2*1%17H1(VZ?GD6;!=.N#3E>TE"^7AKL-92OC_@'
M'\H'U(#6:#[I (K((H 0#:!&([C,*453JUNFQLL:RG>(NNM+M'%KC )O'9NW
M-!NF(E%.!%RO1>=*@$=H20DG2]9^FZFMV_%< !LJ"GRGFU*O7?W]\D</8FO+
M7NT?X>_YK;]YC*9;V_HN'WML^_K>T#?:V$MT%)6"J'@Y_5WR^+6TK2D-Y6B,
M_KK+ ^H[C;/U/*/?[XN^J1=ECCQ)6J%Y0E,H=*%$X,$1&>,ZN.'FN#_%5\^"
M?3LI'/ W5U\FM^/YM="",N\5@5"Z"066RHTU[J#HWDGKD@'5YA9N%Z)3;D_5
M&++;@#U"_"WN9S<:4#V<'[>6P,?)*[B?,P7IE]MR1? 67T[&_X7[^>?9M8K*
M!8<[;!2E%XS0G 3#!7['( 1&M0Y-RR:.Q'^1E#N!:IMXWF%^+Z)'YWT9QIG>
MPS3B+_PGN!;21D5]( R-0")]F<0)Q0B(8-$),%[K5GYX5XP72;1&*AKH_OA.
M&*^^EU<#Z?\'W"Q:3\T^C[Z^^KZ<EW<W^?7WR7+0WJOONRX[EM>FCBE0GB>2
M-6[I,F=+@F"<B&180)/7"=LF:C'<&H=J[C/H\7Q6Q#B;MC[WR0]W_=A>ET-C
M<;&G7/01T&W+S#DBV:*P$RCZ<\KHS$0PJDW@92^L4T5>SI5*NQ/ECE1IRW#P
M_J#5(DKUYW@29C#]5B2RB%CBKR?CB/_52H:/EW=WZ?#\ H?)J6NUQ)/GX1U+
MJUV$/2M.O$CRTPC*NNB(\K8D6FM)? 9+,A5):B],:%7D_C))WSTU\,5QO@\5
M&G#]]\GX4RD-*"[$>K1XT-GRP GSW",B_,X+$8BA8!GUBB;?)GGP*9839OF<
MA\(W^ZX>IZT&UU<[#*?%BY=-YI1%A>LKY22>>>*2L40H</A"6BYH&P]L#ZB?
M1NE>H[26.AM<'>R MGJKNH!K:D[NA7<:4[":,KN1Y A--(D$[P690+NH(@D!
MO\C RP#V+%"O-"F>C#"YS1EW IH\8SR=B"4]%-" ':O]]A>8C3Z-[]<;I$\I
M,"#2,EFZ%Y7NZ &/:L6REA&D MN$%MOQ_#RL]AY6%938(*WU*:IU)F4'7$V/
MJ%W(3G,ZU=#>LX0X0O2#[#IKGT ''1QRWS%GB>1HR5L$2'AP6MF ;PAM4]$\
M+"6>.8F&9$0?B3<)JBX!0;J:K3#>[XXKSXXYX34/A@BPZ-E%[DKUB".0DU?*
M28>N8J, UK/@AG?,ZVCR2=2IKAH:.-AO)^-TAW)=*\8H50;? V$21^-)E(;:
M%HC0.C!& _ZDS7:Q!<R%,.%8,3<M>=B2RV]Y$. 9)=&49HE(T&(W1>(D3Y$R
M9K-KX\"<8ZW5"[%7JRFT8A_,3@G"7;#]+,8Z4)=]"FT.4<30Q5C:">$#!4*5
M$T0FD\MPS$R$<DI*Z7#S;)-K_[**L9IQI(_\VQ1C_>6G:;,N1//,*%>,2$_+
M;',KB6=E))Q7V7"FO,AMC-GM>,ZL J.7SIYFF1XK\-IU5QN)KU?C]*1N: W3
MA A,&8[>G*/X&GB.-A;*("@I:.D7[L,&+W948'5_Y@7HOJ64AZO*<CE'QETB
MR,9B7Z.1[56Y;&9,N)BS1!'\N%59Q^P)%03>)/GW89KRXA1,!L 92"2D,BZ
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MHB\EVD09MH"Y2#8<*_0&T:G7B[RSW\9/R^;?C9=QC[+LW\:/ QWLFC)GT-.
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MOW\1C^IYN2>5N"F+NY(\7"^5Q5UJ[KI^*);YPI^%2>PKNL"01*$'4< QI%[
MH1<A&094V;8XL.$*PWZG1AVUV*!<RPT>&\&O .$\TZ-"YH"LM0"D5L..5$R'
MQ(QC!@!Z8,II,-Z(#&Y6&&^D!M?=P%HSD"5,O1*2:=^C\I,E(/MT97N[&WM=
M,[9\6,[;K?Q?\U*0>6UQK?<*?E84^;&HJE_$ Q7E+ S"($A%"$,AE<D3I3$D
M)$$P()Y,@C",8DIG3Z*DA2F1V8I@\Z)M"S+<^W;]1+*YMDVA+$I8$;6,J@1;
MELV*Z;=&;$O#R'I@S,AL2+ '9K7KSV\^* ;;* "TJ."5%O:/>CU*%^!V#;NZ
M\F!4KL -*?6Y\MDAL68_5UQ[I4%K(4;E0U>(]HG1N1T[AB0/=_GL\^)>E&I)
M^EB*>Y%7V9/XD+/B0>C6Z]^N^5^73:=4J,=,J"7G3,A(LH2$, AP!)&,$HB#
M1*H!$ZF0:1H3$IE8>LX23,WFJ^4THS]WU+OY;Q0L!R; 6D2P(S]H%%B38'/)
M1HTKT"BB-^F&'@#>>NW42ZN7'8@=4?[Q!L1X]KD8S&;ZT<W4<XJ7AEX]H[@W
M/,J4<K'>JSGE\H;<S.[W)"OK@[=?!*F6I:@/K==?_GLF2M7D_7.[%T98Z,<T
MB&",HA@BBM6$DG@,"N&EA/L>C4AJLW5@U?O4)A,M9W/J#-:2UJ<4GZ[_RW$3
MTFXTS SMP3 >>)*Y#%YKN]D)IEZ-9CL)1K68G<#9-Y?=&G&C-66/;ZASYG,1
M2)10&,<)@BAB$J:>%ZL_E7WLQT1Z/+#;*MAI?WK[ $H\D-7RV?'/+FP8!S@)
M10QE7&\4!PFDZBM(:.2'H8]%Z/NSQ=I?;3C0%B=<[Z8'&0G\F'D!A52MKB#"
M1$!*$8$",Q*'$GN449L)TAVR$2; #61 &2. DBIC-4/S;+[4VR+O;FXO 5.2
M2+V::M$:!PI1%,H 4N[[D"."?/45CT4\6[DI#P!EIXOU])X],W/ ^8D:>+K7
M&.PL6<#U8E%F=+FHO4$61;MEUM^,?Q2)7F?TW1Y&G;&/*K<_(Q^_R&[&Y2*;
MO<L7V>+YW8,H];GFSV7Q;7&OES$D?Y[%/D<IB]7\X6,"42(32,(P@4&:1D&,
MPH0F1J>-9_J9&C<VHH*5K* 1%K32FKWFYZ#M?N%[!&S@5]\1*^,7WA")(Z]^
M)=CKN^+I1]5"\]:K#_7+7K_FY]H=Y84W5&[UZIM>[GB(M]Z?^%I<KT_1;TC&
M/^1OR&.FS+B&<+Z2[^^D%&SQ7BER>Z^8_2=2":ZE$'E5[Y8I<IK1,$HHP9&R
M (2V #B&:1I&RH3W4H_%,28)LC&G>I9O:J2C'2 S-8YL 4K1G$RI>5,\/,Z+
M9R% I0]RH8Z>XX!M:0+$=_W9TOCH>ZP-CPU?;@2'/E5<:Z8';:,;T,HI\Q"T
MZEVMS"0]VHV*32QJK60[O-MJ7@&E:(\'C,.,0+_GCSW+..[QY#  'YQ>#M2-
MX\RQ.B-_7Y2W9"XVY^?Z.'WSUYMEJ5<!LXC@4$KBP220>F\B(I!*QJ D4@CU
M/?%B;.G]82?!]#9]FBB:>K6T<?JPY'3+43#D[.&0'9B3C5PY6K%[9%@WO/IE
M4$L9QF5(-X .&-"Q&3>&:\CT=J',,DVZJY0(U]^S:L:E[Z. <,CBT->!9022
M.%+CHN@L(4F*<6IUKM;1U]1LUM:86<L*5L*"W[2XE@=H72";D55/T U,3,ZH
M69.1 1Z]$D]7?Z.2C('B^X1B<HOC,7V69POQ,7O2WF4+]21D6P%(:R^TZX>B
M7&1_;_Q>4.*'@1]*Z'-?* O))Q!3GD(JTD3$*)$R8;.#7!3GCY.M);';:^],
MP='K>FO+?Y-LB6MY8F\_,&8\-!#.(YW=U\+#6GJP$;^-SMSUG;TVP=[^.-\9
MOG[/].W%&/=@WQFF@]-]]Y;L*+$J%[,OJGW1NIM[?NIA@GP84>+K#"0Q3)E
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MLU36[O)A.=?O>.T<J-?VI;A7R_OL2:QLX)VW38:<1(0CF H10235VAHS*6#
M_2C&+ T3;!2'T:]84V/??:TJ'95;,^=&,U#4KK!L6[=VH6Z;X[:7D37CT?''
M:V"&W5=H-5);.C7Y'<".5JM%_Y#DVR_6/>?8[46TD5/P]@GG88;>7EMW(_E;
M=B_X<BX^RQUGO]WL9[<+)4_]25V6Y21G&9G?B%(9% \Z[]EUSC=?%TU*](]%
MH]4>9P0Q2["(,(QH0B 2E$%*.(9I0&4<"(\'7F@S&XPL_]2FC>WLD%F^975?
MXAC^4L^&V7PRX1$?>.)9::XGFSUGZ;WLGE=@ T!]]4I7L(5!O6+;^J6%X0JL
M@!ATJGJA8>QU3AM;AU$GOQ<:H/U9\J7$< ANVDZR]"%?J%<W6Z=;^EGOFLR0
M[TG*? D1Y1PB%@I(B$>A'S'J,1P0))AQ4-/9[J8V6=5" ;8*:2)U=+I%0,UY
M?+MGD/Y1&_KT<#OAW$;85>ZY6MQ>\;,(1.H5QY$"D';PS#9X-B&WS<YF7VFN
MC?'I##<ZW\IX84;&&NV$%YG?=4$X^<\B%R69OVO<V&9!DB(L4@0E\1E$,0XA
MB1"#+*11*M,@8,0EF'RWE^D=<CKD&CV&GID9?B$B S-GL__2B@?>G7%O=(L8
M/ZY\__'B>_V,'RU^7-&CL>(G+K7/@/ZVG1'>9Q4C\_\1I'ROOJEF&#$9^"*"
MD=2OMI\*F.I-!#\2*8M#$0>^D075T<?4S*:5F*"1$VA!02VI>3KT4W!VO^L]
M@33TB9<]/E:YT<\@X)0?_52;H^5(/Z/4=I[T<Y<Z;CPN:27^ME3MOGM2_WQ5
MK;PM'DB6S_PX82P5#$JFBW@E0D**@Q2R"),DQ%$L?*L,YR=[FMJ+OA$4U)("
M+2KXK1'6,M#W-+R&NVQ]@#;T?I@;7O9;5>>PZ'=3Z61OXV[_G%/Z8*/F[ V.
M^4V/)*5:F:H\I;X0",$H(3Y$%$7*&D >C.($2TQ0G%"K>J@=?4V-+$YD33MG
MZEI#;$87/0$W,&$X8F:?</0\&OUF%^WH;]Q4HN<5/\@;:G"+X\Y >4?R[.]U
MVYMB3;J@<\YOU&.UVF_:VC+>[".O2]P))!(?BQ1B++"BF)3"% <,"AIP@B(:
M<BYL**87J:9&1MM*78$=M>I3IFW%=L^CMLZI7"LV]S/.AKL>8X_>T/LD(PV<
M_0Y+GT#WNR?3BV3C[N+T">;!OD^OC;]\X:VW0HI2_?B5?-_Z<88][OD^E] /
M1*#F 9_JNEL,$H]BG_J^1P,K4W-XD:<V20Q47VFEO(ZFV[[BY8ING7B"S&:8
M:3T7 T\_4WDD7K3@5O<H3;;>U@FQ_V'+;74/PY#5ML[T[.")\CY[$C=%EB]N
ML^_U9Z%>V'SQJ5B(ZNU2!!X*VE1_O@RD\)B &/$8HM#C4!>8A!'%(HZ2"'NI
MT?+&KMNI34W1ZSCZ)Y!K.0%?"J E!:^:;^O/M0I_M$RZ:#D4W?/#<  /S/%:
M3E +#934H/FSD;N!%;Q=(3XHO#:UZH> >:P:\CW";5G8W1:U[H+KQJV-6 C=
M5L/= N76=SNFX6H".=M%U[[/S4PF,@FP%\*(, Q1$,9J#>-A&# 214&0T)1;
M%0#K[FYJ3+\M+6#WI-0E1DA5%6I=J@-WZ@SK,LNSA8!S-4C\T$_,,DM6]VB8
M+0KZPWA@LM^!MY"'3HL]II\RPJ3?Y%'=78Z;^LE(_8/$369W.1[IZ_1R7\2C
M>ICN225NRN*N) ]?A#X$U.4/UR5'-]<T%:K\61!%.N6M#PG%FI00@80G")(H
MD#1.)0[]R,YCSUV8Z3GVK>IXK:)]Z\1N3278<BV]CLE78P4(H 4IU>KX\;$L
M-('M7P@>5>.6W@3N(VOH;C#*: WMCU #O9$0M&KH'8U6$;#19/O"ZVY7>'N/
MA8OA[->EP5V<<7T>+H;MP"GB\A8O<(MNRW@WY-XN@V1 />0'BEI9J)B6! 2F
MB<20,4_X?JA6_,3*N^I41U,S_!J/X-TB6XY%%$YB:WB&V -B0Q\+-N'K+5C7
MAF"YN5%W(-&_+_6QSL9WJ.Y0^:A7==?U+KN#ZCFI%Z*?LEP<7XGZ[1,M2.!+
MFJ10\$@7*" 44B]$, T0#X)0/4C,Z-3+LM^ID0=ZG>[O#_K@5?-M_?F"_4'S
MP3#9(!P$XJ%W"%5+[9:5%KMCS\H?&&&;/<)!D!YKD[!/Q"UW":UQZ]XF-&]N
MQ'U":QUW-PKM;[\T^<>'7/OL%N5S.]7L96:(DP 3Y%,8$%U+.Y+*:$QI B4.
M4DY"#R4TL%R>&W8]O<7X2EYK%P-CM V7S ,@./0">2N!Q5KHJ[6=.4ZZ"3.T
M!LH3<:;S%TKP8 ;)Z<P,AO?;D515+F8WI%SDRKZ[SQX_Y,K0$]6J1%V*:41Q
M3*%(D5#+V"2 *?83&(98>#3U/)G$)H9I9R]3,T,_9@_9HJ[ZL!;8TB#J!K6;
M>'J#:F"6V49G)62/5HP1#%WTH1K8H@[UUSYM=/<P"D<8*;DB!+.+79-0'JOU
MUP8(K!:IL1?&"5(O/^(4(H\QF(8B@(D4) I9(@//,L/DV3ZGQ@PG"UJV4CON
M=)F@;V:M](SIP!1R.9P.J1N- >HY+^/Y?D=.NF@,Q&%&1?-;'?;-OBK@&P\.
MO4([NC +O/:MH$D:!!'#,*2QLD^\D,,T3IG.>DM0*''L"?.-,XN.IT9,X6NT
MMW,6>.!5\VW]V7WGS&8X#+;.!@)Y8*:JI6ZW<NI=G9-;.0KK@4&VV#T;".R1
MML_Z!=UN_\P!N<X--)OVQMM!<]!R9PO-Y7XW U4G(Q3\L*!%_?V;)I=OD[IW
MIV[0C*<DI+Y.!8A9!%%"$HA]@2'U$ I2%. H2NRVU!PEF=X.V_M-%ENR*31G
M9[FZ#@N+<,"2*($>"A.(&*80ZSW/$'LL1#+E* QLUA(C#,H8T_A&TC9M8YU6
M]DBZX:T!:U(/"PX6!5C<B_W$CW4+^OO[&B(P=PW=<AUJLX7+" ,XL(G0:'"B
MV%+]H]Z"78_OD9)U_:UR+D2SUY6/JRRCKH8N!&Q_A71I<XZE[%;=_/2\[OJ-
MSGU__3VK9L)/XCB)4NA1%"O*Y5R[%X10HDA@'_N$22N'],[>ID:L:PE!+2+X
M30MIN4O3#:\9S?4&VL!D9HF7?:$X$QSZK0C7V>.XI=],E#^H\69T4R])XFRS
M=9RZ?4+/\WX.LV&R:9P#8L@$9B^4\^*<RF?2EPV8F>(ZY[4G7QT3W.2BMWRN
M[1J=T--^+-Z_WF.O90=;P@_R&KCA-G0$?I<(+QU-;P"/062\22L#[+[,6)@$
M(642)L(/(>+4@UCB$.IBR&%$,0GM#@8[>YN:97E^V=?C,KN/Q?2$>.H"[/I=
M$H^_\)W0\M9I$7O) =\Z0EM_^#^B+-I-XYMBF?-;]=*J&^^V=I#C]N C5CS#
MDYC"@.)4EW6)($5! ,.(!S@*8IX&1IN&EP@Q-?J)7D?>/X%__H,?AW]&200>
MLOE<S^L[1X&Q3K*AKZL_/VH-0=6JV$?.#<MQ] ,_8D$:0Y0$'D38YS 540J3
M)$IY&$N!/&*V)S_62(ZS(7]FC,8<(H.#W!%@'WCZV<KA47_42JR/%VLUP.WN
M"+Q=O4\C#H5+0I7AAF3\]"J]#XUCNA4W3,V2KUBV_0*I6-RT/YZ8Q;&MRW8&
MMA=%>K_6PQ1Y:11"B2.L%BTD@-1+! Q3/PJ9Q#XQ\QPZT\_4[(7UUL#N)H#]
M;O@I7.VV5BY :ZP]% N@G'=*3L PR);(?E\OLO=Q0N%3FQRG+G=8?-QFW]=!
M7ULDM.&=$*\F7D_=C1B!B!()$?%2F!(N(8\#&J@%A^<GB?%RP[C;J1%&_#KU
M=CT+0PQ>-=_6G]W7#^9#86".#@+PT*<2V??M\- =(V?;JE$H#PJOA8DY",PC
M&95]PFUG1%JCUFDVFK<VGJ%HK>&.:6A_MYLQ^"Y?9(OGOV1<?,CKHL5-0MDG
MD2_%>Z70N^^*4G,R?[.L%L6#*#\J>3XLQ$,U2PEB@8>5D>BG(4121KH^10C5
M3""3"*,DELC&7'269&KS0RLST,\#6$D-5F*#W[3@H);<TL!T'RLS$W24$1AX
M ND#?&NC]6+@>C5KW:49U?"]&+1]T_CR!MTH] VI[M_/BV]M=?A5'$X0\% D
M/O0986HUC1DDL0AA&%#FI2PD08CLW*R/]C.]/5LM)I!*SL:_UC77U7%4(YD$
ML2Y<+]0G->FHF0>GE$ /^WZ $U^P%-M,.A=C.HH/]"ZBO0)J-C-<#-/ K%\C
MI 4$K80#Q$EV8M K@1_O:51R[E1VGWB[+^[%O^)M5BG)%YFB<F[L9X_#D M?
M^!"3@"H*#A)%P32 W!><(1*KGZPV-'N0:6K4LGI=MJ,GBASP+=76$19U5(6:
M4G6H_661$DZC:<94(X_1P+QVZ ZRK=!TPBDN@7E(#Q,GN5[2#^42(,]XJUS4
MM!N)OQ5E]E0W7'OAK7O])!9KQU.41#Q)&8>IAPA$7D(AY0&'B1^GJ2]CE'#+
M#%\&O4[/:CZ3I-X97C/6[!FR@5EQ(VWCOKOM)'?5IK36VY?@LY2U=^\=R?)J
M =X4<QT76)+Y($Z^%B#VRGDF_8[*:19 ['.6S:UNG'13%DP(7ND=@5_(8EG6
M@9\WI7@DSTUER)R_(?-Y]5E>K]+>OR_*6S(7MX*UE\\DP4PD>CBD4*9E("6D
M0:CLRR2*62(%3D-NQUJ]R#4]7ENIU6S(/:P5TS&X#Z3\72SJU'O56@4["NQG
M-,U(<O01&IA&=X=FH]$5V-*I#I*HM=(C]E;0!=@HH\AVI2B410DKI6I_?-HK
MWKTR;C^2C<K)O8*YS]K]-N[@PO#?=^*)M#M:+$GCD!(/>LA#$"4>@5B9D5!Z
M?N@A1"G&H;&3PE;#4UNZ__?/[_[K^I__X"?HS^ 5%WE1+1\(=7([V(:OFPLO
M 65@.JOQN%1[BW-_1Q1&.MFOT7C=TV']$54[C^.WKQ_OP/V(E#M'ZL=^=RQT
MUY167:VQ?$G\,/8BR )M#"H;$&*=%3*6L3XA9T@DPLX8W.U@>E;=]>WMNZ^W
MEO7H=D$SL[G<@1B8;5:E20981Q[7N=]Z<KM=C%L_[JAZ!_7BCE]UZ3[4AUPU
MN%S9).WN]S53/]4VB-XCFZN)M-Q*BNY+&074$S"(6 !1RC$D'&'(N?1IR)FR
M,%+7#2I[<:;'!5N[,=E&'=>=+(<!LMWB&A;T\?:^MO2H5VFKLYR-*F"C"_AM
MD.SV?: ZT&:8@T OM$OF#MWI[;,+VG3C6)V*OSU!K).P9#(3_*?G-T5>,_B2
MS-N5X?-;LA![A2<2)*-0>!1278 3^41"*G@ 6>0G:9(&#-/8CF,O$6=Z'+M)
M3%AOPY"#71==++C.?:YP(Z5F@79'[5G]LD8"T&? -@BLMN.>[<CZHI$V(^NQ
M1F]@LMY2 VSTT*.PI<EJY^T9:%T&K472!ZR]LO5% HW*UGU M\_6O;0Y0'6#
M=]_9?,GK^>)ORZP4_$->[_#IU"K58B90("(2$A@(II:[$F.(O51 %@:4)(%Z
M%;BE07R!--/CZIT4_GRC3H\%$,X,D!G'C@3ZP!1[MF#"J[4J8*6+FA)!JPW0
MZO3H%],#J.,563@CSW2*+Y@!9U64P;!)-W;]N2CXMVP^5SWO5[H_MH!-0DZ3
ME'A02IY % H!4T1\F(1Q'! 4)W'BV?@IVG4_M7.-E?3U&UW4]8"SM19M_60[
M+K4<#C/Z' [D@1ES!]^-Z*MBRX-O&;@!URLK6HHP*A&ZP;//?8ZM.+O4/(IR
M\7RCGK.%ZO&=8M2::V^*><:>-V]6&**(:>>^"(4ZB#Q@D&#N0QHR*6*"*??L
MO6:,NIZ>F;B2_ H\:MGKMU&LI+\"N; T&(T'P8S>A@!V8&+;('JS1O3=!M%&
M</!;^]]!N,T6M;Z]4LPZ']OQQ J2([XE=O?;<1@761LX>,UYJ<T_]?%S^;7X
MEL^T[26\A,/$\R*(>**#S0(!B0QE$(1!Q$-N8I=U]#$UXZL1$[1R7@$MJ<(1
M:%G-^*@+T&[JZ0FF@5G&"2%C(C' X AG5(*]OBN>?E1W-W2A/M0L4?-#5YNC
M4(&!4JNWWN12^VJ^375@]ERG8TI#98$P7\(81_JM3CFD!%$H0QS@F.J\BT9Y
M"_8;GMJKO)+-*I?5 5K=K^PE& S\GIJJ;U5^]YBN%U?<W6ETM"*[QU39KJM[
M]'?7S>8%R7+!WY$RS_*[JO6UPR3T$Q$*R#A%^D44, TC"B.9"!:G:<R)5?F5
MX]U,[;6\9JP)MQ)Z=UAF+#.H$6T#J^GN[Z5@#;ZQVP@(5A(.4OJV"X2>-V*/
M=C7R'FN7NH?;IYU7NWIBT<7&-:&MPA2*.(T1%#(2$"5,0NI1 GG@QU[$4H$\
M84,#AUU,C0+J*(J-B$[))H\ :?;B7P;/P"^])3(.[DJGE._9">F@FY%=BTZI
M>>@P=/)*ETR2[%[PY5Q\EA^+_.ZK*!]VVZ_>?6?W:KP%W_,*P3(*PC"5,(E3
MI N3<K72#@G4;M4>\T+!D45B24<IID83*SVTQ\]<:0)5IP_;/I9 K!2QR8'H
M.D;=]#(:\@,ST#;H']>@[_%2!=:*V/CK]#@8-ODI1QB4L=)5N@U.;SDK+T2R
M.X6E:^,C9K2\4/_=!)>7-N:8K*UX>,@6ZZ#$.B'&G5KGGO M9[[O<352T-?!
MWDB$&%*2,$ACZL4R3@+N,<LL;E8"3._<:D?B^HR%;32RS$AF-Q9F]NUP^ Z]
M8;41O FZW@%Z\&-Y-]SZS7MF)\*X"=&<X#G(E.;6BF,-TX5JXXMX5 _H/:D$
M5SVJ-;WV=7J[U"[B-Z+,"EZGUYCAE(E(^#$DB9 0H32$*4<!]*(@3>,X8*&'
M9KFXT]M67\W7XA8B&+V):?,F'@@RY#;42OC:\UYS79&#2NME1W8VHV'&='V#
M.Y*!K:4&6V+79-<*#AK)02/Z59/2I\=JM/:(]5N@UJ+_<6O6V@-S4,;6H0G7
M2*/=)&4?\FO&=,ZGZHM@(GO2YN*,\E1&F :0H"B R)<I3!F6,*:<A2'SHS04
M*T(SXS*3;AU(;&#^^EH2+D"YEK!R<"TR MR,LWH#<:P GH,<BMIY?"4SV C=
M9Y"..40]!^,8=#QRT(TY%(?!-1;WNA'1+W7^*L5M7T1]GK?O:=D>R 5)+%A
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ML-.IV8AKL>M])%"M!0<0;&1WB4(Q'04#^W  ; ?FHPVL6F2PD7DD4"WLQ '
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M!C'E"8S3B*>"4I_2V'A>-.QT:K-?G=A3M'(#LA8<U)6HV;;H%L1I.@(&D]@
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MHV@O6O?E,CC/E8.YL'7[I"QOFGE([XY+J8CK1I19P3_+:UX\UFL*O5F*XS1
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MPL#,;:B_\7M_4M<CUF,EV.N[XNE'=4]C/*H/]=M>O^F'+8WR"I]48/5NGK[
MP=C36Y\?U@7HO@@N'FHCLC$J_Y(M[HOEXH8\UZ56Y"_D=_&7>Z5$LZ&FUIY^
M(!E6;VDBU-J3^Q22&$OHJ65G&*+$"TEJ;/9=),K47NOZH&*CC4XHM=)GM:3Z
MUF@$6I7T$DLK!6JM0*.6A5URV4@:6(BCC<\89TC_0$-C83R.-D0CF9%##Y6=
M-=D+NIUVY64]C&=A]H+$CJW93XL7!Y$W>[T;5RE$$X\E)(723Y@^7L,01\2'
M+*(R]=+4%Y39Q3.<[LSF_1LGAJ$5<#N$W-)EK0-:LP.J?N :>$;9"1!?@3:$
M?]AY-(:*#-_O[J6BPD^HW1$1?NH.-ZYH*:CZ6ERSORVS4ORTK-3RN*I$X_"E
M#XG:7_C,IXGT<$)@( 6"*/0D)$'H02])$RYPHG[GLUS<:5<#,_:PZ=[H!4F;
M%V1;B.'>DY7T^N"UE1)L%%A[7]9'MBLM[/C&:G@"&294I#Z,)$G4\*A_2,@C
M2+W$9]P/?<JX';GW/CRCTOW$AL=L@A@*\H&GC%ZQMIY'7$#K=6:Q$F#4N<8%
MFOW9QZD-1]_?C;/:UY+DU;Q>D5VOHPW: PB?BP3Y,H3,$S%$,I(P#6(U$P4D
M$CCV,?.L,C^:=3NU39GW^QY;BXWLED=!EOB;<5G_J [,8MN>M@>>5QNY3X90
M]';:XX9@OTZV9EV/ZT5K!<>!FZS=W>[E(#:YFKZ*[XN?E :_SP)&?8:DA#&E
M(40T#"$-0AV9&T9QDJ9I)&/[V@]'>IJ>'=:F(LOO "D5[G>BGDSL2ST<@]6,
MB'J :HQ-W(V(X#<M)*BE[)%.SN#0>VV&8WV-7HBA0^%C51>Z+G<XD#J>ON3-
MO7X//N1OU!OQK-Z,.L7;C HJ8HH2& 2!@"C!'B0>4T:.C''H<Y:RP+PPED7'
M4[-KVF1'#TVRHVPM_!5@M?@Z"3-K%0!/6@.+PPN; 3$X11H(YH'I9C((6QP&
M#83T2$<_/2)N=\KC %OGF8Y->^.=X#AHN7->XW+_)05W/A]U0=)HMRNLR,,!
M"5,!/6480A2'*4P%YM C(D*(IF$8F<\%QMU.;29 K_U]OU-?%];Q&[]3OX_"
M.F>'PF 6& 3@@>> K5(MGT_[--8H#PJO2Y6</F$>OS+.Q7 [EL(Q1<VL_,W9
MUEZ@Y(VIAL?+W!C?[1@BN\KE_"%_7"ZJC^))S,/V)9!(Q*F("8P0#R'R0@R)
M,O<AY6&4! E->43LM@<Z>IO>%L%M=I?7R674R[#,"UJ)\JG>7,MJX<&K6GP0
MVC*]"?1F6P@]P3DTIZ^SN>N\L%K0*]!"-\#NI $F_89T=O0W;ISF><4/@B\-
M;KGL"/^S?)L]95SDO'I3/#P4^>U"[Y E'N4)YS[T!:<0H11!S#&!?D"HSWA*
MPR1P.[0_WN'TCNG74H)'DCF>\)X U^Y,]P+ 1C[%+23X7/(L)^4S6,M\!1JI
M02UV_Z>WW? ,<EY[HLL7.:'M5O_4F>R9NUS3CCZIMHOR^=B6.V4B96F80,FC
M0!$*9I!P9:J(5#+)! V]V-)4Z>IN>K;*2EKK C2=J)HQ25](#<PC:S&'/](P
M0:3GK)\='8Z<XO.\ZH?Y/ WN<2.-XUMH;S,IA3Y %S^)Q3<AUGMIC:OS=<Y_
MS54?<_U5T\(,B]3W.64PDI&R6,($P]03@3)@! E"RGP96V5NZTNPJ6V.G:H)
M<04VNH%6.;#2K@TAJ)/[;!1LZTO8\5EO V[&?2\QC.,<PXPQ@M;$VC?<O9)P
M;\*-2MA]0[I/[KVW[^S#IQM6S=T4\XSI%'3K^!/B!:%.Q1FE@2X(1A.HK,84
M\BB1)$XPX](HP/)\5U,CZXVD8"6J24B%+<!F5-H/; .3HR-B+CYV9\#HVZ_N
M5'=C^]*=4?N(_]RY.R[*'?FS3DV8UY2UD\"RW:<EW*>8$>WS&TJ(9!QH[@A@
M3 (NO5@2:5?;PJC7J=%(D_/[;BTS+$7CKLJU UFUEA[ M0.KMA.*^C;'O7.C
MT3'<1>\;\X$Y:#L_[_,5V,A=%UI3EPRQJVZ#T1 I$\_T_!(9$<W .)'PT/!F
M5W_?,GNJLY=MA?MFU>]U0KV !K''TP2B. XA2D/MT$<)E(QP+TG"-$D]&\KJ
MZFQJ3+61=2OBW:G<3B?$9KS3%W"#TXT#9@Y>P.?!Z-D5N*/#D?V!SZM^Z!1L
M<(^#+]AM]KWV.M#N!T?=#L*TG5O#./")[Z50+9T(1&$L()6ICL!E(4>1GXB8
M&?N"&7<[-4*)7Z,]7[ P!:^:;^O/[KY@YD/133?# 3PP\2B96]^DVDWII'.2
M0GE0>"U\P0:!>21?L#[AMO,%LT:MTQ?,O+7Q?,&L-=SQ!;._V\UL5*N'HBF*
MF]\U-796!4])$J'(\WTH(ZG(WE<V(Z8AAI'O>S&3B3X9L;$93_8T-7YOEK9-
M_;&Z\)B=E7@:43,3L1><!J;I;1G7I;Y:,?_8GX%X%HI>K</3O8UJ&IY5>M\N
M/'^#&S7H5/Q-Z>P['7=\0Q;:ST,1DJZ,+74Z?L%_?2SR3\MFRA0X(9(G$"L3
M$2*6((AEG, HY)X?A0Q+AFWXPJ[[J9%(70YC2_PKT"H :@W 6@6P5#I<@48+
M.Z:Q'" S^AD.]H$YJ6?$K<G*#;A>&<Q2A%%IS0V>?:YS;,6- +4?6];4%KW.
M^:;;3%2SB(<!93'7^V@2HD#&D"*U'F:2B,BC'N*2VCF?=?0V/=^S'?&: DT;
M\>U8K ME,\KJ";F!^6E+RAJP'3G[HR$#,'KEG*[^1B48 \7WV<3D%C?JN%W2
M2OQMJ5I^I_W<ONH8DEF,@]"+"(&QY&I%Q4(""0H22'4U.4']&"=63@?'.IF:
M';21$=1"@M]J,2UWWH_":48.EX(T](:7+3[6A- %0*],<+2C42F@2]7]=[_S
MVHMSAID4,)X%R)=Q%%/HH407]XD1I*'T8>0A$D82QSCR[&P(2PFF9U=L)[XJ
MCE2%U]7@G1.)&0V*&:L,"/3 A+.-L%7A]D&2B=F -U16,2,97BJ]F U '7G&
MK)IQJ6W6T7[]FUZX5?HO85+ ?88#W_.17EF%W%?4R")%C32%L1=%E/'8$[Y%
MW;-^A9N:B56K8%-HJ^>Q,CB*?,$1&)A.#2BTN:36L/E.[!+K%6A5/9'.\06'
MUJ:^VLL-\5BUUUYPJ"W+LPTS%MVEVWKN<\2R;L.@M5OR;: ^'*;JK]^*^F3Y
M5JAU3_W/\?ISNOC<5S7DJUJ+41@10:,4>AY%$$D9ZY.>$/J!]%*UCD%!:#XE
M.PHQM:E7UU=L_"=J'=I_.PHRUL48:X4L6-UUQ PFYA'&8> )^((A<'$A<AT+
MBYETA#$9:<8<XO6PFPDOQ+)SQG-M>[R9[4+M=V:P2]MRF*G^X_K3__OAT]</
MS2G?QVR1W=4/;/M*X5@2% 0!C,(T5 M%$4+BQ0ED3** >#R5@9%3NT%?4YMW
M5M*V1]Q@(Z\+IYW!V6 :Z0^]@6>+48&SX/S^ !R)VB\!TH["S:#I9.HS38Q'
MR&:Z[/"NX2V.)Q9/))OKA<7[HKPE<[&)2=(12K^01?M76R?P-LOOYJ+]^OFM
MDFB=36P6QS3Q?9]"C#R=,YPS2%6?4*)8B)23U(__?_+>MLEM7$D3_2N(F)A9
MGXA"#TB"(+'SJ6RW>QSK8_O:[IE[MS\H\%K%>U12C:BR7?/K+T!2;R6) B"0
MYL;=V#E=51:)S ?"@\Q$(M,K_2N>:%,C[R^JMG62UA6;PP?CX]VQ.V6P$O]0
M<N_BI.<I1[R)=#P ^273,_#NL'_+LNDYN-42ZN4*UD;/&[!1XF;;(K55;OL/
MP*IW W8E$".>G$1'/>ZA2CSQQCUOB0[KT5%,_!%"JGYO7E)_TB\EVM7IJ%\_
MOYFSNF[JH-JMYKU-N:N7\TK:HZ37S*P9H;[>*[7>*ZB1%1@A*J!(TP)B*2ED
M6G*8IZPH29G0C#OV_!M8TNF=>3=$T53:;^H=LB/.V:O27P/^#,2!SK9@__I>
M@7W-0:<Z:'7W*9<]W%?$P8^8QK0/O,OL-H8:?-*[/<862@!6T[T"3#5X_0P.
ME37_VC?7WL5<AIYVG[+JDYC^L>JP#[[L?XM5MWWP:>DO]#[<\"-6AA\<P\-2
M\L,/%^9Q;CIVOED^\&K1#'JJ"BG#JBQPCJ$B,H?8-A.FC!>P2$5IW,E2".Y5
M>M%MV*EYBANIP9[8WI5,KYD&-U\P/K@#[\!1</5VWOQ@BNJ8.0X]JM/E!\=+
MA\KSZ< L?G&OY--<?=+O%V:]&];\8GAQ5X>C;K*&=\NE* N4);F]^"@2B%.1
M0\8)A7G!$<64LJ3TBH%YCC\U^MJ(;\V;JE, K(P&H/[!'CTC7+YSX49= R(\
M,(?M@[N1'5CAP9[TW6T", B?!6(7]\Z!IPSC7D<( ^CHID+@:\(X[XLZ]#,^
M/:V-"7DYD[@I@I4SF2J6%V:Z$ILC5.:09L: 4SDBE"0X96X%@F((,S4V?*D+
ML*%CLW@=$_)#"I9=-9=N!#K6# W,IL-.CC>UQD U*L]>)="HI!L#NI<,'.6=
M?G0L535[VP6B/ANJ7\K?%](>!,P(8CG6E$.1VO*S*K<5-YB"BN8JI5E&<BU=
M./;L"%,CSHV0H)42&#&;(S8W+CP/9#_!18%GZ/-*7V2<B>BB]B?8I5;BM[OE
M]W\US[;$8GYH^*1ADO-O'(4>+BJT6?.7/QC>RJB+NKU?V$._VX7\.UO]0S6)
MW6V]^]VIH+V.KE9K5BV^K9BT-?+K6JWK4S$:RK)"ZU3 G-F3-T&,S46$@+)D
M@N \360N_-L@#2'J]([>]C3U;Z$TR&RZ65U3F*&!N6W_#*Q:@"8UPY;-V*G9
M=1K92]@ KYK"&JVNH%,6M-K^;9P64$/.2O3V48,(.WKKJ2$A/]6V:M#QPC87
M>W%HKRS2FSFK'NJO:KV>*]E5_TJ5S/(\R\R^4*00%T3!$C$,)2L)UTDB,^S5
MM>#RD%.S(ZW$AP7"6J%!)W58$38'Z-TX/2Z@ [/SU5AZDZL[/%%ITF'840G/
M'8:7U.7Q9&BYM+JIH]15GZQGG"M!;96C@MN.OS(M85DH#E,J1*D5TVF:S-;+
M-9N[4<[+ ;P(9CO,<(OBFQT#[ JCJDY.WWIH+V!THX]KP!F8+!K1&N/M]TN(
M!)0[.ZUVY!IG+P89N;#9:16/JYF=^5S@X>?:.+W6TFE21#[III]O$QE6G.8D
M%PQ*D>00)VD.>:XIS)!4I2Z)PJE?';-S(TW-@FCDLV'A1L*@D/QY5!T/+&-@
M-?1Z]X+)_]SQ$@1Q3QC/CC;N6>(EI8].#2\^X!^0_MU8#^OG+^JNLKE@B_5'
M\R68(9Z4.D<4LCQ5$'.E(2NDA@(EC!<,XT([I6J=&V!J)-#*"'9" BNE>S#Z
M)(B78]'70C/PFO=$Q2L0W:=Z4!SZY M'"T/WJ;,?A>[]7,#MCR]*V 9DSY_T
MVVJEQ+JQ%\P?5?6]J:>9E"A'(LM@*FR!#T',DB:E@#DIA*8)550GSO>I+PPV
MM46]DPSHY0K(1F8@&L-U^4-)CU3Z2S#W+_78X U_;MY(:B\RM+*"1M@;L!,W
M(G8>=PDB8CC2A8"KL/3+Z'<$IS<M_]([QLNM=]3F($'>]9DPW^F;>>R3OET9
MVKYKC+#&PD\H)@5&$HJBL'?D= JY419*R@3.4:%XX51!J7>4J3'KF^7<R+Q<
MM=T$]X1M @+[O[?Y->M[9N\W[3\4XF>=G@$W'^MJ7 >/IPP-J;=/U@M95'_L
M]$BC^F*]RK[TP_H_[$<OXFFULK';V1^O/\]TRFEA3_LY1JEADX+ LLPSB')!
ML$:DR+ 3F^R_=&KD\>>BLIEW_ZM:W,GE@ZV>^+20CO'4 [#Z%WXH! .O<T_M
MG1?M*75[_*C-Q]LUNOEMYU$=O&Z4A7A*@<VZ._EO =Y2>R1B5FY=JY69AJ[5
MS$SG9K<VSA T[I#9Q#.*().,0JZ+0B!%%-?N91#/##*U9=B*V5Q6[@3=]%;R
ML.W/ >K@#T6 :>"E.BA"'EY/!*1&\G8"$//S<2Y T>O;G'MV/)_F@O0'OLRE
MS_JQG_HI[F?_]\<_OLYT@=,TPPHF0I8VTSB'E KCOG!C7A!)-)9.U]FV;YP:
MKWV[5^#C[=>WM_\7^&.^Y&P.OJJY];O;E![/DG [X/HI+0B.H?FK0>%?C5#@
MU1\?/KV^_0"^_O[A]S??P-]OO_ROW[\Y=+-V7IU'^O?8'O:SG6]@?MK9'+MW
MC+(DCT3>K+_C?PC/#EX8N)[_<[GZQ_O%Y]52J*XSPQ=E5O5W98]=1:Z(3&S%
M90DQ1PJ6,N/0K-$,(4UYFA?^B;X71O7YCHZ3LVMEM1FACZVT_GF[EW!V"Q)$
MQF[@];V5]@9L\.LDWI:GWT@=-Q_6$:+HJ:V7QAT]2]41B%,)IZZ/!J9ML?I^
M5F8L%]CZ,DAPB(E(;%A!0IGF*4>9/<AU+-^U_]KID8>5RC,=R\+C1@F^*@\=
M)NS3U3_1:D^YN,E5]L7C)E3MJ7*41+7_;V$+ZEVU8 M1L?G[1;U>/6V#SZDN
M.=<BA7DA%<12",A1D4#;ZB@EB=F^W1HH7!AG:D;V5DRPDS,HI'\.5[?%&0&M
M@==K"%#>R_@"#%%7]KFQ1EWL%Q1^N?XO?3RDZF;U77U>50_*N)LK]JB>UI6H
MWR]$5R4<%U)2EA-8%CB#9@\N(%-I#J602A8)S]+2J6:"PUC3HX;O"C3B@GUY
M;^RU^O/%Z[P1=H@PQL-M<)+H@2RDAOT%['RJ-T;#<*P*C$%?/\_:B4Z@]-<_
M['_%B#4,G70YK$/H]DCHA9.'A^6B26Q]6WVW-=5E_5FMOMZSE7IK2S:LE)RE
M*"]$GDFH2D0A3AF'7"0E+"3*"IUE95DZ=0GQ&71J/-O*#&HK] V0&[&![.0%
MCVH%:JL!>%4MP%.]]Y>_^=Y><9@3BEC.;?6*-"]+B$M,(,4Y@RS#0B1FTQ-%
MZ>EM1IZ5<;S1M[]\)AP=V\CH#NWXME_WK^W7?2OQC2V3 1JAS5\[L6/>1'('
M*?+M)(>!1[ZQY [%\2TFCV>#^[2OGI3\4#%>S9N+VF^:I('UC%+&F> YS$F6
M0TR4[7&8E1#I/$%Y1HG&W+LC^^FQIL=&G:A@OI/5N]7Z&5S=:"8*5@-SRP:D
M/2%O0"=FU [I_4C$[H5^9K2QNY[W*WVBO_F%!T)+('Y7BR?USDAH+TS;JM>V
M+\>;)V- /:C5[S_%_&E3S<'\?_F-_9PIPPT(XP(65"*(F4"P1,;@3')"=2%4
M3K/"K_*AMPQ3LSK;Z]"K5A%/*@F9 C>2&1C8@>FGDQ[8U0,V\C>-B,!&@QNP
MU0%LE+"]IV-6)PR&,')10G\Y1JY%& S4<0G"\%>%LF"MS$/WMPOYU@P^7SXV
MP=!=(O-&CF]+8Y_IY>KAW7+5))S7S64*X^5;-I9_K)9U/4O34F!$"42I-&XX
MQRFD-&5F5D6I)"D*PIRJ%@XBW=28LTM&6G4Z-FG]<J=E=R_MU=,C6"\]O<*X
ML^I*N;]HK@8GX[WYV=-L_PK&S8ZEUTO0J=?<,6P5O&GO>(&-CC>@T3(F60\
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M?B?GS:D\O[^L]* 1?X DRMW$N%FV@\$]\*X0#>E!<BF/$!L]GW(GP>1R*H_
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M(&K[AGW[L?S?:K7<N_U:=%\U31$K2B:AH#9%+V49I#I7L!0Y$XA3;A:O<R$
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MQGFMZ/##F=7(GT$C/V@4""HA[#,Q;@0X$-P#<U]4I+V)+P"SJ)SG,_ZH=!<
MS$NF"WG%-?EEW]C/WW\^JD6M7JN%X=CUC)94%8A*F&3$%C_7&O(T2R&7MN.?
M1J62;/9=K?C2+\/L:"2?];0_WG#+ZO-J^;VJ[64-;19/U292K=E/Y6VLG8:V
M5*3(B10PH]0XY(FBD$F60T:+DBM<<"KD;*'N;'&Q;[X9?&'XTA;?HT'_SP79
MU?"]^CLYN'W;(&-$!)V,X%4G950CMA>' 1+YCL?Z!8E\9Q4^G<AW_N,!ITFO
M65W5G_1G\V791)D_+^>5>-[5O<9)7A0%QI#::AI8EM:;U@PJSA->J#01G+AQ
ML..(T^/B1F9[;>AQ3VJ/<P@'E!W.?N(B-S!CM)!]TF!?7/!7*W!@J78'&#W.
M;N+".=8%\OOECQJL[Q7@I[Z37:WV[L2_6IA=[:']AW9_,YY7]0 >S?\N9;2B
M[.Y ]I[/.+QFO,,8=YT.3EX\'@LSE&^%L'VVZR]*J.J[C;=^5.LW3ZN5&6XF
M2J%4H3FD169,NEQ(R O,82Z*G"%9:,F$G[7<-]ST:/K;BDD%5EM9ZQNP4)Y7
M.GL!=C/G8H$V,$-OQ 0[.6\ TX8BP.U\OOQA2$0UM/%FI62U!K;7S WH](AG
M]+F@%=7RZQUP5///1?67-J#3,V'<8IPAPQ^R?F<$?5_73_8+\$G;DTOCBCW8
MA*99B5-,-9=0)T)#G)4YI#K+8$)Y*1G/&4F]BL)>'G)J<46#MMEQ6ZF!G5)0
M=7+;O=<>[OKQC0/H;JP3%\J!N>?S 8+O]Q#<'92_[</2FV;<X8E*-@[#CDHY
M[C"\)!Z/)Z^L\MA>>7^S?'A<+NQ=]R:"7N8($20(S*2M7)$85Y0EI8!29Z4L
M"II@ZI4_TCO:U$BGJ\.P$S+HP*(?8#>6B0;;P 3CC5AX=<8^)(:IRGARQ%]3
MC;%/^;-5&'L?"O:+-ITPFHZM]N4K=:\6=?5=M7$S:[\VC;!F$G.L"5>PH,*>
M*I0(LI08+D$LT[P@S SAPR4^@T^-6O8[OK2=@P^D!UWD]Y55X&]=ISU/WO&:
M&V<7:Q#$AW>Y(H(=XFIYHQ;;]7(78&Q7S!N:$ZZ9_SL"8O;OS/>QR>_]6OTT
M_[\I3'@ZP=>F_GY:J"ZO/6>*%QB5$ F10<Q3!ADI4BA3X\))1DG"G8IU7"/$
MU.@/_T9(=G@+)$_ J^[/S2_AMT!")\KA+& $^ ?F0JM!=^? 5D6U_]?61.VY
M=-!<2K W%$:<#(\3A1$F9:1CAF$GQ^]XX4I4>\\<0M\]WD'$E=H?G$Y<^Z[
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M0C_;%MK;SXPX&1X;RPB3,M(N,^SD^.T[5Z+:NPF%OGN\'>E*[0^VIVO?=4T
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MD,ZPAJN>EHU(<\M9CI1U#EHF9('S4H&2I5A/&^8^;*IG;HTQED@1RBHG<=D
MP ZB*]O!NIX&8D!KQ_L! (O,\&L+S7JBY?2;I+,R')%?@"$H99_K:U!RON#P
M(0U?>GO  +]K^HCA;\5_/;7R_1.98UQ"@8""I *(IRG IKZ9*AE3N"*IJFB
M4/^R)>,C[%:2R80_PEAO5N1+<W^KN>(5..2T&*DK@L^PZ+]0&+HF^N-8--GZ
M$3D>M0<R?F1J8<O+QZCV@%E%JP[-^=%H5VNJVX@D4NF8%"N 4DX TNMQ'4VA
M$BBE8RF<XJ)25EG/)UL?6R"U+FVVI%.C_N6TXWL:/CO&\@8E=E)#AT>X7=5>
MCX,2QGX/@]+ 2><.'^[3;_*]Z/BQ7AJ9C.6[G[PYQFVR[+-*\9(S J2$A7Z
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M[ZJVMX'A%K$V?NRM6:T^X*T\,7^07_57HZGE]G'>!GK=;:BL+"3," (T30N
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M.24H#&K]V.:S5T8^RF32-L67DOF)6UFKK:L>-]H'^UJ@,H6*00D8$CE 0A6
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M 5@XM7[:;=[J755,D\52OI7M?S_,FFCJ[E$NJ%&?;@_1)S*#)&TN+V?*;,_
M C#.(<@T"Q!.58H@=\L4M^O8ZNL]:-YXN[QJ,SN<JXK90&T7;P2$;[ Z8XVA
MR:NUR;\8N: 6SHW979)2T))C#CB%KCUFT_701<@<X#A1C<SETSZBTBOYCRGM
MCFHDK7)6LA045:8 @CD#1$H&RBJ3!,DBPQ+;:T?OM#RVP**U+7E%]0KVH9[2
MY<I+!&$//(M31E](HF]@-6A<"X"+2+,G$$-I,5L"XJBZ?,+I?G'EW0\,J*%\
MPLY]J>13;_"+AKH=HW<_^7<] /)-)UW7?:/24BE,. *L(A2@5 =!6%84P*(J
M,$:Y(+E3\</>WL;&44<'!VM=/T_ITGZH)4,LQWIA6<*J!*B@ A"6%WHF8"C-
MD,J98F[G/L' ?J%SFJV,8@R\[8+.8!A&GD'6X*T-3=Y8?U>= TPK3(+&E?T]
M#AI.6CE_&$7:?<B[O!&74BS?:U--E;4[=5AW;;M5UES712;$Q'D)C (+0"SC
M@$%:Z74N$[)D14YSXESRR,F$\7'/VH/$#'AB"@PV5X ?Z.(/V1[S;86KG0LB
MN0V/'2_%A#PR5>UC;4PU4%O4? Q:3\D+O= UEMR,&+KNDA=$)VHQ^;7COF__
M;K:J5\]OY@\/\]G7U9S_T5QC7-X]K98K.A-ZM3XI5<;2'',@*DD (D( *C@V
M,J]2,5*(4ED=,MIU-[: MK4X:4U.&IMOVCNWRV3';/N]?0O$+V_SA\4Q,GE=
M"Z'3_K\],EY' 1;-#W8J8._J[@&!PZ=\=63XE"Z7M:IYL^.A6]8$=I"9>B(/
MHZW-C%!19401HYTO $(" UJ54 =>%!$H19I5N5M%D"NL&1L9'3J3F$M-.A X
MSMT^F=CE55#[NN&TB\P&&Z3(3!=Y?#QD<P+@&EA;YQJ+!A;@"0#>L4I/B$:O
M4I5X7\_HC-=&WWHC++A3!:KO=G[*RQ26/ ><$*;)&9> Y$4&5 FY1)R4HJB\
MY";\;1K?NOAJ'8HK!LCB.&=HT"-3[HZ.PL:?/:73'8_BB%I<,5Q>:A?##-OP
M,AAJ,WSUSO#MU%1,E!F^'\WPB8USX74SK@?84E#CBHY>0FGC>ES.2' $:-AO
MJ?)FOEPM3;'KGX]ZLI7+[42'><Y0G@.<(000*2!@I=(!C>(IE415 @JW_=YS
M78UO_MIFV<C.5D=QN[.HVBT&0B 5>=)I3&RKUW=&1A%@NX1$T,C\;&>#!MV7
M7#Z,IR^^WX\8=@4T=XKQLK2D15FF&CZJ ,JE HR5#)0XQ12G"(O*\9[AZ8[&
M1PI;85=W$=PS8):XP@(Q;'3&-<=2F /*J !EBF7%,TR+U*E4XO50#K&%\VV^
MTA'.-#R<=N1Z/4B1J75?0?C&',Y/G\RN9'<-<97\1E>73A6=F;8?EJ \>Z:K
M05FVW]U#CKWP;D^&M=QQ@#DJ*E:!K!#$)'<20!1F0,A<OUIDHDH= ['_6[<5
M=NQVC,>"[!W$@R\VH>S6F_?> '!G%(\%8RB&&=$2T@^.(P:*N1C<E("2^ALW
M6[U[VJL ]>W[_&FI(_UO?^J_/6]KE^E5/:HR7@ FI=31B^8D(GB3$81(5>&4
M(*N+;5Z]CRVH@;^FZ3\G__)/."_1OU9%FCS4TZDY_SBNXI>NJ_C)IW49-.]2
M?DX#I@3GM&(9$!DL "JR'#!2%(#@@F8"5;"J4H>]ZYA#-LR$<G(L!AD*BUWJ
MF/!&GG"::G^M[<F[IZ-:?VL'DM:#:\HL.H'N6&PQ%OA#EEP,/ CN=1=]0+Q8
M?=&IT6%K,/KX>U2)T:L1_QOK[W4<0:>ZUWHNWNO7EI.**IA!E(("*0P0YBD@
MI:( (4)SD?*2V%THZ^UE;%/XYEIV:VG2FIHTMKI?7#\&M9_S@T$5^[31!R6O
M^^MG4;CJ!OMQJX/?83_KV*E;[.??[*FKHY3DJYVLBI]?Z*JY6U#/GNK9?7?V
M,9\M)VFFJA13"7!1<E/?".E044?Y5&"(2U)E*'.2&K3O>FS4L+%\I]1\HFT]
MGUQ^+?9V6Q%Q$(W,(%LPNZ0O;79B[$Z^2/,4Z65N8_/-.GP)J*CCC%=851W[
M[H=5UG&&Y4A=Q[V%85-KW\X?:#V;H R72F1(+X%+"! M=6!3%!PPG'&N9$DK
M H?(K6W-&1O-79N\V7HU4'9M-Z)V1#G<.$4FS]A#-%B"[3ZRH\BP[4SZOR+%
M=A^^4#FV!ZWZ*B7]D*U*Y#?=P!O=W_U\4?^C,:3;B>%EH3*<YT!ADUQDSKQ9
M10D@N2(*$P(5*EUH^'*78Z/:K<5+3]ZT@-F.&\."%YG_G'#S$$&RA2*P -+%
M;@<6/[*%X5CXR/J3GOF*=/G=_-_(.?Z@4_,]^*)[7-1<TYKYP^U,[+^P\\Y)
MD<&R+$2IPS\B :H0U"O:G.I?65I4*6>*TLECL];^NJ*+E1W[7&63R[-U:%F\
MQ\P8V63W<?.#W)J;T%7"Y'T],T4_3>#1VN28'GG5(*8\SU.("E AHS]0&LD3
ME9:@RB4QNY1Y6;%N$-_-+$7V!A["M5TO-(!2O_XB0V<W(0TV&)'G*F/93=*,
MQ(Z!-\G6]F0S3(>O[7P@8#9M"&##IMQ>9=&P>;DAP#M*W@W2J-M4RDTMM<7S
MY/>O$\ZS J85!*E"FDIE:M2CF#0"Q5"23*$46A71W#8YMCC[]Z^.1\L[Z/2S
ME9_/D2GG]T\?OKU[FWS]=OOMW=?KB>/8QYZSE^[-[</?_;(]@]EI:I#']MCT
M];-WXB^^=V<V"@*?Z>)NH0,S_9 VJ5GK:N@3R'.()>:@H*H$"-,"X$Q40%8D
M%Y3ALL@<99,L>AU?IDVG?+$T5C?S'16B-HL".DT>:2U /=.1RF.]HM,;_<+Z
MCMLK_?+34IA()5D:SQPK%]B,D&5,$A;UV)''GM"(-EA_KY/6Y"[W4QO="I"$
MO*MC#5'@:SN7^QWX!H\U$,>7>>P_ZE4%54</"VE""JD_::*+M_*'G,X?FR6[
MY-]G\^G\_OE+??]]M>QVD3)8(,:+3!-7A0%"1M(<RE3_1"$M]<J9(>50!=7=
M@K'%%&O;&R+;L3[9FI^T]OL5Z_08HWX2&P3YR)2V-C_9H'\[&O2=2J7&'87!
M2J5VH['8?1;$SFBLMJ.Q:'P)=4O]&@0OE$CU:'C($JG^?A^42+VB(;](N=6[
M[ZZO;;4?C#@]IWI"YY4P!3,@H!*5H!"8,XEXEJ>%6VQ\LI\11L/=/;ZV.(;C
M7:;36-I%L5?C$YOD&_MN-A<=8UQ+ZL4@:&!ZNJ=!0]%>9P^#S_XW^SWY30!K
M>.5.M4?,FFU.'#QOOL>%K!#,F  I%1R@--?K94XX@"464O&L=+P2[=C_V$+-
MC?EFO_YT1H>C=(_OP-@13$2X(U-/$*2=R<@3KZ TY6K#H 3F"= AM?DV<[VX
M^F?ZW&0KO)\OFJR;3NEG=G]K\B6;"YT3)O,R3;$>'"PA0%)B<]VB A6GJ!"4
M9QQE_MKJ%A:,+T1J+/773+=!W8[1(B(9F='V%=-?K8TW)>Y_Z7($-PXD6P_B
MZ*4[0!=-+MW&AA=32W< J$\LW:49S](_]:Q>R8^:,\6'V4I_X6HVE6WH^)>%
MJ0/,=-"&TBP#%!890"AG@)DDC0SG1'*10RZ=0KA+'8XM9FN,2CA=+)[-DT4?
MS'F38_V'BR#;D5=(Z"*S56LJ:&Q-ML8FZR5A8V_ :C26R(0M2'.ITV%KTEA"
M<%26QO9SWK48I"ET,_TP$_+GO\GG"585+0N< X5R"A!6!)B-(R R105")"]2
MU_(+^SV,C4'>=>4"6BN3QLQ$V^E<8N$ R'[2" )/9)9P1L:G<L)I[Z\IEG#0
MXM#U$4X[=*(DPIDW>BL(BOE,4X1>,-#9'W=*2;/KK!=B'S^\OONR/CM1"I:2
M0Z J9!(D*@2(*CE@+&4Y1()53#AJX%WN=6P/?&MTLK$ZZ<QNKT6^:BQWU8AQ
M&P:[>"(XN)'I(A"N/F)Z]CB%UM:SZ'EHJ3U[,$XH[SE\V#WBZ,I(/:^+['W2
MWZ:)*&#%)98@X[FIP*(*@&D. <FXY)@K+E-B&W"<ZF!L]+.V<5L'TEAI'VV<
M!/%RL'$M-+%WA-U0<8HT^ESW"C1.-CA8G-'GSFZ8T?L^SZ/ER[<:/^I%R<=Z
M)C^LY,-RH@@L1(H(*$BA'VY!$&"%HD 5*<)YRKD0J4O X6K V!Y^RYO#KXP3
M>JXT?B2-(XYQB/- 61YI1X0_]FEW>.3=3\,]X0M[4.YJQ+!GZ)X0'1VO^[83
M1BG#[ [?SGG=G>^WBD*OI9HOC%S'[6JUJ-E34[7VV_PS;<7>E:0I8Q14I&+F
M,)X 3% %*BE2+ 3!:<FN4<MP-VELY'DDQT#%?SVM[R>OYIU<T'6"&!X#9T>=
MPPY'9#(]&HGFU.OV[LV';3I1Z]%-PAJ?C.[03;+KEAFQUK%X^AC^($?5R/ P
MZT5U,OQAO*25<47+_E?:33K"_N6^$RK/DU(R(I5>C9:$F7H1D@*"A?Z55Q+F
M62%+[+179MWSV&CW[.UF]\O,=LC;$6H4/"/SY@;*XWO*)Z7BP]Y&=D(K^,UC
MN]X'OV7L!,JI&\5N#?BQUM^D20^7XO:'7%"]DG\R&W%WZFT]?=*O'E?TYK+@
M!&85@ 7,31D+#EB)<I"7+.,4(29R2_%Q3PO&E^/46=K<<FQN-RX=KS>ZC@'.
M&:\(KT"1D1(@*2I 9:Y 2E&.LRQCS?QARO.\^ ALK8B'_]I\0%O[NT$P"5*)
MZ,;FW>>OPXV/W2P3$?7(<\W:\J0S/6EM-QFWK=G)CMTW2>=1N!G'$[F@\XZK
M#8/./IX '<Y!OLWXS41]FRF?Y.I.Z;!]PBI!RK2@0+ T!4@A#C"D)4A141 B
M*8'(*72VZ71L47.[Q\CW]A@[/>-74[/'>)/,9)/_OJ(_>Q)!_4?!CN!"8QN9
MU2YNW=XDGUI8M=WAR,P%I: ,9M7QH+3E L4A5SE]UE<0L]-$W@;?W^3/U6OM
MPA^3DBLJ<(I!ED-D"FKF@.5"_T,YI2*O!%26!>5MNAM?$/QA(ZCNRCB]L-HQ
M32BH(C/,CD[Z;LTV8VK2V!I4 O,R)('%+WLZ'%CV\K+KQX*7%I_QK\"[ZHI.
M&C7-VY_U<L*P()F".GJA1HR#FRW 3*^J4Z8#&%ZRO'0[DCG5R=CBEL."J,;.
MY._&4O=4N&-$[9CB6IPB,X0/1%XE8L]A$+Q [%%'@Y>'/>?JJ>*P9]_K(=+S
M23X]S!?TFXY+Z*-\6M5\J5FFR]/$*4DEK9 IN@@!*H@$&)ORBUQ@S'F.R[RR
M%N/IZVEL)-#9FNP:>V/B[%]]9%YZ,>YGA*#(1::% 4%ST, )!=Y 6C?G00RD
M:&.#1Z]R36\#PRG4V/BQIT1C]0'WG-[NY+:MG/4?DB[>S<1;NI(3DF8$T;("
M,D-&_CN'@)D(BE58%0Q*I5*KX*FOD['QYCKWH2O79BQ-WAGE+.OJ5;V0]G-E
M**!BGX'Z8.24[WL)!*^<W[.-#I;W>\FMW=S?B^_U%9C1*ZWO\ZG^Q-(<>*Z>
M3<W,4UL"!>4TIX4I5<UTZ,1@"BC!%2BEP"KG*<L4=]MIL>Y[?-LNNZ;_/TT&
MQ<KR>J$[\'8KK"A@1B:.?11;JYLZN_'W:9SA"JP98]O[P&HQCJ <Z\2X-G#U
MK86_T'K6;3:;I(WWT_F??Y7B7K:Y95UT7;(,4ZB#%H%)IA=[E!NA]AS@5+%"
M,IYB+!RE\MPL&!^#&5/_Y9^R,OU7I0U.OAN+724_?8?#CM$B0AR9UW9O)AC3
M=P^RNHH6QH6D\>&FRYF-<(_2$\%8EQ.L;'BINPDN /5<37!JQF-WZYN<R3FK
MY]N= \EHB9&.Q@@1FMM42@%!H@!95B)%]:HL1[GUEM91\V-;CZT-[-] L,'-
M8IOJ*C0B<\P>$#[;4<>(..Q!787,0!M/=E\5M[VFLW[W;C =?VJX7:6S%N]M
M)9U_5W"5J]N'^6+5U;1[]_-1SI;2+&??Z_=..)=4%&4*<EZ4 "&1 \JR I09
M1;1B*J\R'$C[JL>,T7&>2>9,Y')5/S0A!=TQW>3%J%;[:=IH/]5;[:=6'[G)
MQ]3?R3*8A%;?"-J%=O'')3+[]LIMW23&\*88V:XW-^W.F/%D$"$N"R2'DN?J
M,V4LHET6<#E(>=FT=K4D]#K"7&YDACDM&!<H Q7+-8$67 (J< Y2*2F'@LFR
M0I[ZST>=C8TF]R6(UXNL90B)YV.@;3?EPL 7?1_.&[EK))O/0A)+G_FXPY<2
M8S[K>H_R\OG/>,HL=UJGW^9=28MVQ^XWN?H^%SN%HB>JHE7>Q&*8"F"*&@):
MI)I>B&89F:4BK<1D)N]-</+-GEML^[=Z4$C[H!Q9$>^A^:P;^DZ7<FD>FO8$
M('EH;-<QV,9X1PUFVR%A104IX4I_V;F1O*80,($A4%E5D1R6BG#HPO-!QV)
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MNP$+S@;':+\0;?CFSTW%NU\:O;;YXW__C_4K^A]&E_)__X__#U!+ P04
M"  0H6)375'\,26L  #;JP< %0   &%M9VXM,C R,3 Y,S!?<')E+GAM;.R]
M67=;QY(F^MZ_PO?TZXWCG(=:5=5+@W5:JV1++<GMZON"E4,DB3H@H ) V3J_
MOB,!<"8H##NQ-UVW3Y=%4A0RAB\C(R(C(_[Y?_QQ,?GA*\X7X]GT7_["_\K^
M\@-.TRR/IV?_\I=?/[\!]Y?_\:__[;_]\_\#\.\O/[[[X?4L75[@=/G#JSF&
M)>8??A\OSW_X+>/B[S^4^>SBA]]F\[^/OP: ?UW]HU>S+]_FX[/SY0^""7[_
M;^?_A%I('8H!@2*!4BE!M(I#3"R:K$0)KOR_9_^DDS-1V@1)VP(J60XA)0'*
MN&RP!/HKOOK0R7CZ]W^J_XEA@3\0<]/%ZMM_^<OY<OGEGW[\\????__K'W$^
M^>ML?O:C8$S^>/7;?]G\^A\/?O]WN?IM[KW_<?6WU[^Z&#_VB_2Q_,=___G=
MIW2.%P'&T\4R3%-=8#'^I\7JA^]F*2Q7,O\N73]L_8WZ'5S]&M0? 1<@^5__
M6.2__.M_^^&'M3CFLPE^Q/)#_?/7CV_O+!DNSG#ZUS2[^+'^[8^O9H2%#^&L
MTKKZM\MO7_!?_K(87WR97/_L?([E7_Y"_W(*5:G,2U97_.\W__C'F\6_S'%!
M>%DQ^XY^L/F,NMH!A. ?2YQF7'-WM<1DEN[\TJ3*=C:_^I>3$'&R^NDHXWBT
M^N07<;&<A[0<">Z\M\$ &L*42D%!9":!93X)Y-;+(N_R76E>$-$K52PP_?5L
M]O5'^N ?JRSJ%RNAK 3R8+FU8 ZC^Z?I<KP<X^)SB!,<,1ZUC4Y#1"U!R<S
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ME3(;G;'9$)$]B!S,:=<^ENM:90,X$U=IV%M"O,4)ERA8BF3H2_4+4] 0G<G
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M:9BFQP5I&#DM.3M YPTHFQSX; ,8YSTWNMZ!M F>]J=U(#/83I2V[TIIPPB
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M-:".=#9;FT)H\XAA.TU'S_.XD>_#13Z32%].:E:DJ(B>&?)&5&*@R"<!CR:
M5#XS+7,2H8WKNAM]_=X*=828!Q,^NE=-AZF TQNL#\T-UX=3&[#'66IOR B4
MCF!C")&\=ILJ#+REL)V<-V%$UB'8-N]>NC=DJR?RO]3Z97Q?-L\]9].U9+_=
M[!(;T$IA,UCI/;FE)9%;6N<S%_)6"[-.Z^^":+>E!FN+]E'ZG08$W4JW_V86
M+\-BO'A?/MQ2S7V&#*H@,5#,+2U%,<IJB,J2P#)+=6BQ,/=+<;; Y?MK]7O1
MW (O'<MW$/GKFU$ECW!3L 0ZRB,8$5EMF9OJ&'CBII#0%"],B#89ZZ>HZO<N
MN6-<=:Z&08#JUWK?_=-B.;Z@8'@Q4CDH55TW:TG52J &EU,&C8(VB"\IFC:G
M\ETZ^LW?-@+.$:(>!%2V/G6YOPF811EDT!""UR2DK"#&4F@G% HXG$!6VMBB
M72GL-VO:"%Y-U#,(X/V"O]^2V7PVI2_3>E#7FK?[',;",A.TM702DK96DK2U
M"@(:;6G3*5ELJ^O;_2CM-P':"(A-U37(P7B[1=JO<1G&DX:Y@ZL%3I4Z>)2A
M]IF#F%4LM8=F4=5^L> )+A3SN:BB1PKT7&PS5*%="O27RXN(\^OP=GKV"<_6
MC_8D"X+GJ""IVBS9\0!>^5J-J%)"P;EN--9S*TF#32[L@XL'-JL3!0R@NIWD
M<WEQ.:FE?;N,NMK^?#FEH&7)ED(77HTR(20D[<@]C=H*SP/'-C>*77$PV*3&
M,3CM1;T#3=D_,D-H$8C_Z[E#B_'J9X<<N#M_]O%G[6%L='3,/K+XBX=KW[B%
M+@CT,4(=4P;*,@$.T8%%DUB1N;8U;&(4]J/S6"/ZR&JOQXLTF2TNYWCCMVK#
M>1+%0A%.@<I*0,S: R9.6XOQ$G2;9,EN]/5[4#=$UGVCV$!=@PPS=K44GVN?
MG*9F;[/"Z8S?8RSU8P*Y-]E96X AKVT(G8889 ;GE(DJH<VR3?1QB GL WU'
MA+G[+G$Z_+4,=?<$H,Y<R7J]*6RUE$PF<$'6*28B9N:<+;%-@Y/3GL&?TCGF
MR]KF[FK=V_IX^>W6=ROC,/+!19^* >,*F7?.,T07(H@8*81#:WPCN>Q+Z;,Z
ME_=!VX/JH98J'$"L_0A7+_X8+T8L2V9KUW#A I*C810X(P($K2V6P+S -NGG
M+03U"[BV*-CB"AZCDH$B:]W<"U_/+L)X.A(,DU_M2Q48J*0T!&\SL,QE$B$&
M+]N> EM)&X9Y.PH .X#J<&WT"*]5:<R;\5?\,!]?X.=SG(<O>+D<I\7;:?H9
M:PITA)$"+N\,(&;R;T/.X+G.)*A@@\D\NEB^Y\?ML,[P4'*$1F=MQ#M,0T3>
M-;Y=XL5BQ$.T@;P#(!-=&PQG!2$Z!])8VE,^UN?$I[)!UU3U/,VAY\/N,.4,
M &A[C0(0MF3I:D^.*#PHH0VX:.L(;\5T5J)>(;<I,'DVDQRZP\8Q,QOV4=0@
M2DT^DI:(A/I"ZS5^Q<EL=5MR$QT13:N&")_/P_3S^7QV>7;^2$#UVWR\7.+T
M?2DCP9W/2B-X(S,HB06\<QYD"MQ+KX2Q;:#:-2?]VM5F<.Y5X0.PNX\P\Q'3
M[&PZ_@?FMYED,2[C>E*M)^=>R83$=6O,&OW=Y46]D5RS<&LB8.W(P&1,) (Z
MTT0NH)A*Y'HS!TRSD*WDGC?JJ]:>MWX+G)MMBH&!XD^V35ZMYV;>^HN5A1E)
MGY-4]2J!!5-KQSEX7:_ #&>*)94*#G^?;&&NWX+N9[%1NH#%GVRGW+(=F\'M
M*B@;LQ<@<VV-)BR%Y=8;* I9RBX%I]J4PS5EJ]]Z]&>Q.XZ#PB"O\S^2OSF]
M/.RB_OK?'G\%^C@9'=UM;CZ\]I1[-9NNKI1^&R_/7UTNEK,+G%]?,Y62T2;-
M #UM/Z6CA,@-@X@V<VFXY;Y-*FE' H^/*Y]<YJ9(Q14=8\P2<G:!K+V5]5U&
M HU9U?>*V&K*]*X4]IO6:(&GAR%A UT-V@(=7C!T[Q.ZLT8-"WYVQ1!*5L\[
M.E98H ,F8*W\-A8$(2EJ@1@;]50ZD4UZ/5Z$L[-Y[0-+.GI?-LNN)'\#<FD"
M%T)RX$0M*"\T>,E7\X-H(YF8>&K3%VTG\IZ'-=H'2?>M4?=:&K0I.J)Z[/Y'
M=&>,6E9_[8JA(&(I+$1@J LH6P*AR6A"4^+%>>:U;;,/3V2-MK_ R8HI;7GU
M["4=LSK1,>MC !Y9$<GGB*%-7F2@3Z!:(&;W]U#[:&, Z8B;"]F?*-Q<?OMM
MG/'MM,SF%YMX]%J6/]%^GD_#Y$J.BY??/LQG^3*MQI!^POG7<=KX)2.GK5+2
M9<A!DKE%H<!%3IY?-EED[E7)K6L-.V2GWZN=4\"Y?Q3TN!46\^5HP\/[^8:#
M54V4+<5:1LZ(=JK6'JSB(Z*?? CR5Y) MAN*:8%;"*;O[J-W&P5#*4SL#12S
M#C4T#(3=%LBFE$HR8VK'"?)(G:GC 1"\-PZ<3UP4%:PJ.WDN^\#L(1G]8*T;
MS3Z$R9%B'L#!O&%D4Q8G6%9%DU<AA*T=))D%Q[B@312LLSIFUJA,X@X9O6/D
M6+4^; ESH(S[+E+]:1KG.-D0'H-*Q0>$0/RN1SH0R0&$35)(S-F[>Y<^6TI2
M;W]JOV?/$9J9=2&FOO5+_$_&84-X1I-=B1&0&R)<.@&1APS"%UO(/!:SHWYO
M?VJ_3FU'^CU83'WK]_T2_S&Y(CPZ(T5"#RS5R2^^:'#H$@0910Y:*GE_XO$6
M_=[^U'Y+;SK2[\%BZEN__WZ&7Z_H9MDD(8CNY"."BE*#-W1"U2?5Z&6Q0N^F
MWEL?VF^]2$?:/51(?2OW%[R<A,7RQNXXM)K\#I&C!Z59AJ""IF^]E3[9D*S:
M2;]W/[??HH>.5'R$J/K6\HMYF.+BRX9R96R],RV@M:9X!#G%(YZ^%:1"%$;K
M*/A.2K[SL?WVM^M(QX<+JF\5UYFZR_. 7V?TH\N+$#<\2#2:<2D@E=KB+U)8
MY 2%&,88[YUB:+/?2=E;%MA)[7;@:N]">'T#X-^^?:D>Y.+*/$4?BQ'D5P15
M;PF+!\=YA$2DJ1BXL7ZWEN)W/W<G=;N!J_L(4?6MY56=Z%4&X<I,*6(@DX,1
M=$6IHHB!4,K!J!13ED(Q%W=2]2,?OI.^_<#U?:S0AI-"N\D9K7C:\$)"$9E"
M?\BR<!*,X1"#RL!][>_+M7>Q347=4U3U$Y0W3[ =KX&>D_?7H]#^AK.S>?AR
M/DYALLI3BT >C35TVF6FUOO+:UVKZ1SS:&1]"=U9\GXK&4-YU#N$BZ)N=-4W
MX-;E!+=9V&Q'ABESY I"YO5B)!3P0D0H7KCL?!8N[&2W=@/<-C+ZNPGH2+VS
MKF7=(V!6G53GWT:_?AIA-L5I5NJ4A #*.5';IFK(F(RT*;&0GIH<O\#TU[/9
MUQ\WG[@&R.:;%3Y6R+A9KT<8=*.TV5$2'("/\\ML^NNU>Y:T+=IHVL'DF"O%
M L22ZB2[4(2*4:$535R:6T3TY\%TBXACY3L :.Q[&+^[?M3D4C">P@3(=2ZB
M2@;!6<[!&R:Y2IA"><J*' ZD@TGN][9C. [0:74_ )!_ISKNIS\VX]OKHSCZ
M__5]W(@')&)9!F=TJ+F+!-$5"SE9D8E[[GF;1Y('$-OO-?R)8+3? Z.C=3K(
M O^W4_H2E^&/PQX:W?[GQQ?V;R6FHZ+^]>>3WF[Z4%_7L0HFA>4B0S*6@Y)T
MP#KC$4*2WDLET8O09'<^0=2Q5NJ1C[XU:-'DR+,QD$HF]T22LQGKS1@CES.)
MF*Q.;=Y1/455OW:G*WS<MRR=Z6&@(Q]N[=LC'@H]\BF=FI26SX6>0H[)3A95
M'[UJ6^OB U(<8"3(B,(S15&";?-0IJ%E^:D43,OQ5[Q>XV-88CTVQ]-+.B-O
M!@*/'-?<,IY!&NF(?<$@"N9 .Z%-"M(7WX;]W6D<KM79!SL/G/$V.AJ ]_WK
M='[=L(+8>HE3+.-E;><YQT#.V4=<7$[J\ZB5+[=NX/(!Y^-9_>T/LTW;QU'V
M-J!&"4;D#$I+"R&R! D#6F.#B;Z-0]X-_?UFWUNAM@?=]GU1_&*R"F?66_4K
M+I8UH?0++O\6QM-WL\5B9*+0SGO:F6@2_<?%VFN(0T'#7!$B<;9;J=?W5NHW
MG]$UI+H7;M](J8/#R(W++W)>X3Q,KF4V\E)FBG<1- D#E*UM+WSPH+DIJ*1U
M+J9=R[6W+=)O_6<3?'0ETKZAL:J+FJ_GSA'M[Z</&:LL98Q22">AY%K-S#/)
MR0H$&2292Y4T.K,32G9;K]]JTB: :2#H06:&?@KS*1VS"_(2%^<D[D-"N@>?
M<7Q ]S19'85S5XN08_&I+G+3P,A2X)\E0O&%@8HNDU:S 8K:(S=2.XEM^D!M
MH^CH0.[>Y][D):SQPIG:%3H62P"VGF*"$*$VB!8<?2BLS;B4K23UG)3N A,/
M8K1.Q#_0M-#]K7IX/ZLMG]2]-6G8WVHK?H1*,:",((HB+S1;!JXX SFP*"-Y
MI2ZVF=[9RJ;<NI>\M\++L!BGVM-[/+E<UOCN3K>D.E9!<FO!>0K<5.8<@G8.
M@A(2558NJS;WOP<2/%![M ^>GNC(T4QUS\1:'9')WO91W=NKECGMK0!CF7S8
M>BHQ75U;+12%13)!P) "UYK)U*:&N6N#M?+G[P%[L\8#IBUM(<4- K?:U0&C
MM0A=4OB QF-4D46WV^.<W=8;J&W91_5WHJ8&4A[$9))?<+F.,FLNZ9H-*;0,
MK#A@Q:P&K#CP+&LH.N88; IX_R575R5QCY'3#Y::J?U^J=S1&A@>D$9D,0RO
M#Y%K-QHZ3^L[",P,M FR%K0H+MJ8V#MD]&N$.E#L4U#92\8#N/3Z#<=GY[2'
M7A#JPAE>M0)<;:3%^\OE8AFFJ_*D:S_0R<P#T^!=(4E)C>!HDX%*J!T&S3&W
MR57L2VD_%UFGLD]-]?:,<+D2]8@)RX/0''))A5CR$6C?"L 2N&.)ZY)3KZ!<
MD=FOX6N+F /AN;_ZAHK-S5Y_*,[\'Y?KZ\$1]RQE:41M&)&JF\L@9&+8,<Y,
M4D5RW:8RX$""^RT%Z!^O':MT$ [A%JEN8W44$[JL78+(=0W-'".A2@O&1H:$
MMJS328_[;83V6V/0/U8[4N'AUG6V#)-N7OH\EB(<:58P.\^AL-4HY>3!2=IH
M!@W/N7A,C5ZX/TI./V@[E6]YO 8&<$C?9V(CKY&G_V>CLB %#Z BS[0;; *I
M0U0L"!=,/ F0-@3U4_S2%Y0.T<(@ZQA>S28$NME5J>\!Z?Q[GW!\%O\IDCI*
MWK^?GX7I^!^K%5[1(K/).*^Q.LT?;E']OKP93\,TC</D^HG[3;(E9Y6"9@&R
MJ$]/LZB97IM!*XM,*Q2%MXG6.B'_6,-T2TU?\<5\'J9GJP4>>\41:D\;0S87
MD\DDJ=JCQO $PB1>A',QEC:/H/<@LM^H]O2(O&_B6NGS&9B](RXS'_^@KHU@
MRXO,;I"G0PD):P6?H1-6&73D585ZQ9V28%QQ:]KD! 9A"V\* [;MHOJ2_)?9
M-&WYZ\_TU8((J<I>/S3/02,GJ4)*@9&W$@*0.U% "Q%X1LP4DC<N]^B*ES^#
M9=T'W]O+1GI!QP""F,_T>^_++8Y6O8%D0NZ4X>"#4*#J$#COA0,Z3IA23$JM
M>1.(/TK.4.:Z](.16=<*&P#J'@HO/"ZO32L9+J+($0UX[2+M\2SIJZ0@6*=%
MYK&0()O@<4]"^T5J!]"8G4Y/?3\\>8GCO^$4KQI_QBP*T]5;#C5=D!C)RR1
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MZ3\R!@JP122L!*5,XH*STU[C'\)%OUUZ!G;P]@:/ 6R-Q]W?6UQ>]3G^//N
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M._URN5RL),:O)K8(7Q)C!M#P2$*+K+ZH1]J_11-W2?M&;W2?(&H@:.L>"MM
M=Z1>!@"Q_<K\36)%*/)5"F,>E#(((:8"7N00*(22$MNT=WE&CWY:'[[M-#8
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MDR#[G4P ALEKZXSFH<V\OPY?%)V@C.6$IV(#Q0T)CCL]4U""%9>4AT1<K%]
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M:ZD6?]2VN<W* B^,98DB?Q-K97M1M0<^!N*Q:"NS*N3#-X+G /*Z!N3Q('D
MRK$UU@4,!Y_J7ZX;1Z-!$;RJ2],"'6U-\ GD*('3J$UPJI1&KO@AU/8S3[V?
MV_TP5?8/U[=_I?/+/)M_N<Y>)"<=!N/!V5SW^]D(H9 W[ZSAN<ZX<\VZ&_:C
MM&M;.@)V]@/K<8KL *@WY_[QL8N;,R\4CZ[H"-G64>&:!$KQ)@/.B@_29<M9
MFV+UX33VD0P_9?P^JM8ZP.,3_#SPW+6,P1>O@">T-6U<Z%P7\F,R3RG2D:<;
MJ@D@]R"REYA]7)P,GMAZG-+ZQN-.QUV26^T"25 'R>M<V@#>: $RA&P<74+$
MQJDQV5^,W@PPPX%YM/8Z .<FJL/\&=/7^>)\\>7'Q]F7K\3<58SG8L9L52"X
M8*F[[AEX1DZ[Q2!-%JD8U<:I?(:P;L%W/"@6[3341:O9+[.$\U6=A_AEB5>+
MH3>L:$WDAT#NKJ[5ECES<,CJ\&.;K"O,D,R:@.U1DJ;U!D\)LW&TTH%%NUJT
M08Q\Q/-PL4-R5UQ)7Q"]EB EX4%Q82!F3A%=5#:%>J!*&\]O&'W35EB<$G@-
M]#5UV?UV#MSN[.DC=KS(G+(@=]FH>LP<B2_&:(%'S";1.7/V7O[[L25F!WQ]
MVF;;4\#M-(KIP/X](<R;?);1I03/-'G$UM069G(:ZF0$%9G7$8-2C:8&#*&N
MES3V5 'O86KJ&WK_6*X++B6S04DRW;&NCT;K(89<'TJ--J;0+S::B_(<9=V&
M$P=B83C8]E=,WT![E=+EM\NU)W%[+/M9%B)(RQ5X*^J8:U9'-!I+_H,N4C%6
M K8)9/>GM=N@HSD8QU#>_O#T5_"<K[<O4YA] I36Z1^V.&V]\,"EIC-'QP^\
M5Q:$599IS,7QDQO#H7-7IH@\FJ-O7Z6,-I+EP##CJ6+F*[.N#1=8TYTYI$3B
M(3B0P^) Z)AB-H:%^U-&'XDIGOU4'QT![9[-&@A\ZBCU*6X>,\1:%)]\;4].
M48)*%(5[Y4,M*BK)%NL5&Q:D'O#Q:6/4#B VAE*.O1U'*FUY8'@?5D%8;T-P
MEJ)Z74LN'$7<H;+&L^=(7JF3I=5@N^>IFW;Q]NFJ!$;7U(L<8[;I#*KS&B[#
M>8ONJ'M?:-\(]11+D_0\R1AM+")#--R33X>U_ DU9.X<<IY2L6W[\T_2\W1W
M4]C][YT)5;)"12&.YW5MB)00ZJ&UFIQ<;A13JLUXAJ?I>DD]3?O@Z+ZU&U$[
MG2=);C'Z]J\_<+XB4UE3ZZ3)FO=<I7#^_V-8GLF$,OG(P;-,KH6H<TRSBI"3
M0K)MKFY-/GG69"#Q+ZF2[QC4GEK/+P[:O]&%]OE///^.OR[F%U]79UF;XF*.
M$%C-=EKOP M15ROS;+6SSHDVK:3'T?V28NS3 ?HH[;XX+-?3^OG/Q9EV)NNH
M$YA@2;[,&W#"T?E-4NA<LA&YS7S$@\A]2:'[Z9![B"Y?)F )@4AQ**+AQ&;A
MHDZ2RK4 ,WNP3$BC)4-A3UYK_13!+RG&/S%H]];GBX3MN\7E\LQ'Y:+."K 4
M\OQME:PJ"-*$R(574;$VL_ /HW<0:,V_(FCWUN;+Q"S]V3,K4Q$H&3C&?'T5
MJXM'N8*DK/#(0E"B%TM;Z1V$6?LOB=E]M=GE<%CB.\S3;/XE+)?$]55Q\2%9
MU-T_Z/ADZ0 "1\J)_H3Q8M<4?HU2*B6!:V7JPKT"WAH"F6/%L)*T+VT"TMWT
M'-]4<ONGWAIS'%C(@B4(6B90'&LEN26BE"<7.,B8&]7W/T+0M'G-$;#PL%?D
M>,%WNM!QYQD]?./"4S^ND4%IN%OA42BYPAG=3K;4V;T48X(CQQRT]):I&+@5
M]@69E9O*W/KS?Y[33[V\DNPUT$W(.D43*I^\YGX*1,8HGM8B%I^#9LB:</P\
M;9T:F^$(>;R#?!1U=-&;=F=B/Y*.+CZ&"_P)E[/OI*KO>']POV:1A.82>!%J
MWIQK"-8X8%8Y3?SEXMN<L#T)G?8MI"GXQE?4U(59-[S]LIA_^8S+;_<.V-N_
MTM=ZK>1[3%IGI$K2@K5UD$Z,$5PIB>0;#.=1&LWC<Q?C411,^T(Q(LQ.IX>7
M$[%]6,[HU_X(YQ2L7M*_AWE^0[__@_[8?X3S2URLQ41D?7N]6"X7?]*O'S-0
M>'0:&KEUHXFEK2\H32E8N(.T?A5CGD( YR-8E9UBADO6:#I4NQ#SYB1>M6.%
M3%PX1J$2FG5R+X-708"7F$NB0T=A5#,6[Q'3I;>W#P9VA9;'"+R#;.KV'%96
M/M-_LYX-PIP+(FER#(Q5-;LFP:.*P&71B27G<FF3W]]%S?2H.4K%]T<*'"OO
M#C&SZ4#.)BC.4P&=5 ;E3 1R)BPD@\IY1(&\3<)N-SW3XN9X/3\#G .$W@%T
M?EM<X.I#^+'V#1>OP_SW;4>YDIQ%X1!RB+;N?4;PS =@,EAFZ'>#;',7/TI2
M7P Z1-^+%L+O $5WC?+Z:#F'F67I(#I%L:R4!ES6AB14&!,B>F';U/X\I&7Z
MO,*8%]:1LNX.+;=&9GAK52R*J*=(%%21A'K4&;1*M7E6D=#:I8)W4=23J[._
MII\$SH%BGSKM5 LD/BQF\XOZZOR_<;GX@,M4V:FF]*=+) 6SK0T-Q1N3#-A2
M!][;JSD\HC9E9R\]#V1$!R6:AG^S)[P<JN!%>VE/#:+/?R[67+V?(_UCY>T>
M7_2KE=O-WS8<6FVUJ%MO$R\<E"X,?"%;DKGG@FG$(H?U*1_T^9XNL3&@U5X'
M4Z/LW?DBK$>&A0O<<6 T+R))ER%D+4ARR,$+<O9R]-(FST)Q9IAY>O([TV>[
M1S9)XTEU:H!LC\ &XCNX":($QJ4$ZY#50JY"1C468"K*NOA1FX%7V+.?FK;X
MO9UY&4>VDR.EUC)?7<1T(^\PEK?X*B9H%60&)C+QQ4W==2(".,E1A,A1:S8,
M,\,_.FT5>@/T-)+WU#BZ]N?HUMWMSO%KKE"7PA%45@I4,A+HM'C@7@9/\F/9
MEOV<Y^<^.6U1>$/?>5193XT@8F;-U-LZ?/))KXW^Y(:_J%%+Q1286A%\)<(H
M Q2EF$&1O+=J$)8.^/BT9=OCHZJU_*?&UXWE77/X";_C?+?]W9Z>K)PI=;1E
MCE@GAV =NT;<92ML8MI)G<.>]]W 3P_"EGLYV&HK^ZF1M3TY=Z/-MY<;YS#?
M/COT_^W90<L-KRT-MJZ/,Y9#2&:=<-,A!HN"#_/ #_K\((3YEX.P]CJ8&F7;
MN&-]>'9<^[OXR[5#,08*/8P@)E-2X NW@$4KZYAC,0V['P_X^+",)7LY$&NM
M@&X -ONK'J%;1EELN$F,">L-W?2*>%#96HA.1V!>,7($F [W&^N>@]-CGQH&
MGA>4[QY7N)-#Y?H^)WYV)UEO<8:1)Z.E >D"Q;%,<O Z6>":+GA9HE5BV-3$
MO3X[#$(O*:_=3.A3PVEM3*]R(LN+'_4JOV+KTY^SU>K=,LS3Z\4\;VSLYZ^+
MRUIE^OE/^A,_UD+99FCI,B\B>BCK#*UB"9Q,#JSS*G-ABW9^$,[&H6<8 %]0
M@GP"-4V-S%O)WB=#XMO\N10*<W33EVQ8W4AE(6!,4%=.HV4B<S_L^>6 CP_#
MW,O,MC=1P.0 &V34U?:14J(0@CBS6"A*T5: C\)!$$JX+*.C:&;$FU3M ZH7
MF80?6^A3PVD;!O\VVYD:OCDOE>5M?47R0H;$0-<5 TK127$Q!+"I6!^(RR#V
M2T3L\?%AT'I!N?G6"I@:8#='9T!YQ2T>$9T-ABD(2=;% JF YRI#5DPEY(9I
MJ?>T7'L1, QH+RA=?PI%3 ZV/Q?W$WF[G$LRXAOF?/(1G0N +-62Z<BNRAES
MHBO?^224')Z@V.?+P^#UDC+V+47? ZXVM__M$HZ;\W+#%D4C4EM9(^BZ=U$B
M'1?!)9EJZ;/B(? @]G+FG__F,"R]H-Q\(W%/C:*UQ=U1POIA<3G/G^@C]%]]
MN>5/FBV/W@N#.D)-T5!X@@:"#0H$4F@2?5$V#8/4@00,J_=\08GY4RAB:K#=
MJSI[]*9?/TYL=\9R43"S +Y8!RJI I'[ CH$5W3**IO];-<>'Q\&LA>8P&^E
M@,D!=NU//BQLM-O7K" M&6($RSE%PJQ.MI%. =,E<+KG6;B_-O59)_[1CPT#
MT(M,WX\CX*D!LXUT-R]:FP-!S+@U8]O85B7'2E3@<_+U52M!-($N="\%UX6.
M !OFD0_ZW##0O*"4^_A"GAHVZ^+%I^]GOS6?)G/'ZB8E;BFDD.0'.N<=&)E]
M78F),@VKOQK^S6$ >D'Y\T;BGAI%V]OXT2)JN2VBCAD=CRR"(3F!TH&</!D<
MI")\\#QE']->3M"SGQR&H9>4+F\B[%X@M+Z7=Y91RVTQ8B"GS2:MH.Z!II-A
MR=(JA^3,698H4!7*[-DL\^PWAX'H!27&&XF[%Q3=XH@X$;=NYZUK%XL,7%F0
M=56EXL:!U\6!]2R+A$I0R+D7AI[[XC $O:2,=PM13XT?<NQNCL7C==%R&R&8
MDISG3$!M2 4E @67/#K0J'(4)K@<AG7/[/GA86AZ00GNEH+O!52//$(25VZ;
MM=<A9>X%<,4"F=IH(0;R_G))OHZ-M$X,*Q >_,EA0'I!V>TVPNX%0M7GV\W5
M==B0<D2K$*3EQ%60 J)&!SP@<^L%S/'989?[?7)8X_D+2F"W$?;4$+KS0KW3
MN*IMW) 95R8[#1FKY%269%R#AB B8]9XH_Q !WOP-X>!Z"4EJ-N(>VH473_N
M/'Y'7_/%I"G*U?DPWM$=S2EF\)Q"B.BCMT*8J,RP N ]/CH,1R\H3]U*X%,#
M:1L^K#L0[\00BM].IC(,@27D8!!SC1XRQ&03),<H '5%(-^O?/>9#PX#T O*
M6;<0]-3@N6ZYKU[>[C-QW;E*X65F,@-?-]YK%>B*E@ET=+DN?A!N8/GW\&\.
M@]!+RUJ/+^[)4;0UK8_>T%NNR*B&J"C&=!AKE9[0$(4T0,%F9D)E7O+ (1E#
M/SD,0R\H:]U&V-U Z.Z+X"VNM@U@ A7]7SGP4G-R\C0#'Z2JQ0>6T]6,0@RT
M0T,_.0Q"+RAGW4;8W4#HF=27DM<#&+T)(3J@R)/DASR#CR&#4((N;!N#QV%=
M)_M^>1B@7E *NZGH)\?5]4C/W6F,3=G+]A5QVZQ5F[*JW4TJU1!">XA91$"?
MM&&L-@H.JRDZZ//#$/:"TMKME= /S(C^VK^USGL\RN4Z"MF.P\JAE&PU>)4L
M*.GK<.SH0=MHE74N^SBL$?UP&H8![@6EOT^DCJE1=ZMZ[VG3K;>Y$9X8CYZ$
M2?8Z@F+$IY.^@(PEQ^P%SVKO8LEAGQXV<?,%Y<?;"G]J:%V?(#H]SQP@XOEF
M^)H012;/&?!<?-T/X<"1L0;+O=/%.I+''N5Q^Q,P#&8O*(-^"D5,#;97DK%;
MYT70O]:_W<[+(1+=RD3@VI#\1$KD<QI5]Z\K\D*=MW)8Q=SSWQH&H1>4/!]9
MO%.CY<[(J_5?'C\/MR<P&&MX2:6.^,C$(Q,)8K0>O"NH;"Q&Q#T'1>U'P#!<
MO<"<>DM%3 VV]Q=?<7ES>/RV\@;)HGKF'=CLZF@^%NI9":"=K]7+T@0<]JKW
MR >&@>4%9<_'$&1WRWQ^F<WQYPO\5C?5E)BCS2 ]7;(J(DDH6$$1:Q#<%>?8
M_8*3)KM\K@GJ:0_"V$N@#I-Z=^"YO23[$^D&\\9\AB](86@4'LEI$YQDI()E
M$.C@@4L^R*B%4_H4>'J*QIZV_QP(B2=A-II^ND/>=A?RU7;D,VU<R,9ID$[D
MVN GZ8R* $R[A-DK+T,\ =;N4M73 J 6Z#I"!]WAZ9_S\&VQO)C]-^:ZX;@R
M]&&)WV:7WU[-\_J/KE:789[PS6)UL?H-+\XRYRS;NN$Q<#H^IE!T6HA=$[D+
MW/@DPRG60N]->$_7:@M4MM7D_L#U5\"=XY=J?T>![K]C_D(_:A;B['QV\>-=
MF"W7.^'7O_[F\MOE.>GS._X\3TL,*_P)K_Y^QKV2W-0T"A,1%$</D7Q7X$XD
M%@,Y,+K-@M@#">YIQ=$X4#V%Y@ZVK=]Q&1<C6==UK%07\'[>+. ]RXKD@UH!
M6DE14I3D:4C#(425R9-F"N^/9QD)? ](Z6GWT3BP.D[:'5S&=V@O4=0Y5P[0
M!ZSS8W0=#*E "2Z8LMKP5)H@96^0G*CF9AR0'"SCP_&QN CGH^/CS>6RBO#,
MU<%Z61*FBR=_L^[8]37K&^L\JQ2EL=HWA\F&F)Z6%HV/ED,DWH6C=)N)WQ;S
MM.&#^=IU6!^64@J@E-+@C'.0H['H4\HVMC<P-_3TM)5H?/ <*/<.+J6[DGD7
M$FXBW>AS'9G'('#.233<@[>:4:0;>=#>&25"$_P\1E%/6X=:Q'0'RG[JEY>;
M9-NB?%C.YFGV1SB_XF-1U@\)%U_#Q;?P(^*',,O__&,Q?Y^N#DNB_^3-US#_
M@K/YF\7\@LCZO)Q]^8+T8[Z\_5Y/4XJV!(4.6*QE/@P#1),0K#,\)&:8U\,>
M YN2V=6ZHN.PV9E.IT9W%>W;O]*:H5<YSZI.P_F;L/I*S*UFI-BUFL\24GQJ
M2<K&%Q*UM^0U!%>+(.D$.YD#XK!&YH$?G#[M6O-.YXO5Y1)?18)>2!=GTI2"
MA3M(S)&7S3RO0Z B6)6=8H9+EM5.O+60\FC(^?_^[8&,Z8C]OOZM]>_4_^HC
MEO]1__[/CS_?^?G$'L[_5UI\N_K9[V;S0*=I_B4LEY79>EY7/^%%F)VO/N-?
M%Y?A_"[]J]FW/\Z?1<Z0'_MO-P3?9V7STQ] Y%CBZ==PGC'_S^-=E!UHR\X)
MCBQ!4F1!5&(*/ H)'%%%Q60)]WLM1W10'M(SKB-V]18KK':Q: I#M)2@0L[$
M(A,@O!/1>J,];Q/][2!F^F?$(S'PM/>UO\ GO)I6RXNSCVMC^==L=181(ZNU
M& SKHF9)5ZGW7D.(CHL4148_Z)&&?NHMA-"_W4?'G<].CX>CE+<X5I(]J'_;
M#*VESIY)<"753:2!_+Q2#'"3I$.!S-YO33@6 /L,FQ\; D>H[+[2#Y#?Q&K_
M=3:??;O\MMV&5GBRF(COG.*F"UZ03RUX-EPQ73)/HRG^SJ<G5OTABEN,(<6I
MU1_^ND5XJGM@N4#2EJTSZ".C^$X)L"$FGR5:Y0>Y!\/4?_O3TX0?HZG_8"EV
MD+"K:<>+3=KQ,_TW:RO(E%<<50'#/?' *#J*(=<8+"BGBA'.V2:.XBYJIH]-
MQ_ ,1I-WAYC9% DSR[@.T9)>UYV;!6N\'H"KHC4= 26&^0U'H^:*GFD]RN/U
M_ QP#A!Z!]!99_L^A!_U''U>O [SWZ\'QU.T59RR$ *S%'OI2-979>"U')QQ
M5H=;-D'/HR3U!:!#]+UH(?P.4%1E\@G3Y7)V,;OF:-L!)[T*-@HH1=(M+C+=
MXI(K8#E8EF0LQ;(F.'J"J&FOL 9(&DL!G6#IYH)?FVFC;,Z)&2 I!'+A5 )G
MDP,Z&]G5>7(LMJGY>TA+3Y6GQSL_1\JZ.[3<ZI!20FIK))TF:PQ94)<A:,[!
M!^^B=99EIT^ F1N*>DJH[:_I)X%SH-BG?OP[8CR%QJ(I^BQ@M0FU-#%!+!BA
M:!^3T9'K,FQE;>-I(:?OL-\+ ",-"]E'&Y-6%A\W2L![HVKE$6I1#;U \@[1
M@\Q>Y!"+,&78//:6,QU.WX]_/. :ZF%J$W=H;SA=#+%$&2#%.K,NVPS1U,E/
M(9MB>2'9[C?HMD63_NE[] _&VBGT,#76ANVCXP99EEZ0KQ%+'>P4P2N*<0T*
M;83BUMI3+_T[??O^P3@:7\93HV;PYAY>F//,9,A.UHE@PM I4 :TDN3$6N1N
MX,S249<DG7[H[=$V:%1)]P*?YP:*FQB<=S: E$: \IZ3(2V*3@@%SRYG'ZW=
M"SUC3&X__;C;H\$SIIRGQLZ @4R*9>-$,9"#2Z"45R0J#."%0F1T1FP:5O<Y
MTKRKT\^S/1@Q(TNWNUS3+]=UV%QA\E%D,(J KWQ.$)15D#*+)BM-I^#>AIH.
MALZ<R.D9.T=YF-2[ \^30TU2B01^DP"#J'4/A4' I.M?!#HM=6CTVO_2A\[L
M!8G#A\[LHY^ND?>V%$P7-W%$92X8$4/('(1.Y:H_DDPT&6;ND!65#?I3Y,V?
M(;.G7%1K_!VKI>X@>*L33@MO9.(.K YUCAV7$'(A9R-F65MQK6&G&$"S9Q?B
MR2?+C >L V4_M:O>MF/-QB)L,@C(L/JX!)> UD#2) 4G4PX#5PQ.WX5X\DDR
MAT"S,Y5.#>Z[HOV(&;_]4=5*$IHM\G_.+KXN+B\^A!_U=]^77\/O^)]?Z?.;
M8YRS4SQY.L%:4\0=F87($4%19.Y,=BC$,/ >149/R;(1P'DZE;R</L;9QB=9
MDD^R^C/\L;JX:@I<__KLVV)^_F/3+7B7MR-Z'/?X9*/^QT.9;ML;:8WW)6$"
M7H?^JA0]Q$3@EL4%+3.*P-J-)3U-;Z3CO!1K,J"OS<8E. A22D@^*-3,\\+:
ME0V^A-[(?3 PI#=R'X%W%U*L"YJT-)IS;4FS1=31+!27ET+&/[N(RIAH5%=E
M@B?MGMQ+O<^7">XCZ^[0<CN]G32/*1KR$%"#$K7'R#H.)3KR%%&E@J?(M75<
M)KB7I@>7">XA]JG=\^W3UW8OVH/-0G*[62A$'UWB";(O\LHDA\P0K.=DJYUT
M1@^K"AS\R9[0<JAZ=STSCBOK7A"TKNS9L7B/V+K>-VN,XQ'IC E.<2M/ IQF
M&J0U9+BE\_[^$/!G(/3\-WO*I8Z)H9&EW<$MMK.'#94H/F0)QF8/Q)$%I\@C
MS#YHE\EHQ])F)NW+Z T]QN\Y6MX=8F9SNA(1*S$[8*G4I<0U/\98@L"1*Q8X
ML^)?O#=T+ST/ZPW=1^@=0.?Q]D04D6=4&N)ZI;73#CQ94M*YMC[S2'+C3=#S
MLGI#]]+WX-[0?83? 8K^(RQGE8GZE'G5="TPK6<Q2!X8T5_'R!5TD)Q/WB>G
MI&\S>?0^)3V]]1U_61TEY\YPLCD_(OE8F*+SP\1F>:8OY.@SIJ)W*5MGVN0
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M(?T_KQOSG!$Z>@Z^D+Q5C (<9@FUWI!^71G9J.;B &+[*G([&; > +RMECL
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M,TC6EUHL%^O]G\ KD1/CW!5_ND:+O19=GK:JI#_O:S2U=@71';NPC)<R1(;
MM)>@LBUUY%RAT,EKI92G4]=F:]@+W82YE^[WV82YCR(Z -6[Q?+/L,SW5^D9
M43@3=:U)8'5$LE,0>'T>#;I8P760I8TCMIN>7H!TK+X?#I<\5OC33^F]-VWF
MU3P_[-#8;O.,";FV@N(>S^C0!4$^ 4DM:B49JA!"O(>J1]IMAG^SEX3L2,AI
M*?$.K-$C6QE]*8D+GX&P7WU)<BB#KFE"SJ5/I2AYOTVKP;S1%[$2\QAK-(+P
M.X!0?>NZN>_7=WVVB-YBAIB+!<4R!PIF%/"01=(^."[:C&E[2$N'):X].NU'
MJ; [$/X6OFW/)Y.2Z5@2,./I,"E)'!DRSRE:)654JC0:C?(815-[5L=I^DG@
M'"CVJ=>L??YS\6$QFU^\6UPNW]'I^H#+5+FID]=^ND3!)-M8YF1Y,=4>"UF=
MQ3IOUSGBSYB@C>.,12T'N5.#/]D36@Y5[Z*YK'M!T&=2.OYO7"X>LL6WH49A
M.H?L0"1&_B&B)M=0%/#,V*!(?"(_6U:_YS>G]LA;86AD:7=PB]7RH8M-^5#U
M,:_LLS B9B[)K\R)+G:=K_[)EBR=LQ&+:S<E\3XU@[!D_L7=J:/5V"$4-X<V
M*Y:<# S0,^(BU7!'^ *):- A*8I=V@2&N^F9>+W/T7I^!C@'"+T#Z-P>6?MY
M\3K,?]\F1Y0I2AB*;*VH@T*$9.#0,##"ND"Q<_2-T@J/DM07@ [1]Q/S@@\7
M_M0.U2[;7%V']0D3J62LFR.=-1Z450X<7?. 0F;CG0[N?I'?LPO&'GYE$##L
MO^A%-ZZ.>@7;=88OZFR9@G+U.$ G*'(ZG-Z;8G*R&ETY"FY37F4C:W((/@X0
MZ]0(>57CTE?S7'5:#>S51*"-794A1D3'(.M" G*&0S D)2F1^8S!JS1LI-E3
M7^D0'8?H<=%"J!VX/$_:ZU]N%HZR($U A&PTJZFV"#%E5N>PI\2Y,-&WV=PQ
MC+Y!('/_HG=>0U5W!>"[\P#/I)&,AU"'KM;-BI&O1XL[\AH%4\YGB[I-]N$Q
MBJ;.B(ZO_4<!=H0JNB@,?6HMSE9F%*/@1TRU_VY69IA_NJSM>[_A7Q=<_+J8
M7WQ=G>FD??08(,FZVTX: 9%B&/HGCC%R9DQLU-$["OU3IU^; W8"-7=A,6_G
MM>\\Y=?K*&^2TN$+GDGEDF8A K=8BXHR<88Z@4Y(D;>VP9@V:8_A-/928='0
MJC915Y?;<G8.1%I7+*7;%4M'K-#8\PN-9CP-9*F+<4\E)R.1,"1K.Y(-X%TL
M@(YSLG0Y!'="Q__4XYZNG&[E0DGD=A.)-M&QJH%B$9I$PI!S*V*QK2HQ[A#2
MH0/9 $6/>Y7[:Z.+VW;?X'"=O#+9>^ZY 9X4W1AIO;"XYA)2<3)9KZWJ90Y8
M3_.0#H#(T7.Z]M97!ZC<P<8F*T8^JU&2#JCCC(XJIU/JK!.0;=+2N,B8:=/
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MTWA_XO#[;3==KPZWC[)"2+"!262>"&"RPM7QR),Q3N=*X==^=/9#W[F<E9]
M5@T@\7GHD*81/ZZVV'I% B/*K!1#;C'T"!+#O25UQ*B32I9%RBR84^B[+;3U
M0]S9G8X/*Y,F6U,]%,BF/].!_:A>/./XKBRODS50#Y9GQ<$/K?5"C)8&0H!9
M=).$9A8,5VC4' F1"9><J+/3=E$T</GY_*'YD"H-W++R$ 7E($P,X+2(I;0K
M\"@85ZK.]=M.DIHJ0S\,$V]4H1_(_K/0'T>T>]KUJ.&U2<W&3CL!Q++.3GD%
MI*27""LT..LMQ&"",I3'0$[2+Z264EGESQ!C.<_&0$@!5VER+AX7!1^\UR$G
M8D,=%WD;-8VJDGV0\%9'E+V9/G()YA?D__)<XDM(4S>;=,MJPV 9H:4@2$J3
M0#!DBR=%UZ*7+I1T)I!>+;YZU5]N):$IJ!P@U6Y(%H^-D37=OT_GMRE,\B3%
M3::GIB)[6Y*?2G8>CQ%LRBA@SLL0<(W;IY<.[8>3762,5[HY@&B[H?G<"%C*
M_.W@YIL6/UP'G:+)X!-ER).$F\>45)&H$Q>1,9%[N?![(>4I#2/"9!C!;H'*
M$5QNX)#EW=U\,DVE1.R/N\E\<C^NU+L0,I,.LDG(%:85&,7Q"\TT>^<]=74Z
M3.X@:-Q<P\&,T9!L;Q0]Y>,LW3=DB9P)BNX<%2*7RO?2TS=QR)0R6BY? J]S
M;O F:2//?QT" #U =;@TQKY/_RU-4^<GW8=I6*O6D!B+"K>9*O<GPC +3G$*
MFDD9J?+4</<42SMNTE\\NCTL'"&W;C F-J!A=K70Q'U0)LXHB$G%,BQ2 @:-
M";C!A5CG>&:NBEXYIEEMM0SDP>W3$&QO$SV;#II,>!V)!$G10Q/<6C!62HA1
M$V\L58K5:1]^9JUJ]Q)X_U:U>W"_/1AM1ET')Y9CU'5V%$1R9=H0,<"#238E
M:5BH4S]X7JUJ]Q%UKU:U^_"]/?!\O+^'Q1UDF#(, L:,((3G:-1IQ#A4QQB$
M29Z>Y)[I8QO5I[5MV&&,']L+_OWVIUDW77QVW\L9UQ71VFOA+%@=/?(C27"6
M"%".:ZY$0BW]YJ72EN<VI3P.%%0W#-?&%O@F&'C?W?C):AKU_2RP[J%K[J),
MPYN@7-92FCG\[FH&1HS+$*+P^5%$,;]R)N"BE0+JJ $A(RDG4PZT(E'B'L,_
MNA=VJI'8U"'/ #!L0Y8-V,#U1IS_UJT#VPUGTOSG63<O+%:*6H%;DG"VZH'G
M."^9:L&*)!/')5:QA6]1UE1<=QPDJPBC 7!MV64]MM8_RZ=/^=/=(G0W:;[<
MD[],OGZ[\N6@WBD)E"51\M<(&.,#9&JB$ Q=3%_WQ'*8=33ES T#W!$%73_1
M:/V#\L6[>?K[W_X'4$L#!!0    ( !"A8E-GT6Y7YIL! /GQ#0 :    86UG
M;BUE>#(W7S(P,C$Y,S R,7AQ,RYH=&WLO7MWVS:V-_S_^RGPM&?ZV%VRZEMB
M)YDS:RFRDG@FL?W8;GOFK[,@$I+04(0*DE8TG_[=%X"D;K;;I#)M8]::QN(5
M!/;>V-??_OO_.3GO7O_[HB=&^3@1%S^__7C:%=_M_/33KP?=GWXZN3X1'ZX_
M?12'[=T]<6UEFNE<FU0F/_W4._M.?#?*\\GKGWZ:3J?MZ4';V.%/UY<_X:,.
M?TJ,R50[SN/O_O%W/ +_53+^Q__W]_^SLR-.3%2,59J+R"J9JU@4F4Z'XM=8
M99_%SHZ[JFLF,ZN'HUSL[^[OB5^-_:QO))_/=9ZH?_CG_/TG_OWWG^@E?^^;
M>/:/O\?Z1NCXO[_3ZOB5/(R/CV0_/CA\=71T?/SJ</=X[\6+?74<]5\>_^\>
M#/(GN)SOR?)9HO[[N[%.=T8*W__Z:'^2OYGJ.!^]WMO=_=MW<]?EZDN^(Q,]
M3%_3:.'LP,"WN=.128Q]_?TN_>\-GMD9R+%.9J__[[4>JTR<J:FX-&.9_M]6
M!C.\DRFK!WQAIO^C7N_AR^GGU(T&GI/H5/G1[>WCD'I?1KJO8:[:1W__"2]?
M\4EKA@H39O\Q?]/R;$@[A GIFSPWX]?[AS"FVM,B6 1E'^C+N[W+Z\[IF>B>
MG[T[/>F=79]V/HK3LW?GEY\ZUZ?G= (OZ)W 47']X?1* -G__ FN;(E/G<M_
MP8FW_Q8_?/]J[\V//_X(_QZ\:8D/G2OQMM<[$^>?3J^O\9)>M_/S54^<7@MX
MPMOSZP]BZW1;G)U?PT.N>Y?XUL[9"1R$HW#%]8>>(-ZZ_M"YIE^7O?>G5]>7
MG3/X>=GK7%\)>,?%Y>DO<+LXOYS[@/8/W^^]W'VS_-^UB_L'5FC%@C^.I>Z\
MO^SU<.%HIB\^=F!YWHE/O<OWO<O'^#TQ23^9"3,0_RR2F=@_:I&T>XP?TY\)
MF<+7C$TZ?(SC[WQZ#^Q^>M9MMQ[C\*]__I_>R;EC!G'U\]O6(_Z6WEGO_.WI
M^2/^!&"%QSALV#6O8?/JG/QR>G5^>24^?NRV4$#E(R4NK-KI)H9TM0\FB97-
M?OC^>'_OZ(VX5!.K,ABXS/6-NN>'TY!J'_Y;D>5Z,/O+O_QPY9?_[S?ZW]+'
MWV?/K2N:$\-J]FNK$IK.M:JGF\?=ZA;9STQ2Y,NWW*'I50.ZG\9\6&K,(^M'
M,Y%#M=,'C?[SCAP !;^6R53.LN_^D%;]9S7215IZ6/'5>?NQAYH):IZ@K5S]
M289X.'N"1Q&KR%A)A%6DP.YXU7?_N(!UON<'O9S@\'/93U1%LQ:>M .?D<A)
MIE[[/][$.ILD<O9:IS08NNG-_.->P,AOE,UU)!,W131./EW14GN7Z2D'(LIC
M_V9WNDVG?LKCY7.O#MH'N^M/[[;WUIZ[[;&'[1?W?.I/-&(>-4Q,-I'I?W]W
M\%W%87$,PO?U_N2+V)LGE40-EN?&3.:9S]V_@Q>_!D,1Y],?(UIS!Q]( G=P
M]$ IIVWA;;J3WKO3LU.TXA9XR$_E\YNE_143\;SIYDI%**/$7KNTF[[M,/;N
M-8R[+/:'F)H3-= IJ099X)_ /W?QSW[@GP7?(C!.;@N:G\! CH$. @>MY:"#
MP$'S8_I7:J:)BA=-AL ^@7V6%7_0_#%0PC[,'[Y_\>J-Z'X\OSH]>Q^HQU'/
M8:">-<)W/ZC_2XZHD1*?E!TJ&_@G\,^=_!/4_\6DBL$ )H?"LWE@I6_/2@+_
M/> ON]?L/"Q_'*RC41<58XV%B4;?*('#*.<HT,G7T\E10^GDX&".3@[7T@F.
M=0"CS17*E-,T,G;B0BR4//%VELAI*6^N"GNC;S#<VJVN"P2U_^*Y$=2+=01U
MHBU<9&Q&U',^ -I2-M!/H)^#.;,:[.K>NW>][O451J4K$UN<G]&O;N?B]+KS
M45Q=GW?_1;EUO?_W\^GUOT7GU\[ER54@F6] ,D]M2KQT.@AF]XJH 2QNAK,#
MDKAKQD 9,W$UDE9EK"->8^([I<#7+CB?A$!=X+G[\5PPU1=YSB4F7L@9\A4K
M1+TOT4BF0U*V:[IW8#'/8D>!Q=:R6 CE+7K#LER/J6+A3.5<CX6FA9SH7":B
M$V/^+NUIG;$ITMQY0\J;/(>>H/7[#A,*8W&B^K=?UY79Z-8+J"Q-\IKUODQ4
MF@7V+MG[.+#W6O8^#.R]$(5=9.# 1HZ-7@4V6LM&+P(;+4Q-;J+/(RJ/62B+
M\?L3;7Z!N7BZ#O8"<ZUEKI>!N1:KW)U!UQFJL$$%'KH'#QT%'IH?TT>3Y75O
M2. BQT6A,F ]%QT'+EJHK-$9*G;HAV#'?F"CP$9WLM&KP$;S8_I5YR,TEO0B
M9L@S9J!0('!+K'DW<-#\F#[I1&6Y2549^@J,%!CI;D8*61M+8ZH!P 4><CST
M,O#0>AX*61B+!4?R2Y7;U&X'+@I<=%?-YR]M<=F[N.Q=]<ZN":_SBA)0?^U<
M(E+F::],6>V>?[KHG/T[T%2@J3LD\V%(25U.2>4" "7.[5"F^C]<<^(*!5P&
M:F MQUHA+6X]:P6=9W%JBGZF8RVM#D[@P$'WX*"06+H82RF4Z!3YR%BW+P4V
M<FP4$CC7LU%(X%P8TR\&U+M+]7NAK0KY99Z%0O+F>A8*R9L+8SHS8 NE@T1'
M(;DL,-#=#!02-!?&]-[ VJ;H_94)LE(6 I*!E>[%2B%/<]%EQX5UP55WVR3]
M78J158/__N[[NYM6''VWV=$M-5%(#?9/0*-._B-(@K62(.2:+C;ET:E,(PT[
MZE4N<Q62?&IS<[@;.&DM)X5TTX4Q_9S&.HL2DZE8?-2RKQ.=![=]Q4RAD.B6
MF')(/5VL) +F&5;@A1?61$KAP@6&\@RUMACB)VIPY8_7OJ@9K> :TM8M-! +
M#<3^E*P."4!+"4#C2:+!C%!BJO.1^"BG#HMNSF7GPK!!*;J/# ^,%E*@5X$_
MYE9&N>.N,R-.U$ 623#92X8*/1AN8:B0';1BYT)XU+<J50.=BXM$!I#4DI="
M%O@MO!12A!;Q<T )-%0E2A;[1PG6E+@DXS(@#U=,%>*TMS!52!I:+GH+UI*?
MC!?!A7P+[X1\H84QO;7FL[)@*QWO[QV]$>]4X*22DP)\P2V<%-*%%L9TFF:%
M1?]>X)_ /W?S3TBR60IF1@0>WQ(7RHZUZR Q5Y84MJ; 6O=@K9!ULS"F2R43
MS Z8P!*'S%7/0\')<$N1><BU65+O<I4D,$%%X*7 2W^(ET(NQ*(7/+W1UOB4
MAT\RSY4-NIWGI5!S?@LOA72'11RO?J8PJ0@[[%%KAL!(85.Z!R.%-(=%1AH,
M=*(1H2ML2(&/[LU'(<5A,:)DS&?VW5UBY64<^,A-S,M0*7<+'X6LAL6T.UA:
MJ5/QMLC@7):)"\QJU5%0\ )#W8>A0JK#,K;0B>I+.PZ=ZP(+W8N%0H[#8J8=
M1F;3$@_%;U&=H54!%6&.KT(6WBU\%7(?%@%&BC16,6Y/86<*''0/#@HI#HL0
MQC*78"'I&QG-R/D DU58'4*T@9_NP4\'(=UAV5@Z+_),QXAHS'7K@9,<)X5Z
M]%LX*20[+'-2!Q8*YT<FP$P3JQ"4E1-:A;'B5VFM3 /B0XW#0GKKNG9=]^K6
M]?;G?_<NZ?BGWN5[^//JY[>!M@)MW2&]7X2V7?=KVQ5X*?#2G;P4,M5"EZ'
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MF2I$7)95/W0,TR;EVEM=Y2;Z/#))'':JP%3W8:H0?5E5@WEIS%B<Z.QSX*'
M0W?R4$ "6()JST#!B_+"PEH%%G(L%"HNU\<H%X.45/P5*"=0SAW"]RB$)X.I
M_8V9ZJ=<]A/EC]>^R-U_A"^8F(PR=%Y;ZGMZH]Y,=9R/7N_MXL/K=_5-GIOQ
MZ]WJ%MG/3%+DZV^I374$!IZR#S1'6L_/$?V'#_1QHN;FK_;?D:V(8*AV^E;)
MSSMR !_R6B93.<OF/W>LTYWZW"Y.RQWOK#])VB$\S$WY2R(N6LUJ,2R8QCLP
M@8F<9.JU_^--K+-)(F>O=4K30#>]F7\<$O BT>-"\>EJU.U='KD3SN[-[G2;
M3GFVFSOWZJ!]L+O^]&Y[;^VYVQY[V'YQSZ>&+86WE!"H7[2)M87),5;\\/W!
M\1MQ/ACH2%EQFL9JG%;!$MQQ0@/!H+S=G]-"-'^QJ4S56OTKXXT"_SW@M;\7
M_3P(<U0UCX$M:M8PF,/_/#\]NZZ,XB!.'<6\".)TC3@]#K;PTM04DXFQ%"&[
M!JTDDU%(- R\="]>"D; HFJ21=9,*YCLP$6.BUX&+EK+14'!7YR:*D&C],D&
M3@J<="<GA3S=);AYFX^0BS+G<0JAC<!'=_-12,U=;(<BOX3<]L! ]V:@D(8;
M NZ!J;ZIQ_?T?S#]Z>SDE+&PK\_%^=N/I^\9&CO0#T_6<2@X6B>47P7/[RJ0
M!LV(.;D18"B(\SZLL0?10>B&F;(M\4G9(1@15T6?Y#=>Z&HI M\%OKN3[X*7
M^$_Q'?%:Q7J!U0*KW<EJP97\1UDM;&;+'!:RL=9S6' Q+XSI5ZEA<;F^UO,:
M ZR\0QO?5A@1Y>G :('1[K#VP=B_[EU^.CTC^SX03""8.R3SWFZP[Y>B%E43
M]\!!CH-" Y%;."A8ZHOY7(.!8A33P$O+O!2 3->J+Z=M<7IVTOMT=OKNM!MT
MF$ U]Y+ >T&'6<Y.MS?Z1B8H@Q=A_M%!&G#^ X/]$08+*L["F!8+5'WX(;!3
M8*>[V2D$'.YFIPNK=KJ)R6#UQ(< .SC'7"'?Z1;F"K&&A3%]U&.=9P)F9X'-
M C\%?KJ;GT):^PH8]TCA'O719"YJ=SW2-A87TN8ST4VD'H?-RC-7Z#ER"W.%
ME/<5-2/75LD\% +7>"BT&;F%AP+0]!)([EC%P;<7V.=>[!,PII?F)M\Y'PP"
M]P3NN9M[7@7N6;2.Q"7^=,F+N=7](C@;JOEY%3+Q;XOD[@9^6N*GKK91D4@K
M+E5D8*U#SGW@I?OP4DB+6#*,$B4S<MTYS+%W11H'.RFPT]VI::=M<75]WOW7
MA_./)[U+<=F[N.Q=]<ZN.]>GO_0"!04*NDL@[X<TM27T=Y7!DE80[Y=JDLB(
M,"!11M<1[>I9;#<! C[PVSWX+62M+>YF13XR5N<SYC8\4Y;SKF<VCG!2%H&O
M $[AI^QK; L?6-&Q8NAC>(OR!-K3I].K;N_CQ\Y9[_SG #WDJ2945JT5X =!
M85I=-AZ8)S#/W<P3M)^5>5O!VQ.XYQ[<$U+T%Y6Y#&WUD)558Z!0XW(+ X4T
M_,7@0VEN5\G"(4DK<-.]N"DDX:\.Y07N"=QS-_>$+/M%A)8O$Y5F8?,IV2=4
M@-W"/B'!?F%,[S$+*\7*Y(]R&GCH+A[ZB7K>^^.U+W+W'^$+)B8CG,O75B44
M=JK:WO]M?A[Z)L_-^/5N=8OL9R8I\O6WU*8Z @M6V0>:(ZWU_"31?_A 'V=J
M;@)K_QW9B@J&:J=OE?R\(P?P):]E,I6S;/Y[QSK=J4_NXKS<\<[ZDZ0=PL/<
MG+\DZJ+EK%;#QLKNP PF<I*IU_Z/-['.)HF<O=8IS0/=]&;^<4C!BU2/*\6G
MJU&W=WGD3AB[-[O3;3KE^6[NW*N#]L'N^M.[[;VUYVY[[&'[Q3V?&K80MX6$
M(I-%B&TYJ8'^=DV!4FDB;1YTLJ"3W8.A0MW)XMQ$(Q47B<I:HO=EI/L(><%]
MLU+U)5@Z@:ONE7 0RD\6/05IKJT*O;F7^.@H\-$M?!0R=Q;#I\ \,3)0V(D"
M!]V'@T+ZSL*8+HI^HJ.0<1P8Z'X,%#)XEB8'5C=D[0<>NC\/A22>A3']L[ Z
MBS7-$+ONJDY><&XFKJV62> NQUT!^^\V[@I)/4O.AH&Q4? S!!:Z+PN%S)X5
M^)F=^$9'(37.<U# +[N-@T)RSZ*?P>H;G:AA8* [&6@IL6=M7LG:C!(<PW?W
MN>WYY0K=/.I4H=K";G;FF/UB%1GNHORZ2&-E\2K,>^7(\!\GSLUGZ-)(14?\
M\/WQ_M[>&_'.V#&:F;]:G><J17#%;$E1;O*GO%WZE"X*1NI&09A<GY0=+E8W
M-_F#NG=]T&D*1#AQ=/AXONMDZ;L<6MJ:*'"3OZ4W]RU4?@7:C\'$$(S(J=@!
M#V4YK!D<+*L<Z?A'T*.!RZH/7Y8<7[7E-4<RKDR3:=XGN('6Q.+UV=N=%\<O
M'LO *R%X80W1I!07<D84=S6!O3K.1DH] @;CSZE$X"J5O2^CST-K@,QVW+ &
M]+\W&Y,"H,9I3%:&R1Y:N=B5I;GS6HE@%$VVB/+"8KW!5:XFXB*1CV WX0^I
MY.^5'$]@)<Y4+GXU]C-^35=.="X3^"H0OBOWE=ND:[ :5LSZGS0:\$MT_-_?
M:77\2A[&QT>R'Q\<OCHZ.CY^=;A[O/?BQ;XZCOHOC__WZ+L&&AIO-C_]1W]T
M@WU_V>M]ZIU=B\[9B;CXV#D3Y^_$I][E^][E'V#F^I?^5F2@;<[XD(97I?GK
M@Y</QO#7(YU5FA+I3RBI*LU>;.5X"0J$_8?T\=RZ3(LJ[D/,),W0WIOMEHA)
M*Y49QQ>3F=@_:HG]W?V]EH"9)$J'\SK-C>@SJI\<&Y"LG?%08;^_J-T24IR
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MF2J-,2&.@#I1!.+U4Y4GL++TP%3"@A#F:68*&]'CU#:G3?#@_+R+7*:?\?3
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M'C(K"?7!E4BC8,:$?@38'[J"*-Q#%EXY]ZY9:PZ.'GL)*+;-44N!<0C41D!
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MH#*3*H.AE]YH:SPO?I13S#^HC6C%0"CV/P4!PJ%?E_?@[21"O1R@"K5=4_)
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M"'>R5",<@*S"JA!VE&%:]0QK[A,<.:6+GV" "O,D_NMHMP4#Q/^'37Z3=$2
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M6A3N*U'X9(6YG\ =.QA8Q03<VBWPO=A*BOY*U=17Y5+:;49#V&HT45_PS#6
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M/8;E0C473H-"B^4TIF32[=*6F.<<E^@, IY\'86KF.?A*Z==:X(J)>UGJOK
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M>NP%-KJ1(HF.5-]4'50V;;!T+W>@V[2U9[DQ7%]&R14QCYSY,5(3ANE.F9M
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MLUA^<W50H'6X9L0^SZ5Z9HE-[)JX4)&K<_1@!1MY 0W.&[^T)09P0VV<D9G
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M6IG=^(C8A5TYV,=/\VU)G?ELL  #TR!@?);CTB6L*Q?EY+<VQ,)G](VUW%8
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MU.;1&C^ 7ROJXAQ'*X%\8X]D>@F.RH.9A*)+ME2OB<7-3PMJV1)X >J3U/T
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MLC1.J<4@&EG23 !O%V=157%T79>-Q5E3\=_JL_Y;9[(;2YLGEAK^<ZGJ19'
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M6)NEY1)? MN&S',X()(@IPF&R]P.3[A^R)NLE[!26,+E4J'L(&=G#'.$1QY
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M^[9)BP[>Z9^9Q@WA%'OO>%K.798S=]M.;MI$8 ^I"%M_(S#7T"2"SC@!, P
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MUWN"C<$G?.1"'T^9(9,9^OF4&?IFDVD)Q$9OKK&.!_6_=\8M-* =W-%&G-$
M) ;C$(?N/3\[K'-88D,CI-TZDGS>9A"F WW7E1H"]O9M "$&QY/3XZC[IJ_T
M7;M /LB^7B%1?3Y_E*D9K]Z85S@=7.&GER$\&_\GX5@$\U,,,F2X $8^?@J?
M/7T67CY[K..,$3%#]A:A;J-3?I@7<UBS/#S-5T_#9Y<_A<C];TLG;DLJ,X!)
M;$_XS^VK+?.*MNJY6\('CJ1?/[KHWBWB^B@)7GWYBG$6$<:C!673F,R +KL#
MNGP:_OS\,GSZ\_-O,JXC4;].&=O 1%B)Z4^7G%U/OK2$[9%;PW;V@N]#%6Q.
M'*KB.$T'<PB_N)GTE:UU&"O:Q5L4I])_M4J]W(>U(KBZ@*P#2]Z1,U%^;_L+
M]H:$_3HV$_YE6EVN9"-C\N7$V0+VY8E8)+56H^LIJH2 6H1A)^I,OTI4(!Y3
MK+FJ/JUUKX"WQ&8X3N.L;>0_ VMB)+0)X0Z:C?)IR(*CBT07TM1KMG77V22C
M890I$0/?Y3QH':QT<4LY!@N5);K:K"39MR0Y#DB=4C@8R*<]AQY*23O;E"&
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MR)T0![Y%D2BH53%BARE,6-5VKMMS%NC2WD8.>4GAZ;FBI\&ER\(U';IB:8I
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MVY]7T4Q1JP;,=F(4U"I3^YB4\)\DBA@8J)MD[?FFW)UBN>3=7S,%4BM=:Z8
MYI?(%:E+RN"DH3_W@J_2[Q1Z;QCRTKFN-F[4.U-^_K6;0O?"\UC>+*]DFZNG
MXVCPU.CGF \/S:S0#O9+$)PQ&!)\U+JC,IP_V5IC"JOAJ)$C^QSHH-*3M"+Z
M8D;RKD 5UQ,I_6>T-5U*6.0!8<2UWDT:7>GK*W5M*LN<V!OG:(D4%3):'1)*
M7B<2;]TE/Y,ZF+JE#-$6F$5TYL,8-&8K,#UGG.T_G#3"<NEN_Q7WIWV4B0-!
MQNY;?DG8J]+$/QAA)TI)4V5$T'#I-SDKHP:]#I)I_;TLA@3*!RP-[[SOFT$[
M$?2P%AS7HN-V>=JQ'-+#Q<K71('I'&)XTE""%P,IZ3+*NHI=0_ZG8+MA0?SN
MZMU8VQ*+*A4'MD/G&6EN5[##0;L90M J76[W01&=_RL&C-]&4U2\>/S=2K38
MU.:0J;)LLKG+%8QRHOM8]>*S/Z8U///R(@QNL;/,T^=Z7BA%0^18\,%KH<Z5
M_<=.B%80SM@K4^"Q:G0A@S,24@E\NEL,MM_;I?7ZI7-+8S_(E4PJ/',L_H'-
MYQVDXSY#AU9Y%.?ID:B5V4:U8E1*C7MY#VID!^WAFB8N)F'RA6KE1K^S%C=3
M\<>GLA3E&C;Z3:DT-QL&"JE6)IV\:&#MM)G!N/!(LSCZ:J@*GCX.@Z=/X'\_
M\1.O+BZ_2C'-FS2A/A.5KB'>64\5FI2"[8U9T'?HT+M5&Y59Z PB]#7;#DJL
MY2)YAES;4QB_ANL(W+CUVU\OKW)UC'F5T9Q \XTGD.\<.J6[%@;T[0ZE-IE6
M.UA!H4CN9S]P"\VPT!/6L&%J[\#;<MY9O28O[)U5OWFST[:"2WL.#%O$_BF)
M[I<'2+N\"&[.7Y^_/Y>SZ/*"R1TN+R[Z3@9ON<* 6,(1^U!531D1VE9_A"=>
M662"=ZP8T[&*XD_1G/[4_<:Y<)&!+W)V4@X CDZ-SZ0J9*P-QI,+O]Q\]CS<
M3#Z$4Z1?%,9]E!R6HEH,*JIW6*[:SHUT6QSG.^54O"(:73IC*F9ZM%EO"(<4
M#;*),C.TB'Q<2KMDE<_A=HD&*6J#3LI_B7/A+BV:"M4KMA*FB/\VT+-ME(SA
M?=BUTB0@-HU?IU')D&^3U*D<F)'UST'KH&5[<VYHJJ^NGD:=79TAJ+YL,B$8
MU=IN-Q-20Y\$CZ,17+HQSH)3@C$JZI7&4?+HGERV1E<%%U>7CZ-'S_"F\N>#
M1WO<X:OA?F3M'%-/QP>=4J(L4ABTFS[H3'66^9 \<D9P=X#-B:VE2-14?4]9
MU5T@P2W,[ZZ95-I%V 4=,\@#IH3P$N#7(!?<#4NC00T6E+&?'AXTU%T5W'-1
M]3ZB:X.$NF*%CEO7V!C(SFPW=!R+;)<NRSUVD9/UOKDV:Y'B\N+,XD!=0\;2
M9FX((KKR,B0N.@5Y'Y4Y_@B^!M,<[H/L##7&I,TG#/QD(4,(:D4T,PE#%/RL
M=KNXB!QL40"Z$*F5S308TYW1EJ%-:J8YS3>*MIM:S*3]95!,D2!"!P/L%+W2
M["H4MG]C[_+>N<MKK&+!#?#D^57E<\W:YS)JL&VXZ@4-=0XVG;0,,GZ,$,)B
M$8_I7GW<FO#/731AUWP(A-]KB_5 41$LZLK1?*@7:9D\XAHOE .$+TL.OV3(
M,'RO^6,)\>:VB(B0';1&2]*NZ2:[(RX>B>*J6J .:A\#0@E^?.4 J(EF5RP'
MKN$PBL]3>54#>WVMM:%4195U/Z:970<_C=DG41HZ:W*4&A-%V>K-N"C2\&@9
MF-24=CJ=T-B 0AW2I$[15M3KWMIP(SFAF]Y)<U##^8-'"XY.VBXQF; H$-V4
M45.C:V9F+@O9&68!PDHFC+O7!V*W,R:*$JP^9W\18\$<Q:Z7QN"V/OK;CPZA
M!K.!Y8E\MZR0HA#)]LE4Q0PMF:^2E+XK!*N/"@N?F/DFV)9Y/?CB\LM#*RYG
M[2,5Y>^*X*6:10@L.!61?\\B\G%*@XMROMPKQ-GIW!=MLC5U+RT^"$26 ]-M
MD^ML$U6!5SZ5\%\644$/ZF[-_W?V^2[5N2PL&PGYE@?0W^;B<L\=6/L:3^>G
MBA&;V7ARC)F-/4VFM&G8UNB7 PM]O1S0W[.6X:;FS]8SI,QN10H)<?E]/F0?
M[X/NZ6$+D0V[GR1-L*L V%%6;1$U(6(QV(RDN"2]#QAGZ"4?6J',U;Z[0S/,
MU9X*GF_-V9)@58#MG:J#F]S]=C:C8O;1UZ^_32ONV<@B,(I,S0[M=\,-V/^0
M>(S[VHKJUKSD8;7>W*,\0S -J)7$0-Z616)2"(:LE!UP]1D-K&T*%\S<I\]_
M>8C1OL*F9_G\4:9F;**/V8P?#JQ[VEWK&9DJ[N.,;CGRN\S3.V)<-HV&$B)9
MI?*>"J,IU<2W4Z7^7:S5DSWZ@,Z!D4^HYV33HEQZ4E$I&,5V[PKLN&!X;.&2
M'#LN2V-[S4SD-/"9-65N$%RVV] F<P!6;XE\@"0H#^'=):_\>/?5\,9R8Z3]
M9MP&;#WB'M*\(6B#P^Q,W([<:JN2A3?L#]*("IDMBC5S/V&@M\RQ%5KHD=T(
MEQDVB+0]J6!ZX+9%[C4=6R(+-?8VS&*)GTXC89R58)G*&\4Y VHJ F=J"A_J
MQY2V^*A%N-/WN)4J*?2'1LV26D9V<T['+4W?29P<G'VO7$G!B!?H[\G3.>%V
MSLUCP!T?NM)INNVX@S9%Q&VI3&Y,_^PW+1O!C>8O,GERM!S@&Q&OZ-Z\6Q40
M H'._C0_<D&Y&Y03A6F;/,;I93+[[4@02DK B6,S,0S7JO2Z@S]7%O>"L\HT
M;2Z>"+G2!PB<#O5<4%DKS#K)Y?:F6.#+%(A8ETZL^%BHZ[>=TV[JUE$?]P(/
MKR^M5.JTX\"^F3[WWRTXVIR^P'\9+GUDOZ^XS(S+U>0.25JUV0.-OMAY.8(S
MQY <9OK7@^G0#=O#S)@M>,'G6+H ])H<+KM_KQT+M["ZTLE1>9-6>C/@PJ(X
MJ23YKMIE@#03Y)W.7&=^Y)(Y?$1IT8Q 1TB?5TJ/H18 %P]$)_:80L&JS:C@
M7N&!(WE?%(4*?I69,)AAU<3Z >PH[5%_\KH;+Q''T)8MR67;/>.24X0T6%9H
M8'E340766'&EJ#EVZ(V$D4">J2TQ#8^CURG(BJEHL/K5CET@=I&(/['L-P!K
M47+U-3K\\S1&7SYES*_@$7!=0B;IX!TID(3*IY/-,B[YDBVLN=9$# J7"];J
M%B*(HI$X(L"]T>5(<S5FJ,?+6$A8[16V.V&9<'_$_8+I(,T(1$:7;+78>DTU
M^LX=G$"@.^+&;VQUO='S=J2;!>^OE\AX>OB)C$-3#5MT@V Y*MT@F9#"J.X;
M_)#F>%.6A+:"CG>PL[J#V?#7C%1\WKP2WB%9@:,NE1BE0L8^0F;'"^Q)+QUL
M2"<9Q:L!>]IX.^ZYW#*5FM="%+6H:%VJ$H'+<R^,CO#^);I0!EWVEW5X/F\W
M(A@>-HB!/_;Y>< $B<0A_K,-+1=VC"A8<B]>\>R8VHS*&&X8'"\3^B#Z]4.;
MT5T,5^+,@+E3-5NCQM/H]SV(?BD#;<CF(-B C&!&!#]^:IT%CJP)[\K9Q<1F
M7-P&>)X'N]G_QL0:'9B=1 W^]C=5SC'WQK42<H?K&6(L,=0S 9=V+04_P=G]
M@OL#3]$MRSG\;ZWB6:H</PAC.]TJ>ENX4$RIPH&YU?"(<:*%I37N205R*,D1
MX5:?(\V*2_PPGN>],R9^VM1\FT3**F<8+ZM3*4$4JB]ACT';W_@1 NA-"D:,
M%E2+KQ>S+E/!N3N!B!A$'B25(B!;G^.\ST2'9IQIE*6!)TH47>)K;B!?3U,/
M^WL?/U -.UAA;N#LDJ5OKK"":07R!GZ,4QWSH'@SRE'ECM<+0F$]U14_S8A!
M)]WUW>2[IW:F%=-VIQ,[0KZ8,$LR.V8"%5@6%9(ZW15H5C+#I*ZF+:PMA!R%
M],($8/<8*/BK&>V)%(.BDX>0:,,4WDRT ,*$IWFZ;):H:\!"J]J\%:6W4W0_
ME)UWS+$?J\.15ATMHIB3+A:4Q#@8PM0[8??XZ$[AT2\O!G JVDE>6WI4=X4A
M6"FK(2V62#JB)<=YQ8<7>;4FY<@%9TN$WNQ.@R]"=5\14JMN:PQSQ:,%[%O]
MA>F=H$OH^9"IOKNJ//:5VV+VV:6#?;-BUU?. ,_^*-V3@8N4D/@N+2M<K%E3
M(75AZ_-<S0MDOY6H9>O; I:I?,!)@(4[> JU$C]N*L8-0KIW?<5])!' >?SK
M/;S@?3B?:11_FI>(?7TD@YS1__WRHX;\YC:XKI"[^J\02MD8(_QBT -Z8<10
M("<;N2N28:JHV1CQ=C3$IR0)*&$L=4 07E:1.J[ +3X]N@<;.3P5"-BX^D]_
MC;CZGJ:W6I1ISE(G18RS1R"6CZJ%RF;@:LWJ>XS;:.D.#>NCA&;;%]BZ5(O-
MQ32;<*N)<R+G!9&]Q> 9YLAWD0DNR.1JG;I,+L#E@EO-<CU3\+@,_;X'XP8Q
MC1JLL9F!H>>FC'Q6>YTEG;<AC&-5Z[S <%NK/O.66C'V/6"0P;Q@$FW4,C(=
M6'M+>AO_JB17W.HVX.D76J5^9314IT'0:%O^P3$ZF*'C/2"V)2XH2F=B<'.*
M#>,*"M7SAT6$4]\[R\=2I#G<6_+5YUBM"/U^8+4A>ZW=#'TN>HTF.J IY-7?
M]SQN91BPNKU4*PS.Y1P(),H!^G*:"MK0C?9VHBU./5SK2^E<K)F36VSNN[%E
M?,'8!,\,#S=-&^KB/#AMQR_;CFC.Y_T4];MRI9D%,=* )P<()IJ=W"2.$.I$
M'6 (P(7M0>L #@CCS0=&0S]Q@(:.8**A8!M%<C]G?*3N%SE[X$AHZ]Q,MK]^
M7@0(TV?*-@3BD2U"[A2F;1 6FC1DVU'Z9<ZI'VZ@37_2KPU=QB[,;I'_+M&V
MM\'8N(O8T]V[=>F1[:F912L)E0I''1S1BZ\E#]P_Y\;58;$L]-8!G^@V_KIT
M&\;>N-JKO?%0S@U2.7W"/,JXX+$(^;"[TBXL'O*]>7$[G'WKCH$G#'Z#Z]P&
M&#A5Q6(E3.@I7->Z,C:>%UV01*_##K7*(LG:I-P!")/H2(.%U3%D[U(6<8%=
M&S$=3@EE- X(\DYH1DU]QZ">..;!4U<QV7/2WJ.NX>6$+I]["[9S_<-O[_;,
M64:?%(\^$N:M4%BZJ/3+&2%W(UOS6SHS8QL#]S[,:2\_?(NTLH.:>J94ADVC
MO<B6M0K<.YCN<_CF0HQ;!6<@&/<*Z\8Y7^,7C*.-TEUY?/^[SNL3$YJ8<8G2
MC0CQR<P$:7G.+&LAW@(C$&5.C1>H:#+X(%1[Y Z1[6/8W%928^6T>*;IBWJ?
MV ONZ%T"+9(4M),Y8OK=M9AFQB9Y? &'D;4E$P1#W+ERZT\)>$@K"K0@E"*2
MH!M),$HE!@A3[@!62]B.2FI*T$Q*V2OUS U0K'LO@^,1>DLGSH>M>APN3B;]
MYJYW<9''$AL:7 N88XY'XMO4NJ#V+3.:@)JHI0;7Z1_9CZWI'S'9['>:E1,S
MPG">P(NBR6MH/SUN6G<F!I=5;PO3O++WJBWXR6,Y78;[K;\:5$U]^P*<&V&F
MAG][FT.,G<X.:;MXE)LEW=6[:PWH=Y,T.H0)IT33DV>'GV@:C?=)T"9I8(BV
MBR.N""Y\F* RHHF2*)J_94A3[=0PV"FUG$4"%8W3,FZ6NIV#TRMQJMR@1)9^
MPIYEJ"^9A1E),P3_LG#W-!Y&C6^W]8WY/""]06=5H#0ALF[$D>=R8!KMVJ][
M=:/XEH91G\%$J7U.>:92".KH,ZL+_V!^VE4[V'^^D%M)E^?"-&#L"?T,MIET
M@SF]DR?#[9DYFIYQ>DT/@K"/^& ;;L#\KNB7NK3RFWYWX7V]^#$=QWSU_LV'
M:PL,,W7C5/U#C/(5E<I2V2+S+%-4SGZOZ2MU82/<1Q#-'BP5K!\!G,_2SXS5
M8***.15[MNTKXF0/?L-,K1CXI;8(R;0*L)P7U)CYDKP,AV6$^TEX3IIIY5I(
M8[4W_X53Q5-0V.UW]?BR]_,GMMN:&,M,9FX@PSC:57M0&NI''$L""UVJ*)>Z
M4GOS*S!KW/M/I#/%'3ZB>V_P=&:4X"]++-DB.W;+,Z[.GCR>F%>;',VN&>Z(
MVM./91N/"GUGQ%;Z]5%-@RF9T!'N_AWI%4U(]Q DS8FI."!$)@+9(2%LEIG#
M@JZ75/I5&<X6W?") <!+#-=KIQ=OA[&O KL3"+8A$DPX.+CPG3)*?%=<E7Q7
MK8H& _4\FI@S;^B'H^?J-*!!LGXB19C I>M"NF6XQC!&X2Q-I"THU):%6!/Z
MI>P[N:_DO)&'V=+M64B9-/S &+T?+$UPP64WO[]X?WTT,C_<KG/8!3*\%P3I
MH2Z3H?3M$ *,*,%* V& ]YG;-^-M2%HI1M;39K+=<XO43VB-&S_DX\>#*I^*
MT 12AK:O\$LI8>]WTK:MYM'VPND:J51I4X=.,,\C2=%'$]7FN'DN"A4$=VEA
M".3Y/.:^X+X!C'?4OX;?V1]-&28DJ<LB'#0RC\6!W]SJ3U<8AT83AM;@H+5L
M$46:0]&_RO+3*BKQ0 T& M#$HB2<:SD$O (A3<'_$'*D9&-DU6.YHO8Q<]3'
M]!PJ0\,P3TK-AO!-BKPAY)Y1[A9"1[6'><6RD#1*+"IJ4K2(LIF6'1OJ[.A0
MW<NC"IWV@FBI8=PN2A/#U:EA&DY6'60"]3**_5K5.(!0>$W0,XCCLND6$[V
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M"+'<K[L\5#SK^(N^3F3.B<S$SFBJDP>!A_D4V_%)>#:CP[,4YWJJ0R226G#
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MP<!ID2,\+E&!VS65+RBKC2]O ZN![MH6!8MF23B\"IQB#5@RN@Z9^_%SHG!
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M7R[X]O3Q*?CV/=*+3P\KE_0Q^JSVG$4\6,K,I_N<M[__[>GS!S4-&/$!/IR
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MV_6&18W+VU;/G9WLVYX0TM7U6HM*;QKTWW$WV&)S QX_BJF\D.7':ZJEM^!
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M*@RV<3(>5[51: )&S>W2>-_,9IIC_OL 7#4>JB=GYX]V[; %#1P9"AW2\),
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M2_"9%V"&5PPFU>0J*WZTJ9(YPX;6Q[]6]Y'%^.E#,XY^BO5*3MK"@\$65VZ
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MCM@"W6?T>8C:MZAED^KH15IYBJ^N4(U,T"#XQQ$XI=EBM8BT<HM4J CMAOM
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MF$C<C-9@LEP0@?][9I%D8OQ,VEGLYXC>/#KJ6H*Q+7 *^ 6NY?DYZ2GV@M^
M#(,Q'L1&ZFR&0YO36_:NN,YKM!?DJ1;J:J'/3[70>QO,;]TALB>N)U;(C-63
M.(1'P4SI7\[JQM?HX-">9TL)QTOFNL4V*M&JHH.,^825;OI['U'-#FQ5L+5:
MV_6*63M[+GTP-X+Z..DUQH\8UF*'@(NUC)24OX9[.\*IK_0JHDHE0FLB:@=&
MEQO#OHD^GX5,PO <2>+0%$C;NKI"W-#29,N58WOBYC>-%,4W*BO13,%\#;B
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M#:;=#/U; !<X:Z.-DBQ?^04^QF6YUU3<Y&?!\@Y5]Y3T?A^HN?VAM_Y9OQO
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MGUM0C^.GNR51C?9^>!Z=AF?=\#S>[?#L/S+HZ=F3_49JGK#:/P.K?2R9MV^
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MFP*^,\^6=,CB<Y-A-;^67H/U<IF1^_7[I:B+5.:Y7O]KA>"1M^C8(HZZ11!
MVS;\TQO,C-BNL0S>7S ?) 0@2@#<U4? P=;PE?0@O0,W&AML2] ;J-I3ZQ]A
M)'!4?M?VX_6A7SJMA6ZI3^S!18.QY,LL\0-+"FKE)2O_G)*)Y<04*B(=E149
MED/W6X966)+5RU73HY2D8F1P&I=3-V>J)Q8O2LF!]X2$?(JWMI1N@_5KHF\]
M=#2U'"ZVW73FUC2G!QU\1Q6_/BW1'ZI)V%U@ZJJV^_^W]Z6];6-9VG^%Z'K1
MD #&;YS5F<(,H-A*XF['-FRETO5I0(F4S40B-21E1_/KYVQWXR+)65JD2_VA
M*[8E\JYG/\\C#+MKX-M50@2YLH(XQP0Y+1\1Y&:YE&$K"< R^>3]\1D]\QC^
MX7-.0X\OUQ9[@RYT^+55,;;7DV?PXLJ31(8]7/[!JS&^- D6P00%C%B6QB\I
M2QGXL!47,L$B,CB8YNOQ:)YF*OHRT9AQMFC%AM]0(,'/0ZP#B+DXT/F#[NJ7
M/Q"5]T42>=?!+#*NG]3DX^I60WQ&[+GOE&"=/< ] L > >#'$ #*"D(=6-^Y
M!ZW/23I5+=,V]/US:(?NKK.4)8O+#>^LXZ%3GZQ(#-D=EETYBJMC#,R#:_6H
MI/;-6JEM&RQ4Z/&8IGZ[=NHT72^>+](\J@":*7>#NYNOEV.PP&(X2E'>9)\X
M*JM$N4KA*7X?<MI@^.K;A-0=G]5!#FX^# (^H@^]./)@+SV2W5C?738/BH((
M93M 9C:YC<(E;#))S7BG4K,Y=?[72S6]W*>:?D5Q0\<(=&N*&VJ\\O:6.EBE
M"(WAA.\N5["YNWUJ]DKH7_-H/L:'JQY<+^((F_ZH5>=@IUGNL 2C$R4(-6G,
M[M0C<$^?4Y*@P5%4:*(A6:L;XB^S]$DY%RM1J)^9:>4X4%TRM91S_6N Y_^"
MU&H=^M1/3[%^1^:K;EP_,:^US_INF?5]&$1%BV_5S\_[UAW1;MT"2SCK=F8K
M*NJ@?!$8%E77E*V,SA?<=HRH[@QKGG(4PB7KM)VN8[?$1+/R/4\+O&QY ;=4
MTJ%8:WNC9#D5XB(LT!H9@/TW=?TH)EHYC@C/8!9I3(+F7H%]G^-CZG/T6M#B
MJ#"P4!&9UBU-!(VYZ24K/WT6Z:RRK2\5F\*6!79ZRHI,XRS6G'P.F[=^8_:G
MMP.GM[ZZ)4(SG8(1&":/0NPT7&8>O'^&XYYBI.,6)D3\T[?I,L?#_^G@^L [
M26<S;*7L_;\7_LNG3WT8?=_KD9_ %X$[05H=J3B)PB5L$%S2-L0C?+$>65 T
MB 0=L[ 4(7X4F[XL"61B#+J$G3 380_SFJR(68A]OGZ?K_]QQ'[TDFY2/+5V
MUWGGD-[ ^]FU:BLU;J@*.7;)*5GO.^$M3INR[%W3*:\K,55)GJDPY5K?O1SH
MIAR8+C.,6;1 #DB%X";?S(1\--@9:J5VKJYM].XMWDT6[TY7"*L_4&SFR_$7
M"T)DGB91@8&(KBNF?3SK5X:]?TX\2[S\E7'RA_DD2^]),RO0+A@\.%GBG.7I
MC(O!(RRJS=']RL$AFT1.6$'$*#W5> O-Z&#<"C^;X3T0KP#%LO[JBFZ+#1U6
M^ZJF//D^3-%IDV%O3NW=JG^[6[5C[IY?Y%9)*]!6C]D$9D8NVG&SAW8 7UBK
M7A2.D&ZT@X/R))U.NR*OCUIP0KJOG/%9UGG<[NAUY(3L6J/O2X)-2?"KQU@2
MW!I/I;D[_QUFP@T#&Y4HD<28LA*X"V(F;9'V;$=%(!L6JI#U(DJUF-:E-?V:
MLD;LUE5\=HVUM7DUNX'24/RK9G%9;@?;^S.[(T",.16U"&)R?R=!?NM-XRPO
M5(5J^< QQ*K#7T(90]E$SD%R3Z^$;^C91 VF"1;AZY3M8CBAZBO6GQ_6Z\3:
MX> '\/-7^NGVN. <(V <Z4^AF</SXE+42P/VWL[Z/DX@NL"EN[W6TMYHQ."I
M:3*>J0$=65ON#(IF4 ? 52TYDC/AY%"_LR*\(H]+[ZC6>[N%W;7";\W9WTO%
M?6STQ\%OAO6(=DU7#4$NYHA"346[34!W:?8#8'@_=)'+\]"5YL><P*H42RS2
MS*XC7@,LPH-%,%[48HH%J3JX@\</_X)FZF*980=P+81*J^N$2D>B!<5"8H^L
MT1/H:E*^PB!&X:&W0P'5R!0CY6Q1-B",[UBN9)1/%:Z;:AUSI+(N1'],9L$2
MA]P;(\P/LUS#L=FG?/\J>J49VF9T:]?06A*Z^80AV:ED+]J/ -(25@)=09A$
M>J%YV7.CL$Q]<B/&/J]WG.0@/K!K:Y'.XDF=AVY[4CUY*>E1EBS>73!;Z@;)
M.)D@<S"%*^ #\W@YMX:E("1D4!:"OQG'),BR.**@2"#VLGJCD!TG$VU]X[#\
M4@FDCF9,TEP!CG];1 E;_4*7#,.3-4(I2U.TEB)+N9BV<2GZCT;E-X.>C.S<
M SLE-3Y'M_HT=A]OD3Z8@-H?^2KPO;F+X& P,@]6)>!I9O(';2O#/?J?98RG
MMP>_1N@U(G.>PO.HQD'^VL?F-GQF :-?CPC&S7EDZIKNO%5]7ZS3>E\AV$$A
MI!IT110TMYM2A$@(+@*YS3@C1-.+#2IW<X,B,_ \%I7:#+[S'64LBIRHQJVR
M%(7@1NE8WB2839:F-=1I?D9[$CYY$HW!SG?^<@[*X'.:$>"I@)+2UHY,:Z8W
M5*+7[M.G@UM!YFRG^&B)VF][Q2 ?V*/=$A!YO5_\=GKB?^!!CR=;C"<^B YV
MN1X^R@!QS<-TB;=N@@* <$&Y:^71&#+-H%E6A)I2!NLIX)R*P'9>.8>M^?2/
MW9XP0SAD<V!-+*L%S7%4W5P(E:2)-M\M##FJ:[#!X_AW+FC/50E0)W&PK@4P
M>!Y\C21353\V24UET8Q2EX0<K1\"K@*\ KX?HS'"%ABS,*;96M"1.L+##?.C
M-]['>62#:=295N"0?&$QFQ.?>S0)T+71&$339;',(O&6^/?+ GGN<WWJ-<@C
M+(8]CGT-A*F!>/T8:R!V#T'QLEL0%.>"\#XE3Y\;J2I@3KN%17LD*KL9CV*P
M!AE"Y7\D?KT1=TO%L9F/@5WN>E[5!7U)*O_@_VK"E1P,?RP;T-Q <6K7>)#>
MMC@S+. UF$^QE$"%O< 4?Z"=X$6E>!OK-)TG5*0 =7F&=HJ&UH22VNX-[KY_
MK(>H'EDXLQ*_C47WK5_*G7:+]3N"6UD1_"W(\_;]ANP+BU"PZ^<+!'R<8%:U
MK)44SS&)50NTK:KAM$B-"^\VR#W7^2+Q+4+620L1&2*-K* 6BC$55X!'$QI&
MBBJ&Q8&'F8%I$,_0YY!!5F<(WR<*<TP'I4DPGJUDNM;TZF=CFCO VX@(PO ^
M(,Q6RV62"'K#&'7EE@UW[WI6&"B%,0J_HXM"KCMV:A \8BN?!<[@%_#:)@AO
MYZ:K*%,D:\0+U@@&XM8R^AB]1P@TZE9@2B([A^7+1FE/E#<3PSIY-+-7.YC@
MS"C46MI+LTET/%(OC*81>>D$D.I[270#>Q04$1):%<6LM/1A%,Q,B+ZZ@;1\
MS&R2*Q=6E]V9(<"P8X[ETRW>0Q;L>^Q^O,>NYIJAZ*-6,>(.T*32<$OIW.=T
M/^H<!RRZL5P+3$=E8$-@O9BDB"D9QID.GP!\)X5 X<UFT8T.$CG9/6DI$XD-
MUR2.IIY%BZ9;W,-@'MS@G5%NA[2GF2$53+05W<!MFL?YDB-)4\QI2UT6_!:)
MI])%%NO15%! D1V.&IBP-.\2/@SZ9J5XJVS?BBK R,0']RS/]<R)H"J>-FT
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M=9YPH_XQ!H<I(JNTG[IZP;T:\K<'W@[3LZV:HZD$>A9DI',+C6WI3&T+F:?
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M)\TDBP:%/ H])KR?"R+05KG9_]72EF+$E<2,U6=55YB5V00\WW=6P5>?$R:
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M[VHY^<JAVI,@B2.D]S-&?WMG,T1SC&>RP4.93G_A,":\B@<9K>*K%[_/[@_
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M/%*ME3>(\B G*Y?8&1\\I(#-V<E@_T;?'A';/"?XF;8'G =^IO:J7[YXIL>
M,,PPDE"/BIIE"0O<=%CT6GV:[7FUX=PJ%2-1W=QJH^6$X,![/SP?7@W.O*OA
MV7!P/?1.+H;7WOG%R!O^:S0\/_%&%][QV>#TX[7W^</I\0=O]&'H'5\-3TY'
M%U?FP_\\O_CLP2^N/UU?#H]'^*WAOTZO1][IN??A]!K_]&%XY;T;_ '_&HSH
M*:/3CT/OXAU\<'C\:71Z_IY^*^/PY76G[^C9Y][;/^%!']6#/GZ"9W\8_#'T
M/@Y&PZO3P=G9G][@W3MX]_#$?N/U<#0Z&WX<GH^\SZ<C'O[)\"T,GN)K#O!0
M73!8SK%3C$"*'<_U9N$%-YR^Q(AZ<!UZ@[XV&02\02,T9CH(N4FKUH(.8L>U
MC=M7B:-P,D.P)\%ZT>G/M7*M!IF<W@Z'J_>VC\W;ZAE-CXAS(C$28[NBE[<V
M(11V>TQFBL\@_Q.*;++E2.A_>4 DEQB-3)/E]A,M;C.JR\"QA2AX.+7C>W?4
M9V_&+^'^W KD.)_'L8R7>9P($H:B=12<7Z>IPOEB[[AO@WL0R*(+LBEXK%M9
MBTXLUHH$H=Y8YAP44[Z0COF0D3&-PR7&A5:5K7+1\8W>P ZRHDSI\'8%%B\C
M @E8KXG@G07WOM8E-=$R-'5.;$-'<8+A DR"A+#"5_@8A@R72S<FY),[HALT
M@>>-NEMB*@0N(A1DH'T3L-)!59=($"7NYNNH&Y.62$S.I1%'OY2 H-&VY!!9
M"&X^8K8R'R-')REJYL"ZX E2IXRFO/'TZFWGI785;": P*!I CD 3-8W89(-
M]$Q@W9))O)AI")DO8$?G82P@T@^R?^I,'1H@K#.C8Z #AW(4(10*YCP-)3R+
MX#[X@2F9U842CPA[2H]=-PCT=W 8=-@%]CA7:*\@*"I@$563IFK!()I13.F5
M;824!@@B_/KE3-Q:)+#0_Q8O5K-NAEK-V [J%MJE9Z5KUDIA\Q5#&HEV8'8G
MPC/Z1@I*,1SW>:U)>]W#'V/$2<8MI'^**(F*%*<BG'7X!X75\Z 5IBS!=)GA
M5!1S!_U=+R7+%1T)0'T4$)@H#]:DNG@I*1F,3BZ;I&CS(*>P< +#$2\T6;%Y
M:!F%D*2SG-(5>X@X08M9A$'60Q6K*)U:/->(KVS9$ QNPI^'P6M8[W7>84G[
MQHF:LXUA0^"%B9KC78H@,.;OBA!;EL..3NR#O#K(^W(?Y/VIQ;Q8#6-1;Y1P
M^.V4,]^#M5R::[F250V.JOM@JZ?S%12ONI5N5A#0N\TWDYEBUUI5*AK60$#W
M[LG*T":[5BOD5PC6^H-PQO>T+QOWK&_P$X-,DX%5W:8:XI &PMV-K%HJ)L_X
MC:S'G2\YI3.DF3$29[QK_.M4<@LXXEET _I?\Z08LC+*'^EDT@0_00PI^PK
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MX;^,2&79TR9#[0VULMRZY%,L086D2'D(*U/$B?0S?="$&(GSG.&"3(H5-P4
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M !$              ( !     &%M9VXM,C R,3 Y,S N:'1M4$L! A0#%
M  @ $*%B4_ISB,$5%@  T/<  !$              ( !^N4" &%M9VXM,C R
M,3 Y,S N>'-D4$L! A0#%     @ $*%B4U8P;*KE&@  % 8! !4
M     ( !/OP" &%M9VXM,C R,3 Y,S!?8V%L+GAM;%!+ 0(4 Q0    ( !"A
M8E-_#CFM,X$  .N)!0 5              "  587 P!A;6=N+3(P,C$P.3,P
M7V1E9BYX;6Q02P$"% ,4    "  0H6)38J[/\F() 0 .\ H %0
M    @ &\F , 86UG;BTR,#(Q,#DS,%]L86(N>&UL4$L! A0#%     @ $*%B
M4UU1_#$EK   VZL' !4              ( !4:($ &%M9VXM,C R,3 Y,S!?
M<')E+GAM;%!+ 0(4 Q0    ( !"A8E-GT6Y7YIL! /GQ#0 :
M  "  :E.!0!A;6=N+65X,C=?,C R,3DS,#(Q>'$S+FAT;5!+ 0(4 Q0    (
M !"A8E.8K[9WU0@  '9-   8              "  <?J!@!A;6=N+65X,S%?
M,C R,3DS,'AQ,RYH=&U02P$"% ,4    "  0H6)3,95R1\T%   7)0  &
M            @ '2\P8 86UG;BUE>#,R7S(P,C$Y,S!X<3,N:'1M4$L%!@
0   )  D 7@(  -7Y!@    $!

end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
